CN110963708A - Small dose injection is with borosilicate glass injection bottle - Google Patents
Small dose injection is with borosilicate glass injection bottle Download PDFInfo
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- CN110963708A CN110963708A CN201911331374.0A CN201911331374A CN110963708A CN 110963708 A CN110963708 A CN 110963708A CN 201911331374 A CN201911331374 A CN 201911331374A CN 110963708 A CN110963708 A CN 110963708A
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- parts
- injection
- borosilicate glass
- glass
- small
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Classifications
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- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C1/00—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B5/00—Melting in furnaces; Furnaces so far as specially adapted for glass manufacture
- C03B5/02—Melting in furnaces; Furnaces so far as specially adapted for glass manufacture in electric furnaces, e.g. by dielectric heating
- C03B5/027—Melting in furnaces; Furnaces so far as specially adapted for glass manufacture in electric furnaces, e.g. by dielectric heating by passing an electric current between electrodes immersed in the glass bath, i.e. by direct resistance heating
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B7/00—Distributors for the molten glass; Means for taking-off charges of molten glass; Producing the gob, e.g. controlling the gob shape, weight or delivery tact
- C03B7/02—Forehearths, i.e. feeder channels
- C03B7/06—Means for thermal conditioning or controlling the temperature of the glass
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C1/00—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels
- C03C1/004—Refining agents
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Geochemistry & Mineralogy (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Glass Compositions (AREA)
Abstract
The invention relates to a medium borosilicate glass injection bottle for small-dose injection, belonging to the field of medicinal glass. The composite material consists of the following raw materials in parts by mass: 250 parts of quartz sand 200, 10-13 parts of alumina, 1.0-2.5 parts of barium carbonate, 30-35 parts of boric acid, 35-40 parts of borax, 15-18 parts of sodium carbonate, 5-7 parts of sodium nitrate and 1.5-2.2 parts of cerium oxide; SiO is reasonably matched in the material formula2、Al2O3、B2O3、Na2The proportion of O and other components ensures that the glass performance reaches the neutral requirement. The gas rate is relatively low, and the mode of cold top melting is adopted, so that the volatilization of raw materials is reduced, and the pollution to the atmosphere is reduced. Cerium oxide is used to replace white arsenic as a clarifier, thereby avoiding toxic components in glassThe residue in the glass improves the use safety.
Description
Technical Field
The invention relates to a medium borosilicate glass injection bottle for small-dose injection, belonging to the field of medicinal glass.
Background
At present, small-dose medicament is often used in the injection process, so that small-dose medicament injection bottles are inevitable, and the small-dose medicament injection bottles are more and more along with the development of western medicine, however, in the small-volume injection for biological preparations, the main substance content is a medium borosilicate glass bottle, the formula is not reasonable at present, so that a borosilicate glass tube is used for hot processing, the surface of the borosilicate glass tube is damaged by a hot processing process, partial glass components are volatilized, and the amount of substances contained in the medicine is increased.
The borosilicate glass infusion bottle has higher chemical stability requirement as neutral glass because of direct contact with medicines. The prescription composition of the glass is an intrinsic determinant of its chemical stability.
Disclosure of Invention
According to the defects of the prior art, the technical problems to be solved by the invention are as follows: the medium borosilicate glass injection bottle for small-dose injection is provided, and a reasonable preparation formula is adopted, so that low migration of elements such as aluminum, sodium, potassium, calcium and the like is ensured.
The technical scheme adopted by the invention for solving the technical problems is as follows: the medium borosilicate glass injection bottle for small-dose injection is composed of the following raw materials in parts by mass:
the medium borosilicate glass injection bottle for small-dose injection is composed of the following raw materials in parts by mass:
the quartz sand is produced by a quartz sand factory in the Zhongtian mining industry of Fengyang, Anhui.
The alumina is produced by Shandong aluminum industry Co.
The calcined soda is Shandong Haihai chemical group, Inc.
The following is a table listing the contents of the raw materials used:
the production process comprises the following steps:
(1) the production process flow comprises the following steps: raw material-batching-melting-feeding-bottle-making-annealing-checking and packaging-warehousing
(2) Preparing materials: before batching, the water content of raw materials such as quartz sand is measured, various raw materials are weighed strictly according to a batching prescription and are conveyed to a mixer to be mixed for 210 seconds, the uniformity of the batch is not lower than 98 percent, and the water content is not higher than 2 percent.
(3) Melting: the full-cold-top electric melting furnace is adopted, the volatilization of boric anhydride in the glass melting process can be reduced, the molybdenum electrode melting part is adopted for electric heating, the silicon carbide rod of the feeding channel is used for auxiliary heating, and the melting rate reaches 1.4t/m2The electric heating power of the kiln can reach 360 kilowatts.
(4) Feeding: the feed way uses molybdenum electrode heating, silicon carbide rod auxiliary heating, temperature automatic control, and the feeder is domestic C type, and the operation is reliable, uses the stirring rod, increases the degree of consistency of glass industry.
(5) Molding: the equipment for producing the borosilicate glass infusion bottle is a BLH1800 line machine, a spray welding mould is used, the product has high smoothness, and the machine speed for producing 50ml of products is 45 shears/min.
(6) And (3) annealing: the electric heating annealing furnace is used, five groups of temperature control points are arranged, the temperature gradient control is stable, the furnace does not contain harmful gases such as sulfur dioxide and the like, and the environment is not polluted.
The invention has the beneficial effects that:
SiO is reasonably matched in the material formula2、Al2O3、B2O3、Na2The proportion of O and other components ensures that the glass performance reaches the neutral requirement. The gas rate is relatively low, and the mode of cold top melting is adopted, so that the volatilization of raw materials is reduced, and the pollution to the atmosphere is reduced. Cerium oxide is used to replace white arsenic as a clarifier, thereby avoiding toxic components inThe residual in the glass improves the use safety.
Detailed Description
The following further describes embodiments of the present invention:
example 1
A medium borosilicate glass injection bottle for small-dose injection adopts a reasonable preparation formula, and ensures low migration of elements such as aluminum, sodium, potassium, calcium and the like.
The technical scheme adopted by the invention for solving the technical problems is as follows: the medium borosilicate glass injection bottle for small-dose injection is characterized by comprising the following raw materials in parts by mass:
the quartz sand is produced by a quartz sand factory in the Zhongtian mining industry of Fengyang, Anhui.
The alumina is produced by Shandong aluminum industry Co.
The calcined soda is Shandong Haihai chemical group, Inc.
The quality index of the prepared product is as follows:
example 2
A medium borosilicate glass injection bottle for small-dose injection is characterized by comprising the following raw materials in parts by mass:
the quartz sand is produced by a quartz sand factory in the Zhongtian mining industry of Fengyang, Anhui.
The alumina is produced by Shandong aluminum industry Co.
The calcined soda is Shandong Haihai chemical group, Inc.
The quality index of the prepared product is as follows:
example 3
A medium borosilicate glass injection bottle for small-dose injection is characterized by comprising the following raw materials in parts by mass:
the quartz sand is produced by a quartz sand factory in the Zhongtian mining industry of Fengyang, Anhui.
The alumina is produced by Shandong aluminum industry Co.
The calcined soda is Shandong Haihai chemical group, Inc.
The quality index of the prepared product is as follows:
Claims (5)
1. a medium borosilicate glass injection bottle for small-dose injection is characterized by comprising the following raw materials in parts by mass:
2. the medium borosilicate glass injection bottle for small-dose injection according to claim 1, which is composed of the following raw materials in parts by mass:
3. the medium borosilicate glass injection bottle for small dose injection according to claim 1, wherein said quartz sand is produced by a quartz sand factory in the Zhongtian mining industry of Fengyang, Anhui.
4. The medium borosilicate glass injection bottle for small volume injection according to claim 1, wherein said alumina is manufactured by Shandong aluminum industries, Ltd.
5. The medium borosilicate glass injection bottle for small volume injection according to claim 1, wherein said soda ash is Shandong Kaihai chemical group, Ltd.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911331374.0A CN110963708A (en) | 2019-12-21 | 2019-12-21 | Small dose injection is with borosilicate glass injection bottle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911331374.0A CN110963708A (en) | 2019-12-21 | 2019-12-21 | Small dose injection is with borosilicate glass injection bottle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110963708A true CN110963708A (en) | 2020-04-07 |
Family
ID=70035649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911331374.0A Pending CN110963708A (en) | 2019-12-21 | 2019-12-21 | Small dose injection is with borosilicate glass injection bottle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110963708A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112694254A (en) * | 2021-01-04 | 2021-04-23 | 河北光兴半导体技术有限公司 | Medium borosilicate glass composition, medium borosilicate glass, and preparation method and application thereof |
| CN114349338A (en) * | 2021-12-24 | 2022-04-15 | 山东省药用玻璃股份有限公司 | Medium borosilicate glass molding injection bottle |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1155876A (en) * | 1995-04-28 | 1997-07-30 | 伊尔默瑙玻璃技术有限公司 | Borosilicate glass |
| US20070021287A1 (en) * | 2004-04-27 | 2007-01-25 | Hockman John A | Method of manufacturing glass and compositions thereof |
| CN101148317A (en) * | 2007-08-22 | 2008-03-26 | 东营力诺玻璃制品有限责任公司 | Formulation for medicinal neutral boron silicate glass |
| CN101186437A (en) * | 2006-11-17 | 2008-05-28 | 山东省药用玻璃股份有限公司 | Neutral boron silicate glass used for medicinal mold-formed bottle and manufacturing method thereof |
| CN101343143A (en) * | 2008-08-18 | 2009-01-14 | 四川省阆中光明玻璃制品有限公司 | Neutral boron silex glass for mold-formed bottle for storing and freezing biotic product, and method of manufacturing the same |
| CN106277765A (en) * | 2016-08-31 | 2017-01-04 | 山东省药用玻璃股份有限公司 | Brown pharmaceutical glass and preparation method thereof |
-
2019
- 2019-12-21 CN CN201911331374.0A patent/CN110963708A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1155876A (en) * | 1995-04-28 | 1997-07-30 | 伊尔默瑙玻璃技术有限公司 | Borosilicate glass |
| US20070021287A1 (en) * | 2004-04-27 | 2007-01-25 | Hockman John A | Method of manufacturing glass and compositions thereof |
| CN101186437A (en) * | 2006-11-17 | 2008-05-28 | 山东省药用玻璃股份有限公司 | Neutral boron silicate glass used for medicinal mold-formed bottle and manufacturing method thereof |
| CN101148317A (en) * | 2007-08-22 | 2008-03-26 | 东营力诺玻璃制品有限责任公司 | Formulation for medicinal neutral boron silicate glass |
| CN101343143A (en) * | 2008-08-18 | 2009-01-14 | 四川省阆中光明玻璃制品有限公司 | Neutral boron silex glass for mold-formed bottle for storing and freezing biotic product, and method of manufacturing the same |
| CN106277765A (en) * | 2016-08-31 | 2017-01-04 | 山东省药用玻璃股份有限公司 | Brown pharmaceutical glass and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 张云兰等: "《非金属工程材料》", 31 October 1987, 轻工业出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112694254A (en) * | 2021-01-04 | 2021-04-23 | 河北光兴半导体技术有限公司 | Medium borosilicate glass composition, medium borosilicate glass, and preparation method and application thereof |
| CN114349338A (en) * | 2021-12-24 | 2022-04-15 | 山东省药用玻璃股份有限公司 | Medium borosilicate glass molding injection bottle |
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Application publication date: 20200407 |
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