CN110713910A - Efficient separator for nucleic acid detection - Google Patents
Efficient separator for nucleic acid detection Download PDFInfo
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- CN110713910A CN110713910A CN201911127838.6A CN201911127838A CN110713910A CN 110713910 A CN110713910 A CN 110713910A CN 201911127838 A CN201911127838 A CN 201911127838A CN 110713910 A CN110713910 A CN 110713910A
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- rigid coupling
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Abstract
The invention discloses an efficient separating device for nucleic acid detection, which comprises a concave plate, wherein the bottom of the right side of the concave plate is fixedly connected with a transverse plate, the left side and the right side of the top of the concave plate are fixedly connected with vertical rods, the tops of the two vertical rods are fixedly connected with a straight plate, the outer walls of the two vertical rods are sleeved with springs, and the upper side and the lower side of each spring are fixedly connected with the bottom of the straight plate and the top of the concave plate respectively. Through slewing mechanism, supporting mechanism, the montant, the cooperation of straight board and spring, make whole device take place slight vibrations, reaction rate has been increased, the slow problem of reaction has been solved, work efficiency is improved, working time has been reduced, the trouble of having saved manual rocking has guaranteed that follow-up work is normal, contrast in the convenient work, the work degree of difficulty has been reduced, when the cooperation through fixed establishment and straight board makes a plurality of nucleic acid separation, make its job stabilization, the skew has been avoided, spray, usability has been improved, the function is comprehensive, and the convenience is promoted.
Description
Technical Field
The invention relates to the technical field of separation devices, in particular to a high-efficiency separation device for nucleic acid detection.
Background
Nucleic acids, which are the collective term for deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are a class of biopolymers that are essential to all known life forms, and consist of nucleotides, while the nucleotide monomers consist of a 5-carbon sugar, a phosphate group, and a nitrogenous base, and if the 5-carbon sugar is ribose, the resulting polymer is RNA.
Nucleic acid need separate when detecting, but the reaction of current separator for nucleic acid detection nucleic acid when using is slower, has reduced work efficiency, improves operating time, shakes uncontrollable dynamics with the hand, causes easily to spray, causes the waste, influences follow-up work to can't carry out a plurality of nucleic acid quickly separating simultaneously, inconvenient contrast has increased the work degree of difficulty, has reduced the usability, is not conform to modern's user demand
Disclosure of Invention
The invention aims to provide a high-efficiency separating device for nucleic acid detection, which aims to solve the problems that the existing separating device for nucleic acid detection has slow reaction of nucleic acid when in use, reduces the working efficiency, improves the working time, cannot control the force by shaking with hands, is easy to spray, wastes and influences the subsequent work in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a high-efficiency separating device for nucleic acid detection comprises a concave plate, wherein a transverse plate is fixedly connected to the bottom of the right side of the concave plate, vertical rods are fixedly connected to the left side and the right side of the top of the concave plate, straight plates are fixedly connected to the tops of the two vertical rods, springs are sleeved on the outer walls of the two vertical rods, the upper side and the lower side of each spring are fixedly connected with the bottom of each straight plate and the top of the concave plate respectively, and a rotating mechanism is mounted on the top of each transverse plate;
the rotating mechanism comprises a base, a motor, a round rod, a short plate and a short rod;
the bottom of base and the top looks rigid coupling of diaphragm, the top of base and the bottom looks rigid coupling of motor, the left side of motor and the right side looks rigid coupling of round bar, both ends rotate with the left and right sides of concave plate respectively about the outer wall of round bar and link to each other, the outer wall left and right sides of round bar all with the inner wall looks rigid coupling of short slab, two the inboard top of short slab respectively with the left and right sides looks rigid coupling of short bar.
Preferably, the bottom of the straight plate is provided with a supporting mechanism;
the supporting mechanism comprises a cylinder, a convex rod, a curved plate, a straight rod, a vertical rod and a sleeve plate;
the top of drum and the bottom looks rigid coupling of straight slab, the inner wall of drum and the outer wall slip joint of nose bar, the bottom of nose bar and the top looks rigid coupling of bent plate, the inner wall left and right sides of bent plate all rotates with the outer wall left and right sides of straight-bar and links to each other, the outer wall of straight-bar rotates with the top of montant and links to each other, the bottom of montant and the top looks rigid coupling of lagging, the inner wall of lagging rotates with the outer wall of quarter butt and links to each other.
Preferably, the cylinder and the protruding rod form a telescopic mechanism.
Preferably, the left side and the right side of the top of the straight plate are both provided with a fixing mechanism;
the fixing mechanism comprises a thin rod, a gear, a convex block, a long rod, a thin plate, a thick rod, a thick plate and a rubber block;
the outer wall of slender pole rotates with the top of straight board and links to each other, the top of slender pole and the bottom looks rigid coupling of gear, the left side of gear links to each other with the outer wall meshing of a plurality of lugs, and is a plurality of the left side of lug all with the right side looks rigid coupling of stock, the bottom of stock and the top looks rigid coupling of sheet metal, the top left side slip joint of sheet metal outer wall and straight board, the top of gear and the bottom looks rigid coupling of thick pole, the top of thick pole and the bottom left side looks rigid coupling of thick plate, the bottom right side of thick plate and the top looks rigid coupling of block rubber.
Preferably, the left sides of the convex blocks are equally distributed on the right side of the long rod and fixedly connected with the long rod.
Preferably, the top of the straight plate is attached with a test plate, and the top of the test plate is inserted with test tubes at equal intervals.
Compared with the prior art, the invention has the beneficial effects that: this high efficiency is separator for nucleic acid testing structure scientific and reasonable, convenience safe in utilization.
Through the cooperation of slewing mechanism, supporting mechanism, montant, straight board and spring, make whole device take place slight vibrations, increased reaction rate, solved the slower problem of reaction, improved work efficiency, reduced operating time, saved the trouble of manual rocking, avoided spraying, prevented extravagant, guaranteed that follow-up work is normal.
Through the cooperation of test board, test tube, slewing mechanism, supporting mechanism, montant, straight board and spring, realized a plurality of nucleic acid quickly separating, contrast in the convenient work has reduced the work degree of difficulty.
When the cooperation through fixed establishment and straight board makes a plurality of nucleic acid separation, make its job stabilization, avoided skew, spray, improved the usability, the function is comprehensive, the facilitate promotion.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view showing the connection structure of the round bar, the short plate and the short bar in FIG. 1;
FIG. 3 is a schematic view showing the connection structure of the cylinder, the protruding rod and the curved plate in FIG. 1;
FIG. 4 is a schematic view of the connection structure of the gear, the projection and the long rod in FIG. 1;
fig. 5 is a schematic view showing a connection relationship between the thick rod, the thick plate and the rubber block in fig. 1.
In the figure: 1. concave plate, 2, rotating mechanism, 201, base, 202, motor, 203, round bar, 204, short plate, 205, short bar, 3, supporting mechanism, 301, cylinder, 302, convex bar, 303, curved plate, 304, straight bar, 305, vertical bar, 306, sleeve plate, 4, fixing mechanism, 401, thin bar, 402, gear, 403, lug, 404, long bar, 405, thin plate, 406, thick bar, 407, thick plate, 408, rubber block, 5, transverse plate, 6, vertical bar, 7, straight plate, 8, spring, 9, test plate, 10, test tube.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: a high-efficiency separation device for nucleic acid detection, comprising a well plate 1, characterized in that: a transverse plate 5 is fixedly connected to the bottom of the right side of the concave plate 1, vertical rods 6 are fixedly connected to the left side and the right side of the top of the concave plate 1, straight plates 7 are fixedly connected to the tops of the two vertical rods 6, springs 8 are sleeved on the outer walls of the two vertical rods 6, the upper side and the lower side of each spring 8 are fixedly connected to the bottom of the straight plate 7 and the top of the concave plate 1 respectively, the straight plates 7 rebound through the springs 8 after moving downwards under stress, a rotating mechanism 2 is mounted on the top of the transverse plate 5, the rotating mechanism 2 comprises a base 201, a motor 202, a round rod 203, a short plate 204 and a short rod 205, the bottom of the base 201 is fixedly connected to the top of the transverse plate 5, the top of the base 201 is fixedly connected to the bottom of the motor 202, the motor 202 is 6W-400W in type, the left side of the motor 202 is fixedly connected to the right side of the round rod 203, the left end and the right end of the outer wall of the round rod 203, the left and right sides of the outer wall of the round rod 203 are fixedly connected with the inner walls of the short plates 204, and the tops of the inner sides of the two short plates 204 are fixedly connected with the left and right sides of the short rod 205 respectively.
The supporting mechanism 3 is installed at the bottom of the straight plate 7, the supporting mechanism 3 comprises a cylinder 301, a convex rod 302, a curved plate 303, a straight rod 304, a vertical rod 305 and a sleeve plate 306, the top of the cylinder 301 is fixedly connected with the bottom of the straight plate 7, the inner wall of the cylinder 301 is in sliding clamping connection with the outer wall of the convex rod 302, the convex rod 302 is stressed to move through the cylinder 301, the bottom of the convex rod 302 is fixedly connected with the top of the curved plate 303, the left side and the right side of the inner wall of the curved plate 303 are rotatably connected with the left side and the right side of the outer wall of the straight rod 304, the outer wall of the straight rod 304 is rotatably connected with the top of the vertical rod 305, the vertical rod 305 is stressed to rotate through the outer wall of the straight rod 304, the bottom of the sleeve plate 305 is fixedly connected with the top of the sleeve plate 306, the inner wall of the sleeve plate 306 is rotatably connected with the outer wall of the short rod 205, the sleeve plate, further realizing extension and contraction, the left side and the right side of the top of the straight plate 7 are respectively provided with a fixing mechanism 4, the fixing mechanisms 4 comprise a thin rod 401, a gear 402, a convex block 403, a long rod 404, a thin plate 405, a thick rod 406, a thick plate 407 and a rubber block 408, the outer wall of the thin rod 401 is rotatably connected with the top of the straight plate 7, the thin rod 401 is stressed to rotate through a bearing at the top of the straight plate 7, the top of the thin rod 401 is fixedly connected with the bottom of the gear 402, the left side of the gear 402 is meshed with the outer walls of the convex blocks 403, the left sides of the convex blocks 403 are fixedly connected with the right side of the long rod 404, the bottom of the long rod 404 is fixedly connected with the top of the thin plate 405, the outer wall of the thin plate 405 is slidably clamped with the left side of the top of the straight plate 7, the thin plate 405 is stressed to slide back and forth through a groove at the top of the straight plate 7, the top of the gear 402 is fixedly connected with the, the left sides of the bumps 403 are equally distributed on the right side of the long rod 404 and are fixedly connected with the gear 402, the inspection plate 9 is attached to the top of the straight plate 7, and the test tubes 10 are inserted into the top of the inspection plate 9 in equal distance.
In this example, when using the device, the test board 9 is now placed on the top of the straight board 7, then the test tube 10 is sequentially inserted into the inner wall of the test board 9, then the separation liquid is placed, then the long rod 404 is pulled outwards, and then the gear 402 is driven by the bump 403 to rotate on the inner wall of the bearing by the thin rod 401, the rotating gear 402 drives the thick plate 407 to rotate to the right side by the thick rod 406, and further the rubber block 408 abuts against the top of the test board 9, thereby fixing the test board 9 and the straight board 7, then the motor 202 is connected with the external power source, the motor 202 works to drive the round rod 203 to rotate by the bearings on the left and right sides of the concave board 1, the rotating round rod 203 drives the short board 204 to rotate, and further drives the sleeve board 306 to rotate by the short rod 205, the rotating sleeve board 306 drives the vertical rod 305 to deflect back and forth by the straight rod 304, and then drives the convex rod 302 to move downwards on the inner wall of the, thereby, the cylinder 301 drives the straight plate 7 to move downwards slightly, the moving straight plate 7 rebounds through the spring 8, and further the test tube 10 above is slightly vibrated, and the reaction of the separation solution and the nucleic acid is accelerated.
In the description of the present invention, it is to be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "one side", "top", "inner", "front", "center", "both ends", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "disposed," "connected," "secured," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A high-efficiency separation device for nucleic acid detection, comprising a well plate (1), characterized in that: a transverse plate (5) is fixedly connected to the bottom of the right side of the concave plate (1), vertical rods (6) are fixedly connected to the left side and the right side of the top of the concave plate (1), straight plates (7) are fixedly connected to the tops of the two vertical rods (6), springs (8) are sleeved on the outer walls of the two vertical rods (6), the upper side and the lower side of each spring (8) are fixedly connected to the bottom of each straight plate (7) and the top of the concave plate (1) respectively, and a rotating mechanism (2) is installed on the top of the transverse plate (5);
the rotating mechanism (2) comprises a base (201), a motor (202), a round rod (203), a short plate (204) and a short rod (205);
the bottom of base (201) and the top looks rigid coupling of diaphragm (5), the top of base (201) and the bottom rigid coupling of motor (202), the left side of motor (202) and the right side looks rigid coupling of round bar (203), both ends rotate with the left and right sides of concave plate (1) respectively about the outer wall of round bar (203) and link to each other, the outer wall left and right sides of round bar (203) all with the inner wall looks rigid coupling of short slab (204), two the inboard top of short slab (204) is respectively with the left and right sides looks rigid coupling of short slab (205).
2. The separation device for nucleic acid detection with high efficiency according to claim 1, wherein: the bottom of the straight plate (7) is provided with a supporting mechanism (3);
the supporting mechanism (3) comprises a cylinder (301), a convex rod (302), a curved plate (303), a straight rod (304), a vertical rod (305) and a sleeve plate (306);
the top of drum (301) and the bottom rigid coupling of straight board (7), the inner wall of drum (301) and the outer wall slip joint of nose bar (302), the bottom of nose bar (302) and the top rigid coupling of bent plate (303), the inner wall left and right sides of bent plate (303) all rotates with the outer wall left and right sides of straight-bar (304) and links to each other, the outer wall of straight-bar (304) rotates with the top of montant (305) and links to each other, the bottom of montant (305) and the top rigid coupling of lagging (306), the inner wall of lagging (306) rotates with the outer wall of quarter butt (205) and links to each other.
3. The separation device for nucleic acid detection with high efficiency according to claim 2, wherein: the cylinder (301) and the convex rod (302) form a telescopic mechanism.
4. The separation device for nucleic acid detection with high efficiency according to claim 1, wherein: the left side and the right side of the top of the straight plate (7) are both provided with a fixing mechanism (4);
the fixing mechanism (4) comprises a thin rod (401), a gear (402), a bump (403), a long rod (404), a thin plate (405), a thick rod (406), a thick plate (407) and a rubber block (408);
the outer wall of slender pole (401) rotates with the top of straight board (7) and links to each other, the top of slender pole (401) and the bottom rigid coupling of gear (402), the left side of gear (402) links to each other with the outer wall meshing of a plurality of lugs (403), and is a plurality of the left side of lug (403) all is with the right side rigid coupling of stock (404), the bottom of stock (404) and the top rigid coupling of sheet metal (405), the top left side slip joint of sheet metal (405) outer wall and straight board (7), the top of gear (402) and the bottom rigid coupling of thick pole (406), the top of thick pole (406) and the bottom left side rigid coupling of thick plate (407), the bottom right side of thick plate (407) and the top rigid coupling of rubber block (408).
5. The separation device for nucleic acid detection with high efficiency according to claim 4, wherein: the left sides of the convex blocks (403) are equally distributed on the right side of the long rod (404) and fixedly connected.
6. The separation device for nucleic acid detection with high efficiency according to claim 1, wherein: the top of the straight plate (7) is attached with a test plate (9), and the top of the test plate (9) is inserted with test tubes (10) in equal distance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911127838.6A CN110713910A (en) | 2019-11-18 | 2019-11-18 | Efficient separator for nucleic acid detection |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911127838.6A CN110713910A (en) | 2019-11-18 | 2019-11-18 | Efficient separator for nucleic acid detection |
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| CN110713910A true CN110713910A (en) | 2020-01-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201911127838.6A Pending CN110713910A (en) | 2019-11-18 | 2019-11-18 | Efficient separator for nucleic acid detection |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112063495A (en) * | 2020-10-20 | 2020-12-11 | 广州吉源生物科技有限公司 | Nucleic acid extraction device for nucleic acid extraction instrument |
| CN112268187A (en) * | 2020-11-20 | 2021-01-26 | 周英静 | Smart city that stability is strong uses cloud terminal |
-
2019
- 2019-11-18 CN CN201911127838.6A patent/CN110713910A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112063495A (en) * | 2020-10-20 | 2020-12-11 | 广州吉源生物科技有限公司 | Nucleic acid extraction device for nucleic acid extraction instrument |
| CN112063495B (en) * | 2020-10-20 | 2021-11-30 | 苏州康吉诊断试剂有限公司 | Nucleic acid extraction device for nucleic acid extraction instrument |
| CN112268187A (en) * | 2020-11-20 | 2021-01-26 | 周英静 | Smart city that stability is strong uses cloud terminal |
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Application publication date: 20200121 |