CN110711277A - Blood bilirubin decomposition device - Google Patents
Blood bilirubin decomposition device Download PDFInfo
- Publication number
- CN110711277A CN110711277A CN201910985570.3A CN201910985570A CN110711277A CN 110711277 A CN110711277 A CN 110711277A CN 201910985570 A CN201910985570 A CN 201910985570A CN 110711277 A CN110711277 A CN 110711277A
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- decomposition
- blood
- light source
- bilirubin
- container
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0621—Hyperbilirubinemia, jaundice treatment
Abstract
The invention discloses a blood bilirubin decomposition device, which provides the following technical scheme: including blood circulation pipeline, artificial heart lung machine and treatment bed, still including being used for decomposing the decomposition container of light source and light-permeable, the decomposition light source is set up to shine towards the decomposition container, is provided with input tube, output tube, spout, support and is used for protecting the guard shield of eyes on the treatment bed, and the input tube is connected with first entry, and the output tube is connected with first export, and sliding connection has the sliding closure on the support, and the guard shield slides and sets up on the spout, is provided with auxiliary light source on the sliding closure. When the device is used, the machine is preheated, the first inlet is connected to the artery, the first outlet is connected to the vein, the device is started, blood of a patient flows in the blood circulation pipeline under the action of the artificial heart-lung machine, and bilirubin in the blood is decomposed due to irradiation of the decomposition light after the blood enters the decomposition container, so that the content of bilirubin in the blood is effectively reduced.
Description
Technical Field
The invention relates to a blood bilirubin decomposition device, in particular to a blood bilirubin decomposition device.
Background
Jaundice is the most common clinical problem in the neonatal period, and is yellow-stained skin, sclera and other organs due to bilirubin accumulation in the body. Unconjugated bilirubin increase is the most common manifestation of neonatal jaundice, and serious patients can cause bilirubin encephalopathy, cause permanent damage to the nervous system, such as cerebral palsy, intelligence lag, epilepsy, impaired visual and auditory abilities and the like, and can seriously cause death.
Phototherapy, known as phototherapy, is a simple and effective method for reducing the amount of unbound bilirubin in the blood. The principle is that under the action of phototherapy, unconjugated bilirubin is photoisomerized to form water-soluble conformational isomers and structural isomers; the water soluble isomer has no neurotoxicity, and can be directly excreted out of the body via bile and urine without liver treatment. Phototherapy is mainly applied to skin superficial tissues, and the reduction of skin jaundice after phototherapy does not indicate that blood unbound bilirubin has fallen to a safe value; high concentration of unbound bilirubin in the blood can slowly permeate to the superficial skin and be removed from the body by phototherapy, gradual photoisomerization. Thus, a general degree of jaundice can be gradually reduced by phototherapy to a blood unbound bilirubin level. However, severe neonatal jaundice has high unconjugated bilirubin concentration in blood, and is likely to enter the brain, causing irreversible damage to the nervous system and causing bilirubin encephalopathy; phototherapy is not rapid enough to reduce unbound bilirubin in the blood for the treatment of severe jaundice. The severe jaundice infant needs to rapidly reduce the level of unconjugated bilirubin in blood, often needs to be treated by changing blood, the blood consumption of the treatment by changing blood is large, certain blood source waste is caused, certain time is needed for adjusting the blood source, and in addition, the change blood also has potential risk of infecting blood-borne diseases for patients.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a blood bilirubin decomposition device which can quickly reduce the content of bilirubin in blood.
In order to achieve the purpose, the invention provides the following technical scheme: blood bilirubin decomposition device, including the blood circulation pipeline, artificial heart lung machine and treatment bed, artificial heart lung machine connects on the blood circulation pipeline, be provided with first entry and first export on the blood circulation pipeline, still including being used for decomposing light source and light-permeable's decomposition container, be provided with second entry and second export on the decomposition container, second entry and second exit linkage are on the blood circulation pipeline, the decomposition light source is set up to shine towards the decomposition container, be provided with the input tube on the treatment bed, the output tube, the spout, support and the guard shield that is used for protecting eyes, the input tube is connected with first entry, the output tube is connected with first export, sliding connection has the sliding closure on the support, the guard shield slides and sets up on the spout, be provided with auxiliary light source on the sliding closure.
As a further improvement of the invention, a reflecting plate for reflecting light to irradiate the decomposition container is arranged on one side of the decomposition container, which is back to the decomposition light source, and the reflecting plate is arc-shaped, and the surface of the reflecting plate, which faces the decomposition light source, is a mirror surface.
As a further improvement of the invention, the decomposition container is a flat cavity, a guide cavity is arranged in the decomposition container, the guide cavity is in a continuous U shape, and the thickness direction of the decomposition container is the same as the irradiation direction of the decomposition light source.
As a further improvement of the invention, a plurality of decomposition light sources are arranged, surround the decomposition container and are all arranged to irradiate towards the decomposition container.
As a further improvement of the invention, the decomposition container is cylindrical, an annular decomposition cavity is arranged in the decomposition container, and the decomposition light source is arranged at the center of the decomposition container.
As a further improvement of the invention, the decomposition container is also provided with a second light source for emitting light rays for decomposing the blood bilirubin, the second light source is annular, and the second light source is sleeved on the decomposition container and is arranged to irradiate towards the decomposition container.
As a further improvement of the invention, a bilirubin detector for detecting the bilirubin concentration is arranged in the blood circulation circuit near the first outlet.
As a further improvement of the invention, the blood circulation pipeline is arranged in the heat insulation box, the heat insulation box comprises a box body and a constant temperature device, the box body is made of heat insulation transparent materials, the constant temperature device is provided with a constant temperature water pipe, and the constant temperature water pipe is sleeved on the blood circulation pipeline and is arranged close to the first outlet.
As a further improvement of the invention, the treatment bed is also provided with a placing frame for placing the sliding cover.
When the device is used, the machine is preheated, the first inlet is connected to the artery, the first outlet is connected to the vein, the device is started, blood of a patient flows in the blood circulation pipeline under the action of the artificial heart-lung machine, and bilirubin in the blood is decomposed due to irradiation of the decomposition light after the blood enters the decomposition container, so that the content of bilirubin in the blood is effectively reduced. The artificial heart-lung machine can effectively control various factors in blood, thereby avoiding the damage of the blood external circulation to human body. By adopting the mode, the optical fiber directly irradiates blood without separating tissues such as human skin, and the efficiency of decomposing bilirubin is high. And the blood circulation mode adopts the blood of the patient, reduces the consumption of blood resources and can avoid the risk of allogenic blood transfusion. The treatment bed is convenient for the patient to lie down and is beneficial to treatment. The input tube and the output tube are convenient to be connected with the blood bilirubin decomposition device to establish extracorporeal blood circulation. The slip cover is favorable for preventing bacterial infection, the ventilation holes are convenient for air circulation, breathing disorder is avoided, the auxiliary light source can carry out phototherapy, and the treatment effect is enhanced. The guard shield is avoided shining eyes at the phototherapy, avoids being injured, and the cooperation of sliding of guard shield and spout, the patient of being convenient for lies and crouches after on the treatment bed, removes the head with the guard shield again and protects.
Drawings
FIG. 1 is an overall block diagram of the present invention;
FIG. 2 is a schematic structural view of a flat decomposition vessel;
FIG. 3 is a side schematic view of a flattened decomposition vessel;
FIG. 4 is a schematic view of a cylindrical decomposition vessel;
FIG. 5 is a schematic view of a decomposition light source illuminating a decomposition vessel circumferentially;
fig. 6 is a schematic view of the treatment couch.
Detailed Description
The invention will be further described in detail with reference to the following examples, which are given in the accompanying drawings.
Referring to fig. 1 to 6, the blood bilirubin decomposition device of the present embodiment includes a blood circulation line 1, a heart-lung machine 2 and a treatment bed 6, the heart-lung machine 2 is connected to the blood circulation line 1, the blood circulation line 1 is provided with a first inlet 11 and a first outlet 12, and the blood bilirubin decomposition device is characterized in that: the treatment bed is characterized by further comprising a decomposition container 4 used for decomposing the light source 3 and light transmission, a second inlet 41 and a second outlet 42 are arranged on the decomposition container 4, the second inlet 41 and the second outlet 42 are connected to the blood circulation pipeline 1, the decomposition light source 3 is set to irradiate towards the decomposition container 4, an input pipe 61, an output pipe 62, a sliding groove 63, a support 65 and a shield 64 used for protecting eyes are arranged on the treatment bed 6, the input pipe 61 is connected with the first inlet 11, the output pipe 62 is connected with the first outlet 12, a sliding cover 651 is connected onto the support 65 in a sliding mode, the shield 64 is arranged on the sliding groove 63 in a sliding mode, and an auxiliary light source 652 is arranged on the sliding cover 63.
Through the scheme, when the device is used, the machine is preheated, the first inlet 11 is connected into an artery, the first outlet 12 is connected into a vein, the device is started, blood of a patient flows in the blood circulation pipeline 1 under the action of the artificial heart-lung machine 2, and after the blood enters the decomposition container 4, bilirubin in the blood is decomposed due to irradiation of decomposition light, so that the content of bilirubin in the blood is effectively reduced. The artificial heart-lung machine 2 can effectively control various factors in blood, thereby avoiding the damage of the blood external circulation to human body. By adopting the mode, the optical fiber directly irradiates blood without separating tissues such as human skin, and the efficiency of decomposing bilirubin is high. And the blood circulation mode adopts the blood of the patient, reduces the consumption of blood resources and can avoid the risk of allogenic blood transfusion. The treatment bed 6 is convenient for the patient to lie, and is beneficial to treatment. The inlet tube 61 and the outlet tube 62 are convenient for connecting with a blood bilirubin decomposition device to establish extracorporeal blood circulation. The sliding cover 651 is beneficial to preventing bacterial infection, the ventilation holes 631 facilitate air circulation to avoid breathing difficulty, and the auxiliary light source 632 can be used for phototherapy to enhance the treatment effect. The guard shield 64 avoids shining eyes at the phototherapy, avoids being injured, and guard shield 64 and spout 63 sliding fit are convenient for the patient to lie after on treatment bed 6, remove guard shield 64 to the head again and protect.
As a modified specific embodiment, a reflecting plate 31 for reflecting light to irradiate the decomposition container 4 is arranged on the side of the decomposition container 4 opposite to the decomposition light source 3, the reflecting plate 31 is arc-shaped, and the surface of the reflecting plate 31 facing the decomposition light source 3 is a mirror surface.
With the above arrangement, the reflecting plate 31 reflects the decomposition light from the decomposition light source 3, and enhances the intensity of the light irradiated to the decomposition light source 4, thereby accelerating the decomposition of bilirubin in blood and reducing the content of bilirubin in blood. The curved configuration facilitates the concentrated irradiation of the reflected decomposition light onto the decomposition vessel 4. The mirror surface has good reflection effect.
As a modified specific implementation mode, the decomposition container 4 is a flat cavity, a guide cavity 44 is arranged in the decomposition container 4, the guide cavity 44 is in a continuous U shape, and the thickness direction of the decomposition container 4 is the same as the irradiation direction of the decomposition light source 3.
Through the scheme, the continuous U-shaped blood collecting chamber is suitable for being arranged in the flat cavity, the illuminated area of unit blood is increased, the blood volume required by extracorporeal circulation is reduced, and the injury of the extracorporeal circulation to a human body is reduced. The blood circulates in the guide cavity 44, and the continuous U-shaped structure is favorable for prolonging the stroke of the blood, so that the bilirubin in the blood is fully irradiated by light, and the content of the bilirubin in the blood is reduced as much as possible. The area of the plane of the decomposition container 4 irradiated with the decomposition light from the decomposition light source 3 is large, so that the irradiation is more sufficient.
As a modified embodiment, the decomposition light source 3 is provided in a plurality, and the plurality of decomposition light sources 3 surround the decomposition container 4 and are all arranged to irradiate towards the decomposition container 4.
Through the scheme, a plurality of decomposition light sources 3 are irradiated around to form a shadowless environment, and irradiated decomposition light rays enable blood in the decomposition container 4 to be fully irradiated.
As a modified specific embodiment, the decomposition container 4 is cylindrical, the decomposition chamber 43 having a ring shape is provided in the decomposition container 4, and the decomposition light source 3 is provided at the center of the decomposition container 4.
Through the scheme, the decomposing container is set to be cylindrical, so that the area of unit blood receiving illumination is increased, the blood volume required by extracorporeal circulation is reduced, and the injury of the extracorporeal circulation to a human body is reduced.
As a modified embodiment, the decomposition container 4 is further provided with a second light source 32 for emitting light for decomposing blood bilirubin, the second light source 32 is annular, and the second light source 32 is fitted over the decomposition container 4 and is disposed to irradiate toward the decomposition container 4.
Through above-mentioned scheme, the loop configuration is favorable to, increases the area that unit blood received the illumination. And is matched with the decomposition light source 3, which is beneficial to enhancing the light intensity irradiated on the decomposition light source 4, accelerating the decomposition of the bilirubin in blood and reducing the content of the bilirubin in blood.
As a modified embodiment, a bilirubin detector is provided in the blood circulation circuit 1 near the first outlet 12.
By adopting the scheme, the bilirubin detector detects the bilirubin content of the treated blood, and when the bilirubin content is too high, the bilirubin can be decomposed in an accelerated manner by slowing down the flow speed or enhancing the illumination intensity; when the bilirubin content is too low, bilirubin decomposition can be slowed down by increasing the flow rate or by reducing the intensity of light. Through the steps, the content of bilirubin in blood can be ensured to be in a normal range, and overhigh or overlow bilirubin is avoided.
As an improved specific embodiment, the blood circulation device further comprises an insulation box 5, the blood circulation pipeline 1 is arranged in the insulation box 5, the insulation box 5 comprises a box body 51 and a constant temperature device 52, the box body 51 is made of insulation transparent materials, a constant temperature water pipe 53 is arranged on the constant temperature device 52, and the constant temperature water pipe 53 is sleeved on the blood circulation pipeline 1 and is arranged at a position close to the first outlet 12.
Through above-mentioned scheme, through the setting of insulation can 5, can avoid the blood temperature of reinjection too high or low excessively, harm the human body. The thermostatic device 52 keeps the temperature of the thermostatic water pipe 53 at a proper temperature, and the thermostatic water pipe 53 keeps the blood on the blood circulation pipeline 1 near the first outlet 12 at a proper temperature to maintain the activity of the blood so as to be input into the human body again and reduce the harm to the human body.
As a modified embodiment, the treatment couch 6 is further provided with a placing frame 66 for placing the sliding cover 63.
Through the scheme, the sliding cover 63 is placed on the placing frame 66, the sliding cover 63 is protected and supported, and the sliding cover 63 is prevented from being damaged.
The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above-mentioned embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.
Claims (9)
1. Blood bilirubin decomposition device, including blood circulation pipeline (1), artificial heart lung machine (2) and treatment bed (6), artificial heart lung machine (2) are connected on blood circulation pipeline (1), be provided with first entry (11) and first export (12) on blood circulation pipeline (1), its characterized in that: also comprises a decomposition light source (3) and a light-permeable decomposition container (4), wherein a second inlet (41) and a second outlet (42) are arranged on the decomposition container (4), the second inlet (41) and the second outlet (42) are connected to the blood circulation line (1), the decomposition light source (3) is arranged to irradiate towards the decomposition container (4), the treatment bed (6) is provided with an input pipe (61), an output pipe (62), a chute (63), a bracket (65) and a shield (64) for protecting eyes, the inlet pipe (61) is connected to the first inlet (11), the outlet pipe (62) is connected to the first outlet (12), the light source device is characterized in that a sliding cover (651) is connected to the support (65) in a sliding mode, the protective cover (64) is arranged on the sliding groove (63) in a sliding mode, and an auxiliary light source (652) is arranged on the sliding cover (63).
2. A blood bilirubin decomposition device according to claim 1 wherein: one side of the decomposition container (4) back to the decomposition light source (3) is provided with a reflecting plate (31) used for reflecting light rays to irradiate the decomposition container (4), the reflecting plate (31) is arc-shaped, and the surface of the reflecting plate (31) facing the decomposition light source (3) is a mirror surface.
3. A blood bilirubin decomposition device according to claim 2 wherein: the decomposition container (4) is a flat cavity, a guide cavity (44) is arranged in the decomposition container (4), the guide cavity (44) is in a continuous U shape, and the thickness direction of the decomposition container (4) is the same as the irradiation direction of the decomposition light source (3).
4. A blood bilirubin decomposition device according to claim 1 wherein: the decomposition light source (3) is provided with a plurality of decomposition light sources (3) surrounding the decomposition container (4) and all arranged to irradiate towards the decomposition container (4).
5. A blood bilirubin decomposition device according to claim 1 wherein: the decomposition container (4) is cylindrical, an annular decomposition cavity (43) is arranged in the decomposition container (4), and the decomposition light source (3) is arranged at the center of the decomposition container (4).
6. A blood bilirubin decomposition device according to claim 5 wherein: the decomposition container (4) is further provided with a second light source (32) used for emitting light for decomposing blood bilirubin, the second light source (32) is annular, and the second light source (32) is sleeved on the decomposition container (4) and is set to irradiate towards the decomposition container (4).
7. A blood bilirubin decomposition device according to claim 1 wherein: a bilirubin detector for detecting bilirubin concentration is arranged at a position, close to the first outlet (12), of the blood circulation pipeline (1).
8. A blood bilirubin decomposition device according to claim 1 wherein: still include insulation can (5), blood circulation pipeline (1) sets up in insulation can (5), insulation can (5) are including box (51) and constant temperature equipment (52), box (51) adopt heat preservation transparent material, be provided with constant temperature water pipe (53) on constant temperature equipment (52), constant temperature water pipe (53) cover is established on blood circulation pipeline (1) to the setting is being close to first export (12) department.
9. A blood bilirubin decomposition device according to claim 1 wherein: the treatment bed (6) is also provided with a placing frame (66) for placing the sliding cover (63).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910985570.3A CN110711277A (en) | 2019-10-17 | 2019-10-17 | Blood bilirubin decomposition device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910985570.3A CN110711277A (en) | 2019-10-17 | 2019-10-17 | Blood bilirubin decomposition device |
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| Publication Number | Publication Date |
|---|---|
| CN110711277A true CN110711277A (en) | 2020-01-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910985570.3A Pending CN110711277A (en) | 2019-10-17 | 2019-10-17 | Blood bilirubin decomposition device |
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| CN (1) | CN110711277A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1572332A (en) * | 2003-05-30 | 2005-02-02 | 富瑞森尼尔斯医护德国有限公司 | Device for extracorporal irradiation of a liquid containing bilirubin, and method therefor |
| US20090131771A1 (en) * | 2005-07-01 | 2009-05-21 | Yoshimasa Takeda | Apparatus For Denaturating Bilirubin And Bilirubin Dialyzer |
| US20130345614A1 (en) * | 2012-06-22 | 2013-12-26 | Viraj P. Mane | Device for extracorporeal photo-isomerization for hyperbilirubinemia, and method thereof |
| CN104548233A (en) * | 2013-10-23 | 2015-04-29 | 国医华科（深圳）医疗科技发展有限公司 | Blood irradiator |
| CN206391261U (en) * | 2016-09-20 | 2017-08-11 | 新乡医学院第三附属医院 | A kind of blood purification medical treatment equipment |
| CN206499779U (en) * | 2016-10-31 | 2017-09-19 | 重庆尚游婴儿游泳馆有限责任公司 | Infant Bath Room blue-ray light bed |
| CN107929840A (en) * | 2017-11-09 | 2018-04-20 | 广州星顿医疗科技有限公司 | A kind of external red light irradiation therapeutic equipment |
-
2019
- 2019-10-17 CN CN201910985570.3A patent/CN110711277A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1572332A (en) * | 2003-05-30 | 2005-02-02 | 富瑞森尼尔斯医护德国有限公司 | Device for extracorporal irradiation of a liquid containing bilirubin, and method therefor |
| US20090131771A1 (en) * | 2005-07-01 | 2009-05-21 | Yoshimasa Takeda | Apparatus For Denaturating Bilirubin And Bilirubin Dialyzer |
| US20130345614A1 (en) * | 2012-06-22 | 2013-12-26 | Viraj P. Mane | Device for extracorporeal photo-isomerization for hyperbilirubinemia, and method thereof |
| CN104548233A (en) * | 2013-10-23 | 2015-04-29 | 国医华科（深圳）医疗科技发展有限公司 | Blood irradiator |
| CN206391261U (en) * | 2016-09-20 | 2017-08-11 | 新乡医学院第三附属医院 | A kind of blood purification medical treatment equipment |
| CN206499779U (en) * | 2016-10-31 | 2017-09-19 | 重庆尚游婴儿游泳馆有限责任公司 | Infant Bath Room blue-ray light bed |
| CN107929840A (en) * | 2017-11-09 | 2018-04-20 | 广州星顿医疗科技有限公司 | A kind of external red light irradiation therapeutic equipment |
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Application publication date: 20200121 |