CN110548462A - Reverse gelation oil core microcapsule based on alginate - Google Patents
Reverse gelation oil core microcapsule based on alginate Download PDFInfo
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Abstract
The invention discloses an alginate-based reverse gelation oil core microcapsule, which comprises the following preparation steps: adding 1L of vegetable oil and 0.1-20 g of surfactant into a reaction kettle, stirring at a high speed, uniformly mixing, adding 20-40 mL of tricalcium phosphate solution, and stirring at a high speed to obtain an emulsion; slowly adding 20mL of emulsion into 1-3L of alginate solution, and stirring for 2-10 min to disperse the emulsion in the alginate solution; and sequentially adding 15-30 mL of polyoxyethylene sorbitan monolaurate and 100-200 mL of ethanol into the dispersion to form the microcapsule. The microcapsule is prepared by the reverse gel technology, the high embedding rate of oil can be realized, the wall material thickness is uniform, the oil embedding rate reaches more than 95%, the size of the microcapsule is controllable, the preparation process is simple, the microcapsule is green and environment-friendly, and the prepared microcapsule can be applied to the fields of cosmetics, biological medicines, foods and the like.
Description
Technical Field
The invention relates to a divisional application of a Chinese patent 'alginate reverse gelation-based oil core microcapsule and a preparation method thereof', wherein the application date is 7 months and 20 days in 2017, and the application number is 201710596456.2. The invention relates to the technical field of microcapsule preparation, in particular to an alginate-based reverse gelation oil core microcapsule and a preparation method thereof.
Background
The microcapsule is generally spherical and is a micro-container mainly prepared from artificial or natural high molecular materials by different preparation methods. The various techniques of microcapsules begin in the 30 th of the 20 th century, but are regarded and developed rapidly in the middle and later stages of the 20 th century. The microcapsules themselves have many advantages, such as shielding against color, odor, protecting the embedding from environmental damage, changing the volume, mass or surface properties of the substance, controlling the release properties of the embedding (core material), etc.
The microcapsule consists of a wall material and a wall core, the embedded substance is called a core material, and the core material can be an oil-soluble or water-soluble compound or a mixture and can be in a powder, solid, liquid or gas state; the substance embedding the core material is called wall material, and the wall material can be used as microcapsule encapsulating material and comprises natural polymer, semisynthetic polymer and synthetic polymer material. The alginate is a natural microcapsule wall material, has the characteristics of low immunogenicity, good biocompatibility, degradability, no toxic or side effect of a product, low price and the like, and is the most common material for preparing bioactive microcapsules. The oil is widely applied to formulas in the fields of food, medicine, cosmetics and the like due to the medicinal value and the nutritional value, but the oil can be oxidized in the presence of light, heat, metal ions or oxygen, and the microcapsule can solve the problem to a certain extent.
At present, the production process methods of the microcapsules mainly comprise a centrifugal extrusion method, a spray drying method, an interfacial polymerization method and a gel method. Spray drying is the most economical and common method for embedding oil, but the spraying process is carried out at high temperature (around 160 ℃), which accelerates the oxidation of the embedding, such as cn201010193794. x. The centrifugal extrusion method requires a complicated extrusion apparatus and has a low productivity, such as CN 201110183304.2. Although the yield is high, the interfacial polymerization method requires the acid and alkali resistance of the embedded object, for example, CN200310111493 is an emulsification method using interfacial polymerization, and water is used as a solvent, an aqueous solution of carboxymethyl chitosan and sodium alginate is blended, then bovine serum albumin is dissolved and dispersed in liquid paraffin, and then CaCl2 and isopropanol are dripped. The gel method is divided into a single gel method and a complex gel method, the single gel method uses a high molecular wall material, embedding substances are dispersed in the high molecular wall material, and then coagulant is added, and the solubility of the wall material is reduced and the wall material is coagulated into microcapsules due to the combination of a large amount of moisture and the coagulant, so that the microcapsules prepared by the method have larger grain diameter and higher production cost; the double gel method is to use two substances with opposite charges as wall materials, embedding substances are dispersed in the wall materials, the two wall materials are condensed into microcapsules to be precipitated due to the reduction of solubility under the action of charges by changing the pH value, the temperature or the solution concentration, and the formation and precipitation processes of the microcapsules are greatly influenced by the three conditions of the temperature, the pH value and the concentration, so that the reaction conditions are difficult to control, the maximum yield can be obtained only when the charges of the two substances are equal, chemical substances (such as sebacoyl chloride) except basic raw materials are required to be added in the production process, the production cost is high, and the microcapsules with small sizes are difficult to obtain. For example, CN201310246216 is prepared by assembling alginate and lysozyme with opposite charges alternately on the surface of microcapsule by electrospray and double gel method.
From the above analysis, although there are many methods for manufacturing microcapsules at present, each process flow has disadvantages in the manufacturing process, such as high temperature is required, some production equipment is complicated, some production efficiency is low, some have special requirements for the production environment temperature, and some capsule sizes of the production line do not meet the requirements. And the size of the microcapsule prepared by the preparation methods is not controllable.
Disclosure of Invention
In view of the problems in the prior art, the present invention provides an alginate-based reverse-gelling oil core microcapsule and a preparation method thereof, wherein the preparation method has the advantages of controllable size, high oil embedding rate, suitability for the conditions and the characteristics, low cost and high productivity.
In order to achieve the purpose, the invention is realized by the following technical scheme:
The alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is alginate, and the wall core is vegetable oil, and comprises the following components in parts by weight:
A preparation method of an alginate-based reverse gelation oil core microcapsule comprises the following steps:
(1) Preparation of an emulsion: adding 1L of vegetable oil and 0.1-20 g of surfactant into a reaction kettle, stirring at a high speed, shearing, uniformly mixing, then slowly adding 20-40 mL of tricalcium phosphate solution, and stirring at a high speed and shearing;
(2) Dispersion of the emulsion in the alginate solution: slowly adding 20mL of emulsion into 1-3L of alginate solution, and stirring for 2-10 min to disperse the water-in-oil emulsion in the alginate solution;
(3) And (3) forming a microcapsule: and (3) sequentially adding 15-30 mL of polyoxyethylene sorbitan monolaurate and 100-200 mL of ethanol into the solution in the step (2) to form microcapsules in the solution.
The alginate is at least one of potassium alginate, sodium alginate, zinc alginate and barium alginate.
the vegetable oil is at least one of sunflower seed oil, sesame oil and soybean oil.
the surfactant is at least one of polyglycerol ricinoleate and sorbitan trioleate.
After 1L of vegetable oil and 0.1-20 g of surfactant are added into the reaction kettle, the high-speed stirring shearing speed is 10000-20000 rpm, and the high-speed stirring shearing time is 1-3 min.
After the tricalcium phosphate solution is added, the high-speed stirring and shearing speed is 10000-20000 rpm, and the high-speed stirring and shearing time is 3-10 min.
The stirring speed in the step (2) is 100-500 rpm.
The steps are carried out at 20-80 ℃.
The emulsion is water-in-oil emulsion.
The microcapsule is oil core and alginate film, and there is gap between the core and the film.
The particle size of the microcapsule is 300-550 microns, and the film thickness is 30-200 microns.
The innovation of the invention is that a reverse gel method is adopted, the traditional sol-gel method that alginate solution is prepared firstly and then CaCl2 is dripped is changed, the emulsion of oil and tricalcium phosphate solution is dripped into alginate salt bath, Ca2+ ions are diffused to the periphery of liquid drops, and the liquid drops are crosslinked with alginate polymer at a dripping interface. Because the size of the microcapsule determines the degree of oxidation of the embedding substance and the release performance of the embedding substance, different application fields have different requirements on the size of the microcapsule. In the prior art, although the centrifugal extrusion method, the spray drying method, the interfacial polymerization method and the gel method can control the size of the microcapsule through vibration, a nozzle and other means, the size of the prepared oil core microgel is difficult to regulate and control, the embedding rate of oil is lower than 10 percent, and the oil which is not embedded can not be recovered after the process is finished, so that the utilization rate of the oil is low. In addition, the traditional method has the defects that the prepared capsule has larger grain diameter or larger dispersity of grain diameter distribution, or the influence on thermosensitive materials is caused by high temperature, or the balance system of emulsion is easily damaged, so that the microcapsules are agglomerated together to form large-scale gel.
The beneficial effects of the invention include:
(1) the preparation method of the oil-core alginate microcapsule by using the reverse gel method of alginate and using water-in-oil emulsion as a template and a very simple device has no release of hydrophobic substances, is suitable for the situation that active substances or volatile compounds need to be reserved for a long time, and can be applied to the fields of cosmetics, biomedicine, food, agriculture and the like.
(2) The size of the oil-core alginate microcapsule prepared by the method is controllable, the stirring speed of the emulsion in the alginate solution is controlled to control the microcapsule to be 300-550 microns, and the size of the microcapsule can also be controlled by the adding amount of polyoxyethylene sorbitan monolaurate and ethanol.
(3) the invention realizes high oil embedding rate, the oil embedding rate reaches more than 95 percent, the wall material (film) has uniform thickness, the microcapsule is stable, and the stabilization time is long.
(4) Nontoxic reagents and solvents are used in the preparation process.
(5) The reverse gel method for preparing the oil-core alginate microcapsules is less influenced by temperature, can be carried out at room temperature, and is suitable for temperature-sensitive active substances.
Detailed Description
The present invention will be further described with reference to examples, but the present invention is not limited to these examples.
example 1
The alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is sodium alginate, and the wall core is sunflower seed oil, and comprises the following components in parts by weight: 10-30 parts of sodium alginate; 10 parts of sunflower seed oil; 0.0001-0.02 part of polyglycerol ricinoleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) preparing a water-in-oil emulsion: adding 1L sunflower seed oil and 0.1g polyglycerol ricinoleate into a reaction kettle, stirring and shearing at a high speed of 10000rpm for 1min, then slowly adding 20mL tricalcium phosphate solution (20g/L), and stirring and shearing at a high speed of 10000rpm for 3 min.
(2) Dispersion of emulsion in sodium alginate solution: 20mL of the water-in-oil emulsion was slowly added to 1L of the sodium alginate solution, and stirred at 500rpm for 2min to disperse the water-in-oil emulsion in the sodium alginate solution.
(3) And (3) forming a microcapsule: and (3) adding 15mL of polyoxyethylene sorbitan monolaurate and 100mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
the three steps are carried out at 20 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 300 microns, a core diameter of about 250mm, and a membrane thickness of about 30 microns.
Example 2
The alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is potassium alginate, and the wall core is sunflower seed oil, and comprises the following components in parts by weight: 10-30 parts of potassium alginate; 10 parts of sunflower seed oil; 0.0001-0.02 part of polyglycerol ricinoleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) Preparing a water-in-oil emulsion: 1L of sunflower seed oil and 5g of polyglycerol ricinoleate are added into a reaction kettle, stirred and sheared at a high speed of 15000rpm for 2min, then 30mL of tricalcium phosphate solution (20g/L) is slowly added, and stirred and sheared at a high speed of 15000rpm for 6 min.
(2) dispersion of emulsion in potassium alginate solution: 20mL of the water-in-oil emulsion was slowly added to 2L of the potassium alginate solution and stirred at 400rpm for 6min to disperse the water-in-oil emulsion in the potassium alginate solution.
(3) And (3) forming a microcapsule: and (3) adding 20mL of polyoxyethylene sorbitan monolaurate and 150mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
The three steps are carried out at 40 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 360 microns, a core diameter of about 270mm and a membrane thickness of about 70 microns.
Example 3
The alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is barium alginate, and the wall core is sesame oil, and comprises the following components in parts by weight: 10-30 parts of barium alginate; 10 parts of sesame oil; 0.0001-0.02 part of polyglycerol ricinoleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) Preparing a water-in-oil emulsion: 1L of sesame oil and 10g of polyglycerol ricinoleate are added into a reaction kettle, stirred and sheared at a high speed of 20000rpm for 3min, then 40mL of tricalcium phosphate solution (20g/L) is slowly added, and stirred and sheared at a high speed of 20000rpm for 10 min.
(2) Dispersion of emulsion in barium alginate solution: 20mL of the water-in-oil emulsion was slowly added to 3L of the barium alginate solution, and stirred at 300rpm for 10min to disperse the water-in-oil emulsion in the barium alginate solution.
(3) And (3) forming a microcapsule: and (3) adding 25mL of polyoxyethylene sorbitan monolaurate and 150mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
the three steps are carried out at 60 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 400 microns, a core diameter of about 280mm and a film thickness of about 100 microns.
Example 4
the alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is zinc alginate, and the wall core is sunflower seed oil, and comprises the following components in parts by weight: 10-30 parts of zinc alginate; 10 parts of sunflower seed oil; 0.0001-0.02 part of polyglycerol ricinoleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) Preparing a water-in-oil emulsion: 1L of sunflower seed oil and 20g of polyglycerol ricinoleate are added into a reaction kettle, stirred and sheared at high speed of 18000rpm for 3min, then 20mL of tricalcium phosphate solution (20g/L) is slowly added, and stirred and sheared at high speed of 18000rpm for 10 min.
(2) dispersion of the emulsion in the zinc alginate solution: 30mL of the water-in-oil emulsion was slowly added to 1L of the zinc alginate solution and stirred at 200rpm for 4min to disperse the water-in-oil emulsion in the zinc alginate solution.
(3) And (3) forming a microcapsule: and (3) adding 30mL of polyoxyethylene sorbitan monolaurate and 200mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
the three steps are carried out at 60 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 470 microns, an inner core diameter of about 300mm, and a membrane thickness of about 150 microns.
Example 5
The alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is sodium alginate, and the wall core is soybean oil, and comprises the following components in parts by weight: 10-30 parts of sodium alginate; 10 parts of soybean oil; 0.0001-0.02 part of polyglycerol ricinoleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) Preparing a water-in-oil emulsion: 1L of soybean oil and 15g of polyglycerol ricinoleate are added into a reaction kettle, stirred and sheared at a high speed of 20000rpm for 3min, then 25mL of tricalcium phosphate solution (20g/L) is slowly added, and stirred and sheared at a high speed of 20000rpm for 10 min.
(2) Dispersion of emulsion in sodium alginate solution: 20mL of the water-in-oil emulsion was slowly added to 1L of the sodium alginate solution, and stirred at 100rpm for 2min to disperse the water-in-oil emulsion in the sodium alginate solution.
(3) and (3) forming a microcapsule: and (3) adding 30mL of polyoxyethylene sorbitan monolaurate and 200mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
The three steps are carried out at 60 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 550 microns, an inner core diameter of about 330mm, and a membrane thickness of about 200 microns.
Example 6
the alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is zinc alginate, and the wall core is soybean oil, and comprises the following components in parts by weight: 10-30 parts of zinc alginate; 10 parts of soybean oil; 0.0001-0.02 part of sorbitan trioleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) preparing a water-in-oil emulsion: 1L of soybean oil and 0.1g of sorbitan trioleate are added into a reaction kettle, stirred and sheared at a high speed of 15000rpm for 2min, then 40mL of tricalcium phosphate solution (20g/L) is slowly added, and stirred and sheared at a high speed of 15000rpm for 6 min.
(2) Dispersion of the emulsion in the zinc alginate solution: 25mL of the water-in-oil emulsion was slowly added to 1L of the zinc alginate solution and stirred at 100rpm for 8min to disperse the water-in-oil emulsion in the zinc alginate solution.
(3) And (3) forming a microcapsule: and (3) adding 30mL of polyoxyethylene sorbitan monolaurate and 200mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
the three steps are carried out at 60 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 520 microns, a core diameter of about 320mm, and a membrane thickness of about 180 microns.
example 7
the alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is sodium alginate, and the wall core is soybean oil, and comprises the following components in parts by weight: 10-30 parts of sodium alginate; 10 parts of soybean oil; 0.0001-0.02 part of sorbitan trioleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) Preparing a water-in-oil emulsion: adding 1L of soybean oil and 10g of sorbitan trioleate into a reaction kettle, stirring and shearing at a high speed of 10000rpm for 1min, then slowly adding 20mL of tricalcium phosphate solution (20g/L), and stirring and shearing at a high speed of 10000rpm for 4 min.
(2) Dispersion of emulsion in sodium alginate solution: the water-in-oil emulsion was dispersed in the sodium alginate solution by slowly adding 25mL of the water-in-oil emulsion to 2L of the sodium alginate solution and stirring at 200rpm for 10 min.
(3) And (3) forming a microcapsule: and (3) adding 15mL of polyoxyethylene sorbitan monolaurate and 150mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
The three steps are carried out at 80 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 480 microns, a core diameter of about 290mm, and a membrane thickness of about 180 microns.
Example 8
The alginate-based reverse gelation oil core microcapsule consists of a wall material and a wall core, wherein the wall material is potassium alginate, and the wall core is sesame oil, and comprises the following components in parts by weight: 10-30 parts of potassium alginate; 10 parts of sesame oil; 0.0001-0.02 part of sorbitan trioleate; 0.015-0.03 part of polyoxyethylene sorbitan monolaurate. The preparation method comprises the following steps:
(1) preparing a water-in-oil emulsion: adding 1L of sesame oil and 20g of sorbitan trioleate into a reaction kettle, stirring and shearing at a high speed of 10000rpm for 3min, then slowly adding 35mL of tricalcium phosphate solution (20g/L), and stirring and shearing at a high speed of 10000rpm for 10 min.
(2) dispersion of emulsion in potassium alginate solution: 25mL of the water-in-oil emulsion was slowly added to 3L of the potassium alginate solution, and stirred at 500rpm for 5min to disperse the water-in-oil emulsion in the potassium alginate solution.
(3) And (3) forming a microcapsule: adding 25mL of polyoxyethylene sorbitan monolaurate and 100mL of ethanol into the solution in the step (2) in sequence to form microcapsules in the solution.
The three steps are carried out at 50 ℃, the prepared microcapsule is an oil core and an alginate membrane, and a gap exists between the core and the membrane. The microcapsules had a particle size of about 330 microns, an inner core diameter of about 270mm and a membrane thickness of about 50 microns.
Claims (10)
1. The alginate-based reverse gelation oil core microcapsule is composed of a wall material and a wall core, and is characterized in that the wall material is alginate, and the wall core is vegetable oil, and comprises the following components in parts by weight:
The microcapsule is an oil core and an alginate film, a gap exists between the core and the film, the particle size is 300-550 micrometers, and the film thickness is 30-200 micrometers.
2. The alginate-based reverse gelling oil core microcapsule according to claim 1, wherein the alginate is at least one of potassium alginate, sodium alginate, zinc alginate, and barium alginate; the surfactant is at least one of polyglycerol ricinoleate and sorbitan trioleate; the vegetable oil is at least one of sunflower seed oil, sesame oil and soybean oil.
3. The alginate reverse-gelling oil core microcapsule according to claim 1 or 2, wherein the preparation is carried out by adding an emulsion of vegetable oil and tricalcium phosphate solution dropwise to the alginate bath, diffusing Ca2+ ions to the periphery of the droplets and cross-linking the alginate polymer at the interface of the droplets.
4. The alginate reverse gelation oil core based microcapsule according to claim 1 or 2, wherein the preparation method comprises the following steps:
(1) Preparation of an emulsion: adding 1L of vegetable oil and 0.1-20 g of surfactant into a reaction kettle, stirring at a high speed, shearing, uniformly mixing, then slowly adding 20-40 mL of tricalcium phosphate solution, and stirring at a high speed and shearing;
(2) Dispersion of the emulsion in the alginate solution: slowly adding 20mL of emulsion into 1-3L of alginate solution, and stirring for 2-10 min to disperse the emulsion in the alginate solution;
(3) and (3) forming a microcapsule: and (3) sequentially adding 15-30 mL of polyoxyethylene sorbitan monolaurate and 100-200 mL of ethanol into the solution in the step (2) to form microcapsules in the solution.
5. The alginate reverse-gelling oil-core microcapsule according to claim 4, wherein the emulsion is a water-in-oil emulsion; the steps are all carried out at 20-80 ℃.
6. The alginate reverse gelation-based oil core microcapsule according to claim 4, wherein the high speed stirring shear rate after adding 1L of vegetable oil and 0.1-20 g of surfactant in the reaction kettle is 10000-20000 rpm, and the high speed stirring shear time is 1-3 min; after the tricalcium phosphate solution is added, the high-speed stirring and shearing speed is 10000-20000 rpm, and the high-speed stirring and shearing time is 3-10 min.
7. The alginate reverse gelation oil core microcapsule according to claim 4, wherein the stirring speed of step (2) is 100-500 rpm.
8. The potassium alginate-based reverse gelation oil core microcapsule is composed of a wall material and a wall core, and is characterized in that the wall material is potassium alginate, and the wall core is vegetable oil, and comprises the following components in parts by weight:
The vegetable oil is at least one of sunflower seed oil, sesame oil and soybean oil;
The surfactant is at least one of polyglycerol ricinoleate and sorbitan trioleate;
the microcapsule is an oil core and a potassium alginate film, a gap exists between the core and the film, the particle size is 300-550 micrometers, the film thickness is 30-200 micrometers, and the oil embedding rate is larger than or equal to 95%.
9. the zinc alginate-based reverse gelation oil core microcapsule is composed of a wall material and a wall core, and is characterized in that the wall material is zinc alginate, the wall core is vegetable oil, and the microcapsule comprises the following components in parts by weight:
the vegetable oil is at least one of sunflower seed oil, sesame oil and soybean oil;
The surfactant is at least one of polyglycerol ricinoleate and sorbitan trioleate;
The microcapsule is an oil core and a zinc alginate film, a gap exists between the core and the film, the particle size is 300-550 micrometers, the film thickness is 30-200 micrometers, and the oil embedding rate is larger than or equal to 95%.
10. The barium alginate-based reverse gelation oil core microcapsule is composed of a wall material and a wall core, and is characterized in that the wall material is barium alginate, the wall core is vegetable oil, and the microcapsule comprises the following components in parts by weight:
the vegetable oil is at least one of sunflower seed oil, sesame oil and soybean oil;
The surfactant is at least one of polyglycerol ricinoleate and sorbitan trioleate;
The microcapsule is an oil core and a barium alginate film, a gap exists between the core and the film, the particle size is 300-550 micrometers, the film thickness is 30-200 micrometers, and the oil embedding rate is larger than or equal to 95%.
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| CN107224946B (en) | 2019-12-31 |
| CN107224946A (en) | 2017-10-03 |
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