CN110873802A - Sample analyzer and automatic cleaning liquid path - Google Patents

Sample analyzer and automatic cleaning liquid path Download PDF

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Publication number
CN110873802A
CN110873802A CN201811012919.7A CN201811012919A CN110873802A CN 110873802 A CN110873802 A CN 110873802A CN 201811012919 A CN201811012919 A CN 201811012919A CN 110873802 A CN110873802 A CN 110873802A
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China
Prior art keywords
unit
valve
cleaning
communicated
interface
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Pending
Application number
CN201811012919.7A
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Chinese (zh)
Inventor
刘希昌
许焕樟
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Shenzhen Dymind Biotechnology Co Ltd
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Shenzhen Dymind Biotechnology Co Ltd
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Priority to CN201811012919.7A priority Critical patent/CN110873802A/en
Publication of CN110873802A publication Critical patent/CN110873802A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/02Cleaning by the force of jets or sprays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00475Filters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00564Handling or washing solid phase elements, e.g. beads

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The application discloses an automatic cleaning liquid path, which comprises a filtering unit, an injection unit and a cleaning liquid storage unit, wherein the filtering unit comprises a shell and a filter screen arranged in the shell; the injection unit is used for sucking the cleaning liquid from the cleaning liquid storage unit and injecting the cleaning liquid into the filtering unit so as to wash and clean the filter screen. The application also discloses a sample analyzer. Through the mode, waste residues accumulated on the filter screen can be automatically cleaned, and the filter unit is prevented from being blocked.

Description

Sample analyzer and automatic cleaning liquid path
Technical Field
The invention relates to the technical field of medical equipment, in particular to a sample analyzer and an automatic cleaning liquid path.
Background
At present, most of automatic sampling instruments adopt the following sample suction modes: the sampling needle descends to penetrate through the test tube cap to suck a sample in the test tube, then the sampling needle ascends to add the sample into the reaction tank. When the sampling needle passes through the test tube cap, the interaction of the needle and the test tube cap can cause the outer wall of the needle to be stained with chips, and further the performance of the instrument is influenced. The existing common solution is that the outer wall of the needle is cleaned by a swab in the ascending process of the needle, and in order to prevent the cleaned debris from affecting components such as a valve pump, a filter is arranged at the front end of the component of the valve pump and used for collecting the debris cleaned by the swab. However, in a physical examination center with a large sample amount every day, the amount of debris in the filter is increased quickly, and if the filter is not replaced in time, the risks that the outer wall of the sampling needle is not cleaned completely and the swab leaks are increased, so that the performance of the instrument is poor. In addition, the filter needs to be replaced by a professional, and the frequent replacement of the filter undoubtedly results in the operation cost of the company and influences the experience of the user.
Disclosure of Invention
The invention mainly solves the technical problem of providing a sample analyzer and an automatic cleaning liquid path, which can automatically clean waste residues accumulated on a filter screen and avoid the blockage of a filter unit.
In order to solve the above technical problem, one technical solution adopted in the embodiments of the present application is: the automatic cleaning liquid path comprises a filtering unit, an injection unit and a cleaning liquid storage unit, wherein the filtering unit comprises a shell and a filter screen arranged in the shell; the injection unit is used for sucking the cleaning liquid from the cleaning liquid storage unit and injecting the cleaning liquid into the filtering unit so as to wash and clean the filter screen.
In order to solve the above technical problem, another technical solution adopted in the embodiment of the present application is: a sample analyzer is provided that includes the automatic cleaning fluid circuit described above.
The automatic cleaning liquid path comprises a filtering unit, an injection unit and a cleaning liquid storage unit, wherein the filtering unit comprises a shell and a filter screen arranged in the shell; the injection unit is used for absorbing the cleaning fluid from the cleaning fluid storage unit and injecting the cleaning fluid into the filter unit so as to wash and clean the filter screen, and can automatically clean the waste residues accumulated on the filter screen to avoid the blockage of the filter unit.
Drawings
FIG. 1 is a schematic diagram of a liquid path structure of an automatic cleaning liquid path according to an embodiment of the present disclosure;
FIG. 2 is a schematic structural diagram of a filter unit according to an embodiment of the present application;
FIG. 3 is a schematic diagram illustrating an electrical connection of an automatic cleaning liquid path according to an embodiment of the present disclosure.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
The terms "first", "second", etc. in this application are used to distinguish between different objects and not to describe a particular order. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
Referring to fig. 1 and 2, fig. 1 is a schematic view of a liquid path structure of an automatic cleaning liquid path according to an embodiment of the present application; fig. 2 is a schematic structural diagram of a filter unit according to an embodiment of the present application.
In the present embodiment, the automatic cleaning solution path includes a filtering unit 10, an injection unit 20, a cleaning solution storage unit 30, a cleaning unit 40, an extraction unit 50, a waste solution storage unit 60, a sensing unit 70, a first valve LV1, a second valve LV2, a third valve LV3, a fourth valve LV4, a first three-way joint 80, a second three-way joint 90, and a third three-way joint 100.
The filter unit 10 includes a housing 11 and a filter screen 12 disposed in the housing 11.
The injection unit 20 is used for sucking the cleaning liquid from the cleaning liquid storage unit 30 and injecting the cleaning liquid into the filter unit 10 to wash and clean the filter screen 12.
Optionally, the filter screen 12 divides the accommodating space formed by the housing into a first subspace 111 and a second subspace 112 located below the first subspace 111.
Optionally, the filter unit 10 further comprises a cleaning interface 13, the cleaning interface 13 being in communication with the second subspace 111, cleaning fluid from the injection unit 20 entering from the cleaning interface 13.
Optionally, the injection unit 20 is also used to suck the washing liquid from the washing liquid storage unit 30 and inject the washing liquid into the washing unit 40 to wash the outer wall of the sample needle 401. When the washing unit 40 is covered by a swab 402 on the sample needle 401, the swab 402 and the outer wall of the sample needle 401 form a washing space. Alternatively, the swab 402 may be controlled to move along the length of the sample needle 401 relative to the sample needle 401 to wash different positions along the length of the sample needle 401.
Optionally, the filtering unit 10 further comprises a waste receiving interface 14 and a waste discharging interface 15, which are communicated with the first subspace 111, the waste receiving interface 14 is used for receiving waste discharged from the cleaning unit 40, the waste discharging interface 15 is used for discharging waste in the waste, and the cleaning interface 13 is also used for discharging the waste.
Alternatively, the sensing unit 70 is used to detect a line pressure between the filter unit 10 and the cleaning unit 40, and control the injection unit 20 to suck the cleaning solution from the cleaning solution storage unit 30 and inject the cleaning solution into the filter unit 10 when the pressure is greater than a predetermined value, so as to perform the flushing cleaning of the filter mesh 12.
Alternatively, the injection unit 20 is controlled to suck the washing liquid from the washing liquid storage unit 30 and inject the washing liquid into the washing unit 40 when the pressure is less than a predetermined value to wash the outer wall of the sample needle 401.
Optionally, the filter 12 is disposed in the housing 11 in an inclined manner and is inclined gradually downwards in the direction from the waste liquid receiving port 14 to the waste residue discharge port 15. So that the slag can be easily discharged from the slag discharge port 15.
Optionally, the waste receiving interface 14 has an inner diameter that is smaller than the inner diameter of the waste discharge interface 15.
The functions of the above units can be realized by the following liquid path connection relationship, but is not limited to the realization of the following liquid path elements and liquid path connection relationship, and other liquid paths that can be designed by those skilled in the art according to the above description are all within the protection scope of the present application.
The first end of the first valve LV1 is communicated with the injection port of the injection unit, the second end of the first valve LV1 is communicated with the liquid inlet port 41 of the cleaning unit 40, and the third end of the first valve LV1 is communicated with the first end of the second valve LV 2.
A second end of the second valve LV2 is communicated with a second end of the first three-way joint 80, and a third end of the second valve LV2 is communicated with the cleaning liquid storage unit 30;
the liquid outlet port 42 of the cleaning unit 40 is communicated with a first end of the second three-way joint 90;
the first end of the third valve LV3 is connected to the second end of the second three-way joint 90, and the second end of the third valve LV3 is connected to the waste liquid receiving port 14 of the filtering unit 10.
The detection interface 71 of the sensing unit 70 is communicated with the third end of the second three-way joint 90.
The cleaning port 13 of the filter unit 10 communicates with a first end of the first three-way joint 80, and the waste residue discharge port 15 of the filter unit 10 communicates with a first end of the fourth valve LV 4.
A second end of the fourth valve LV4 is communicated with a third end of the third three-way joint 100;
the first end of the extraction unit 50 is communicated with the third end of the first three-way joint 80, and the second end of the extraction unit 50 is communicated with the first end of the third three-way joint 100.
The second end of the third three-way joint 100 communicates with the waste liquid storage unit 60.
Wherein, the first end of the first valve LV1 is selectively communicated with the second end or the third end thereof; the first end of the second valve LV2 is selectively communicated with the second end or the third end thereof; the first end of the third valve LV3 is selectively connected or disconnected with the second end thereof; the first end of the fourth valve LV4 is selectively connected to or disconnected from the second end thereof, and the pumping unit 50 is used for generating negative pressure to pump the liquid from the first end thereof to the second end thereof. The extraction unit 50 may be an extraction pump.
Three ends of each of the first three-way joint 80, the second three-way joint 90, and the third three-way joint 100 communicate with each other.
Optionally, the first valve LV1 and the second valve LV2 are two-position three-way solenoid valves.
Optionally, the third valve LV3 and the fourth valve LV4 are both pressure-break solenoid valves that are not easily blocked.
It will be understood by those skilled in the art that the above "communication" means connection by piping.
Referring to fig. 3, fig. 3 is a schematic diagram illustrating an electrical connection principle of an automatic cleaning liquid path according to an embodiment of the present application.
The automatic cleaning liquid path may further include an injection driving mechanism 31, a control unit 32, and a sampling needle driving mechanism 33, and the control unit 32 may be implemented by a processor and its peripheral circuits.
The control unit 32 is electrically connected with the injection unit driving mechanism 31, the sampling needle driving mechanism 33, the first valve LV1, the second valve LV2, the third valve LV3, the fourth valve LV4 and the sensing unit 70.
The injection unit driving mechanism 31 is used to drive the piston of the injection unit 20 to advance or retract, and to control the stroke of the piston of the injection unit 20 to advance or retract.
The sampling needle driving mechanism 33 is used to drive the up-and-down movement of the sampling needle 401.
The control principle is explained below.
Low debris (i.e., slag): when the sensing unit 70 detects that the pressure of the pipeline b is less than the preset value, which indicates that there is less debris in the filtering unit 10, the control unit 32 generates a command for cleaning the sampling needle 401, the control unit 32 controls the sampling needle driving mechanism 33 to drive the sampling needle 401 to move upwards, controls the extraction unit 50 to start working, and controls the first end of the first valve LV1 to communicate with the third end thereof, the first end of the second valve LV2 to communicate with the third end thereof, controls the injection unit 20 to suck the cleaning liquid from the cleaning liquid storage unit 30, then controls the first end of the first valve LV1 to communicate with the second end thereof, and pushes the cleaning liquid into the cleaning unit 40 through the pipeline a, the extraction unit 50 provides a suction force to extract the waste liquid in the cleaning unit 40, the waste liquid enters the waste liquid storage unit 60 through the pipeline b, the filtering unit 10, the pipelines e and d, thereby cleaning the sampling needle 401, and the debris and other impurities are filtered by the filter screen, and the filter screen is left above the filter screen.
The situation of much debris: when the sensing unit 70 detects that the pressure of the pipeline b is greater than the preset value, which indicates that there are more debris in the filtering unit 10, the control unit 32 generates an instruction for cleaning the filtering net 12, and when there are more debris in the filtering unit 10, the suction force of the suction unit 50 to the pipeline b is affected because there are more debris above the filtering net 12, and in this case, when the sampling needle 401 is cleaned, the negative pressure in the pipeline b is greater than the preset safety pressure, and then the cleaning of the filtering unit 10 is performed.
Automatic cleaning process of the filter unit 10: the control unit 32 controls the first end of the first valve LV1 to communicate with the third end thereof, controls the first end of the second valve LV2 to communicate with the third end thereof, controls the injection unit 20 to suck the cleaning solution from the cleaning solution storage unit 30 to communicate with the pipes g and h, controls the third valve LV3 to be closed (the first end thereof is blocked from the second end thereof), closes the pipe b, and controls the fourth valve LV4 to be opened to communicate with the pipe c; the piston movement of the injection unit 20 is controlled to push the cleaning liquid into the filter unit 10 from the cleaning port 13 of the filter unit 50 through the pipes g, f, and when the liquid reaches a certain amount in the filter unit 10 by means of the pushing force of the injection unit 20, the liquid with a large amount of debris flows out of the waste residue discharge port 15 of the filter unit 50 and is discharged into the waste liquid storage unit 60 through the pipes c, d.
The pipes c and d, i.e., the pipes from the waste residue discharge port 15 to the waste liquid storage unit 60, are selected to have a larger inner diameter than the pipes of the other pipes (e.g., the pipes a, b, e, f, g, h) so as to prevent the waste residue from clogging the pipes c and d. And the pipes c, d may be disposed obliquely or in a vertical direction when actually placed, so that the liquid with a large amount of debris can be discharged into the waste liquid storage unit 60 by its own weight.
The sample analyzer of the present application may include the automatic cleaning fluid path of any of the embodiments described above.
According to the embodiment of the application, the automatic cleaning liquid path comprises a filtering unit, an injection unit and a cleaning liquid storage unit, wherein the filtering unit comprises a shell and a filter screen arranged in the shell; the injection unit is used for absorbing the cleaning fluid from the cleaning fluid storage unit and injecting the cleaning fluid into the filter unit so as to wash and clean the filter screen, and can automatically clean the waste residues accumulated on the filter screen to avoid the blockage of the filter unit.
The above description is only for the purpose of illustrating embodiments of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings of the present application or are directly or indirectly applied to other related technical fields, are also included in the scope of the present application.

Claims (10)

1. An automatic cleaning liquid path is characterized by comprising a filtering unit, an injection unit and a cleaning liquid storage unit,
the filtering unit comprises a shell and a filtering net arranged in the shell;
the injection unit is used for sucking the cleaning liquid from the cleaning liquid storage unit and injecting the cleaning liquid into the filtering unit so as to wash and clean the filter screen.
2. The automatic cleaning solution path of claim 1, wherein the filter screen divides the receiving space formed by the housing into a first subspace and a second subspace located below the first subspace, the filter unit further comprising a cleaning interface, the cleaning interface being in communication with the second subspace, the cleaning solution from the injection unit entering through the cleaning interface.
3. The automatic cleaning solution path of claim 2, further comprising a cleaning unit, wherein the injection unit is further configured to draw a cleaning solution from the cleaning solution storage unit and inject the cleaning solution into the cleaning unit to clean an outer wall of a sample needle, wherein the filtering unit further comprises a waste liquid receiving interface and a waste residue discharging interface, the waste liquid receiving interface is configured to receive waste liquid discharged from the cleaning unit, the waste residue discharging interface is configured to discharge waste residues in the waste liquid, and the cleaning interface is further configured to discharge the waste liquid.
4. The automatic cleaning solution path of claim 3, further comprising a sensing unit for detecting a line pressure between the filtering unit and the cleaning unit, and controlling the injection unit to suck the cleaning solution from the cleaning solution storage unit and inject the cleaning solution into the filtering unit when the pressure is greater than a predetermined value, so as to wash and clean the filter screen.
5. The automatic cleaning liquid path of claim 4, wherein the injection unit is controlled to suck the cleaning liquid from the cleaning liquid storage unit and inject the cleaning liquid into the cleaning unit when the pressure is less than a predetermined value to clean the outer wall of the sample needle.
6. The automatic cleaning solution path of claim 3, wherein the filter screen is disposed in the housing in an inclined manner and is inclined gradually downward in a direction from the waste liquid receiving port to the waste residue discharging port.
7. The automatic cleaning solution path of claim 3, wherein an inner diameter of the waste liquid receiving port is smaller than an inner diameter of the waste residue discharging port.
8. The automatic cleaning fluid circuit of claim 5, further comprising: the device comprises an extraction unit, a waste liquid storage unit, a first valve, a second valve, a third valve, a fourth valve, a first three-way joint, a second three-way joint and a third three-way joint;
the first end of the first valve is communicated with an injection interface of the injection unit, the second end of the first valve is communicated with a liquid inlet interface of the cleaning unit, and the third end of the first valve is communicated with the first end of the second valve;
the second end of the second valve is communicated with the second end of the first three-way joint, and the third end of the second valve is communicated with the cleaning liquid storage unit;
the liquid outlet interface of the cleaning unit is communicated with the first end of the second three-way joint;
the first end of the third valve is communicated with the second end of the second three-way joint, and the second end of the third valve is communicated with the waste liquid receiving interface of the filtering unit;
the detection interface of the sensing unit is communicated with the third end of the second three-way joint;
a cleaning interface of the filtering unit is communicated with a first end of the first three-way joint, and a waste residue discharging interface of the filtering unit is communicated with a first end of the fourth valve;
the second end of the fourth valve is communicated with the third end of the third tee joint;
the first end of the extraction unit is communicated with the third end of the first tee joint, and the second end of the extraction unit is communicated with the first end of the third tee joint;
the second end of the third tee joint is communicated with the waste liquid storage unit;
wherein the first end of the first valve is selectively communicated with the second end or the third end of the first valve; the first end of the second valve is selectively communicated with the second end or the third end of the second valve; the first end and the second end of the third valve are selectively communicated or cut off; the first end of the fourth valve is selectively communicated with or cut off from the second end of the fourth valve, and the extraction unit is used for generating negative pressure to extract liquid from the first end of the extraction unit to the second end of the extraction unit.
9. The automatic cleaning solution circuit of claim 8, wherein the third valve and the fourth valve are pressure break valves.
10. A sample analyzer, comprising the self-cleaning fluid circuit of any one of claims 1-9.
CN201811012919.7A 2018-08-31 2018-08-31 Sample analyzer and automatic cleaning liquid path Pending CN110873802A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811012919.7A CN110873802A (en) 2018-08-31 2018-08-31 Sample analyzer and automatic cleaning liquid path

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811012919.7A CN110873802A (en) 2018-08-31 2018-08-31 Sample analyzer and automatic cleaning liquid path

Publications (1)

Publication Number Publication Date
CN110873802A true CN110873802A (en) 2020-03-10

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CN201811012919.7A Pending CN110873802A (en) 2018-08-31 2018-08-31 Sample analyzer and automatic cleaning liquid path

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113695322A (en) * 2021-08-31 2021-11-26 中元汇吉生物技术股份有限公司 Sampling needle cleaning device and cleaning method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113695322A (en) * 2021-08-31 2021-11-26 中元汇吉生物技术股份有限公司 Sampling needle cleaning device and cleaning method thereof

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