CN111089819B - Blood detection method for prejudging and detecting working state of pump based on hemorheology instrument - Google Patents
Blood detection method for prejudging and detecting working state of pump based on hemorheology instrument Download PDFInfo
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- CN111089819B CN111089819B CN201911302700.5A CN201911302700A CN111089819B CN 111089819 B CN111089819 B CN 111089819B CN 201911302700 A CN201911302700 A CN 201911302700A CN 111089819 B CN111089819 B CN 111089819B
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
- G01N11/08—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by measuring pressure required to produce a known flow
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B51/00—Testing machines, pumps, or pumping installations
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Abstract
The invention relates to the technical field of blood detection, in particular to a blood detection method based on prejudging detection of the working states of pumps of a hemorheology meter, which is used for detecting the working states of all pumps in the hemorheology meter to be detected, and detecting samples by adopting the hemorheology meter to be detected if the working states of all pumps are normal; and (3) closing other pumps except the pump to be tested, starting the pump to be tested to enable the pump to be tested to idle, acquiring N1 fluid pressure data in a pressure bin of the hemorheology meter to be tested in a preset period T1, performing quadratic polynomial fitting on the N1 fluid pressure data by a computer to form a first pressure curve segment P (T), deriving the first pressure curve segment P (T) to obtain a first pressure change curve segment P '(T), and if the first pressure change curve segment P' (T) is in a preset normal region, enabling the rotating speed of the pump to be tested to be normal, reducing the probability of inaccurate detection results caused by equipment problems, reducing the probability of misdiagnosis caused by equipment problems of the hemorheology meter in hospitals, and enabling the whole detection efficiency to be faster and more convenient.
Description
Technical Field
The invention relates to the technical field of blood detection, in particular to a blood detection method based on pump working state pre-judging detection of a hemorheology meter.
Background
The blood rheometer is a blood clinical detecting instrument developed on the basis of the theory of blood rheology, and is a special detecting instrument for early diagnosis of diseases by detecting the viscosity of human blood. In clinic, the occurrence of many diseases is closely related to the change of blood characteristics, the etiology and pathogenesis of the diseases are discussed from the viewpoint of hemorheology, and new diagnosis methods and prevention and treatment measures are provided, so that the method has extremely important significance for preventing and treating the diseases. Therefore, the blood rheology detection is an important detection means for cardiovascular and cerebrovascular diseases and a necessary item for middle-aged and elderly physical examination, and is widely used in large and medium-sized hospitals in various places. Devices for blood rheology detection currently include cone bowl type and electronic-pressure sensing type test devices, electronic-pressure sensing rheometers, which measure blood viscosity mainly by capillary methods. In a specific test process, blood is placed in a closed pipeline, the flow pressure change of the blood in the pipeline is controlled by a pump and an electromagnetic valve to be measured, and the rotation precision of the pump and the control precision of the electromagnetic valve have great influence on the detection precision.
The existing pump in the blood rheometer is difficult to detect after the occurrence of the problem, and only after the detection result is wrong, the blood rheometer is determined to have the problem, and then each pump is detached one by one to be detected independently so as to determine whether each pump operates normally.
Disclosure of Invention
Aiming at the problems that the detection result is wrong but not known and the hospital misdiagnosis is caused by normal operation after the current hemorheology instrument is in trouble and overhauled, the invention provides a blood detection method based on the pre-judging detection of the working state of a pump of the hemorheology instrument, wherein the pump of the hemorheology instrument idles before each test, and the pressure curve generated by judging the idling is compared with the pressure curve of the pump in normal operation, so that whether the pump in the hemorheology instrument works normally or not is judged in advance, the problem of the hemorheology instrument is found before the detection as much as possible, and the probability of inaccurate detection result caused by equipment problem is reduced.
The pressure curves of the pumps of the current hemorheology instrument after being independently started are similar to quadratic curves, so that the real-time quadratic curves of the pumps can be compared with the quadratic curves of normal pumps to judge whether the pumps work normally, and in particular, in order to achieve the purposes of the invention, the invention provides the following technical scheme:
the method comprises the steps of detecting the working states of all pumps in the to-be-detected hemorheology instrument based on a blood detection method for prejudging and detecting the working states of the pumps of the hemorheology instrument, and detecting samples by the to-be-detected hemorheology instrument if the working states of all pumps are normal; detecting the working state of the pump: the method comprises the steps that a pressure bin of a to-be-measured hemorheology meter is communicated with a channel where the to-be-measured pump is located, other channels of the pressure bin are closed, other pumps except the to-be-measured pump are closed, the to-be-measured pump is started to enable the to-be-measured pump to idle, N1 pieces of fluid pressure data in the pressure bin of the to-be-measured hemorheology meter are obtained in a preset period T1, a computer is used for carrying out quadratic polynomial fitting on the N1 pieces of fluid pressure data to form a first pressure curve segment P (T), the first pressure curve segment P (T) is derived to obtain a first pressure change curve segment P '(T), and if the first pressure change curve segment P' (T) is in a preset normal area, the rotating speed of the to-be-measured pump is normal.
Preferably, the starting timing time of the preset period T1 is a start time of the pump to be measured, and a time period from the start of the pump to be measured to the first time that the fluid pressure in the pressure bin of the hemorheology meter to be measured reaches the peak value is Tm, where T1 is less than Tm.
Preferably, T1 is 1.ltoreq.T1 is 2.5s.
Preferably, the time intervals of the N1 fluid pressure data acquisition are the same; the pump to be measured is communicated with the pressure bin of the hemorheology meter to be measured, and other pumps communicated with the pressure bin of the hemorheology meter to be measured are closed; and after the detection of the pump to be detected is finished, replacing other pumps to detect, wherein the other pumps become the pumps to be detected until all the pumps are detected.
Preferably, a pressure bin of the normal hemorheology instrument is communicated with a channel where a normal pump is located, the communication between the pressure bin of the normal hemorheology instrument and other channels is closed, other pumps except the normal pump are closed, the normal pump is started to enable the normal pump to idle, in the pressure bin of the normal hemorheology instrument, N2 fluid pressure data in the pressure bin of the normal hemorheology instrument are obtained in a preset period T2, a computer is used for carrying out quadratic polynomial fitting on the N2 fluid pressure data to form a second pressure curve segment Pm (T), and the second pressure curve segment Pm (T) is derived to obtain a second pressure curve segment Pm' (T), and T2 is less than or equal to T1;
the method is adopted to obtain M second press-transformation curve segments Pm '(T), M is more than or equal to 50, a computer is adopted to calculate the minimum value and the maximum value of the M press-transformation curve segments P1' (T) at each moment in the preset time period T2 in the same coordinate system, the connecting line of the minimum value at each moment forms the lower boundary of the preset normal region, and the connecting line of the maximum value at each moment forms the upper boundary of the preset normal region.
Preferably, R first pressure curve segments P (t) of the pump to be tested are obtained at different moments, and if one of the R first pressure curve segments P (t) is in a preset normal region, the rotation speed of the pump to be tested is normal, and R is greater than or equal to 3.
Preferably, if the first pressure-variable curve segment P '(T) intersects with an upper boundary and the rotation speed of the pump to be measured is normal, calculating that the first pressure-variable curve segment P' (T) and the upper boundary are in the same coordinate system by adopting a computer, and forming a new upper boundary of the preset normal region by connecting a maximum value at each moment within the preset period T2; if the first pressure change curve segment P '(T) intersects with the lower boundary and the rotation speed of the pump to be measured is normal, calculating that the first pressure change curve segment P' (T) and the lower boundary are in the same coordinate system by adopting a computer, and forming a new lower boundary of the preset normal region by connecting a minimum value at each moment within the preset period T2.
Preferably, the second pressure change curve segments Pm' (t) of S normal pumps are obtained, S being greater than or equal to 10.
Compared with the prior art, the invention has the beneficial effects that: the working state of each pump can be detected without disassembling the pump before detecting a sample, so that whether the pump in the hemorheometer works normally or not is judged in advance, the problem of the hemorheometer is found before detection as far as possible, the probability of inaccurate detection results caused by equipment problems is reduced, and the probability of misdiagnosis caused by the equipment problems of the hemorheometer in hospitals is reduced;
in addition, this application only needs to be through gathering pressure data can judge whether the pump normally works, therefore, need not dismantle the pump one by one in order to judge whether the pump normally works, consequently, if blood rheometer testing result is incorrect, can confirm whether the pump normally operates through above-mentioned method, can be more swift convenient, detect whether each pump just can accomplish the detection of all pumps after normal operation one by one, whole detection efficiency is more swift and convenient, and, because pressure sensor itself is the blood rheometer has, consequently also can not increase the volume of whole equipment, in addition, actual pressure sensor itself volume is also less.
Description of the drawings:
FIG. 1 is a schematic view of a portion of an apparatus arrangement of a hemorheology meter;
FIGS. 2 and 3 are schematic diagrams of a preset normal range determination method of the present application;
the marks in the figure: 110-pressure bin, 121-first pump, 122-second pump, 131-first solenoid valve, 132-second solenoid valve, 133-third solenoid valve, 141-first pressure sensor, 142-second pressure sensor.
Detailed Description
The present invention will be described in further detail with reference to test examples and specific embodiments. It should not be construed that the scope of the above subject matter of the present invention is limited to the following embodiments, and all techniques realized based on the present invention are within the scope of the present invention.
The working state of each pump in the hemorheology instrument to be detected is detected, if the working state of each pump is normal, the hemorheology instrument to be detected is adopted to detect the sample, and if the working state of the pump is not normal, prompt information is sent to overhaul equipment.
Specifically, as shown in fig. 1, when detecting the working state of the pump, the first electromagnetic valve and the second electromagnetic valve are closed, the third electromagnetic valve is opened, the second pump is stopped, the first pump is started as the pump to be detected to pump air into the pressure bin, and the second pressure sensor is used for collecting and detecting the pressure data required by the pump to be detected, so that the whole process is ensured: the pressure bin of the hemorheology instrument to be measured is only communicated with the channel where the pump to be measured is located, but not communicated with other channels, and other pumps except the pump to be measured are closed; the first solenoid valve is closed to avoid aspirating the sample during testing.
The system also comprises a controller and a display, wherein the controller is connected with the first pressure sensor and the second pressure sensor to acquire data for analyzing the first pressure sensor and the second pressure sensor, and the controller is connected with the display to display analysis results on the display.
When the working state of the pump to be tested is detected, the pump to be tested is started to idle, a second pressure sensor acquires N1 fluid pressure data in a pressure bin of the hemorheology meter to be tested in a preset period T1, the interval time for acquiring the pressure data is the same, a controller carries out quadratic polynomial fitting on the N1 fluid pressure data by taking time as a horizontal axis pressure value as a vertical axis to form a first pressure curve segment P (T) (0.ltoreq.t.ltoreq.T1), the first pressure curve segment P (T) (0.ltoreq.t.t1) is derived to obtain a first pressure curve segment P '(T) (0.ltoreq.tT 1), the controller judges whether the first pressure curve segment P' (T) is in a preset normal region or not, if so, the rotating speed of the pump to be tested is normal, and displaying the normal prompt information of the pump to be tested on the display, thereby judging whether the first pump serving as the pump to be tested is normally operated, taking the second pump as the pump to be tested after the first pump is detected, specifically, closing the first electromagnetic valve and the third electromagnetic valve, opening the second electromagnetic valve, stopping the first pump, starting the second pump as the pump to be tested, pumping air into the pressure bin, determining whether the second pump serving as the pump to be tested is normally operated according to the method, integrally closing the passages of other pumps, and starting only the passages of the pumps to be tested to detect whether the pumps to be tested are normally operated, so that whether the pumps are normally operated can be checked one by one.
The idling of the above scheme is that the pump to be tested runs under the condition of partially sucking the sample, and the air in the sucking mode and the idling mode of the pump to be tested are two, one is that the pump to be tested rotates to suck external air into the pressure bin of the hemorheology meter to be tested, so that the pressure in the pressure bin of the hemorheology meter to be tested is increased, and the other is that the pump to be tested rotates to suck the air in the pressure bin of the hemorheology meter to be tested to be discharged to the outside, so that the pressure in the pressure bin of the hemorheology meter to be tested is reduced.
The curve of the pressure change in the pressure bin before the pressure is stabilized is similar to a quadratic curve during the normal operation of the pump, and the scheme detects the pressure in the process of rising or falling the pressure, so that the pressure data of the pressure bin can be obtained before the pressure reaches the first wave crest or the first wave trough, and the data is actually obtained before the pressure data is stabilized to ensure that the quadratic curve formed by fitting is more similar to the real curve, specifically, the starting timing time of the preset period T1 is the starting time of the pump to be tested, and the time period from the starting of the pump to be tested to the time when the fluid pressure in the pressure bin of the hemorheometer to be tested reaches the wave peak value for the first time is T m ，T1＜T m The method comprises the steps of carrying out a first treatment on the surface of the Or the starting timing time of the preset period T1 is the time when the pump to be measured rotates to suck the fluid in the pressure bin of the hemorheology meter to be measured, and the time period from the start of the rotation of the pump to be measured to the time when the fluid pressure in the pressure bin of the hemorheology meter to be measured reaches the trough value for the first time is T m ，T1＜T m Preferably 1.5 s.ltoreq.T1.ltoreq.2.5 s, and in particular T1 may be 1.5s, 1.7s, 1.9s, 2.1s, 2.3s or 2.5s.
The preset normal area in the above scheme can be determined in the following manner:
the pressure bin of the normal hemorheology instrument is communicated with a channel where one normal pump is located, the communication between the pressure bin of the normal hemorheology instrument and other channels is closed, other pumps except the normal pump are closed, the normal pump is started to enable the normal pump to idle, in the pressure bin of the normal hemorheology instrument, N2 fluid pressure data in the pressure bin of the normal hemorheology instrument are obtained in a preset period T2, the interval time for obtaining the pressure data is the same, and the controller carries out quadratic polynomial fitting on the N2 fluid pressure data by adopting a computer with the time as a horizontal axis pressure value and a vertical axis to form a second pressure curve segment P m (T) (0.ltoreq.t.ltoreq.T2) and for the second pressure curve segment P m (t) deriving to obtain a second pressure-change curve segment P m 'T' (T is more than or equal to 0 and less than or equal to T2), and T2 is more than or equal to T1; the method is adopted to obtain M second press-transformation curve segments P m 'T' (T is more than or equal to 0 and less than or equal to T2), M is more than or equal to 50, and a computer is adopted to calculate M pressure change curve sections P 1 'T' (T is more than or equal to 0 and less than or equal to T2) in the same coordinate system, wherein the minimum value and the maximum value of each moment in the preset period T2 are connected, the connecting line of the minimum value of each moment forms the lower boundary of the preset normal region, and the connecting line of the maximum value of each moment forms the upper boundary of the preset normal region;
referring specifically to fig. 2 and 3, as shown in fig. 2, seven second press-to-change curve segments P are illustrated m 'T' (0.ltoreq.t.ltoreq.T2) b1, b2, b3, b4, c1, c2 and c3, respectively, M second pressure-variable curve segments P m The line segment near the edge in' (t) and the line segment in the middle region are not shown, and in FIG. 2, C2 and C3 intersect at the time TS1, and at the time 0.ltoreq.t.ltoreq.TS 1 periodIn M second press-changing curve segments P m The maximum connecting line of' (T) is C3 curve segment, and M second pressure change curve segments P are in the period of TS1 < t.ltoreq.T2 m The maximum value connecting line of the' (T) is a C2 curve segment, so that the combination of the C3 curve segment in the time period of 0-T-T1 and the C2 curve segment in the time period of TS 1-T-T2 forms the upper boundary of a preset normal area;
similarly, the b2 curve segment and the b4 curve segment intersect at the moment TS2, and M second press-changing curve segments P are arranged in the period of TS2 < T < T2 m The minimum connecting line of' (t) is the b4 curve segment, so that M second pressure change curve segments P are arranged in the period of 0.ltoreq.t.ltoreq.TS 2 m A part of the minimum value connection line of the (t) is a b1 curve segment, and the other part is a b2 curve segment, so that a lower boundary of a preset normal region exists, specifically as shown in fig. 3, a region between the upper boundary and the lower boundary is the preset normal region, that is, a cross-sectional region in fig. 3.
The idling of the normal pump is the same as the idling of the pump to be tested, and two conditions exist, namely, the pressure data are acquired in the pressure reduction process of the pressure bin of the normal hemorheology meter to determine a preset normal area, the pressure data are acquired in the pressure increase process of the pressure bin of the normal hemorheology meter to determine a preset normal area, the preset normal areas determined in the two modes are different, however, the preset normal area determined in the pressure increase process can only be used for testing the pump to be tested under the pressure increase condition of the pressure bin, and the preset normal area determined in the pressure decrease process can only be used for testing the pump to be tested under the pressure decrease condition of the pressure bin, so that the two conditions cannot be mixed.
In addition, the larger the values of W and M, the more accurately the preset normal region is determined, the higher the inspection accuracy of the pump operating state, preferably W and M are equal to 100, 200, 400, 600, 800, 1000, 1500, 2000 or 5000.
Although the parameters of the pumps with the same specification are required to be the same, no two pumps are completely identical due to factors such as actual machining error assembly error, and if only one normal pump is adopted to determine the preset normal area, the accuracy of the preset correct area is lower, so that the detection accuracy is further improvedIn the above scheme for determining the normal preset area, the second pressure-change curve segments P of the S normal pumps are obtained m ' (t), preferably, each normal pump acquires M second pressure-change curve segments P m ' t, then a total of S times M second pressure change curve segments P m ' t, in both scheme one and scheme three, S is multiplied by M second press-change curve segments P m 't' replacing M second variable curve segments P m The proposal of (t) can ensure that the preset normal region is determined more accurately, so that the detection result is more accurate, S is more than or equal to 10, and is preferably 20, 40, 60, 80, 100, 200, 400, 800 or 1000.
Preferably, to further improve the detection accuracy, if the first pressure-variable curve segment P '(T) intersects with an upper boundary and the rotation speed of the pump to be detected is normal, calculating that the first pressure-variable curve segment P' (T) and the upper boundary are in the same coordinate system by adopting a computer, and forming a new upper boundary of the preset normal region by connecting a maximum value at each moment within the preset period T2; if the first pressure change curve segment P '(T) intersects with the lower boundary and the rotation speed of the pump to be measured is normal, calculating that the first pressure change curve segment P' (T) and the lower boundary are in the same coordinate system by adopting a computer, and forming a new lower boundary of the preset normal region by connecting a minimum value at each moment within the preset period T2.
The above-mentioned schemes all test under the condition that other required conditions all meet, such as fluid is sufficient, but there is some problem that causes the parameter to temporarily suddenly distort in the course of actual operation, will cause the error at this moment, therefore, obtain R pieces of first pressure curve section P (t) of the pump to be measured at different moments, if one of said R pieces of first pressure curve section P (t) is in the normal area of presetting, then the rotational speed of the pump to be measured is normal, R is greater than or equal to 3, therefore, detect more accurately.
Claims (6)
1. The blood detection method based on the pre-judging detection of the working states of the pumps of the hemorheology instrument is characterized by detecting the working states of the pumps in the hemorheology instrument to be detected, and if the working states of the pumps are all normal, the hemorheology instrument to be detected is adopted to detect the sample;
detecting the working state of the pump: the method comprises the steps that a pressure bin of a to-be-measured hemorheology meter is communicated with a channel where the to-be-measured pump is located, other channels of the pressure bin are closed, other pumps except the to-be-measured pump are closed, the to-be-measured pump is started to enable the to-be-measured pump to idle, N1 pieces of fluid pressure data in the pressure bin of the to-be-measured hemorheology meter are obtained in a preset period T1, a computer is used for carrying out quadratic polynomial fitting on the N1 pieces of fluid pressure data to form a first pressure curve segment P (T), the first pressure curve segment P (T) is derived to obtain a first pressure curve segment P '(T), and if the first pressure curve segment P' (T) is in a preset normal area, the rotating speed of the to-be-measured pump is normal;
the pressure bin of the normal hemorheology instrument is communicated with a channel where the normal pump is located, the communication between the pressure bin of the normal hemorheology instrument and other channels is closed, other pumps except the normal pump are closed, the normal pump is started to enable the normal pump to idle, N2 fluid pressure data in the pressure bin of the normal hemorheology instrument are obtained in a preset period T2 in the pressure bin of the normal hemorheology instrument, and a computer is adopted to perform quadratic polynomial fitting on the N2 fluid pressure data to form a second pressure curve segment P m (t) and for the second pressure curve segment P m (t) deriving to obtain a second pressure-change curve segment P m ’(t)，T2≤T1；
The method is adopted to obtain M second pressure-change curve segments P m 't', M is more than or equal to 50, and the M second pressure change curve segments P are calculated by a computer m ' (T) minimum and maximum values at respective times in the same coordinate system within the preset period T2, and a line of the minimum values at respective times forms a lower boundary of the preset normal region, and a line of the maximum values at respective times forms an upper boundary of the preset normal region.
2. The method for detecting blood based on prejudging detection of working state of a pump of a hemorheology meter according to claim 1, wherein the starting timing time of the preset period T1 is the starting time of the pump to be detected, and the fluid pressure in the pressure bin of the hemorheology meter is from the starting of the pump to be detectedThe time period for reaching the peak value at one time is T m ，T1＜T m 。
3. The method for blood detection based on the pre-judgment detection of the working state of a pump for blood rheology according to claim 2, wherein 1.5 s.ltoreq.T1.ltoreq.2.5 s.
4. The method for detecting the blood based on the pre-judgment detection of the working state of the pump of claim 1, wherein the time intervals of the N1 fluid pressure data acquisition are the same; the pump to be measured is communicated with the pressure bin of the hemorheology meter to be measured, and other pumps communicated with the pressure bin of the hemorheology meter to be measured are closed; and after the detection of the pump to be detected is finished, replacing other pumps to detect, wherein the other pumps become the pumps to be detected until all the pumps are detected.
5. The blood detection method based on the pre-judging detection of the working state of the pump of claim 1, wherein if the first pressure-change curve segment P '(T) intersects with an upper boundary and the rotation speed of the pump to be detected is normal, calculating that the first pressure-change curve segment P' (T) and the upper boundary are in the same coordinate system by adopting a computer, and forming a new upper boundary of the preset normal region by connecting a maximum value at each moment in the preset period T2; if the first pressure change curve segment P '(T) intersects with the lower boundary and the rotation speed of the pump to be measured is normal, calculating that the first pressure change curve segment P' (T) and the lower boundary are in the same coordinate system by adopting a computer, and forming a new lower boundary of the preset normal region by connecting a minimum value at each moment within the preset period T2.
6. The blood test method based on the pre-judgment and detection of the operation state of the pump of the hemorheology meter according to claim 1, characterized in that the second pressure-change curve segments P of the S normal pumps are obtained m ' (t), S is greater than or equal to 10.
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| ATE389807T1 (en) * | 2004-02-11 | 2008-04-15 | Grundfos As | METHOD FOR DETERMINING ERRORS DURING THE OPERATION OF A PUMP UNIT |
| JP4369321B2 (en) * | 2004-07-30 | 2009-11-18 | 株式会社高田工業所 | Diagnosis method of fluid rotating machine |
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| JP6362008B2 (en) * | 2015-02-09 | 2018-07-25 | Smc株式会社 | Pump system and pump abnormality detection method |
| CN106075680B (en) * | 2016-05-27 | 2018-07-06 | 湖南明康中锦医疗科技发展有限公司 | A kind of detection method and device of turbofan qualification |
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