CN110664864A - External traditional Chinese medicine patch cover for relieving rhinitis - Google Patents

External traditional Chinese medicine patch cover for relieving rhinitis Download PDF

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CN110664864A
CN110664864A CN201911157881.7A CN201911157881A CN110664864A CN 110664864 A CN110664864 A CN 110664864A CN 201911157881 A CN201911157881 A CN 201911157881A CN 110664864 A CN110664864 A CN 110664864A
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郑铁崴
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants

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Abstract

The invention provides an external traditional Chinese medicine patch cover for relieving rhinitis, which comprises an inner patch, wherein the inner patch comprises a non-woven fabric layer, a traditional Chinese medicine powder layer and a non-woven fabric layer which are distributed from top to bottom; wherein, the traditional Chinese medicine powder layer comprises the following traditional Chinese medicine raw materials: 1-5 parts of cocklebur, 5-10 parts of borneol, 6-8 parts of honeysuckle, 1-5 parts of saponin, 5-8 parts of asarum and 6-8 parts of angelica dahurica; grinding the above Chinese medicinal materials respectively to obtain superfine powder, mixing, grinding twice to obtain superfine powder, and pressing the superfine powder between two non-woven fabric layers. The external traditional Chinese medicine patch cover has a simple structure and is convenient to use; the traditional Chinese medicine has simple formula composition, is safe and efficient, has no side effect, is suitable for people of all ages, and has obvious curative effects on symptoms of obstruction of breath, rhinorrhea, sneeze and various rhinitis.

Description

External traditional Chinese medicine patch cover for relieving rhinitis
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external traditional Chinese medicine patch cover for relieving rhinitis.
Background
Rhinitis refers to inflammation of the nasal mucosa, and is an exudative inflammation in pathological tissues, and purulent inflammation and allergic inflammation are often found in the inflammation. In any case, exudation of liquidous components from blood vessels, edema, cell exudation, and hypersecretion are characteristic.
There are many rhinitis symptoms, which vary according to the type of rhinitis:
(1) chronic rhinitis is intermittently or alternatively blocked by nasal obstruction for a long time, so that dizziness is caused, and sleeping, working and learning are seriously influenced. Sticky nasal discharge often flows back into the pharyngeal cavity, resulting in cough and excessive phlegm;
(2) the initial stage of acute rhinitis is 1-2 days. Patients often have general malaise, aversion to cold, fever, inappetence, headache and the like. Nasal cavity and nasopharynx are dry and burning, itching in nose, and sneezing frequently. The acute stage is 2-5 days. The original symptoms worsen. The body temperature of adults is about 38 ℃, children are as high as more than 39 ℃, and vomiting, diarrhea, coma and even convulsion are usually caused by high fever;
(3) the drug rhinitis is used for a long time with various rhinitis drugs which hurt the nasal mucosa or laser and operation, which causes the nasal cavity to have persistent nasal obstruction and frequent nosebleed;
(4) atrophic rhinitis, bad breath, nasal secretion in block shape, tubular scab, difficult blowing, and slight nasal bleeding when the dry scab is removed by force. It is often mistaken for the initial rhinitis of cold.
With the continuous development of urban industry, the quality of air in cities is continuously reduced, the air pollution is gradually increased, various air pollutants and dust cause continuous harmful stimulation to nasal mucosa, and the incidence of simple rhinitis is gradually increased, so that the treatment of the disease is more and more emphasized by people.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides an external traditional Chinese medicine patch cover for relieving rhinitis.
In order to achieve the purpose, the technical scheme of the invention is as follows:
a topical Chinese medicinal patch cover for relieving rhinitis comprises an inner patch, wherein the inner patch comprises a non-woven fabric layer, a Chinese medicinal powder layer and a non-woven fabric layer from top to bottom; wherein, the traditional Chinese medicine powder layer comprises the following traditional Chinese medicine raw materials:
1-5 parts of cocklebur, 5-10 parts of borneol, 6-8 parts of honeysuckle, 1-5 parts of saponin, 5-8 parts of asarum and 6-8 parts of angelica dahurica; grinding the above Chinese medicinal materials respectively to obtain superfine powder, mixing, grinding twice to obtain superfine powder, and pressing the superfine powder between two non-woven fabric layers.
Further, the traditional Chinese medicine powder layer comprises the following traditional Chinese medicine raw materials: 3 parts of cocklebur, 7 parts of borneol, 7 parts of honeysuckle, 3 parts of Chinese honeylocust fruit, 7 parts of asarum and 7 parts of angelica dahurica.
Furthermore, the external nose mask also comprises an external nose mask, the external contour of the external nose mask is matched with the nose of a human body so as to cover the nostrils and the nose; the front side wall of the outer nose cover is provided with an air vent, the periphery of the inner side of the outer nose cover is provided with a circle of rubber cushion, and the inner patch is buckled at the inner side of the outer nose cover through an inner framework.
Furthermore, the inner patch is a strip with a wing part on one side, so that the inner patch is convenient to fit with nostrils and noses.
Furthermore, rubber binding rings are connected to two sides of the outer nose cover.
The traditional Chinese medicine raw materials have the following medicinal property and effect effects:
(1) and (3) cocklebur: [ WEI PROBLEMS ] is cold, pungent and bitter. [ GUIJING ] Lung, spleen and liver meridians. [ EFFECTIVE ] can dispel pathogenic wind, dispel heat, remove toxicity and kill parasites. Treating wind syndrome of head, dizziness, damp arthralgia, spasm, conjunctival congestion, nebula, wind cold, furuncle, swelling, and pyocutaneous disease;
(2) borneol: [ WEI PROBLEMS ] is cool, pungent and bitter. [ GUIJING ] Heart and lung meridians. [ EFFECTIVE ACTION ] can induce resuscitation, refresh mind, clear heat and alleviate pain. Can be used for treating fever unconsciousness, convulsion syncope, apoplexy with phlegm syncope, qi stagnation syncope, coma, conjunctival congestion, aphtha, sore throat, and purulence in ear canal;
(3) honeysuckle flower: [ PROPERTIES AND FLAVOUR ] is cold and sweet. [ GUIJING ] enters lung and stomach meridians. [ EFFECTIVE ACTION ] can clear away heat and toxic materials. For epidemic febrile disease, fever, bloody dysentery, carbuncle and external diseases, swelling, scrofula and anal fistula
(4) And (2) Chinese honeylocust fruit: [ PROPERTIES AND FLAVOURS ] WET; and (5) pungent. [ GUIJING ] Lung meridian and large intestine meridian. [ EFFECTIVE ACTION ] can dispel pathogenic wind and phlegm, remove dampness and toxic materials, and kill parasites. Treating facial distortion due to apoplexy, headache due to wind evil in the head, cough, phlegm, asthma, hematochezia due to intestinal wind, dysentery, carbuncle, swelling, and toxic materials in stool, skin ulcer, tinea, scabies, and scabies;
(5) asarum: [ PROPERTIES AND FLAVOUR ] WEN, pungent. [ GUIJING ] Heart meridian and liver meridian. [ EFFECTIVE ] can dispel pathogenic wind, dispel cold, remove water, and induce resuscitation. For wind-cold headache, nasosinusitis, toothache, phlegm and fluid retention cough, and rheumatic arthralgia;
(6) radix angelicae: radix angelicae: [ PROPERTIES AND WESTERN ] is warm, pungent and slightly bitter. [ GUIJING ] stomach, lung and spleen meridians. [ EFFECTIVE ] can dispel wind and dampness, relieve pain, relieve swelling and expel pus. Can be used for treating common cold, headache, supraorbital bone pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, and pyocutaneous disease with swelling and pain.
Has the advantages that: the external traditional Chinese medicine patch cover has a simple structure and is convenient to use; the traditional Chinese medicine has simple formula composition, is safe and efficient, has no side effect, is suitable for people of all ages, and has obvious curative effects on symptoms of obstruction of breath, rhinorrhea, sneeze and various rhinitis.
Drawings
FIG. 1 is a schematic view of an outer appearance of an inner patch according to the present invention;
fig. 2 is a schematic structural view of an external nose mask provided by the present invention.
In the figure, 1-inner patch, 2-outer nose mask, 3-inner frame, 4-rubber binding ring, 11-wing part, 21-vent and 22-rubber cushion.
Detailed Description
The invention is illustrated below with reference to specific examples. It will be understood by those skilled in the art that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention in any way.
A topical Chinese medicinal patch cover for relieving rhinitis comprises an inner patch, wherein the inner patch comprises a non-woven fabric layer, a Chinese medicinal powder layer and a non-woven fabric layer from top to bottom; wherein, the traditional Chinese medicine powder layer comprises the following traditional Chinese medicine raw materials:
1-5 parts of cocklebur, 5-10 parts of borneol, 6-8 parts of honeysuckle, 1-5 parts of saponin, 5-8 parts of asarum and 6-8 parts of angelica dahurica; grinding the above Chinese medicinal materials respectively to obtain superfine powder, mixing, grinding twice to obtain superfine powder, and pressing the superfine powder between two non-woven fabric layers;
as shown in fig. 1, the nasal mask comprises an outer nasal mask 2, an inner patch 1 is buckled on the inner side of the outer nasal mask 2 through an inner framework 3, rubber binding rings 4 are connected to two sides of the outer nasal mask 2, and the inner patch 1 is in a long strip shape with a wing part 11 on one side and is convenient to fit with nostrils and nose heads; the outer contour of the outer nose mask 2 is matched with the nose of a human body so as to cover the nostrils and the nose; the front side wall of the outer nose mask 2 is provided with a vent 21, and the periphery of the inner side is provided with a ring of rubber cushion 22. Before sleeping at night, the external nose mask 2 attached with the internal patch 1 is covered at the nostril and is fixed on the head by a rubber binding ring 4.
Example 1
A topical Chinese medicinal patch cover for relieving rhinitis is provided, wherein the Chinese medicinal powder layer comprises the following Chinese medicinal materials: 3 parts of cocklebur, 7 parts of borneol, 7 parts of honeysuckle, 3 parts of Chinese honeylocust fruit, 7 parts of asarum and 7 parts of angelica dahurica.
Example 2
A topical Chinese medicinal patch cover for relieving rhinitis is provided, wherein the Chinese medicinal powder layer comprises the following Chinese medicinal materials: 1 part of xanthium sibiricum, 5 parts of borneol, 6 parts of honeysuckle, 1 part of saponin, 5 parts of asarum and 6 parts of angelica dahurica.
Example 3
A topical Chinese medicinal patch cover for relieving rhinitis is provided, wherein the Chinese medicinal powder layer comprises the following Chinese medicinal materials: 5 parts of cocklebur, 10 parts of borneol, 8 parts of honeysuckle, 5 parts of Chinese honeylocust fruit, 8 parts of asarum and 8 parts of angelica dahurica.
Example 4
A topical Chinese medicinal patch cover for relieving rhinitis is provided, wherein the Chinese medicinal powder layer comprises the following Chinese medicinal materials: 4 parts of cocklebur, 8 parts of borneol, 7 parts of honeysuckle, 4 parts of Chinese honeylocust fruit, 6 parts of asarum and 7 parts of angelica dahurica.
Experimental observation
When 100 cases (including 20 cases of the control group) of rhinitis are treated by using the novel nasal patch of the embodiment, the curative effect and the side effect are examined, and the observed results are summarized as follows:
1. general clinical data:
the disease is classified into 64 cases of chronic rhinitis and 36 cases of allergic rhinitis according to the disease classification, wherein the symptoms are nasal obstruction, nostril itching, watery nasal discharge, sneezing and lacrimation, and partial patients have headache, dizziness and tinnitus, and other treatments are not performed before treatment.
2. Selecting an observation object: the chronic rhinitis and the allergic rhinitis have the clinical manifestations of nasal obstruction, sneezing, watery nasal discharge or mucus nasal discharge and the like.
3. The treatment scheme comprises the following steps:
the number of observed cases and groups are 20 cases for each group, the number of the cases is 20 for the control group, the total number is 100, the treatment groups in the four groups are respectively used in the groups from 1 to 4, the nose is covered before sleeping at night, the paste is ensured to be pasted for half an hour, the control group is provided with a commercially available nose paste for ventilation, the treatment course is 7 ~ 20 days for the treatment group and the control group, the sources of the cases are that the treatment group and the control group are all treated in clinic, but variable factors are required to be controlled, and the patients can only use the product and the control group.
4. The evaluation standard of curative effect is as follows:
(1) and (3) curing:
A. stage I: the disease is cured within 5 days;
B. stage II, curing in 10 ~ 15 days;
C. grade III, the medicine can be cured within 16-16 ~ 20 days without any symptoms;
D. the disease symptoms disappear more than 90%;
(2) the effect is shown: the subjective symptoms basically disappear, and no nasal obstruction, sneezing, watery nasal discharge or mucus nasal discharge and other clinical manifestations exist, and no author appears after more than 2 months of observation after the treatment is finished;
(3) the method has the following advantages: the subjective symptoms are relieved, and the clinical manifestations of nasal obstruction, sneezing, watery nasal discharge or mucus nasal discharge and the like occasionally occur, and the patients are ill again after 2 months after the treatment;
(4) and (4) invalidation: the symptoms and the onset of disease are not changed before treatment.
5. The treatment results are as follows:
(1) comparison of clinical efficacy
Table 1 clinical efficacy comparison:
Figure 490414DEST_PATH_IMAGE001
the total effective rate of the treatment group exceeds 90 percent, and the obvious effective rate exceeds 65 percent. The total effective rate of the control group is 65 percent, the obvious effective rate is 55 percent, and the curative effect of the treatment group is obviously better than that of the control group (P is less than 0.01) through analysis.
(2) The ratio of the main symptoms before and after two groups of treatments to the disappearance of swelling of nasal mucosa is compared
Table 2 the ratio of symptoms before and after treatment and disappearance of swelling of nasal mucosa was:
the results show that: except no significant difference of headache, other significant differences indicate that the treatment group is obviously superior to the control group.
(3) Side effect observation: no obvious toxic or side effect is found in the treatment group and the control group, and no allergy occurs in any case.
The results show that: the product of the invention has obviously better curative effect on rhinitis than the control group, mainly shows in the aspect of improving various symptoms of rhinitis, has definite curative effect and no toxic or side effect, and is completely suitable for various patients.

Claims (5)

1. An externally-applied traditional Chinese medicine patch cover for relieving rhinitis is characterized in that: comprises an inner patch, wherein the inner patch comprises a non-woven fabric layer, a traditional Chinese medicine powder layer and a non-woven fabric layer which are distributed from top to bottom; wherein, the traditional Chinese medicine powder layer comprises the following traditional Chinese medicine raw materials:
1-5 parts of cocklebur, 5-10 parts of borneol, 6-8 parts of honeysuckle, 1-5 parts of saponin, 5-8 parts of asarum and 6-8 parts of angelica dahurica; grinding the above Chinese medicinal materials respectively to obtain superfine powder, mixing, grinding twice to obtain superfine powder, and pressing the superfine powder between two non-woven fabric layers.
2. The externally-applied traditional Chinese medicine patch cover for relieving rhinitis as claimed in claim 1, wherein the traditional Chinese medicine powder layer comprises the following traditional Chinese medicine raw materials: 3 parts of cocklebur, 7 parts of borneol, 7 parts of honeysuckle, 3 parts of Chinese honeylocust fruit, 7 parts of asarum and 7 parts of angelica dahurica.
3. The externally-applied traditional Chinese medicine patch cover for relieving rhinitis as claimed in claim 1, further comprising an external nose mask, wherein the external contour of the external nose mask is matched with the nose of a human body so as to cover the nostrils and the nose; the front side wall of the outer nose cover is provided with an air vent, the periphery of the inner side of the outer nose cover is provided with a circle of rubber cushion, and the inner patch is buckled at the inner side of the outer nose cover through an inner framework.
4. The externally-applied traditional Chinese medicine patch cover for relieving rhinitis as claimed in claim 3, wherein the inner patch is a long strip with a wing part at one side, so as to be convenient for being attached to nostrils and nose.
5. The externally-applied traditional Chinese medicine patch cover for relieving rhinitis as claimed in claim 3 or 4, wherein rubber binding rings are connected to two sides of the external nose cover.
CN201911157881.7A 2019-11-22 2019-11-22 External traditional Chinese medicine patch cover for relieving rhinitis Pending CN110664864A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203183544U (en) * 2013-04-17 2013-09-11 魏钦江 Health-care nose mask
CN103393760A (en) * 2013-08-01 2013-11-20 赵军海 Externally-applied drug for treating rhinitis
CN206979857U (en) * 2017-06-02 2018-02-09 冯奕智 A kind of nose cup

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203183544U (en) * 2013-04-17 2013-09-11 魏钦江 Health-care nose mask
CN103393760A (en) * 2013-08-01 2013-11-20 赵军海 Externally-applied drug for treating rhinitis
CN206979857U (en) * 2017-06-02 2018-02-09 冯奕智 A kind of nose cup

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张东林: "中医外治法治疗过敏性鼻炎38例体会", 《实用中西医结合临床》 *
朱卫民,编: "《中医美容》", 30 June 1994, 西安出版社 *

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