CN110551572A - Extraction method of cassia twig volatile oil - Google Patents
Extraction method of cassia twig volatile oil Download PDFInfo
- Publication number
- CN110551572A CN110551572A CN201810536425.2A CN201810536425A CN110551572A CN 110551572 A CN110551572 A CN 110551572A CN 201810536425 A CN201810536425 A CN 201810536425A CN 110551572 A CN110551572 A CN 110551572A
- Authority
- CN
- China
- Prior art keywords
- kettle
- extraction
- separation
- separation kettle
- cassia twig
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
- C11B1/104—Production of fats or fatty oils from raw materials by extracting using super critical gases or vapours
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/025—Recovery by solvent extraction
Abstract
The invention discloses an extraction method of cassia twig volatile oil, which comprises the following steps: drying and crushing cassia twig medicinal materials, and sieving the crushed cassia twig medicinal materials with a 18-mesh sieve. Drying at 60 deg.C for 4 hr, precisely weighing 100g (to 0.0001g), and placing into extraction kettle. Heating the extraction kettle, the separation kettle I and the separation kettle II, and pressurizing the system by a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 35-40 ℃. When the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 15-35MPa, the flow of CO2 is adjusted, and the constant temperature and the constant pressure are kept. And after the selected extraction time is reached, discharging from discharge ports of the separation kettle I and the separation kettle II, and respectively collecting and storing the extracts. Separating the extract with chromatography column. The extraction method of the invention is simple and easy to implement, has high yield, does not need a large amount of organic solvents, is safe and nontoxic, and is suitable for industrial production.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a method for extracting cassia twig volatile oil. Background
Ramulus Cinnamomi, also known as ramulus Cinnamomi, is the dry twig of Cinnamomum cassia of Lauraceae, produced mainly in Guangdong, Guangxi and Yunnan provinces. Collected in spring and summer, leaves are removed, and the product is dried in the sun or sliced and dried in the sun, unprocessed. The medicine property is pungent, sweet and warm; meridian tropism includes heart, lung and bladder; has effects in inducing sweat, expelling pathogenic factors from muscles, warming and activating channels, and supporting yang to regulate qi, and can be used for treating dyspepsia, gastritis, blood circulation disorder, and inflammatory diseases. Cassia twig has also been found to have antioxidant activity, inhibiting the synthesis of cyclooxygenase and nitric oxide.
One of the main effective substances of cassia twig is volatile oil, which mainly contains cinnamaldehyde, and in addition, contains all the components of phenols, organic acids, polysaccharides, glycosides, coumarins, tannins and the like. In recent years, a plurality of researchers deeply research the raw pharmaceutical and chemical components of the cassia twig, but the corresponding production process reports that the prior reported extraction methods of the cassia twig volatile oil comprise a supercritical CO2 extraction method and a conventional volatile oil extraction method (a steam distillation method), and the invention adopts the supercritical CO2 extraction method to extract the cassia twig volatile oil and aims at selecting a new method for industrially extracting the cassia twig volatile oil.
Disclosure of Invention
The invention aims to provide the extraction method of the cassia twig volatile oil, which has the advantages of safety, no toxicity, short time consumption, high extraction rate, simple process and continuous operation.
The invention comprises the following steps:
a. Drying and crushing cassia twig medicinal materials, and sieving the crushed cassia twig medicinal materials with a 18-mesh sieve.
b.60 ℃ drying for 4h, accurately weighing 100g (to the accuracy of 0.0001g), and placing into an extraction kettle.
c. and (3) extraction: heating the extraction kettle, the separation kettle I and the separation kettle II, and pressurizing the system by a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 35-40 ℃. When the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 15-35MPa, the flow of CO2 is adjusted, and the constant temperature and the constant pressure are kept. And after the selected extraction time is reached, discharging from the discharge holes of the separation kettle I and the separation kettle II, and respectively collecting and storing.
d. Extraction and separation: separating the extract with chromatography column.
The extraction method of the invention is simple and easy, does not need a large amount of organic solvent, is safe and nontoxic, and is suitable for industrial production.
The specific implementation mode is as follows:
The invention is illustrated below by way of example, without the protection of the invention being restricted thereto.
Example 1:
drying and crushing cassia twig medicinal materials, sieving the crushed cassia twig medicinal materials with a 18-mesh sieve, drying the cassia twig medicinal materials for 4 hours at 60 ℃, precisely weighing 100g (precisely 0.0001g) of the cassia twig medicinal materials, putting the cassia twig medicinal materials into an extraction kettle, heating the extraction kettle, a separation kettle I and a separation kettle II, pressurizing a system by a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 35 ℃, regulating the flow of CO 2 when the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 15MPa respectively, keeping constant temperature and constant pressure, discharging the materials from discharge holes of the separation kettle I and the separation kettle II after the selected extraction time is reached, respectively collecting and storing the materials, and passing the obtained extract through a chromatographic column to
Example 2:
Drying and crushing cassia twig medicinal materials, sieving the crushed cassia twig medicinal materials with a 18-mesh sieve, drying the cassia twig medicinal materials for 4 hours at 60 ℃, precisely weighing 100g (precisely 0.0001g) of the cassia twig medicinal materials, putting the cassia twig medicinal materials into an extraction kettle, heating the extraction kettle, a separation kettle I and a separation kettle II, pressurizing a system through a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 35 ℃, adjusting the flow of CO 2 when the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 25MPa respectively, keeping constant temperature and constant pressure, discharging the materials from discharge holes of the separation kettle I and the separation kettle II after the selected extraction time is reached, respectively collecting and storing the materials, and passing the obtained extract through a chromatographic column to.
Example 3:
Drying and crushing cassia twig medicinal materials, sieving the crushed cassia twig medicinal materials with a 18-mesh sieve, drying the cassia twig medicinal materials for 4 hours at 60 ℃, precisely weighing 100g (precisely 0.0001g) of the cassia twig medicinal materials, putting the cassia twig medicinal materials into an extraction kettle, heating the extraction kettle, a separation kettle I and a separation kettle II, pressurizing a system through a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 45 ℃, adjusting the flow of CO 2 when the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 25MPa respectively, keeping constant temperature and constant pressure, discharging the materials from discharge holes of the separation kettle I and the separation kettle II after the selected extraction time is reached, respectively collecting and storing the materials, and passing the obtained extract through a chromatographic column to.
Example 4:
drying and crushing cassia twig medicinal materials, sieving the crushed cassia twig medicinal materials with a 18-mesh sieve, drying the cassia twig medicinal materials for 4 hours at 60 ℃, precisely weighing 100g (precisely 0.0001g) of the cassia twig medicinal materials, putting the cassia twig medicinal materials into an extraction kettle, heating the extraction kettle, a separation kettle I and a separation kettle II, pressurizing a system through a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 45 ℃, adjusting the flow of CO 2 when the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 35MPa respectively, keeping constant temperature and constant pressure, discharging the materials from discharge holes of the separation kettle I and the separation kettle II after the selected extraction time is reached, respectively collecting and storing the materials, and passing the obtained extract through a chromatographic column to.
Claims (2)
1. the extraction method of the cassia twig volatile oil is characterized by comprising the following steps:
a. Drying and crushing cassia twig medicinal materials, and sieving the crushed cassia twig medicinal materials with a 18-mesh sieve.
b.60 ℃ drying for 4h, accurately weighing 100g (to the accuracy of 0.0001g), and placing into an extraction kettle.
c. and (3) extraction: heating the extraction kettle, the separation kettle I and the separation kettle II, and pressurizing the system by a high-pressure pump when the temperature of the extraction kettle, the separation kettle I and the separation kettle II reaches 35-40 ℃. When the pressure of the extraction kettle, the separation kettle I and the separation kettle II reaches 15-35MPa, the flow of CO2 is adjusted, and the constant temperature and the constant pressure are kept. And after the selected extraction time is reached, discharging from the discharge holes of the separation kettle I and the separation kettle II, and respectively collecting and storing.
d. Extraction and separation: separating the extract with chromatography column.
2. The method for extracting cassia twig volatile oil as claimed in claim 1, wherein the extraction and separation device in step d is a 20mm x 600mm chromatographic column with 100 ~ 200 mesh sand, and the developing solvent is methylcyclohexane and ethyl acetate (5: 1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810536425.2A CN110551572A (en) | 2018-05-30 | 2018-05-30 | Extraction method of cassia twig volatile oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810536425.2A CN110551572A (en) | 2018-05-30 | 2018-05-30 | Extraction method of cassia twig volatile oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110551572A true CN110551572A (en) | 2019-12-10 |
Family
ID=68734169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810536425.2A Pending CN110551572A (en) | 2018-05-30 | 2018-05-30 | Extraction method of cassia twig volatile oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110551572A (en) |
-
2018
- 2018-05-30 CN CN201810536425.2A patent/CN110551572A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101259247B (en) | Method for continuously extracting various active ingredient in turmeric | |
| CN103006724A (en) | Andrographis paniculata extract and method for preparing same | |
| CN104666427A (en) | Method for extracting main active components of folium mori | |
| CN111848358A (en) | Method for preparing high-purity cannabidiol by combining macroporous resin enrichment with dynamic axial compression column system | |
| CN102031116A (en) | New method for preparing rosemary natural antioxidant | |
| CN102040612A (en) | Method for extracting bergamottin from grapefruit peel | |
| CN106038821A (en) | Method for extracting total flavonoids from boxthorn leaves | |
| CN109810789A (en) | A kind of extracting method of ginkgo essential oil | |
| CN110551572A (en) | Extraction method of cassia twig volatile oil | |
| CN110786513A (en) | Method for extracting and purifying hemp full spectrum oil | |
| CN103288900A (en) | Icariin preparation process flow | |
| CN102648965A (en) | Industrialization preparation method of lophatherum gracile general flavone | |
| CN111166842A (en) | Method for efficiently preparing kaempferia galanga extract | |
| CN108126000A (en) | Arasaponin extracts preparation method in fresh Radix Notoginseng | |
| CN112386616A (en) | Extraction method of red algae extract | |
| CN103408522A (en) | Method for extracting high-purity aesculetin from euphorbia lathyris fruit | |
| CN102936242A (en) | Method for comprehensively utilizing arrowroot | |
| CN102302531A (en) | Preparation method of gnaphalium affine total flavonoid | |
| CN101974008A (en) | Process for extracting and purifying podophyllotoxin from Dysosma difformis | |
| CN110841019A (en) | Preparation method of kaempferia galanga extract by using flavone as index | |
| CN111187669A (en) | Extraction method of magnolia flower volatile oil | |
| CN104447648A (en) | Method for preparing senkyunolide A from ligusticum wallichii medicine employing supercritical CO2 fluid | |
| CN104906201A (en) | Bitter buckwheat bran total flavonoid preparing method | |
| CN105079530B (en) | Method for separating and purifying flavone and lactone from bamboo leaves based on microwave-assisted process | |
| CN102344854A (en) | Method for extracting volatile oil from cynoglossum lanceolatum |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20191210 |
|
| WD01 | Invention patent application deemed withdrawn after publication |