CN111117870B - Liver cancer cell collector - Google Patents

Liver cancer cell collector Download PDF

Info

Publication number
CN111117870B
CN111117870B CN202010083797.1A CN202010083797A CN111117870B CN 111117870 B CN111117870 B CN 111117870B CN 202010083797 A CN202010083797 A CN 202010083797A CN 111117870 B CN111117870 B CN 111117870B
Authority
CN
China
Prior art keywords
cavity
cancer cell
liver cancer
cell collector
joint
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202010083797.1A
Other languages
Chinese (zh)
Other versions
CN111117870A (en
Inventor
王萌
张娣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wang Meng
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202010083797.1A priority Critical patent/CN111117870B/en
Publication of CN111117870A publication Critical patent/CN111117870A/en
Application granted granted Critical
Publication of CN111117870B publication Critical patent/CN111117870B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C12M33/06Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles for multiple inoculation or multiple collection of samples

Abstract

The invention discloses a liver cancer cell collector, which comprises an outer cylinder and an inner cylinder, wherein the outer cylinder and the inner cylinder are both cylindrical, a first cavity is formed in the outer cylinder along the axis direction of the outer cylinder, the inner cylinder is inserted into the first cavity and can slide in the first cavity, a second cavity is formed in the inner cylinder along the axis direction of the inner cylinder in a penetrating manner, a plugging mechanism is fixedly connected in the first cavity, one end of the plugging mechanism extends into the second cavity, a rotary table is rotatably arranged at one end of the inner cylinder far away from the outer cylinder, a joint is fixedly connected on the end face of the rotary table far away from the inner cylinder, the joint is of a hollow structure, the second cavity is communicated with the joint, the number of the joints is multiple, a limiting mechanism is arranged in the rotary table, and a limiting groove is formed in the. The invention can be conveniently operated by a user in use through a series of structures, and the sampling precision is improved.

Description

Liver cancer cell collector
Technical Field
The invention relates to the technical field of samplers, in particular to a liver cancer cell collector.
Background
In modern society, cancer seriously endangers human life and health, and in order to cure cancer, the cancer must be cultured and isolated when being researched. When researchers complete the culture of cancer cells, a collector is needed to collect and transfer the cancer cells. Most of the existing collectors have the problems of inconvenient use and low collection precision, so that the existing collectors cannot be conveniently used by researchers, and the research of the researchers on cancer cells is seriously influenced.
Disclosure of Invention
The invention aims to provide a liver cancer cell collector to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a liver cancer cell collector comprises an outer barrel and an inner barrel, wherein the outer barrel and the inner barrel are both cylindrical, a first cavity is formed in the outer barrel along the axis direction, the inner barrel is inserted into the first cavity and can slide in the first cavity, a second cavity is formed in the inner barrel and penetrates through the inner barrel along the axis direction, a plugging mechanism is fixedly connected into the first cavity, one end of the plugging mechanism extends into the second cavity, a rotary disc is rotatably arranged at one end, away from the outer barrel, of the inner barrel, a joint is fixedly connected onto the end face, away from the inner barrel, of the rotary disc and is of a hollow structure, the second cavity is communicated with the joints, the number of the joints is multiple, a limiting mechanism is arranged in the rotary disc, a limiting groove is formed in the inner barrel, and when one of the joints is communicated with the second cavity, the limiting mechanism can enter the limiting groove, the outer barrel is also provided with a first through hole.
Furthermore, an external thread is arranged on the outer wall of the inner cylinder, and an internal thread matched with the external thread is arranged on the inner wall of the outer cylinder.
Furthermore, the outer wall of the inner cylinder is also provided with scales.
Furthermore, the plugging mechanism comprises a fixed frame and a plug, the fixed frame is of a rod-shaped structure, one end of the fixed frame is fixedly connected to the outer barrel, the other end of the fixed frame is fixedly connected to the plug, and the plug extends into the second cavity.
Further, stop gear includes spring and stopper, offers the recess that is used for installing spring and stopper on the carousel, and the one end of recess is the opening form, the spring rigid coupling is in the recess, and the tip of stopper can stretch outside the recess and enter into in the spacing groove in order to block the carousel and continue to rotate.
Furthermore, the limiting block is of a spherical structure.
Furthermore, the number of the joints is two, connecting holes are formed in the rotary disc, and the second cavity is communicated with the joints through the connecting holes.
Furthermore, a baffle plate used for plugging the connecting hole is arranged in the turntable, a rotating shaft is fixedly connected on the baffle plate, and a second through hole is formed in the baffle plate.
Further, the baffle is disc-shaped.
Furthermore, the joint is of a conical structure, and the free end of the joint is a smaller end.
Compared with the prior art, the invention has the beneficial effects that: (1) the outer cylinder and the inner cylinder are arranged, so that a user can conveniently collect cancer cell samples, the inner cylinder and the outer cylinder are convenient to adjust, the use of researchers can be facilitated, and the adjustment mode between the outer cylinder and the inner cylinder adopts a thread mode, so that the collection precision of cancer cells can be improved; (2) by arranging the turntable and the joint, a plurality of samples can be conveniently taken by a researcher at one time when the device is used, and the joint is conical, so that the device can be suitable for collecting gun heads with various sizes; (3) through being provided with stop gear, can be when this device uses for connect and second cavity intercommunication each other, avoided when gathering cancer cell, the condition of taking place gas leakage. The use of baffle can use the back at a joint, carries out the shutoff to it, has guaranteed that it can not appear the condition of gas leakage when another joint is gathering cancer cell sample.
Drawings
FIG. 1 is a schematic diagram of the whole structure of a liver cancer cell collector of the present invention.
FIG. 2 is a schematic view of the internal structure of the outer cylinder, the inner cylinder and the turntable.
Fig. 3 is a schematic view of the internal structure of the turntable.
Fig. 4 is an enlarged schematic view of the baffle.
Fig. 5 is an enlarged schematic view of a portion a in fig. 2.
In the figure: 1. an outer cylinder; 2. an inner barrel; 3. a turntable; 4. a joint; 5. an external thread; 6. calibration; 7. a first cavity; 8. a fixed mount; 9. a plug; 10. a second cavity; 11. a first through hole; 12. connecting holes; 13. a rotating shaft; 14. a baffle plate; 15. a second through hole; 16. a groove; 17. a spring; 18. a limiting block; 19. a limiting groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical scheme of a liver cancer cell collector: the sample extraction device comprises an outer barrel 1 and an inner barrel 2, wherein the outer barrel 1 and the inner barrel 2 are both cylindrical, a first cavity 7 is formed in the outer barrel 1 along the axis direction, the inner barrel 2 is inserted into the first cavity 7, the inner barrel 2 can slide in the first cavity 7 in various modes, such as the matching of a gear and a rack, the use of threads and the like, a second cavity 10 is formed in the inner barrel 2 in a penetrating manner along the axis direction, a plugging mechanism is fixedly connected in the first cavity 7 and can separate the second cavity 10 to divide the second cavity 10 into an upper cavity and a lower cavity which are not connected with each other, the structure of the part is equivalent to that of a syringe, after the relative positions of the inner barrel 2 and the outer barrel 1 are changed, the plugging mechanism performs air suction, so that a sample is extracted, one end of the plugging mechanism extends into the second cavity 10, keep away from outer tube 1 at inner tube 2 one serve rotatable carousel 3 that is provided with, and the rigid coupling has joint 4 on the terminal surface of inner tube 2 is kept away from at carousel 3, joint 4's use, can convenience of customers install the sample rifle head, joint 4 is hollow structure, second cavity 10 communicates with joint 4, the quantity that connects 4 is a plurality of, be provided with stop gear in carousel 3, a spacing groove 19 has been seted up on inner tube 2, when one of them connects 4 and second cavity 10 is linked together, stop gear can enter into spacing groove 19, first through-hole 11 has still been seted up on outer tube 1, first through-hole 11 is linked together first cavity 7 with the external world, it can be smooth to have guaranteed that blocking mechanism bleeds to second cavity 10.
When the device is used, a user inserts the collection gun head into the joint 4, then rotates the outer barrel 1, the outer barrel 1 can move up and down along the inner barrel 2, the plugging mechanism slides upwards in the second cavity 10 when the outer barrel 1 moves, at the moment, the second cavity 10 sucks air from the lower part, and the collection gun head is located in the cancer cell culture solution, so that the cancer cell culture solution enters the collection gun head. After a required sample is collected in one of the collection gun heads, the user rotates the rotary disc 3, and when the next gun head is just communicated with the second cavity 10, the limiting mechanism enters the limiting groove 19, so that the user is reminded to stop rotating the rotary disc 3, and the sampling operation is repeated.
Be provided with external screw thread 5 on the outer wall of inner tube 2, be provided with on the inner wall of outer tube 1 with external screw thread 5 complex internal thread, this device adopts external screw thread 5 and internal screw thread fit mode, has improved the precision of sample, and this kind of structure is adjusted comparatively conveniently.
Still be provided with scale 6 on the outer wall of inner tube 2, the use of scale 6 can be mastered by the volume of the audio-visual sample of convenience of customers.
The plugging mechanism comprises a fixed frame 8 and a plug 9, the fixed frame 8 is of a rod-shaped structure, one end of the fixed frame 8 is fixedly connected to the outer barrel 1, the other end of the fixed frame 8 is fixedly connected to the plug 9, and the plug 9 extends into the second cavity 10.
The limiting mechanism comprises a spring 17 and a limiting block 18, a groove 16 used for mounting the spring 17 and the limiting block 18 is formed in the turntable 3, one end of the groove 16 is open, the spring 17 is fixedly connected in the groove 16, and the end part of the limiting block 18 can extend out of the groove 16 and enter a limiting groove 19 to prevent the turntable 3 from continuing to rotate.
The stop block 18 is of a spherical structure.
The number of the joints 4 is two, a connecting hole 12 is formed in the rotary disc 3, and the second cavity 10 is communicated with the joints 4 through the connecting hole 12.
A baffle plate 14 for blocking the connecting hole 12 is arranged in the rotary disc 3, a rotating shaft 13 is fixedly connected on the baffle plate 14, and a second through hole 15 is arranged on the baffle plate 14.
Baffle 14 is discoid, and baffle 14 not only can carry out the shutoff to connecting hole 12, can also play sealed effect to the sample rifle head, avoids accomplishing and being changeed away the back at its sample, the condition of taking place to leak.
The joint 4 is of a conical structure, the free end of the joint is a smaller end, and the conical joint 4 can adapt to sampling gun heads of different sizes, so that the device is wider in application range.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. A liver cancer cell collector is characterized in that: comprises an outer barrel (1) and an inner barrel (2), wherein the outer barrel (1) and the inner barrel (2) are cylindrical, a first cavity (7) is formed in the outer barrel (1) along the axis direction, the inner barrel (2) is inserted into the first cavity (7), the inner barrel (2) can slide in the first cavity (7), a second cavity (10) is formed in the inner barrel (2) along the axis direction, a plugging mechanism is fixedly connected in the first cavity (7), one end of the plugging mechanism extends into the second cavity (10), a rotary table (3) is rotatably arranged at one end of the inner barrel (2) far away from the outer barrel (1), a joint (4) is fixedly connected on the end face of the rotary table (3) far away from the inner barrel (2), the joint (4) is of a hollow structure, the second cavity (10) is communicated with the joint (4), and the joints (4) are multiple in number, the inner barrel (2) is provided with a limiting groove (19), when one of the joints (4) is communicated with the second cavity (10), the limiting mechanism can enter the limiting groove (19), and the outer barrel (1) is further provided with a first through hole (11).
2. The liver cancer cell collector of claim 1, wherein: the outer wall of the inner barrel (2) is provided with an external thread (5), and the inner wall of the outer barrel (1) is provided with an internal thread matched with the external thread (5).
3. The liver cancer cell collector of claim 1, wherein: the outer wall of the inner cylinder (2) is also provided with scales (6).
4. The liver cancer cell collector of claim 1, wherein: the plugging mechanism comprises a fixing frame (8) and a plug (9), the fixing frame (8) is of a rod-shaped structure, one end of the fixing frame (8) is fixedly connected to the outer barrel (1), the other end of the fixing frame is fixedly connected to the plug (9), and the plug (9) extends into the second cavity (10).
5. The liver cancer cell collector of claim 1, wherein: stop gear includes spring (17) and stopper (18), offers recess (16) that are used for installing spring (17) and stopper (18) on carousel (3), and the one end of recess (16) is the opening form, spring (17) rigid coupling is in recess (16), and the tip of stopper (18) can stretch outside recess (16) and enter into in order to block carousel (3) and continue to rotate in spacing groove (19).
6. The liver cancer cell collector of claim 5, wherein: the limiting block (18) is of a spherical structure.
7. The liver cancer cell collector of claim 1, wherein: the number of the joints (4) is two, connecting holes (12) are formed in the rotary disc (3), and the second cavity (10) is communicated with the joints (4) through the connecting holes (12).
8. The liver cancer cell collector of claim 7, wherein: a baffle (14) used for plugging the connecting hole (12) is arranged in the rotary disc (3), a rotating shaft (13) is fixedly connected to the baffle (14), and a second through hole (15) is formed in the baffle (14).
9. The liver cancer cell collector of claim 8, wherein: the baffle (14) is disc-shaped.
10. The liver cancer cell collector of claim 1, wherein: the joint (4) is of a conical structure, and the free end of the joint is a smaller end.
CN202010083797.1A 2020-02-10 2020-02-10 Liver cancer cell collector Active CN111117870B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010083797.1A CN111117870B (en) 2020-02-10 2020-02-10 Liver cancer cell collector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010083797.1A CN111117870B (en) 2020-02-10 2020-02-10 Liver cancer cell collector

Publications (2)

Publication Number Publication Date
CN111117870A CN111117870A (en) 2020-05-08
CN111117870B true CN111117870B (en) 2020-11-27

Family

ID=70492457

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010083797.1A Active CN111117870B (en) 2020-02-10 2020-02-10 Liver cancer cell collector

Country Status (1)

Country Link
CN (1) CN111117870B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112779139B (en) * 2020-12-29 2024-02-13 麦迪森(江苏)医学研究有限公司 Mesenchymal stem cell cryopreservation device and method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102537417A (en) * 2010-12-15 2012-07-04 克罗内斯股份公司 Fluid-rotating distributor
CN206396202U (en) * 2016-12-22 2017-08-11 深圳市第二人民医院 A kind of cellular collector
KR101856755B1 (en) * 2017-05-12 2018-05-11 주식회사 신우이앤티 Turn table type chemical feeder
CN209379018U (en) * 2019-01-16 2019-09-13 北京大学 A kind of bull liquid-transfering gun
CN209422661U (en) * 2018-09-19 2019-09-24 北京新星靓京广医疗美容医院有限公司 A kind of Self-body fat transplanting fat-cell acquisition screening syringe

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102537417A (en) * 2010-12-15 2012-07-04 克罗内斯股份公司 Fluid-rotating distributor
CN206396202U (en) * 2016-12-22 2017-08-11 深圳市第二人民医院 A kind of cellular collector
KR101856755B1 (en) * 2017-05-12 2018-05-11 주식회사 신우이앤티 Turn table type chemical feeder
CN209422661U (en) * 2018-09-19 2019-09-24 北京新星靓京广医疗美容医院有限公司 A kind of Self-body fat transplanting fat-cell acquisition screening syringe
CN209379018U (en) * 2019-01-16 2019-09-13 北京大学 A kind of bull liquid-transfering gun

Also Published As

Publication number Publication date
CN111117870A (en) 2020-05-08

Similar Documents

Publication Publication Date Title
CN111117870B (en) Liver cancer cell collector
CN209624614U (en) A kind of blood glucose meter of blood sampling detection one
CN112190291A (en) Quantitative sampling device for collecting piglet intestinal microecological sample
CN114518261A (en) Blood detection device
CN214088466U (en) Antibiotic antibacterial concentration detection uses quick analytical equipment of medicine
CN212410180U (en) Medical science inspection sampling device
CN213680629U (en) Medical sperm motility detect reagent box
CN111841691A (en) Medical test blood sample sampling device and operation method thereof
CN219886082U (en) Sampling device for human stem cell technical research
CN113261957A (en) Sampling device for serum collection
CN216473212U (en) Intestinal flora detection device
CN215209426U (en) Novel culture medium for genetic engineering
CN209377632U (en) A kind of new medical clinical tumor sampler
CN219996640U (en) Atmospheric sampling equipment for high-precision environment detection
CN220559288U (en) Installation mechanism of traditional Chinese medicine inspection test tube
CN208582440U (en) A kind of medical test sampler
CN216063367U (en) Blood cell tester for medical treatment
CN217042692U (en) Test-tube rack convenient for connecting blood sampling disc
CN220677917U (en) Blood sampling tube specimen holder convenient to deposit
CN219302218U (en) Alga detection sample inlet and outlet mechanism
CN212845419U (en) Blood glucose meter test paper all-in-one machine
CN212438683U (en) Oral cavity sampler for physical examination center
CN215296823U (en) Water environmental management is with multiple spot quality of water sampling device
CN220231201U (en) Thermal desorption instrument convenient for sample detection and placement
CN219297522U (en) Specific gene fragment detection device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information

Address after: 430063 180 Donghu Road, Wuchang District, Wuhan City, Hubei Province

Applicant after: Zhang Di

Address before: 250000 School of Biomedical Engineering, Shandong First Medical University, No. 6699, Qingdao Road, Huaiyin District, Jinan City, Shandong Province

Applicant before: Zhang Di

CB02 Change of applicant information
CB03 Change of inventor or designer information

Inventor after: Wang Meng

Inventor after: Zhang Di

Inventor before: Zhang Di

CB03 Change of inventor or designer information
TA01 Transfer of patent application right

Effective date of registration: 20201104

Address after: Department of oncology, Jining first people's Hospital, 6 Jiankang Road, Rencheng District, Jining City, Shandong Province

Applicant after: Wang Meng

Address before: 430063 180 Donghu Road, Wuchang District, Wuhan City, Hubei Province

Applicant before: Zhang Di

TA01 Transfer of patent application right
GR01 Patent grant
GR01 Patent grant