CN111012308B - Method, device and system for measuring dynamic multispectral absorption characteristic parameters of body surface - Google Patents

Method, device and system for measuring dynamic multispectral absorption characteristic parameters of body surface Download PDF

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CN111012308B
CN111012308B CN201911214325.9A CN201911214325A CN111012308B CN 111012308 B CN111012308 B CN 111012308B CN 201911214325 A CN201911214325 A CN 201911214325A CN 111012308 B CN111012308 B CN 111012308B
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body surface
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absorbance
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CN111012308A (en
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刘长松
陈彦
王小捷
王丽婷
赵强
甄黎明
王言伟
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Tsinghua University
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    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/00Measuring for diagnostic purposes; Identification of persons
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters

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Abstract

The embodiment of the invention provides a method, a device and a system for measuring dynamic multispectral absorption characteristic parameters of a body surface, wherein the method comprises the following steps: acquiring a first emergent light signal of a first position point and a second emergent light signal of a second position point after the first emergent light signal and the second emergent light signal are incident on the body surface of a detected body and transmitted by the detected body, and decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics; and acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by two position points, thereby obtaining a first characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface. According to the method, the device and the system for measuring the dynamic multispectral absorption characteristic parameters of the body surface, provided by the embodiment of the invention, the first emergent light signal and the second emergent light signal are decomposed into the preset multiple narrowband basic light signals, and the absorbance signal of each narrowband basic light signal corresponding to the position interval formed by the two position points is obtained, so that the acquisition of the dynamic multispectral absorption characteristic parameters of the body surface is realized.

Description

Method, device and system for measuring dynamic multispectral absorption characteristic parameters of body surface
Technical Field
The invention relates to the technical field of medicine and data processing, in particular to a method, a device and a system for measuring dynamic multispectral absorption characteristic parameters of a body surface.
Background
The body surface parts of animals such as human body and the like have rich arteriovenous vessels, and blood flow signals contain various information reflecting the physiological characteristics of the cardiovascular system of the animal body. Under the action of the heart's blood ejection, various physiological components on the body surface are dynamically changed. Along with the change of the cardiovascular system, the physiological components of the part to be detected also change, and how to represent the change of the physiological components of the animal body by using a parameter which is convenient for people to recognize and process has important theoretical and practical significance in the research of the physiological characteristics of the body surface of the human body.
The extraction of the dynamic multispectral absorption characteristic information of the body surface based on the optical signals needs to solve the following two problems.
The first problem is how to measure the signal attenuation degree of different wavelength light components in the composite optical signal at the part to be measured so as to obtain enough effective data as the signal representation of the static and dynamic physiological composition change of the human body.
The second problem is how to extract useful information from the measured values. In the measurement of optical signals, the position and length change of the crossing part affect the absorption of the optical signals, and further affect the effectiveness of the measured value, and the influence of the factors needs to be eliminated. The measured value contains various light component information and information of the light components changing along with time, and an effective method is needed for data analysis to obtain effective parameters reflecting the physiological characteristics of the human body.
Disclosure of Invention
To solve or at least partially solve the problems in the prior art, embodiments of the present invention provide a method, an apparatus, and a system for measuring dynamic multispectral absorption characteristic parameters of a body surface.
In a first aspect, an embodiment of the present invention provides a method for measuring a dynamic multispectral absorption characteristic parameter of a body surface, including: acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point; respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics; and acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
Further, the expression of the absorbance signal is:
A=log(Ia/Ib),
wherein A represents the absorbance signal, IaRepresenting the illumination intensity, I, of said narrowband optical signal at said first location pointbRepresenting the illumination intensity of the narrowband optical signal at the second location point.
Further, the method further comprises: acquiring an absorbance change waveform of the absorbance signal corresponding to each narrow-band basic optical signal; and acquiring a second characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface according to the absorbance change waveform.
Further, the acquiring a second characteristic parameter for characterizing a dynamic multispectral absorption characteristic of a body surface according to the absorbance change waveform includes: selecting one of the narrow-band basic optical signals as a reference optical signal, acquiring average brightness change waveforms of the reference optical signal corresponding to the first position point and the second position point, and acquiring a first time corresponding to a trough of the average brightness change waveform and a second time corresponding to a crest of the average brightness change waveform; respectively acquiring absorbance difference values of each narrow-band basic optical signal corresponding to the first time and the second time according to the absorbance change waveform; and acquiring the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal, thereby obtaining a second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface.
Further, the method further comprises: and acquiring the ratio of the narrow-band basic optical signals to the absorbance signals at the second time so as to obtain a third characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
In a second aspect, an embodiment of the present invention provides a device for measuring a dynamic multispectral absorption characteristic parameter of a body surface, including: an optical signal acquisition module to: acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point; a light pre-processing module to: respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics; a characteristic parameter obtaining module, configured to: and acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
In a third aspect, an embodiment of the present invention provides a system for measuring a body surface dynamic multispectral absorption characteristic parameter, including a measurement device and a signal acquisition device for the body surface dynamic multispectral absorption characteristic parameter; the signal acquisition device comprises an incident light source module, a photoelectric sensor module and an output module, wherein: the incident light source module is used for sending an incident light signal to the body surface; the two photoelectric sensor modules are respectively used for acquiring the first emergent light signal and the second emergent light signal; the output module is used for sending the first emergent light signal and the second emergent light signal to the measuring device of the dynamic multispectral absorption characteristic parameters of the body surface.
In a fourth aspect, an embodiment of the present invention provides an electronic device, which includes a memory, a processor, and a computer program stored in the memory and executable on the processor, and the processor implements the steps of the method provided in the first aspect when executing the computer program.
In a fifth aspect, an embodiment of the present invention provides a non-transitory computer readable storage medium, on which a computer program is stored, which when executed by a processor implements the steps of the method as provided in the first aspect.
According to the method, the device and the system for measuring the dynamic multispectral absorption characteristic parameters of the body surface, provided by the embodiment of the invention, the first emergent light signal and the second emergent light signal emitted from the first position point and the second position point of the measured body are decomposed into a plurality of preset narrow-band basic light signals according to the spectral characteristics, and the absorbance signal of each narrow-band basic light signal corresponding to the position interval formed by the first position point and the second position point is obtained, so that the acquisition of the dynamic multispectral absorption characteristic parameters of the body surface is realized, and the method, the device and the system can be used for representing the change of the physiological components of an animal body.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a flowchart of a method for measuring dynamic multispectral absorption characteristic parameters of a body surface according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a device for measuring dynamic multispectral absorption characteristics of a body surface according to an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of a system for measuring dynamic multispectral absorption characteristics of a body surface according to an embodiment of the present invention;
FIG. 4 is a schematic structural diagram of a signal acquisition device in a system for measuring dynamic multispectral absorption characteristic parameters of a body surface according to an embodiment of the present invention;
FIG. 5 is a flowchart of a method for measuring dynamic multispectral absorption characteristics of a body surface according to another embodiment of the present invention;
FIG. 6 is a schematic view illustrating decomposition of optical signals in a method for measuring dynamic multispectral absorption characteristics of a body surface according to an embodiment of the present invention;
FIG. 7 is a schematic diagram illustrating the variation of components of the body surface at different times according to the method for measuring the dynamic multi-spectral absorption characteristic parameters of the body surface of the embodiment of the present invention;
FIG. 8 is a schematic diagram of an absorbance change waveform in the method for measuring the dynamic multispectral absorption characteristic parameters of the body surface according to an embodiment of the present invention;
fig. 9 is a schematic physical structure diagram of an electronic device according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Fig. 1 is a flowchart of a method for measuring a dynamic multispectral absorption characteristic parameter of a body surface according to an embodiment of the present invention. As shown in fig. 1, the method includes:
step 101, acquiring a first emergent light signal which is incident on the body surface of a detected body and is emitted from a first position point after being transmitted by the detected body and a second emergent light signal which is emitted from a second position point.
The measuring device of the dynamic multispectral absorption characteristic parameters of the body surface obtains a first emergent light signal emitted to the body surface of a measured body and emitted from a first position point and a second emergent light signal emitted from a second position point after being transmitted by the measured body.
The first position point and the second position point are preset positions on the measured body related to measurement. The light source irradiates light on the body surface of the measured body, and the light source does not directly irradiate on the first position point or the second position point but irradiates other positions of the measured body. After the incident light irradiates on the body surface of the measured body, the light is transmitted (for example, can be transmitted through the body surface skin) by the measured body and then is emitted from the first position point and the second position point of the measured body. The first emergent light signal is a light signal emitted from the first position point, and the second emergent light signal is a light signal emitted from the second position point. The first emergent light signal and the second emergent light signal can be received by the photoelectric sensor and subjected to photoelectric conversion, so that subsequent analysis and processing are facilitated.
The measuring device of the dynamic multispectral absorption characteristic parameters of the body surface can acquire a first emergent light signal and a second emergent light signal from the photoelectric sensor.
And 102, decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics.
And the measuring device for the dynamic multispectral absorption characteristic parameters of the body surface decomposes the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics. For example, the first outgoing light signal and the second outgoing light signal may be decomposed into a red light signal, a green light signal, and a blue light signal, respectively.
Step 103, acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing a dynamic multispectral absorption characteristic of the body surface.
The absorbance signal reflects the amount of light absorption of the incident light when transmitted in the position interval constituted by the first position point and the second position point, and can be calculated by the following formula:
A=log(Ia/Ib),
wherein A represents the absorbance signal, IaRepresenting the illumination intensity, I, of said narrowband optical signal at said first location pointbRepresenting the illumination intensity of the narrowband optical signal at the second location point.
For example, for a red light signal, the corresponding absorbance signal is denoted as AR=log(IR a/IR b) Subscript R represents red light; for the green signal, the corresponding absorbance signal is denoted AG=log(IG a/IG b) Subscript G represents green light; for the blue signal, the corresponding absorbance signal is denoted as AB=log(IB a/IB b) Subscript B represents blue light; superscripts a, b denote a first position and a second position, respectively.
The absorbance signal of each narrow-band basic optical signal corresponding to the position interval formed by the first position point and the second position point can represent the dynamic multispectral absorption characteristics of the body surface, for example, the absorbance signal corresponding to each moment can be used as a parameter reflecting the body surface components at the moment. Therefore, the acquisition of the first characteristic parameter for characterizing the dynamic multispectral absorption characteristics of the body surface, namely the absorbance signal of each narrow-band basic optical signal corresponding to the position interval formed by the first position point and the second position point is realized.
According to the embodiment of the invention, the first emergent light signal and the second emergent light signal emitted from the first position point and the second position point of the tested body are decomposed into a plurality of preset narrow-band basic light signals according to the spectral characteristics, and the absorbance signal of each narrow-band basic light signal corresponding to the position interval formed by the first position point and the second position point is obtained, so that the acquisition of the dynamic multi-spectral absorption characteristic parameters of the body surface is realized, and the dynamic multi-spectral absorption characteristic parameters can be used for representing the change of the physiological components of the animal body.
Further, based on the above embodiment, the method further includes: acquiring an absorbance change waveform of the absorbance signal corresponding to each narrow-band basic optical signal; and acquiring a second characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface according to the absorbance change waveform.
And acquiring the absorbance change waveform of the absorbance signal corresponding to each narrow-band basic optical signal. According to the fluctuation change characteristics of the waveform, second characteristic parameters for representing the dynamic multispectral absorption characteristics of the body surface can be obtained so as to reflect the change condition of the physiological components.
On the basis of the above embodiment, the embodiment of the invention obtains the second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface according to the absorbance change waveform by obtaining the absorbance change waveform of the absorbance signal corresponding to each narrowband basic optical signal, so that the method can obtain the dynamic multispectral absorption characteristic parameter of the body surface according to the absorbance change waveform, and can be used for representing the change of the physiological components of the animal body.
Further, based on the above embodiment, the acquiring, according to the absorbance change waveform, a second characteristic parameter for characterizing a dynamic multispectral absorption characteristic of a body surface includes: selecting one of the narrow-band basic optical signals as a reference optical signal, acquiring average brightness change waveforms of the reference optical signal corresponding to the first position point and the second position point, and acquiring a first time corresponding to a trough of the average brightness change waveform and a second time corresponding to a crest of the average brightness change waveform; respectively acquiring absorbance difference values of each narrow-band basic optical signal corresponding to the first time and the second time according to the absorbance change waveform; and acquiring the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal, thereby obtaining a second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface.
And when second characteristic parameters for representing the dynamic multispectral absorption characteristics of the body surface are acquired according to the absorbance change waveform, selecting one of the narrow-band basic optical signals as a reference optical signal, and if the sensitivity of various narrow-band basic optical signals to physiological component changes is known, selecting the narrow-band basic optical signal which is more sensitive or most sensitive to the physiological component changes as the reference optical signal. And acquiring average brightness variation waveforms of the reference light signal corresponding to the first position point and the second position point, wherein the average brightness variation waveforms are waveforms corresponding to the average brightness values of the first position point and the second position point. And acquiring a first time corresponding to a trough and a second time corresponding to a peak of the average brightness variation waveform. The first time corresponds to the moment with the most dynamic change components of the body surface, and the second time corresponds to the moment with the least dynamic change components of the body surface. The dynamically changing component at the second moment can be considered to be zero, and only the statically unchanged component exists.
And respectively acquiring absorbance difference values of the narrow-band basic optical signals corresponding to the first time and the second time according to the absorbance change waveform. The absorbance difference value may be a difference between a value of the absorbance signal at the first time and a value of the absorbance signal at the second time. And acquiring the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal, wherein the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal is irrelevant to the distance between the two position points and the density of the dynamic change component, and is only relevant to the physical property of the absorbance of the dynamic change component of the position interval formed by the two position points under the narrow-band basic optical signal. Thereby obtaining a second characteristic parameter for characterizing the dynamic multispectral absorption characteristics of the body surface. The second characteristic parameter can be used as the characteristic parameter reflecting the dynamic change component of the body surface.
On the basis of the above embodiment, in the embodiment of the present invention, the ratio of the absorbance difference values corresponding to each narrowband basic optical signal is obtained, so as to obtain the second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface, and obtain the characteristic parameter reflecting the dynamic change component of the body surface.
Further, based on the above embodiment, the method further includes: and acquiring the ratio of the narrow-band basic optical signals to the absorbance signals at the second time so as to obtain a third characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
As previously described, the first time corresponds to a time when the dynamic change components of the body surface are the most, and the second time corresponds to a time when the dynamic change components of the body surface are the least. The dynamically changing component at the second moment can be considered to be zero, and only the statically unchanged component exists. And acquiring the ratio of the narrow-band basic optical signals to the absorbance signals corresponding to the second time, wherein the ratio can be used as a characteristic parameter for representing a static constant component of the surface in a cardiac cycle, so as to obtain a third characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface.
On the basis of the above embodiment, in the embodiment of the present invention, the ratio of the absorbance signal corresponding to the second time to each narrowband basic optical signal is obtained, so as to obtain the third characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface, and obtain the characteristic parameter reflecting the static invariant component of the body surface.
For measuring the physiological characteristics of the human body, the characteristic parameters acquired by the embodiment of the invention can represent the local body surface composition change generated by the arterial congestion in the skin in one cardiac cycle, and can be used for further research on the physiological characteristics of the human body.
Fig. 2 is a schematic structural diagram of a device for measuring a dynamic multispectral absorption characteristic parameter of a body surface according to an embodiment of the present invention. As shown in fig. 2, the apparatus includes an optical signal obtaining module 10, an optical preprocessing module 20, and a characteristic parameter obtaining module 30, wherein: the optical signal acquisition module 10 is configured to: acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point; the optical pre-processing module 20 is configured to: respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics; the characteristic parameter obtaining module 30 is configured to: and acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
According to the embodiment of the invention, the first emergent light signal and the second emergent light signal emitted from the first position point and the second position point of the tested body are decomposed into a plurality of preset narrow-band basic light signals according to the spectral characteristics, and the absorbance signal of each narrow-band basic light signal corresponding to the position interval formed by the first position point and the second position point is obtained, so that the acquisition of the dynamic multi-spectral absorption characteristic parameters of the body surface is realized, and the dynamic multi-spectral absorption characteristic parameters can be used for representing the change of the physiological components of the animal body.
Further, based on the above embodiment, the feature parameter obtaining module 30 is further configured to: acquiring an absorbance change waveform of the absorbance signal corresponding to each narrow-band basic optical signal; and acquiring a second characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface according to the absorbance change waveform.
On the basis of the above embodiment, the embodiment of the invention obtains the second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface according to the absorbance change waveform by obtaining the absorbance change waveform of the absorbance signal corresponding to each narrowband basic optical signal, so that the method can obtain the dynamic multispectral absorption characteristic parameter of the body surface according to the absorbance change waveform, and can be used for representing the change of the physiological components of the animal body.
Further, based on the above embodiment, when the characteristic parameter obtaining module 30 is configured to obtain the second characteristic parameter for characterizing the dynamic multispectral absorption characteristic of the body surface according to the absorbance variation waveform, specifically: selecting one of the narrow-band basic optical signals as a reference optical signal, acquiring a brightness change waveform of the reference optical signal, and acquiring a first time corresponding to a trough and a second time corresponding to a crest of the brightness change waveform; respectively acquiring absorbance difference values of each narrow-band basic optical signal corresponding to the first time and the second time according to the absorbance change waveform; and acquiring the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal, thereby obtaining a second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface.
On the basis of the above embodiment, in the embodiment of the present invention, the ratio of the absorbance difference values corresponding to each narrowband basic optical signal is obtained, so as to obtain the second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface, and obtain the characteristic parameter reflecting the dynamic change component of the body surface.
Further, based on the above embodiment, the feature parameter obtaining module 30 is further configured to: and acquiring the ratio of the narrow-band basic optical signals to the absorbance signals at the second time so as to obtain a third characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
On the basis of the above embodiment, in the embodiment of the present invention, the ratio of the absorbance signal corresponding to the second time to each narrowband basic optical signal is obtained, so as to obtain the third characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface, and obtain the characteristic parameter reflecting the static invariant component of the body surface.
Fig. 3 is a schematic structural diagram of a system for measuring dynamic multispectral absorption characteristic parameters of a body surface according to an embodiment of the present invention. As shown in fig. 3, the system includes a measuring device 1 and a signal collecting device 2 for measuring dynamic multispectral absorption characteristic parameters of a body surface, where the signal collecting device 2 includes an incident light source module, a photoelectric sensor module, and an output module, where: the incident light source module is used for sending an incident light signal to the body surface; the two photoelectric sensor modules are respectively used for acquiring the first emergent light signal and the second emergent light signal; the output module is used for sending the first emergent light signal and the second emergent light signal to the measuring device of the dynamic multispectral absorption characteristic parameters of the body surface.
The incident light source module is used for emitting incident light signals to a body surface, after the incident light signals are transmitted through the body surface, first emergent light signals emitted from a first position point are received by the first photoelectric sensor module, second emergent light signals emitted from a second position point are received by the second photoelectric sensor module, and the first emergent light signals and the second emergent light signals are converted into electric signals respectively. The output module receives the first emergent light signal and the second emergent light signal which are converted into electric signals, and directly sends the electric signals to the measuring device of the dynamic multispectral absorption characteristic parameters of the body surface or sends the electric signals to the measuring device of the dynamic multispectral absorption characteristic parameters of the body surface after analog-to-digital conversion. And the measuring device of the dynamic multispectral absorption characteristic parameters of the body surface measures the dynamic multispectral absorption characteristic parameters of the body surface after receiving the first emergent light signal and the second emergent light signal.
On the basis of the embodiment, the embodiment of the invention ensures the reliable acquisition of the measured optical signals of the dynamic multispectral absorption characteristic parameters of the body surface by reasonably arranging the signal acquisition device and forming the measurement system of the dynamic multispectral absorption characteristic parameters of the body surface with the measurement device of the dynamic multispectral absorption characteristic parameters of the body surface.
Further, based on the above embodiment, the incident light signal is a broadband mixed light signal, and the photosensor module includes a plurality of photosensors for receiving a predetermined narrowband light signal; or, the incident light signal is a plurality of narrow-band light signals which are emitted alternately, and the photoelectric sensor module comprises a single photoelectric sensor.
The incident light signal emitted by the incident light source module may be a broadband mixed light signal or a narrowband light signal emitted alternately. When the incident light signal is a broadband mixed light signal, in order to acquire each narrowband light signal, the photosensor module includes a plurality of photosensors for receiving preset narrowband light signals, and each photosensor is configured to receive a corresponding preset narrowband light signal. When the incident light signal is a plurality of alternately emitted narrow-band light signals, the photoelectric sensor module can only contain a single photoelectric sensor, alternately receive each narrow-band light signal, and also can realize the acquisition of different narrow-band light signals.
On the basis of the above embodiments, in the embodiments of the present invention, when the incident light signal is a broadband mixed light signal, the photosensor module includes a plurality of photosensors for receiving a predetermined narrowband light signal; when the incident light signal is a plurality of narrow-band light signals which are alternately sent out, the photoelectric sensor module comprises a single photoelectric sensor, and the flexibility of the structure of the signal acquisition device is improved.
Fig. 4 is a schematic structural diagram of a signal acquisition device in a system for measuring a dynamic multispectral absorption characteristic parameter of a body surface according to an embodiment of the present invention. FIG. 5 is a flowchart of a method for measuring dynamic multispectral absorption characteristics of a body surface according to another embodiment of the present invention. FIG. 6 is a schematic view of optical signal decomposition in the method for measuring the dynamic multispectral absorption characteristic parameters of the body surface according to an embodiment of the present invention. FIG. 7 is a schematic diagram illustrating the variation of components of the body surface at different times according to the method for measuring the dynamic multi-spectral absorption characteristic parameters of the body surface of the embodiment of the present invention. FIG. 8 is a schematic diagram of an absorbance change waveform in the method for measuring the dynamic multispectral absorption characteristic parameters of the body surface according to an embodiment of the present invention. The following describes in detail the method, apparatus and system for measuring the dynamic multispectral absorption characteristic parameters of the body surface according to the embodiments of the present invention with reference to fig. 4 to 8.
As shown in fig. 4, the signal acquisition device provided by the embodiment of the present invention is composed of the following module components: the emission light source module 210 may emit a broadband mixed light signal or a plurality of narrow-band light signals to the body surface; the photoelectric sensor module 220 can receive optical signals which are emitted by an incident light source and transmitted by a certain distance in the skin of the body surface at least two position points a and b on the body surface respectively, and form analog electric signals of two different position points through photoelectric conversion; the output module 230 outputs the analog electrical signal directly or converts the analog electrical signal into a digital signal through AD conversion.
The emitting light source module 210 and the photo sensor module 220 can adopt the following two operation modes:
working mode 1: the method comprises the following steps that a transmitting light source sends out broadband mixed optical signals, a photoelectric sensor module of each position point comprises a plurality of narrow-band optical signal sensors, and several kinds of narrow-band optical signals are obtained at the same time;
the working mode 2 is as follows: the emitting light source alternately emits several narrow-band light signals, and the photoelectric sensor module of each position point comprises a single photoelectric sensor to alternately acquire several narrow-band light signals.
As shown in fig. 5, the method for measuring the dynamic multispectral absorption characteristic parameter of the body surface according to the embodiment of the present invention includes the following steps:
s1: the signal acquisition equipment based on the two-point photoelectric sensor acquires two-point optical signals.
The signal acquisition device based on the optical signal designed by the embodiment of the invention is utilized to acquire the optical signals of two position points on the part to be measured at a certain moment. As shown in fig. 4, when the light is collected, the light enters the object to be analyzed from the light source, when the light passes through two points a and b in the object to be analyzed, different physiological components between the two points absorb part of the light signals respectively, and part of the light enters the two photoelectric sensor modules from the two positions a and b, so as to obtain the photoelectric signals reflecting the illumination intensities of the two positions. The two photoelectric signals contain absorption information of different spectrums of the object to be analyzed, and the composition and distribution information of the object to be analyzed can be acquired by some analysis means.
S2: the light signal is decomposed into one or more basic light signals, and the absorbance between the two points is calculated. And acquiring the absorbance of the two point intervals to different basic optical signals based on the photoelectric signals acquired at the two positions. The basic optical signal refers to the narrowband basic optical signal.
Step S2 specifically includes the following steps:
s21: as shown in fig. 6, the acquired optical signal is decomposed into a plurality of basic optical signals according to spectral characteristics, and in this embodiment, the optical signal is decomposed into three basic optical signals according to three colors, namely red, green and blue;
s22: for a basic light signal, e.g. a red light signal, the intensity of light at two positions a and b is IR aAnd IR bAssuming that the illumination direction is from a to b, the absorbance A of the basic optical signal in the ab two-point interval is calculatedR
Figure BDA0002299067510000131
KRIs the red absorption coefficient, which is a constant related to the material of the absorber and to the red signal. L is the distance between two points, C is the concentration of the component to be analyzed between ab points.
S23: similarly to S22, the absorbances A of the two-point ab interval for other basic optical signals were calculatedGAnd AB
Figure BDA0002299067510000132
Figure BDA0002299067510000133
KGIs the green absorption coefficient, which is a constant related to the material of the absorber and the green signal. KBIs the blue light absorption coefficient, which is a constant related to the material of the light absorber and the blue light signal.
S3: and analyzing to obtain the time when the dynamic change components are the most and the least. And continuously collecting according to time, acquiring brightness change waveforms and absorbance change waveforms of two position points within a period of time, and acquiring the time when the dynamic components are at most and at least. As shown in fig. 8, the absorbance change waveforms of red, green, and blue light are shown from top to bottom, where the horizontal axis represents time and the vertical axis represents the value of the absorbance signal.
Step S3 specifically includes the following steps:
s31: continuously collecting according to time to obtain the time-varying waveforms of brightness and absorbance under various basic optical signals of two point intervals in a period of time;
s32: a basic light signal is selected, and the average brightness of two position points is calculated to obtain an average brightness change waveform. The waveform represents the average intensity change over a period of time of such a base light signal as it passes through the object to be analyzed;
s33: and performing peak and trough analysis by using the average brightness change waveform, and taking the peak and trough occurrence time as the minimum and maximum time of dynamic components of the part to be analyzed.
S4: and acquiring the absorbance conditions of the most and least dynamic change components at the moment, wherein the absorbance changes under different basic optical signals are used for representing the physiological characteristics of the constant components and the variable components of the object to be analyzed.
Further, the method for analyzing the static unchanged components and the dynamic changed components of the part to be analyzed by using the absorbance information, which is obtained in the step S33, and corresponds to the maximum dynamic components and the minimum time comprises the following steps;
s41: as shown in fig. 7, assuming that the maximum time of the dynamic component is T0, the minimum time is T1, the dynamic component is increased by Δ at the time T0 relative to the time T1, and for the interval of two position points, namely, the point a and the point b, on the object to be measured, the corresponding absorbance values at the time T0 are respectively
Figure BDA0002299067510000141
The absorbance values at the time T1 are respectively
Figure BDA0002299067510000142
Calculating the corresponding absorbance variable quantities to
Figure BDA0002299067510000143
Taking the red light signal as an example, the corresponding absorbance change can be calculated as follows:
Figure BDA0002299067510000144
thus, there are:
Figure BDA0002299067510000145
similarly, can calculate and obtain:
Figure BDA0002299067510000146
Figure BDA0002299067510000147
s42: and acquiring a proportional relation among absorbance variable quantities of several basic optical signals according to the absorbance variable quantities at two moments:
Figure BDA0002299067510000148
it can be seen that the proportional relationship is the distance L from the two points and the concentration C of the dynamically changing componentΔIndependent of the physical property K of the absorption coefficient of the dynamically changing component Delta in the two-position interval under a specific basic light signalR Δ,KG Δ,KB ΔAnd (4) correlating.
S43: using the proportional relation delta A of the absorbance change under several basic optical signalsR:ΔAG:ΔABAs a characteristic parameter for representing the dynamic variation components of the body surface generated by the blood arterial congestion in a cardiac cycle, the absorbance proportional relation A under several basic optical signals at the moment with the minimum dynamic variation componentsR:AG:ABAs a characteristic parameter characterizing the statically invariant component of the surface within a cardiac cycle. These parameters can be used for further studies on the physiological properties of the human body by means of various numerical analysis methods.
According to the method, the device and the system for measuring the dynamic multispectral absorption characteristics of the body surface, provided by the embodiment of the invention, the emergent light signals of two position points are acquired based on the photoelectric sensor, the absorbance between the two points is approximately calculated, and the waveform of the emergent light signals of the two points in a period of time changing along with time and the waveform of the absorbance changing are acquired and acquired for analyzing the physiological change characteristics between the two points. The variation waveform of the emergent light signal represents the variation of various basic light signal absorption characteristics caused by the variation of physiological components within a period of time, and parameters such as the time when the dynamic components occur at most and at least, the heart rate and the like can be obtained from the variation waveform, so that the calculation of the aspects such as the heart rate variation and the like can be carried out. The change relationship of the absorbance at the dynamic components at most and at least two time points can reflect the physiological change rule of the static unchanged components and the dynamic changed components of the part to be analyzed, and more human physiological parameter data can be obtained through further data analysis and processing.
The embodiment of the invention realizes the measurement of dynamic multispectral absorption characteristics of the body surface by collecting and processing optical signals of two position points of the body surface, and achieves the aim of carrying out noninvasive detection and analysis on the part to be analyzed. By using the two-point optical signal acquisition device provided by the embodiment of the invention, emergent light signals of two position points are acquired and converted into absorbance information between two points. The light signals are decomposed into multiple basic light signals, and the absorbance difference value of each basic light signal at two specific moments are obtained and are used for effectively representing the change rule of static unchanged components and dynamic changed components of the body surface. The methods are an innovative and more effective analysis approach for analyzing the physiological characteristics of the human body.
The device and the system provided by the embodiment of the invention are used for the method, and specific functions can refer to the method flow and are not described again.
Fig. 9 is a schematic physical structure diagram of an electronic device according to an embodiment of the present invention. As shown in fig. 9, the electronic device may include: a processor (processor)910, a communication Interface (Communications Interface)920, a memory (memory)930, and a communication bus 940, wherein the processor 910, the communication Interface 920, and the memory 930 communicate with each other via the communication bus 940. Processor 910 may invoke logic instructions in memory 930 to perform the following method: acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point; respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics; and acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
Furthermore, the logic instructions in the memory 930 may be implemented in software functional units and stored in a computer readable storage medium when the logic instructions are sold or used as independent products. Based on such understanding, the technical solution of the present invention may be embodied in the form of a software product, which is stored in a storage medium and includes instructions for causing a computer device (which may be a personal computer, a server, or a network device) to execute all or part of the steps of the method according to the embodiments of the present invention. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk or an optical disk, and other various media capable of storing program codes.
In another aspect, an embodiment of the present invention further provides a non-transitory computer-readable storage medium, on which a computer program is stored, where the computer program is implemented by a processor to perform the method provided by the foregoing embodiments, for example, including: acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point; respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics; and acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
The above-described embodiments of the apparatus are merely illustrative, and the units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution of the present embodiment. One of ordinary skill in the art can understand and implement it without inventive effort.
Through the above description of the embodiments, those skilled in the art will clearly understand that each embodiment can be implemented by software plus a necessary general hardware platform, and certainly can also be implemented by hardware. With this understanding in mind, the above-described technical solutions may be embodied in the form of a software product, which can be stored in a computer-readable storage medium such as ROM/RAM, magnetic disk, optical disk, etc., and includes instructions for causing a computer device (which may be a personal computer, a server, or a network device, etc.) to execute the methods described in the embodiments or some parts of the embodiments.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (8)

1. A method for measuring dynamic multispectral absorption characteristic parameters of a body surface is characterized by comprising the following steps:
acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point;
respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics;
acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing dynamic multispectral absorption characteristics of a body surface;
the method further comprises the following steps:
acquiring an absorbance change waveform of the absorbance signal corresponding to each narrow-band basic optical signal;
acquiring a second characteristic parameter for representing dynamic multispectral absorption characteristics of the body surface according to the absorbance change waveform;
the acquiring of the second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface according to the absorbance change waveform comprises the following steps:
selecting one of the narrow-band basic optical signals as a reference optical signal, acquiring average brightness change waveforms of the reference optical signal corresponding to the first position point and the second position point, and acquiring a first time corresponding to a trough of the average brightness change waveform and a second time corresponding to a crest of the average brightness change waveform;
respectively acquiring absorbance difference values of each narrow-band basic optical signal corresponding to the first time and the second time according to the absorbance change waveform;
and acquiring the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal, thereby obtaining a second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface.
2. The method for measuring a body surface dynamic multispectral absorption characteristic parameter according to claim 1, wherein the expression of the absorbance signal is as follows:
A=log(Ia/Ib),
wherein A represents the absorbance signal, IaRepresenting the illumination intensity, I, of said narrowband optical signal at said first location pointbRepresenting the illumination intensity of the narrowband optical signal at the second location point.
3. The method for measuring the body surface dynamic multispectral absorption characteristic parameters according to claim 1, further comprising:
and acquiring the ratio of the narrow-band basic optical signals to the absorbance signals at the second time so as to obtain a third characteristic parameter for representing the dynamic multispectral absorption characteristics of the body surface.
4. A measuring device for dynamic multispectral absorption characteristic parameters of a body surface is characterized by comprising:
an optical signal acquisition module to: acquiring a first emergent light signal which is incident on the body surface of a measured body and is emitted from a first position point after being transmitted by the measured body and a second emergent light signal which is emitted from a second position point;
a light pre-processing module to: respectively decomposing the first emergent light signal and the second emergent light signal into multiple preset narrow-band basic light signals according to spectral characteristics;
a characteristic parameter obtaining module, configured to: acquiring an absorbance signal of each narrow-band basic optical signal corresponding to a position interval formed by the first position point and the second position point, so as to obtain a first characteristic parameter for representing dynamic multispectral absorption characteristics of a body surface;
the characteristic parameter obtaining module is further configured to:
acquiring an absorbance change waveform of the absorbance signal corresponding to each narrow-band basic optical signal;
acquiring a second characteristic parameter for representing dynamic multispectral absorption characteristics of the body surface according to the absorbance change waveform;
the acquiring of the second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface according to the absorbance change waveform comprises the following steps:
selecting one of the narrow-band basic optical signals as a reference optical signal, acquiring average brightness change waveforms of the reference optical signal corresponding to the first position point and the second position point, and acquiring a first time corresponding to a trough of the average brightness change waveform and a second time corresponding to a crest of the average brightness change waveform;
respectively acquiring absorbance difference values of each narrow-band basic optical signal corresponding to the first time and the second time according to the absorbance change waveform;
and acquiring the ratio of the absorbance difference value corresponding to each narrow-band basic optical signal, thereby obtaining a second characteristic parameter for representing the dynamic multispectral absorption characteristic of the body surface.
5. A measurement system based on the measurement device for the body surface dynamic multispectral absorption characteristic parameters of claim 4, comprising: the measuring device and the signal acquisition device of the dynamic multispectral absorption characteristic parameters of the body surface; the signal acquisition device comprises an incident light source module, a photoelectric sensor module and an output module, wherein:
the incident light source module is used for sending an incident light signal to the body surface;
the two photoelectric sensor modules are respectively used for acquiring the first emergent light signal and the second emergent light signal;
the output module is used for sending the first emergent light signal and the second emergent light signal to the measuring device of the dynamic multispectral absorption characteristic parameters of the body surface.
6. The measurement system of claim 5, wherein the incident light signal is a broadband mixed light signal, and the photosensor module comprises a plurality of photosensors for receiving a predetermined narrow-band light signal; or, the incident light signal is a plurality of narrow-band light signals which are emitted alternately, and the photoelectric sensor module comprises a single photoelectric sensor.
7. An electronic device comprising a memory, a processor and a computer program stored on the memory and executable on the processor, wherein the processor executes the computer program to implement the steps of the method for measuring the body surface dynamic multi-spectral absorption characteristic parameter according to any one of claims 1 to 3.
8. A non-transitory computer-readable storage medium, on which a computer program is stored, wherein the computer program, when being executed by a processor, implements the steps of the method for measuring the dynamic multispectral absorption characteristic parameter of the body surface according to any one of claims 1 to 3.
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