CN110547915A - sanitary cotton product using probiotics and preparation method thereof - Google Patents

sanitary cotton product using probiotics and preparation method thereof Download PDF

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Publication number
CN110547915A
CN110547915A CN201910809151.4A CN201910809151A CN110547915A CN 110547915 A CN110547915 A CN 110547915A CN 201910809151 A CN201910809151 A CN 201910809151A CN 110547915 A CN110547915 A CN 110547915A
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CN
China
Prior art keywords
probiotics
sanitary
sanitary napkin
lactobacillus
inactivated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910809151.4A
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Chinese (zh)
Inventor
张志全
李鹏先
杨益通
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YUNNAN BAIYAO QINGYITANG INDUSTRY Co Ltd
Original Assignee
YUNNAN BAIYAO QINGYITANG INDUSTRY Co Ltd
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Publication date
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Priority to CN201910809151.4A priority Critical patent/CN110547915A/en
Publication of CN110547915A publication Critical patent/CN110547915A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/15577Apparatus or processes for manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/20Tampons, e.g. catamenial tampons; Accessories therefor
    • A61F13/2002Tampons, e.g. catamenial tampons; Accessories therefor characterised by the use
    • A61F13/202Catamenial tampons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/45Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the shape
    • A61F13/47Sanitary towels, incontinence pads or napkins
    • A61F13/472Sanitary towels, incontinence pads or napkins specially adapted for female use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84Accessories, not otherwise provided for, for absorbent pads
    • A61F13/8405Additives, e.g. for odour, disinfectant or pH control

Abstract

A sanitary cotton product applying probiotics and a preparation method thereof relate to a nursing product for female menstrual period, in particular to a sanitary cotton product. The invention applies the sanitary cotton product of probiotics, and utilizes the coating technology to coat the inactivated probiotics or metabolite bacteria powder on the sanitary cotton product, when in use, the probiotics can be released into human body, thereby generating the effect of maintaining the balance of environmental flora in menstrual period.

Description

Sanitary cotton product using probiotics and preparation method thereof
Technical Field
The invention relates to a female menstrual period nursing article, in particular to a sanitary cotton product.
Background
The sanitary napkin is a nursing article for women in menstrual period, and mainly has the functions of absorbing moisture and preventing leakage. With the development of science and technology and the improvement of the sanitary level and requirements, the sanitary napkin has further improvement and expansion.
Chinese patent CN201410265665.5 proposes a sanitary napkin, the facing layer contains probiotic components, which can inhibit the growth of harmful bacteria. The vaginal pH buffer is designed by adopting the principle that lactic acid can maintain a weak acid environment in vagina and the pH buffer range is 3-8. When a human body suffers from inflammation, the pH value can reach 7.3 at most, and the pH value of the vagina is not lower than 3.5 under the general condition. The pH value of menstrual blood in menstrual period can reach 7.4 at most, and the sanitary towel buffer system added with probiotics can ensure that the pH value of private parts in menstrual period can be kept between 3.5 and 4.5, thereby effectively preventing a large amount of pathogenic bacteria in menstrual period from breeding and effectively reducing the risk of menstrual inflammation.
However, the above sanitary napkins use non-inactivated probiotics, and the environmental requirements for each production link are very high for the non-inactivated probiotics, so that the produced products can meet the relevant national regulations. However, the production process is harsh, which tends to increase the production cost. Furthermore, in use, non-inactivated probiotics are not safe to use, especially for people with immune deficiencies.
Chinese patent application 201610579583.7, publication No. CN105997840A, proposes an application of inactivated probiotics in nursing products, suspension and probiotic non-woven fabric, and describes that inactivated functional probiotics are sprayed on various nursing products for use, wherein the inactivated functional probiotics are one or more of lactobacillus acidophilus, lactobacillus bulgaricus, lactobacillus paracasei, lactobacillus fermentum, lactobacillus rhamnosus, bifidobacterium bifidum and bifidobacterium longum. The same probiotics as those used in the above patent, but it was found that the safety was not high enough, especially for people with allergic constitution.
Disclosure of Invention
the invention applies the sanitary cotton product of probiotics, utilizes the coating technology to coat the inactivated probiotics or metabolite bacteria powder on the sanitary cotton product, and when in use, the probiotics can be released into a human body, thereby generating the effect of maintaining the balance of environmental flora in menstrual period.
the sanitary cotton product using probiotics is prepared by coating the inactivated probiotics liquid or metabolite thereof on the sanitary cotton product.
The sanitary cotton product is a sanitary towel or a sanitary cotton strip, and the sanitary cotton strip is made of absorbable sanitary cotton fibers and non-woven fabrics and is processed into a strip shape and built-in; the sanitary towel is made of absorbent sanitary cotton, and is processed into sheet together with non-woven fabric, air-permeable basement membrane, etc., and is for external use.
the sanitary cotton product is characterized in that a non-woven fabric is covered outside a cotton core substrate, and a degradable polylactic acid (PLA) fiber material is preferably adopted as the non-woven fabric.
The probiotic liquid is prepared by adding inactivated probiotic powder or metabolite into dipotassium glycyrrhizinate, and adding water to prepare aqueous solution, wherein the probiotic powder accounts for 0.5% and the dipotassium glycyrrhizinate accounts for 1% by weight; wherein the inactivated probiotics is one or a combination of lactobacillus salivarius and lactobacillus plantarum, and is obtained after inactivation, and the coating weight of the inactivated probiotics is 10-30 gsm.
The sanitary napkin added with probiotics is probiotic dead bacteria or metabolites of the probiotics obtained after irradiation sterilization, has no life activity, but the inactivated probiotics or the metabolites can still maintain the biological functions of the live probiotics, and the specific expression is as follows:
(1) The inactivated probiotics or metabolites contain a large amount of bacteriocins, lactic acid, and other metabolites, which can promote flora balance;
(2) Inactivation of cell walls in probiotics or metabolites, and the metabolites can help regulate the immune system;
(3) The thallus DNA in the inactivated probiotics can also relieve inflammatory reaction;
(4) The inactivated probiotics still contain a certain amount of lactic acid, and the pH value can be adjusted after the lactic acid is released.
compared with the use of inactivated probiotics, the invention uses the inactivated probiotics or metabolites, so that the invention has more use and production safety and is more convenient for large-scale production, and the concrete expression is as follows:
(1) can regulate immune system through cell debris and surface receptor;
(2) Contains lactic acid, reduces pH, and inhibits other bacteria from growing;
(3) Contains antibacterial substances such as bacteriocin, etc., and can promote microecological balance;
(4) more processing technologies are met;
(5) For products with limited microorganisms, the requirement on production compliance is more easily met;
(6) The shelf life is longer, and the performance is more stable;
(7) It is safe for people with immunodeficiency.
Detailed Description
example 1: the tampon using probiotics is prepared by the following steps:
S1: selecting any one of lactobacillus salivarius and lactobacillus plantarum, inactivating by irradiation, and drying to prepare probiotic powder;
s2: adding dipotassium glycyrrhizinate into probiotic powder, and adding water to prepare an aqueous solution for later use, wherein the probiotic powder accounts for 0.5 percent and the dipotassium glycyrrhizinate accounts for 1 percent by weight;
s3: preparing a tampon;
s4: coating a degradable polylactic acid fiber hot-rolled non-woven fabric layer PLA outside the tampon;
And S5, rolling and coating the probiotic water solution obtained in the step S2 on non-woven fabric, wherein the liquid applying amount is 10gsm, and quickly drying, packaging and warehousing.
The probiotic is added to keep the vagina in a weak acid environment, so that the bacteria are prevented from breeding and inflammation is caused, particularly in menstrual period. The vagina itself contains more than 50 bacteria, and the normal acidic environment is maintained by these lactobacilli. The genus Lactobacillus consists of a group of bacilliform lactic acid bacteria with various genetic and physiological characteristics, and the species of this genus can be divided into 3 groups, i.e., homolactic-fermented Lactobacillus, facultative heterolactic-fermented Lactobacillus, and obligate heterolactic-fermented Lactobacillus.
Homolactic fermentive lactobacilli include Lactobacillus delbrueckii subsp bulgaricus, Lactobacillus delbrueckii subsp lactis, Lactobacillus helveticus, etc., and they grow at high temperature (>45 ℃) and belong to thermophilic microorganisms, as compared with the lactobacilli of the other two groups. Another species of this group is lactobacillus acidophilus.
The lactobacillus for facultative heterotypic lactic fermentation is lactobacillus casei, and is commonly used for producing fermented dairy products by probiotics.
A typical representative of obligate heterolactic fermentive lactobacillus is lactobacillus caucasianus, a species often associated with kefir starter production.
The above mentioned species are selected as probiotics for a sanitary napkin proposed in chinese patent CN 201410265665.5. Such as: lactobacillus acidophilus, lactobacillus bulgaricus, lactobacillus paracasei, lactobacillus fermentum, lactobacillus rhamnosus, bifidobacterium bifidum and bifidobacterium longum.
in the present embodiment, lactobacillus salivarius and lactobacillus plantarum are selected. The Lactobacillus salivarius can improve allergic constitution, prevent recurrent allergic attack probiotic strain, and regulate allergic constitution. The lactobacillus plantarum has a plurality of health-care effects, such as immunoregulation effect; pathogenic bacteria have inhibiting effect; reducing serum cholesterol levels and preventing cardiovascular disease; maintaining the flora balance in the intestinal tract; promoting the absorption of nutrient substances; relieving lactose intolerance; inhibiting the formation of tumor cells, etc. However, the use of these two probiotics in feminine hygiene products has not been described.
immunoglobulin E (IgE) is an antibody for mediating anaphylactic reaction, the content of IgE in serum of normal human is very little, and the IgE in serum of some people with allergic constitution is 1-10 times higher than that of normal people. We refer to the population with excessive "total IGE" value as the "allergic constitution" population. Research shows that the antiallergic lactobacillus salivarius and the lactobacillus plantarum can relieve and even treat a plurality of allergic diseases by reducing serum IgE.
the serum of a patient suffering from exogenous asthma in a hospital is entrusted to perform IgE detection on various inactivated probiotics. The reduction of IgE by the lactobacillus salivarius and the lactobacillus plantarum is found to be more remarkable. The details are given in the following table.
For lactobacillus salivarius and lactobacillus plantarum, guinea pig is used for skin allergy experiment, lactobacillus salivarius and lactobacillus plantarum are contacted with skin mucosa of guinea pig for 2 times every week, each time is more than 4h, and the contact lasts for 5 weeks, and the skin is observed to have anaphylaxis such as erythema and edema. In the skin allergy experiment of guinea pig, skin allergic reactions such as obvious erythema, edema and the like and other systemic allergic reactions do not occur. The specific test conditions are listed in the table below.
a plurality of samples of the sanitary towel in the invention and the prior art are respectively selected and detected according to two main indexes of national standards, and are specifically listed in the following table:
from the above table, it can be seen that the inactivated probiotics of the present invention are more practical than the probiotics used in the prior patents.
In addition, the control requirement of the production link is lower than that of the live probiotics by using the inactivated probiotics, so that the production management is easier, the production cost is reduced, and the benefit is increased for enterprises. From the safety, because the species of the probiotics adapted by everyone are different, live bacteria are directly introduced, if the species is not the species required by the organism, the effect is not achieved, and even the condition of hurting the body is caused, however, the effective components in the live bacteria or the metabolites of the dead bacteria can promote the growth of most probiotics, and the construction of the self probiotic flora can be facilitated. Meanwhile, the method can easily meet the requirements of national standards on the detection of microorganisms of the products.
example 2: the tampon using probiotics is prepared from the tampon using probiotics, wherein the probiotics are added on a cotton belt in the production process of the tampon, and then the tampon is synthesized by pressing, and other processing technologies are the same as the example 1.
Example 3: a sanitary napkin using probiotics is prepared from the sanitary napkin using the probiotics, and the preparation process comprises the following steps:
s1: selecting any one of lactobacillus acidophilus, lactobacillus salivarius and lactobacillus plantarum, inactivating by irradiation, and drying to prepare probiotic powder;
S2: adding dipotassium glycyrrhizinate into probiotic powder, and adding water to prepare an aqueous solution for later use, wherein the probiotic powder accounts for 0.5 percent and the dipotassium glycyrrhizinate accounts for 1 percent by weight;
S3: preparing a sanitary cotton towel;
s4: compounding a degradable polylactic acid fiber hot-rolled non-woven fabric layer PLA on the surface layer of the sanitary napkin;
And S5, rolling and coating the probiotic water solution obtained in the step S2 on non-woven fabric, wherein the liquid applying amount is 10-30gsm, and quickly drying, packaging and warehousing.
Example 4: the sanitary napkin using the probiotics is characterized in that the probiotics are added on a cotton belt in the production process of the sanitary napkin substrate and then are pressed into the sanitary napkin, and other processing steps are the same as those in the embodiment 3.

Claims (5)

1. The sanitary cotton product using probiotics is characterized in that inactivated probiotics liquid or metabolite thereof is coated on the sanitary cotton product; the probiotic liquid is prepared by adding inactivated probiotic powder or metabolite into dipotassium glycyrrhizinate, and adding water to prepare aqueous solution, wherein the probiotic powder accounts for 0.5% and the dipotassium glycyrrhizinate accounts for 1% by weight; wherein the inactivated probiotics is one or a combination of lactobacillus salivarius and lactobacillus plantarum, and is obtained after inactivation, and the coating weight of the inactivated probiotics is 10-30 gsm.
2. The sanitary napkin using probiotics according to claim 1, wherein said sanitary napkin is a sanitary napkin or a tampon.
3. the sanitary napkin using probiotics as claimed in claim 1, wherein said sanitary napkin is a nonwoven fabric covering the core substrate.
4. The sanitary napkin using probiotics as claimed in claim 3, wherein said nonwoven fabric is made of degradable polylactic acid fiber PLA material.
5. The preparation method of the sanitary cotton product applying the probiotics is characterized by comprising the following preparation processes:
s1: selecting any one of lactobacillus salivarius and lactobacillus plantarum, inactivating by irradiation, and drying to prepare probiotic powder;
S2: adding dipotassium glycyrrhizinate into probiotic powder, and adding water to prepare an aqueous solution for later use, wherein the probiotic powder accounts for 0.5 percent and the dipotassium glycyrrhizinate accounts for 1 percent by weight;
S3: preparing a tampon or sanitary towel;
S4: coating a degradable polylactic acid fiber hot-rolled non-woven fabric layer PLA outside a tampon or a sanitary towel;
and S5, rolling and coating the probiotic water solution obtained in the step S2 on non-woven fabric, wherein the liquid applying amount is 10gsm, and quickly drying, packaging and warehousing.
CN201910809151.4A 2019-08-29 2019-08-29 sanitary cotton product using probiotics and preparation method thereof Pending CN110547915A (en)

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN112175867A (en) * 2020-09-30 2021-01-05 山东环亿生物科技有限公司 Functional non-woven fabric based on inactivated lactic acid bacteria

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Application publication date: 20191210