CN110859656A - Water flow replacement thrombus suction device - Google Patents

Water flow replacement thrombus suction device Download PDF

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Publication number
CN110859656A
CN110859656A CN201911147497.9A CN201911147497A CN110859656A CN 110859656 A CN110859656 A CN 110859656A CN 201911147497 A CN201911147497 A CN 201911147497A CN 110859656 A CN110859656 A CN 110859656A
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CN
China
Prior art keywords
thrombus
occluder
water flow
diameter
recovery tube
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911147497.9A
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Chinese (zh)
Inventor
宋浩
祝缓缓
杨青林
王泱
朱幼宁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kunshan Jintai Medical Technology Co Ltd
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Kunshan Jintai Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority to CN201911147497.9A priority Critical patent/CN110859656A/en
Publication of CN110859656A publication Critical patent/CN110859656A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • A61B2017/22025Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement applying a shock wave
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22079Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris

Abstract

The present invention relates to a water flow replacement thrombus aspiration device, comprising: a first occluding device; a second stopper corresponding to the first stopper; the high-pressure injection pipe penetrates through the first plugging device and the second plugging device and is connected with two ends of the first plugging device; the plurality of injection holes are formed in the outer surface of the high-pressure injection pipe; and a thrombus mixture recovery tube surrounding the high-pressure injection tube. The high-pressure water flow disclosed by the invention is sprayed out of the spray holes of the stainless steel pipe, so that thrombus can be quickly and efficiently broken, and finally the thrombus is recovered to the outside of the body through the thrombus mixed liquid recovery pipe, so that the thrombus is more efficiently sucked, and the thrombus suction device is simple in structure and easy to operate.

Description

Water flow replacement thrombus suction device
FIELD
The invention relates to the technical field of medical instruments, in particular to a water flow replacement thrombus suction device.
Background
Peripheral Arterial Disease (PAD) includes a series of non-coronary systemic syndromes caused by structural and functional changes in the arteries supplying the brain, internal organs and limbs, i.e., stenosis, occlusion or neoplastic-like expansion of the aorta and its branches other than the coronary arteries. Multiple pathophysiological mechanisms can lead to stenosis or neoplasia of these non-coronary blood circulation, but atherosclerosis remains a major cause of involvement of the aorta and branch arteries. With the development of the intracavity treatment technology and interventional instrument technology, Percutaneous Transluminal Angioplasty (PTA) has become an important treatment means for ischemic diseases of lower limbs, however, the long-term restenosis rate of PTA reaches about 40%, which becomes a development bottleneck of the technology, and is unavoidable and unresolved; in recent years, thrombus volume reduction technology (TDT) is proposed in the development of peripheral vascular therapy technology, and TDT is an important surgical auxiliary treatment means. Can effectively save medical cost, improve cure rate and reduce pain, disability rate and fatality rate of patients. Mechanical thrombus removal pmt (transient thrombus) is the most advanced and effective peripheral arterial and venous thrombus volume reduction technology at present, however, when a thrombus removal operation is performed, a diseased blood vessel can be injured, so that mechanical thrombus removal is required to achieve the aims of breaking thrombus and reducing thrombus flow as far as possible, thereby threatening life and reducing complications.
SUMMARY
The present disclosure relates to a water flow replacement thrombus aspiration device, comprising:
a first occluding device;
a second stopper corresponding to the first stopper;
the high-pressure injection pipe penetrates through the first plugging device and the second plugging device and is connected with two ends of the first plugging device;
the plurality of injection holes are formed in the outer surface of the high-pressure injection pipe; and
and the thrombus mixed liquid recovery pipe surrounds the high-pressure injection pipe.
Brief description of the drawings
Figure 1 illustrates an aqueous replacement thrombus aspiration device configuration according to certain embodiments of the present disclosure.
Figure 2 illustrates a functional diagram of an aqueous replacement thrombus extraction device according to certain embodiments of the present disclosure.
Detailed description of the invention
In the following description, certain specific details are included to provide a thorough understanding of various disclosed embodiments. One skilled in the relevant art will recognize, however, that the embodiments can be practiced without one or more of the specific details, or with other methods, components, materials, and so forth.
Unless otherwise required by the disclosure, throughout the specification and the appended claims, the words "comprise", "comprising", and "have" are to be construed in an open, inclusive sense, i.e., "including but not limited to".
Reference throughout the specification to "one embodiment," "an embodiment," "in another embodiment," or "in certain embodiments" means that a particular reference element, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of the phrases "in one embodiment" or "in an embodiment" or "in another embodiment" or "in certain embodiments" in various places throughout this specification are not necessarily all referring to the same embodiment, and furthermore, particular elements, structures, or features may be combined in any suitable manner in one or more embodiments.
Definition of
In the present disclosure, the term "occluder" is an interventional implant for occluding a diseased area.
In the present disclosure, the term "covered nickel titanium alloy stent" has the advantages of uniform expansion force and good compliance, and is used for treating pathological changes.
In the present disclosure, the term "t-PA" belongs to the serine class of proteins, with a more potent and specific thrombolytic effect.
In the present disclosure, the term "rt-PA" is a single-chain, aglycosylated t-PA deletion mutant that freely diffuses into the clot, promoting the conversion of plasminogen to active plasmin, degrading fibrin in the thrombus, and exerting a thrombolytic effect.
In the present disclosure, the term "SaK" is a 136 amino acid residues polypeptide secreted by staphylococcus aureus, and has the advantages of small molecular weight, high specificity, no pathological reaction, safe therapeutic effect, etc.
Detailed Description
The present disclosure relates to a water flow replacement thrombus aspiration device, comprising:
a first occluding device;
a second stopper corresponding to the first stopper;
the high-pressure injection pipe penetrates through the first plugging device and the second plugging device and is connected with two ends of the first plugging device;
the plurality of injection holes are formed in the outer surface of the high-pressure injection pipe; and
and the thrombus mixed liquid recovery pipe surrounds the high-pressure injection pipe.
In certain embodiments, the first occluder is frustoconical.
In some embodiments, the first occluding device comprises a first bottom surface and a second bottom surface.
In certain embodiments, the first base diameter is less than the second base diameter.
In certain embodiments, the first occluder is hollow.
In certain embodiments, the second occluder is frustoconical.
In certain embodiments, the second occluding device comprises a third bottom surface and a fourth bottom surface.
In certain embodiments, the third base diameter is less than the fourth base diameter.
In certain embodiments, the second occluder is hollow.
In certain embodiments, the second bottom surface of the first stopper and the fourth bottom surface of the second stopper have the same diameter.
In certain embodiments, the first occluding device is selected from a covered nitinol stent.
In certain embodiments, the second occluding device is selected from a covered nitinol stent.
In certain embodiments, a mixed thrombus fluid recovery tube is connected to the second occluding device.
In certain embodiments, the thrombus mixture recovery tube is cylindrical.
In certain embodiments, the thrombus mixture recovery tube is hollow.
In certain embodiments, the diameter of the bottom surface of the mixed thrombus fluid recovery tube is equal to the diameter of the first bottom surface of the second occluder.
In the thrombus suction process, due to the action of the first plugging device and the second plugging device, thrombus cannot flow to other parts of a human body, side effects on the human body cannot be generated, and life threat caused by thrombus flow cannot be generated.
In certain embodiments, the high pressure injection tube is cylindrical.
In certain embodiments, the high pressure injection tube is stainless steel.
In certain embodiments, the high pressure injection tube has a diameter of 0.3 to 0.5 mm.
In certain embodiments, the high pressure injection tube has an operating length of 30 to 50 mm.
In certain embodiments, the high pressure jet tube diameter is less than the thrombus mixture recovery tube diameter.
In certain embodiments, the high pressure injection tube is hollow.
In certain embodiments, the injection orifices are circular, oval, rectangular, or triangular.
In certain embodiments, the injection holes are circular.
In certain embodiments, the jet orifice diameter is 0.05 to 0.1 mm.
In certain embodiments, the spray orifices are equally spaced on the exterior surface of the high pressure spray tube.
In certain embodiments, the equidistant distance is from 1 to 10 mm.
In certain embodiments, the high pressure water is selected from high pressure physiological saline or thrombolytic drug solutions.
In certain embodiments, the thrombolytic drug solution is selected from t-PA, rt-PA, SaK, or mixtures thereof.
In certain embodiments, the injection pressure of the injection hole is 1 to 20 MPa.
Wherein, a plurality of jet orifices of high-pressure pipe injection pipe spray high-pressure rivers simultaneously, direct action is on pathological change department thrombus, makes thrombus suction efficiency higher.
In certain embodiments, a stopper recovery tube is also included.
In certain embodiments, the occluder recovery tube is connected to a mixed thrombus fluid recovery tube.
In certain embodiments, the occluder recovery tube is cylindrical.
In certain embodiments, the occluder recovery tube is hollow.
In certain embodiments, the diameter of the occluder recovery tube is greater than the diameter of the thrombus mixture recovery tube.
Example 1
As shown in figure 1, the water flow replacement thrombus suction device structure comprises: the device comprises a first occluder 1, a second occluder 2, a high-pressure injection pipe 3, an injection hole 4, a thrombus mixed liquid recovery pipe 5 and an occluder recovery pipe 6.
The high-pressure injection pipe 3 passes through the first plugging device 1 and the second plugging device 2 and is connected with two ends of the first plugging device 1, wherein the first plugging device 1 corresponds to the second plugging device 2, the injection holes 4 are formed in the outer surface of the high-pressure injection pipe 3, the thrombus mixed liquid recovery pipe 5 is distributed around the high-pressure injection pipe 3, the thrombus mixed liquid recovery pipe 5 is connected with the second plugging device 2, and the plugging device recovery pipe 6 is connected with the thrombus mixed liquid recovery pipe 5.
As shown in fig. 2, the working principle diagram of the water flow replacement thrombus suction device comprises: vessel wall 7, thrombus 8.
When the sheath is sent to the front end of lesion about 2mm, the sheath of the first occluder 1 is pulled back, the first occluder 1 is made to release and bounce open, the vascular wall 7 is occluded, then, the sheath is pulled back, when the end of the thrombus lesion 8 is reached, the sheath of the second occluder 2 is pulled back, the second occluder 2 is made to release and bounce open, the vascular wall 7 is occluded, at the moment, the high-pressure jet pipe 3 at the center jets high-pressure water flow, the high-pressure water flow of the plurality of jet holes 4 can directly break thrombus 8, due to the complete occlusion of the first occluder 1 and the second occluder 2, redundant waste liquid can flush to the outside along the thrombus mixed liquid recovery pipe 5, after the operation is completed, the first occluder 1 and the second occluder 2 are pulled back to the occluder recovery pipe 6, the high-pressure jet pipe 3 is recovered to the sheath, and the high-pressure jet pipe is withdrawn outside the body.
The water flow replacement thrombus suction device provided by the invention overcomes the defect of low thrombus removal rate in the existing mechanical thrombus removal treatment, high-pressure water flow is sprayed out from the spray hole of the stainless steel pipe to directly act on a lesion site, so that thrombus can be quickly and efficiently broken, and the broken thrombus can be finally recovered to the outside of a body through the thrombus mixed liquid recovery pipe, so that the thrombus suction is more efficient. The thrombus suction device has simple structure and easy operation.
From the foregoing it will be appreciated that, although specific embodiments of the disclosure have been described herein for purposes of illustration, various modifications or improvements may be made by those skilled in the art without departing from the spirit and scope of the disclosure, and that such modifications or improvements are intended to be within the scope of the appended claims.

Claims (9)

1. An aquareplacement thrombus aspiration device comprising:
a first occluding device;
a second stopper corresponding to the first stopper;
the high-pressure injection pipe penetrates through the first plugging device and the second plugging device and is connected with two ends of the first plugging device;
the plurality of injection holes are formed in the outer surface of the high-pressure injection pipe; and
and the thrombus mixed liquid recovery pipe surrounds the high-pressure injection pipe.
2. The water flow replacement thrombus aspiration device of claim 1, wherein the first occluder is frustoconical, the first occluder comprising a first base surface and a second base surface, preferably the first base surface having a diameter smaller than the second base surface, more preferably the first occluder is hollow.
3. The water flow replacement thrombus aspiration device of claim 1 or 2, wherein the second occluder is frustoconical, the second occluder comprises a third base surface and a fourth base surface, preferably the third base surface has a diameter smaller than the fourth base surface, more preferably the second occluder is hollow, more preferably the first occluder second base surface and the second occluder fourth base surface have the same diameter.
4. The water flow replacement thrombus aspiration device of any one of claims 1 to 3 wherein the first occluder is selected from a coated nitinol stent and the second occluder is selected from a coated nitinol stent.
5. The water flow replacement thrombus aspiration device according to claim 4, wherein the thrombus mixture recovery tube is connected to the second occluder, preferably the thrombus mixture recovery tube has a cylindrical shape, more preferably the thrombus mixture recovery tube has a hollow shape, and more preferably the bottom surface diameter of the thrombus mixture recovery tube is equal to the first bottom surface diameter of the second occluder.
6. The water current replacement thrombus aspiration device according to claim 4 or 5, wherein the high pressure injection tube is cylindrical, the diameter of the high pressure injection tube is 0.3 to 0.5mm, the working length of the high pressure injection tube is 30 to 50mm, preferably the diameter of the high pressure injection tube is smaller than the diameter of the thrombus mixture recovery tube, and preferably the high pressure injection tube is hollow.
7. The water flow replacement thrombus aspiration device of any one of claims 4 to 6 wherein: the injection hole is circular, oval, rectangular or triangular, preferably circular, and more preferably the diameter of the injection hole is 0.05-0.1 mm; the spraying holes are distributed on the outer surface of the high-pressure spraying pipe at equal intervals, and the preferred equal interval distance is 1-10 mm.
8. The water flow replacement thrombus aspiration device of any one of claims 1 to 7 wherein:
the high-pressure water is selected from high-pressure physiological saline or thrombolytic liquid medicine, and preferably the thrombolytic liquid medicine is selected from t-PA, rt-PA, SaK or a mixture thereof;
the injection pressure of the injection hole is 1 to 20 MPa.
9. The water flow replacement thrombus aspiration device according to claim 8, further comprising an occluder recovery tube connected to the thrombus mixture recovery tube, preferably the occluder recovery tube has a cylindrical shape, more preferably the occluder recovery tube has a hollow shape, and more preferably the occluder recovery tube has a diameter larger than the thrombus mixture recovery tube.
CN201911147497.9A 2019-11-21 2019-11-21 Water flow replacement thrombus suction device Pending CN110859656A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111904540A (en) * 2020-09-07 2020-11-10 泓懿医疗器械(苏州)有限公司 Device for taking out thrombus attached to wall in blood vessel and using method thereof

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2049956U (en) * 1989-07-28 1989-12-27 王东亚 Guide tube for removing thrombus in blood vessel
US5011488A (en) * 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
US20030073953A1 (en) * 1999-12-10 2003-04-17 Hans Mische Dual syringe and methods
US20060064123A1 (en) * 1998-02-06 2006-03-23 Possis Medical, Inc. Rapid exchange fluid jet thrombectomy device and method
CN203354604U (en) * 2013-07-23 2013-12-25 李长江 Thrombus aspiration catheter
CN104434258A (en) * 2014-11-28 2015-03-25 苏州亘科医疗科技有限公司 Multifunctional balloon dilatation catheter
CN204723106U (en) * 2015-06-02 2015-10-28 中国人民解放军第四军医大学 A kind of stopper gets involved retracting device
CN105395238A (en) * 2015-12-14 2016-03-16 天津大学 Intravascular plaque removal device and method
CN105496507A (en) * 2016-01-30 2016-04-20 李新民 Device for dredging cardio-cerebral vessels and cleaning vascular thrombosis
US20170100142A1 (en) * 2015-10-09 2017-04-13 Incuvate, Llc Systems and methods for management of thrombosis
CN107262465A (en) * 2017-05-27 2017-10-20 董涛 Equipment is removed in visualization in pipeline
CN107510491A (en) * 2017-08-25 2017-12-26 江西理工大学 Thrombus Crusher
CN207384299U (en) * 2017-03-13 2018-05-22 天津市塑料研究所有限公司 There is the conduit of Biochemical analyzer
CN109259819A (en) * 2018-07-26 2019-01-25 河南亚都实业有限公司 A kind of novel aspirate thrombi conduit and its system
CN208822863U (en) * 2018-03-28 2019-05-07 首都医科大学附属北京儿童医院 A kind of right side bronchi plugging catheter
CN109965939A (en) * 2019-04-13 2019-07-05 刘维英 A kind of removing thrombus device

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011488A (en) * 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
CN2049956U (en) * 1989-07-28 1989-12-27 王东亚 Guide tube for removing thrombus in blood vessel
US20060064123A1 (en) * 1998-02-06 2006-03-23 Possis Medical, Inc. Rapid exchange fluid jet thrombectomy device and method
US20030073953A1 (en) * 1999-12-10 2003-04-17 Hans Mische Dual syringe and methods
CN203354604U (en) * 2013-07-23 2013-12-25 李长江 Thrombus aspiration catheter
CN104434258A (en) * 2014-11-28 2015-03-25 苏州亘科医疗科技有限公司 Multifunctional balloon dilatation catheter
CN204723106U (en) * 2015-06-02 2015-10-28 中国人民解放军第四军医大学 A kind of stopper gets involved retracting device
US20170100142A1 (en) * 2015-10-09 2017-04-13 Incuvate, Llc Systems and methods for management of thrombosis
CN105395238A (en) * 2015-12-14 2016-03-16 天津大学 Intravascular plaque removal device and method
CN105496507A (en) * 2016-01-30 2016-04-20 李新民 Device for dredging cardio-cerebral vessels and cleaning vascular thrombosis
CN207384299U (en) * 2017-03-13 2018-05-22 天津市塑料研究所有限公司 There is the conduit of Biochemical analyzer
CN107262465A (en) * 2017-05-27 2017-10-20 董涛 Equipment is removed in visualization in pipeline
CN107510491A (en) * 2017-08-25 2017-12-26 江西理工大学 Thrombus Crusher
CN208822863U (en) * 2018-03-28 2019-05-07 首都医科大学附属北京儿童医院 A kind of right side bronchi plugging catheter
CN109259819A (en) * 2018-07-26 2019-01-25 河南亚都实业有限公司 A kind of novel aspirate thrombi conduit and its system
CN109965939A (en) * 2019-04-13 2019-07-05 刘维英 A kind of removing thrombus device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111904540A (en) * 2020-09-07 2020-11-10 泓懿医疗器械(苏州)有限公司 Device for taking out thrombus attached to wall in blood vessel and using method thereof

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Application publication date: 20200306