CN111110802A - Toad paste and its preparing process and application - Google Patents
Toad paste and its preparing process and application Download PDFInfo
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- CN111110802A CN111110802A CN201811286021.9A CN201811286021A CN111110802A CN 111110802 A CN111110802 A CN 111110802A CN 201811286021 A CN201811286021 A CN 201811286021A CN 111110802 A CN111110802 A CN 111110802A
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- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention discloses a toad paste and a preparation method and application thereof, wherein the toad paste is prepared from 300-500 parts by mass of de-heading toad, 30-50 parts by mass of frankincense, 30-50 parts by mass of costus root, 10-30 parts by mass of cassia bark, 20-40 parts by mass of cinnamon leaf, 10-20 parts by mass of iron vine, 10-20 parts by mass of raw kusnezoff monkshood root, 1-3 parts by mass of radix angelicae pubescentis, 6-10 parts by mass of galangal, 1-3 parts by mass of illicium henryi, 10-20 parts by mass of Chinese angelica, 10-15 parts by mass of radix stephaniae tetrandrae, 10-20 parts by mass of garden balsam stem, 15-25 parts by mass of myrrh, 1-3 parts by mass of menthol, 5-10 parts by mass of safflower and 1-5 parts by mass of raw radix aconiti. The toad paste provided by the invention not only has the functions of treating carbuncle-abscess, pyogenic infections, furuncle, scrofula and common small sores and furuncles, but also has short treatment time and good curative effect on the carbuncle-abscess.
Description
Technical Field
The invention belongs to the technical field of toad paste, and particularly relates to toad paste as well as a preparation method and a use method thereof.
Background
Toad is also known as toad h ma. Amphibian has many pimples on the body surface and poisonous glands in them, commonly called toad, balsam and scab. The method is divided into two types of Chinese big toads and black-orbit toads in China. The toad venom and toad skin extracted from the toad skin are medicinal materials which are in short supply in China.
The toad can be prepared into toad paste, which is mainly used for treating sore swelling, carbuncle cellulitis, scrofula and other diseases, the current prescription is that 1 toad (for removing head), lime and sulfur (separately ground) half and two, frankincense (separately ground) half and two, costus root half and two, cassia bark (for removing rough skin) half and 1 nidus vespae (for burning ash) are prepared into powder, clear oil 1 and clear oil 1 are used, the powder is mixed and placed into a porcelain bowl for being contained, soup is boiled in the small paste, and the ointment is prepared without stirring hands.
The toad ointment is applied to various infections, such as carbuncle, cellulitis, pyogenic infections, furuncle, scrofula and common small sores and furuncles, and can achieve the treatment effect on the infections, the cure rate is about 70 percent, the treatment time is about 18 to 22 days, and the treatment time is long.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide the toad paste, and the toad paste is prepared by changing the formula and the preparation method, so that the technical effects of shortening the treatment time of the carbuncle and improving the cure rate are achieved.
The invention also aims to provide a preparation method of the toad paste.
The invention also aims to provide a using method of the toad paste.
The purpose of the invention is realized by the following technical scheme.
A toad paste is prepared from 300-500 parts by mass of de-heading toad, 30-50 parts by mass of frankincense, 30-50 parts by mass of elecampane, 10-30 parts by mass of cassia bark, 20-40 parts by mass of cinnamon leaf, 10-20 parts by mass of Japanese climbing fern vine, 10-20 parts by mass of raw kusnezoff monkshood root, 1-3 parts by mass of radix angelicae pubescentis, 6-10 parts by mass of galangal, 1-3 parts by mass of illicium henryi, 10-20 parts by mass of Chinese angelica, 10-15 parts by mass of radix stephaniae tetrandrae, 10-20 parts by mass of garden balsam stem, 15-25 parts by mass of myrrh, 1-3 parts by mass of menthol, 5-10 parts by mass of safflower and 1-5 parts by mass of raw radix aconiti.
In the technical scheme, the de-heading toad is 300-400 parts by mass, the frankincense is 45-50 parts by mass, the costustoot is 30-35 parts by mass, the cinnamon is 25-30 parts by mass, the cinnamon leaves are 25-29 parts by mass, the iron rattan is 10-13 parts by mass, the raw kusnezoff monkshood root is 10-13 parts by mass, the radix angelicae pubescentis 1-3 parts by mass, the galangal is 6-7 parts by mass, the illicium henryi is 1-3 parts by mass, the angelica sinensis is 10-13 parts by mass, the radix stephaniae tetrandrae is 10-11 parts by mass, the garden balsam stem is 10-13 parts by mass, the myrrh is 15-19 parts by mass, the menthol is 1-2 parts by mass, the safflower is 5-7 parts by mass, and the raw radix aconiti is 1-3 parts by mass.
In the technical scheme, the de-heading toad is 400-450 parts by mass, the frankincense is 40-45 parts by mass, the costustoot is 35-45 parts by mass, the cinnamon is 15-25 parts by mass, the cinnamon leaves are 27-32 parts by mass, the iron rattan is 14-18 parts by mass, the raw kusnezoff monkshood root is 14-16 parts by mass, the radix angelicae pubescentis 1-3 parts by mass, the galangal is 8-9 parts by mass, the illicium henryi is 1-3 parts by mass, the angelica sinensis is 14-16 parts by mass, the radix stephaniae tetrandrae is 12-13 parts by mass, the garden balsam stem is 14-16 parts by mass, the myrrh is 16-23 parts by mass, the menthol is 1-1.5 parts by mass, the safflower is 5-8 parts by mass, and the raw radix aconiti is 2-4 parts by mass.
In the technical scheme, the de-heading toad is 400-500 parts by mass, the frankincense is 30-44 parts by mass, the costus root is 45-50 parts by mass, the cinnamon is 10-15 parts by mass, the cinnamon leaves are 33-40 parts by mass, the iron rattan is 19-20 parts by mass, the raw kusnezoff monkshood root is 17-20 parts by mass, the radix angelicae pubescentis 1-3 parts by mass, the galangal is 9-10 parts by mass, the illicium henryi is 1-3 parts by mass, the angelica sinensis is 17-20 parts by mass, the radix stephaniae tetrandrae is 13-15 parts by mass, the garden balsam stem is 17-20 parts by mass, the myrrh is 20-25 parts by mass, the menthol is 1-1.5 parts by mass, the safflower is 9-10 parts by mass, and the raw radix aconiti is 4-5 parts by mass.
The preparation method of the toad paste comprises the following steps:
1) removing the skin and viscera of the de-heading toad, and drying at 60-80 ℃ for at least 24 hours to obtain dried toads;
2) mechanically pulverizing the dried toad, frankincense, costustoot, cassia bark, cinnamon leaves, iron vines, raw kusnezoff monkshood roots, radix angelicae pubescentis, galangal, illicium japonicum, angelica sinensis, radix stephaniae tetrandrae, garden balsam stems, myrrh, menthol, safflower and raw radix aconiti, sieving with a 50-100-mesh sieve, putting into 400-900 parts by mass of water, preserving heat at 100 ℃ for 0.5-1 hour, and filtering to obtain an extracting solution;
3) heating and concentrating the extracting solution to obtain an extract with the relative density of 1.2-1.3;
4) and uniformly mixing the extract with glycerol, and heating at 30-70 ℃ for 1-4 hours to obtain the toad paste, wherein the ratio of the extract to the glycerol is 1: (0.4-1.2).
In the step 1), the drying temperature is 65-75 ℃.
In the step 1), the drying time is 24-36 hours.
In the step 2), the amount of the water is 500 to 800 parts by mass, preferably 600 to 700 parts by mass.
In the step 4), the extract is uniformly mixed with glycerol and heated at 40-50 ℃ for 1-2 hours.
In the step 4), the ratio of the extract to the glycerin is 1: (0.6-1).
The application method of the toad cream comprises the steps of coating the toad cream on a wound surface, wherein the thickness of the toad cream is 2-5 mm, and covering the wound surface with gauze for 24 hours.
In the technical scheme, the water is kept for 24 hours each time and is continuously used for 5-12 days.
Compared with the prior art, the toad paste disclosed by the invention has the functions of treating carbuncle-abscess, pyogenic infections, furuncle, scrofula and common small sores and furuncles, and is short in time and good in curative effect for treating the carbuncle-abscess.
Detailed Description
The technical scheme of the invention is further explained by combining specific examples.
A toad paste is prepared from 300-500 parts by mass of de-heading toad, 30-50 parts by mass of frankincense, 30-50 parts by mass of elecampane, 10-30 parts by mass of cassia bark, 20-40 parts by mass of cinnamon leaf, 10-20 parts by mass of Japanese climbing fern vine, 10-20 parts by mass of raw kusnezoff monkshood root, 1-3 parts by mass of radix angelicae pubescentis, 6-10 parts by mass of galangal, 1-3 parts by mass of illicium henryi, 10-20 parts by mass of Chinese angelica, 10-15 parts by mass of radix stephaniae tetrandrae, 10-20 parts by mass of garden balsam stem, 15-25 parts by mass of myrrh, 1-3 parts by mass of menthol, 5-10 parts by mass of safflower and 1-5 parts by mass of raw radix aconiti.
According to the toad paste, the head-removed toad, the frankincense, the costustoot, the cassia bark, the cinnamon leaves, the iron vines, the raw kusnezoff monkshood roots, the radix angelicae pubescentis, the galangal, the illicium, the angelica, the radix stephaniae tetrandrae, the garden balsam stems, the myrrh, the menthol, the safflower and the raw radix aconiti are selectively combined, and all kinds of medicines generate a synergistic effect, so that the treatment time of the carbuncle can be shortened and the treatment effect can be improved, wherein the effect of removing the head and eliminating the cellulitis is achieved because the toad has the effects of detoxifying, removing the stagnation, removing the food; olibanum is selected because it has effects of regulating qi, promoting blood circulation, relieving pain, eliminating swelling, and promoting granulation; radix aucklandiae is selected because it has effects of activating qi-flowing and relieving pain; the cinnamon is selected because the cinnamon has the functions of warming the middle-jiao to dispel cold, regulating qi and relieving pain; the cinnamon leaves are selected because the cinnamon leaves have the functions of warming the middle-jiao and dispelling cold, and the iron vines are selected because the iron vines have the functions of promoting blood circulation, dispelling wind and removing dampness; the raw kusnezoff monkshood root is selected for its efficacy of dispelling wind, removing dampness and relieving pain. The radix angelicae pubescentis is selected because of its efficacy of dispelling wind, removing dampness, and relieving pain, arthralgia and pain. Galangal is selected because of its efficacy of dispelling cold and relieving pain, and illicium henryi is selected because of its efficacy of promoting qi circulation, relieving pain, promoting blood circulation and removing blood stasis; the angelica is selected because of the effects of enriching the blood and activating the blood; stephania tetrandra is selected because of its efficacy of dispelling wind, alleviating pain, inducing diuresis and reducing edema. The garden balsam stem is selected because of the effects of resisting inflammation, sterilizing and astringing wound surfaces; myrrh is chosen because of its functions of removing blood stasis, relieving pain, detumescence and promoting granulation. Menthol is selected because of its antipruritic effect; safflower is selected because of its efficacy of promoting blood circulation and removing blood stasis to relieve pain. Unprocessed radix aconiti is selected because it has the functions of promoting blood circulation to restore menstrual flow, dispelling wind and removing dampness. The 17 medicines are mutually cooperated to generate the effect, and the technical effects of shortening the treatment time of the carbuncle and the cellulitis and improving the cure rate are jointly generated.
Examples 1 to 3
The preparation method of the toad paste comprises the following steps:
1) preparing traditional Chinese medicines according to the mass parts in the table 1, removing the skin and viscera of the de-heading toads, and drying at 60 ℃ for 24 hours to obtain dried toads;
2) mechanically pulverizing dried Bufo siccus and Olibanum, radix aucklandiae, cortex Cinnamomi Japonici, folium Cinnamomi, caulis Fibraureae, radix Aconiti Kusnezoffii, radix Angelicae Pubescentis, rhizoma Alpiniae Officinarum, herba Boehmeriae Longispicae, radix Angelicae sinensis, radix Stephaniae Tetrandrae, caulis et folium Gaultheriae Yunnanensis, Myrrha, Mentholum, Carthami flos and radix Aconiti in Table 1, sieving with 50 mesh sieve, adding into 500 parts by mass of water, keeping the temperature at 100 deg.C for 0.5 hr, and filtering to obtain extractive solution;
3) heating and concentrating the extracting solution to obtain an extract with the relative density of 1.23;
4) and (3) uniformly mixing the extract with glycerol, and heating at 40 ℃ for 2 hours to obtain the toad paste, wherein the ratio of the extract to the glycerol is 1: 0.6.
TABLE 1
Examples 4 to 6
The preparation method of the toad paste comprises the following steps:
1) preparing traditional Chinese medicines according to the mass parts in the table 2, removing the skin and viscera of the de-heading toads, and drying at 75 ℃ for 20 hours to obtain dried toads;
2) mechanically pulverizing dried Bufo siccus and Olibanum, radix aucklandiae, cortex Cinnamomi Japonici, folium Cinnamomi, caulis Fibraureae, radix Aconiti Kusnezoffii, radix Angelicae Pubescentis, rhizoma Alpiniae Officinarum, herba Boehmeriae Longispicae, radix Angelicae sinensis, radix Stephaniae Tetrandrae, caulis et folium Gaultheriae Yunnanensis, Myrrha, Mentholum, Carthami flos and radix Aconiti in Table 2, sieving with 50 mesh sieve, placing into 700 parts by mass of water, keeping the temperature at 100 deg.C for 1 hr, and filtering to obtain extractive solution;
3) heating and concentrating the extracting solution to obtain an extract with the relative density of 1.28;
4) and (3) uniformly mixing the extract with glycerol, and heating at 40 ℃ for 2 hours to obtain the toad paste, wherein the ratio of the extract to the glycerol is 1: 0.7.
TABLE 2
Examples 7 to 8
The preparation method of the toad paste comprises the following steps:
1) preparing traditional Chinese medicines according to the mass parts in the table 3, removing the skin and viscera of the de-heading toads, and drying at 80 ℃ for 12 hours to obtain dried toads;
2) mechanically pulverizing dried Bufo siccus and Olibanum, radix aucklandiae, cortex Cinnamomi Japonici, folium Cinnamomi, caulis Fibraureae, radix Aconiti Kusnezoffii, radix Angelicae Pubescentis, rhizoma Alpiniae Officinarum, herba Boehmeriae Longispicae, radix Angelicae sinensis, radix Stephaniae Tetrandrae, caulis et folium Gaultheriae Yunnanensis, Myrrha, Mentholum, Carthami flos and radix Aconiti in Table 3, sieving with 50 mesh sieve, placing into 800 parts by mass of water, keeping the temperature at 100 deg.C for 1 hr, and filtering to obtain extractive solution;
3) heating and concentrating the extracting solution to obtain an extract with the relative density of 1.25;
4) and (3) uniformly mixing the extract with glycerol, and heating at 40 ℃ for 2 hours to obtain the toad paste, wherein the ratio of the extract to the glycerol is 1: 0.8.
TABLE 3
And (3) carrying out a specific clinical test, coating the toad ointment of the embodiment 1-8 on the wound surface, wherein the thickness of the toad ointment is 3mm, and covering the wound surface with gauze, wherein the wound surface is kept for 24 hours and continuously used for a plurality of days.
In each example, 3 patients with carbuncle and cellulitis were selected, each patient was tested 3, 10 and 15 days after using toad paste, and the specific clinical test results were as follows:
when tested on the 3 rd day, the induration of the affected part of 24 patients with carbuncle becomes soft obviously and becomes smaller gradually; when the test is carried out on the 10 th day, the induration of the affected part of 22 carbuncle-abscess patients disappears, and the induration of the affected part of the rest two carbuncle-abscess patients becomes smaller again on the basis of the detection condition of the 3 rd day; on day 15, the induration of the affected area disappeared in the remaining two patients with cellulitis.
Therefore, the toad ointment has the functions of treating carbuncle-abscess, pyogenic infections, furunculosis, scrofula and common small sores and furuncles, and has the effect of shortening the treatment time.
The invention has been described in an illustrative manner, and it is to be understood that any simple variations, modifications or other equivalent changes which can be made by one skilled in the art without departing from the spirit of the invention fall within the scope of the invention.
Claims (10)
1. The toad paste is characterized by being prepared from 300-500 parts by mass of de-heading toads, 30-50 parts by mass of frankincense, 30-50 parts by mass of costustoot, 10-30 parts by mass of cassia bark, 20-40 parts by mass of cinnamon leaf, 10-20 parts by mass of iron vine, 10-20 parts by mass of raw kusnezoff monkshood root, 1-3 parts by mass of radix angelicae pubescentis, 6-10 parts by mass of galangal, 1-3 parts by mass of sargassum, 10-20 parts by mass of Chinese angelica, 10-15 parts by mass of radix stephaniae tetrandrae, 10-20 parts by mass of garden balsam stem, 15-25 parts by mass of myrrh, 1-3 parts by mass of menthol, 5-10 parts by mass of safflower and 1-5 parts by mass of raw radix aconiti.
2. The toad paste according to claim 1, wherein the de-heading toad is 300 to 400 parts by mass, the frankincense is 45 to 50 parts by mass, the costus root is 30 to 35 parts by mass, the cinnamon is 25 to 30 parts by mass, the cinnamon leaves are 25 to 29 parts by mass, the iron vine is 10 to 13 parts by mass, the raw kusnezoff monkshood root is 10 to 13 parts by mass, the pubescent angelica root is 1 to 3 parts by mass, the galangal is 6 to 7 parts by mass, the illicium henryi is 1 to 3 parts by mass, the angelica sinensis is 10 to 13 parts by mass, the tetrandra root is 10 to 11 parts by mass, the garden balsam stem is 10 to 13 parts by mass, the myrrh is 15 to 19 parts by mass, the menthol is 1 to 2 parts by mass, the safflower is 5 to 7 parts by mass, and the raw aconite root is 1 to 3 parts by mass.
3. The toad paste according to claim 1, wherein the head-removing toad is 400-450 parts by mass, the frankincense is 40-45 parts by mass, the costus root is 35-45 parts by mass, the cinnamon is 15-25 parts by mass, the cinnamon leaves are 27-32 parts by mass, the iron vine is 14-18 parts by mass, the raw kusnezoff monkshood root is 14-16 parts by mass, the pubescent angelica root is 1-3 parts by mass, the galangal is 8-9 parts by mass, the illicium henryi is 1-3 parts by mass, the angelica sinensis is 14-16 parts by mass, the tetrandra root is 12-13 parts by mass, the garden balsam stem is 14-16 parts by mass, the myrrh is 16-23 parts by mass, the menthol is 1-1.5 parts by mass, the safflower is 5-8 parts by mass, and the raw aconite root is 2-4 parts by mass.
4. The toad paste according to claim 1, wherein the head-removing toad is 400-500 parts by mass, the frankincense is 30-44 parts by mass, the costus root is 45-50 parts by mass, the cinnamon is 10-15 parts by mass, the cinnamon leaves are 33-40 parts by mass, the iron vine is 19-20 parts by mass, the raw kusnezoff monkshood root is 17-20 parts by mass, the pubescent angelica root is 1-3 parts by mass, the galangal is 9-10 parts by mass, the illicium henryi is 1-3 parts by mass, the angelica sinensis is 17-20 parts by mass, the tetrandra root is 13-15 parts by mass, the garden balsam stem is 17-20 parts by mass, the myrrh is 20-25 parts by mass, the menthol is 1-1.5 parts by mass, the safflower is 9-10 parts by mass, and the raw aconite root is 4-5 parts by mass.
5. A method for preparing a toad paste according to any one of claims 1 to 4, comprising the steps of:
1) removing the skin and viscera of the de-heading toad, and drying at 60-80 ℃ for at least 24 hours to obtain dried toads;
2) mechanically pulverizing the dried toad, frankincense, costustoot, cassia bark, cinnamon leaves, iron vines, raw kusnezoff monkshood roots, radix angelicae pubescentis, galangal, illicium japonicum, angelica sinensis, radix stephaniae tetrandrae, garden balsam stems, myrrh, menthol, safflower and raw radix aconiti, sieving with a 50-100-mesh sieve, putting into 400-900 parts by mass of water, preserving heat at 100 ℃ for 0.5-1 hour, and filtering to obtain an extracting solution;
3) heating and concentrating the extracting solution to obtain an extract with the relative density of 1.2-1.3;
4) and uniformly mixing the extract with glycerol, and heating at 30-70 ℃ for 1-4 hours to obtain the toad paste, wherein the ratio of the extract to the glycerol is 1: (0.4-1.2).
6. The preparation method according to claim 5, wherein in the step 1), the drying temperature is 65-75 ℃;
in the step 1), the drying time is 24-36 hours.
7. The production method according to claim 6, wherein in the step 2), the amount of the water is 500 to 800 parts by mass, preferably 600 to 700 parts by mass.
8. The preparation method according to claim 7, wherein in the step 4), the extract is uniformly mixed with glycerin and heated at 40-50 ℃ for 1-2 hours;
in the step 4), the ratio of the extract to the glycerin is 1: (0.6-1).
9. The use method of the toad ointment as claimed in claim 1, wherein the toad ointment is applied to the wound surface, the thickness of the toad ointment is 2-5 mm, and the wound surface is covered with gauze and kept for 24 hours.
10. The use method of claim 9, wherein the use is continuously carried out for 5-12 days for 24 hours each time.
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| CN1351880A (en) * | 2001-11-06 | 2002-06-05 | 李东升 | Pus drawing out paste for expelling wind and removing obstruction in channels and its preparing method |
| CN1457804A (en) * | 2002-05-13 | 2003-11-26 | 马明泽 | Adhesive plaster for curing lymph disease, red wound and lump furuncle |
| CN101623345A (en) * | 2008-07-08 | 2010-01-13 | 韩俊峰 | Chinese medicinal composition for treating scleredema neonatorum |
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