CN111012312B - Portable parkinsonism bradykinesia monitoring and intervention device and method - Google Patents
Portable parkinsonism bradykinesia monitoring and intervention device and method Download PDFInfo
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Abstract
The invention provides a portable device and a method for monitoring and intervening motor retardation of parkinsonism. The wearable intelligent device consists of a wearable inertial node and an intelligent bracelet, wherein an inertial sensor is used for collecting motion data of a patient and transmitting the motion data to the intelligent interaction device through the intelligent bracelet integrated motion information data, the intelligent interaction device collects data of an interaction task completed by a user, extracts characteristic values from all the data and inputs the characteristic values into an evaluation model for evaluation analysis, an evaluation result is obtained and displayed, the motion intervention device performs action intervention correction on an 'intervention' state, and the intelligent interaction device further transmits the evaluation result to an information recording device through a network connection device so as to record and store the staged monitoring result in a database in combination with personal information of the user. The invention can be applied to the symptom monitoring and curative effect evaluation of the Parkinson patients.
Description
Technical Field
The invention relates to the fields of sensing technology, biomedical engineering, rehabilitation equipment and medical and health, in particular to a portable device and a method for monitoring and intervening motor retardation of parkinsonism.
Background
Parkinson's disease is a common nervous system degenerative disease, is not easy to detect in the early stage of the disease, has high misdiagnosis rate, and can seriously influence the life of patients in the late stage. Bradykinesia, tremor, muscle rigidity and postural instability are considered to be the most significant clinical features of parkinson's disease, and are one of the requisite symptoms for clinical diagnosis, as well as important factors affecting the quality of life of patients. Bradykinesia is often defined as a decrease in the speed, frequency and amplitude of repetitive motion, including voluntary movements, with major impairment in terms of speed and amplitude, such as during straight-through travel, where rapid and steady pace is not guaranteed. Meanwhile, several documents indicate that for the detection of bradykinesia, a stronger predictor is on the upper limb.
At present, most of clinical evaluation of bradykinesia symptoms is based on scales, and objective quantitative evaluation means are few and not widely popularized, so that judgment of severity of bradykinesia depends on clinical experience of doctors, and the subjective defect exists, and meanwhile, the method has great difficulty in realizing an immediate feedback monitoring intervention system for patients.
For this reason, chinese patent publication No. CN 108664147a, entitled "a quantitative detection device and detection method for bradykinesia and tremors" discloses a quantitative detection device for bradykinesia of parkinson's disease patients, which comprises a writing input module, a data acquisition module, and a data analysis module, wherein fine pen data input by a subject through an electronic handwriting pen is captured and analyzed in a deep learning and big data manner, and handwriting data characteristics of the subject are obtained, so as to quantify the bradykinesia degree of the subject.
The device for quantitatively detecting the motor retardation of the parkinsonism can detect the motor retardation of the patient, but the disclosed device does not subdivide the motor state interval of the user in a static waiting task, and errors are inevitably introduced.
Disclosure of Invention
The invention aims to solve the technical problems that: the device provides an independently-operable bradykinesia monitoring intervention device for patients, and simultaneously realizes automatic bradykinesia detection based on a portable device on the premise of not affecting the daily activities of patients with parkinsonism and reducing physical constraints, and has higher sensitivity and specificity.
In order to solve the technical problems, the invention provides a portable monitoring and intervention device for parkinsonism, which is characterized in that: the intelligent interaction device comprises wearable intelligent equipment, intelligent interaction equipment, sports intervention equipment, network connection equipment and information recording equipment;
the wearable intelligent device consists of a wearable inertial node worn in the middle section of an index finger and an intelligent bracelet worn on the wrist; the wearable inertia node is used for collecting finger movement data of a user and transmitting the finger movement data to the intelligent bracelet; the intelligent bracelet is used for acquiring wrist movement data, synchronizing and integrating finger movement information data, and transmitting the data to the intelligent interaction equipment;
the intelligent interaction equipment provides data management, result evaluation and intervention instruction issuing; the intelligent interaction equipment is used for collecting interaction motion data of users in interaction tasks, extracting characteristic values from all the motion data and inputting an evaluation model for evaluation analysis, and obtaining and displaying evaluation results; in addition, the method is also used for sending the evaluation result to the information recording device through the network connection device; meanwhile, comparing the evaluation result with a preset threshold value, judging whether the state is an 'intervention-needed' state, and sending an exercise intervention instruction under the basis of the machine selection;
the motion intervention device performs motion intervention correction on the 'corresponding intervention' state according to the evaluation result, and the intelligent interaction device is used for sending the evaluation result to the information recording device through the network connection device; the information recording equipment is used for storing the staged monitoring evaluation result into the database;
the wearable inertial node comprises a first inertial sensor, a first data storage module, a first Bluetooth communication module, a first microcontroller, a first power management module, a first battery and a first data interface; the intelligent bracelet comprises a second inertial sensor, a second data storage module, a second Bluetooth communication module, a second microcontroller, a second power management module, a second battery and a second data interface;
the first inertial sensor is independently worn and is used for collecting acceleration data, angular velocity data and magnetic field intensity data;
the first data storage module is used for storing data acquired by the first inertial sensor;
the first Bluetooth communication module is used for transmitting the data detected by the first inertial sensor to the intelligent bracelet;
the first microcontroller is used for controlling the first inertial sensor to collect data and controlling the first Bluetooth communication module to interact data and instructions with the intelligent bracelet;
the first power management module is used for carrying out power management on the first inertial sensor and guaranteeing normal power supply and stable battery endurance time;
the first battery supplies power to the first inertial sensor;
the first data interface is used for charging and data wired downloading;
the second inertial sensor is embedded and can be embedded into the intelligent bracelet and used for collecting acceleration data, angular velocity data and magnetic field intensity data;
the second data storage module is used for storing data acquired by the second inertial sensor;
the second Bluetooth communication module is used for carrying out Bluetooth communication with the wearable inertial node to obtain data and sending the regular motion information data to the intelligent interaction device;
the second microcontroller is used for controlling the second inertial sensor to acquire data and controlling the second inertial sensor to perform data synchronization and integration with the wearable inertial node, and controlling the second Bluetooth communication module to perform data and instruction interaction with the intelligent bracelet and the intelligent interaction device;
the second power management module is used for carrying out power management on the intelligent bracelet, so that normal power supply and stable battery endurance time are ensured;
the second battery supplies power for the intelligent bracelet;
the second data interface is used for charging and data wired downloading;
the first data interface and the second data interface have the same structure and are sealed by a detachable waterproof rubber cover;
the exercise intervention device is a Bluetooth earphone, is connected with the intelligent interaction device in a Bluetooth mode, and receives a feedback signal of the intelligent interaction device to execute an exercise correction intervention task;
the intelligent interaction device is used for providing data management, evaluation results and intervention instruction issuing for patients.
The wearable inertia node is fixed by a plastic element, and the plastic element is a ring-shaped element made of elastic memory material and is used for fixing the wearable inertia node to an index finger;
the wearable inertial node is miniature, has small mass and has an attaching area not more than 0.8cm 2 The mass is not more than 3g, so that the intervention on the movement of a user can be reduced as much as possible;
the intelligent bracelet is multifunctional, and comprises the steps of collecting wrist movement data of a user by means of an embedded inertial sensor of the intelligent bracelet, synchronizing finger movement data collected by the intelligent bracelet and a wearable inertial node at an index finger, and performing data and instruction interaction with the intelligent interaction device.
The intelligent interaction device is an electronic device which is provided with a high-definition display screen and has network communication capability, and comprises a touch screen notebook computer, a tablet computer or a smart phone, and can acquire and process data when a patient executes an interaction task; running interactive software on the intelligent interactive equipment; the interactive software guides the user to log in by a personal mode, and further provides monitoring mode selection, interactive task execution and evaluation result display functions for the user; the monitoring mode selection is provided for different monitoring scene selections of a user, such as unconstrained regular monitoring or silence monitoring when the monitoring is inconvenient temporarily, and the intelligent interaction device executes different monitoring activities corresponding to different monitoring modes; the intelligent interaction device guides a user to conduct interaction tasks of handwriting trace copying, repeated writing of characters with strong continuity, fine movement reaction and nerve sensitivity reaction such as a mouse playing game; the evaluation result display is that the motion monitoring performance of the user is displayed in the interactive software display frame in real time, and in addition, when the monitoring is finished, the interactive software displays a monitoring report sheet of the whole monitoring process;
the sports intervention device, namely the Bluetooth headset, can give out audio prompt signals with different intensities and durations under the condition of occurrence of different degrees of sports retardation.
The working method comprises the following steps:
step 301: opening a wearable inertia node and an intelligent bracelet;
step 302: starting intelligent interaction equipment and starting interaction software, initializing operation, and starting and connecting a Bluetooth headset;
step 303: inputting basic information of a patient in interactive software, wherein the basic information comprises information such as name, gender, age, weight, illness time and the like;
step 304: in the interactive software, clicking a connection inertia node, clicking a calibration button, clicking a connection Bluetooth headset, and clicking an initialization button;
step 305: inputting relevant configuration information of the information recording equipment in the interactive software, and clicking connection;
step 306: the wearable inertial node of the device on the plastic element is fixed at the front position of the middle end of the index finger of a user, the front end of the fixed position is provided with a finger part enough for executing interaction tasks, and the user wears an intelligent bracelet and a Bluetooth headset;
step 307: clicking a conventional monitoring button in interactive software;
step 308: the intelligent interaction equipment gives out an interaction task, a display screen shows task guidance, finger kneading, gripping actions, handwriting track copying and strong-consistency character copying tasks randomly appear, and in the task execution process, the intelligent interaction equipment judges whether the specific task execution quality is qualified or not, data are collected if the specific task execution quality is qualified, and the data are discarded if the specific task execution quality is unqualified;
step 309: in the working process, the intelligent interaction equipment extracts relevant characteristic values of bradykinesia according to all the motion data acquired by the intelligent interaction equipment and the wearable intelligent equipment, and then carries out classification quantitative detection evaluation according to the characteristic values to obtain an evaluation result and displays the evaluation result;
step 310: when the monitoring score reaches an 'intervention-needed' state, the intelligent interaction device sends a corresponding exercise correction intervention instruction to the exercise intervention device according to the measurement score, and at the moment, the user receives an audio prompt intervention signal to perform self exercise intervention;
step 311: the intelligent interaction equipment generates a periodic monitoring evaluation report at intervals and sends the periodic monitoring evaluation report to the information recording equipment through the network connection equipment;
step 312: the information recording equipment receives the report and stores the report into a database in combination with personal information of the user;
step 313: the user selects and clicks the buttons of 'continue', 'silence monitor', 'end monitor' in the interactive software, if 'continue' is selected, the step goes to 308, if 'silence monitor' is selected, the wearable inertial node is selectively removed, the interactive task is stopped, the daily activity is changed to be monitored, the step goes to 310, if 'end monitor' is selected, the step goes to 314;
step 314: all inertial sensors stop data acquisition, and the Bluetooth earphone is closed;
step 315: the information recording equipment generates a monitoring report by combining the overall athletic performance with personal information and the past evaluation result, stores the monitoring report in a database and sends the monitoring report to the intelligent interaction equipment by means of the network connection equipment;
step 316: the user obtains a report page for viewing and downloading.
The bradykinesia detection method comprises the following steps:
step 401: selecting a proper window function, and selecting the window length and the step length;
step 402: dividing a window and carrying out Fourier time-frequency domain transformation on acceleration data in the window;
step 403: calculating the total energy of the window according to the power spectrum after Fourier transformation;
step 404: acquiring inertial sensor data time/frequency domain characteristic data, including mean value, standard deviation, skewness, approximate entropy, amplitude and maximum starting speed;
step 405: acquiring patient interactive exercise task performance data, and calculating track tracking stationarity, character copying scale reduction change, pen-up hesitation, task time consumption and accuracy;
step 406: selecting a proper energy threshold and a bradykinesia threshold;
step 407: comparing the total energy in the window to an energy threshold;
step 408: judging whether the patient is in a static waiting state, if so, continuing monitoring, and if not, jumping to the step 409;
step 409: and according to the acquired inertial node data characteristics and the acquired interactive exercise task performance characteristics, carrying out statistical analysis, and comparing with a bradykinesia threshold value to judge whether the exercise is in a bradykinesia state or not.
The invention has the following beneficial effects:
(1) According to the portable parkinsonism bradykinesia monitoring and intervening device, more available features are excavated, the inertial sensor is used for capturing finger pinching and full-hand grasping motion features, the intelligent interaction equipment is used for capturing feature data in track tracking and character copying tasks, the use of complementary features effectively improves detection accuracy, and accordingly, the monitoring effect is effectively improved;
(2) According to the invention, when the characteristics are fused, the total energy of the power spectrum in a specific window is counted by using the acceleration rate of the inertial sensor, and whether a patient is in a static waiting task state is judged, so that misjudgment of bradykinesia symptoms is effectively avoided;
(3) The invention provides a task monitoring intervention mode and a silence monitoring intervention mode. The task monitoring intervention mode is that the intelligent interaction equipment guides a user to complete an interaction task, during which, the bradykinesia symptom is monitored according to the exercise information data, and when the condition of 'intervention' is reached, exercise intervention is carried out through the exercise intervention equipment; the monitoring target of the silence monitoring intervention mode is the daily activities of the user, the wearable inertial node can be selectively removed, during the period, the intelligent bracelet monitors the bradykinesia symptoms according to the daily life exercise data of the user, and exercise intervention is carried out through exercise intervention equipment when the condition of 'should be interfered' is reached;
(4) The wearable inertia node is fixed on the annular plastic element, is convenient to wear, does not have the problems of slipping, poor contact and the like, and ensures the reliability and stability of data;
(5) Compared with the traditional motor retardation detection system, the portable motor retardation monitoring and intervention device provided by the invention has the advantages that the monitoring scores are displayed in real time through the intelligent interaction equipment, the visual effect is provided, and in addition, audio prompt feedback is given to a user through the motor intervention equipment according to the preset threshold value so as to improve the motor performance;
(6) The portable device and the method for monitoring and intervening the parkinsonism can generate detailed monitoring reports, objectively quantify the starting time point, duration and occurrence period of the patient bradykinesia, and can help a professional doctor to objectively evaluate the severity of the patient bradykinesia and give a more objective rehabilitation treatment plan.
Drawings
FIG. 1 is a schematic diagram of a portable parkinsonism bradykinesia monitoring intervention device layout of the present invention; wherein 101 wearable inertial node; 102, an intelligent bracelet; 103 plastic elements; 104, intelligent interaction equipment; 105 network connection devices; 106 an information recording device; 107 a motion intervention device;
FIG. 2 is a schematic diagram of a portable device for monitoring and intervening motor retardation of Parkinson's disease;
FIG. 3 is a schematic diagram of interactive tasks on an intelligent interactive device in a portable device for monitoring and intervening motor retardation of Parkinson's disease according to the present invention;
FIG. 4 is a flowchart of the method of operation of a portable parkinsonism bradykinesia monitoring intervention device of the present invention;
fig. 5 is a flowchart of a method for detecting symptoms of a portable device for monitoring and intervention for parkinsonism.
Detailed Description
The following describes the technical scheme of the present invention in detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the present invention, but are not intended to limit the invention in any way. It should be noted that all other embodiments obtained without inventive effort by a person skilled in the art fall within the scope of protection of the present invention.
As shown in fig. 1 and fig. 2, a schematic layout diagram of a portable device for monitoring and intervening motor retardation of parkinson's disease according to the present invention includes a wearable inertial node 101, a smart bracelet 102, a plastic element 103, a smart interaction device 104, a network connection device 105, an information recording device 106, and a motor intervening device 107. Wherein, wearable inertial node 101 and smart bracelet 102 constitute wearable smart device. The wearable inertia node 101 is fixed on an index finger through a ring-shaped element made of elastic memory materials, and is used for collecting finger movement data of a user and transmitting the finger movement data to the intelligent bracelet 102, the intelligent bracelet 102 is used for collecting wrist movement data, synchronizing and integrating finger movement information data, and is further used for transmitting the data to the intelligent interaction equipment 104, the intelligent interaction equipment 104 is used for collecting interaction movement data of the user in interaction tasks, such as track tracking and repeatedly writing strong consistency characters, meanwhile, characteristic values are extracted from all movement data and are input into an evaluation model for evaluation analysis, evaluation results are obtained and displayed, a Bluetooth headset performs action intervention correction according to the evaluation results, namely audio prompt signals with different intensities and durations are given to different degrees of motion retardation occurrence, in addition, the intelligent interaction equipment 104 is used for transmitting the evaluation results to the information recording equipment 106 through the network connection equipment 105, and the information recording equipment 106 is used for storing staged monitoring evaluation results into a database; in addition, the intelligent interaction device 104 displays the evaluation result, and can generate a quantitative monitoring report according to personal information of the parkinsonism patient and the evaluation result, the information recording device 106 records the monitoring report in a staged manner, a doctor user can check the monitoring report of all patients under name by accessing the information recording device database, and the patient and the family members of the patient can check the monitoring report of the patient, the diagnosis result and advice of the doctor through the intelligent interaction device 104.
The wearable inertial node 101 is miniature and has small mass, and the attaching area is not more than 0.8cm 2 The mass is not more than 3g, so that the intervention on the movement of a user can be reduced as much as possible;
the intelligent bracelet 102 is multifunctional, and comprises the steps of acquiring wrist motion data of a user by means of an embedded inertial sensor thereof, synchronizing the wrist motion data with finger motion data acquired by the wearable inertial node 101 at the index finger, and performing data and instruction interaction with the intelligent interaction device 104;
the intelligent interaction device 104 is an electronic device which is provided with a high-definition display screen and has network communication capability, and comprises a touch screen notebook computer, a tablet computer or a smart phone, and can acquire and process data when a patient executes an interaction task; running interactive software on the intelligent interactive device 104; the interactive software guides the user to log in by a personal mode, and further provides monitoring mode selection, interactive task execution and evaluation result display functions for the user; the monitoring mode selection is provided for different monitoring scene selections of a user, such as unconstrained regular monitoring or silence monitoring when the monitoring is inconvenient temporarily, and the intelligent interaction device executes different monitoring activities corresponding to different monitoring modes; the intelligent interaction device guides a user to conduct interaction tasks of handwriting trace copying, repeated writing of characters with strong continuity, fine movement reaction and nerve sensitivity reaction such as a mouse playing game; the evaluation result display is that the motion monitoring performance of the user is displayed in the interactive software display frame in real time, and in addition, when the monitoring is finished, the interactive software displays a monitoring report sheet of the whole monitoring process;
fig. 3 is a schematic diagram of an interactive task on an intelligent interactive device in the portable device for monitoring and intervening motor retardation of parkinson's disease according to the present invention; 201-206, wherein interaction software irregularly presents a plurality of line segments which are connected with each other in pairs, and prompts a patient to track; 207-210, wherein the four characters are all strong-consistency characters, the software irregularly jumps out of the repeated writing character task, and each character is written at least 4 times; 211-214 are four detection buttons, the interactive software prompts the user to click the randomly lightened button at the fastest speed, the click task is repeated 6 times,
As shown in fig. 4, a flowchart of an operating method of the portable device for monitoring and intervening motor retardation of parkinson's disease according to the present invention is shown, wherein the operating method comprises the steps of:
step 301: opening a wearable inertia node and an intelligent bracelet;
step 302: starting intelligent interaction equipment and starting interaction software, initializing operation, and starting and connecting a Bluetooth headset;
step 303: inputting basic information of a patient in interactive software, wherein the basic information comprises information such as name, gender, age, weight, illness time and the like;
step 304: in the interactive software, clicking a connection inertia node, clicking a calibration button, clicking a connection Bluetooth headset, and clicking an initialization button;
step 305: inputting relevant configuration information of the information recording equipment in the interactive software, and clicking connection;
step 306: the wearable inertial node of the device on the plastic element is fixed at the front position of the middle end of the index finger of a user, the front end of the fixed position is provided with a finger part enough for executing interaction tasks, and the user wears an intelligent bracelet and a Bluetooth headset;
step 307: clicking a conventional monitoring button in interactive software;
step 308: the intelligent interaction equipment gives out an interaction task, a display screen shows task guidance, finger kneading, gripping actions, handwriting track copying and strong-consistency character copying tasks randomly appear, and in the task execution process, the intelligent interaction equipment judges whether the specific task execution quality is qualified or not, data are collected if the specific task execution quality is qualified, and the data are discarded if the specific task execution quality is unqualified;
step 309: in the working process, the intelligent interaction equipment extracts relevant characteristic values of bradykinesia according to all the motion data acquired by the intelligent interaction equipment and the wearable intelligent equipment, and then carries out classification quantitative detection evaluation according to the characteristic values to obtain an evaluation result and displays the evaluation result;
step 310: when the monitoring score reaches an 'intervention-needed' state, the intelligent interaction device sends a corresponding exercise correction intervention instruction to the exercise intervention device according to the measurement score, and at the moment, the user receives an audio prompt intervention signal to perform self exercise intervention;
step 311: the intelligent interaction equipment generates a periodic monitoring evaluation report at intervals and sends the periodic monitoring evaluation report to the information recording equipment through the network connection equipment;
step 312: the information recording equipment receives the report and stores the report into a database in combination with personal information of the user;
step 313: the user selects and clicks the buttons of 'continue', 'silence monitor', 'end monitor' in the interactive software, if 'continue' is selected, the step goes to 308, if 'silence monitor' is selected, the wearable inertial node is selectively removed, the interactive task is stopped, the daily activity is changed to be monitored, the step goes to 310, if 'end monitor' is selected, the step goes to 314;
step 314: all inertial sensors stop data acquisition, and the Bluetooth earphone is closed;
step 315: the information recording equipment generates a monitoring report by combining the overall athletic performance with personal information and the past evaluation result, stores the monitoring report in a database and sends the monitoring report to the intelligent interaction equipment by means of the network connection equipment;
step 316: the user obtains a report page for viewing and downloading;
as shown in fig. 5, a flowchart of a symptom detection method of a portable parkinsonism bradykinesia monitoring intervention device of the present invention, wherein the parkinsonism bradykinesia detection method comprises the steps of:
step 401: selecting a proper window function, and selecting the window length and the step length;
step 402: dividing a window and carrying out Fourier time-frequency domain transformation on acceleration data in the window;
step 403: calculating the total energy of the window according to the power spectrum after Fourier transformation;
step 404: acquiring inertial sensor data time/frequency domain characteristic data, including mean value, standard deviation, skewness, approximate entropy, amplitude and maximum starting speed;
step 405: acquiring patient interactive exercise task performance data, and calculating track tracking stationarity, character copying scale reduction change, pen-up hesitation, task time consumption and accuracy;
step 406: selecting a proper energy threshold and a bradykinesia threshold;
step 407: comparing the total energy in the window to an energy threshold;
step 408: judging whether the patient is in a static waiting state, if so, continuing monitoring, and if not, jumping to the step 409;
step 409: and according to the acquired inertial node data characteristics and the acquired interactive exercise task performance characteristics, carrying out statistical analysis, and comparing with a bradykinesia threshold value to judge whether the exercise is in a bradykinesia state or not.
Claims (1)
1. A portable parkinsonism bradykinesia monitoring intervention device which is characterized in that: the intelligent interaction device comprises wearable intelligent equipment, intelligent interaction equipment, sports intervention equipment, network connection equipment and information recording equipment;
the wearable intelligent device consists of a wearable inertial node worn in the middle section of an index finger and an intelligent bracelet worn on the wrist; the wearable inertia node is used for collecting finger movement data of a user and transmitting the finger movement data to the intelligent bracelet; the intelligent bracelet is used for acquiring wrist movement data, synchronizing and integrating finger movement information data, and transmitting the data to the intelligent interaction equipment; the wearable inertial node and the intelligent bracelet are provided with inertial sensors which are used for collecting acceleration data, angular velocity data and magnetic field intensity data;
the intelligent interaction equipment provides data management, result evaluation and intervention instruction issuing; the intelligent interaction device is an electronic device which is provided with a high-definition display screen and has network communication capability, and comprises a touch screen notebook computer, a tablet computer or a smart phone, and can acquire and process data when a patient executes an interaction task; the intelligent interaction equipment is used for collecting interaction motion data of a user in an interaction task, extracting characteristic values from all motion data collected by the intelligent interaction equipment and the wearable intelligent equipment, inputting the characteristic values into an evaluation model for evaluation analysis, and obtaining and displaying an evaluation result; all the acquired motion data comprise inertial sensor data and interaction motion data when fingers and wrists move; the extracted characteristic values comprise inertial sensor data time/frequency domain characteristics and interactive motion task performance characteristics, wherein the inertial sensor data time/frequency domain characteristics comprise mean values, standard deviations, skewness, approximate entropy, amplitude and maximum starting speed, and the interactive motion task performance characteristics comprise track tracking stationarity, character copying scale reduction change, pen-starting hesitation, task time consumption and accuracy; in the monitoring process, interactive software is operated on the intelligent interactive equipment, two monitoring scene selections of conventional monitoring and silent monitoring are provided for a user, the conventional monitoring corresponds to a task monitoring intervention mode, and the silent monitoring corresponds to a silent monitoring intervention mode; the task monitoring intervention mode is that a user is guided to complete an interaction task through intelligent interaction equipment, at the moment, the intelligent interaction equipment gives the interaction task, the task guidance is shown on a display screen, finger kneading, grasping actions, handwriting track copying and character copying tasks with strong continuity randomly occur, in the task execution process, the intelligent interaction equipment judges whether specific task execution quality is qualified or not, data are collected if the specific task execution quality is qualified, the data are abandoned if the specific task execution quality is unqualified, a motion retardation state is monitored according to motion information data during the process, and motion intervention is carried out through the motion intervention equipment if the motion intervention state is achieved; the monitoring target of the silence monitoring intervention mode is the daily activities of the user, the wearable inertial node can be selectively removed, during the period, the intelligent bracelet monitors the motion retardation state according to the motion data of the daily life of the user, and if the motion intervention state is reached, the motion intervention is carried out through the motion intervention equipment; in the evaluation and analysis process, the intelligent interaction equipment utilizes the acceleration rate of the inertial sensor to count the total energy of the power spectrum in a specific window to judge whether a user is in a static waiting task state, so that misjudgment of a bradykinesia state is effectively avoided, meanwhile, the judgment is carried out on whether the state is an 'intervention' state according to the comparison of the evaluation result and a preset threshold value, and an intervention instruction is sent underground based on the selection; in addition, the intelligent interaction device is also used for sending the evaluation result to the information recording device through the network connection device;
the portable parkinsonism bradykinesia monitoring and intervention device has the advantages that more available features are excavated, the inertial sensor is used for capturing finger pinching and full-hand grasping motion features, the intelligent interaction device is used for capturing feature data in track tracking and character copying tasks, and the use of complementary features effectively improves detection accuracy;
the exercise intervention equipment performs action intervention correction on the 'corresponding intervention' state according to the evaluation result, namely the Bluetooth earphone gives out audio prompt signals with different intensities and durations under the condition of occurrence of different degrees of exercise retardation, and helps a user to execute an action intervention correction task so as to achieve the purpose of reducing upper limb exercise and cognitive reaction retardation through self exercise intervention;
the information recording equipment is arranged at the far end and is used for storing the staged monitoring evaluation result into the database;
the network connection device comprises a router device and can stably and reliably complete network communication between the intelligent interaction device and the information recording device;
the wearable inertial node includes: the system comprises a first inertial sensor, a first data storage module, a first Bluetooth communication module, a first microcontroller, a first power management module, a first battery and a first data interface; the intelligent bracelet comprises a second inertial sensor, a second data storage module, a second Bluetooth communication module, a second microcontroller, a second power management module, a second battery and a second data interface;
the first inertial sensor is independently worn and is used for collecting acceleration data, angular velocity data and magnetic field intensity data;
the first data storage module is used for storing data acquired by the first inertial sensor;
the first Bluetooth communication module is used for transmitting the data detected by the first inertial sensor to the intelligent bracelet;
the first microcontroller is used for controlling the first inertial sensor to collect data and controlling the first Bluetooth communication module to interact data and instructions with the intelligent bracelet;
the first power management module is used for carrying out power management on the first inertial sensor and guaranteeing normal power supply and stable battery endurance time;
the first battery supplies power to the first inertial sensor;
the first data interface is used for charging and data wired downloading;
the second inertial sensor is embedded and can be embedded into the intelligent bracelet and used for collecting acceleration data, angular velocity data and magnetic field intensity data;
the second data storage module is used for storing data acquired by the second inertial sensor;
the second Bluetooth communication module is used for carrying out Bluetooth communication with the wearable inertial node to obtain data and sending the regular motion information data to the intelligent interaction device;
the second microcontroller is used for controlling the second inertial sensor to acquire data and controlling the second inertial sensor to perform data synchronization and integration with the wearable inertial node; in addition, the second Bluetooth communication module is used for controlling the second Bluetooth communication module to interact data and instructions with the intelligent bracelet and the intelligent interaction equipment;
the second power management module is used for carrying out power management on the intelligent bracelet, so that normal power supply and stable battery endurance time are ensured;
the second battery supplies power for the intelligent bracelet;
the second data interface is used for charging and data wired downloading;
the first data interface and the second data interface have the same structure and are used for assembling and disassembling the waterproof rubber cover seal;
the motion intervention device is a Bluetooth earphone, is connected with the intelligent interaction device in a Bluetooth mode, and receives a feedback signal of the intelligent interaction device to execute an action correction intervention task;
the wearable inertia node is fixed by a plastic element, and the plastic element is a ring-shaped element made of elastic memory material and is used for fixing the wearable inertia node to an index finger;
the wearable inertial node is miniature, has small mass and has an attaching area not more than 0.8cm 2 The mass is not more than 3g, so that the intervention on the movement of a user can be reduced as much as possible;
the intelligent bracelet is multifunctional, and comprises the steps of acquiring wrist motion data of a user by means of an embedded inertial sensor of the intelligent bracelet, synchronizing the wrist motion data with finger motion data acquired by a wearable inertial node at an index finger, and performing data and instruction interaction with the intelligent interaction equipment;
running interactive software on the intelligent interactive equipment; the interactive software guides the user to log in by a personal mode, and further provides monitoring mode selection, interactive task execution and evaluation result display functions for the user; the monitoring mode selection is provided for different monitoring scene selections of a user, such as unconstrained regular monitoring or silence monitoring when the monitoring is inconvenient temporarily, and the intelligent interaction device executes different monitoring activities corresponding to different monitoring modes; the intelligent interaction device guides a user to conduct interaction tasks of handwriting trace copying, repeated writing of characters with strong continuity, fine movement reaction and nerve sensitivity reaction such as a mouse playing game; the evaluation result display is that the motion monitoring performance of the user is displayed in the interactive software display frame in real time, and in addition, when the monitoring is finished, the interactive software displays a monitoring report sheet of the whole monitoring process;
the working mode of the portable parkinsonism bradykinesia monitoring intervention device comprises the following steps:
step 301: opening a wearable inertia node and an intelligent bracelet;
step 302: starting intelligent interaction equipment and starting interaction software, initializing operation, and starting and connecting a Bluetooth headset;
step 303: inputting basic information of a patient in interactive software, wherein the basic information comprises name, gender, age, weight and illness time information;
step 304: in the interactive software, clicking a connection inertia node, clicking a calibration button, clicking a connection Bluetooth headset, and clicking an initialization button;
step 305: inputting relevant configuration information of the information recording equipment in the interactive software, and clicking connection;
step 306: the wearable inertial node of the device on the plastic element is fixed at the front position of the middle end of the index finger of a user, the front end of the fixed position is provided with a finger part enough for executing interaction tasks, and the user wears an intelligent bracelet and a Bluetooth headset;
step 307: clicking a conventional monitoring button in interactive software;
step 308: the intelligent interaction equipment gives out an interaction task, a display screen shows task guidance, finger kneading, gripping actions, handwriting track copying and strong-consistency character copying tasks randomly appear, and in the task execution process, the intelligent interaction equipment judges whether the specific task execution quality is qualified or not, data are collected if the specific task execution quality is qualified, and the data are discarded if the specific task execution quality is unqualified;
step 309: in the working process, the intelligent interaction equipment extracts relevant characteristic values of bradykinesia according to all the motion data acquired by the intelligent interaction equipment and the wearable intelligent equipment, and then carries out classification quantitative detection evaluation according to the characteristic values to obtain an evaluation result and displays the evaluation result;
step 310: when the monitoring score reaches an 'intervention-needed' state, the intelligent interaction device sends a corresponding exercise correction intervention instruction to the exercise intervention device according to the measurement score, and at the moment, the user receives an audio prompt intervention signal to perform self exercise intervention;
step 311: the intelligent interaction equipment generates a periodic monitoring evaluation report at intervals and sends the periodic monitoring evaluation report to the information recording equipment through the network connection equipment;
step 312: the information recording equipment receives the report and stores the report into a database in combination with personal information of the user;
step 313: the user selects and clicks the buttons of 'continue', 'silence monitor', 'end monitor' in the interactive software, if 'continue' is selected, the step goes to 308, if 'silence monitor' is selected, the wearable inertial node is selectively removed, the interactive task is stopped, the daily activity is changed to be monitored, the step goes to 310, if 'end monitor' is selected, the step goes to 314;
step 314: all inertial sensors stop data acquisition, and the Bluetooth earphone is closed;
step 315: the information recording equipment generates a monitoring report by combining the overall athletic performance with personal information and the past evaluation result, stores the monitoring report in a database and sends the monitoring report to the intelligent interaction equipment by means of the network connection equipment;
step 316: the user obtains a report page for viewing and downloading;
the bradykinesia detection method comprises the following steps:
step 401: selecting a proper window function, and selecting the window length and the step length;
step 402: dividing a window and carrying out Fourier time-frequency domain transformation on acceleration data in the window;
step 403: calculating the total energy of the window according to the power spectrum after Fourier transformation;
step 404: acquiring time/frequency domain characteristics of inertial sensor data, including mean value, standard deviation, skewness, approximate entropy, amplitude and maximum starting speed;
step 405: acquiring the performance characteristics of the interactive exercise task of the patient, including track tracking stationarity, character copying scale reduction change, pen-up hesitation, task time consumption and accuracy;
step 406: selecting a set energy threshold and a bradykinesia threshold;
step 407: comparing the total energy in the window to an energy threshold;
step 408: judging whether the patient is in a static waiting state, if so, continuing monitoring, and if not, jumping to the step 409;
step 409: and according to the acquired time/frequency domain characteristics of the inertial sensor data and the interactive exercise task performance characteristics, carrying out statistical analysis, and comparing with a bradykinesia threshold value to judge whether the inertial sensor data is in a bradykinesia state or not.
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