CN110812553A

CN110812553A - Implanted mechanical circulation auxiliary device in aorta

Info

Publication number: CN110812553A
Application number: CN201911079459.4A
Authority: CN
Inventors: 陈松; 王雪丽; 张长东; 孙明; 朱涛; 毛亮
Original assignee: Wuhan Wei Ke Medical Technology Co Ltd
Current assignee: Wuhan Wei Ke Medical Technology Co Ltd
Priority date: 2019-11-07
Filing date: 2019-11-07
Publication date: 2020-02-21

Abstract

The invention discloses an implanted mechanical circulation auxiliary device in aorta, comprising: the device comprises a power device, a driving device and a fixing device, wherein one end of the power device is connected with the driving device; the outer walls of the power device and the driving device are fixedly connected with the fixing device, or the outer wall of the power device is fixedly connected with the fixing device. The fixing device is fixed on the inner wall of the descending aorta vessel of the patient to be treated, so that the driving device drives the blood to flow. The aorta implanted mechanical circulation auxiliary device has a simple overall structure, and can be used for sending the whole device to the descending aorta position of a patient in an interventional operation mode, increasing the blood flow of blood flowing to each organ of the patient and meeting the blood supply of the organ; the operation risk is reduced, the application range is wide, and especially, the operation risk is high for patients who cannot be controlled by using medicines only.

Description

Implanted mechanical circulation auxiliary device in aorta

Technical Field

The invention relates to the technical field of structural design of heart auxiliary devices used by patients with heart failure, in particular to an implanted mechanical circulation auxiliary device in aorta.

Background

Heart failure (heart failure) refers to a heart circulatory disturbance syndrome caused by insufficient discharge of venous return blood volume from the heart due to the failure of the systolic function and/or diastolic function of the heart, resulting in venous system blood stasis and arterial system blood perfusion deficiency, wherein the disturbance syndrome is manifested as pulmonary congestion and vena cava congestion. Heart failure is not an independent disease but the terminal stage of progression of heart disease. Most of these heart failures begin with left heart failure, which manifests itself primarily as pulmonary circulation congestion.

For patients with NYHA three-level and early-stage heart failure, the patients who are not suitable for high-risk and high-cost cardiac surgery because of the simple use of drugs and the uncontrollable use of drugs are seriously not suitable for receiving operations such as heart transplantation or LVAD implantation (left ventricle assisted artificial heart) and the like through researches and experiments. And the implantation of the same type of instruments has a higher risk.

However, millions of patients are treated annually worldwide, and there are not good treatments for them, with around 30% of patients with late-stage heart failure leading to death.

Therefore, for NYHA three-level and early four-level heart failure patients and patients who cannot be controlled by using medicines and are not suitable for cardiac surgery, no good treatment equipment can be used.

Disclosure of Invention

In view of the above, the main objective of the present invention is to provide an intra-aortic implantable mechanical circulatory assist device which has low risk and is easy to operate and suitable for patients with various diseases.

In order to achieve the purpose, the technical scheme of the invention is realized as follows:

an intra-aortic implantable mechanical circulatory assist device, comprising: the device comprises a power device, a driving device and a fixing device, wherein one end of the power device is connected with the driving device.

In a preferred embodiment, the power unit and the drive unit are fixedly connected to the fixing device, or the power unit is fixedly connected to the fixing device.

In a preferred embodiment, the anchoring device is fixed to the inner wall of the descending aorta vessel of the patient to be treated, so that the driving device drives the blood flow.

In a preferred embodiment, the drive device comprises: the power output end of the power device is in driving connection with the driving impeller; the tail end of the blocking cylinder is fixedly connected with one end of a driving impeller connected with a power device through the connecting rod; the driving impeller is arranged in the blocking cylinder.

In a preferred embodiment, the fixing means comprises: a connecting part, a fixing part and a filtering part; two ends of the connecting part are respectively fixedly connected with the fixing part and the front end of the blocking barrel; the other end of the fixing part is connected with the filtering part; the other end of the filtering part is connected with one end of the power device, which is far away from the driving impeller.

In a preferred embodiment, three connecting rods are provided.

In a preferred embodiment, the connecting rods are of a mesh structure.

In a preferred embodiment, the blade ends of the drive impeller are each machined to a blunt configuration.

In a preferred embodiment, the connecting portion has an open structure.

In a preferred embodiment, the filter structure and the connecting structure are symmetrical.

In a preferred embodiment, the overall structure of the fixing portion is a cylindrical structure.

In a preferred embodiment, the filter portion has a semicircular arc shape.

In a preferred embodiment, the entire fixation device is woven from a memory metal, with the density being the most sparse at the connection and the density being the greatest at the filter.

Further preferably, the memory metal is nitinol wire.

In a preferred embodiment, the method further comprises: a power supply device; and the power output end of the power supply device is connected with the power input end of the power device.

In a preferred embodiment, the power supply device is arranged inside a housing of the power unit.

In a preferred embodiment, the power supply device is arranged under the axilla skin of the patient to be treated, and the power supply output end of the power supply device is connected with the power supply input end of the power device through a lead.

In a preferred embodiment, the power supply device comprises: the device comprises an internal antenna, a rectifying and smoothing circuit, a charging circuit and a battery; the internal antenna, the rectifying and smoothing circuit, the charging circuit and the battery are connected in sequence.

In a preferred embodiment, the power means is a magnetic drive.

The invention discloses an implanted mechanical circulation auxiliary device in aorta, which has the following beneficial effects:

the mechanical circulation auxiliary device of implantation in aorta includes: the device comprises a power device, a driving device and a fixing device, wherein one end of the power device is connected with the driving device; the outer walls of the power device and the driving device are fixedly connected with the fixing device, or the outer wall of the power device is fixedly connected with the fixing device. The fixing device is fixed on the inner wall of the descending aorta vessel of the patient to be treated, so that the driving device drives the blood to flow. The defect that no treatment equipment can be well used for patients with NYHA three-level and early four-level heart failure and patients who are not suitable for cardiac surgery and cannot be controlled by simply using medicaments in the prior art is overcome. The aorta implanted mechanical circulation auxiliary device has a simple overall structure, and can be used for sending the whole device to the descending aorta position of a patient in an interventional operation mode, increasing the blood flow of blood flowing to each organ of the patient and meeting the blood supply of the organ; the operation risk is reduced, the application range is wide, and especially, the operation risk is high for patients who cannot be controlled by using medicines only.

Drawings

FIG. 1 is a schematic external view of an implantable aortic mechanical circulatory assist device according to an embodiment of the present disclosure;

FIG. 2 is a schematic diagram illustrating the internal structure of the implantable aortic mechanical circulatory assist apparatus of FIG. 1 according to an embodiment of the present disclosure;

FIG. 3 is a schematic view of the internal structure of an implantable mechanical circulatory assist device in the aorta according to another embodiment of the present disclosure;

FIG. 4 is a schematic external view of an implantable aortic mechanical circulatory assist device according to yet another embodiment of the present disclosure;

FIG. 5 is a schematic diagram illustrating the internal structure of the implantable aortic mechanical circulatory assist apparatus of FIG. 4 according to yet another embodiment of the present disclosure;

FIG. 6 is a schematic view of the internal structure of an implantable aortic mechanical circulatory assist apparatus according to a fourth embodiment of the present disclosure;

fig. 7 is a schematic structural view of the aortic implantable mechanical circulatory assist device of fig. 6 when the baffle cylinder is cut open according to a fourth embodiment of the present disclosure.

[ description of main reference symbols ]

1. A power plant;

2. the device comprises a driving device 21, a driving impeller 22, a blocking cylinder 23 and a connecting rod;

3. fixing device 31, connecting part 32, fixing part 33 and filtering part;

4. and (4) conducting wires.

Detailed Description

The mechanical circulatory assist device implanted in the aorta of the present invention will be described in further detail with reference to the accompanying drawings and embodiments of the present invention.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.

It should be noted that the terms "first," "second," and the like in the description and claims of this application and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used is interchangeable under appropriate circumstances such that the embodiments of the application described herein are, for example, capable of operation in sequences other than those illustrated or otherwise described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.

Spatially relative terms, such as "above … …," "above … …," "above … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial relationship to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary term "above … …" can include both an orientation of "above … …" and "below … …". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

As shown in fig. 1, fig. 2, fig. 3, fig. 4, fig. 5, fig. 6 and fig. 7, the mechanical circulatory assist device implanted in the aorta comprises: the blood flow accelerating device comprises a power device 1 for providing a suction power source for blood flow, a driving device 2 for rotationally driving the blood to flow in an accelerating way and increasing the flow of the blood to important organs, and a fixing device 3 for fixing the whole auxiliary device in the descending aorta of a patient, wherein one end of a power output end (a preferred output shaft) of the power device 1 is connected with the driving device 2 to drive the driving device to accelerate the flow of the blood.

In order to ensure the position fixing of the power device 1 and the driving device 2 in the descending aorta blood vessel and the safety of a patient in the using process, the fixing device 3 is fixedly connected to the outer wall of the power device 1 and the outer wall of the driving device 2 (namely, the fixing device 3 is connected with the driving device 2 and the power device 1), or the fixing device 3 is fixedly connected to the outer wall of the power device 1 (not shown in the attached drawing), and as the driving device 2 and the power device 1 are in a connected state, the connection of the driving device 2 can be realized as long as the power device 1 with larger volume can be fixed, the position fixing of the whole device in the descending aorta is ensured, and the acceleration effect on blood is met.

Of course, for the purpose of anchoring inside the descending aorta, the anchoring device 3 is fixed to the inner wall of the descending aorta of the patient to be treated, so that the driving device 2 is fixed in position and can drive the blood flow. The aorta implanted mechanical circulation auxiliary device has a simple overall structure, and can be used for sending the whole device to the descending aorta position of a patient in an interventional operation mode, increasing the blood flow of blood flowing to each organ of the patient and meeting the blood supply of the organ; the operation risk is reduced, the application range is wide, and especially, the operation risk is high for patients who cannot be controlled by using medicines only.

In order to achieve a driving action on the blood, the driving device 2 comprises: the blood vessel separating device mainly comprises a driving impeller 21 for driving blood, a separating and blocking cylinder 22 for providing enough running space for the driving impeller 21 and ensuring the separation between the driving impeller and the blood vessel, and a connecting rod 23 for connecting the separating and blocking cylinder 22 and the power device 1. The power output end (which can be an output shaft) of the power device 1 is in driving connection with the driving impeller 21, a rotating shaft of the driving impeller 21 between the driving impeller and the driving impeller can be directly and integrally formed or fixedly connected with the output shaft, the size is reduced, the blood is ensured not to be polluted easily, and the use safety of a patient is further ensured. The tail end of the blocking cylinder 22 is fixedly connected with one end of a driving impeller 21 connected with the power device 1 through a connecting rod 23; the drive impeller 21 is provided inside the baffle cylinder 22.

Preferably, three connecting rods 23 are provided to ensure the connecting strength between the power device 1 and the blocking cylinder 22. And then guaranteed the clearance between the connecting rod 23 to make, drive impeller 21 suction blood in-process, can be more smooth flow out through the clearance between the connecting rod 23, realize the better effect that accelerates blood flow of auxiliary device.

Preferably, the connecting rod 23 is a net structure, and on the premise that sufficient blood flows out, the connecting rod 23 is directly formed by being integrally formed with the blocking barrel 22, and the net structure of the connecting rod 23 is directly formed by cutting. Further preferably, the connecting rod 23, the blocking cylinder 22 and the shell of the power device 1 are integrally formed, so that the sealing effect and the integrity of the whole device are ensured, and the use safety of a patient is further improved.

Preferably, the blade ends of the driving impeller 21 are all processed into a blunt structure, so as to reduce the damage to blood. And the two driving impellers 21 are arranged, so that the driving impellers 21 are large enough, blood can smoothly enter the action surface of the driving impellers 21, and the acceleration effect on the blood is ensured.

In order to achieve a strong fixation between the fixation device 3 and the descending aorta and to ensure a maximum degree of damage to the descending aorta. The fixing device 3 includes: a connecting part 31 which is connected with the end part of the driving device 2 and has a certain drainage function to a certain extent; a cylindrical fixing part 32 which is supported by friction with the inner wall of the descending aorta vessel and ensures that the inner wall of the descending aorta vessel has enough life activity clearance; the filter part 33 can filter all blood vessels passing through the auxiliary device and further ensure the use safety of the patient to the maximum extent, and the connecting part 31, the fixing part 32 and the filter part 33 are preferably integrally woven. The two ends of the connecting part 31 are fixedly connected with the fixing part 32 and the front end of the blocking cylinder 22 respectively, so that the fixing strength of the fixing part 32 to the whole power device 1 and the whole driving device 2 is ensured. The other end of the fixing part 32 is connected with the filter part 33; the other end of the filter portion 33 is connected to the power unit) away from the end of the drive impeller 21. Because all blood that passes through auxiliary device all will pass through filter house 33 to through the design to filter house 33 structure, guarantee filter house 33 to all blood filtration through, guarantee patient's safety in utilization.

In order to better drain the blood from the connecting portion 31, it is more favorable for the blood to pass through the driving impeller 21, and the blood supply to the organ is ensured through the acceleration of suction. The connecting portion 31 has an open structure, and has a minimum size at the position of the blocking barrel 22 and a maximum volume at the junction of the connecting portion 31 and the fixing portion 32, and the junction is located at the most upstream position of the whole auxiliary device close to the descending aorta blood vessel.

In order to ensure better filtering effect of the filtering part 33, and the filtered dirt can be collected to the most downstream position of the whole filtering part 33, the filtering part 33 is prevented from being blocked, and the service life of the whole filtering part 33 is ensured. The structure of the filter part 33 and the structure of the connecting part 31 are symmetrical.

In order to ensure the supporting strength of the fixing portion 32 and avoid the damage of the fixing device 3 to the inner wall of the descending aorta, the fixing portion 32 has a tubular structure (of course, all positions of the whole structure of the fixing device 3 are in a grid structure). The tubular structure can be supported with the inner wall of the descending aorta vessel, and the whole auxiliary device is fixed at the descending aorta position set by medical care personnel through enough supporting force.

The filter 33 may have a semicircular arc structure for the convenience of manufacturing.

Preferably, the entire fixing device 3 is woven of memory metal, with the density being the most sparse at the connecting portion 31 and the density being the greatest at the filter portion 33.

Further preferably, the memory metal is nitinol wire.

The whole auxiliary device is formed by connecting the patient in vitro, and then is sent to the descending aorta position of the patient through the axillary artery of the patient through the intervention equipment, so that the effect of accelerating the blood passing through the descending aorta is met. In order to ensure the energy supply of the power plant, the auxiliary device further comprises: a power supply device; the power output end of the power supply device is connected with the power input end of the power device.

In order to improve the integrity of the whole auxiliary device and avoid the inconvenience of the patient using the wire connection structure, the power supply device is arranged inside the shell of the power device 1.

In order to facilitate the replacement of the power supply device and charge the power supply device more smoothly by external equipment, the power supply device is arranged under the armpit skin of a patient to be treated (for facilitating intervention, particularly reducing the intervention distance and reducing the range of influencing blood vessels in the interventional operation process, the intervention in an armpit artery is selected), and the power supply output end of the power supply device is connected with the power supply input end of the power device 1 through a lead 4.

Preferably, the lead 4 passes through the cavity defined by the connector, anchor and filter portions, exits at the junction of the anchor and connector portions, and is routed directly along the axillary artery to the site of the patient's axilla, and is connected to a power supply device implanted beneath the surface of the patient's skin.

Preferably, the power supply device includes: the device comprises an internal antenna, a rectifying and smoothing circuit, a charging circuit and a battery; the internal antenna, the rectifying and smoothing circuit, the charging circuit and the battery are sequentially connected; the internal antenna may receive wireless signals generated by the external antenna. The signal received by the internal antenna is input to a rectifying and smoothing current and converted to a direct current. The charging circuit generates a current based on the power of the rectifying/smoothing circuit to charge the battery.

By means of the rechargeable battery device, replacement of the power supply device is reduced, and the service life of the auxiliary device is prolonged.

Preferably, the power unit 1 is a magnetic drive. The magnetic drive has better performance, and can seal inside the casing, guarantee rotatory output, and guarantee patient's safety in utilization.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention.

Claims

1. An intra-aortic implantable mechanical circulatory assist device, comprising: the device comprises a power device (1), a driving device (2) and a fixing device (3), wherein one end of the power device (1) is connected with the driving device (2);

the outer walls of the power device (1) and the driving device (2) are fixedly connected with the fixing device (3), or the outer wall of the power device (1) is fixedly connected with the fixing device (3);

the fixing device (3) is fixed on the inner wall of the descending aorta vessel of the patient to be treated, so that the driving device (2) drives the blood to flow.

2. The intra-aortic implantable mechanical circulatory assist device of claim 1, wherein the drive device (2) comprises: the power device comprises a driving impeller (21), a blocking cylinder (22) and a connecting rod (23), wherein the power output end of the power device (1) is in driving connection with the driving impeller (21); the tail end of the blocking cylinder (22) is fixedly connected with one end of a driving impeller (21) connected with the power device (1) through the connecting rod (23); the drive impeller (21) is provided inside the baffle cylinder (22).

3. The endoaortic implantable mechanical circulatory assist device of claim 2, wherein the fixation device (3) comprises: a connecting part (31), a fixing part (32) and a filtering part (33); two ends of the connecting part (31) are respectively fixedly connected with the fixing part (32) and the front end of the blocking barrel (22); the other end of the fixed part (32) is connected with the filtering part (33); the other end of the filtering part (33) is connected with one end of the power device (1) far away from the driving impeller (21).

4. The endoaortic implantable mechanical circulatory assist device of claim 3, wherein the connecting portion (31) is an open-ended structure;

the structure of the filtering part (33) and the structure of the connecting part (31) are symmetrical structures.

5. The endoaortic implantable mechanical circulatory assist device of claim 3 wherein the anchor portion (32) is generally cylindrical in configuration.

6. The mechanical circulatory assist apparatus according to claim 3, wherein said filter portion (33) is shaped like a half-circle arc.

7. The intra-aortic implantable mechanical circulatory assist device of claim 3, further comprising: a power supply device; and the power output end of the power supply device is connected with the power input end of the power device.

8. The endoaortic mechanical circulatory assist device of claim 7 wherein the power supply means is provided inside a housing of the power means (1).

9. The mechanical circulatory assist device of claim 7, wherein said power supply device is placed under the axillary skin of the patient to be treated, and the power supply output of said power supply device is connected to the power supply input of the power device (1) via a wire (4).

10. The mechanical circulatory assist device of any one of claims 1 to 9, wherein said power means (1) is a magnetic drive.