CN110922695A - Cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and preparation method thereof - Google Patents
Cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and preparation method thereof Download PDFInfo
- Publication number
- CN110922695A CN110922695A CN201911237891.1A CN201911237891A CN110922695A CN 110922695 A CN110922695 A CN 110922695A CN 201911237891 A CN201911237891 A CN 201911237891A CN 110922695 A CN110922695 A CN 110922695A
- Authority
- CN
- China
- Prior art keywords
- pvc
- sheet
- cobalt
- antioxidant
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/18—Manufacture of films or sheets
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2327/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers
- C08J2327/02—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers not modified by chemical after-treatment
- C08J2327/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08J2327/06—Homopolymers or copolymers of vinyl chloride
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/34—Silicon-containing compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/07—Aldehydes; Ketones
- C08K5/08—Quinones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/13—Phenols; Phenolates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/36—Sulfur-, selenium-, or tellurium-containing compounds
- C08K5/41—Compounds containing sulfur bound to oxygen
- C08K5/42—Sulfonic acids; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Materials Engineering (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention discloses a cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and a preparation method thereof, and particularly relates to the field of PVC products, wherein the used main materials comprise the following raw materials in parts by weight: 100-120 parts of PVC resin and 8-15 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224640-50% of antioxidant, 26420-30% of antioxidant, 10-15% of mica powder and 15-20% of anthraquinone coloring auxiliary agent. According to the invention, the PVC resin is modified by the composite antioxidant and the anthraquinone coloring auxiliary agent to prepare the transparent hard PVC sheet, so that the indexes of optimal product, high yield, low energy consumption and the like are achieved, the problems of atomization, pollution, color difference change and low light transmittance of the existing PVC sheet in the radiation dose of cobalt 60 and 30 can be solved, the mechanical strength of the PVC sheet is enhanced, the normal practicability of the PVC sheet is ensured, and the prepared medical package can be sterilized by cobalt 60 irradiation.
Description
Technical Field
The invention relates to the technical field of PVC products, in particular to a medical packaging sheet material of PVC with cobalt 60 irradiation resistance and disinfection and a preparation method thereof.
Background
With the development of the Chinese medicine market, the medical package is more and more emphasized by the industry and gradually becomes an important factor of market competition. The most common medical packaging materials at present are PVC (polyvinyl chloride), PVDC (polyvinylidene chloride) composite materials and vacuum aluminized materials. The multilayer composite hard sheet prepared by compounding or coating PVDC and other film materials, such as PVC/PVDC, BOPP/PVDC, PVC/PVDC/PE, PVDC/OPP/PE and the like, has the advantages of obviously higher oxygen permeability, moisture resistance and barrier property than the film of a single material, and integrates the advantages of various materials. A vacuum aluminized film is a packaging film in which aluminum is sprayed onto various base films in a high vacuum state. The materials widely used in the packaging of powders, granules and powders of Chinese patent drugs are PETP, CPP, FT, OPP, PE and other vacuum aluminized films, wherein the PETP, CPP and PE are the most widely applied. The vacuum aluminized film package has the characteristics of a plastic base film, beautiful decoration and good barrier property. Particularly, after various plastic base materials are aluminized, the light transmittance, the oxygen permeability, the water permeability and the water vapor permeability of the plastic base materials can be reduced to one dozen or even one hundredth. Can well prevent the drugs from mildewing and absorbing moisture. However, both PVDC (polyvinylidene chloride) composite materials and vacuum aluminized materials have a defect that cannot be solved at present, namely, the materials cannot be recycled, and the recycled materials are difficult to treat, so that potential safety hazards are generated to the environment. PVC is easy to form and seal, has low price, basically meets the requirements of medical packaging on transparency, barrier property and mechanical strength, and particularly can be recycled, so the PVC is the key point of the development of the existing medical packaging materials.
Currently, an important trend in the pharmaceutical packaging market is: ensures the stability of the medical material or the medicine in the storage period and the safety in use. Because medical packaging materials are sterilized before packaging medical devices or medicines, bacteria on the packaging materials are eliminated, the packaging devices or the medicines are not polluted, the traditional mode is cyclohexane sterilization, however, the mode has the problem of chemical agent residue and is gradually eliminated, and the currently considered safe sterilization mode is cobalt 60 irradiation sterilization, which brings great difficulty to PVC packaging materials. PVC is easy to dechlorinate and decompose when irradiated by cobalt 60 due to the problem of molecular structure, turns yellow, greatly reduces mechanical strength and loses service performance.
Disclosure of Invention
In order to overcome the defects in the prior art, the embodiment of the invention provides a medical packaging sheet material of PVC resistant to cobalt 60 irradiation sterilization and a preparation method thereof, and the technical problems to be solved by the invention are as follows: a PVC sheet was investigated which could ensure mechanical strength upon irradiation with cobalt 60.
In order to achieve the purpose, the invention provides the following technical scheme: the medical packaging sheet material of PVC with the function of resisting the disinfection of cobalt 60 irradiation comprises the following main materials in parts by weight: 100-120 parts of PVC resin and 8-15 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224640-50% of antioxidant, 26420-30% of antioxidant, 10-15% of mica powder and 15-20% of anthraquinone coloring auxiliary agent.
In a preferred embodiment, the anthraquinone coloring auxiliary agent is one of 1, 4-dihydroxyanthraquinone-2-sulfonate or 2.5.4 condensed ring anthraquinone.
In a preferred embodiment, the ratio between the total weight of the main material and the total weight of the auxiliary material is set to 100-.
In a preferred embodiment, the main materials used in the method comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224645 wt% of an antioxidant, 26425 wt% of an antioxidant, 12.5 wt% of mica powder, and 17.5 wt% of 1, 4-dihydroxy anthraquinone-2-sulfonate.
In a preferred embodiment, the main materials used in the method comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise 224645 wt% of antioxidant, 26425 wt% of antioxidant, 12.5 wt% of mica powder and 17.5 wt% of 2.5.4 fused ring anthraquinone in percentage by weight.
The invention also comprises a preparation method of the cobalt 60 irradiation resistant sterilized PVC medical packaging sheet, which comprises the following steps:
s1, mixing materials: preparing PVC resin, flame-retardant resin, mica powder and anthraquinone coloring auxiliary agent according to the proportion, adding the mixture into a mixing roll, carrying out low-speed mixing for 10-12min at the temperature of 130-140 ℃, and uniformly mixing to obtain a mixed material;
s2, a round of doping: adding an antioxidant 2246 into the mixed material obtained in the step S1, and increasing the mixing temperature of the mixing roll to 150-160 ℃ for low-speed mixing for 8-12min to obtain a round of mixed material;
s3, two rounds of doping: adding an antioxidant 264 into the first round of mixture obtained in the step S2, and increasing the mixing temperature of the mixing roll to 170-180 ℃ for low-speed mixing for 10-14min to obtain a second round of mixture;
s4, melt extrusion: conveying the two rounds of mixture obtained in the step S3 to a double-screw extruder for extrusion;
s5, cooling and shaping:
s5.1: performing calendaring on the sheet extruded in the step S4, and then performing spray cooling on a round of cooling water;
s5.2: the sheet was spray cooled to room temperature using two rounds of cooling water.
In a preferred embodiment, the temperature of the twin-screw extruder in the step S4 is set to 120-150 ℃, and the rotating speed is set to 30-50 r/min.
In a preferred embodiment, the temperature of the cooling water of one round is set to 30-45 ℃ and the temperature of the cooling water of two rounds is set to 12-15 ℃ in step S5.
The invention has the technical effects and advantages that:
1. according to the invention, the PVC resin is modified by the composite antioxidant and the anthraquinone coloring auxiliary agent to prepare the transparent hard PVC sheet, so that the indexes of optimal product, high yield, low energy consumption and the like are achieved, the problems of atomization, pollution, color difference change and low light transmittance of the existing PVC sheet in the radiation dose of cobalt 60 and 30 can be solved, the mechanical strength of the PVC sheet is enhanced, the normal practicability of the PVC sheet is ensured, and the prepared medical package can be sterilized by cobalt 60 irradiation;
2. the coloring auxiliary agent and the antioxidant of the invention are used for modifying PVC resin, and the obtained mechanism and data can provide reference data for products in other fields of PVC, and have important reference significance for the industry of PVC products in China.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
the invention provides a cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet, wherein the used main materials comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224645% of antioxidant, 37.5% of mica powder, and 17.5% of 1, 4-dihydroxy anthraquinone-2-sulfonate;
the proportion of the total weight of the main materials to the total weight of the auxiliary materials is set to be 100-115: 3-5.5.
The invention also comprises a preparation method of the cobalt 60 irradiation resistant sterilized PVC medical packaging sheet, which comprises the following steps:
s1, mixing materials: preparing PVC resin, flame-retardant resin, mica powder and anthraquinone coloring auxiliary agent according to the proportion, adding the mixture into a mixing roll, carrying out low-speed mixing for 10-12min at the temperature of 130-140 ℃, uniformly mixing to obtain a mixed material, adding the flame-retardant resin into the raw materials to modify the PVC sheet, greatly reducing the flammability of the PVC sheet, improving the mechanical property of the PVC sheet, adopting anthraquinone pigment as the coloring auxiliary agent of the PVC, and utilizing the action of the anthraquinone coloring auxiliary agent with reducibility to prevent hydrogen bonds and double bonds from being oxidized when cobalt 60 directly acts on the PVC sheet, thereby ensuring the structure of the PVC sheet and avoiding the problem of radiation discoloration of pigments such as traditional ultramarine blue;
s2, admixture: adding an antioxidant 2246 into the mixed material obtained in the step S1, and increasing the mixing temperature of the mixing roll to 150-160 ℃ for low-speed mixing for 8-12min to obtain a round of mixed material;
s3, melt extrusion: the two rounds of the mixture obtained in the step S3 are sent to a double-screw extruder for extrusion, the temperature is set to be 120-; the surface of the sheet semi-finished product with low extrusion speed is smooth, so that the extrusion quality of the tire tread is ensured;
s4, cooling and shaping:
s4.1: carrying out calendaring on the sheet extruded in the step S4, and then carrying out spray cooling on a round of cooling water, wherein the temperature of the cooling water in the round is set to be 30-45 ℃, and when the formed sheet leaves the extruder, the temperature of the sheet is up to more than 120 ℃, so that thermal deformation is easily generated, shrinkage and sizing of the sheet are accelerated, and the stability of specification and size is influenced; meanwhile, the sheet is easy to be burnt in the storage process, and the sheet is sprayed and cooled by using a round of cooling water;
s4.2: the sheet is sprayed and cooled to room temperature by two rounds of cooling water with the temperature of 12-15 ℃, the sheet is cooled to room temperature again by two rounds of low-temperature cooling water after the sheet is cooled for one round, and the sheet is stored after being cooled to room temperature again, and the sheet is gradually cooled in a segmented mode, so that the local shrinkage and frosting of the extruded sheet caused by quenching are avoided.
Example 2:
the invention provides a cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet, wherein the used main materials comprise the following raw materials in parts by weight: 100-120 parts of PVC resin and 8-15 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224640-50% of antioxidant, 26420-30% of antioxidant, 10-15% of mica powder and 15-20% of anthraquinone coloring auxiliary agent;
the anthraquinone coloring auxiliary agent is one of 1, 4-dihydroxy anthraquinones-2-sulfonate or 2.5.4 condensed ring anthraquinone;
the proportion of the total weight of the main materials to the total weight of the auxiliary materials is set to be 100: 115: 3-5.5;
specifically, in the embodiment, the used main materials comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224645 wt% of an antioxidant, 26425 wt% of an antioxidant, 12.5 wt% of mica powder, and 17.5 wt% of 1, 4-dihydroxy anthraquinone-2-sulfonate.
The invention also comprises a preparation method of the cobalt 60 irradiation resistant sterilized PVC medical packaging sheet, which comprises the following steps:
s1, mixing materials: preparing PVC resin, flame-retardant resin, mica powder and anthraquinone coloring auxiliary agent according to the proportion, adding the mixture into a mixing roll, carrying out low-speed mixing for 10-12min at the temperature of 130-140 ℃, uniformly mixing to obtain a mixed material, adding the flame-retardant resin into the raw materials to modify the PVC sheet, greatly reducing the flammability of the PVC sheet, improving the mechanical property of the PVC sheet, adopting anthraquinone pigment as the coloring auxiliary agent of the PVC, and utilizing the action of the anthraquinone coloring auxiliary agent with reducibility to prevent hydrogen bonds and double bonds from being oxidized when cobalt 60 directly acts on the PVC sheet, thereby ensuring the structure of the PVC sheet and avoiding the problem of radiation discoloration of pigments such as traditional ultramarine blue;
s2, a round of doping: adding an antioxidant 2246 into the mixed material obtained in the step S1, and increasing the mixing temperature of the mixing roll to 150-160 ℃ for low-speed mixing for 8-12min to obtain a round of mixed material;
s3, two rounds of doping: adding an antioxidant 264 into the one-round mixture obtained in the step S2, increasing the mixing temperature of a mixing roll to 170-180 ℃, carrying out low-speed mixing for 10-14min to obtain two-round mixtures, and preparing a composite antioxidant by adopting different antioxidant fractions to carry out oxidation-resistant modification on PVC resin, wherein when the PVC sheet prepared by the method is irradiated by cobalt 60, oxidation-resistant action can be continuously carried out in primary chain scission activity and secondary chain scission activity, so that the mechanical property of the PVC sheet is maintained;
s4, melt extrusion: the two rounds of the mixture obtained in the step S3 are sent to a double-screw extruder for extrusion, the temperature is set to be 120-; the surface of the sheet semi-finished product with low extrusion speed is smooth, so that the extrusion quality of the tire tread is ensured;
s5, cooling and shaping:
s5.1: carrying out calendaring on the sheet extruded in the step S4, and then carrying out spray cooling on a round of cooling water, wherein the temperature of the cooling water in the round is set to be 30-45 ℃, and when the formed sheet leaves the extruder, the temperature of the sheet is up to more than 120 ℃, so that thermal deformation is easily generated, shrinkage and sizing of the sheet are accelerated, and the stability of specification and size is influenced; meanwhile, the sheet is easy to be burnt in the storage process, and the sheet is sprayed and cooled by using a round of cooling water;
s5.2: the sheet is sprayed and cooled to room temperature by two rounds of cooling water with the temperature of 12-15 ℃, the sheet is cooled to room temperature again by two rounds of low-temperature cooling water after the sheet is cooled for one round, and the sheet is stored after being cooled to room temperature again, and the sheet is gradually cooled in a segmented mode, so that the local shrinkage and frosting of the extruded sheet caused by quenching are avoided.
Example 3:
the invention provides a cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet, wherein the used main materials comprise the following raw materials in parts by weight: 100-120 parts of PVC resin and 8-15 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224640-50% of antioxidant, 26420-30% of antioxidant, 10-15% of mica powder and 15-20% of anthraquinone coloring auxiliary agent;
the anthraquinone coloring auxiliary agent is one of 1, 4-dihydroxy anthraquinones-2-sulfonate or 2.5.4 condensed ring anthraquinone;
the proportion of the total weight of the main materials to the total weight of the auxiliary materials is set to be 100: 115: 3-5.5;
specifically, in the embodiment, the used main materials comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise 224645 wt% of antioxidant, 26425 wt% of antioxidant, 12.5 wt% of mica powder and 17.5 wt% of 2.5.4 fused ring anthraquinone in percentage by weight.
The invention also comprises a preparation method of the cobalt 60 irradiation resistant sterilized PVC medical packaging sheet, which comprises the following steps:
s1, mixing materials: preparing PVC resin, flame-retardant resin, mica powder and anthraquinone coloring auxiliary agent according to the proportion, adding the mixture into a mixing roll, carrying out low-speed mixing for 10-12min at the temperature of 130-140 ℃, uniformly mixing to obtain a mixed material, adding the flame-retardant resin into the raw materials to modify the PVC sheet, greatly reducing the flammability of the PVC sheet, improving the mechanical property of the PVC sheet, adopting anthraquinone pigment as the coloring auxiliary agent of the PVC, and utilizing the action of the anthraquinone coloring auxiliary agent with reducibility to prevent hydrogen bonds and double bonds from being oxidized when cobalt 60 directly acts on the PVC sheet, thereby ensuring the structure of the PVC sheet and avoiding the problem of radiation discoloration of pigments such as traditional ultramarine blue;
s2, a round of doping: adding an antioxidant 2246 into the mixed material obtained in the step S1, and increasing the mixing temperature of the mixing roll to 150-160 ℃ for low-speed mixing for 8-12min to obtain a round of mixed material;
s3, two rounds of doping: adding an antioxidant 264 into the one-round mixture obtained in the step S2, increasing the mixing temperature of a mixing roll to 170-180 ℃, carrying out low-speed mixing for 10-14min to obtain two-round mixtures, and preparing a composite antioxidant by adopting different antioxidant fractions to carry out oxidation-resistant modification on PVC resin, wherein when the PVC sheet prepared by the method is irradiated by cobalt 60, oxidation-resistant action can be continuously carried out in primary chain scission activity and secondary chain scission activity, so that the mechanical property of the PVC sheet is maintained;
s4, melt extrusion: the two rounds of the mixture obtained in the step S3 are sent to a double-screw extruder for extrusion, the temperature is set to be 120-; the surface of the sheet semi-finished product with low extrusion speed is smooth, so that the extrusion quality of the tire tread is ensured;
s5, cooling and shaping:
s5.1: carrying out calendaring on the sheet extruded in the step S4, and then carrying out spray cooling on a round of cooling water, wherein the temperature of the cooling water in the round is set to be 30-45 ℃, and when the formed sheet leaves the extruder, the temperature of the sheet is up to more than 120 ℃, so that thermal deformation is easily generated, shrinkage and sizing of the sheet are accelerated, and the stability of specification and size is influenced; meanwhile, the sheet is easy to be burnt in the storage process, and the sheet is sprayed and cooled by using a round of cooling water;
s5.2: the sheet is sprayed and cooled to room temperature by two rounds of cooling water with the temperature of 12-15 ℃, the sheet is cooled to room temperature again by two rounds of low-temperature cooling water after the sheet is cooled for one round, and the sheet is stored after being cooled to room temperature again, and the sheet is gradually cooled in a segmented mode, so that the local shrinkage and frosting of the extruded sheet caused by quenching are avoided.
Example 4:
the invention provides a cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet, wherein the used main materials comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise 26425 wt% of antioxidant, 57.5 wt% of mica powder and 17.5 wt% of 2.5.4 fused ring anthraquinone in percentage by weight;
the proportion of the total weight of the main materials to the total weight of the auxiliary materials is set to be 100-115: 3-5.5.
The invention also comprises a preparation method of the cobalt 60 irradiation resistant sterilized PVC medical packaging sheet, which comprises the following steps:
s1, mixing materials: preparing PVC resin, flame-retardant resin, mica powder and anthraquinone coloring auxiliary agent according to the proportion, adding the mixture into a mixing roll, carrying out low-speed mixing for 10-12min at the temperature of 130-140 ℃, uniformly mixing to obtain a mixed material, adding the flame-retardant resin into the raw materials to modify the PVC sheet, greatly reducing the flammability of the PVC sheet, improving the mechanical property of the PVC sheet, adopting anthraquinone pigment as the coloring auxiliary agent of the PVC, and utilizing the action of the anthraquinone coloring auxiliary agent with reducibility to prevent hydrogen bonds and double bonds from being oxidized when cobalt 60 directly acts on the PVC sheet, thereby ensuring the structure of the PVC sheet and avoiding the problem of radiation discoloration of pigments such as traditional ultramarine blue;
s2, admixture: adding an antioxidant 264 into the one-round mixture obtained in the step S2, increasing the mixing temperature of a mixing roll to 170-180 ℃, carrying out low-speed mixing for 10-14min to obtain two-round mixtures, and preparing a composite antioxidant by adopting different antioxidant fractions to carry out oxidation-resistant modification on PVC resin, wherein when the PVC sheet prepared by the method is irradiated by cobalt 60, oxidation-resistant action can be continuously carried out in primary chain scission activity and secondary chain scission activity, so that the mechanical property of the PVC sheet is maintained;
s3, melt extrusion: the two rounds of the mixture obtained in the step S3 are sent to a double-screw extruder for extrusion, the temperature is set to be 120-; the surface of the sheet semi-finished product with low extrusion speed is smooth, so that the extrusion quality of the tire tread is ensured;
s4, cooling and shaping:
s4.1: carrying out calendaring on the sheet extruded in the step S4, and then carrying out spray cooling on a round of cooling water, wherein the temperature of the cooling water in the round is set to be 30-45 ℃, and when the formed sheet leaves the extruder, the temperature of the sheet is up to more than 120 ℃, so that thermal deformation is easily generated, shrinkage and sizing of the sheet are accelerated, and the stability of specification and size is influenced; meanwhile, the sheet is easy to be burnt in the storage process, and the sheet is sprayed and cooled by using a round of cooling water;
s4.2: the sheet is sprayed and cooled to room temperature by two rounds of cooling water with the temperature of 12-15 ℃, the sheet is cooled to room temperature again by two rounds of low-temperature cooling water after the sheet is cooled for one round, and the sheet is stored after being cooled to room temperature again, and the sheet is gradually cooled in a segmented mode, so that the local shrinkage and frosting of the extruded sheet caused by quenching are avoided.
Example 5:
the PVC medical packaging sheets prepared in the above examples 1-4 were respectively tested, and the following data were obtained by testing the PVC medical packaging sheets prepared in the four examples in four components:
note: in the experiment process, the thickness of the sheet material is 0.5mm, and the test is carried out according to ASTM D1003 and GB/T22789.
From the above table, the PVC medical packaging sheets prepared in examples 2 and 3 have better parameter performance, wherein the light transmittance is greater than or equal to 88%, the haze is less than or equal to 2%, the cobalt is 60, the color difference value under 30 kgy radiation dose is less than or equal to 1.2, the tensile strength after sheet irradiation is greater than or equal to 45Mpa, and in addition, harmful substances such as ROHS, REACH-SVHC, and EN-71 are not detected in the detection process, so that the sheet meets the environmental protection standard, and can be applied to medical packaging.
And finally: the above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that are within the spirit and principle of the present invention are intended to be included in the scope of the present invention.
Claims (8)
1. The utility model provides a medical packaging sheet of PVC of resistant cobalt 60 irradiation disinfection which characterized in that: the used main materials comprise the following raw materials in parts by weight: 100-120 parts of PVC resin and 8-15 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224640-50% of antioxidant, 26420-30% of antioxidant, 10-15% of mica powder and 15-20% of anthraquinone coloring auxiliary agent.
2. The medical packaging sheet of PVC resistant to sterilization by cobalt 60 radiation as claimed in claim 1, wherein: the anthraquinone coloring auxiliary agent is one of 1, 4-dihydroxy anthraquinones-2-sulfonate or 2.5.4 condensed ring anthraquinone.
3. The medical packaging sheet of PVC resistant to sterilization by cobalt 60 radiation as claimed in claim 1, wherein: the proportion of the total weight of the main materials to the total weight of the auxiliary materials is set to be 100-115: 3-5.5.
4. The medical packaging sheet material of PVC resistant to sterilization by cobalt 60 radiation as claimed in claim 2, wherein: the used main materials comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise, by weight, 224645 wt% of an antioxidant, 26425 wt% of an antioxidant, 12.5 wt% of mica powder, and 17.5 wt% of 1, 4-dihydroxy anthraquinone-2-sulfonate.
5. The medical packaging sheet material of PVC resistant to sterilization by cobalt 60 radiation as claimed in claim 2, wherein: the used main materials comprise the following raw materials in parts by weight: 110 parts of PVC resin and 10 parts of flame-retardant resin, wherein the auxiliary materials comprise 224645 wt% of antioxidant, 26425 wt% of antioxidant, 12.5 wt% of mica powder and 17.5 wt% of 2.5.4 fused ring anthraquinone in percentage by weight.
6. The medical packaging sheet of PVC resistant to sterilization by cobalt 60 irradiation as claimed in any one of claims 1 to 5, wherein: the preparation method of the cobalt 60 irradiation resistant sterilized PVC medical packaging sheet comprises the following specific steps:
s1, mixing materials: preparing PVC resin, flame-retardant resin, mica powder and anthraquinone coloring auxiliary agent according to the proportion, adding the mixture into a mixing roll, carrying out low-speed mixing for 10-12min at the temperature of 130-140 ℃, and uniformly mixing to obtain a mixed material;
s2, a round of doping: adding an antioxidant 2246 into the mixed material obtained in the step S1, and increasing the mixing temperature of the mixing roll to 150-160 ℃ for low-speed mixing for 8-12min to obtain a round of mixed material;
s3, two rounds of doping: adding an antioxidant 264 into the first round of mixture obtained in the step S2, and increasing the mixing temperature of the mixing roll to 170-180 ℃ for low-speed mixing for 10-14min to obtain a second round of mixture;
s4, melt extrusion: conveying the two rounds of mixture obtained in the step S3 to a double-screw extruder for extrusion;
s5, cooling and shaping:
s5.1: performing calendaring on the sheet extruded in the step S4, and then performing spray cooling on a round of cooling water;
s5.2: the sheet was spray cooled to room temperature using two rounds of cooling water.
7. The preparation method of the PVC medical packaging sheet resistant to the disinfection of cobalt 60 irradiation as claimed in claim 6, wherein the preparation method comprises the following steps: the temperature of the twin-screw extruder in the step S4 is set to be 120-150 ℃, and the rotating speed range is set to be 30-50 r/min.
8. The preparation method of the PVC medical packaging sheet resistant to the disinfection of cobalt 60 irradiation as claimed in claim 6, wherein the preparation method comprises the following steps: the temperature of the cooling water of the first round is set to 30-45 ℃ and the temperature of the cooling water of the second round is set to 12-15 ℃ in the step S5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911237891.1A CN110922695A (en) | 2019-12-06 | 2019-12-06 | Cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911237891.1A CN110922695A (en) | 2019-12-06 | 2019-12-06 | Cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110922695A true CN110922695A (en) | 2020-03-27 |
Family
ID=69857907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911237891.1A Pending CN110922695A (en) | 2019-12-06 | 2019-12-06 | Cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110922695A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1443801A (en) * | 2002-03-12 | 2003-09-24 | 中国石化北京燕化石油化工股份有限公司树脂应用研究所 | Transparent polypropylene composition |
| CN102863720A (en) * | 2012-10-29 | 2013-01-09 | 成都市新津事丰医疗器械有限公司 | Medical polyvinyl chloride (PVC) material sterilized by gamma ray radiation |
| CN106751158A (en) * | 2016-12-01 | 2017-05-31 | 北京化工大学 | A kind of material of resistance to irradiated polymer and its production and use |
-
2019
- 2019-12-06 CN CN201911237891.1A patent/CN110922695A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1443801A (en) * | 2002-03-12 | 2003-09-24 | 中国石化北京燕化石油化工股份有限公司树脂应用研究所 | Transparent polypropylene composition |
| CN102863720A (en) * | 2012-10-29 | 2013-01-09 | 成都市新津事丰医疗器械有限公司 | Medical polyvinyl chloride (PVC) material sterilized by gamma ray radiation |
| CN106751158A (en) * | 2016-12-01 | 2017-05-31 | 北京化工大学 | A kind of material of resistance to irradiated polymer and its production and use |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108608707B (en) | Polyolefin crosslinked heat shrinkable film with shading effect and production process thereof | |
| CN108314818B (en) | Extinction casting PE film and preparation method thereof | |
| US20030068511A1 (en) | Transparent, multilayer, biaxially oriented polyester film, and process for its production | |
| CN102873954A (en) | Polyester film capable of being subjected to heat seal directly and preparation method | |
| JP2009509806A (en) | Plastic film | |
| CN108582904B (en) | Anti-ultraviolet barrier film and preparation method thereof | |
| CN111703165A (en) | Coating type multilayer composite high-barrier film, preparation method and application thereof | |
| JP2003526711A (en) | Thermoformable UV-resistant transparent film made of crystalline thermoplastic resin, its use and method for producing the same | |
| WO2024037440A1 (en) | Anti-sticking master batch for bope film, preparation method therefor, and use thereof | |
| CN103738015B (en) | A kind of transverse-thermal-sbidirectional bidirectional stretching polyester thin film and preparation method thereof | |
| CN110922695A (en) | Cobalt 60 irradiation-resistant sterilized PVC medical packaging sheet and preparation method thereof | |
| CN104212057A (en) | Flatting masterbatch for film | |
| CN111002677B (en) | Colored matte flame-retardant polyester film and preparation method thereof | |
| CN108530733A (en) | A kind of anti-aging type polyethylene color master batch and preparation method thereof | |
| CN107498965B (en) | A kind of super-thin low-voltage thermoplastic film and its preparation process | |
| CN108912487A (en) | A kind of PP feed back composite material and preparation method thereof of the low smell of automobile | |
| CN114044982B (en) | High-performance polypropylene extinction master batch and extinction film | |
| CN106751598A (en) | PC/PAR composites and preparation method thereof | |
| JP2003535734A (en) | Biaxially stretched coextruded white polyester film containing cycloolefin copolymer and having sealability, method for producing the same and use thereof | |
| JP2003520883A (en) | Thermoplastically moldable and UV-resistant white film made of crystalline thermoplastic resin, its use, and method of manufacturing the same | |
| CN115926300A (en) | Puncture-resistant tear-resistant PE (polyethylene) winding film and preparation method thereof | |
| WO2001053396A1 (en) | White flame-proofed thermoformable oriented film made from a crystallisable thermoplastic, a method for production and the use thereof | |
| CN113248821A (en) | Special material and film for high-coverage colored ETFE film particles, preparation method and application | |
| CN111995834A (en) | Modified particle based on PVA/starch and preparation method thereof | |
| CN110746753B (en) | PET film blowing bag and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200327 |
|
| RJ01 | Rejection of invention patent application after publication |