CN110974897A - Spray for treating traumatic injury and mosquito bite and preparation method thereof - Google Patents

Spray for treating traumatic injury and mosquito bite and preparation method thereof Download PDF

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Publication number
CN110974897A
CN110974897A CN201911371052.9A CN201911371052A CN110974897A CN 110974897 A CN110974897 A CN 110974897A CN 201911371052 A CN201911371052 A CN 201911371052A CN 110974897 A CN110974897 A CN 110974897A
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spray
preparation
parts
traumatic injury
treating traumatic
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梁雪梅
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Shandong Liang's Chongdetang Medical Science And Technology Co ltd
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Shandong Liang's Chongdetang Medical Science And Technology Co ltd
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Priority to CN201911371052.9A priority Critical patent/CN110974897A/en
Publication of CN110974897A publication Critical patent/CN110974897A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/65Amphibians, e.g. toads, frogs, salamanders or newts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to the technical field of traditional Chinese medicine external spray, in particular to a spray for treating traumatic injury and mosquito bite and a preparation method thereof, wherein the spray comprises the following Chinese herbal medicines in parts by weight: mainly comprises principal drugs of saffron, dragon's blood, frankincense and myrrh which have the functions of removing blood stasis and reducing swelling and promoting blood circulation and removing obstruction in channels; ministerial drugs are compatible with venenum bufonis, raw radix aconiti and flos daturae for enhancing blood circulation and removing blood stasis and relieving swelling and pain; the medicine is prepared by soaking 10 Chinese medicinal materials including arisaema tuber, dahurian angelica root and cassia twig as assistant medicines in alcohol, removing dregs of a decoction, adding a blending agent, stirring, preparing a liquid medicine and filling the liquid medicine into a spray bottle.

Description

Spray for treating traumatic injury and mosquito bite and preparation method thereof
Technical Field
The invention relates to a spray for treating traumatic injury and mosquito bite and a preparation method thereof, belonging to the traditional Chinese medicine external spray.
Background
At present, the bone injury is generally treated in the medical field by adopting a stone fixation method, namely bone injury oral administration or applying a dampness and pain removing ointment, a musk tiger bone ointment, a dog skin ointment and the like, which have the required curative effect on treating the bone injury, but have undesirable parts, such as negative gypsum from the traditional Chinese medicine perspective, difficult blood circulation promotion and blood stasis removal of injured limbs, and heavy application, so that the injured limbs are inconvenient to move, unsmooth blood circulation and inconvenient for medical examination, and the malposition connection phenomenon of the injured limbs often occurs; oral medications also tend to be uncomfortable, such as: pseudo-ginseng and Shenyang red which are orally taken have poor anti-inflammatory and analgesic effects and even side effects, and some people can also suffer from nausea and vomiting after taking the ointment, for example, a dog skin ointment for treating sprain is very uncomfortable when being stuck on a body, and the curative and analgesic effects of a pain ointment for injury and dampness, a musk and tiger bone ointment and the like are not ideal.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide an external spray which is prepared from pure Chinese herbal medicines and is used for treating traumatic injury, and the external spray has good pain relieving effect, good blood circulation promoting and swelling reducing effect and high cure rate.
The invention is realized by mainly using saffron, dragon's blood, frankincense and myrrh which have the functions of removing blood stasis, reducing swelling, promoting blood circulation and removing obstruction in channels as main drugs; the ministerial drugs are compatible drugs of the toad venom and the raw radix aconiti for enhancing the blood circulation and the blood stasis and relieving the swelling and the pain; the wind-dispelling itch-relieving traditional Chinese medicine is prepared by soaking raw arisaema tuber, angelica dahurica and cassia twig which are used as adjuvant Chinese medicinal materials in alcohol, removing dregs of a decoction, adding a blending agent, stirring, preparing a spray and the like, and is characterized in that the effective components consist of the following raw materials in parts by weight.
Preferably, ① Main drugs for removing blood stasis, relieving swelling, promoting blood circulation and removing obstruction in channels, including saffron 40-45 parts, dragon's blood resin 10-20 parts, frankincense 15-30 parts, myrrh 10-20 parts.
Preferably, ② compatible medicines for promoting blood circulation, removing blood stasis, relieving swelling and pain, such as toad venom 0.1-0.2 parts, radix aconiti 15-30 parts and flos lonicerae 10-15 parts are used for the spray for treating traumatic injury, mosquito bite and the preparation method thereof.
Preferably, the ③ compatible medicine for detumescence, resolving hard mass, dispelling wind and arresting itching comprises 15 to 30 parts of arisaema consanguineum schott and 10 to 15 parts of dahurian angelica root.
Preferably, the spray for treating traumatic injury, mosquito bite and the preparation method thereof, ④ the collateral-flow-activating and channel-warming adjuvant comprises 10 to 15 parts of cassia twig.
Preferably, the plaster for traumatic injuries and the preparation method thereof, ⑤ seasonings comprise 500ml of glycerin, 200ml of wintergreen oil, 500ml of alcohol and 100g of camphor.
Preferably, the plaster for traumatic injury and sprain and the preparation method thereof comprise the following steps: the preparation method comprises the following steps of:
1. the high-quality pure medicinal materials which meet the national sanitary standard are purchased and weighed, and are processed and prepared under the environment which meets the national relevant sanitary standard for preparing the medicaments;
2. dissolving Camphora in ethanol.
3. Soaking 10 groups of medicinal materials in the components in 95% alcohol for 1 month;
4. leaching the group medicine soaked in alcohol with a strainer, taking out, removing the residue, and reserving the refined solution for later use;
5. and (3) adding glycerin and wintergreen oil into the prepared refined liquid successively while stirring, uniformly stirring, and filtering to obtain the liquid spray for later use.
5. According to the preparation method of normal size, 30 g of the prepared spray is taken and filled into a special packaging bottle designed in advance, and the finished spray for treating traumatic injury, sprain and mosquito bite is obtained.
The traumatic injury spraying agent prepared by the invention is an external spraying agent prepared from pure Chinese medicinal materials, can be directly externally applied to an injured part, has the effects of promoting blood circulation to remove blood stasis, relieving swelling and pain, dispelling wind and arresting itching, can play the roles of diminishing inflammation and relieving swelling, dispelling wind and removing dampness to relieve itching, and relaxing tendons and activating collaterals, has a good pain relieving effect and a high cure rate, is common in medicinal materials, low in price and easy to operate, can be accepted by common people, is short in treatment period, less in pain and low in cost, and avoids weak western medicine effect and large side effect on a body. The Chinese medicine has scientific and reasonable formula.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A spray for treating traumatic injury and mosquito bite and a preparation method thereof are disclosed, which are composed of the following Chinese herbal medicines in parts by weight: 40 to 45 portions of saffron, 10 to 20 portions of dragon's blood, 15 to 30 portions of frankincense and 10 to 20 portions of myrrh.
The embodiment 1 relates to a spray for treating traumatic injury and mosquito bite and a preparation method thereof, which comprises the following steps: the camphor is completely immersed and dissolved in the ethanol, all the group medicines in the components are immersed and soaked in 95% alcohol for 1 month, the group medicines soaked in the alcohol are leached and fished out, medicine dregs are removed, refined liquid is left to be half for standby, glycerin and wintergreen oil are added into the standby refined liquid while being added and stirred, and the liquid spray is obtained after filtration, and the liquid spray is used for standby after 30 g of the standby spray is taken according to the normal preparation method and filled into a special packaging bottle designed in advance, so that the finished spray for treating traumatic injury and mosquito bite is obtained.
Example 2
A spray for treating traumatic injury and mosquito bite and a preparation method thereof are provided, which are prepared by adding compatible medicines for promoting blood circulation to remove blood stasis and relieving swelling and pain on the basis of the Chinese herbal medicines in the embodiment 1 by weight: toad venom 0.1-0.2 weight portions of Sichuan aconite root 15-30 weight portions of cassia twig 10-15 weight portions.
Example 3
A plaster for traumatic injury and sprain and a preparation method thereof are provided, wherein the plaster is prepared by adding an adjuvant for reducing swelling, resolving masses, dispelling wind and arresting itching on the basis of the Chinese herbal medicines in the embodiments 1 and 2 by weight: 15-30 parts of raw arisaema tuber and 10-15 parts of dahurian angelica root.
Example 4
A plaster for traumatic injury and sprain and a preparation method thereof are provided, wherein the plaster for traumatic injury and sprain and the preparation method thereof are added with channel warming and collateral dredging adjuvants on the basis of the Chinese herbal medicines of the embodiments 1 and 3 by weight: 10-15 parts of cassia twig.
And (3) judging the curative effect:
1.1 general data the present invention was used to clinically observe and treat 45 men and 55 women in 100 cases of patients with shoulder joint sprain, acute waist sprain or muscle injury.
1.2 methods of treatment: the time is 30min, three times a day.
Typical cases are: random spot check of typical diseases: 1. the pain is hidden and painful when the acquired qi is cold, the waist is sprained again 2 days before, and the acute waist sprain is diagnosed by examination. Later, the spray of example 1 has obviously relieved the symptoms of the waist pain, completely disappears the pain feeling, and the queen women are recovered after 1 month without relapse and uncomfortable symptoms appear in the period.
2. For a certain male, age 45, muscle injury, joint swelling and pain, and difficulty in movement caused by long-term farming after elbow sprain, the soft tissue injury of the elbow is diagnosed by examination, the postspray is used for 3 times a day in example 1, the symptoms completely disappear after 3 days of application, and the disease does not relapse after 3 months of return visit.
3. When a certain plum is in the age of 44 years, the right wrist of a woman is sprained for 14 days after the woman lifts a heavy object, the pain is hard to endure, the holding is weak, the fracture of the torn wrist is checked by X-rays, the pain and swelling of the back of the hand are continuously relieved after the splint is fixed, and the pain and swelling of the wrist are obviously relieved after the plum is used in example 1, and the plum can normally move after the plum is continuously used for 1 week.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.

Claims (6)

1. The spray for treating traumatic injury and mosquito bite and the preparation method thereof are characterized in that the effective components are composed of the following raw materials according to the weight portion: saffron 40-45 parts, dragon's blood resin 10-20 parts, frankincense 15-30 parts and myrrh 10-20 parts as main medicine for treating blood stasis and swelling, promoting blood circulation and dredging meridian.
2. The spray for treating traumatic injury and mosquito bite and the preparation method thereof according to claim 1, characterized in that the compatible drugs are: 0.1 to 0.2 part of toad venom, 15 to 30 parts of unprocessed radix aconiti, 10 to 15 parts of flos lonicerae, and can enhance the effects of promoting blood circulation to remove blood stasis, and relieving swelling and pain.
3. The spray for treating traumatic injury and mosquito bite and the preparation method thereof according to claims 1 and 2, characterized in that the adjuvant comprises: 15-30 parts of raw arisaema tuber and 10-15 parts of dahurian angelica root, and has the functions of reducing swelling, resolving masses, dispelling wind and arresting itching.
4. The spray for treating traumatic injury and mosquito bite and the preparation method thereof according to claims 1 and 3 are characterized in that the channel warming and activating adjuvant: 10-15 parts of cassia twig.
5. The Dieda Niunio spray and its preparation method as claimed in claims 1 and 4, characterized in that said Dieda Niunio spray further comprises flavoring: 500ml of glycerin, 500ml of alcohol, 500ml of camphor, 100g of wintergreen oil and 200ml of wintergreen oil.
6. A spray for traumatic injury according to claims 1 and 5 and its preparation method, characterized in that, its preparation comprises the following steps:
① weighing the above high-quality pure medicinal materials meeting the national sanitary standard, and processing under the condition of meeting the national sanitary standard;
② dissolving Camphora in ethanol;
③ soaking all the above Chinese medicinal materials in 95% ethanol for 1 month;
④ soaking above herbs in ethanol, filtering, removing residues, and collecting extractive solution;
⑤ adding glycerol and wintergreen oil into the extractive solution while stirring, and filtering to obtain liquid spray;
⑥ the spray for treating traumatic injury, sprain, and insect bite is prepared by filling 30 g of the prepared spray into a special packaging spray bottle designed in advance according to the preparation method of normal size.
CN201911371052.9A 2019-12-25 2019-12-25 Spray for treating traumatic injury and mosquito bite and preparation method thereof Pending CN110974897A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698829A (en) * 2005-06-15 2005-11-23 李景辉 Ointment for trauma and injury and its preparation method
CN102949648A (en) * 2011-08-26 2013-03-06 吴岩 Traditional Chinese medicine for treating traumatic injury
CN104667124A (en) * 2015-02-03 2015-06-03 张德东 Traditional Chinese medicine composition capable of treating traumatic injuries and promoting factures to heal quickly

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698829A (en) * 2005-06-15 2005-11-23 李景辉 Ointment for trauma and injury and its preparation method
CN102949648A (en) * 2011-08-26 2013-03-06 吴岩 Traditional Chinese medicine for treating traumatic injury
CN104667124A (en) * 2015-02-03 2015-06-03 张德东 Traditional Chinese medicine composition capable of treating traumatic injuries and promoting factures to heal quickly

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
宋爱莉: "《365天的健康叮咛》", 28 February 2017, 青岛出版社 *
朱坤福: "《穴位敷贴治疗》", 31 July 2017, 吉林科学技术出版社 *
陈长虹: "《家庭生活健康宝典》", 31 May 2007, 中医古籍出版社 *

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