CN110559187A - Granular medicine extrusion granulation production device - Google Patents
Granular medicine extrusion granulation production device Download PDFInfo
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- CN110559187A CN110559187A CN201910956097.6A CN201910956097A CN110559187A CN 110559187 A CN110559187 A CN 110559187A CN 201910956097 A CN201910956097 A CN 201910956097A CN 110559187 A CN110559187 A CN 110559187A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
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Abstract
The invention discloses a granular drug extrusion granulation production device, which relates to the technical field of drug production and comprises a support frame, wherein a stirring barrel is fixedly arranged on the support frame, a cutting mechanism driven by a transmission motor is arranged at the bottom of an extrusion mechanism, a collecting tank is arranged below an extrusion pipe, and a dispersing mechanism is arranged inside the collecting tank; according to the invention, the medicine raw materials are stirred and mixed in a rotating manner through the arranged mixing mechanism, so that the medicine raw materials of all components can be fully and uniformly stirred, the medicine obtained by extrusion granulation has full efficacy, the arranged extrusion mechanism is used for extruding the raw materials from the extrusion holes, the cutting mechanism is used for cutting and granulating the strip-shaped raw materials extruded from the extrusion holes, the arranged hot air machine is used for quickly drying the medicine, the granular medicine is quickly formed, and the arranged dispersing mechanism is used for promoting the volatilization of the water of the medicine, so that the forming efficiency is further improved.
Description
Technical Field
The invention relates to the technical field of medicine production, in particular to a granular medicine extrusion granulation production device.
Background
Pharmaceutical engineering is a science and technology that intersects chemistry, biology, pharmacy and engineering, and aims to develop, amplify and design talents involved in drug research and development, new processes, new equipment and new varieties. In the process of processing and producing granular medicines, the raw materials of the medicines need to be granulated by extrusion granulation equipment to obtain the granular medicines.
The patent with the publication number of CN208598812U discloses a drug granulating and drying integrated device, which comprises a granulating chamber positioned at the upper part and a drying chamber positioned at the lower part, wherein a feed inlet provided with a feed valve is arranged at the top of the granulating chamber, a press roller with lines is arranged in the granulating chamber, one end of the press roller is connected with a driving component consisting of a motor and a speed reducer through a rotating shaft, a sieving cover provided with sieve holes is arranged below the press roller, drug materials enter the granulating chamber through the feed inlet and are extruded into granules through the actions of the press roller and the sieving cover; the drying chamber is internally and transversely provided with a tube bundle consisting of heat exchange tubes, the two ends of the tube bundle are respectively provided with an inlet distribution water tank and an outlet distribution water tank, the inlet distribution water tank is provided with an inlet tube, the outlet distribution water tank is provided with an outlet tube, medicine particles made in the granulating chamber penetrate through the tube bundle consisting of the heat exchange tubes from top to bottom, and the drying is completed by heat exchange with hot water in the heat exchange tubes. Although the device can realize extrusion granulation of the medicine raw materials, in the granulation process, the stirring effect among the raw material components is insufficient, so that the medicine effect content of the granulated medicine obtained by granulation is not uniform enough.
disclosure of Invention
The invention aims to provide a granular medicine extrusion granulation production device to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
The utility model provides a graininess medicine extrusion granulation apparatus for producing, includes the support frame, and fixed mounting has the agitator on the support frame, is connected with the rotating turret through the driving of agitator motor in the agitator, is equipped with the mixing mechanism who is used for mixxing the dispersion to the pharmaceutical raw materials on the rotating turret, the vertical extruding means that is fixed with in agitator bottom, the extruding means bottom is equipped with by drive motor driven cutting mechanism, be equipped with the collecting vat during extrusion pipe below, the inside dispersion mechanism that is equipped with of collecting vat.
As a modified scheme of the invention: mixing mechanism installs the rotation axis on the rotating turret including rotating, and the rotation axis lateral wall is evenly fixed with a plurality of stirring board, be equipped with on the scraper blade and be used for driving the rotation axis around drive shaft pivoted drive mechanism.
As a modified scheme of the invention: the transmission mechanism comprises a transmission gear coaxially fixed with the rotating shaft, and an inner rack meshed and matched with the transmission gear is fixed on the inner wall of the stirring barrel.
As a modified scheme of the invention: the rotating shaft side wall is fixed with a sleeve, a sliding column is arranged in the sleeve in a sliding mode, a limiting spring is fixed between the sliding column and the sleeve, and a scraper blade which is abutted to the inner wall of the stirring barrel is fixed to one end, far away from the sleeve, of the sliding column.
as a modified scheme of the invention: the extruding mechanism comprises an extruding pipe fixed at the bottom of the stirring barrel, a plurality of extruding holes are uniformly formed in the bottom of the extruding pipe, the driving shaft vertically extends into the extruding pipe, and spiral blades are fixed on the surface of the driving shaft.
As a modified scheme of the invention: the cutting mechanism comprises an incomplete gear which is in transmission connection with the transmission motor through a belt pulley mechanism, a scraper which is in sliding butt connection with the bottom surface of the extrusion pipe is installed on the supporting frame, and a spur rack which is matched with the incomplete gear in a meshing mode is fixed on the scraper.
As a modified scheme of the invention: the bottom of the scraper is fixed with a sleeve plate, a guide pillar fixed with the support frame penetrates through the sleeve plate, and a spring ring is fixed between the sleeve plate and the support frame.
As a modified scheme of the invention: the dispersion mechanism comprises a stirring frame which is driven by a dispersion motor and is rotatably installed in the collecting tank, an air heater facing the scraper is fixed on the side wall of the supporting frame, a net cover is installed on the side wall, away from the air heater, of the collecting tank in an embedded mode, and an air extractor communicated with the inlet end and the net cover is arranged on the supporting frame.
Compared with the prior art, the invention has the beneficial effects that:
According to the invention, the medicine raw materials are stirred and mixed in a rotating manner through the arranged mixing mechanism, so that the medicine raw materials of all components can be fully and uniformly stirred, the medicine obtained by extrusion granulation has full efficacy, the arranged extrusion mechanism is used for extruding the raw materials from the extrusion holes, the cutting mechanism is used for cutting and granulating the strip-shaped raw materials extruded from the extrusion holes, the arranged hot air machine is used for quickly drying the medicine, the granular medicine is quickly formed, and the arranged dispersing mechanism is used for promoting the volatilization of the water of the medicine, so that the forming efficiency is further improved.
Drawings
FIG. 1 is a schematic view of the internal structure of the present invention;
FIG. 2 is an enlarged view of portion A of FIG. 1;
FIG. 3 is an enlarged view of portion B of FIG. 1;
Fig. 4 is a schematic perspective view of an extruded tube according to the present invention.
In the figure: 1-supporting frame, 2-collecting tank, 3-air heater, 4-extruding pipe, 5-stirring barrel, 6-internal rack, 7-transmission gear, 8-rotating frame, 9-stirring motor, 10-driving shaft, 11-helical blade, 12-transmission motor, 13-mesh enclosure, 14-air extractor, 15-dispersing motor, 16-stirring frame, 17-limiting spring, 18-sliding column, 19-sleeve, 20-stirring plate, 21-incomplete gear, 22-belt pulley mechanism, 23-straight rack, 24-scraper, 25-guide column, 26-mesh enclosure, 27-spring ring, 28-scraper, 29-extruding hole and 30-rotating shaft.
Detailed Description
The technical scheme of the patent is further described in detail by combining the following specific embodiments:
Example 1
Referring to fig. 1-4, a granular drug extrusion granulation production device comprises a support frame 1, wherein a stirring barrel 5 is fixedly mounted on the support frame 1, a rotating frame 8 is connected in the stirring barrel 5 through a stirring motor 9 in a driving manner, a mixing mechanism for stirring and dispersing drug raw materials is arranged on the rotating frame 8, an extrusion mechanism is vertically fixed at the bottom of the stirring barrel 5, a cutting mechanism driven by a transmission motor 12 is arranged at the bottom of the extrusion mechanism, a collecting tank 2 is arranged below an extrusion pipe 4, and a dispersing mechanism is arranged inside the collecting tank 2.
The agitator 5 of this device is used for depositing the powder material raw materials, stirs the mixture through mixing mechanism for each drug component can the intensive mixing, later extrudes the drug material through extrusion mechanism, and the raw materials after the extrusion realizes the granulation shaping receiving cutting mechanism's cutting action.
Specifically, the mixing mechanism comprises a rotating shaft 30 rotatably mounted on the rotating frame 8, a plurality of stirring plates 20 are uniformly fixed on the side wall of the rotating shaft 30, and a transmission mechanism for driving the rotating shaft 30 to rotate around the driving shaft 10 is arranged on the scraping plate 28.
Stirring motor 9 drive rotation axis 30 is rotatory, and rotation axis 30 drives the turret 8 rotatory, and the turret 8 drives rotation axis 30 on it and rotates together with stirring board 20, realizes the rotatory mixed effect to 5 inside medicine raw materials of agitator, and drive mechanism includes the drive gear 7 with the coaxial fixed of rotation axis 30, and 5 inner walls of agitator are fixed with the internal tooth strip 6 with drive gear 7 meshing adaptation.
When the rotating frame 8 rotates, the transmission gear 7 on the rotating frame 8 rotates around the driving shaft 10, and under the meshing action of the internal rack 6, the transmission gear 7 drives the rotating shaft 30 coaxially fixed with the transmission gear to rotate, namely, the rotating shaft 30 revolves around the driving shaft 10 along with the rotation of the stirring plate 20, so that the stirring and dispersing effects on the medicine raw materials in the stirring barrel 5 are greatly improved.
In order to scrape off the medicine adhered to the inner wall of the stirring barrel 5 and realize the comprehensive mixing of the medicine raw materials, a sleeve 19 is fixed on the side wall of the rotating shaft 30, a sliding column 18 is installed in the sleeve 19 in a sliding mode, a limiting spring 17 is fixed between the sliding column 18 and the sleeve 19, and a scraper 28 which is abutted against the inner wall of the stirring barrel 5 is fixed at one end, far away from the sleeve 19, of the sliding column 18.
Through the setting, the rotatory in-process of rotation axis 30 drives sleeve 19 and rotates, and sleeve 19 drives traveller 18 and rotates under spacing spring 17's elastic traction effect, and scraper blade 28 is rotatory and carry out rotatory striking off to the medicine raw materials of agitator 5 inner wall this moment, realizes the intensive mixing of medicine raw materials.
Example 2
In order to facilitate the extrusion of the pharmaceutical raw materials and the subsequent cutting and granulation, on the basis of embodiment 1, the extrusion mechanism includes an extrusion tube 4 fixed at the bottom of the stirring barrel 5, a plurality of extrusion holes 29 are uniformly formed at the bottom of the extrusion tube 4, the driving shaft 10 vertically extends into the extrusion tube 4, and the surface of the driving shaft 10 is fixed with a helical blade 11.
The driving shaft 10 can drive the helical blade 11 to rotate and screw the medicine raw material in the stirring barrel 5 into the extrusion pipe 4, the medicine raw material is extruded out from the extrusion hole 29 and forms a strip-shaped structure, and the arranged cutting mechanism cuts the strip-shaped medicine into granules.
Specifically, the cutting mechanism comprises an incomplete gear 21 in transmission connection with the transmission motor 12 through a belt pulley mechanism 22, a scraper 24 in sliding abutting connection with the bottom surface of the extrusion pipe 4 is installed on the support frame 1, and a spur rack 23 in meshing fit with the incomplete gear 21 is fixed on the scraper 24.
The transmission motor 12 drives the incomplete gear 21 to rotate through the belt pulley mechanism 22, the incomplete gear 21 is intermittently meshed with the spur rack 23, a sleeve plate 26 is fixed at the bottom of the scraper 24, a guide post 25 fixed with the support frame 1 penetrates through the sleeve plate 26, a spring ring 27 is fixed between the sleeve plate 26 and the support frame 1, and in the process of intermittently meshing the incomplete gear 21 and the spur rack 23, the transverse reciprocating motion of the scraper 24 is realized through the elastic deformation of the spring ring 27, so that the repeated cutting and granulating actions of the strip-shaped medicines are realized.
Further, this device has still set up dispersion mechanism, includes and installs the stirring frame 16 in collecting vat 2 by dispersion motor 15 driven rotation, and 1 lateral wall of support frame is fixed with the air heater 3 towards scraper 24, and collecting vat 2 keeps away from the lateral wall of air heater 3 and inlays to establish and install screen panel 13, is equipped with the air extractor 14 of entrance point and screen panel 13 intercommunication on the support frame 1.
When scraper 24 is cutting the strip medicine of extruding from extruding hole 29, air heater 3 can carry out dry design effect to the medicine, promote the cutting shaping effect of medicine, the graininess medicine that the cutting obtained falls into to collection tank 2 inside, the rotatory dispersion that realizes the graininess medicine of dispersion motor 15 drive stirring frame 16, further promote volatilizing of moisture, realize quick design, the air of collection tank 2 inside is extracted to the air extractor 14 of setting, the hot-air that air heater 3 produced in time supplyes to collection tank 2 inside, the drying of medicine has further been promoted, avoid the bonding of granule medicine.
in summary, the mixing mechanism provided in the invention rotationally stirs and mixes the raw materials, so that the raw materials of each component can be fully and uniformly stirred, and the extrusion granulation is ensured to obtain the full drug effect of the drug, the extrusion mechanism provided in the invention realizes the extrusion of the raw materials from the extrusion holes 29, the cutting mechanism realizes the cutting granulation of the strip raw materials extruded from the extrusion holes 29, the hot air blower 3 provided in the invention realizes the rapid drying of the drug, the granular drug can be rapidly formed, and the dispersion mechanism provided in the invention promotes the volatilization of the moisture of the drug, and the forming efficiency is further improved.
Claims (8)
1. the utility model provides a graininess medicine extrusion granulation apparatus for producing, includes support frame (1), and fixed mounting has agitator (5) on support frame (1), its characterized in that, be connected with rotating turret (8) through agitator motor (9) drive in agitator (5), be equipped with on rotating turret (8) and be used for stirring the mixing mechanism of dispersion to the medicine raw materials, the vertical extruding means that is fixed with in agitator (5) bottom, the extruding means bottom is equipped with by driving motor (12) driven cutting mechanism, be equipped with collecting vat (2) during extrusion pipe (4) below, collecting vat (2) inside is equipped with dispersion mechanism.
2. The extrusion granulation production device of the granular drug according to claim 1, wherein the mixing mechanism comprises a rotating shaft (30) rotatably mounted on the rotating frame (8), a plurality of stirring plates (20) are uniformly fixed on the side wall of the rotating shaft (30), and the scraper (28) is provided with a transmission mechanism for driving the rotating shaft (30) to rotate around the driving shaft (10).
3. the extrusion granulation production device of the granular medicine according to claim 2, wherein the transmission mechanism comprises a transmission gear (7) coaxially fixed with the rotating shaft (30), and an internal rack (6) meshed and matched with the transmission gear (7) is fixed on the inner wall of the stirring barrel (5).
4. The extrusion granulation production device of the granular medicine according to claim 2, wherein a sleeve (19) is fixed on the side wall of the rotating shaft (30), a sliding column (18) is installed in the sleeve (19) in a sliding manner, a limiting spring (17) is fixed between the sliding column (18) and the sleeve (19), and a scraper (28) which is abutted against the inner wall of the stirring barrel (5) is fixed at one end, far away from the sleeve (19), of the sliding column (18).
5. The extrusion granulation production device for granular drugs according to claim 2, wherein the extrusion mechanism comprises an extrusion tube (4) fixed at the bottom of the stirring barrel (5), a plurality of extrusion holes (29) are uniformly formed at the bottom of the extrusion tube (4), the driving shaft (10) vertically extends into the extrusion tube (4), and the surface of the driving shaft (10) is fixed with a helical blade (11).
6. The extrusion granulation production device of the granular medicine according to claim 5, wherein the cutting mechanism comprises an incomplete gear (21) in transmission connection with the transmission motor (12) through a belt wheel mechanism (22), a scraper (24) in sliding contact with the bottom surface of the extrusion pipe (4) is installed on the support frame (1), and a spur rack (23) in meshing fit with the incomplete gear (21) is fixed on the scraper (24).
7. The extrusion granulation production device of granular drugs according to claim 6, wherein the bottom of the scraper (24) is fixed with a sleeve plate (26), the sleeve plate (26) is provided with a guide post (25) fixed with the support frame (1) in a penetrating way, and a spring ring (27) is fixed between the sleeve plate (26) and the support frame (1).
8. The extrusion granulation production device of granular drugs according to claim 6, wherein the dispersion mechanism comprises a stirring frame (16) rotatably mounted in the collection tank (2) by a dispersion motor (15), the side wall of the support frame (1) is fixed with a hot air blower (3) facing the scraper (24), the side wall of the collection tank (2) far away from the hot air blower (3) is embedded with a mesh enclosure (13), and the support frame (1) is provided with an air extractor (14) with an inlet end communicated with the mesh enclosure (13).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201910956097.6A CN110559187A (en) | 2019-10-09 | 2019-10-09 | Granular medicine extrusion granulation production device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910956097.6A CN110559187A (en) | 2019-10-09 | 2019-10-09 | Granular medicine extrusion granulation production device |
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| CN110559187A true CN110559187A (en) | 2019-12-13 |
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| CN201910956097.6A Pending CN110559187A (en) | 2019-10-09 | 2019-10-09 | Granular medicine extrusion granulation production device |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111840071A (en) * | 2020-07-31 | 2020-10-30 | 山东润德生物科技有限公司 | Production equipment of glucosamine ossein peptide calcium granules |
| CN113797096A (en) * | 2021-10-09 | 2021-12-17 | 宁波双伟制药有限公司 | Granular medicament making machine |
| CN114081157A (en) * | 2021-12-14 | 2022-02-25 | 吉安市中香天然植物有限公司 | Preparation method of granular essence and granulation device thereof |
| CN114345784A (en) * | 2021-12-30 | 2022-04-15 | 宜春万申制药机械有限公司 | Coating machine for Chinese and western medicine tablet surface treatment |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111840071A (en) * | 2020-07-31 | 2020-10-30 | 山东润德生物科技有限公司 | Production equipment of glucosamine ossein peptide calcium granules |
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| CN114081157A (en) * | 2021-12-14 | 2022-02-25 | 吉安市中香天然植物有限公司 | Preparation method of granular essence and granulation device thereof |
| CN114345784A (en) * | 2021-12-30 | 2022-04-15 | 宜春万申制药机械有限公司 | Coating machine for Chinese and western medicine tablet surface treatment |
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Application publication date: 20191213 |
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| RJ01 | Rejection of invention patent application after publication |