CN110861330A - Process method and manufacturing equipment for liquid packaging product - Google Patents
Process method and manufacturing equipment for liquid packaging product Download PDFInfo
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- CN110861330A CN110861330A CN201911134570.9A CN201911134570A CN110861330A CN 110861330 A CN110861330 A CN 110861330A CN 201911134570 A CN201911134570 A CN 201911134570A CN 110861330 A CN110861330 A CN 110861330A
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- liquid
- sterile
- embedding
- insert
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D22/00—Producing hollow articles
- B29D22/003—Containers for packaging, storing or transporting, e.g. bottles, jars, cans, barrels, tanks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
- B65B61/18—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for making package-opening or unpacking elements
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Basic Packing Technique (AREA)
- Containers And Plastic Fillers For Packaging (AREA)
Abstract
The invention discloses a process method of a liquid packaging product, which comprises the following steps: extruding a tube blank for forming a liquid package and into an open mold comprising a main mold and a head mold, closing the main mold to form the liquid package; filling liquid with preset dosage into the liquid packaging product; inserting a predetermined sterile insert into a predetermined location of the liquid package; closing the head die and sealing the liquid packaging product. Directly embedding the preset sterile insert into the liquid packaging product in the process of forming the liquid packaging product, so that the preset sterile insert and the liquid packaging product form an integrally formed structure, the sterility in the production process is ensured, and the preset sterile insert and the liquid packaging product are matched for use so as to meet the sterile use requirement of the liquid packaging product; and also avoids contamination of the fluid during implantation of the pre-sterile insert at a later time of use. The invention also discloses a manufacturing device of the liquid packaging product for realizing the process method of the liquid packaging product.
Description
Technical Field
The invention relates to the technical field of pharmacy, in particular to a process method of a liquid package product. In addition, the invention also relates to a manufacturing device of the liquid packaging product for realizing the process method of the liquid packaging product.
Background
The BFS (blow Fill seal) technology is used as a blowing, filling and sealing three-in-one aseptic packaging technology, has wide application in the technical field of medicine, and integrates container forming, liquid filling and container sealing, namely, the blowing, filling and sealing integrated machine is adopted to complete the whole bottle-making, filling and sealing process of liquid packaging products in an aseptic state.
When the liquid packaging product after the sealing is used at the later stage, the sealing is only required to be opened, and the liquid in the liquid packaging product is directly taken or the functional element matched with the liquid packaging product is inserted from the opening for use.
However, in the use process, direct access to the liquid in the liquid package is mainly directed to single-dose or single-dose complete use of the liquid, while for multi-dose or multi-use liquids, after the first use, the liquid package is less sealed because the seal of the liquid package is opened, and the remaining liquid in the liquid package after a certain period of time is contaminated, for example, by increasing or even exceeding the content of harmful substances such as endotoxin and insoluble particles, which may threaten the life of a patient if the liquid is reused.
For the liquid packaging product which needs to be inserted with the matched functional element from the opening, because the seal of the liquid packaging product is opened, the external interference factor is large, and the liquid is inevitably polluted in the process of inserting the functional element, so that the sterility of the liquid or the functional element can not meet the requirement, and certain hidden trouble exists for the body health of a patient. Furthermore, the injection needle, the injection plug and the like implanted in the later period are directly used for intramuscular injection or culture of patients, so that liquid medicine pollution in the dispensing process is easily caused, and the dispensing risk is high.
In summary, the technical problem to be solved by those skilled in the art is how to provide a method for manufacturing a liquid package product to avoid the contamination of the liquid during the later use.
Disclosure of Invention
In view of the above, the present invention is directed to a method and an apparatus for manufacturing a liquid package, which can prevent the liquid package from being contaminated during the later use.
In order to achieve the above purpose, the invention provides the following technical scheme:
a process for the manufacture of a liquid package comprising:
extruding a tube blank for forming a liquid package and into an open mold comprising a main mold and a head mold, closing the main mold to form the liquid package;
filling a preset dosage of liquid into the liquid packaging product;
inserting a predetermined sterile insert into a predetermined location of said liquid package;
and closing the head die and sealing the liquid packaging product.
Preferably, the pre-sterile insert comprises a sterile rubber plug which can be used by multiple puncture seals, a flow restriction element or a needle for limiting the amount of liquid.
Preferably, before said inserting the predetermined sterile insert into the predetermined position of the liquid packaging article, further comprises:
and forming the preset position into an embedding hole matched with the preset sterile embedding piece.
An apparatus for manufacturing liquid packages, comprising:
an extruding device for extruding a tube blank for forming a liquid package;
a master mould for forming the liquid package when closed;
a filling device for filling a predetermined amount of liquid into the liquid package;
an inserting means for inserting a predetermined sterile insert into a predetermined position of said liquid pack;
a head die for sealing the liquid pack when closed;
and the control systems are respectively connected with the extrusion device, the filling device, the embedding device, the main die and the actuating mechanism of the head die so as to control the extrusion device, the filling device, the embedding device, the main die and the head die to coordinate and orderly move to complete the forming, filling, embedding and sealing of the container.
Preferably, the end of the filling tube of the filling device is provided with an insert molding die for molding the predetermined position into an insert hole adapted to the predetermined sterile insert.
Preferably, the preset sterile inserting piece is a sterile rubber plug, the insert molding die comprises a plugging portion corresponding to a plug head of the sterile rubber plug, and the main die is provided with an inserting neck die for guiding the plugging portion.
Preferably, the aseptic plug comprises a cap connected to the stopper head, and the head die is provided with a head die plug die for molding the liquid packaging product into a second molding surface having the same outer profile as that of the cap.
Preferably, the embedding device comprises:
the embedded suction pipe is used for sucking the preset sterile embedded part, and a vacuum channel is arranged inside the embedded suction pipe;
the first driving mechanism is connected with the embedding straw and is used for driving the embedding straw to move between the material taking position of the preset sterile embedding part and the embedding position of the preset sterile embedding part;
and the second driving mechanism is connected with the embedding straw and is used for driving the embedding straw to lift so as to realize material taking or embedding into the preset sterile embedding piece.
Preferably, the method further comprises the following steps:
an aseptic transfer drum for loading the pre-set aseptic inserts;
a closed shock disk connected to the sterile transfer cask through an αβ valve.
Preferably, the closed type vibration disc is provided with a sterile wind inlet pipeline for introducing sterile wind with stable flow and stable positive pressure into the closed type vibration disc, and the sterile wind inlet pipeline is provided with a sterilization grade filter and a precision pressure reducing valve.
The invention provides a process method of a liquid packaging product, which is characterized in that after a preset dosage of liquid is filled into the liquid packaging product, and before a head die is folded and the liquid packaging product is sealed, a preset sterile insert is inserted into a preset position of the liquid packaging product. Namely, the preset sterile insert is directly embedded into the liquid packaging product in the process of forming the liquid packaging product, so that the preset sterile insert and the liquid packaging product form an integrally formed structure, on one hand, the sterility of the production process is ensured, and on the other hand, the preset sterile insert is matched with the liquid packaging product for use so as to meet the sterile use requirement of the liquid packaging product; in addition, the preset sterile insert can be prevented from being implanted in the later-stage use process, so that the temporary assembly process of the preset sterile insert and the liquid packaging product in the later-stage use process is avoided, and further the liquid is prevented from being polluted in the later-stage temporary assembly process.
The manufacturing equipment of the liquid packaging product provided by the invention can realize the whole processes of container forming, filling, embedding and sealing of the liquid packaging product through the coordination and orderly cooperation of the extruding device, the filling device, the embedding device, the main die and the head die under the control of the control system. Compared with the blowing, filling and sealing integrated machine in the prior art, the manufacturing equipment of the liquid packaging product enables the preset sterile embedded part and the liquid packaging product to be in an integrated structure, and meets the sterile use requirement of the liquid packaging product by matching the preset sterile embedded part with the liquid packaging product; and also avoids the pollution to the liquid in the process of implanting the preset sterile insert in the process of later use.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a flow chart of a process for producing a liquid pack according to an embodiment of the present invention;
FIG. 2 is a schematic view showing a relative position of a partial structure of an apparatus for manufacturing liquid packages according to an embodiment of the present invention;
FIG. 3 is a top view of the sterile transfer cask and enclosed shaker tray of FIG. 2;
FIG. 4 is a cross-sectional view of the process of filling the liquid into the liquid package;
FIG. 5 is a cross-sectional view of a pre-sterile insert insertion process;
fig. 6 is a cross-sectional view of a pre-set sterile insert being inserted into a liquid package.
The reference numerals in fig. 1 to 6 are as follows:
the device comprises a main die 1, an embedding neck die 11, an embedding device 2, an embedding suction pipe 21, a guide rail 22, a sliding block 23, a head die 3, a head die rubber plug die 31, a filling pipe 4, an embedding forming die 41, an aseptic rubber plug 5, an aseptic transfer barrel 6, an αβ valve passive valve 61, a closed vibrating disk 7, a αβ valve driving valve 71, an aseptic air inlet pipeline 72, a sterilization grade filter 73, a precision pressure reducing valve 74 and a discharge pipe 75.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The core of the invention is to provide a process method and a manufacturing device of the liquid packaging product, which can avoid the liquid from being polluted in the later use process of the liquid packaging product.
Referring to fig. 1, a flow chart of a method for manufacturing a liquid packaging product according to an embodiment of the present invention is shown.
The invention provides a process method of a liquid packaging product, which comprises the following steps:
s1: extruding a tube blank for forming a liquid package and inserting the tube blank into an open mold comprising a main mold and a head mold, and closing the main mold to form the liquid package.
S2: a predetermined dose of liquid is filled into the liquid package.
S3: a predetermined sterile insert is inserted into a predetermined location of the liquid package.
S4: closing the head die and sealing the liquid packaging product.
First, the liquid packaging product in the present invention refers to an infusion bottle, an infusion bag, or the like containing a liquid.
Next, the steps of S1 to S4 are performed in the same sterile environment to ensure the sterility of the production process.
It can be seen that the operations of S1, S2, and S4 in the above steps are the same as the conventional operations of the BFS aseptic packaging process in the prior art, and will not be described in detail herein.
The present invention is focused on the further improvement of the prior art BFS aseptic packaging process, i.e. the insertion of a pre-sterile insert into the liquid package at a pre-set position after filling the liquid package with a pre-set dose of liquid and before closing the head die 3 and sealing the liquid package. Namely, the three-in-one BFS aseptic packaging process of bottle blowing, filling and sealing in the prior art is changed into the four-in-one BFIS (blow FillInsert seal) aseptic packaging process of bottle blowing, filling, embedding and sealing, and an embedding process step is added on the basis of the traditional aseptic process, so that the product is more widely used.
The invention has the general inventive concept that the preset sterile insert is directly embedded into the liquid packaging product in the process of forming the liquid packaging product, so that the preset sterile insert and the liquid packaging product form an integrated forming structure, on one hand, the sterility in the production process is ensured, and on the other hand, the preset sterile insert and the liquid packaging product are matched for use so as to meet the sterile use requirement of the liquid packaging product; in addition, the preset sterile insert can be prevented from being implanted in the later-stage use process, so that the temporary assembly process of the preset sterile insert and the liquid packaging product in the later-stage use process is avoided, and further the liquid is prevented from being polluted in the later-stage temporary assembly process.
The particular predetermined sterile insert to be inserted into the liquid package may be selected by those skilled in the art according to the actual requirements.
For example, for multi-dose or multi-use liquid packages, the predetermined sterile insert may be a sterile plug that can be used by multiple punctures, i.e., a sterile plug is inserted directly into the liquid package during the formation of the liquid package. During the later stage use, when opening the seal of liquid packaging article, after the liquid in the liquid packaging article is used for the first time, because the existence of aseptic plug, can ensure the leakproofness of liquid packaging article, the remaining liquid of avoiding after the first time use receives the pollution, ensures the security that the patient used medicine many times.
In addition, for liquid packages such as eye drops and the like, the preset sterile insert can also be a flow limiting element for limiting the liquid amount, namely, the liquid amount flowing out each time is limited by the flow limiting element, so that the uncertain liquid amount flowing out from the sealing opening caused by the uncertain size of the opening sealing opening is avoided.
Certainly, predetermine aseptic embedded part still can be the syringe needle, promptly, directly inlay in liquid packaging article and establish the syringe needle, when later stage uses, will seal the back, directly utilize the syringe needle in the liquid packaging article to operate can. On one hand, the needle head can be prevented from being polluted in the later implantation process, on the other hand, the liquid medicine can be prevented from being polluted in the dispensing process, and the dispensing risk is reduced.
Of course, the preset sterile insert can also be other functional elements, which are not illustrated here, and can be selected by the person skilled in the art according to the actual needs.
On the basis of the above embodiment, before inserting the pre-set sterile insert into the pre-set position of the liquid packaging product, the method further comprises:
the predetermined position is shaped as an insert hole for cooperation with a predetermined sterile insert.
It can be understood that by forming the insert hole at a predetermined position of the liquid-packed product in advance, the stability and reliability of the insertion of the predetermined aseptic insert can be ensured; therefore, when the preset sterile insert is inserted, the preset sterile insert is directly inserted into the insertion hole matched with the preset sterile insert.
For example, when the preset aseptic insert is a sterile rubber plug which can be used for puncturing a seal for multiple times, the preset position is formed into an inserting hole matched with the preset aseptic insert, and the preset aseptic insert comprises the following steps:
when liquid with preset dosage is filled into the liquid packaging product, the neck of the liquid packaging product is formed into a rubber plug embedding hole matched with the sterile rubber plug by utilizing an embedding forming die at the end part of the filling pipe.
That is to say, this embodiment is through the neck shaping plug embedding hole at liquid packaging article, and the embedding of adaptation aseptic plug, when embedding this aseptic plug, directly can in inserting the plug embedding hole with aseptic plug.
Simultaneously, this embodiment utilizes the setting to come to carry out the shaping to plug embedding hole at the embedding moulded die of filling tube tip, promptly, when the filling tube is to liquid packaging in the filling liquid, realizes the shaping in plug embedding hole, has simplified the process steps, has improved production efficiency.
Referring to fig. 2 to 6, fig. 2 is a schematic diagram showing a relative position of a partial structure of an apparatus for manufacturing a liquid packaging product according to an embodiment of the present invention; FIG. 3 is a top view of the sterile transfer cask and enclosed shaker tray of FIG. 2; FIG. 4 is a cross-sectional view of the process of filling the liquid into the liquid package; FIG. 5 is a cross-sectional view of a pre-sterile insert insertion process; fig. 6 is a cross-sectional view of a pre-set sterile insert being inserted into a liquid package.
In addition to the above-described liquid package manufacturing method, the present invention also provides a liquid package manufacturing apparatus for implementing the liquid package manufacturing method disclosed in the above-described embodiment, the liquid package manufacturing apparatus including an extruding device, a filling device, an inserting device 2, a main die 1, a head die 3, a control system, and the like.
Specifically, the extrusion apparatus is used for extruding a tube blank for forming a liquid package at a temperature and pressure, the tube blank having a wall thickness and a diameter required for forming the liquid package; the main die 1 is used for forming the tube blank extruded by the extruding device into the main body shape of the liquid packaging product when the tube blank is closed; the filling device is used for filling liquid with preset dosage into the liquid packaging product; the embedding device 2 is used for embedding a preset sterile embedding piece into a preset position of the liquid packaging product; the head die 3 is used for sealing the liquid pack when closed.
The control system is respectively connected with the actuating mechanisms of the extruding device, the filling device, the embedding device 2, the main die 1 and the head die 3, so that the extruding device, the filling device, the embedding device 2, the main die 1 and the head die 3 are controlled by the control system to work in a coordinated and orderly manner, and the whole process of forming, filling, embedding and sealing the container is completed.
It should be noted that the specific structures and shapes of the extruding device, the filling device, the embedding device 2, the main die 1, and the head die 3 are not specifically limited, and those skilled in the art can refer to the prior art or set according to actual needs as long as they can implement their respective corresponding functional actions.
Further, the connection manner of the extrusion device, the filling device, the embedding device 2, the main die 1 and the head die 3 with the control system is not particularly limited, and those skilled in the art can refer to the prior art.
Therefore, the manufacturing equipment of the liquid packaging product provided by the invention can realize the whole processes of container forming, filling, embedding and sealing of the liquid packaging product through the coordinated and orderly matched work of the extruding device, the filling device, the embedding device 2, the main die 1 and the head die 3 under the control of the control system. Compared with the blowing, filling and sealing integrated machine in the prior art, the manufacturing equipment of the liquid packaging product enables the preset sterile embedded part and the liquid packaging product to be in an integrated structure, and meets the sterile use requirement of the liquid packaging product by matching the preset sterile embedded part with the liquid packaging product; in addition, the preset sterile insert is prevented from being implanted in the later-stage use process, so that the temporary assembly process of the preset sterile insert and the liquid packaging product in the later-stage use process is avoided, and further the liquid is prevented from being polluted in the later-stage temporary assembly process.
On the basis of the above-described embodiment, the end of the filling tube 4 of the filling device is provided with an insert molding die 41 for molding a predetermined position of the liquid package as an insert hole adapted to a predetermined sterile insert.
That is, the present embodiment employs the insert-molding die 41 provided at the end of the filling tube 4 to mold an insert hole for fitting with a preset aseptic insert to install the preset aseptic insert. When the filling device fills the liquid in the liquid-packed product, the filling tube 4 is moved down to the filling position to fill the liquid-packed product with a predetermined amount of liquid, and at the same time, the insert molding die 41 at the end of the filling tube 4 forms the predetermined position of the liquid-packed product into the insert hole.
When the preset sterile embedded part is embedded, the preset sterile embedded part is directly inserted into the embedding hole.
It will be appreciated that the insert molding die 41 is the same shape and size as the pre-sterile insert, which ensures effective sealing of the liquid packaging after thermoforming and cold shrinking.
In view of the stability and reliability of the insert molding die 41 in molding the predetermined position of the liquid-packed product, on the basis of the above-described embodiment, the predetermined sterile insert is the sterile rubber plug 5, the insert molding die 41 includes the insertion portion corresponding to the plug of the sterile rubber plug 5, and the main die 1 is provided with the insert neck die 11 for guiding the insertion portion.
It can be understood that the insert neck mold 11 may form a first molding surface having the same shape as the insert neck mold 11 at a corresponding position of the liquid package, and during the process of molding the preset position of the liquid package by the insert molding mold 41, the inserting portion of the insert molding mold 41 moves along the first molding surface, on the one hand, the insert neck mold 11 guides the inserting portion of the insert molding mold 41; on the other hand, the embedded neck mold 11 enables the first molding surface formed at the corresponding position of the liquid packaging product to be in fit contact with the plug head of the sterile rubber plug 5, and the first-stage sealing effect is achieved.
On the basis of the above embodiment, the aseptic rubber stopper 5 comprises a cap connected to the stopper head, and the head die 3 is provided with a head die rubber stopper die 31 for molding the liquid packaging product into a second molding surface having the same outer contour as that of the cap.
It will be appreciated that the size of the head mold plug mold 31 is the sum of the size of the outer contour of the cap of the aseptic plug 5 and the size of the wall thickness of the liquid pack required to form the second-stage sealing of the second molding surface thereof with the outer contour of the cap of the aseptic plug 5 after the liquid pack is thermoformed and cold shrunk.
Further, the head die 3 is also provided with a necking die connected with the head die rubber plug die 31, and the size of the necking die is smaller than that of the head die rubber plug die 31, so that the sterile rubber plug 5 is effectively fixed with the liquid packaging product, and the sterile rubber plug 5 is prevented from sealing failure due to the movement of the sterile rubber plug 5 after the first use.
In view of the specific implementation of the embedding device 2, on the basis of any one of the above embodiments, the embedding device 2 includes an embedding suction pipe 21, a first driving mechanism and a second driving mechanism, the embedding suction pipe 21 is used for sucking the preset sterile embedding piece, a vacuum channel is arranged inside the embedding suction pipe 21, so that the inside of the embedding suction pipe 21 is vacuumized, and the preset sterile embedding piece is sucked by using vacuum negative pressure suction; the embedding straw 21 is respectively connected with a first driving mechanism and a second driving mechanism, and the first driving mechanism is used for driving the embedding straw 21 to move between a material taking position of a preset sterile embedding part and an embedding position of the preset sterile embedding part; the second driving mechanism is used for driving the embedding suction pipe 21 to lift so as to realize material taking or embedding of a preset sterile embedding piece.
Preferably, the insertion device 2 further comprises a guide rail 22 for guiding the movement of the insertion straw 21, the insertion straw 21 being connected to the guide rail 22 by means of a slide 23 slidable along the guide rail 22.
When the liquid packaging product manufacturing equipment is in a preset sterile insert embedding stage, the first driving mechanism drives the embedding suction pipe 21 to move to a material taking position, and the second driving mechanism drives the embedding suction pipe 21 to move downwards to suck a preset sterile insert; then, the second driving mechanism drives the embedding suction pipe 21 to rise to the original height position, the first driving mechanism drives the embedding suction pipe 21 to move to the embedding position, the second driving mechanism drives the embedding suction pipe 21 to move downwards, and the preset sterile embedding piece sucked by the embedding suction pipe 21 is embedded into the preset position of the liquid packaging product.
It will be appreciated that the use of the insertion straw 21 to aspirate the sterile pre-insert avoids wear or damage to the sterile pre-insert.
The specific structures of the first driving mechanism and the second driving mechanism are not limited in the present invention, and those skilled in the art can set the structures according to actual needs.
On the basis of the above-mentioned embodiment, still include aseptic transport bucket 6 and closed vibrations dish 7, aseptic transport bucket 6 is used for loading and predetermines aseptic embedding piece, aseptic transport bucket 6 and closed vibrations dish 7 link to each other through αβ valves to realize predetermineeing the aseptic transfer of aseptic embedding piece, with aseptic transport bucket 6 internal loading predetermine aseptic embedding piece aseptic transfer to closed vibrations dish 7 in, closed vibrations dish 7 can be with predetermineeing aseptic embedding piece neatly arranged's output to getting the material position, so that embedding straw 21 absorbs predetermineeing aseptic embedding piece.
Specifically, the αβ valves include αβ valve active valve 71 and αβ valve passive valve 61, αβ valve active valve 71 is located on closed shock disk 7, and αβ valve passive valve 61 is located on sterile transfer drum 6.
Preferably, a discharging pipe 75 for discharging the preset sterile inserts in order is arranged at an outlet of the closed vibration disc 7, and a material taking position is arranged at the tail end, far away from the closed vibration disc 7, of the discharging pipe 75.
In order to ensure sterility of the interior of closed vibratory pan 7, closed vibratory pan 7 is provided with a sterile wind inlet line 72 for introducing sterile wind of a constant flow rate and a constant positive pressure into closed vibratory pan 7, sterile wind inlet line 72 being provided with a sterilizing grade filter 73 and a precision pressure reducing valve 74, in addition to the above-described embodiments.
That is, in the present embodiment, the sterile wind is introduced into the closed vibration plate 7 through the sterile wind inlet pipeline 72, so that the inside of the closed vibration plate 7 is in a positive pressure state, thereby preventing the introduction of the bacteria into the closed vibration plate 7 and ensuring the sterility of the inside of the closed vibration plate 7.
It is further noted that, in the present specification, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions.
The embodiments are described in a progressive manner in the specification, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The process for producing the liquid packaging material and the apparatus for producing the same according to the present invention are described in detail above. The principles and embodiments of the present invention are explained herein using specific examples, which are presented only to assist in understanding the method and its core concepts. It should be noted that, for those skilled in the art, it is possible to make various improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the scope of the claims of the present invention.
Claims (10)
1. A process for the manufacture of a liquid package, comprising:
extruding a tube blank for forming a liquid package and into an open mold comprising a main mold and a head mold, closing the main mold to form the liquid package;
filling a preset dosage of liquid into the liquid packaging product;
inserting a predetermined sterile insert into a predetermined location of said liquid package;
and closing the head die and sealing the liquid packaging product.
2. A process for preparing a liquid package according to claim 1, wherein the predetermined sterile insert comprises a sterile rubber plug which can be used by multiple piercing, a flow restriction element or a needle for limiting the amount of liquid.
3. A process of manufacturing a liquid package according to claim 1 or 2, further comprising, before said inserting a predetermined sterile insert into a predetermined position of said liquid package:
and forming the preset position into an embedding hole matched with the preset sterile embedding piece.
4. An apparatus for manufacturing liquid packages, comprising:
an extruding device for extruding a tube blank for forming a liquid package;
a master mold (1) for forming the liquid package when closed;
a filling device for filling a predetermined amount of liquid into the liquid package;
an inserting device (2) for inserting a predetermined sterile insert into a predetermined position of said liquid packaging;
a head die (3) for closing the liquid pack when closed;
and the control systems are respectively connected with the actuating mechanisms of the extruding device, the filling device, the embedding device (2), the main die (1) and the head die (3) so as to control the extruding device, the filling device, the embedding device (2), the main die (1) and the head die (3) to coordinate and orderly move to complete the forming, filling, embedding and sealing of the container.
5. A liquid package manufacturing apparatus according to claim 4, wherein an end of the filling tube (4) of the filling device is provided with an insert molding die (41) for molding the predetermined position as an insert hole adapted to the predetermined aseptic insert.
6. The apparatus for manufacturing liquid packages according to claim 5, wherein the preset aseptic insertion member is an aseptic rubber plug (5), the insert molding die (41) includes an insertion portion corresponding to a plug head of the aseptic rubber plug (5), and the main die (1) is provided with an insertion neck die (11) for guiding the insertion portion.
7. The apparatus for manufacturing liquid-packaged products according to claim 6, wherein the aseptic plug (5) comprises a cap connected to the stopper, and the head die (3) is provided with a head-die plug die (31) for molding the liquid-packaged products into a second molding surface having the same outer contour as that of the cap.
8. A liquid packaging producing apparatus according to any one of claims 4-7, wherein said inserting means (2) comprises:
an insert straw (21) for sucking the preset sterile insert, wherein a vacuum channel is arranged inside the insert straw (21);
the first driving mechanism is connected with the embedding straw (21) and is used for driving the embedding straw (21) to move between the material taking position of the preset sterile embedding piece and the embedding position of the preset sterile embedding piece;
and the second driving mechanism is connected with the embedding suction pipe (21) and is used for driving the embedding suction pipe (21) to lift so as to realize material taking or embedding of the preset sterile embedding piece.
9. The apparatus for manufacturing a liquid-packed product according to claim 8, further comprising:
an aseptic transfer drum (6) for loading said preset aseptic inserts;
a closed vibrating disk (7) connected to the sterile transfer drum (6) through an αβ valve.
10. The apparatus for manufacturing liquid packages according to claim 9, wherein said closed shaker pan (7) is provided with a sterile wind inlet line (72) for feeding sterile wind of a stable flow rate and a stable positive pressure into said closed shaker pan (7), said sterile wind inlet line (72) being provided with a sterilizing grade filter (73) and a fine pressure reducing valve (74).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911134570.9A CN110861330B (en) | 2019-11-19 | 2019-11-19 | Process method and manufacturing equipment for liquid packaging product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911134570.9A CN110861330B (en) | 2019-11-19 | 2019-11-19 | Process method and manufacturing equipment for liquid packaging product |
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| CN110861330B (en) | 2021-11-09 |
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Denomination of invention: A process method and manufacturing equipment for liquid packaging Effective date of registration: 20221212 Granted publication date: 20211109 Pledgee: Zibo sub branch of qishang Bank Co.,Ltd. Pledgor: Shinva Medical Instrument Co.,Ltd. Registration number: Y2022980026499 |
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