CN110537940A - Tumor cell sampling device - Google Patents
Tumor cell sampling device Download PDFInfo
- Publication number
- CN110537940A CN110537940A CN201910846154.5A CN201910846154A CN110537940A CN 110537940 A CN110537940 A CN 110537940A CN 201910846154 A CN201910846154 A CN 201910846154A CN 110537940 A CN110537940 A CN 110537940A
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- China
- Prior art keywords
- plate
- tumor cell
- guide
- hole
- sampling device
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
Abstract
The invention relates to the technical field of machinery, in particular to a tumor cell sampling device which comprises a lower holding plate, wherein a lower fixing plate is arranged on the lower holding plate, an arc-shaped rubber pad is arranged on the lower surface of the lower holding plate, an upper holding plate is arranged above the lower holding plate, an upper fixing plate is arranged on the upper holding plate, the lower fixing plate and the upper fixing plate are opposite to each other in position, a limiting plate is arranged above the upper fixing plate, fixing columns are arranged on the lower surface of the upper fixing plate, sampling needles are vertically distributed on the fixing columns, and a bottom plate is arranged below the lower fixing plate. The invention has simple operation, convenient use and high sampling efficiency, and relieves the pain of patients to a certain extent.
Description
Technical Field
The invention relates to the technical field of machinery, in particular to a tumor cell sampling device.
Background
Tumor refers to a new organism formed by local histiocyte hyperplasia under the action of various tumorigenic factors. When a patient suffering from tumor is treated, tumor cells need to be sampled firstly, and a tumor cell sampling device is needed when the tumor cells are sampled. In view of this, we propose a tumor cell sampling device.
Disclosure of Invention
The present invention is directed to a tumor cell sampling device, which solves the problems of inconvenient operation, time and labor consumption, and low working efficiency of the conventional tumor cell sampling device proposed in the background art.
In order to achieve the purpose, the invention provides the following technical scheme:
The utility model provides a tumour cell sampling device, includes the board of gripping down, be equipped with the bottom plate on gripping the board down, the lower surface that grips the board down is equipped with the arc rubber pad, the top of gripping the board down is equipped with grips the board, on grip and be equipped with the upper fixed plate on the board, the bottom plate with the position of upper fixed plate is just right each other, the top of upper fixed plate is equipped with the limiting plate, the lower surface of upper fixed plate is equipped with the fixed column, be equipped with the sample needle that is vertical form and distributes on the fixed column, the below of bottom plate still is equipped with the bottom plate.
Preferably, the lower fixing plate is internally provided with a first through hole communicated with the outside, the upper surface of the lower fixing plate is provided with four guide posts which are arranged in a matrix form and are vertically distributed, and the guide posts are surrounded by a return spring.
Preferably, the upper fixing plate is internally provided with a guide hole opposite to each guide post, the guide posts penetrate through the corresponding guide holes, the upper fixing plate is connected with the guide posts in a sliding manner, and the limiting plate is tightly adhered to the guide posts.
Preferably, one end of the return spring is closely adhered to the lower fixing plate, and the other end of the return spring is closely adhered to the upper fixing plate.
Preferably, the sampling needle is provided with a sampling hook.
preferably, the bottom plate is internally provided with a second through hole communicated with the outside, the fixing posts simultaneously penetrate through the first through hole and the second through hole, four support posts arranged in a matrix form are tightly bonded on the upper surface of the bottom plate, and the top ends of the support posts are tightly bonded on the lower fixing plate.
Preferably, a first threaded hole communicated with the outside is formed in the annular side face of the fixing column, a fastening bolt is arranged in the first threaded hole, the fastening bolt is in threaded connection with the first threaded hole, third through holes are vertically distributed in the fixing column, a guide groove is formed in the hole wall of each third through hole, a rectangular groove is further formed in the top wall of each third through hole, the first threaded hole and the rectangular groove are opposite in position, and the first threaded hole is communicated with the rectangular groove.
Preferably, the top end of the sampling needle is provided with a rectangular block, the rectangular block is located in the rectangular groove, a guide block is arranged on the sampling needle at a position opposite to the guide groove, and the guide block is located in the guide groove and is in sliding connection with the guide groove.
Preferably, the height of the rectangular block is equal to the depth of the rectangular groove.
Preferably, the top surface of the guide block and the top surface of the sampling needle are located on the same plane.
Compared with the prior art, the invention has the beneficial effects that:
1. According to the invention, through the arranged sampling needle and the sampling hook arranged on the sampling needle, when the upper holding plate is pressed, the upper holding plate moves downwards to drive the sampling needle to pierce the skin and pierce the tumor cells, and then when the upper holding plate is released, the upper holding plate is driven to automatically reset under the action of the elastic force of the reset spring, and at the moment, part of the tumor cells are left on the sampling hook, and then the tumor cells on the sampling hook are taken out for detection.
2. The invention is convenient to fix the sampling needle through the arranged fastening bolt, is also convenient to replace the sampling needle, realizes one needle injection by one person, avoids cross infection and solves the problem that the sampling needle on the common tumor cell sampling device is inconvenient to install and disassemble.
3. According to the invention, through the arrangement of the first screw and the sleeve, the depth of the tail end of the sampling needle penetrating into the skin can be conveniently adjusted, so that medical staff can adjust the sampling needle according to the thickness of the fat under the skin of a patient, a better sampling effect can be conveniently achieved, and the problems that the depth of the sampling needle penetrating into the skin on a common tumor cell sampling device is always consistent, and tumor cells cannot be taken out in time under certain conditions are solved.
Drawings
FIG. 1 is a schematic structural view of example 1 of the present invention;
FIG. 2 is an exploded view of example 1 of the present invention;
FIG. 3 is a schematic view of the structure of the sampling needle and the sampling hook of the present invention;
FIG. 4 is a schematic structural view of example 2 of the present invention;
FIG. 5 is an enlarged view taken at A of FIG. 4 in accordance with the present invention;
FIG. 6 is an enlarged view taken at B of FIG. 4 in accordance with the present invention;
FIG. 7 is a cross-sectional view of a stationary post according to the present invention;
FIG. 8 is a schematic structural view of example 3 of the present invention;
FIG. 9 is an enlarged view taken at C of FIG. 8 in accordance with the present invention;
FIG. 10 is a schematic view of a first screw of the present invention;
Fig. 11 is a schematic structural diagram of embodiment 4 of the present invention.
in the figure: 1. a lower grip plate; 10. a lower fixing plate; 101. a first through hole; 102. a guide post; 103. a return spring; 11. an arc-shaped rubber pad; 12. an upper grip plate; 13. an upper fixing plate; 131. a guide hole; 14. a limiting plate; 15. fixing a column; 16. a sampling needle; 161. a sampling hook; 17. a base plate; 171. a second through hole; 172. a support pillar; 2. a first threaded hole; 20. fastening a bolt; 21. a third through hole; 22. a guide groove; 23. a rectangular groove; 3. a rectangular block; 4. a guide block; 5. a first screw; 50. a second threaded hole; 6. a sleeve; 60. a third threaded hole; 61. a second screw; 7. a non-slip mat.
Detailed Description
the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second", "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first", "second", "third" may explicitly or implicitly include one or more of the features. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
Example 1
As a first embodiment of the present invention, a tumor cell sampling device, as shown in fig. 1 to 3, comprises a lower holding plate 1, a lower fixing plate 10 is disposed on the lower holding plate 1, a first through hole 101 communicating with the outside is disposed in the lower fixing plate 10, four guide posts 102 arranged in a matrix and vertically distributed are disposed on the upper surface of the lower fixing plate 10, a return spring 103 is wound on the guide posts 102, an arc-shaped rubber pad 11 is disposed on the lower surface of the lower holding plate 1, an upper holding plate 12 is disposed above the lower holding plate 1, an upper fixing plate 13 is disposed on the upper holding plate 12, one end of the return spring 103 is tightly adhered on the lower fixing plate 10, the other end of the return spring 103 is tightly adhered on the upper fixing plate 13, a guide hole 131 communicating with the outside is disposed in the upper fixing plate 13 at a position facing each guide post 102, the guide post 102 passes through the corresponding guide hole 131, the upper fixing plate 13 is connected with the guide post 102 in a sliding manner, and the lower fixing plate 10 and the upper fixing plate 13 are opposite to each other.
in this embodiment, the lower holding plate 1 and the lower fixing plate 10 are integrally formed, and the upper holding plate 12 and the upper fixing plate 13 are integrally formed, so as to ensure structural firmness and make them less prone to damage.
Specifically, the cross-section of arc rubber pad 11 is the arc, improves medical personnel's comfort of gripping arc rubber pad 11.
The top of upper fixed plate 13 is equipped with limiting plate 14, limiting plate 14 closely bonds on guide post 102, the lower surface of upper fixed plate 13 closely bonds and has fixed column 15, be equipped with the sampling needle 16 that is vertical form distribution on fixed column 15, be equipped with sample hook 161 on the sampling needle 16, the below of lower fixed plate 10 still is equipped with bottom plate 17, set up the second through-hole 171 that is linked together with the external world in the bottom plate 17, first through-hole 101 and second through-hole 171 are passed simultaneously to fixed column 15, the upper surface of bottom plate 17 closely bonds and has four support columns 172 that are the matrix and arrange, the top of support column 172 closely bonds on lower fixed plate 10.
Furthermore, the upper fixing plate 13 is limited by the limiting plate 14, so that the upper fixing plate 13 and the guide post 102 are prevented from being separated from each other.
In this embodiment, by arranging the sampling needle 16 and the sampling hook 161, the medical staff holds the lower holding plate 1, the bottom plate 17 is pressed against the position of the tumor cell on the skin of the patient, then presses the upper holding plate 12 downwards, the upper holding plate 12 moves downwards to drive the fixing column 15 to move downwards, the fixing column 15 moves downwards to drive the sampling needle 16 to pierce the skin of the patient, and simultaneously, the sampling needle 16 pierces the tumor, then the upper holding plate 12 is released, at this time, under the elastic force of the return spring 103, the upper holding plate 12 is ejected upwards, so that the sampling needle 16 is pulled out from the skin of the patient, the sampling hook 161 is just like a hook, part of the tumor cell is left at the sampling hook 161, and then the tumor cell at the sampling hook 161 is detected, the operation process is convenient and fast, and the inconvenience, time consumption and labor consumption of the general tumor cell sampling device are solved, and the working efficiency is low.
Example 2
As a second embodiment of the present invention, in order to facilitate the installation and the detachment of the sampling needle 16, and realize one needle for one person, and avoid bad infection, the present inventors improve the fixing post 15 and the sampling needle 16, as shown in fig. 4 to 7, as a preferred embodiment, a first threaded hole 2 communicated with the outside is opened on the annular side surface of the fixing post 15, a fastening bolt 20 is arranged in the first threaded hole 2, the fastening bolt 20 is in threaded connection with the first threaded hole 2, a third through hole 21 distributed in a vertical shape is opened in the fixing post 15, a guide groove 22 is opened on the hole wall of the third through hole 21, a rectangular groove 23 is further provided on the top wall of the third through hole 21, the positions of the first threaded hole 2 and the rectangular groove 23 are opposite to each other, the first threaded hole 2 is communicated with the rectangular groove 23, a rectangular block 3 is provided on the top end of the sampling needle 16, the rectangular block 3 is located in the rectangular, the sampling needle 16 is provided with a guide block 4 at a position opposite to the guide groove 22, and the guide block 4 is positioned in the guide groove 22 and is in sliding connection with the guide groove 22.
In this embodiment, the third through hole 21 is communicated with the outside, so that the sampling needle 16 can be inserted into the third through hole 21.
Specifically, the height of the rectangular block 3 is equal to the depth of the rectangular groove 23, so that the rectangular block 3 can be correctly installed in the rectangular groove 23.
furthermore, the top surface of the guide block 4 and the top surface of the sampling needle 16 are located on the same plane, so that when the guide block 4 moves to the end of the guide groove 22, the top surface of the rectangular block 3 just abuts against the groove wall of the rectangular groove 23, and whether the sampling needle 16 is installed in place or not is judged conveniently.
in addition, through the guide way 22 and the guide block 4 that set up, the staff of being convenient for is correct installs sampling needle 16 in third through-hole 21, avoids sampling needle 16's mounted position to make mistakes, causes fastening bolt 20 can't support on rectangular block 3, can not realize giving the compressing tightly rectangular block 3 promptly, finally causes sampling needle 16 to drop from third through-hole 21.
It should be noted that the width and length of the rectangular block 3 are smaller than the diameter of the cross-sectional circle of the sampling needle 16, so as to ensure that the rectangular block 3 can be inserted into the third through hole 21, and further ensure that the rectangular block 3 can be inserted into the rectangular groove 23.
In this embodiment, through the fastening bolt 20 that is provided, align the guide block 4 on the sampling needle 16 with the guide groove 22, and insert the sampling needle 16 into the third through-hole 21, when the rectangular block 3 supports on the cell wall of the rectangular groove 23, that is, when the sampling needle 16 has been inserted into the bottom end of the third through-hole 21, tighten the fastening bolt 20 again, the fastening bolt 20 will support the rectangular block 3 on the cell wall of the rectangular groove 23, thereby realize fixing the sampling needle 16, when dismantling, unscrew the fastening bolt 20, take out the sampling needle 16, the problem that the sampling needle on the general tumor cell sampling device is inconvenient to install and dismantle is solved.
Example 3
As a third embodiment of the present invention, in order to adjust the depth of the sampling needle 16 penetrating into the skin of the patient, the present inventors modified the fixing post 15 and the sampling needle 16, as a preferred embodiment, as shown in fig. 8 to 10, the lower surface of the upper fixing plate 13 is further tightly adhered with a first screw 5, a second threaded hole 50 communicating with the outside is formed in the first screw 5, a vertically distributed sleeve 6 is tightly adhered to the upper surface of the fixing post 15, a third threaded hole 60 communicating with the outside is formed in the sleeve 6, the third threaded hole 60 is in threaded connection with the first screw 5, a second screw 61 is tightly adhered to the wall of the third threaded hole 60, and the second screw 61 is in threaded connection with the second threaded hole 50.
In this embodiment, the screw thread on the first screw rod 5 is the same with the screw thread on the second screw rod 61 in the direction of rotation, and the screw thread in the second screw hole 50 is the same with the screw thread in the third screw hole 60 in the direction of rotation, and when guaranteeing the screw thread connection of the first screw rod 5 and the third screw hole 60, also screw thread connection between the second screw rod 61 and the second screw hole 50 to guarantee that it is difficult for taking place to break away from each other between the first screw rod 5 and the sleeve 6.
In this embodiment, through the first screw rod 5 that sets up, sleeve 6 and second screw rod 61, when rotating sleeve 6, because threaded connection between third screw hole 60 and the first screw rod 5, also threaded connection between second screw rod 61 and the second screw hole 50, so realize sleeve 6 in the pivoted, can reciprocate, thereby realize highly adjusting sampling needle 16, further realize adjusting the degree of depth that sampling needle 16 punctures in the patient skin, the degree of depth that the skin was impaled to the sampling needle on having solved general tumor cell sampling device remains unanimous all the time, under certain circumstances, the problem of tumor cell can't in time be taken out.
example 4
In order to prevent the bottom plate 17 from slipping when placed on the skin of a patient as a fourth embodiment of the present invention, the present inventor modified the bottom plate 17, and as a preferred embodiment, the bottom surface of the bottom plate 17 was further closely adhered with a non-slip mat 7 as shown in fig. 11.
In this embodiment, the non-slip mat 7 is made of a PVC material, and the PVC material has the characteristics of good mechanical properties, extremely strong acid and alkali resistance, low softening point, and stable chemical properties.
Specifically, a through hole communicated with the outside is also formed in the non-slip mat 7, and the position and the size of the through hole in the non-slip mat 7 are the same as those of the second through hole 171, so that the non-slip mat 7 is ensured not to influence the normal up-and-down movement of the fixing column 15.
in this embodiment, through the non-slip mat 7 that sets up, the frictional force between bottom plate 17 and the patient skin is increased, the phenomenon of skidding can not appear when making bottom plate 17 and patient skin contact.
Before the tumor cell sampling device is used, the guide block 4 on the sampling needle 16 is aligned to the guide groove 22, the sampling needle 16 is inserted into the third through hole 21, when the rectangular block 3 is abutted to the groove wall of the rectangular groove 23, namely the sampling needle 16 is inserted into the bottom end of the third through hole 21, the fastening bolt 20 is screwed, and the fastening bolt 20 abuts the rectangular block 3 on the groove wall of the rectangular groove 23, so that the sampling needle 16 is fixed;
When the medical needle is used, a medical worker rotates the sleeve 6 according to the thickness of subcutaneous fat of a patient to ensure that the sampling needle 16 can pierce the position of a tumor cell after the height of the sampling needle is adjusted, then the medical worker holds the lower holding plate 1 by a hand, supports the anti-skid pad 7 on the position of the tumor cell on the skin of the patient, then presses the upper holding plate 12 downwards, moves the upper holding plate 12 downwards to drive the fixing column 15 to move downwards, moves the fixing column 15 downwards to drive the sampling needle 16 to pierce the skin of the patient, simultaneously ensures that the sampling needle 16 pierces the tumor, then loosens the upper holding plate 12, and pushes the upper holding plate 12 upwards under the action of the elastic force of the reset spring 103, so that the sampling needle 16 is pulled out of the skin of the patient, the sampling hook 161 is just like a hook, and part of the tumor cell is left at the sampling hook 161;
After the use, unscrew fastening bolt 20, take out sampling needle 16, again to sample the tumor cell of hook 161 department detect can, it is inconvenient to have solved its operation of general tumor cell sampling device, consuming time power, and the problem that work efficiency is low.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. a tumor cell sampling device comprising a lower holding plate (1), characterized in that: be equipped with bottom plate (10) down on gripping board (1), the lower surface of gripping board (1) down is equipped with arc rubber pad (11), the top of gripping board (1) down is equipped with grips board (12), on grip and be equipped with upper fixed plate (13) on board (12), bottom plate (10) with the position of upper fixed plate (13) is just right each other, the top of upper fixed plate (13) is equipped with limiting plate (14), the lower surface of upper fixed plate (13) is equipped with fixed column (15), be equipped with on fixed column (15) and be vertical form distribution's sample needle (16), the below of bottom plate (10) still is equipped with bottom plate (17).
2. The tumor cell sampling device of claim 1, wherein: set up first through-hole (101) that are linked together with the external world in lower fixed plate (10), the upper surface of lower fixed plate (10) is equipped with four and is the matrix and arranges and be guide post (102) that vertical form distributes, it has reset spring (103) to surround on guide post (102).
3. The tumor cell sampling device of claim 2, wherein: the guide holes (131) communicated with the outside are formed in the positions, opposite to the guide columns (102), in the upper fixing plate (13), the guide columns (102) penetrate through the corresponding guide holes (131), the upper fixing plate (13) is in sliding connection with the guide columns (102), and the limiting plates (14) are tightly bonded on the guide columns (102).
4. the tumor cell sampling device of claim 3, wherein: one end of the return spring (103) is tightly adhered to the lower fixing plate (10), and the other end of the return spring (103) is tightly adhered to the upper fixing plate (13).
5. The tumor cell sampling device of claim 1, wherein: the sampling needle (16) is provided with a sampling hook (161).
6. The tumor cell sampling device of claim 2, wherein: set up second through-hole (171) that are linked together with the external world in bottom plate (17), fixed column (15) pass simultaneously first through-hole (101) and second through-hole (171), the upper surface of bottom plate (17) closely bonds has four support columns (172) that are the matrix and arrange, the top of support column (172) closely bonds on lower fixed plate (10).
7. The tumor cell sampling device of claim 1, wherein: the fixing column is characterized in that a first threaded hole (2) communicated with the outside is formed in the annular side face of the fixing column (15), a fastening bolt (20) is arranged in the first threaded hole (2), the fastening bolt (20) is in threaded connection with the first threaded hole (2), third through holes (21) distributed in a vertical shape are formed in the fixing column (15), a guide groove (22) is formed in the hole wall of each third through hole (21), a rectangular groove (23) is further formed in the top wall of each third through hole (21), the positions of the first threaded hole (2) and the rectangular groove (23) are opposite to each other, and the first threaded hole (2) is communicated with the rectangular groove (23).
8. The tumor cell sampling device of claim 7, wherein: the top of sample needle (16) is equipped with rectangular block (3), rectangular block (3) are located in rectangular channel (23), it is just right on sample needle (16) the position of guide way (22) is equipped with guide block (4), guide block (4) are located in guide way (22) and with guide way (22) sliding connection.
9. The tumor cell sampling device of claim 8, wherein: the height of the rectangular block (3) is equal to the depth of the rectangular groove (23).
10. The tumor cell sampling device of claim 8, wherein: the top surface of the guide block (4) and the top surface of the sampling needle (16) are positioned on the same plane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910846154.5A CN110537940A (en) | 2019-09-09 | 2019-09-09 | Tumor cell sampling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910846154.5A CN110537940A (en) | 2019-09-09 | 2019-09-09 | Tumor cell sampling device |
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| Publication Number | Publication Date |
|---|---|
| CN110537940A true CN110537940A (en) | 2019-12-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910846154.5A Pending CN110537940A (en) | 2019-09-09 | 2019-09-09 | Tumor cell sampling device |
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| CN (1) | CN110537940A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110974342A (en) * | 2019-12-09 | 2020-04-10 | 李联辉 | Hand-operated bone drill with anesthesia function |
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Application publication date: 20191206 |