CN1108119A - Traditional Chinese medicinal extract containing Agkistrodon acutus - Google Patents

Abstract

The medicinal paste for external application consists of oldenlandia, root of angelica dahurica, mulberrystem etc., it has curative effect on vasculitis and phlebitis, and features easy application, notable effect and no side effect.

Description

Traditional Chinese medicinal extract containing Agkistrodon acutus

The present invention relates to a kind of Chinese medicinal ointment, particularly a kind of vasculitis and phlebitic external Traditional Chinese medicinal extract containing Agkistrodon acutus of curing mainly.

The vasculitis full name is a thromboangiitis obliterans, and the traditional Chinese medical science is called " gangrene of finger or toe ", is a kind of chronic peripheral angiopathy.Vasculitis mainly occurs in the middle small artery and the vein of human limb, mostly occurs at lower limb.Its clinical symptoms be suffer from that limb is sent out cold, numb, ischemia, pain, pulsation weakens or disappearance, skin purplish red, dark red or livid purple, often with the shallow table phlebitis of thrombosis, the burned black necrosis of severe patient acra, or the pus outflow of festering.Clinical commonly used drug is now: 1 oral or injection antiinflammatory class Western medicine, as oxytetracycline, streptomycin etc.; The multiple imperial antithrombotic pill of 2 oral Chinese medicines, TONGSAIMAI PIAN ..., or the injection snake venom etc.Anti-inflammatory drug has only played the effect to antiinflammatory, detumescence, alleviation and the inhibition PD of slight or the moderate state of an illness.Can produce certain side effect after the long-time medication.Chinese medicine oral and injection commonly used can play effects such as thromboembolism preventing, active, counteracting toxic substances, detumescence, pain relieving, and general slight and moderate vasculitis are had certain therapeutic effect.Above-mentioned clinical commonly used drug is poor to the severe vasculitis therapeutic effect of acra ulcer or necrosis, the radical cure effect that not reaching takes stopgap measures effects a permanent cure.Then adopt amputation to keep life to severe vasculitis in late period, also continue recurrence sometimes after the amputation, threat to life belongs to difficult and complicated illness.Therefore, developing little, the sick effect of side effect vasculitis specific drug remarkable, treating both the principal and secondary aspects of a disease at present is one of continuous special effect medicine of researching and developing of medical circle.

The purpose of this invention is to provide a kind of to vasculitis, phlebitis have significant curative effect, side effect Chinese medicine lotion for external use-Traditional Chinese medicinal extract containing Agkistrodon acutus extremely low, treating both the principal and secondary aspects of a disease.

The object of the present invention is achieved like this: Traditional Chinese medicinal extract containing Agkistrodon acutus is made up of Agkistrodon, the Radix Angelicae Dahuricae, Ramulus Mori, civilian strain, Olibanum, Myrrha, Flos Carthami, Sanguis Draxonis, Resina Ferulae, Sal Ammoniacus, Cinnabaris, Calomelas, Plumbum preparatium, first sheet, Radix Codonopsis, Radix Angelicae Sinensis, Semen Cuscutae, Herba Leonuri, Radix Et Rhizoma Rhei, the Cortex Eucommiae, Oleum sesami, its prescription following (percentage by weight):

Agkistrodon 1-9, Radix Angelicae Dahuricae 2-8, Ramulus Mori 4-12, civilian strain 4-11, Olibanum 3-10, Myrrha 2-11, Flos Carthami 2-10, Sanguis Draxonis 1-8, Resina Ferulae 2-7, Sal Ammoniacus 3-11, Cinnabaris 2-8, Calomelas 2-9, Plumbum preparatium 3-9, first sheet 2-10, Radix Codonopsis 3-12, Radix Angelicae Sinensis 2-11, Semen Cuscutae 2-10, Herba Leonuri 2-6, the 3-14 of Radix Et Rhizoma Rhei, Cortex Eucommiae 3-9, Oleum sesami 15-35.

Vasculitis is many because of deficiency of spleen-YANG and kidneyYANG, feel cold-damp or damp and hot invasion and attack again, and sluggish venation causes, or because of the heart, liver,kidney,spleen functional disorder, causes meridians and QI and blood dysfunction, and venation is blocked, blood stasis and row stagnates, and tunica intima produces pathological changes and forms.And Agkistrodon sweet in the mouth, salty in the present invention's prescription is warm in nature, poisonous; Radix Angelicae Dahuricae acrid in the mouth, warm in nature; Ramulus Mori bitter in the mouth, sweet, cold in nature, three flavor medicines are gone into liver, lung meridian, energy dispelling, collateral-activating, dampness, cold expelling heat, detoxifcation pain relieving; Literary composition strain, Olibanum bitter in the mouth, suffering, warm in nature; The Myrrha bitter in the mouth, property is flat, three flavor medicines are gone into the heart, Liver Channel, can circulation of qi promoting, invigorate blood circulation, promoting the circulation of blood, stimulate the menstrual flow, blood stasis dispelling, pain relieving; Flos Carthami, Radix Et Rhizoma Rhei's acrid in the mouth, warm in nature; First sheet salty in the mouth, cold nature; The Cinnabaris sweet in the mouth, cold nature, four Chinese medicine are gone into the heart, liver, spleen channel respectively, can stasis removing, invigorate blood circulation, stimulate the menstrual flow, clots absorbing, detoxifcation, detumescence and apocenosis, the arresting convulsion of calming the nerves; Sal Ammoniacus salty in the mouth, hardship, suffering, warm in nature, poisonous; Resina Ferulae bitter in the mouth, suffering, warm in nature; Sanguis Draxonis sweet in the mouth, salty, property is flat, three flavor medicines energy removing food stagnancy blood stasis dispelling, hard masses softening and resolving, expelling pus and promoting granulation; The Calomelas acrid in the mouth, cold in nature; The Plumbum preparatium acrid in the mouth, two flavor medicines energy parasite killing counteracting toxic substances, removing toxic substances and promoting tissue regeneration; Radix Angelicae Sinensis sweet in the mouth, suffering, warm in nature; Herba Leonuri acrid in the mouth, hardship, cold nature, two the flavor medicines go into the heart, liver, spleen channel, can enrich blood, promoting the circulation of blood, moisturize, blood stasis dispelling; Radix Codonopsis sweet in the mouth, little hardship, slightly warm in nature; Semen Cuscutae sweet in the mouth, suffering, slightly warm in nature; Cortex Eucommiae sweet in the mouth, little suffering, warm in nature, three flavor medicines are gone into spleen, lung, liver, kidney channel respectively, energy strongly invigorating primordial QI, warming the kidney to invigorate YANG, strong muscles and bones, tonifying liver; The Oleum sesami bitter in the mouth, cold in nature, the diarrhea of heat type fire that can disappear, nourishing kidney is moisturized.Above-mentioned each medicine compatibility supplements and complements each other, and attacks to mend and has both, so Traditional Chinese medicinal extract containing Agkistrodon acutus of the present invention has the outside of dispersing, tonifying QI to promote blood circulation, the meridian dredging, wind-damp dispelling, blood stasis dispelling blood, anti-inflammatory analgetic, the merit of the arresting convulsion of calming the nerves to the disease of vasculitis; The power that nourishing the liver spleen, warming the kidney to invigorate YANG, strengthening vital QI to eliminate pathogenic factors, hard masses softening and resolving, stasis removing, detumescence and apocenosis, treating the poisonous disease with poisonous drugs, removing toxic substances and promoting tissue regeneration, putrefaction removing and tissue regeneration promoting are more arranged meets the pharmacology of the traditional Chinese medical science, debates the rule that disease executing controlled.

Traditional Chinese medicinal extract containing Agkistrodon acutus clinical treatment vasculitis of the present invention, phlebitis 150 examples, wherein majority is the middle and advanced stage case.The trouble limb place pain of middle and advanced stage case is unusual, and illing skin is purplish red, dark red or livid purple, acra blood stasis, even the black purple or ulcer junk of acra, and weight person forms the fistula road, suppurates and drop down water, bone lesion.After using Traditional Chinese medicinal extract containing Agkistrodon acutus to treat a week, the affected part blood circulation improves rapidly, and pain obviously alleviates; Pus and exudate fall sharply after two to three weeks of treatment; Around the treatment remove the rotten and let fresh grow in the affected part, back, and long new granulation begins to close up; Promptly close up after the treatment moon is surplus and heal the smooth beniol of blood.General treatment can be fully recovered after two months.These middle and advanced stage cases all had the medical history of seeking medical advice and medicine in various degree, all passed through the treatment of present clinical therapy commonly used and Chinese and Western common drug, had only received general antiinflammatory, alleviation or the medical effect that suppresses.What wherein have reaches the more than ten years obstinate, or even vasculitis and phlebitic complication, and existing the cutting in finger of suffering from limb refers to a medical history, and continues to fester and stretch.Above-mentioned middle and advanced stage case except that minority extreme case beyond cure, is all proved effective after Traditional Chinese medicinal extract containing Agkistrodon acutus treatment, and effective percentage accounts for 92% of total case, obvious effective rate accounts for 84%, the avirulence reflection, and none recurrence, worsen amputation.During clinical application, according to affected part area size, weight, with ointment according to quantity Wen Huahou spread out in the sterilization Tobe on, be affixed on the affected part and get final product.

Therefore, we can say that Traditional Chinese medicinal extract containing Agkistrodon acutus is a kind of medicinal raw material wide material sources, is easy to get, medication is easy, easy to operate, and is evident in efficacy, has no side effect, and treatment time is short, cures mainly the Chinese medicinal ointment of vasculitis and phlebitic specially good effect external treating both the principal and secondary aspects of a disease.

In addition, multi-flavor medical instruments such as Sanguis Draxonis, Radix Angelicae Sinensis, civilian strain, the Cortex Eucommiae, Flos Carthami, Myrrha had the function of promoting blood flow to regulate menstruation, regulating qi to disperse stagnation, nourishing blood and preventing abortion during the present invention write out a prescription.So Traditional Chinese medicinal extract containing Agkistrodon acutus can also doublely be controlled habitual abortion, miscarriage is infertile, deficiency and coldness is infertile, sick in the menoxenia, amenorrhea, dysmenorrhea, gynecopathy such as pelvic inflammatory.During medication, only need ointment is affixed on according to case on the relevant acupoints of patient body, slowly absorb the lasting stimulation of the property of medicine and the property of medicine, reach the effect of inner disease outer treat the acupuncture point by skin.

Below be five specific embodiments of the present invention (percentage by weight):

Embodiment 1

Agkistrodon 9, the Radix Angelicae Dahuricae 2, Ramulus Mori 12, civilian strain 3, Olibanum 3, Myrrha 2, Flos Carthami 2, Sanguis Draxonis 1, Resina Ferulae 7, Sal Ammoniacus 3, Cinnabaris 8, Calomelas 2, Plumbum preparatium 3, first sheet 10, Radix Codonopsis 3, Radix Angelicae Sinensis 2, Semen Cuscutae 2, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 3, Oleum sesami 18.

Embodiment two

Agkistrodon 1, the Radix Angelicae Dahuricae 2, Ramulus Mori 4, civilian strain 3, Olibanum 10, Myrrha 2, Flos Carthami 2, Sanguis Draxonis 8, Resina Ferulae 2, Sal Ammoniacus 11, Cinnabaris 2, Calomelas 2, Plumbum preparatium 3, first sheet 2, Radix Codonopsis 12, Radix Angelicae Sinensis 2, Semen Cuscutae 2, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 9, Oleum sesami 16.

Embodiment three

Agkistrodon 1, the Radix Angelicae Dahuricae 8, Ramulus Mori 4, civilian strain 11, Olibanum 3, Myrrha 11, Flos Carthami 10, Sanguis Draxonis 1, Resina Ferulae 2, Sal Ammoniacus 3, Cinnabaris 2, Calomelas 9, Plumbum preparatium 3, first sheet 2, Radix Codonopsis 3, Radix Angelicae Sinensis 2, Semen Cuscutae 2, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 3, Oleum sesami 15.

Embodiment four

Agkistrodon 1, the Radix Angelicae Dahuricae 2, Ramulus Mori 4, civilian strain 3, Olibanum 3, Myrrha 2, Flos Carthami 2, Sanguis Draxonis 1, Resina Ferulae 2, Sal Ammoniacus 3, Cinnabaris 2, Calomelas 2, Plumbum preparatium 9, first sheet 2, Radix Codonopsis 3, Radix Angelicae Sinensis 11, Semen Cuscutae 10, Herba Leonuri 6, Radix Et Rhizoma Rhei 14, the Cortex Eucommiae 3, Oleum sesami 15.

Embodiment five

Agkistrodon 6, the Radix Angelicae Dahuricae 2, Ramulus Mori 4, civilian strain 3, Olibanum 3, Myrrha 2, Flos Carthami 5, Sanguis Draxonis 2, Resina Ferulae 2, Sal Ammoniacus 3, Cinnabaris 2, Calomelas 3, Plumbum preparatium 3, first sheet 3, Radix Codonopsis 7, Radix Angelicae Sinensis 4, Semen Cuscutae 3, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 3, Oleum sesami 35.

Claims (6)

1, a kind of treatment vasculitis and phlebitis and external Traditional Chinese medicinal extract containing Agkistrodon acutus, it is characterized in that forming its prescription following (percentage by weight) by Agkistrodon, the Radix Angelicae Dahuricae, Ramulus Mori, civilian strain, Olibanum, Myrrha, Flos Carthami, Sanguis Draxonis, Resina Ferulae, Sal Ammoniacus, Cinnabaris, Calomelas, Plumbum preparatium, first sheet, Radix Codonopsis, Radix Angelicae Sinensis, Semen Cuscutae, Herba Leonuri, Radix Et Rhizoma Rhei, the Cortex Eucommiae, Oleum sesami:

Agkistrodon 1-9, Radix Angelicae Dahuricae 2-8, Ramulus Mori 4-12, civilian strain 4-11, Olibanum 3-10, Myrrha 2-11, Flos Carthami 2-10, Sanguis Draxonis 1-8, Resina Ferulae 2-7, Sal Ammoniacus 3-11, Cinnabaris 2-8, Calomelas 2-9, Plumbum preparatium 3-9, first sheet 2-10, Radix Codonopsis 3-12, Radix Angelicae Sinensis 2-11, Semen Cuscutae 2-10, Herba Leonuri 2-6, the 3-14 of Radix Et Rhizoma Rhei, Cortex Eucommiae 3-9, Oleum sesami 15-35.

2, Traditional Chinese medicinal extract containing Agkistrodon acutus according to claim 1 is characterized in that described medical ointment prescription is (percentage by weight): Agkistrodon 9, the Radix Angelicae Dahuricae 2, Ramulus Mori 12, civilian strain 3, Olibanum 3, Myrrha 2, Flos Carthami 2, Sanguis Draxonis 1, Resina Ferulae 7, Sal Ammoniacus 3, Cinnabaris 8, Calomelas 2, Plumbum preparatium 3, first sheet 10, Radix Codonopsis 3, Radix Angelicae Sinensis 2, Semen Cuscutae 2, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 3, Oleum sesami 18.

3, Traditional Chinese medicinal extract containing Agkistrodon acutus according to claim 1 is characterized in that described medical ointment prescription is (percentage by weight): Agkistrodon 1, the Radix Angelicae Dahuricae 2, Ramulus Mori 4, civilian strain 3, Olibanum 10, Myrrha 2, Flos Carthami 2, Sanguis Draxonis 8, Resina Ferulae 2, Sal Ammoniacus 11, Cinnabaris 2, Calomelas 2, Plumbum preparatium 3, first sheet 2, Radix Codonopsis 12, Radix Angelicae Sinensis 2, Semen Cuscutae 2, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 9, Oleum sesami 16.

4, Traditional Chinese medicinal extract containing Agkistrodon acutus according to claim 1 is characterized in that described medical ointment prescription is (percentage by weight): Agkistrodon 1, the Radix Angelicae Dahuricae 8, Ramulus Mori 4, civilian strain 11, Olibanum 3, Myrrha 11, Flos Carthami 10, Sanguis Draxonis 1, Resina Ferulae 2, Sal Ammoniacus 3, Cinnabaris 2, Calomelas 9, Plumbum preparatium 3, first sheet 2, Radix Codonopsis 3, Radix Angelicae Sinensis 2, Semen Cuscutae 2, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 3, Oleum sesami 15.

5, Traditional Chinese medicinal extract containing Agkistrodon acutus according to claim 1 is characterized in that described medical ointment prescription is (percentage by weight): Agkistrodon 1, the Radix Angelicae Dahuricae 2, Ramulus Mori 4, civilian strain 3, Olibanum 3, Myrrha 2, Flos Carthami 2, Sanguis Draxonis 1, Resina Ferulae 2, Sal Ammoniacus 3, Cinnabaris 2, Calomelas 2, Plumbum preparatium 9, first sheet 2, Radix Codonopsis 3, Radix Angelicae Sinensis 11, Semen Cuscutae 10, Herba Leonuri 6, Radix Et Rhizoma Rhei 14, the Cortex Eucommiae 3, Oleum sesami 15.

6, Traditional Chinese medicinal extract containing Agkistrodon acutus according to claim 1 is characterized in that described medical ointment prescription is (percentage by weight): Agkistrodon 6, the Radix Angelicae Dahuricae 2, Ramulus Mori 4, civilian strain 3, Olibanum 3, Myrrha 2, Flos Carthami 5, Sanguis Draxonis 2, Resina Ferulae 2, Sal Ammoniacus 3, Cinnabaris 2, Calomelas 3, Plumbum preparatium 3, first sheet 3, Radix Codonopsis 7, Radix Angelicae Sinensis 4, Semen Cuscutae 3, Herba Leonuri 2, Radix Et Rhizoma Rhei 3, the Cortex Eucommiae 3, Oleum sesami 35.