CN110521881A - A kind of yellow eel disease resistance nutritional agents and preparation method thereof - Google Patents

A kind of yellow eel disease resistance nutritional agents and preparation method thereof Download PDF

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Publication number
CN110521881A
CN110521881A CN201910859629.4A CN201910859629A CN110521881A CN 110521881 A CN110521881 A CN 110521881A CN 201910859629 A CN201910859629 A CN 201910859629A CN 110521881 A CN110521881 A CN 110521881A
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China
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yellow eel
disease resistance
nutritional agents
parts
film
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CN201910859629.4A
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Chinese (zh)
Inventor
冯碧凤
安远峰
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Tongren Wanshan Aquaculture Station
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Tongren Wanshan Aquaculture Station
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Priority to CN201910859629.4A priority Critical patent/CN110521881A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Abstract

The invention belongs to technical field of aquaculture, especially a kind of yellow eel disease resistance nutritional agents and preparation method thereof;The yellow eel disease resistance nutritional agents is prepared from the following raw materials by weight: 4-5 parts of Chinese medical extracts, 8-10 parts of pharmaceutical carriers, film, 2-3 especially film in 0.5-1 parts.Preparation method are as follows: Chinese medical extract and pharmaceutical carrier are first mixed and made into little particle medicament;Then using lotion made of interior film to little particle medicament, just coated granule is obtained;Coating is carried out to get yellow eel disease resistance nutritional agents to first coated granule using slurries made of outer film again.Yellow eel disease resistance nutritional agents provided by the invention, stability is good, had good sustained release effect kills effect with stronger to bacteriums such as Aerononas punctata, white Pi Jimao bacillus, Pseudomonas fluorescens, can effectively prevent the generation of the diseases such as yellow eel putrid skin disease, tail, white skin disease.

Description

A kind of yellow eel disease resistance nutritional agents and preparation method thereof
Technical field
The invention belongs to technical field of aquaculture, especially a kind of yellow eel disease resistance nutritional agents and preparation method thereof.
Background technique
Yellow eel (Monopterus albus) also known as swamp eel, snake fish etc. close gill Gyrinocheilidae swamp eel category animal, are distributed in Asia The southeast, China, western North Korea, South Japan, Philippine, Java and Burma.For yellow eel at two kinds of distribution in China, a kind of is normal The swamp eel seen is mountain swamp eel there are also one kind, is all distributed on river, cloud, expensive, Chongqing, Hunan, Hubei Province, Anhui, Henan and Guangdong and Guangxi Provinces and other places.Chang Sheng It lives in the Muddy Bottoms bottom such as rice field, He Xi, pond, lake layer.
Ricefield eel meat nature and flavor are sweet, warm, there is the effect of bowl spares benefit blood, governance wasting, civil to be used as medicine, can treat cough due to consumptive disease, The diseases such as damp and hot body itches, hemorrhoid complicated by anal fistula, intestines wind anal fistula, deafness.Swamp eel head cineration, empty stomach heat wine take, and can control the hard pain of women's cream core.Its bone It is used as medicine, simultaneous to control ulcer on the shank, curative effect is quite significant.During its drop of blood is pleasant, otitis media purulenta chronica can be controlled;Nosebleed epistaxis can be controlled by instilling in nose (nosebleed);The especially outer used time can control facial paralysis, facial palsy.With the raising of modern life level, Ren Menyue More focus on the health value of fish food, the market demand of yellow eel is increasing, and the potentiality of eel cultivation development are very big.
Yellow eel is saprophagous animal, disease is easily generated in breeding process, and its disease usually easily infects, causes yellow eel big Area is dead, causes economic loss.Also there are a small number of study on prevention about yellow eel disease at present.Application No. is CN 201711250120.7 patent discloses a kind of yellow eel disease resistance feed, the raw material including following parts by weight: fly-maggot protein 10 ~12 parts, it is 13~15 parts of fish meal, 0.8~1.2 part of choline chloride, 1~2 part of inorganic salt mixt, 0.5~0.8 part of vitamin, big 3~5 parts of garlic, 20~30 parts of tankage, 20~30 parts of coarse food grain muffin, 2~4 parts of yeast powder, 5~10 parts of vinasse, tapioca starch 10~15 parts, 0.5~1 part of additive.Although the feed that the patent provides has certain control efficiency to yellow eel disease, Prevention and treatment dynamics is weaker.
Summary of the invention
In order to solve the above technical problems existing in the prior art, the present invention provides a kind of anti-yellow eel disease resistance nutrition Agent and preparation method thereof is realized particular by following technical scheme:
A kind of yellow eel disease resistance nutritional agents, is prepared from the following raw materials by weight: 4-5 parts of Chinese medical extracts, 8-10 parts Film, 2-3 especially film in pharmaceutical carrier, 0.5-1 parts.
Preferably, the Chinese medical extract is prepared from the following raw materials 6-10 parts of Chinese tallowtree leafs, 1-2 portions of arbor-vitaes by weight Leaf, 6-10 portions of turmerics, the 1-2 parts of tubers of stemona, 1-2 portions of folium isatidis, 3-4 parts of mulberry leaf, 3-6 parts of granatums, 1-2 portions of Verbena officinalis, 3-6 parts it is white The root of Dahurian angelica, 3-4 part rhizoma anemarrhenae, 2-3 portions of Schisandra chinensis.
Preferably, the Chinese medical extract the preparation method comprises the following steps: each Chinese medicine is pulverized and mixed, 8-10 times of water is added and decocts 3- 4h, it is cooling as room temperature, obtain decocting for Chinese herbal medicine object;The halimasch that its quality 0.03-0.04% is added into decocting for Chinese herbal medicine object exists 2-3d is handled at 25-30 DEG C, the lactic acid bacteria for adding 0.01-0.02% handles 1-2d at 25-30 DEG C, is homogenized, sterilizing;Again will Gained slurries are condensed into paste at 50-60 DEG C to get Chinese medical extract.
Preferably, the pharmaceutical carrier is made of chitosan, alginic acid by the mass ratio mixing of 1:2-3.
Preferably, the interior film is made of Chinese medical extract, animal collagen by the mass ratio of 1:1-2.
Preferably, the outer film is made of fish meal, red worm powder, glycine betaine, alginic acid by the mass ratio of 3-4:1-2:1:1
Preferably, the yellow eel disease resistance nutritional agents the preparation method comprises the following steps:
(1) it takes Chinese medical extract to mix with pharmaceutical carrier, 6-8 times of water of its quality is added after mixing evenly, be sent to high speed and cut It cuts in machine and 10min is emulsified with the rate of 15000r/min, obtain mixed emulsion;
(2) it after mixed emulsion being freeze-dried into powder, is sent into pelletizer and is prepared into the little particle medicine of 0.5-0.6mm Agent;
(3) it takes interior film and 4-5 times of water of its quality to be sent in high-speed shearing machine and 4min is emulsified with the rate of 15000r/min, Obtain emulsion;Then little particle medicament is added in coating machine, using emulsion to its coating, is dried, obtain just coating Grain;
(4) outer film is taken to add 4-5 times of water stirring that slurries are made;Then first coated granule is added in coating machine, using slurry Liquid dries to get yellow eel disease resistance nutritional agents its coating.
Preferably, the application method of the yellow eel disease resistance nutritional agents are as follows: in the preceding 1.5-2h of each feeding yellow eel feed Yellow eel disease resistance nutritional agents is fed, was fed every 4-5 days once, feeding volume is the 1-1.5% of yellow eel feed.
The beneficial effects of the present invention are:
The Chinese medicines such as Chinese tallowtree leaf, cacumen biotae, turmeric, the tuber of stemona are used in combination false to Aerononas punctata, white Pi Jimao bacillus, fluorescence The bacteriums such as monad kill effect with stronger, can effectively prevent the hair of the diseases such as yellow eel putrid skin disease, tail, white skin disease It is raw.Chinese medicine is handled using lactic acid bacteria, halimasch, the bioactivity of effective component of chinese medicine can be improved, reduces the thorn of Chinese medicine Swash property, promotes absorption of the yellow eel to effective component of chinese medicine.Chinese medical extract is handled using pharmaceutical carrier, Chinese medicine can be enhanced The stability of effective component in extract, can in yellow eel body slow release, avoid effective component of chinese medicine concentrate release and Stimulation is generated to yellow eel.Coating is carried out to little particle medicament using interior film, outer film, interior film is relative to little particle medicine Agent effective component of chinese medicine therein is few, and sustained release is very fast, can quickly generate prevention and treatment after the dispensing of yellow eel disease resistance nutritional agents and make With;Outer film is yellow eel preference substance, yellow eel can be attracted to ingest.
Yellow eel disease resistance nutritional agents provided by the invention, stability is good, had good sustained release effect, to Aerononas punctata, white skin pole The bacteriums such as hair bacillus, Pseudomonas fluorescens kill effect with stronger, can effectively prevent yellow eel putrid skin disease, tail, white skin The generation of the diseases such as disease.
Specific embodiment
It is limited below with reference to specific embodiment technical solution of the present invention is further, but claimed Range is not only limited to made description.
Embodiment 1
A kind of yellow eel disease resistance nutritional agents, is prepared from the following raw materials by weight: 4kg Chinese medical extract, 8kg drug carry The outer film of film, 2kg in body, 0.5kg.
The Chinese medical extract is prepared from the following raw materials 6kg Chinese tallowtree leaf, 1kg cacumen biotae, 6kg turmeric, 1kg by weight The tuber of stemona, 1kg folium isatidis, 3kg mulberry leaf, 3kg granatum, 1kg Verbena officinalis, the 3kg root of Dahurain angelica, 3kg rhizoma anemarrhenae, 2kg Schisandra chinensis.
The Chinese medical extract the preparation method comprises the following steps: each Chinese medicine is pulverized and mixed, 8 times of water are added and decoct 3h, it is cooling as Room temperature obtains decocting for Chinese herbal medicine object;The halimasch that its quality 0.03% is added into decocting for Chinese herbal medicine object handles 2d at 25-30 DEG C, The lactic acid bacteria for adding 0.01% handles 1d at 25-30 DEG C, is homogenized, sterilizing;Gained slurries are condensed at 50-60 DEG C again Paste is to get Chinese medical extract.
The pharmaceutical carrier is made of chitosan, alginic acid by the mass ratio mixing of 1:2.
The interior film is made of Chinese medical extract, animal collagen by the mass ratio of 1:1.
The outer film is made of fish meal, red worm powder, glycine betaine, alginic acid by the mass ratio of 3:1:1:1
The yellow eel disease resistance nutritional agents the preparation method comprises the following steps:
(1) it takes Chinese medical extract to mix with pharmaceutical carrier, 6 times of water of its quality is added after mixing evenly, are sent to high speed shear 10min is emulsified with the rate of 15000r/min in machine, obtains mixed emulsion;
(2) it after mixed emulsion being freeze-dried into powder, is sent into pelletizer and is prepared into the little particle medicine of 0.5-0.6mm Agent;
(3) it takes interior film and 4 times of water of its quality to be sent in high-speed shearing machine and 4min is emulsified with the rate of 15000r/min, obtain To emulsion;Then little particle medicament is added in coating machine, using emulsion to its coating, is dried, obtain just coated granule;
(4) outer film is taken to add 4 times of water stirrings that slurries are made;Then first coated granule is added in coating machine, using slurries To its coating, dry to get yellow eel disease resistance nutritional agents.
The application method of above-mentioned yellow eel disease resistance nutritional agents are as follows: it is anti-to feed yellow eel in the preceding 1.5h of each feeding yellow eel feed Disease nutritional agents was fed once every 4 days, and feeding volume is the 1.5% of yellow eel feed.
Embodiment 2
A kind of yellow eel disease resistance nutritional agents, is prepared from the following raw materials by weight: 4.5kg Chinese medical extract, 8.2kg medicine The outer film of film, 2.5kg in object carrier, 0.6kg.
The Chinese medical extract be prepared from the following raw materials by weight 8kg Chinese tallowtree leaf, 1.2kg cacumen biotae, 8kg turmeric, The 1.2kg tuber of stemona, 2kg folium isatidis, 3.5kg mulberry leaf, 5kg granatum, 1.2kg Verbena officinalis, the 5kg root of Dahurain angelica, 4kg rhizoma anemarrhenae, the 3kg five tastes Son.
The Chinese medical extract the preparation method comprises the following steps: each Chinese medicine is pulverized and mixed, 10 times of water are added and decoct 3h, it is cooling as Room temperature obtains decocting for Chinese herbal medicine object;The halimasch that its quality 0.035% is added into decocting for Chinese herbal medicine object handles 3d at 25-30 DEG C, The lactic acid bacteria for adding 0.015% handles 1d at 25-30 DEG C, is homogenized, sterilizing;Gained slurries are concentrated at 50-60 DEG C again At paste to get Chinese medical extract.
The pharmaceutical carrier is made of chitosan, alginic acid by the mass ratio mixing of 1:2.
The interior film is made of Chinese medical extract, animal collagen by the mass ratio of 1:2.
The outer film is made of fish meal, red worm powder, glycine betaine, alginic acid by the mass ratio of 3:2:1:1
The yellow eel disease resistance nutritional agents the preparation method comprises the following steps:
(1) it takes Chinese medical extract to mix with pharmaceutical carrier, 7 times of water of its quality is added after mixing evenly, are sent to high speed shear 10min is emulsified with the rate of 15000r/min in machine, obtains mixed emulsion;
(2) it after mixed emulsion being freeze-dried into powder, is sent into pelletizer and is prepared into the little particle medicine of 0.5-0.6mm Agent;
(3) it takes interior film and 4 times of water of its quality to be sent in high-speed shearing machine and 4min is emulsified with the rate of 15000r/min, obtain To emulsion;Then little particle medicament is added in coating machine, using emulsion to its coating, is dried, obtain just coated granule;
(4) outer film is taken to add 5 times of water stirrings that slurries are made;Then first coated granule is added in coating machine, using slurries To its coating, dry to get yellow eel disease resistance nutritional agents.
The application method of above-mentioned yellow eel disease resistance nutritional agents are as follows: it is anti-to feed yellow eel in the preceding 1.6h of each feeding yellow eel feed Disease nutritional agents was fed once every 4 days, and feeding volume is the 1% of yellow eel feed.
Embodiment 3
A kind of yellow eel disease resistance nutritional agents, is prepared from the following raw materials by weight: 5kg Chinese medical extract, 10kg drug The outer film of film, 3kg in carrier, 1kg.
The Chinese medical extract be prepared from the following raw materials by weight 10kg Chinese tallowtree leaf, 2kg cacumen biotae, 10kg turmeric, The 2kg tuber of stemona, 2kg folium isatidis, 4kg mulberry leaf, 6kg granatum, 2kg Verbena officinalis, the 6kg root of Dahurain angelica, 4kg rhizoma anemarrhenae, 3kg Schisandra chinensis.
The Chinese medical extract the preparation method comprises the following steps: each Chinese medicine is pulverized and mixed, 10 times of water are added and decoct 4h, it is cooling as Room temperature obtains decocting for Chinese herbal medicine object;The halimasch that its quality 0.04% is added into decocting for Chinese herbal medicine object handles 3d at 25-30 DEG C, The lactic acid bacteria for adding 0.02% handles 2d at 25-30 DEG C, is homogenized, sterilizing;Gained slurries are condensed at 50-60 DEG C again Paste is to get Chinese medical extract.
The pharmaceutical carrier is made of chitosan, alginic acid by the mass ratio mixing of 1:3.
The interior film is made of Chinese medical extract, animal collagen by the mass ratio of 1:2.
The outer film is made of fish meal, red worm powder, glycine betaine, alginic acid by the mass ratio of 4:2:1:1
The yellow eel disease resistance nutritional agents the preparation method comprises the following steps:
(1) it takes Chinese medical extract to mix with pharmaceutical carrier, 8 times of water of its quality is added after mixing evenly, are sent to high speed shear 10min is emulsified with the rate of 15000r/min in machine, obtains mixed emulsion;
(2) it after mixed emulsion being freeze-dried into powder, is sent into pelletizer and is prepared into the little particle medicine of 0.5-0.6mm Agent;
(3) it takes interior film and 5 times of water of its quality to be sent in high-speed shearing machine and 4min is emulsified with the rate of 15000r/min, obtain To emulsion;Then little particle medicament is added in coating machine, using emulsion to its coating, is dried, obtain just coated granule;
(4) outer film is taken to add 5 times of water stirrings that slurries are made;Then first coated granule is added in coating machine, using slurries To its coating, dry to get yellow eel disease resistance nutritional agents.
The application method of above-mentioned yellow eel disease resistance nutritional agents are as follows: it is disease-resistant to feed yellow eel in the preceding 2h of each feeding yellow eel feed Evil nutritional agents was fed once every 5 days, and feeding volume is the 1.5% of yellow eel feed.
Comparative example 1
Comparative example 1 is not the difference from embodiment 1 is that handle little particle using interior film;Remaining same embodiment 1。
Comparative example 2
Comparative example 2 is not the difference from embodiment 1 is that handle first coated granule using outer film;Remaining is the same as real Apply example 1.
Comparative example 3
Comparative example 3 is the difference from embodiment 1 is that handle Chinese medical extract without carrier medicament;Remaining is the same as implementation Example 1.
Test example 1
455 tail of yellow eel with a batch, unified 10 monthly age of raising volume is taken, is randomly divided into 7 groups, every group of 65 tails;1-6 group is adopted respectively The yellow eel disease resistance nutritional agents made by embodiment 1-3 and comparative example 1-3 is fed;7 groups are control group, only feed yellow eel feeding Material does not feed yellow eel disease resistance nutritional agents;After continuously feeding 4 months, the yellow eels such as every group of yellow eel putrid skin disease, tail, white is counted The incidence and its death rate of the diseases such as skin disease;The results are shown in Table 1:
A situation arises for 1 yellow eel disease of table
Group Putrid skin disease incidence/% Tail incidence/% White skin disease incidence/% The death rate/%
Embodiment 1 4.62 3.07 10.78 0
Embodiment 2 3.07 6.15 9.23 0
Embodiment 3 4.62 7.69 9.23 0
Comparative example 1 3.07 13.85 10.78 0
Comparative example 2 13.84 16.92 24.61 6.15
Comparative example 3 10.76 13.85 16.92 3.07
Control group 24.62 18.46 32.30 10.78
It is important to point out that, above embodiments and test example are only limitted to do further technical solution of the present invention herein Elaboration and understanding, should not be understood as it is further to technical solution of the present invention limited, what those skilled in the art made The innovation and creation of non-protruding essential characteristics and marked improvement still fall within protection category of the invention.

Claims (8)

1. a kind of yellow eel disease resistance nutritional agents, which is characterized in that be prepared from the following raw materials by weight: 4-5 parts of traditional Chinese medicine extractions Object, 8-10 part pharmaceutical carrier, film, 2-3 especially film in 0.5-1 parts.
2. yellow eel disease resistance nutritional agents as described in claim 1, which is characterized in that the Chinese medical extract by weight by 6-10 parts of Chinese tallowtree leafs, 1-2 portions of cacumen biotaes, 6-10 portions of turmerics, the 1-2 parts of tubers of stemona, 1-2 portions of folium isatidis, 3-4 portions of mulberries are made in following raw material Leaf, 3-6 part granatum, 1-2 portions of Verbena officinalis, the 3-6 parts of roots of Dahurain angelica, 3-4 parts of rhizoma anemarrhenaes, 2-3 portions of Schisandra chinensis.
3. yellow eel disease resistance nutritional agents as claimed in claim 2, which is characterized in that the preparation method of the Chinese medical extract Are as follows: each Chinese medicine is pulverized and mixed, 8-10 times of water is added and decocts 3-4h, it is cooling as room temperature, obtain decocting for Chinese herbal medicine object;It is decocted to Chinese medicine The halimasch that its quality 0.03-0.04% is added in Stewed Dish handles 2-3d at 25-30 DEG C, adds the cream of 0.01-0.02% Sour bacterium handles 1-2d at 25-30 DEG C, is homogenized, sterilizing;Gained slurries are condensed into paste at 50-60 DEG C to get Chinese medicine again Extract.
4. yellow eel disease resistance nutritional agents as described in claim 1, which is characterized in that the pharmaceutical carrier is by chitosan, seaweed Acid mixes composition by the mass ratio of 1:2-3.
5. yellow eel disease resistance nutritional agents as described in claim 1, which is characterized in that the interior film is by Chinese medical extract, dynamic Object collagen is formed by the mass ratio of 1:1-2.
6. yellow eel disease resistance nutritional agents as described in claim 1, which is characterized in that the outer film is by fish meal, red worm powder, sweet tea Dish alkali, alginic acid are formed by the mass ratio of 3-4:1-2:1:1.
7. the preparation method of yellow eel disease resistance nutritional agents as described in claim 1, which comprises the following steps:
(1) it takes Chinese medical extract to mix with pharmaceutical carrier, 6-8 times of water of its quality is added after mixing evenly, is sent to high-speed shearing machine In 10min emulsified with the rate of 15000r/min, obtain mixed emulsion;
(2) it after mixed emulsion being freeze-dried into powder, is sent into pelletizer and is prepared into the little particle medicament of 0.5-0.6mm;
(3) it takes interior film and 4-5 times of water of its quality to be sent in high-speed shearing machine and 4min is emulsified with the rate of 15000r/min, obtain Emulsion;Then little particle medicament is added in coating machine, using emulsion to its coating, is dried, obtain just coated granule;
(4) outer film is taken to add 4-5 times of water stirring that slurries are made;Then first coated granule is added in coating machine, using slurries pair Its coating dries to get yellow eel disease resistance nutritional agents.
8. such as the application method of the described in any item yellow eel disease resistance nutritional agents of claim 1-7, which is characterized in that feeding every time The preceding 1.5-2h of food yellow eel feed feeds yellow eel disease resistance nutritional agents, feeds every 4-5 days once, and feeding volume is yellow eel feed 1-1.5%.
CN201910859629.4A 2019-09-11 2019-09-11 A kind of yellow eel disease resistance nutritional agents and preparation method thereof Pending CN110521881A (en)

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CN104273343A (en) * 2013-07-05 2015-01-14 青岛康地恩药业股份有限公司 Aquatic animal growth promoting traditional Chinese medicine compound preparation
CN103549219A (en) * 2013-11-19 2014-02-05 厦门星鲨动物保健品厂 Drug feed additive for promoting skin health of aquatic animals and preparation method thereof
CN105360713A (en) * 2015-11-04 2016-03-02 明光市永言水产(集团)有限公司 Growth-promoting monopterus albus feed and preparation method thereof
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