Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, the present invention claims a modular block diagram of an interventional therapeutic scanning imaging system.
The invention relates to an interventional therapy scanning imaging system, which is characterized by comprising the following modules according to the working flow chart of the interventional therapy scanning imaging system with reference to the attached figure 2:
the interventional therapy data reading module is responsible for reading in interventional therapy image data, supports image files in JPG and IMG formats besides files in DICOM format, unifies the image files into intermediate data in the same format, excites to obtain interventional therapy signals, and delivers the interventional therapy signals to the image preprocessing module for processing;
the image preprocessing module is used for preprocessing each slice of the medical data according to the operation of a user after the medical data transmitted by the interventional therapy data reading module is obtained, and the preprocessing comprises filtering, enhancing, registering, cutting a three-dimensional ultrasonic image, denoising and binaryzation;
the three-dimensional imaging module is used for imaging the preprocessed medical slice into a three-dimensional stereo model, and realizing the segmentation of a specific tissue by adopting a segmentation method combining binaryzation and morphology through algorithms such as volume imaging or surface imaging and the like according to the requirements of doctors so as to realize the imaging of the specific tissue;
the system comprises an interventional interactive module, a system and a display module, wherein the interventional interactive module adopts interactive volume data imaging, a user performs rotation, zooming and translation operations on an imaged three-dimensional model, and the system displays the operation effect through the modules and can switch among different views.
Furthermore, the interventional therapy data reading module is responsible for reading in interventional therapy image data, supports image files in the JPG and IMG formats in addition to files in the DICOM format, unifies the image files into intermediate data in the same format, excites and obtains interventional therapy signals, and delivers the interventional therapy signals to the image preprocessing module for processing, and the interventional therapy data reading module comprises:
the digital image of the biological tissue and organ is obtained by scanning the interventional therapy image data through medical imaging equipment;
interpolating between adjacent layers, representing the scanned interventional therapy image data as a sum of image information based on the interventional therapy image data in the sample library and interventional differentiation image information;
the data field is formed by the superposition of MRI and CT tomograms generated by a computer tomography scanner and nuclear magnetic resonance in one spatial direction;
obtaining interventional differentiation image information by utilizing parallel imaging, and forming sparse representation of scanned interventional treatment image data through a multi-coil model coefficient of the interventional image body and a coefficient of the interventional differentiation image information in a sparse transform domain; the data field data is abstracted into a three-dimensional array obtained by uniformly sampling objects defined in a three-dimensional closed space, including organism tissues and organs;
constructing an interventional image volume according to the reference prior information, and capturing image information based on interventional treatment image data in a sample library through the interventional image volume;
interventional therapy image data jointly utilizing an interventional image volume, parallel imaging and an objective function enhanced sparse imaging scan.
Further, after obtaining the medical data transmitted by the interventional therapy data reading module, the image preprocessing module preprocesses each slice of the medical data according to the operation of the user, where the preprocessing includes filtering, enhancing, registering, three-dimensional ultrasound image clipping, denoising, and binarization, and specifically includes:
adopting a sliding window containing odd points, and replacing the gray value of the central point of the window with the gray value median of each point in the window;
automatically selecting the best matching template according to the conditions of each pixel point on the image and 8 adjacent points around the pixel point to process, identify and judge so as to decide whether to reserve or filter;
for odd elements, the median refers to a numerical value in the middle after sorting according to size, and for even elements, the median refers to an average value of gray values of two middle elements after sorting;
the image is blurred by means of average and integral operation, and the image can be subjected to inverse operation by adopting a method of using a template and counting difference values by a differential operator, so that the image is enhanced and sharpened;
automatically transforming and correcting the coordinates of each pixel in the image by using a nearest neighbor gray interpolation method to obtain an original image after coordinate adjustment and a target classification image thereof, thereby obtaining a sequence two-dimensional slice image after registration;
setting the pixel (voxel) of the three-dimensional medical image in the gray scale range required for extracting the tissue as 1, and setting the rest as 0, namely, performing binary processing on the three-dimensional medical image by using two threshold values (d1, d 2):
assuming that the input image is f (x, y, z) and the output image is f' (x, y, z), then
Designing a color transfer function and an opacity transfer function, setting an imager and creating an imaging window based on mapping relation construction body data and setting attributes including a difference mode and illumination parameters;
adopting a GPU to perform ray projection algorithm imaging, initiating an interaction request, readjusting the interaction request if parameters change, and otherwise closing a window;
finding out a threshold range in the gray statistical histogram, dividing the original image into a plurality of regions, modifying the division result by opening and closing operations, and finally separating out a specific target;
further, the three-dimensional imaging module images the preprocessed medical slice into a three-dimensional stereo model, and realizes the segmentation of the specific tissue by using a segmentation method combining binarization and morphology and algorithms such as volume imaging or area imaging according to the requirements of doctors to realize the imaging of the specific tissue, and specifically comprises:
carrying out image intrusive scanning by adopting a laser excitation signal to generate an intrusive optical signal, and collecting the intrusive optical signal by using a data acquisition card;
the light outlet end of the multi-state optical cable is tightly attached to the light inlet end face of the self-focusing lens, is detected by an image converter in the guide pipe, is converted into an ultrasonic electric signal by mechanical waves, and is subjected to signal amplification processing by an ultrasonic transceiver;
diverging light beams transmitted and emitted from the optical cable converge after passing through the self-focusing lens and are transmitted to the surface of the sample through the transmission surface of the transmission mirror to excite the photoacoustic signal;
the main trigger excitation signal synchronously acts on the delay plate and completes the excitation and the collection of the optical signal after a certain time delay;
the image converter is tightly attached to the right-angle surface of the transmission mirror, and the detection surface of the image converter is vertically upward, so that the direction of a sound field receiving area is consistent with the direction of a reference line of a sample photoacoustic signal excitation surface;
the matching pipe and the base in the imaging guide pipe are used for assisting in assembling the guide pipe and arranging internal components, and the metal pipe is provided with an imaging window in the image converter and the transmission lens area;
when the program enters the execution state, the code performs each specified function on one hand, and simultaneously detects an end signal on the other hand, if a signal for requesting the end of the program is received, the program jumps out of the loop, simultaneously jumps out of the state machine structure, cleans up the program code, and exits the program.
Specifically, an MSP430 single chip microcomputer is used as a lower computer platform, and ports coming out of the single chip microcomputer are respectively connected with a 532 laser instrument and a rotary motor driver, and the rotary motor driver mainly plays a role in time delay triggering. The MSP430 receives the excitation signal trigger signal from the tunable laser, counts the excitation signal trigger signal, and outputs an excitation signal to trigger the tunable laser or the rotating machine driver to operate after a certain time delay when the count reaches a set value. Assuming the initial band mean of the tunable laser is λ1The mean value of the stop band is lambda2The scanning step length of the wave band mean value is S, and the number of laser excitation signals emitted under each wave band mean value is m. The number of counts Q of the MSP430 over a set of spectral cycles is then
After the MSP430 outputs the trigger excitation signal outwards, the original excitation signal is counted and cleared immediately, and a new round of counting is started, so that the spectrum mode that the photoacoustic spectrum is scanned in motion by the fixed-point spectrum is realized.
Further, the interventional interaction module adopts interactive volume data imaging, the user performs operations of rotating, zooming and translating on the imaged three-dimensional model, and the system displays the operation effect through the modules and can switch between different views, specifically comprising:
updating records in a record table according to the operation result, wherein each record in the record table comprises a hash value, an operation parameter and operation times; judging whether the operation times of the updated record reach a maximum threshold value or not, if so, deleting the record in the record table, and moving the hash value and the operation parameters in the record to the hash operation list as storage items to update the hash operation list;
the operation result is distributed on the grid points of the uniform grid or the regular grid, namely the structured data of the uniform grid or the structured data of the regular grid, and then the discrete operation result is subjected to format conversion, redundant data elimination, required data derivation and other operations;
classifying the three-dimensional data voxel according to the difference of the numerical values, and finding out the corresponding relation between the data and different substances or different attributes;
the hash value of the operation effect is a hash digest value of the effective content of the hit interactive object, the operation parameter represents an operation result of the data issued by the user corresponding to the effective content of the hit interactive object, and the operation frequency is the frequency of obtaining the operation result of the data issued by the user corresponding to the effective content of the hit interactive object.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions, improvements, etc. within the spirit and principle of the present invention should be included in the scope of the present invention.