CN110710994A

CN110710994A - Tissue sampler

Info

Publication number: CN110710994A
Application number: CN201911097618.3A
Authority: CN
Inventors: 杨杨
Original assignee: Jiashan Hongyu Technology Consulting Co Ltd
Current assignee: ZHEJIANG TANZHEN BIOTECHNOLOGY Co.,Ltd.
Priority date: 2019-11-11
Filing date: 2019-11-11
Publication date: 2020-01-21

Abstract

A tissue sampler comprises a sampling part, wherein the sampling part comprises a sampling sleeve, a sampling core rod and a sampling notch. The sampling cannula has a longitudinal axis and a receiving cavity disposed along the longitudinal axis. The sampling core rod comprises a body, a far end and a near end, wherein the body is arranged in the accommodating cavity and is in clearance fit with the accommodating cavity, the near end is operated, the body reciprocates in the accommodating cavity along the same direction of the longitudinal axis, and the far end is positioned outside an opening at one end of the accommodating cavity and is used for puncturing tissues. The sampling incision is arranged on the side wall of the sampling sleeve, communicated with the accommodating cavity and used for shearing tissues. The tissue sampler provided by the invention can carry out directional biopsy sampling on target tissues, does not need to repeatedly stab peripheral tissues of the sampled target tissues to cause damage, and shortens the healing time of tissues after biopsy.

Description

Tissue sampler

Technical Field

The invention relates to a medical instrument, in particular to an instrument for sampling tissues, which is beneficial to acquiring target tissues in a biopsy operation and reducing the damage area of peripheral tissues.

Background

"biopsy" refers to a technique for taking a lesion tissue from a patient by cutting, clamping, or puncturing, and performing pathological examination, as needed for diagnosis and treatment. It is the most important part of the diagnosis pathology, and it can make clear histopathological diagnosis for most of the examined cases, and it is used as the final diagnosis in clinic.

Biopsies are classified in a sampling fashion, such as: open biopsy (surgery), endoscopic biopsy (biopsy forceps) and percutaneous needle biopsy (biopsy needle); classified by sampling site, such as: soft tissue biopsy and bone biopsy; classified by the examination sample, such as: cytological biopsy and histological biopsy.

Patent CN201480065733.1 discloses a biopsy trocar for performing a safe, reliable and quick bone marrow biopsy procedure. It comprises a biopsy needle with a cannula and a spindle with a shaft adapted to slide in the biopsy needle. The cannula has at least one internal rib at its distal end forming a helical portion on the internal wall of the cannula, the shaft having a helical groove capable of mating with the internal rib, the internal rib being adapted to retain a bone marrow sample in the needle.

Patent CN201510458019.5 discloses a replaceable core biopsy needle providing a specific cutting slot defined on one side of the distal portion of the needle. The side-cutting slot is configured to collect a full core tissue sample and to leave the full core intact. The biopsy needle configuration enables maximizing tissue sample acquisition and further ensures cohesion of the collected sampled tissue.

The biopsy needle is clinically used, and soft tissue cutting and acquisition are realized under the shearing action generated by relative movement between a sampling mandrel and a sleeve in the sampling process. This approach requires repeated puncture of the tissue and does not allow accurate sampling of the locally diseased tissue.

Disclosure of Invention

One object of the present invention is to provide a tissue sampler, which is an instrument for sampling tissue, and is beneficial to obtaining target tissue in biopsy operation and reducing the damage area of peripheral tissue.

It is another object of the present invention to provide a tissue sampler, an apparatus for sampling tissue, which increases the amount of target tissue obtained during a biopsy procedure while reducing the area of damage to surrounding tissue.

It is a further object of the present invention to provide a tissue sampler that is an instrument for sampling tissue that reduces the time required for a biopsy procedure.

It is a further object of the present invention to provide a tissue sampler for use with an instrument for sampling tissue that reduces the time of a biopsy procedure while increasing the amount of tissue sampled from the biopsy.

The invention provides a tissue sampler, which comprises a sampling part, wherein the sampling part comprises

A sampling cannula having a longitudinal axis and a receiving cavity disposed along the longitudinal axis;

the sampling core rod comprises a body, a far end and a near end, wherein the body is arranged in the accommodating cavity and is in clearance fit with the accommodating cavity, the near end is operated, the body moves in the accommodating cavity in a reciprocating manner along the same direction of the longitudinal axis, and the far end is positioned outside an opening at one end of the accommodating cavity and is used for penetrating into tissues;

and the sampling incision is arranged on the side wall of the sampling sleeve, is communicated with the accommodating cavity and is used for shearing tissues.

In another embodiment of the tissue sampler, a sampling groove is formed in the sampling core rod. When the obtained tissue enters the sampling incision, the tissue is gathered in the sampling groove.

In another embodiment of the tissue sampler, at least 2 sampling cuts, in particular 2 to 6 sampling cuts, are provided in the side wall of the sampling cannula, such as: 2, 3, 4, 5, 6, etc. These sampling cuts are evenly distributed around the sidewall of the sampling cannula.

The tissue sampler of the present invention, the sampling incision comprises:

the collecting opening is arranged on the side wall of the sampling sleeve and is communicated with the accommodating cavity;

the cutting part, it links to each other with sampling sleeve's lateral wall, including cutting end, collection arc and cutting arc, cutting end will gather the arc and separate with cutting arc, cutting end is used for implementing fixedly to the tissue to with gather open-ended edge cooperation and implement the shearing to the tissue, gather the arc and guide the fixed tissue of cutting end, get into and gather the opening, be convenient for gather open-ended edge and cutting end and implement the shearing to the tissue, cutting arc is used for assisting cutting end to implement the shearing.

Another sampling slit embodiment, the cutting arc is curved toward the collection opening and includes a first arc, a second arc, and a third arc. The both ends of second arc are connected with first arc and second arc respectively, and cutting tip is close to first arc, and third arc one end sets up on sampling sleeve's lateral wall.

In another embodiment of the sampling incision, the radius of curvature of the first arc portion is 0.50mm +/-0.02 mm, the radius of curvature of the second arc portion is 3.50mm +/-0.02 mm, the radius of curvature of the third arc portion is 6.80mm +/-0.02 mm, and the three arc portions are mutually matched to sequentially fix tissues, guide the collected tissues to enter the collection opening and prevent the tissues entering the collection opening from sliding outwards.

In another embodiment of the sampling slit, the ratio of the radius of curvature of the cutting arc to the radius of curvature of the sidewall of the sampling cannula is 1.45 to 1. When the ratio of the radius of curvature of the cutting arc to the radius of curvature of the sidewall of the sampling cannula is 1, it is understood that the cutting arc is a portion of the sidewall of the sampling cannula.

The technical scheme of the invention has the following beneficial effects:

the tissue sampler provided by the invention can carry out directional biopsy sampling on the target tissue, does not need to repeatedly stab and damage the peripheral tissue of the sampled target tissue, and shortens the tissue healing time after the biopsy.

The tissue sampler provided by the invention has the advantages that the sampling sleeve rotates around the longitudinal axis of the sampling sleeve relative to the body, so that the sampling incision performs biopsy sampling on a target tissue in a shearing sampling mode, the biopsy operation time is obviously shortened by more than 50%, and the biopsy tissue sampling amount is improved by more than 1 time.

Drawings

FIG. 1 is a schematic diagram of an embodiment of a tissue sampler of the present invention;

FIG. 2 is an angled configuration of the sampling cannula of the tissue sampler of FIG. 1;

FIG. 3 is a schematic radial view of another embodiment of a sampling sleeve of the tissue sampler of the present invention;

FIG. 4 is a schematic view of an angle of a sampling core of the tissue sampler shown in FIG. 1.

Detailed Description

The technical scheme of the invention is described in detail in the following with reference to the accompanying drawings. Although the present invention has been described in detail with reference to the preferred embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the spirit and scope of the invention as defined in the appended claims.

Fig. 1 is a schematic structural view of an embodiment of a tissue sampler of the present invention, fig. 2 is a schematic structural view of an angle of a sampling sleeve of the tissue sampler shown in fig. 1, and fig. 4 is a schematic structural view of an angle of a sampling core rod of the tissue sampler shown in fig. 1. As shown in fig. 1 to 4, the tissue sampler of the present embodiment includes a sampling portion 10, and the sampling portion 10 includes a sampling sleeve 100, a sampling core rod 200, and a sampling slit 300. Sampling cannula 100 has a longitudinal axis (not shown), and a receiving cavity 110 disposed along the longitudinal axis. The sampling core rod 200 comprises a body 210, a distal end 220 and a proximal end 230, wherein the body 210 is arranged in the accommodating cavity 110, is in clearance fit with the accommodating cavity 110, and operates (or is installed on a cylinder or a piston) the proximal end 230, so that the body 210 reciprocates in the accommodating cavity 110 along the same direction of the longitudinal axis, and the distal end 220 is positioned outside an opening at one end of the accommodating cavity 110, thereby being beneficial to performing a puncturing operation on a target tissue during a biopsy operation. The body 210 is provided with a sampling slot 211 for receiving isolated tissues separated from the tissues and increasing the sampling amount of the tissues.

The sampling slit 300 is disposed on the sidewall 120 of the sampling cannula and is communicated with the receiving cavity 110. When the sampling incision 300 reaches the target tissue to be sampled, the sampling incision shears the target tissue by rotating the sampling cannula 100 such that the sampling cannula 100 rotates about its longitudinal axis relative to the body 210, and the excised tissue enters the sampling cannula through the sampling incision 300 and falls into and is stored in the sampling slot 211. At least 2 sampling notches 300 are provided in the sidewall 120 of the sampling cannula, such as: but are not limited to 2, 3, 4, 5, 6, etc. These sampling notches 300 are evenly distributed around the sidewall 120 of the sampling cannula.

FIG. 3 is a radial view of another embodiment of a sampling sleeve of the tissue sampler of the present invention. As shown in FIG. 3, 2 sampling cutouts 300 are provided around the sidewall 120 of the sampling cannula. Each sampling incision includes a collection opening 310 and a cutting portion 320. The collection opening 310 is disposed on the sidewall of the sampling cannula and is in communication with the receiving cavity 110.

Cutting portion 320 is attached to the sidewall of sampling cannula 100 and includes cutting end 321, collection arc 330, and cutting arc 340. The cutting end part 321 separates the collection arc part 330 from the cutting arc part 340 and is used for fixing a target tissue to be sampled and cutting the tissue at the edge of the collection opening 310 in a matching manner, the collection arc part 330 guides the tissue fixed by the cutting end part 321, so that the cut tissue enters the collection opening 310, the tissue is conveniently cut by the edge of the collection opening and the cutting end part, the cutting arc part 340 is used for assisting the cutting end part 321 to cut, and the ratio of the curvature radius of the cutting arc part 340 to the curvature radius of the side wall 120 of the sampling cannula is 1.45-1. In this embodiment, the ratio of the radius of curvature of the cutting arc 340 to the radius of curvature of the sidewall 120 of the sampling cannula is 1, i.e., the cutting arc 340 is a portion of the sidewall 120 of the sampling cannula.

To facilitate separation and sampling of the target tissue to be sampled, in the present embodiment, the cutting arc 330 is curved toward the acquisition opening 310, and includes a first arc 331 (with a radius of curvature of 0.50mm ± 0.02mm), a second arc 332 (with a radius of curvature of 3.50mm ± 0.02mm), and a third arc 333 (with a radius of curvature of 6.80mm ± 0.02 mm). The two ends of the second arc portion 332 are respectively connected with the first arc portion 331 and the second arc portion 333, the first arc portion 331 is adjacent to the cutting end portion 321, and one end of the third arc portion 333 is arranged on the side wall 120 of the sampling sleeve. First arc portion, second arc portion and third arc portion cooperate each other, carry out the outside hourglass of tissue that supplementary tissue is fixed, the guide was gathered to the tissue in proper order and get into the opening and prevent to get into the collection opening.

The tissue sampler of the embodiment can carry out directional biopsy sampling on target tissues, does not need to repeatedly prick peripheral tissues of the sampled target tissues to cause damage, and shortens the healing time of the tissues after biopsy.

Claims

1. A tissue sampler, includes the sample portion, its characterized in that sample portion include:

a sampling cannula having a longitudinal axis and a receiving cavity disposed along said longitudinal axis;

the sampling core rod comprises a body, a far end and a near end, wherein the body is arranged in the accommodating cavity and is in clearance fit with the accommodating cavity, the near end is operated, the body moves in the accommodating cavity in a reciprocating manner along the same direction of the longitudinal axis, and the far end is positioned outside an opening at one end of the accommodating cavity and is used for penetrating tissues;

2. The tissue sampler of claim 1, wherein the sampling core is provided with a sampling slot in which the captured tissue collects immediately after entering the sampling incision.

3. The tissue sampler of claim 1, wherein at least 2 sampling notches are provided in the sidewall of the sampling cannula.

4. The tissue sampler of claim 1, wherein the number of sampling slits provided in the sidewall of the sampling cannula is 2, 3, 4, 5, or 6.

5. The tissue sampler of claim 1, wherein the sampling incision comprises:

the cutting part, its with the lateral wall of sampling sleeve pipe links to each other, including cutting end, collection arc and cutting arc, cutting end with collection arc with cutting arc isolated, cutting end be used for implementing fixedly to the tissue, and with gather open-ended edge cooperation and carry out the shearing to the tissue, collection arc guide the fixed tissue of cutting end, get into collection opening, cutting arc be used for assisting cutting end implement the shearing.

6. The tissue sampler of claim 5, wherein the cutting arc is curved toward the collection opening and includes a first arc, a second arc, and a third arc, wherein the second arc is connected to the first arc and the second arc at opposite ends thereof, the first arc is adjacent to the cutting end, and one end of the third arc is disposed on the sidewall of the sampling cannula.

7. The tissue sampler of claim 6, wherein the first curved portion has a radius of curvature of 0.50mm ± 0.02mm, the second curved portion has a radius of curvature of 3.50mm ± 0.02mm, and the third curved portion has a radius of curvature of 6.80mm ± 0.02 mm.

8. The tissue sampler of claim 5, wherein the ratio of the radius of curvature of the cutting arc to the radius of curvature of the sidewall of the sampling cannula is 1.45-1.

9. The tissue sampler of claim 5, wherein the ratio of the radius of curvature of the cutting arc to the radius of curvature of the sidewall of the sampling cannula is 1.