CN110934743B - Method for manufacturing multi-cavity eyedrop bottle, application and using method - Google Patents
Method for manufacturing multi-cavity eyedrop bottle, application and using method Download PDFInfo
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- CN110934743B CN110934743B CN201911414486.2A CN201911414486A CN110934743B CN 110934743 B CN110934743 B CN 110934743B CN 201911414486 A CN201911414486 A CN 201911414486A CN 110934743 B CN110934743 B CN 110934743B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
- B29C49/02—Combined blow-moulding and manufacture of the preform or the parison
- B29C49/06—Injection blow-moulding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
- B29C49/02—Combined blow-moulding and manufacture of the preform or the parison
- B29C2049/023—Combined blow-moulding and manufacture of the preform or the parison using inherent heat of the preform, i.e. 1 step blow moulding
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Abstract
The invention discloses a method for manufacturing a multi-cavity eyedrop bottle, which comprises the following steps: a. designing and manufacturing a mould with each independent bottle body of the multi-cavity eyedrop bottle; b. melting the medical plastic particles by an injection molding technology and injecting the melted medical plastic particles into a bottle blank; c. respectively placing the bottle blanks in the mold of each independent bottle body to be molded into independent bottle bodies by blow molding; d. moving the formed independent bottle body to the air for natural cooling; e. removing burrs on the independent bottle body to obtain a finished independent bottle body; two or more independent bottles are combined into a multi-cavity eyedrop bottle with the same and level bottle opening direction. Adopt above-mentioned technical scheme, connect into a multicavity eyedrop bottle through making a plurality of independent bottles, can make eyedrop independently save in the independent bottle of difference, avoid its different composition to cause physics and chemical reaction in the coexistence same bottle, influence its treatment, this multicavity eyedrop bottle simple structure, easy equipment production, the practicality is very strong moreover.
Description
Technical Field
The invention relates to the technical field related to multi-cavity eyedrop bottles, in particular to a manufacturing method, application and using method of the multi-cavity eyedrop bottle.
Background
Eye drops are one of the most common and commonly used pharmaceutical dosage forms for treating ophthalmic diseases at present, and the eye drops can play a direct treatment role for many ophthalmic diseases at present. With the development of society and the advancement of technology, informatization and intelligence will permeate every corner of our lives and works, and eyes and vision are the most important ways to obtain information. The eye drop is an essential medicine for treating eye diseases and also an important means for preventing and protecting the eye diseases.
The existing bottles for containing eye drop are all in a single-cavity structure, and one eye drop bottle can only contain one eye drop or one compound eye drop. If one eyedrop bottle contains a plurality of eyedrops, the eyedrops are composed of a plurality of components, so that physical and chemical reactions can occur, the treatment effect is influenced, and even serious adverse effects can be caused. But it is clinically very desirable to drop multiple eye drops simultaneously. Therefore, the single-chamber eyedrop bottle cannot meet the clinical use requirement. How to produce a multi-cavity eyedrop bottle solves the problems that the existing eyedrop bottle has the defects and needs to be solved urgently.
Disclosure of Invention
The invention aims to provide a manufacturing method, application and using method of a multi-cavity eyedrop bottle.
The technical scheme adopted by the invention for solving the technical problem is as follows:
in accordance with one aspect of the present invention, a method of manufacturing a multi-chamber eyedrop bottle is provided, comprising the steps of:
a. designing and manufacturing a mould with each independent bottle body of the multi-cavity eyedrop bottle;
b. melting the medical plastic particles by an injection molding technology and injecting the medical plastic particles into a bottle blank;
c. respectively placing the bottle blanks in the mold of each independent bottle body to be molded into independent bottle bodies by blow molding;
d. moving the formed independent bottle body to the air for natural cooling;
e. removing burrs on the independent bottle body to obtain a finished independent bottle body;
two or more independent bottles are combined into a multi-cavity eyedrop bottle with the same and level bottle opening direction.
Adopt above-mentioned technical scheme, connect into a multicavity eye drop bottle through making a plurality of independent bottles, can make eye drop independently save in the independent bottle of difference, avoid causing physics and chemical reaction in the coexistent same bottle of its different compositions, influence its treatment, this multicavity eye drop bottle simple structure, easy equipment production, the practicality is very strong moreover.
In order to better solve the technical defects, the invention also has a better technical scheme that:
in some embodiments, when the multi-chamber eyedrop bottle is comprised of two separate bodies, each separate body has a flat surface with a uniform shape, wherein the flat surface of one separate body has a boss, the flat surface of the other separate body has a groove matching the boss, and the two separate bodies are joined into a bottle by engaging the boss with the groove.
When the multi-cavity eyedrop bottle consists of three or more independent bottles, each independent bottle is provided with two intersecting planes with the same shape, one of the planes is provided with a boss, the other plane is provided with a groove matched with the boss, and the bosses and the grooves between the independent bottles are mutually clamped, so that the required multi-cavity eyedrop bottle is formed.
From this, can tear independent bottle apart, carry out eye drop alone, can satisfy different user demands.
In some embodiments, each individual bottle body has a section of threads on the outside of the bottle neck, and when the individual bottle bodies are connected together, the threads on the bottle neck are spliced into an external thread that is in mating connection with the internal thread of the bottle cap.
Therefore, the bottle mouth is flush, and the dripping liquid medicine can be guaranteed to be converged to form one drop.
In some embodiments, the surfaces of the independent bottle bodies are coated with glue and then are clamped to form the multi-cavity eyedrop bottle; the combination process can be completed by mechanization and automation.
From this, can prevent to carry out the split after independent bottle makes up into a multicavity bottle, satisfy different user demands.
According to another aspect of the present invention, a multi-chamber eyedrop bottle is provided for use with individual bottles for holding eyedrops including, but not limited to, antibiotics, antivirals, antianaphylactics, mydriasis, antiglaucoma, and dry eye treatments.
In some embodiments, the individual vials are used to contain an ophthalmic solution for antibiotics including, but not limited to, tobramycin and one or both of ofloxacin, rifampin, chloramphenicol, lincomycin, neomycin, gentamicin.
In some embodiments, the individual vials are used to contain antiviral eye drops including, but not limited to, ribavirin and one or both of acyclovir and ganciclovir.
In some embodiments, the individual vials are used to contain anti-allergic eye drops including, but not limited to, one or two or three of azelastine and fluorometholone, pranoprofen, diclofenac, dexamethasone, prednisolone, cromolyn sodium, cyclosporine a, emedastine.
In some embodiments, the individual vials are used to hold mydriatic eye drops including, but not limited to, atropine and sodium hyaluronate or tropicamide and one or both of epinephrine and norepinephrine.
In some embodiments, the individual vials are used to contain anti-glaucoma eye drops including, but not limited to, timolol and one or both of travoprost, brinzolamide, sodium hyaluronate, or 50% glucose and sodium hyaluronate; or pilocarpine, brinzolamide and/or sodium hyaluronate.
In some embodiments, the individual vials are used to contain eye drops for dry eye treatment including, but not limited to, sodium hyaluronate, polyethylene glycol, and the like.
Adopt above-mentioned technical scheme, through the liquid medicine of the different compositions of packing into in each independent bottle to correspond different ophthalmocaces, satisfy different patients' treatment needs, simultaneously, can avoid its different compositions to coexist and cause physics and chemical reaction in the same bottle, influence its treatment.
In accordance with yet another aspect of the present invention, a method of using a multi-chamber eyedrop bottle is provided, comprising the steps of:
a. the human body lies flat and opens eyes, or the human body stands or sits and lifts up and opens eyes, so that the eyeball keeps an angle of 0-20 degrees with the horizontal, or the eye drop is carried out according to the eye drop specification or the doctor's advice;
b. the outer side wall of each independent chamber of the multi-chamber eyedrop bottle is respectively pinched;
c. the multi-cavity eyedrop bottle is moved to the position above the eyeball, the bottle mouth of the multi-cavity eyedrop bottle faces downwards and keeps a distance of 1-1.8 cm with the eyeball, and meanwhile, the outer side wall of the multi-cavity eyedrop bottle is uniformly and forcibly squeezed, so that eyedrop in each cavity is simultaneously squeezed out and converged into a drop to be dripped onto the eyeball.
In some embodiments, when a multi-chamber eyedrop bottle requires one of the individual bottle bodies to drip eyedrop, the outer side wall of the individual bottle body is pressed with force, so that the eyedrop in the individual bottle body is squeezed out and forms a drop which is dripped onto the eyeball.
In some embodiments, when the multi-chamber eyedrop bottle requires two of the independent bottle bodies to drip eyedrop, the outer side walls of the two independent bottle bodies are pressed with force, so that the eyedrop in the two independent bottle bodies is squeezed out and converged into one drop to be dripped onto the eyeball.
In some embodiments, the multi-chamber eyedrop bottle can be uniformly forced to squeeze out the eye drops by a mechanical gripper operation that simulates a human finger.
By adopting the technical scheme, when the multi-cavity eye drop bottle is required to drip eye drops, the method can ensure that the eye drops with almost the same dosage are extruded in each independent bottle body of the multi-cavity eye drop bottle, thereby ensuring the optimal treatment effect.
Drawings
FIG. 1 is a schematic diagram illustrating a multi-chamber eyedrop bottle having two separate bodies according to a method of manufacturing the multi-chamber eyedrop bottle in accordance with one embodiment of the present invention;
FIG. 2 is an exploded view of the multi-chamber eyedrop bottle of FIG. 1;
FIG. 3 is a schematic view showing a multi-chamber eyedrop bottle having three independent bodies manufactured according to a method of manufacturing the multi-chamber eyedrop bottle;
figure 4 is an exploded view of the multi-chamber eyedrop bottle of figure 3.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer and clearer, the present invention is further described in detail below with reference to the accompanying drawings.
The invention provides a method for manufacturing a multi-cavity eyedrop bottle, which comprises the following steps:
a. designing and manufacturing a mould of each independent bottle body of the multi-cavity eye drop bottle;
b. melting the medical plastic particles by an injection molding technology and injecting the melted medical plastic particles into a bottle blank;
c. respectively placing the bottle blanks in the mold of each independent bottle body to be blow molded into independent bottle bodies;
d. moving the formed independent bottle body to the air for natural cooling;
e. removing burrs on the independent bottle body to obtain a finished independent bottle body;
two or more independent bottles are combined into a multi-cavity eyedrop bottle with the same and level bottle opening direction.
Wherein, when multicavity eye drops bottle includes two independent bottles, then the preparation has the mould of two independent bottles, when multicavity eye drops bottle includes three independent bottle, then the preparation has the mould of three independent bottle, when multicavity eye drops bottle includes four independent bottles, then the preparation has the mould of four independent bottles.
When the multi-cavity eyedrop bottle consists of two independent bottles, each independent bottle is provided with a plane with the same shape, a boss is arranged on the plane of one independent bottle, a groove matched with the boss is arranged on the plane of the other independent bottle, and the two independent bottles are connected with the groove in a clamping mode through the bosses on the two independent bottles to form the multi-cavity eyedrop bottle.
Referring to fig. 1 and 2, when the multi-chamber eyedrop bottle 1 is composed of a first independent bottle body 2 and a second independent bottle body 3, the first independent bottle body 2 and the second independent bottle body 3 are respectively provided with a first plane 21 and a second plane 31, the first plane 21 and the second plane 31 are consistent in shape, wherein, the first plane 21 is provided with a boss 22, the second plane 31 is provided with a groove 32 matched with the boss 22, the outer sides of the bottle necks of the first independent bottle body 2 and the second independent bottle body 3 are respectively provided with a first screw tooth 23 and a second screw tooth 33, when the first independent bottle body 2 and the second independent bottle body 3 are combined together by the joint of the boss 22 and the groove 32, the bottle mouths of the first independent bottle body 2 and the second independent bottle body 3 are consistent and level, the first thread 23 and the second thread 33 on the bottle neck are spliced into an external thread 4 which is matched and connected with the internal thread of the bottle cap.
When the multicavity eye drop bottle includes that three and above independent bottle constitutes, then all have two planes that intersect and the shape is unanimous on every independent bottle, the boss has on one of them plane, have the recess that matches with the boss on another plane, the bottleneck outside of each independent bottle has one section screw thread, when three and above independent bottle passes through boss and recess joint combination on it together, the bottleneck direction of each independent bottle is unanimous and the parallel and level, the screw thread on the bottleneck splices into an external screw thread with the internal thread accordant connection of bottle lid.
Referring to fig. 3 and 4, when the multi-chamber eyedrop bottle 1 includes a first independent bottle body 2, a second independent bottle body 3, and a third independent bottle body 4, the first independent bottle body 2, the second independent bottle body 3, and the third independent bottle body 4 have two planes which are intersected and have the same shape; in two planes on the independent bottle body 2, one plane is provided with a boss 21, and the other plane is provided with a groove 22; in two planes on the second independent bottle body 3, one plane is provided with a second boss, and the other plane is provided with a second groove; in two planes on the third independent bottle body 4, one plane is provided with a third boss, and the other plane is provided with a third groove; independent bottle 2, No. two independent bottle 3 and No. three independent bottle 4's bottleneck outside has a screw 23 respectively, No. two screw 33 and No. three screw 43, a boss 21 on independent bottle 2 and No. two recess joint on No. two bottle 3, No. two recesses on No. two bottle 3 and No. three boss joint on No. three bottle 4, when No. three boss on No. three bottle 4 and a recess 22 joint combination on No. 2 were in the same place, independent bottle 2, No. two independent bottle 3 and No. three independent bottle 4 bottleneck direction unanimity and parallel and level, No. one screw 23, No. two screw 33 and No. three screw 43 splice into an external screw thread with the internal thread accordant connection of bottle lid.
When the multi-cavity eyedrop bottle comprises four independent bottle bodies and more independent bottle bodies, the combination mode of the multi-cavity eyedrop bottle is the same as that of the multi-cavity eyedrop bottle comprising three independent bottle bodies, and redundant description is omitted here.
In some embodiments, after glue is smeared on the plane of the independent bottle body, the lug boss on the independent bottle body is clamped with the groove to form a multi-cavity eyedrop bottle; the combination process can be completed by mechanization and automation.
The invention provides application of a multi-cavity eyedrop bottle, and an independent bottle body of the multi-cavity eyedrop bottle can be used for containing eyedrops including but not limited to antibiotics, antivirus, antiallergic, mydriasis, glaucoma and dry eye treatment.
The independent bottle body is used for containing antibiotic eye drops including tobramycin and one of ofloxacin, rifampin, chloramphenicol, lincomycin, neomycin and gentamicin. When the multi-cavity eyedrop bottle comprises two independent bottle bodies, one independent bottle body contains tobramycin, and the other bottle body contains one of ofloxacin, rifampicin, chloramphenicol, lincomycin, neomycin and gentamicin.
The independent bottle body is used for containing antiviral liquid medicine including ribavirin, acyclovir and ganciclovir. When the multi-chamber eyedrop bottle comprises two separate bottles, one of the separate bottles contains ribavirin and the other contains one of acyclovir and ganciclovir.
In some embodiments, the independent bottle is used for containing an antiallergic liquid medicine, including one of azelastine and fluorometholone, pranoprofen, diclofenac sodium, dexamethasone, prednisolone, cromolyn sodium, cyclosporine a, and emedastine. When the multi-cavity eyedrop bottle comprises two independent bottle bodies, one independent bottle body is filled with azelastine, and the other independent bottle body is filled with one of fluorometholone, pranoprofen, diclofenac, dexamethasone, prednisolone, cromolyn sodium, cyclosporine A and emedastine.
In some embodiments, the individual vials are used to hold mydriatic eye drops comprising atropine and sodium hyaluronate or tropicamide and one of epinephrine and norepinephrine. When the multi-cavity eyedrop bottle comprises two independent bottle bodies, one independent bottle body contains atropine, and the other independent bottle body contains sodium hyaluronate; when the multi-chamber eyedrop bottle comprises two separate bodies, one of the separate bodies contains tropicamide and the other contains one of epinephrine or norepinephrine.
The independent bottle body is used for containing anti-glaucoma liquid medicine which comprises timolol and one of travoprost, brinzolamide and sodium hyaluronate, or 50% of glucose and sodium hyaluronate, or pilocarpine, brinzolamide and sodium hyaluronate. When the multi-cavity eyedrop bottle comprises two independent bottle bodies, one independent bottle body is filled with timolol liquid medicine, and the other bottle body is filled with one liquid medicine of travoprost and brinzolamide; or one contains 50% glucose and the other contains sodium hyaluronate; or one contains pilocarpine and the other contains brinzolamide.
When the multi-cavity eyedrop bottle comprises three independent bottle bodies, any three medicine combinations of tobramycin, ofloxacin, rifampicin, chloramphenicol, lincomycin, neomycin and gentamicin are respectively contained in the three independent bottle bodies; or ribavirin, ganciclovir and acyclovir; or timolol, travoprost and brinzolamide; or pilocarpine, brinzolamide and sodium hyaluronate; or any three of azelastine, fluorometholone, pranoprofen, diclofenac sodium, dexamethasone, prednisolone, cromolyn sodium, cyclosporine and emedastine.
When the multi-cavity eyedrop bottle comprises four independent bottle bodies, the four independent bottle bodies are respectively filled with azelastine, fluorometholone, pranoprofen and cyclosporine.
The invention provides a using method of a multi-cavity eyedrop bottle, which comprises the following steps:
a. the human body lies flat and opens eyes, or stands on the back and opens eyes, so that the eyeballs keep an angle of 0-20 degrees with the horizontal plane; or according to eye drop instructions or medical advice;
b. the outer side wall of each independent chamber of the multi-chamber eyedrop bottle is respectively pinched;
c. and moving the multi-cavity eyedrop bottle above the eyeball, wherein the bottle mouth of the multi-cavity eyedrop bottle faces downwards and keeps a distance of 1-1.8 cm from the eyeball, and simultaneously, forcibly extruding the outer side wall of the multi-cavity eyedrop bottle, so that eyedrop in each cavity is extruded out simultaneously and converged into one drop to be dripped onto the eyeball.
The outer side wall of each independent cavity of the multi-cavity eyedrop bottle is held by fingers in a matched mode, and the outer side wall of each independent cavity of the multi-cavity eyedrop bottle can be clamped by other auxiliary tools in a matched mode.
Specifically, when the multi-cavity eyedrop bottle comprises two independent bottle bodies, the middle parts of the outer side walls of the two independent bottle bodies are held between the right hand thumb or the left hand thumb and one or two or three of the index finger, the middle finger, the ring finger and the little finger in a matched mode and moved to the upper portion of the eyeball, the bottle opening of the multi-cavity eyedrop bottle faces downwards and keeps a distance of 1-1.8 cm from the eyeball, and the thumb and one or two or three of the index finger, the middle finger, the ring finger and the little finger are pressed forcibly at the same time, so that eyedrop in the two independent bottle bodies is extruded out at the same time and converged into one drop to be dripped onto the eyeball.
When the multi-cavity eyedrop bottle comprises three independent bottle bodies, three fingers of five fingers of a right hand or a left hand are matched to pinch the middle parts of the outer side walls of the three independent bottle bodies and move to the upper part of an eyeball, a bottle opening of the multi-cavity eyedrop bottle faces downwards and keeps a distance of 1-1.8 cm with the eyeball, and three fingers of the five fingers are simultaneously and forcefully extruded, so that eyedrop in the three independent bottle bodies is simultaneously extruded and converged into one drop to be dripped onto the eyeball.
When the multi-cavity eyedrop bottle comprises four independent bottle bodies, the middle parts of the outer side walls of the four independent cavities are pinched by the thumb, the index finger, the middle finger and the ring finger of the right hand or the left hand in a matching mode and are moved to the upper portion of the eyeball, the bottle opening of the multi-cavity eyedrop bottle faces downwards and keeps a distance of 1-1.8 cm with the eyeball, and the thumb, the index finger, the middle finger and the ring finger press the four-cavity eyedrop bottle forcibly at the same time, so that eyedrops in the four independent bottle bodies are extruded at the same time and converged into one drop to be dripped onto the eyeball.
In some embodiments, when a multi-cavity eyedrop bottle requires one of the independent bottle bodies to drip eyedrop, the outer side wall of the independent bottle body is pressed with force, so that the eyedrop in the independent bottle body is squeezed out and forms a drop which is dripped on an eyeball; the multi-cavity eyedrop bottle dropping method is suitable for a multi-cavity eyedrop bottle with three independent bottle bodies, a thumb is in contact with the middle of one outer side wall of the three independent bottle bodies, one or two or three of an index finger, a middle finger, a ring finger and a little finger are in matched contact with edges of the two independent bottle bodies on the opposite side of the independent bottle bodies, so that the multi-cavity eyedrop bottle is taken up and moved to the upper part of an eyeball, the bottle opening of the multi-cavity eyedrop bottle faces downwards and keeps a distance of 1-1.8 cm with the eyeball, and the thumb is simultaneously and forcibly squeezed with one or two or three of the index finger, the middle finger, the ring finger and the little finger, so that eyedrop in the independent bottle body contacted with the thumb is squeezed out and converged into one drop to be dropped onto the eyeball.
In some embodiments, when the multi-cavity eyedrop bottle needs two independent bottle bodies to drip eyedrop, the outer side walls of the two independent bottle bodies are pressed with force, so that the eyedrop in the two independent bottle bodies is extruded out and converged into one drop to be dripped onto eyeballs; the method for dropping the eyedrops by the multi-cavity eyedrop bottle is suitable for the multi-cavity eyedrop bottle with two or four independent bottle bodies, the method of using a multi-chamber eyedrop bottle having two independent bottles is not described in detail, and when a multi-chamber eyedrop bottle having four independent bottles, the thumb is contacted with the middle part of the outer side wall of one of the four independent bottle bodies, one or two or three of the index finger, the middle finger, the ring finger and the little finger are matched to be contacted with the middle part of the outer side wall of the independent bottle body at the opposite side of the independent bottle body, thereby taking up the multi-cavity eyedrop bottle and moving the multi-cavity eyedrop bottle above the eyeball, keeping the bottle mouth of the multi-cavity eyedrop bottle downward and keeping a distance of 1-1.8 cm with the eyeball, and forcibly squeezing the thumb and one or two or three of index finger, middle finger, ring finger and little finger at the same time, so that eyedrops in the two independent bottle bodies contacted by the fingers are extruded out and converged into one drop to be dripped on the eyeballs.
In some embodiments, the multi-chamber eyedrop bottle can be uniformly forced to squeeze the eye drops by a mechanical gripper operation that simulates a human finger.
The above description is only for the embodiments of the present invention, and it will be apparent to those skilled in the art that various changes and modifications may be made without departing from the inventive concept thereof, and these changes and modifications are within the scope of the present invention.
Claims (8)
1. The manufacturing method of the multi-cavity eyedrop bottle is characterized by comprising the following steps:
a. designing and manufacturing a mould with each independent bottle body of the multi-cavity eye drop bottle;
b. melting the medical plastic particles by an injection molding technology and injecting the melted medical plastic particles into a bottle blank;
c. respectively placing the bottle blanks in the mold of each independent bottle body to be blow molded into independent bottle bodies;
d. moving the formed independent bottle body to the air for natural cooling;
e. removing burrs on the independent bottle body to obtain a finished independent bottle body;
combining two or more independent bottle bodies into a multi-cavity eyedrop bottle with consistent and level bottle opening direction;
when the outer side wall of the multi-cavity eyedrop bottle is pressed forcibly at the same time, the eyedrops in each cavity can be extruded out at the same time and converged into one drop to be dripped onto eyeballs;
when the multi-cavity eyedrop bottle consists of two independent bottle bodies, each independent bottle body is provided with a plane with the same shape, the plane of one independent bottle body is provided with a boss, the plane of the other independent bottle body is provided with a groove matched with the boss, and the two independent bottle bodies are combined into the multi-cavity eyedrop bottle by clamping the bosses and the grooves on the two independent bottle bodies;
when the multi-cavity eyedrop bottle consists of three or more independent bottle bodies, each independent bottle body is provided with two intersecting planes with consistent shapes, wherein one plane is provided with a boss, the other plane is provided with a groove matched with the boss, and the bosses and the grooves between the independent bottle bodies are mutually clamped, so that the multi-cavity eyedrop bottle is combined;
and when the independent bottle bodies are connected together, the threads on the bottle neck are spliced into an external thread which is matched and connected with the internal thread of the bottle cap.
2. A method of manufacturing a multi-chamber eyedrop bottle according to claim 1, wherein the individual bottles are glued on their flat surfaces and then snapped together to form a multi-chamber eyedrop bottle.
3. Use of a multi-chamber bottle made according to the method of claim 1, wherein the self-contained bottle body is adapted to contain eye drops including antibiotics, antivirals, antiallergic substances, mydriatic substances, antiglaucoma-type eyes and dry eye-drops.
4. Use of a multi-chamber vial according to claim 3, wherein the individual vials contain antibiotic eye drops comprising tobramycin and one or both of ofloxacin, rifampin, chloramphenicol, lincomycin, neomycin, gentamicin.
5. Use of a multi-chamber eyedrop bottle according to claim 3, wherein the individual bottles are adapted to hold an antiviral eyedrop comprising ribavirin and one or both of acyclovir and ganciclovir.
6. Use of a multi-chamber eyedrop bottle according to claim 3, wherein the individual bottle bodies contain anti-allergic eyedrops comprising one or two or three of azelastine and fluorometholone, pranoprofen, diclofenac, dexamethasone, prednisolone, cromolyn sodium, cyclosporine A, emedastine.
7. Use of a multi-chamber eyedrop bottle according to claim 3, wherein the individual bottles are adapted to hold mydriatic eye drops comprising atropine and sodium hyaluronate or tropicamide and one or both of epinephrine and norepinephrine.
8. Use of a multi-chamber eyedrop bottle according to claim 3, wherein the individual bottles are adapted to hold anti-glaucoma eyedrops comprising timolol and one or both of travoprost, brinzolamide, sodium hyaluronate, or 50% glucose and sodium hyaluronate, or pilocarpine and one or both of brinzolamide, sodium hyaluronate.
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| CN201911414486.2A CN110934743B (en) | 2019-12-31 | 2019-12-31 | Method for manufacturing multi-cavity eyedrop bottle, application and using method |
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| CN201911414486.2A CN110934743B (en) | 2019-12-31 | 2019-12-31 | Method for manufacturing multi-cavity eyedrop bottle, application and using method |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012162459A1 (en) * | 2011-05-26 | 2012-11-29 | Pepose Jay | Device and method for administering eye medications |
| CN203524992U (en) * | 2013-10-18 | 2014-04-09 | 郭晓琪 | Novel eyedrop bottle |
| CN105796339A (en) * | 2016-05-06 | 2016-07-27 | 成都理工大学 | Eye drop bottle |
| CN205867104U (en) * | 2016-05-17 | 2017-01-11 | 山东博士伦福瑞达制药有限公司 | Eye drops bottle containing a plurality of independent bottles |
| CN106389002A (en) * | 2016-09-28 | 2017-02-15 | 尹振图 | Liquid dropping bottle nozzle and eye drop bottle |
| CN106726556A (en) * | 2015-11-25 | 2017-05-31 | 上海市格致中学 | A kind of convenient eyedrops bottle |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2523421Y (en) * | 2001-12-24 | 2002-12-04 | 李季 | Eyedrops bottles |
| JP4378966B2 (en) * | 2003-02-07 | 2009-12-09 | 味の素株式会社 | Multi-chamber drug container |
| WO2013043607A1 (en) * | 2011-09-19 | 2013-03-28 | Kraft Daniel L | Eye drop dispenser |
| CN204246497U (en) * | 2014-11-15 | 2015-04-08 | 潍坊医学院附属医院 | A kind of quantitatively eyedrops bottle |
| CN107499700A (en) * | 2017-06-17 | 2017-12-22 | 福建奥正投资发展有限公司 | The sealing-plug valve member formula container closing appliance of the outer operation of lid, packing container and its application |
| CN107521861A (en) * | 2017-07-03 | 2017-12-29 | 福建奥正投资发展有限公司 | The gel spray nozzle type container closing appliance of the outer operation of lid, packing container and its application |
-
2019
- 2019-12-31 CN CN201911414486.2A patent/CN110934743B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012162459A1 (en) * | 2011-05-26 | 2012-11-29 | Pepose Jay | Device and method for administering eye medications |
| CN203524992U (en) * | 2013-10-18 | 2014-04-09 | 郭晓琪 | Novel eyedrop bottle |
| CN106726556A (en) * | 2015-11-25 | 2017-05-31 | 上海市格致中学 | A kind of convenient eyedrops bottle |
| CN105796339A (en) * | 2016-05-06 | 2016-07-27 | 成都理工大学 | Eye drop bottle |
| CN205867104U (en) * | 2016-05-17 | 2017-01-11 | 山东博士伦福瑞达制药有限公司 | Eye drops bottle containing a plurality of independent bottles |
| CN106389002A (en) * | 2016-09-28 | 2017-02-15 | 尹振图 | Liquid dropping bottle nozzle and eye drop bottle |
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| CN110934743A (en) | 2020-03-31 |
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