CN110961170A - Sampling receiver for inhalation preparation experiment - Google Patents

Sampling receiver for inhalation preparation experiment Download PDF

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Publication number
CN110961170A
CN110961170A CN201911309867.4A CN201911309867A CN110961170A CN 110961170 A CN110961170 A CN 110961170A CN 201911309867 A CN201911309867 A CN 201911309867A CN 110961170 A CN110961170 A CN 110961170A
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CN
China
Prior art keywords
pipe
tube
inhalation
absorption liquid
sampling receiver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911309867.4A
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Chinese (zh)
Inventor
赵莹
张萌
费洪荣
李炳龙
曲晓兰
肖玉良
韩俊芬
游桂荣
夏志童
陆洪坤
闫福鹏
张丽娜
臧硕
李洪博
迟梦辰
候哲
时宇
卜佳伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong First Medical University and Shandong Academy of Medical Sciences
Original Assignee
Shandong First Medical University and Shandong Academy of Medical Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong First Medical University and Shandong Academy of Medical Sciences filed Critical Shandong First Medical University and Shandong Academy of Medical Sciences
Priority to CN201911309867.4A priority Critical patent/CN110961170A/en
Publication of CN110961170A publication Critical patent/CN110961170A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention relates to an inhalation preparation experiment sampling receiver, which aims to solve the problems that in the existing inhalation preparation sampling process, absorption liquid is easy to spill and the inhalation preparation cannot be uniformly pressed, so that the experimental result is inaccurate; according to the invention, the inhalation preparation directly enters the absorption liquid storage assembly through the inhalation preparation placing structure and the test tube assembly, so that the problems that the absorption liquid is easy to spill and the inhalation preparation cannot be uniformly pressed can be avoided, the absorption effect of the collected liquid is enhanced, and the accuracy of an inhalation preparation experiment is improved.

Description

Sampling receiver for inhalation preparation experiment
Technical Field
The invention relates to the technical field of experimental equipment, in particular to an inhalation preparation experiment sampling receiver.
Background
With global air pollution and environmental deterioration, the morbidity and mortality of asthma is rising year by year. The research and the popularization of asthma treatment medicines can not only lead asthma patients to regain new life and obtain huge social benefits, but also bring great profit margin, and the asthma medicine market is one of ten medicine markets which have the greatest development prospect in twenty years in the future. The inhalation therapy is recommended by the international alliance for asthma (GINA) as the first choice for treating asthma, and the quantitative inhalation aerosols (MDIs) play a significant role in the inhalation therapy due to the advantages of quick response, small dosage, less side effect, safe and convenient use and the like.
The existing sampling method for inhalation preparations is as follows: taking 1 inhalation preparation, shaking thoroughly, removing cap, trying for 5 times, rinsing the mouth with absorbing solution, drying thoroughly, placing upside down in a suitable beaker with a certain amount of absorbing solution added as absorbing solution, immersing the mouth under the liquid level of absorbing solution (at least 25mm), pressing for 10 times (paying attention to 5 seconds interval between each pressing and slowly shaking), taking out, rinsing the inside and outside of the mouth with absorbing solution, combining absorbing solution and washing solution, quantitatively transferring to a measuring flask, diluting with absorbing solution to scale, shaking uniformly, and using as sample solution.
In actual operation, there are the following problems:
1. the requirement on the specialty is high, the inhalation preparation is used as a special preparation, the inspection operation needs professional training, and few experimenters capable of performing the inspection operation are needed;
2. the repeatability is low, and because the force and time requirements of each press are strict and consistent when the preparation is sucked for sampling, the uniform pressing of the preparation is difficult to achieve under the existing conditions, so that the repeatability is high;
3. the accuracy is low, and the preparation that inhales sampling process adopts the beaker to collect, exists the absorption liquid and easily spills and inhale the preparation and can not evenly press, and the accurate collection is hardly caused, causes the inaccurate problem of experimental result.
Disclosure of Invention
(1) Technical problem to be solved
The invention aims to overcome the defects of the prior art, adapt to practical needs, and provide an inhalation preparation experiment sampling receiver, aiming at solving the problems that in the existing inhalation preparation sampling process, a beaker is adopted for collection, absorption liquid is easy to splash out, and the inhalation preparation cannot be uniformly pressed, so that the experiment result is inaccurate.
(2) Technical scheme
In order to realize the purpose of the invention, the technical scheme adopted by the invention is as follows:
an inhalation preparation experiment sampling receiver comprises an inhalation preparation placing structure, a test tube assembly and an absorption liquid storage assembly, wherein the inhalation preparation placing structure is arranged at the upper part of the test tube assembly, and the absorption liquid storage assembly is arranged at the lower part of the test tube assembly;
the inhalation preparation placing structure comprises a holding tube and a connecting tube, wherein the connecting tube is arranged at the lower end of the holding tube in a penetrating way, a placing assembly is arranged in the holding tube, and a first thread groove is formed in the inner wall of the connecting tube;
the test tube assembly comprises a liquid bearing tube and a test tube connecting part, the liquid bearing tube and the test tube connecting part are arranged in a run-through mode, a second thread groove is arranged outside the test tube connecting part, and the second thread groove is in threaded arrangement with the first thread groove;
the subassembly is deposited to absorption liquid includes that absorption liquid deposits pipe, locking cap and leads to the liquid pipe, the locking cap is used for absorption liquid to deposit the fixed seal of managing the opening, lead to the liquid pipe and insert and establish on the locking cap, and the locking cap link up the setting with the inside that absorption liquid deposited the pipe, the locking cap contradicts with the stand pipe and sets up, it extends to in the removal pipe to lead to the liquid pipe.
Further, place the subassembly and include the stand pipe, the lower extreme of stand pipe is provided with the connecting seat, and link up on the connecting seat and seted up the through-hole, the lower extreme of connecting seat is provided with removes the pipe, and removes the pipe activity and peg graft in the fixed intraductal, fixed pipe is fixed to be set up on the interior diapire of connecting pipe, it is provided with supporting spring to remove to twine on the pipe, and supporting spring's both ends are fixed respectively and are set up on the lateral wall that removes the pipe and on the upper end of fixed pipe, the seal groove has been seted up to the inside wall of fixed pipe, and fixed pipe goes up the activity and peg graft and have the closing plate, the closing plate is located the one end setting in the fixed pipe in the seal groove, twine on the closing plate and be provided with sealing spring, and.
Further, a pipe cap is sleeved outside the connecting pipe.
Further, test tube connecting portion overcoat is equipped with the test tube cap.
Furthermore, scales are arranged outside the liquid bearing pipe.
Further, the stand pipe sets up to horn-shaped structure, and the stand pipe matches the setting with the bottle of absorption liquid storage tube.
Further, the sealing plate is provided in a rectangular structure.
Furthermore, a sealing gasket is fixedly sleeved at one end of the sealing plate, which is positioned in the sealing groove.
Furthermore, the cavity of the fixed pipe is of a rectangular structure, and the inner pipe of the fixed pipe and the sealing plate are arranged in a sliding mode on the side close to each other.
Furthermore, the upper end of one section of the sealing plate in the fixed pipe is fixedly provided with a touch rod, and the upper end of the touch rod is provided with a touch block.
Further, the contact block is arranged in a spherical structure.
Has the advantages that:
in the invention, the reagent directly enters the reagent tube through the absorption liquid storage tube, and the problem that the experimental result is inaccurate as the absorption liquid is easy to spill and the absorbed preparation cannot be uniformly pressed in the existing preparation sampling process by using a beaker for collection is solved.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is an exploded view of the structure of the present invention;
FIG. 3 is a schematic view of the placement of an inhalation formulation according to the present invention;
FIG. 4 is a schematic view of a placement module according to the present invention;
FIG. 5 is an enlarged view of the structure A of the present invention.
FIG. 6 is a schematic view of the curvature of the cuvette assembly according to the present invention.
The reference numbers are as follows:
the inhalation preparation placing structure 1, the grip tube 11, the connection tube 12, the cap 13, the placing member 14, the guide tube 141, the connection holder 142, the through hole 143, the moving tube 144, the support spring 145, the fixing tube 146, the reagent flow port 147, the sealing groove 148, the sealing plate 149, the sealing spring 1410, the abutting rod 1411, the abutting block 1412, the cuvette assembly 2, the cuvette holder 21, the cuvette connection section 22, the cuvette cap 23, the absorption liquid storage member 3, the absorption liquid storage tube 31, the fixing cap 32, and the liquid passing tube 33.
Detailed Description
The invention will be further illustrated with reference to the following figures 1 to 5 and examples:
an inhalation preparation experiment sampling receiver comprises an inhalation preparation placing structure 1, a test tube assembly 2 and an absorption liquid storage assembly 3, wherein the test tube assembly 2 is arranged at the lower part of the inhalation preparation placing structure 1, and the absorption liquid storage assembly 3 is arranged at the upper part of the inhalation preparation placing structure 1;
the inhalation preparation placing structure 1 comprises a holding tube 11 and a connecting tube 12, wherein the connecting tube 12 is arranged at the lower end of the holding tube 11 in a penetrating way, specifically, the lower end of the holding tube 11 is connected with one end of the connecting tube 12, the other end of the connecting tube 12 is connected with a tube cap 13, namely, two ends of the connecting tube 12 are respectively connected with the holding tube 11 and the tube cap 13, a placing component 14 is arranged in the holding tube 11, a first thread groove is arranged on the inner wall of the connecting tube 12, the placing component 14 comprises a guide tube 141, a connecting seat 142 is arranged at the lower end of the guide tube 141, a through hole 143 is arranged on the connecting seat 142 in a penetrating way, a moving tube 144 is arranged at the lower end of the connecting seat 142, the moving tube 144 is movably inserted in a fixed tube 146, the fixed tube 146 is fixedly arranged on the inner bottom wall of the connecting tube 12, a supporting spring 145 is wound on the moving tube 144, and two ends of the supporting spring, the lower end of the fixed tube 146 is fixedly arranged on the inner bottom wall of the connecting tube 12, the inner side wall of the fixed tube 146 is provided with a sealing groove 148, the fixed tube 146 is movably inserted with a sealing plate 149, one end of the sealing plate 149, which is positioned in the fixed tube 146, is arranged in the sealing groove 148, the sealing plate 149 is wound with a sealing spring 1410, and two ends of the sealing spring 1410 are respectively and fixedly arranged on the side wall of the sealing plate 149 and the outer side wall of the fixed tube 146;
the test tube assembly 2 comprises a liquid bearing tube 21 and a test tube connecting part 22, the liquid bearing tube 21 and the test tube connecting part 22 are arranged in a penetrating mode, a second thread groove is arranged outside the test tube connecting part 22, and the second thread groove and the first thread groove are in thread arrangement;
as shown in fig. 6, a certain curvature is further provided between the liquid holding tube 21 and the connecting portion 22, so that the liquid holding tube 21 and the connecting portion 22 are not aligned with each other, thereby facilitating the use of the test tube assembly, and the downward curvature between the liquid holding tube 21 and the connecting portion 22 is 15 °, so that the end of the liquid holding tube 21 is slightly bent toward the direction of the inhalation preparation placement structure 1 after the liquid holding tube 21 is installed.
The absorption liquid storage unit 3 comprises an absorption liquid storage tube 31, a fixing cap 32 and a liquid passing tube 33, the fixing cap 32 is used for fixing and sealing the opening part of the absorption liquid storage tube 31, the liquid passing tube 33 is inserted on the fixing cap 32, the fixing cap 32 is disposed to penetrate the inside of the absorption liquid storage tube 31, the fixing cap 32 is disposed to abut against the guide tube 141, and the liquid passing tube 33 is extended into the moving tube 144, in the present invention, the reagent directly enters the reagent tube through the absorption liquid storage tube, aiming at solving the problems that the prior sampling process of the absorbed preparation adopts a beaker for collection, the absorption liquid is easy to spill out and the absorbed preparation can not be uniformly pressed, so that the experimental result is inaccurate, in addition, the structure is small and exquisite, the storage and taking are easy, and meanwhile, the shape of the inhalation preparation placing structure 1 is designed to be convenient to hold, so that the effects of time and labor saving and accurate experimental operation can be achieved during working.
In this embodiment, a liquid receiving tube 21 is provided for collecting the reagent.
At ordinary times, be equipped with test tube cap 23 on the test tube connecting portion 22 of holding liquid pipe 21 tip for the protection holds liquid pipe 21, when holding liquid pipe 21 not using, can avoid holding liquid pipe 21 to be contaminated simultaneously, the second thread groove that sets up on test tube connecting portion 22, the first thread groove that sets up on the inner wall of connecting pipe 12, through the screw thread accordant connection of first thread groove and second thread groove, the realization is inhaled the preparation and is placed structure 1 and test tube subassembly 2 stable fixed.
When the absorption liquid storage component 3 and the inhalation preparation placement structure 1 are placed, the fixing cap 32 abuts against the guide pipe 141, the liquid flowing pipe 33 extends into the moving pipe 144, in a specific working process, the absorption liquid storage pipe 31 is pressed, the downward movement of the absorption liquid storage pipe 31 can drive the combination of the connecting seat 142 and the moving pipe 144 to move downwards, the movement of the moving pipe 144 can abut against the sealing plate 149 to move out of the sealing groove 148, so that reagents in the absorption liquid storage pipe 31 and the liquid bearing pipe 21 can be communicated with each other, and the collection of the reagents is completed.
In this embodiment, the connection tube 12 is externally sleeved with the tube cap 13, so that the connection tube 12 can be sealed, and the arrangement of the tube cap 13 can prevent the reagent from scattering and can also be used for dust prevention.
In this embodiment, test tube connecting portion 22 overcoat is equipped with test tube cap 23, and the setting of test tube cap 23 both can prevent that reagent from scattering, can be used for dustproof effect again.
In this embodiment, the liquid bearing tube 21 is provided with scales for accurate liquid taking.
In this embodiment, the guide tube 141 is set to be a horn-shaped structure, and the guide tube 141 is matched with the bottle of the absorption liquid storage tube 31, so that the absorption liquid storage tube 31 can be effectively supported, and the absorption liquid storage tube 31 can be prevented from accurately entering the guide tube 141.
In this embodiment, the sealing plate 149 is set to a rectangular structure, the sealing plate 149 is located at one end of the sealing groove 148 and fixedly sleeved with a sealing gasket, the cavity of the fixed tube 146 is set to be a rectangular structure, and the inner tube of the fixed tube 146 and one side of the sealing plate 149 close to each other are slidably arranged, so that a better sealing effect can be achieved.
In this embodiment, a contact rod 1411 is fixedly disposed at an upper end of a section of the sealing plate 149 located in the fixing tube 146, an abutting block 1412 is disposed at an upper end of the abutting rod 1411, the abutting block 1412 is a spherical structure, and the abutting rod 1411 and the abutting block 1412 are disposed to ensure that the moving tube 144 can accurately abut against the sealing plate 149.
A support spring 145 and a sealing spring 1410, which are used to restore the device to its original position when the device is out of service.
The invention has the beneficial effects that:
in the invention, the reagent directly enters the reagent tube through the absorption liquid storage tube, and the problem that the experimental result is inaccurate as the absorption liquid is easy to spill and the absorbed preparation cannot be uniformly pressed in the existing preparation sampling process by using a beaker for collection is solved.
Of course, the above description is not limited to the above examples, and the undescribed technical features of the present invention can be implemented by or using the prior art, and will not be described herein again; the above embodiments and drawings are only for illustrating the technical solutions of the present invention and not for limiting the present invention, and the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that changes, modifications, additions or substitutions within the spirit and scope of the present invention may be made by those skilled in the art without departing from the spirit of the present invention, and shall also fall within the scope of the claims of the present invention.

Claims (10)

1. An inhalation preparation experiment sampling receiver comprises an inhalation preparation placing structure, a test tube assembly and an absorption liquid storage assembly, and is characterized in that the inhalation preparation placing structure is arranged at the upper part of the test tube assembly, and the absorption liquid storage assembly is arranged at the lower part of the test tube assembly;
the inhalation preparation placing structure comprises a holding tube and a connecting tube, wherein the connecting tube is arranged at the lower end of the holding tube in a penetrating way, a placing assembly is arranged in the holding tube, and a first thread groove is formed in the inner wall of the connecting tube;
the test tube assembly comprises a liquid bearing tube and a test tube connecting part, the liquid bearing tube and the test tube connecting part are arranged in a run-through mode, a second thread groove is arranged outside the test tube connecting part, and the second thread groove is in threaded arrangement with the first thread groove;
the subassembly is deposited to absorption liquid includes that absorption liquid deposits pipe, locking cap and leads to the liquid pipe, the locking cap is used for absorption liquid to deposit the fixed seal of managing the opening, lead to the liquid pipe and insert and establish on the locking cap, and the locking cap link up the setting with the inside that absorption liquid deposited the pipe, the locking cap contradicts with the stand pipe and sets up, it extends to in the removal pipe to lead to the liquid pipe.
2. An inhalation formulation test sampling receiver as claimed in claim 1, wherein: the placing component comprises a guide pipe, the lower end of the guide pipe is provided with a connecting seat, a through hole is formed in the connecting seat in a penetrating mode, the lower end of the connecting seat is provided with a moving pipe, the moving pipe is movably inserted into a fixed pipe, the fixed pipe is fixedly arranged on the inner bottom wall of the connecting pipe, a supporting spring is wound on the moving pipe, the two ends of the supporting spring are fixedly arranged on the outer side wall of the moving pipe and the upper end of the fixed pipe respectively, the inner side wall of the fixed pipe is provided with a sealing groove, a sealing plate is movably inserted into the fixed pipe, one end, located in the fixed pipe, of the sealing plate is arranged in the sealing groove, a sealing spring is wound on the sealing plate, and the two ends of the sealing spring are fixedly arranged on the side wall of the.
3. An inhalation formulation test sampling receiver as claimed in claim 1, wherein: the connecting pipe overcoat is equipped with the tube cap, test tube connecting portion overcoat is equipped with the test tube cap.
4. An inhalation formulation test sampling receiver as claimed in claim 1, wherein: scales are arranged outside the liquid bearing pipe.
5. An inhalation formulation test sampling receiver as claimed in claim 2, wherein: the stand pipe sets up to horn-shaped structure, and the stand pipe and the bottle of absorption liquid storage tube match the setting.
6. An inhalation formulation test sampling receiver as claimed in claim 2, wherein: the sealing plate is arranged to be of a rectangular structure.
7. An inhalation formulation test sampling receiver as claimed in claim 2, wherein: and a sealing gasket is fixedly sleeved at one end of the sealing plate, which is positioned in the sealing groove.
8. An inhalation formulation test sampling receiver as claimed in claim 2, wherein: the cavity of the fixed pipe is of a rectangular structure, and the inner pipe of the fixed pipe and one side, close to the sealing plate, of the sealing plate are arranged in a sliding mode.
9. An inhalation formulation test sampling receiver as claimed in claim 2, wherein: the upper end of one section of the sealing plate in the fixed pipe is fixedly provided with a touch rod, and the upper end of the touch rod is provided with a touch block.
10. An inhalation formulation test sampling receiver as claimed in claim 9, wherein: the contact block is set to be a spherical structure.
CN201911309867.4A 2019-12-18 2019-12-18 Sampling receiver for inhalation preparation experiment Pending CN110961170A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911309867.4A CN110961170A (en) 2019-12-18 2019-12-18 Sampling receiver for inhalation preparation experiment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911309867.4A CN110961170A (en) 2019-12-18 2019-12-18 Sampling receiver for inhalation preparation experiment

Publications (1)

Publication Number Publication Date
CN110961170A true CN110961170A (en) 2020-04-07

Family

ID=70034907

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911309867.4A Pending CN110961170A (en) 2019-12-18 2019-12-18 Sampling receiver for inhalation preparation experiment

Country Status (1)

Country Link
CN (1) CN110961170A (en)

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