CN110591821A - Method for extracting sweet wormwood essential oil - Google Patents
Method for extracting sweet wormwood essential oil Download PDFInfo
- Publication number
- CN110591821A CN110591821A CN201910883649.5A CN201910883649A CN110591821A CN 110591821 A CN110591821 A CN 110591821A CN 201910883649 A CN201910883649 A CN 201910883649A CN 110591821 A CN110591821 A CN 110591821A
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- CN
- China
- Prior art keywords
- extraction
- stirring
- oil
- extracting
- essential oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000001405 Artemisia annua Nutrition 0.000 title claims abstract description 37
- 240000000011 Artemisia annua Species 0.000 title claims abstract description 37
- 239000000341 volatile oil Substances 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 title claims abstract description 16
- 238000000605 extraction Methods 0.000 claims abstract description 28
- 239000003921 oil Substances 0.000 claims abstract description 23
- 238000003756 stirring Methods 0.000 claims abstract description 18
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000001914 filtration Methods 0.000 claims abstract description 14
- 238000010992 reflux Methods 0.000 claims abstract description 14
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000000706 filtrate Substances 0.000 claims abstract description 12
- 238000001179 sorption measurement Methods 0.000 claims abstract description 12
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000002904 solvent Substances 0.000 claims abstract description 8
- 239000007788 liquid Substances 0.000 claims abstract description 4
- 239000000203 mixture Substances 0.000 claims abstract description 4
- 239000002699 waste material Substances 0.000 abstract description 11
- 230000008901 benefit Effects 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 230000000694 effects Effects 0.000 description 4
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 description 3
- 229960004191 artemisinin Drugs 0.000 description 3
- 229930101531 artemisinin Natural products 0.000 description 3
- 239000006227 byproduct Substances 0.000 description 3
- 238000009776 industrial production Methods 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- HATRDXDCPOXQJX-UHFFFAOYSA-N Thapsigargin Natural products CCCCCCCC(=O)OC1C(OC(O)C(=C/C)C)C(=C2C3OC(=O)C(C)(O)C3(O)C(CC(C)(OC(=O)C)C12)OC(=O)CCC)C HATRDXDCPOXQJX-UHFFFAOYSA-N 0.000 description 1
- 239000003430 antimalarial agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 229930009674 sesquiterpene lactone Natural products 0.000 description 1
- 150000002107 sesquiterpene lactone derivatives Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/022—Refining
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Fats And Perfumes (AREA)
- Extraction Or Liquid Replacement (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
Abstract
The invention discloses a method for extracting sweet wormwood essential oil, which comprises the following steps: (1) hot reflux extraction: performing hot reflux extraction on Artemisia annua wax oil for 2 times by using anhydrous methanol or ethanol or mixture of the two as solvent, wherein the material-liquid ratio of the Artemisia annua wax oil to the solvent is 1:15, the extraction temperature is 50-60 deg.C, the extraction time is 40min, and extracting under hot reflux to obtain extractive solution; (2) and (3) reduced pressure centrifugal filtration: collecting the extracting solution obtained in the step (1), stirring, adding 4% of activated carbon in the stirring process for adsorption, stirring at 50-60 ℃ for 40min, and performing reduced pressure centrifugal filtration after stirring to obtain filtrate; (3) concentration: recovering ethanol from the filtrate in the step (2), concentrating to obtain oil, and extracting with an essential oil extraction tank to obtain Artemisia annua essential oil; the method has the advantages of utilizing the waste sweet wormwood wax oil, improving the resource utilization rate, reducing the pollution of waste to the environment, reducing the production cost and improving the economic benefit.
Description
Technical Field
The invention relates to the field of sweet wormwood essential oil extraction, and particularly relates to a sweet wormwood essential oil extraction method.
Background
The artemisinin is a compound containing peroxy bridge sesquiterpene lactone extracted from the Chinese medicine artemisia annua, is an efficient and low-toxicity antimalarial drug, can generate a plurality of byproducts in the extraction process of the artemisinin, the byproducts are generally used as wastes to be treated, the treatment difficulty is high, the environment is polluted, the artemisia annua wax oil is a byproduct in the extraction of the artemisinin, the artemisia annua wax oil can be recycled through an extraction process, the direct waste of the artemisia annua wax oil causes resource waste, and the requirement of industrial production cannot be met.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides the method for extracting the sweet wormwood essential oil, which utilizes the waste sweet wormwood wax oil, improves the resource utilization rate, reduces the pollution of waste to the environment, reduces the production cost and improves the economic benefit.
The purpose of the invention is realized as follows: the extraction method of the sweet wormwood essential oil comprises the following steps:
(1) hot reflux extraction: performing hot reflux extraction on Artemisia annua wax oil for 2 times by using anhydrous methanol or ethanol or mixture of the two as solvent, wherein the material-liquid ratio of the Artemisia annua wax oil to the solvent is 1:15, the extraction temperature is 50-60 deg.C, the extraction time is 40min, and extracting under hot reflux to obtain extractive solution;
(2) and (3) reduced pressure centrifugal filtration: collecting the extracting solution obtained in the step (1), stirring, adding 4% of activated carbon in the stirring process for adsorption, stirring at 50-60 ℃ for 40min, and performing reduced pressure centrifugal filtration after stirring to obtain filtrate;
(3) concentration: recovering ethanol from the filtrate in the step (2), concentrating to obtain oil, and extracting with an essential oil extraction tank to obtain Artemisia annua essential oil.
The invention has the following beneficial effects: the invention discloses a method for extracting sweet wormwood essential oil, wherein sweet wormwood wax oil is subjected to thermal reflux treatment to obtain an extracting solution, the extracting solution is firstly subjected to adsorption decoloration through 4% of active carbon to enable the solution to be purer, stirring is continuously performed in the adsorption decoloration process to improve the adsorption effect and efficiency, the extracting solution subjected to adsorption decoloration is subjected to reduced pressure centrifugal filtration to obtain a filtrate, sweet wormwood oil is separated from impurities through centrifugation to improve the filtration effect and the product purity, and the filtrate subjected to reduced pressure centrifugal filtration is concentrated and extracted to obtain the sweet wormwood essential oil; the method has the advantages of utilizing the waste sweet wormwood wax oil, improving the resource utilization rate, reducing the pollution of waste to the environment, reducing the production cost, improving the economic benefit and meeting the requirements of industrial production.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
The extraction method of the sweet wormwood essential oil comprises the following steps:
(1) hot reflux extraction: performing hot reflux extraction on Artemisia annua wax oil for 2 times by using anhydrous methanol or ethanol or mixture of the two as solvent, wherein the material-liquid ratio of the Artemisia annua wax oil to the solvent is 1:15, the extraction temperature is 50-60 deg.C, the extraction time is 40min, and extracting under hot reflux to obtain extractive solution;
(2) and (3) reduced pressure centrifugal filtration: collecting the extracting solution obtained in the step (1), stirring, adding 4% of activated carbon in the stirring process for adsorption, stirring at 50-60 ℃ for 40min, and performing reduced pressure centrifugal filtration after stirring to obtain filtrate;
(3) concentration: recovering ethanol from the filtrate in the step (2), concentrating to obtain oil, and extracting with an essential oil extraction tank to obtain Artemisia annua essential oil.
The invention discloses a method for extracting sweet wormwood essential oil, wherein sweet wormwood wax oil is subjected to thermal reflux treatment to obtain an extracting solution, the extracting solution is firstly subjected to adsorption decoloration through 4% of active carbon to enable the solution to be purer, stirring is continuously performed in the adsorption decoloration process to improve the adsorption effect and efficiency, the extracting solution subjected to adsorption decoloration is subjected to reduced pressure centrifugal filtration to obtain a filtrate, sweet wormwood oil is separated from impurities through centrifugation to improve the filtration effect and the product purity, and the filtrate subjected to reduced pressure centrifugal filtration is concentrated and extracted to obtain the sweet wormwood essential oil; the method has the advantages of utilizing the waste sweet wormwood wax oil, improving the resource utilization rate, reducing the pollution of waste to the environment, reducing the production cost, improving the economic benefit and meeting the requirements of industrial production.
Claims (1)
1. The extraction method of the sweet wormwood essential oil is characterized by comprising the following steps: the method comprises the following steps:
hot reflux extraction: performing hot reflux extraction on Artemisia annua wax oil for 2 times by using anhydrous methanol or ethanol or mixture of the two as solvent, wherein the material-liquid ratio of the Artemisia annua wax oil to the solvent is 1:15, the extraction temperature is 50-60 deg.C, the extraction time is 40min, and extracting under hot reflux to obtain extractive solution;
and (3) reduced pressure centrifugal filtration: collecting the extracting solution obtained in the step (1), stirring, adding 4% of activated carbon in the stirring process for adsorption, stirring at 50-60 ℃ for 40min, and performing reduced pressure centrifugal filtration after stirring to obtain filtrate;
concentration: recovering ethanol from the filtrate in the step (2), concentrating to obtain oil, and extracting with an essential oil extraction tank to obtain Artemisia annua essential oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910883649.5A CN110591821A (en) | 2019-09-18 | 2019-09-18 | Method for extracting sweet wormwood essential oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910883649.5A CN110591821A (en) | 2019-09-18 | 2019-09-18 | Method for extracting sweet wormwood essential oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110591821A true CN110591821A (en) | 2019-12-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910883649.5A Pending CN110591821A (en) | 2019-09-18 | 2019-09-18 | Method for extracting sweet wormwood essential oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110591821A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110623002A (en) * | 2019-09-18 | 2019-12-31 | 禹州市天源生物科技有限公司 | Preparation method of sweet wormwood wax oil insect repellent |
| CN113105947A (en) * | 2021-04-21 | 2021-07-13 | 禹州市天源生物科技有限公司 | Preparation method of sweet wormwood essential oil |
| CN113304180A (en) * | 2021-05-28 | 2021-08-27 | 禹州市天源生物科技有限公司 | Artemisia oil pet antibacterial spray and preparation method thereof |
| CN114437869A (en) * | 2021-12-15 | 2022-05-06 | 河南天源药物研究有限公司 | Natural cool sweet wormwood essential oil and extraction process thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102517152A (en) * | 2011-11-14 | 2012-06-27 | 牛江林 | Method for extracting artemisia annua oil and artemisia annua dew from artemisia annua |
| CN103483350A (en) * | 2013-06-25 | 2014-01-01 | 重庆华方武陵山制药有限公司 | Ultrasonic reflux extraction method of artemisinin |
| CN104530059A (en) * | 2015-01-12 | 2015-04-22 | 吉首大学 | Artemisia annua wax oil sodium copper chlorophyllin and preparation method thereof |
| CN208762473U (en) * | 2018-08-21 | 2019-04-19 | 陕西必康制药集团控股有限公司 | Traditional medicine volatile oil extraction element and traditional medicine volatile oil extract equipment |
| CN209292317U (en) * | 2018-12-07 | 2019-08-23 | 贵州鼎立生物科技香料有限公司 | A kind of Rosa Damascana extractor |
-
2019
- 2019-09-18 CN CN201910883649.5A patent/CN110591821A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102517152A (en) * | 2011-11-14 | 2012-06-27 | 牛江林 | Method for extracting artemisia annua oil and artemisia annua dew from artemisia annua |
| CN103483350A (en) * | 2013-06-25 | 2014-01-01 | 重庆华方武陵山制药有限公司 | Ultrasonic reflux extraction method of artemisinin |
| CN104530059A (en) * | 2015-01-12 | 2015-04-22 | 吉首大学 | Artemisia annua wax oil sodium copper chlorophyllin and preparation method thereof |
| CN208762473U (en) * | 2018-08-21 | 2019-04-19 | 陕西必康制药集团控股有限公司 | Traditional medicine volatile oil extraction element and traditional medicine volatile oil extract equipment |
| CN209292317U (en) * | 2018-12-07 | 2019-08-23 | 贵州鼎立生物科技香料有限公司 | A kind of Rosa Damascana extractor |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110623002A (en) * | 2019-09-18 | 2019-12-31 | 禹州市天源生物科技有限公司 | Preparation method of sweet wormwood wax oil insect repellent |
| CN113105947A (en) * | 2021-04-21 | 2021-07-13 | 禹州市天源生物科技有限公司 | Preparation method of sweet wormwood essential oil |
| CN113304180A (en) * | 2021-05-28 | 2021-08-27 | 禹州市天源生物科技有限公司 | Artemisia oil pet antibacterial spray and preparation method thereof |
| CN114437869A (en) * | 2021-12-15 | 2022-05-06 | 河南天源药物研究有限公司 | Natural cool sweet wormwood essential oil and extraction process thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191220 |