CN110960487A - Propofol injection for pets - Google Patents
Propofol injection for pets Download PDFInfo
- Publication number
- CN110960487A CN110960487A CN201911382560.7A CN201911382560A CN110960487A CN 110960487 A CN110960487 A CN 110960487A CN 201911382560 A CN201911382560 A CN 201911382560A CN 110960487 A CN110960487 A CN 110960487A
- Authority
- CN
- China
- Prior art keywords
- propofol
- injection
- pets
- anesthetic
- pet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a propofol injection for pets, and relates to the technical field of injection medicaments, wherein the propofol content in the propofol injection is 8-14 mg/ml, the propofol injection comprises propofol, oil for injection, a regulator and water for injection, and the propofol injection is in a sealed tank shape. The injection type pet anesthetic disclosed by the invention has the advantages that the anesthetic speed for pets is improved in an injection mode, the effect is fast, the anesthetic maintaining time of the pets is controlled by controlling the content of propofol, the recovery effect of the waking body of the pets is better after the anesthetic maintaining time of the pets is over, the propofol is used for pet anesthesia, the anesthetic efficiency for the pets is higher in use, and the influence on the body function of the pets is small.
Description
Technical Field
The invention relates to the technical field of injection medicaments, in particular to a propofol injection for pets.
Background
The pet hospital among the prior art is when carrying out the operation treatment to the pet, in order to improve the operation treatment to the pet and avoid the pet to cause the injury to the veterinarian personnel, generally can anaesthetize it before the pet operation, and most pet anaesthesia among the prior art is in order to furthest reduce the toxicity and the side effect of narcotic, enlarge its safety and application range, single anaesthetic is rarely used now, generally adopt compound anaesthetic of animal to carry out compound anaesthesia to the animal more, but this kind of mode reaches four hours promptly to the first anaesthesia maintenance time of pet, it is relatively poor to the safe handling control ability of pet, because of the anesthesia process degree is too deep, it is poor to appear the recovery state after the pet awakens easily, influence the bodily function of pet, it is poor to lead to the pet to awaken the back body ability recovery effect that awakens.
Therefore, the invention of a propofol injection for pets is needed to solve the problems.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a propofol injection for pets, and solves the problems that the conventional anesthetic injection for pets has long anesthetic time, poor safety control capability on pets and poor recovery state after the pets awaken.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: the propofol injection for pets contains 8-14 mg/ml of propofol.
Optionally, the content of propofol in the propofol injection is 15 mg/ml-24 mg/ml.
Optionally, the content of propofol in the propofol injection is 25 mg/ml-35 mg/ml.
Optionally, the content of propofol in the propofol injection is 37 mg/ml-50 mg/ml.
Preferably, the propofol injection comprises propofol, oil for injection, a regulator and water for injection.
Preferably, the propofol injection is in a sealed pot shape.
(III) advantageous effects
The invention provides a propofol injection for pets, which has the following beneficial effects:
(1) the injection can improve the anesthesia speed of the pet, has quick response, controls the anesthesia maintenance time of the pet by controlling the content of propofol, and has better recovery effect when the anesthesia maintenance time of the pet is over.
(2) The invention uses the propofol for pet anesthesia, has higher efficiency for pet anesthesia in use, and has little influence on pet body function.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
the propofol injection for pets contains 9mg/ml of propofol.
Example 2:
the propofol injection for pets contains 22mg/ml of propofol.
Example 3:
the propofol injection for pets contains 31mg/ml of propofol.
Example 4:
the propofol injection for pets contains 48mg/ml of propofol.
As a preferred technical scheme of the invention:
the propofol injection comprises propofol, oil for injection, a regulator and water for injection.
As a preferred technical scheme of the invention:
the propofol injection is in a sealed pot shape.
Table 1 shows experimental data of propofol injection of the present invention
| Propofol content in injection | Time to onset of anesthesia | Maintenance time | Reaction after recovery | |
| Example 1 | 9mg/ml | 70s | 8min | Stabilization |
| Example 2 | 22mg/ml | 54s | 17min | Stabilization |
| Example 3 | 31mg/ml | 43s | 22min | Is more stable |
| Example 4 | 48mg/ml | 27s | 28min | Is more stable |
TABLE 1
The injection anesthesia can be carried out on the pet by the four groups of embodiments, wherein the anesthesia speed of the fourth group of embodiments is the fastest, and the anesthesia treatment effect of the second group of embodiments on the pet is the best.
It is noted that in the present disclosure, unless otherwise explicitly specified or limited, a first feature "on" or "under" a second feature may be directly contacted with the first and second features, or indirectly contacted with the first and second features through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (6)
1. The propofol injection for pets is characterized in that the propofol content in the propofol injection is 8 mg/ml-14 mg/ml.
2. The propofol injection for pets, according to claim 1, wherein: the content of propofol in the propofol injection is 15 mg/ml-24 mg/ml.
3. The propofol injection for pets, according to claim 1, wherein: the content of propofol in the propofol injection is 25 mg/ml-35 mg/ml.
4. The propofol injection for pets, according to claim 1, wherein: the content of propofol in the propofol injection is 37 mg/ml-50 mg/ml.
5. The propofol injection for pets, according to claim 1, wherein: the propofol injection comprises propofol, oil for injection, a regulator and water for injection.
6. The propofol injection for pets, according to claim 1, wherein: the propofol injection is in a sealed pot shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911382560.7A CN110960487A (en) | 2019-12-27 | 2019-12-27 | Propofol injection for pets |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911382560.7A CN110960487A (en) | 2019-12-27 | 2019-12-27 | Propofol injection for pets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110960487A true CN110960487A (en) | 2020-04-07 |
Family
ID=70037064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911382560.7A Pending CN110960487A (en) | 2019-12-27 | 2019-12-27 | Propofol injection for pets |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110960487A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045042B (en) * | 2006-03-30 | 2010-09-22 | 上海医药工业研究院 | Propofol injection and its preparing method |
| CN102805728A (en) * | 2012-08-22 | 2012-12-05 | 南京正大天晴制药有限公司 | Propofol fat emulsion injection and preparation method thereof |
| CN102871964A (en) * | 2012-10-29 | 2013-01-16 | 江苏盈科生物制药有限公司 | Stable and efficient propofol middle/long-chain fat emulsion injection and preparation method thereof |
| WO2018225229A1 (en) * | 2017-06-08 | 2018-12-13 | Terumo Kabushiki Kaisha | Parenteral aqueous pharmaceutical composition |
| CN109692154A (en) * | 2017-10-24 | 2019-04-30 | 扬子江药业集团有限公司 | In a kind of Propofol/preparation method of long chain fat emulsion injection |
-
2019
- 2019-12-27 CN CN201911382560.7A patent/CN110960487A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045042B (en) * | 2006-03-30 | 2010-09-22 | 上海医药工业研究院 | Propofol injection and its preparing method |
| CN102805728A (en) * | 2012-08-22 | 2012-12-05 | 南京正大天晴制药有限公司 | Propofol fat emulsion injection and preparation method thereof |
| CN102871964A (en) * | 2012-10-29 | 2013-01-16 | 江苏盈科生物制药有限公司 | Stable and efficient propofol middle/long-chain fat emulsion injection and preparation method thereof |
| WO2018225229A1 (en) * | 2017-06-08 | 2018-12-13 | Terumo Kabushiki Kaisha | Parenteral aqueous pharmaceutical composition |
| CN109692154A (en) * | 2017-10-24 | 2019-04-30 | 扬子江药业集团有限公司 | In a kind of Propofol/preparation method of long chain fat emulsion injection |
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200407 |