CN110583695A - Drug for preventing and treating mice - Google Patents

Drug for preventing and treating mice Download PDF

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Publication number
CN110583695A
CN110583695A CN201910955917.XA CN201910955917A CN110583695A CN 110583695 A CN110583695 A CN 110583695A CN 201910955917 A CN201910955917 A CN 201910955917A CN 110583695 A CN110583695 A CN 110583695A
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CN
China
Prior art keywords
parts
medicament
mice
mouse
quicklime powder
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Pending
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CN201910955917.XA
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Chinese (zh)
Inventor
彭乃闩
彭霞
彭军
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Shenzhen 3a Pest Control Co Ltd
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Shenzhen 3a Pest Control Co Ltd
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Priority to CN201910955917.XA priority Critical patent/CN110583695A/en
Publication of CN110583695A publication Critical patent/CN110583695A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10Macromolecular compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/24Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/06Aluminium; Calcium; Magnesium; Compounds thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/16Heavy metals; Compounds thereof

Abstract

The invention relates to the technical field of mouse control, and provides a mouse control medicament aiming at the problem that the mouse control medicament is easy to mildew, which comprises the following steps: the paint comprises the following components in parts by mass: 10-25 parts of quicklime powder; 20-50 parts of apolipoprotein; 10-25 parts of beeswax; 40-70 parts of saccharides; 15-30 parts of nano aluminum oxide; 5-20 parts of calcium stearate; the quicklime powder is pressed into particles, calcium stearate wraps the particle quicklime powder, and the moisture absorption and porosity of the nano-alumina are good, so that water can enter the nano-alumina through the pores, the water entering the quicklime powder and the apolipoprotein is reduced, substances such as bacteria are not easy to breed in the apolipoprotein, the mildew condition of the mouse control agent is reduced, the mouse control agent is placed on the ground, mice can be trapped and killed for a long time, and the living environment of people is not easy to be affected.

Description

Drug for preventing and treating mice
Technical Field
The invention relates to the technical field of mouse control, in particular to a medicament for controlling mice.
Background
The mouse is a rodent of the mammalia, rodentia and muridae, commonly called a "rat", and is an animal which can breed quickly and has strong viability. There are about three thousand kinds of rats all over the world, and the footprints of the rats can be seen indoors and outdoors, and the rats are often exposed in sewers, toilets, kitchens and other places, and frequently move back and forth between a germ-carrying place and a clean place, so that pathogenic bacteria are transmitted through rat feet, body hair and stomach carried objects.
In order to kill rats, intestinal rodenticides such as warfarin, glyphosate, diphacinone sodium salt, muraphos and other chemical drugs are frequently used, the rodenticides are mixed with substances which mice like to eat to form a medicament for trapping and killing rats, the mice are induced to eat the rodenticides while being fed to trap and kill rats, but the rats like to eat proteins and saccharides, the substances are easy to mildew after being affected with damp, so that the medicament for trapping and killing rats can absorb moisture, the medicament for trapping and killing rats can mildew, the living environment of people is influenced, and therefore, the improvement space is provided.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the medicament for preventing and treating the mice, which has the advantage of difficult mildewing.
In order to achieve the purpose, the invention provides the following technical scheme:
the medicament for preventing and treating the rats comprises the following components in parts by weight:
10-25 parts of quicklime powder;
20-50 parts of apolipoprotein;
10-25 parts of beeswax;
40-70 parts of saccharides;
15-30 parts of nano aluminum oxide;
5-20 parts of calcium stearate;
the quicklime powder is pressed into particles, and the calcium stearate wraps the granular quicklime powder.
The invention is further configured to: the paint comprises the following components in parts by mass:
15-25 parts of quicklime powder;
20-40 parts of apolipoprotein;
10-20 parts of beeswax;
50-70 parts of saccharides;
15-25 parts of nano aluminum oxide;
10-20 parts of calcium stearate;
the quicklime powder is pressed into particles, and the calcium stearate wraps the granular quicklime powder.
By adopting the technical scheme, the nano-alumina is added, and the better hygroscopicity and porosity of the nano-alumina are utilized, so that water can enter the nano-alumina through the pores, the water entering quicklime powder and the apolipoprotein is reduced, substances such as bacteria and the like are not easy to breed in the apolipoprotein, the mildew condition of the mouse control agent is reduced, the mouse control agent can be placed on the ground to trap and kill mice for a long time, and the living environment of people is not easy to influence;
by adding the apolipoprotein and the saccharides, the mice can easily find the medicament for preventing and treating the mice and eat the medicament, so that the trapping rate of the medicament for preventing and treating the mice is improved;
the beeswax is added into the medicament to form a barrier, so that moisture in the air is not easy to enter the saccharides, the damp condition of the saccharides is reduced, and the medicament for preventing and treating mice is not easy to breed bacteria;
the quicklime powder is pressed into particles, calcium stearate wraps the particle quicklime powder, and the calcium stearate has good hygroscopicity, so that when the mouse control medicament is placed on the ground, moisture is not easy to enter the quicklime powder to react with the quicklime powder to release heat, the condition that the quicklime powder is dry is kept, and meanwhile, when a mouse eats the mouse control medicament, the condition that the mouse vomits due to the fact that the quicklime powder directly contacts with the moisture in the oral cavity of the mouse to release a large amount of heat is reduced when the mouse swallows the medicament, and the mouse is benefited to eat the mouse control medicament;
by adding calcium stearate into the medicament, after the medicament for preventing and treating mice is eaten by mice, the calcium stearate enters the body of the mice to react with gastric acid in the body of the mice, so that the calcium stearate is dissolved, quicklime powder wrapped by the calcium stearate is exposed, and then the quicklime powder reacts with water in the body of the mice to release a large amount of heat, so that the mice die due to too high internal temperature.
The invention is further configured to: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
2-4 parts of methyl cellulose.
By adopting the technical scheme, the medicament for preventing and treating the mice is easily prepared into various shapes by adding the methyl cellulose into the medicament and utilizing the thickening property of the methyl cellulose, so that the medicament for preventing and treating the mice is convenient to carry.
The invention is further configured to: the saccharide comprises one or more of brown sugar, glucose, white sugar and honey.
By adopting the technical scheme, the mouse can easily find the medicament for preventing and treating the mouse, and then the mouse is fed with the medicament for preventing and treating the mouse, so that the feeding attracting effect is better.
The invention is further configured to: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
and 2-4 parts of inulin.
By adopting the technical scheme, inulin is added, so that fructose and glucose are obtained during hydrolysis of the inulin, the content of saccharides is increased, and the food calling effect is improved.
The invention is further configured to: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
1-3 parts of nano titanium sol.
By adopting the technical scheme, the nano titanium sol is added, and the medicament for controlling the mice is irradiated by sunlight, so that the nano titanium sol can catalyze ultraviolet rays in the sunlight to achieve the sterilization effect, and the medicament for controlling the mice is not easy to generate bacteria.
The invention is further configured to: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
0.01-0.1 part of 2-octyl-4-isothiazolin-3-ketone.
By adopting the technical scheme, the 2-octyl-4-isothiazolin-3-one is added, so that the food calling effect is effectively improved, the food calling effect of the mouse control agent is better, and the mouse trapping and killing rate is improved.
The invention is further configured to: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
2-4 parts of attapulgite.
Through adopting above-mentioned technical scheme, through adding attapulgite in the medicament for the medicament of prevention and cure mouse has better thixotropy, increases the mobility when hot melt beeswax adds man-hour, and after the beeswax solidification, mobility descends by a wide margin, makes the stability of the medicament of prevention and cure mouse preferred, keeps the shape of the medicament of prevention and cure mouse more easily.
The invention is further configured to: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
3-5 parts of nano silicon dioxide.
By adopting the technical scheme, the nano silicon dioxide is added, so that the isolation layer is formed when the nano aluminum oxide and the beeswax are mixed, the flow of the medicament for preventing and treating mice during preparation can be inhibited, the adhesive force of each raw material of the medicament for preventing and treating mice is improved, and the curing degree of the medicament for preventing and treating mice is accelerated.
The invention is further configured to: the preparation method of the medicament for preventing and treating the rats comprises the following steps:
s1, heating and boiling saccharides to form syrup, adding nano-alumina and beeswax into the syrup, and mixing to form a primary premixed solution;
s2, pressing quicklime powder into particles at room temperature, and then wrapping the calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid and apolipoprotein into the primary premix and uniformly stirring to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressurizing, cooling and solidifying to form a mouse control medicament.
By adopting the technical scheme, the surface of the medicament for controlling the mice is the saccharides, so that the food calling effect is better, the medicament for controlling the mice is injected into the mould for pressurizing and cooling, the medicament for controlling the mice is more stable after being solidified, the medicaments for controlling the mice can be made into substances with various shapes through the mould so as to trap and kill the mice, and the mouse trapping and killing rate is improved.
In conclusion, the invention has the following beneficial effects:
1. the nano-alumina is easily dispersed in the beeswax to form a turbid mixture, and the good hygroscopicity and porosity of the nano-alumina are utilized, so that water can enter the nano-alumina through the pores, the water entering quicklime powder and apolipoprotein is reduced, substances such as bacteria are not easy to breed in the apolipoprotein, the mildew condition of the rat control agent is reduced, the rat control agent can be placed on the ground to trap and kill rats for a long time, and the condition affecting the living environment of people is reduced;
2. the calcium stearate is wrapped with the granular quicklime powder, after the mice eat the medicament, the calcium stearate enters the mice to react with gastric acid in the mice, so that the calcium stearate is dissolved, the quicklime powder wrapped by the calcium stearate is exposed, and further the quicklime powder reacts with water in the mice to release a large amount of heat, so that the mice die due to too high internal temperature;
3. by adding inulin, fructose and glucose are obtained during inulin hydrolysis, the content of saccharides is increased, and the food calling effect is improved.
Drawings
FIG. 1 is a schematic flow chart of a method for preparing the rat control agent of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples.
In the following examples, quicklime powder sold by bright trade company ltd of new market is used as quicklime powder.
In the following examples, apolipoproteins sold by Shanghai Guanxiang Biotechnology, Inc. were used as apolipoproteins.
In the following examples, beeswax was sold by chemical technology limited Lin, Guangzhou, Inc.
In the following examples, the brown sugar, glucose, white sugar and honey are all sugars sold by Zhengzhou national de-s-chemical products GmbH.
In the following examples, the nano alumina is sold by Nanjing Baokte New Material Co.
In the following examples, calcium stearate sold by Chongqing chemical trade company Limited is used.
In the following examples, attapulgite sold by new materials ltd, yue jiang is used as the attapulgite.
In the following examples, methylcellulose available from Guangdong south China New Material Co., Ltd is used.
In the following examples, sesame oil sold by Guanghan excellence industries, Inc., Sichuan province was used as the sesame oil.
In the following examples, inulin sold by Suzhou Huixuan Biotech Co., Ltd is used as inulin.
In the following examples, the nano titanium sol sold by Jiangsu Tianxing New Material Co., Ltd is used.
In the following examples, 2-octyl-4-isothiazolin-3-one was 2-octyl-4-isothiazolin-3-one sold by Ipperiopsis Hubeiensis chemical Co., Ltd.
In the following examples, sunflower seed oil sold by Dow Xiangmoni edible oil, LLC is used as the sunflower seed oil.
In the following examples, the nano-silica was a nano-titanium sol sold by Jiangsu Tianxing New Material Co.
Example 1
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 10kg of brown sugar, 10kg of glucose, 10kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling the mixture to form syrup, heating the syrup to 50 ℃, and then adding 15kg of nano-alumina and 10kg of beeswax into the syrup to mix to form a primary premixed liquid in a molten state;
s2, pressing 10kg of quicklime powder into particles at room temperature, and then wrapping 5kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding the solid and 20kg of apolipoprotein into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 2
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 10kg of glucose, 10kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 20kg of nano-alumina and 15kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 15kg of quicklime powder into particles at room temperature, and then wrapping 10kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding the solid and 30kg of apolipoprotein into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 3
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 10kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling the mixture to form syrup, heating the syrup to 50 ℃, and then adding 25kg of nano-alumina and 20kg of beeswax into the syrup to mix to form a primary premixed liquid in a molten state;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 15kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding the solid and 40kg of apolipoprotein into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 4
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 20kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 30kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 25kg of quicklime powder into particles at room temperature, and then wrapping 20kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding the solid and 50kg of apolipoprotein into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 5
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding the solid and 45kg of apolipoprotein into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 6
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 2kg of methyl cellulose, 2kg of inulin, 1kg of nano titanium sol, 0.01kg of 2-octyl-4-isothiazolinone-3-ketone, 2kg of attapulgite and 3kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 7
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 3kg of methyl cellulose, 3kg of inulin, 2kg of nano titanium sol, 0.05kg of 2-octyl-4-isothiazolinone-3-ketone, 3kg of attapulgite and 4kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 8
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 4kg of methyl cellulose, 4kg of inulin, 3kg of nano titanium sol, 0.1kg of 2-octyl-4-isothiazolinone-3-ketone, 4kg of attapulgite and 5kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Example 9
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 2kg of methyl cellulose, 3kg of inulin, 2kg of nano titanium sol, 0.06kg of 2-octyl-4-isothiazoline-3-one, 2kg of attapulgite and 4kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Comparative example 1
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, adding 12kg of calcium stearate, 45kg of apolipoprotein, 20kg of brown sugar, 20kg of glucose, 15kg of white sugar, 10kg of honey, 2kg of methylcellulose, 3kg of inulin, 2kg of nano titanium sol, 0.06kg of 2-octyl-4-isothiazolinone, 2kg of attapulgite and 4kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min, and rotating at the speed of 60r/min to form a secondary premixed solution;
and S3, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Comparative example 2
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 25kg of beeswax into the syrup to mix to form a primary premixed liquid in a molten state;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 2kg of methyl cellulose, 3kg of inulin, 2kg of nano titanium sol, 0.06kg of 2-octyl-4-isothiazoline-3-one, 2kg of attapulgite and 4kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Comparative example 3
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 2kg of methyl cellulose, 2kg of nano titanium sol, 0.06kg of 2-octyl-4-isothiazoline-3-ketone, 2kg of attapulgite and 4kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Comparative example 4
A preparation for preventing and treating mice is prepared by the following steps:
s1, adding 20kg of brown sugar, 20kg of glucose, 15kg of white sugar and 10kg of honey into a stirring kettle, heating and boiling to form syrup, heating to 50 ℃, and then adding 28kg of nano-alumina and 25kg of beeswax into the syrup to mix to form a molten primary premixed solution;
s2, pressing 20kg of quicklime powder into particles at room temperature, and then wrapping 12kg of calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid, 45kg of apolipoprotein, 2kg of methyl cellulose, 3kg of inulin, 2kg of nano titanium sol, 2kg of attapulgite and 4kg of nano silicon dioxide into a stirring kettle, uniformly stirring for 15min at a rotating speed of 60r/min to form a secondary premixed solution;
and S4, injecting the secondary premixed liquid into a mold, pressing, wherein the pressing pressure is 2MPa, cooling and solidifying the secondary premixed liquid in the mold to form the mouse control medicament, and taking out the medicament when the mold is cooled to the normal temperature.
Test 1
Placing three iron buckets (the diameter is 500cm, the height is 100cm) capable of containing 200 mice respectively, taking a certain amount of dry wood chips to be placed in the iron buckets, wherein the thickness of the wood chips is about 10-20mm, spraying a proper amount of distilled water on the wood chips by using a small spraying pot to keep the wood chips moist, placing drinking boxes for the mice to drink water in the iron buckets, uniformly placing plastic cups (the diameter is 30cm, the height is 10cm) in the iron buckets, arranging a group of the plastic cups in each iron bucket according to each embodiment and each comparative example, wherein 13 plastic cups are arranged in each iron bucket, the plastic cups are 39 plastic cups in total, randomly arranging and numbering the plastic cups, taking 2g of the mouse control medicament of each embodiment and each comparative example to be placed in the plastic cups respectively, and arranging an opening at one side of each plastic cup; placing 50 mice in the center of an iron barrel, adjusting the temperature (27 +/-1 ℃) and the humidity (85 +/-5% RH) in a laboratory, and keeping the dark condition in the laboratory for test; 8: 00. 19: 00 observing for 1 time respectively, and observing and recording the number of mice in each plastic cup; in total observation 5d, the cumulative number of mice appearing in the plastic cup is counted, the relative response rate of the mice to the mouse-controlling medicaments of the examples and the comparative examples is calculated according to the following formula, and the relative response rate of the mouse-controlling medicaments accumulating the number of the mice is set as 100%; the relative reaction rate reflects the degree of preference of the mice for the mouse-controlling medicament, and the larger the numerical value is, the stronger the mice have the preference for the mouse-controlling medicament is proved; the mold formation of the examples and comparative examples was observed simultaneously during the test.
Test 2
Placing three iron buckets (the diameter is 500cm, the height is 100cm) capable of containing 200 mice respectively, taking a certain amount of dry wood chips to be placed in the iron buckets, wherein the thickness of the wood chips is about 10-20mm, spraying a proper amount of distilled water on the wood chips by using a small spraying pot to keep the wood chips moist, placing drinking boxes for the mice to drink water in the iron buckets, uniformly placing plastic cups (the diameter is 30cm, the height is 10cm) in the iron buckets, arranging a group of the plastic cups in each iron bucket according to each embodiment and each comparative example, wherein 13 plastic cups are arranged in each iron bucket, the plastic cups are 39 plastic cups in total, randomly arranging and numbering the plastic cups, taking 2g of the mouse control medicament of each embodiment and each comparative example to be placed in the plastic cups respectively, and arranging an opening at one side of each plastic cup; 50 mice are placed in the center of an iron bucket, the temperature (27 +/-1 ℃) and the humidity (85 +/-5% RH) in a laboratory are adjusted, the dark condition in the laboratory is kept for carrying out test testing, and the death condition of the mice is analyzed after 5 days of observation to obtain the death rate of the mice.
Specific test data are shown in Table 1
TABLE 1
Relative rate of reaction Degree of mildew formation Mortality rate
Example 1 93 Without mildew 93
Example 2 94 Without mildew 94
Example 3 94 Without mildew 94
Example 4 95 Without mildew 95
Example 5 95 Without mildew 95
Example 6 98 Without mildew 98
Example 7 98 Without mildew 98
Example 8 99 Without mildew 99
Example 9 100 Without mildew 100
Comparative example 1 100 Without mildew 0
Comparative example 2 85 Severe mildew 85
Comparative example 3 97 Without mildew 97
Comparative example 4 96 Without mildew 96
As can be seen from Table 1, the mouse can be effectively killed by adding the quicklime powder, and the life quality of people is effectively improved.
By adding the nano-alumina, the mildew condition of the mouse-controlling medicament can be effectively reduced, so that the mouse-controlling medicament can be stored for a longer time, and the influence on the living environment of people is reduced.
By adding inulin and 2-octyl-4-isothiazolin-3-one, the effect of the mouse control medicament on food calling is better, more mice are attracted to eat the mouse control medicament, the mice are easier to eat the mouse control medicament to be trapped and killed, and the mouse trapping and killing rate is improved.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.

Claims (10)

1. A medicament for controlling mice is characterized in that: the paint comprises the following components in parts by mass:
10-25 parts of quicklime powder;
20-50 parts of apolipoprotein;
10-25 parts of beeswax;
40-70 parts of saccharides;
15-30 parts of nano aluminum oxide;
5-20 parts of calcium stearate;
the quicklime powder is pressed into particles, and the calcium stearate wraps the granular quicklime powder.
2. A mouse-controlling agent according to claim 1, wherein: the paint comprises the following components in parts by mass:
15-25 parts of quicklime powder;
20-40 parts of apolipoprotein;
10-20 parts of beeswax;
50-70 parts of saccharides;
15-25 parts of nano aluminum oxide;
10-20 parts of calcium stearate;
the quicklime powder is pressed into particles, and the calcium stearate wraps the granular quicklime powder.
3. A mouse-controlling agent according to claim 2, wherein: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
2-4 parts of methyl cellulose.
4. A mouse-controlling agent according to claim 1, wherein: the saccharide comprises one or more of brown sugar, glucose, white sugar and honey.
5. A mouse-controlling agent according to claim 4, wherein: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
and 2-4 parts of inulin.
6. A mouse-controlling agent according to claim 1, wherein: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
1-3 parts of nano titanium sol.
7. A mouse-controlling agent according to claim 1, wherein: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
0.01-0.1 part of 2-octyl-4-isothiazolin-3-ketone.
8. A mouse-controlling agent according to claim 1, wherein: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
2-4 parts of attapulgite.
9. A mouse-controlling agent according to claim 1, wherein: the medicament for preventing and treating the mice also comprises the following components in parts by weight:
3-5 parts of nano silicon dioxide.
10. A mouse-controlling agent according to claim 1, wherein: the preparation method of the medicament for preventing and treating the rats comprises the following steps:
s1, heating and boiling saccharides to form syrup, adding nano-alumina and beeswax into the syrup, and mixing to form a primary premixed solution;
s2, pressing quicklime powder into particles at room temperature, and then wrapping the calcium stearate on the particle quicklime powder to form a solid substance;
s3, adding a solid and apolipoprotein into the primary premix and uniformly stirring to form a secondary premix;
and S4, injecting the secondary premixed liquid into a mold, pressurizing, cooling and solidifying to form a mouse control medicament.
CN201910955917.XA 2019-10-09 2019-10-09 Drug for preventing and treating mice Pending CN110583695A (en)

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