CN110749553A - Method for improving demodulation effect of catheter polarization sensitive optical coherence tomography - Google Patents
Method for improving demodulation effect of catheter polarization sensitive optical coherence tomography Download PDFInfo
- Publication number
- CN110749553A CN110749553A CN201910954687.5A CN201910954687A CN110749553A CN 110749553 A CN110749553 A CN 110749553A CN 201910954687 A CN201910954687 A CN 201910954687A CN 110749553 A CN110749553 A CN 110749553A
- Authority
- CN
- China
- Prior art keywords
- catheter
- polarization
- coherence tomography
- optical coherence
- sensitive optical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/21—Polarisation-affecting properties
- G01N21/23—Bi-refringence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Analytical Chemistry (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Psychiatry (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Signal Processing (AREA)
- Chemical & Material Sciences (AREA)
- Artificial Intelligence (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Radiology & Medical Imaging (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Abstract
A method for improving the demodulation effect of polarization-sensitive optical coherence tomography of a catheter is characterized in that the outer surface of a catheter sheath is selected as a reference surface before polarization calculation, and the reference surface is not influenced by a sample to be detected; and selecting the position of the outer surface of the catheter sheath by adopting a data frame, wherein the point with the maximum amplitude intensity in each column of A-line data falling in the data frame is taken as a reference point. The invention can improve the polarization resolving speed.
Description
Technical Field
The invention relates to the field of catheter imaging covering cardiovascular and cerebrovascular systems and the like by catheter Optical Coherence Tomography (OCT), in particular to a method for improving the demodulation effect of the catheter Polarization-sensitive OCT (Polarization-sensitive OCT), namely the birefringence information of a demodulation sample in a PS-OCT image.
Background
The catheter OCT imaging technology is a blood vessel imaging method with the highest image resolution at present, particularly the catheter PS-OCT imaging technology, can solve the medical problem that the stability of atherosclerotic plaques is difficult to judge in vivo, in real time and rapidly, and can improve the prevention and treatment effect of atherosclerotic diseases. However, the existing OCT system has reached a level that may determine the property of the tissue plaque in terms of resolution, but is still insufficient in terms of tissue penetration ability, image sharpness, and accuracy of tissue plaque type determination, and using the PS-OCT technology, improving the performance of the related technology is a key direction for development of the OCT system, and is also a necessary way to solve the aforementioned key scientific problems.
In catheter OCT, catheter PS-OCT is an extension of catheter OCT technology, which provides a quantitative measure of tissue birefringence properties. The birefringence of light changes the polarization state of light and can be associated with proteins and biological macromolecules with oriented structures such as collagen, actin, and the like. The enhanced birefringence phenomenon of catheter PS-OCT is closely related to the existence of a large amount of thick collagen fibers or intimal smooth muscle cells, so that the high-resolution detection of catheter PS-OCT imaging can be applied to the enhanced plaque stability measurement. In addition, catheter PS-OCT systems have the potential to assess plaque collagen and differentiate normal intima, fibrous plaque, lipid plaque, and calcified plaque, among others.
In the catheter-based PS-OCT system, since the rotation of the catheter during imaging causes the birefringence information of the signal and the random birefringence information caused by the rotation of the catheter to be mixed together and difficult to distinguish, the reflected signal of a reference plane needs to be selected to compensate the random birefringence information introduced by the rotation of the catheter. The requirements for this reference plane are: has stable signal strength; the reflected signal carries random birefringence information introduced by catheter rotation; is easy to extract. The signal sources that satisfy these three requirements are mainly: the front surface of the catheter, the back surface of the catheter and the boundary of the tissues such as blood vessels. Since the boundary extraction of the vascular tissue depends on the imaging effect and the vascular tissue itself carries some birefringence information, interference is introduced.
Disclosure of Invention
The invention aims to provide a method for improving the demodulation effect of catheter polarization-sensitive Optical Coherence Tomography (OCT), aiming at the problem that the polarization resolution is seriously influenced by a plurality of reference surfaces in the conventional demodulation process of the catheter polarization-sensitive OCT
The technical scheme of the invention is as follows:
a method for improving the demodulation effect of polarization-sensitive optical coherence tomography of a catheter is characterized in that the outer surface of a catheter sheath is selected as a reference surface before polarization calculation, and the reference surface is not influenced by a sample to be detected; and selecting the position of the outer surface of the catheter sheath by adopting a data frame, wherein the point with the maximum amplitude intensity in each column of A-line data falling in the data frame is taken as a reference point.
The Fresnel reflection optical power of the reference surface is relatively stable, and the problem of tissue birefringence image error caused by unstable reflection optical power of biological tissues or sample surfaces can be effectively avoided.
The invention has the beneficial effects that:
the method can obviously improve the accuracy of the polarization calculation result and improve the analysis speed.
Drawings
FIG. 1 is a schematic representation of birefringence information extracted using the inner surface of a catheter as a reference plane.
FIG. 2 is a schematic representation of birefringence information extracted using the outer surface of a catheter as a reference plane.
Detailed Description
The invention is further described below with reference to the figures and examples.
As shown in fig. 2.
A method for improving demodulation effect of polarization-sensitive optical coherence tomography of a catheter is characterized in that the outer surface of a catheter sheath is selected as a reference surface before polarization resolving is carried out, and the reference surface is not influenced by a sample to be detected; and selecting the position of the outer surface of the catheter sheath by adopting a data frame, wherein the point with the maximum amplitude intensity in each column of A-line data falling in the data frame is taken as a reference point. The Fresnel reflection optical power of the reference surface is relatively stable, and the problem of tissue birefringence image error caused by unstable reflection optical power of biological tissues or sample surfaces can be effectively avoided.
Only the inner and outer surfaces of the catheter are generally considered as objects of study during the actual analysis process. Experiments show that the selection of the reference surface influences the result of polarization solution, as shown in fig. 1, it can be seen that the polarization contrast of the area selected in the box is reduced, and the result of polarization solution is misaligned.
As can be seen from FIG. 1, the selection of different reference planes and the polarization solution for tissue birefringence are different, which illustrates that the selection of the reference planes is important. The outer surface of the optical fiber conduit is selected as a reference surface because the optical power of Fresnel reflection of the optical fiber conduit is relatively stable, and the problem of tissue birefringence image error caused by unstable reflected optical power of a biological tissue or a sample surface can be effectively solved.
The parts not involved in the present invention are the same as or can be implemented using the prior art.
Claims (2)
1. A method for improving the demodulation effect of polarization-sensitive optical coherence tomography of a catheter is characterized in that the outer surface of a catheter sheath is selected as a reference surface before polarization calculation, and the reference surface is not influenced by a sample to be detected; and selecting the position of the outer surface of the catheter sheath by adopting a data frame, wherein the point with the maximum amplitude intensity in each column of A-line data falling in the data frame is taken as a reference point.
2. The method of claim 1, wherein the fresnel reflected light power of the outer surface is relatively stable, which effectively avoids the problem of tissue birefringence image errors caused by instability of reflected light power of the biological tissue or sample surface.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910954687.5A CN110749553A (en) | 2019-10-09 | 2019-10-09 | Method for improving demodulation effect of catheter polarization sensitive optical coherence tomography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910954687.5A CN110749553A (en) | 2019-10-09 | 2019-10-09 | Method for improving demodulation effect of catheter polarization sensitive optical coherence tomography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110749553A true CN110749553A (en) | 2020-02-04 |
Family
ID=69277791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910954687.5A Pending CN110749553A (en) | 2019-10-09 | 2019-10-09 | Method for improving demodulation effect of catheter polarization sensitive optical coherence tomography |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110749553A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113665150A (en) * | 2021-08-31 | 2021-11-19 | 广州永士达医疗科技有限责任公司 | Hose manufacturing method and probe hose |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130010303A1 (en) * | 2007-11-12 | 2013-01-10 | Lightlab Imaging, Inc. | Imaging Catheter With Integrated Reference Reflector |
| CN106361279A (en) * | 2016-08-30 | 2017-02-01 | 中国科学院上海光学精密机械研究所 | Full-investigation depth dispersion compensation method by optical coherence tomography system |
| CN109164048A (en) * | 2018-09-18 | 2019-01-08 | 天津大学 | The Polarization-Sensitive optical coherent chromatographic imaging of a kind of pair of conduit polarizes demodulation method |
-
2019
- 2019-10-09 CN CN201910954687.5A patent/CN110749553A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130010303A1 (en) * | 2007-11-12 | 2013-01-10 | Lightlab Imaging, Inc. | Imaging Catheter With Integrated Reference Reflector |
| CN106361279A (en) * | 2016-08-30 | 2017-02-01 | 中国科学院上海光学精密机械研究所 | Full-investigation depth dispersion compensation method by optical coherence tomography system |
| CN109164048A (en) * | 2018-09-18 | 2019-01-08 | 天津大学 | The Polarization-Sensitive optical coherent chromatographic imaging of a kind of pair of conduit polarizes demodulation method |
Non-Patent Citations (2)
| Title |
|---|
| DING ZHENYANG等: "Distributed refractive index sensing based on tapered fibers in optical frequency domain reflectometry", 《OPTICS EXPRESS》 * |
| TAO KUIYUAN等: "Catheter-Based Polarization Sensitive Optical Coherence Tomography Using Similar Mueller Matrix Method", 《IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113665150A (en) * | 2021-08-31 | 2021-11-19 | 广州永士达医疗科技有限责任公司 | Hose manufacturing method and probe hose |
| CN113665150B (en) * | 2021-08-31 | 2022-07-12 | 广州永士达医疗科技有限责任公司 | Hose manufacturing method and probe hose |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230414176A1 (en) | Intravascular Measurement And Data Collections Systems, Apparatus And Methods | |
| Regar et al. | Optical coherence tomography | |
| AU2008249176B2 (en) | Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties | |
| CN109164048B (en) | Polarization demodulation method for polarization-sensitive optical coherence tomography of catheter | |
| US9046339B2 (en) | Systems and methods for bidirectional functional optical coherence tomography | |
| US9089331B2 (en) | Characterizing ablation lesions using optical coherence tomography (OCT) | |
| Regar et al. | The diagnostic value of intracoronary optical coherence tomography | |
| Wilson et al. | Preliminary results from attenuation-slope mapping of plaque using intravascular ultrasound | |
| Schmitt et al. | Intravascular optical coherence tomography opens a window onto coronary artery disease | |
| EP3949836A2 (en) | Methods and systems for image synchronization | |
| Brezinski | Optical coherence tomography for identifying unstable coronary plaque | |
| Brugaletta et al. | Assessment of Plaque Composition by Intravascular Ultrasound and Near-Infrared Spectroscopy–From PROSPECT I to PROSPECT II– | |
| CN110749553A (en) | Method for improving demodulation effect of catheter polarization sensitive optical coherence tomography | |
| Regar et al. | Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies | |
| CN110742582A (en) | Binary image segmentation method for catheter polarization-sensitive optical coherence tomography | |
| Ban et al. | Advanced imaging modalities provide new insights into coronary artery calcification | |
| CN110731755A (en) | Polarization leveling method of catheter polarization-sensitive optical coherence tomography system | |
| CN110954481B (en) | Optimized average polarization demodulation method for catheter polarization sensitive optical coherence tomography | |
| Flamini et al. | Imaging arterial fibres using diffusion tensor imaging—Feasibility study and preliminary results | |
| CN111965114A (en) | Local birefringence demodulation method for catheter polarization-sensitive optical coherence tomography | |
| CN110742583A (en) | Spectral shaping method for polarization-sensitive optical coherence tomography demodulation of catheter | |
| CN113888478A (en) | Optimized depolarization method for intravascular catheter polarization-sensitive coherent tomography | |
| Gulizia et al. | Open questions in the assessment of liver fibrosis using real-time elastography | |
| Phipps et al. | Intravascular OCT imaging artifacts | |
| Regar et al. | Identifying stable coronary plaques with OCT technology |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200204 |
|
| RJ01 | Rejection of invention patent application after publication |