CN110507438A - A kind of tooth-implanting is taken root and preparation method thereof - Google Patents

A kind of tooth-implanting is taken root and preparation method thereof Download PDF

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Publication number
CN110507438A
CN110507438A CN201910808498.7A CN201910808498A CN110507438A CN 110507438 A CN110507438 A CN 110507438A CN 201910808498 A CN201910808498 A CN 201910808498A CN 110507438 A CN110507438 A CN 110507438A
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CN
China
Prior art keywords
tooth
implanting
screw thread
groove
diameter
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CN201910808498.7A
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Chinese (zh)
Inventor
姚向东
朱益明
姚超
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Nantong Hi Tech New Material Ltd By Share Ltd Today
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Nantong Hi Tech New Material Ltd By Share Ltd Today
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Priority to CN201910808498.7A priority Critical patent/CN110507438A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0016Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy polymeric material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0018Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/06Rod-shaped

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  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

The present invention discloses a kind of tooth-implanting and takes root and preparation method thereof, it is characterized by: it is 3500MW to 60 parts of 150000MW polylactic acid that the production method, which is selection weight average molecular weight, when being warmed to 60-95 DEG C makes polylactic acid in semifluid, 40 parts of nano-grade hydroxy apatite are added insensibly, it is rolled or is squeezed, the composite material is continued to heat when rolling or squeezing, keep the temperature at 70-90 DEG C, until two materials sufficiently merge crosslinking uniformly, then the PLA/HAP composite bar that diameter is 16mm to 98mm is squeezed out by extruder;Actual demand further according to tooth-implanting client processes taking root for tooth-implanting using material processing method is subtracted.The tooth-implanting, which is taken root, plants main body with screw type evagination including taper, it is equipped in main body and is installed and used for connection tooth-implanting stylobate screw, spiral groove (screw thread female groove) corresponding with evagination, the spiral groove (screw thread female groove) the effectively road groove number 4-12, the spiral-shafted implant wall thickness 1-2mm, planting body height 15-30mm, plantation outer diameter 1-15mm, interior diameter 1-11mm.

Description

A kind of tooth-implanting is taken root and preparation method thereof
Technical field
The present invention relates to Medical oral cavity repair materials, and in particular to take root to a kind of tooth-implanting and preparation method thereof.
Background technique
Tooth-implanting it is a kind of based on the substructure being implanted into bone tissue support, the agomphosis of maintenance top dental case Repair mode.It includes the support planting body (taking root) of lower part and dental case (corona) two parts on top.Implant is implanted into tooth Root of the tooth is served as in slot bone, increases artificial tooth stationarity, can preferably restore oral cavity chewing stress.It is using artificial material (such as gold Category, ceramics etc.) planting body is made, underwent operative method implanting tissue is interior and obtains the firm maintenance support of bone tissue, by special Device connected with mode support top dental case.It may when tooth-implanting will not be at table or speak as normal activity artificial tooth The danger for causing to block tracheae or esophagus is fallen off, there are also very long service life, aesthetic in appearance, just as natural teeth.
The implant (taking root) of existing tooth-implanting is most to use pure titanium metal, titanium alloy material, zirconia ceramics composite wood Material and coating material, high molecular material etc..Although metal and alloy material have good intensity and hardness, biological machine Tool adaptability and tissue, bone adaptability are not fine.Common high molecular material esters of acrylic acid, polytetrafluoroethyl-ne alkenes etc.. Although the chemical structure of high molecular material close to the natural polymer in organization of human body, is still easier by organism Degradation is to cause to stimulate.Have again because implant and corona majority are not that same producer is mating when the processing of these materials, or because of implant With stylobate, corona be not mating same producer or implant and stylobate is same producer but the reasons such as later period corona processing cause to pacify Cannot fit like a glove when dress with implant (taking root) causes root of the tooth (taking root) to loosen, and influences planting effect.
Human teeth usually contains organic matter and inorganic matter simultaneously, and ingredient is complex.Since homogenous material is by list The limitation of one structure generally can not meet the requirement of organism, therefore composite material is made extensively with the characteristics of its perfect performance With.Especially polylactic acid and hydroxyapatite synthetic composite material, polylactic acid (PLA) are a kind of biodegrade implantation material, tool There is good biocompatibility, hydroxyapatite (HA) is that a kind of biology with good biocompatibility and bone guided is living Property material, be the host inorganic composition of body bone tissue, can be used as a kind of bone inducible factor, new bone is guided to generate, realize material Material generates close synostosis with normal bone, and will not cause the adverse reactions such as rejection, inflammation, ponding, corrosion, with into The degradation of one step, is finally substituted by self bone tissue.
Summary of the invention
Present invention generally provides one kind to have compared with high-biocompatibility, and having can be with the plantation in conjunction with skeleton compactness Tooth is taken root and production method, final to realize that artificial tooth of repairing is similar to nature tooth.
To achieve the goals above, the present invention the following technical schemes are provided:
A kind of tooth-implanting is taken root and preparation method thereof, and it is 3500MW to 150000MW that the tooth-implanting, which takes root and selects weight average molecular weight, It 60 parts of polylactic acid, when being warmed to 60-95 DEG C makes polylactic acid in semifluid, is added uses the F127 to be for templated synthesis is mesoporous insensibly 20-50nm, length are 100 to 1000nm, and diameter is that 30-60nm is rodlike or 40 parts of flake nano grade hydroxyapatite, are ground Pressure squeezes, and continues to heat to the composite material when rolling or squeezing, keeps the temperature at 70-90 DEG C, until two materials fill Divide fusion crosslinking uniformly, then diameter is squeezed out as the PLA/HAP composite bar of 16mm to 98mm by extruder;Further according to tooth-implanting The actual demand of client processes taking root for tooth-implanting using material processing method is subtracted.
It is described subtract material method processing the following steps are included:
A, taking the PLA/HAP composite bar that diameter is 16mm to be divided into length is 15-30mm,
B, helical cavity (screw thread female groove) 2 is first processed by tapping machine or data control machining center, makes helical cavity (threaded female Slot) 2 effective 3 number of groove screw thread silk in the road 4-12;
C, after completing " b ", evagination silk 4 is carried out to screw type evagination plantation main body 1 using outer die head threading machine or numerical control machining center and is added Work, protrusion 4 part of silk is corresponding with the recessed silk 3 of spiral groove (screw thread female groove) 2 when the processing;
D, according to customer demand, when processing screw type evagination plantation main body 1, according to the diameter of spiral groove (screw thread female groove) 2 come It controls 5 thickness of wall and screw type evagination plants 1 overall diameter of main body.
E, taking diameter is the PLA/HAP composite bar of 98mm, is divided into the cake shape with a thickness of 15-30mm;
F, one-step shaping engraving tooth-implanting is carried out using digital-controlled carving machine to take root.
It is taken root by the above-mentioned tooth-implanting for subtracting the processing of material method, it is characterised in that: tooth-implanting is taken root conical banda as shown in Figure 1 There is the plantation main body 1 of the outer convex thread silk 6 of screw type, main body 1 is interior recessed equipped with spiral is installed and used for connection tooth-implanting stylobate screw Chamber (screw thread female groove) 2, the helical cavity (screw thread female groove) 2 is interior to be equipped with the road 4-12 groove screw thread silk 3, the spiral-shafted implant 1 2 further groove screw thread silk 3 of the corresponding helical cavity of outer convex thread silk 4 (screw thread female groove) between 5 thickness of wall be 1-2mm, described kind 1 height of implant is 15-30mm, overall diameter 1-15mm, and outer convex thread 4 can also design from brill and attack lines;Helical cavity (the spiral shell Line female groove) 2 interior diameter 1-11mm.
The present invention has following superiority compared with prior art:
It solves single high molecular material to be easy to be degraded to cause to stimulate by organism;
Solve the problems, such as that metallic composite bio-mechanical adaptability and tissue, bone adaptability is not strong;
It is not high to solve tooth-implanting stylobate and implant conjugation of (taking root), is easy loosening problem.
Detailed description of the invention
Fig. 1: tooth-implanting is taken root structure chart;
Fig. 2: production method route map.
Specific embodiment
The present invention is further illustrated with reference to the accompanying drawings and examples, embodiment the selection of material specification and method are not It is sole limitation, only does representative reference, it should be understood by those skilled in the art that: it can also be to recorded in following each embodiments Technical solution modify or some technical characteristics carried out the replacement of equivalent effect, and these modifications or substitutions, not The essence of corresponding technical solution is set to be detached from drip irrigation device of the embodiment of the present invention and range.
Case study on implementation 1: as shown in Fig. 2, a kind of tooth-implanting is taken root and preparation method thereof, preferable weight-average molecular weight is 3760 25 parts of polylactic acid powder, selecting weight average molecular weight is 15 parts of polylactic acid powder of 12750, and selecting weight average molecular weight is 123650 20 parts of polylactic acid powder.It is preferred that use F127 for templated synthesis it is mesoporous be 20-50nm, length is 100 to 1000nm, diameter is 30-60nm rod-like nano grade hydroxyapatite.First the polylactic acid powder of three kinds of molecular weight is placed on after mixing with heating In the roller of function, 80 degrees Celsius of thermostatic controls are adjusted the temperature to, and uninterruptedly rolled, is observing that polylactic acid heat melts When in semifluid shape, then 40 parts of nano-grade hydroxy apatite are added insensibly, are rolled, temperature control is kept when rolling At 80 DEG C, until two materials sufficiently merge crosslinking uniformly, then pour into double screw extruder for the material in roller, twin-screw is squeezed Machine cavity temperature and the control of discharge port mold temperature are 16mm round mouth mold with 20-50 meters per hour by diameter at 80 DEG C out Speed is squeezed out, and composite material goes out after mold through water cooling and air-cooled, keeps material indeformable, it is cooling after segmentation length be 50-100cm profile is spare.
A kind of tooth-implanting is taken root and preparation method thereof, it is described subtract the processing of material method the following steps are included:
A, taking diameter is 16mm, and it is 15mm that the PLA/HAP composite bar that length is 50cm, which is divided into length,
B, helical cavity (screw thread female groove) 2 is first processed by tapping machine or data control machining center, makes helical cavity (threaded female Slot) 2 effective 3 number of groove screw thread silk in the road 4-12;2 upper internal diameter of screw thread cavity is no more than 11mm, in cavity line bottom Diameter 1-3mm.
C, after completing " b ", evagination silk is carried out to screw type evagination plantation main body 1 using outer die head threading machine or numerical control machining center 4 processing, protrusion 4 part of silk is corresponding with the recessed silk 3 of helical cavity (screw thread female groove) 2 when the processing;
D, according to customer demand, when processing screw type evagination plantation main body 1, according to the diameter of helical cavity (screw thread female groove) 2 come 5 thickness of wall is controlled between 1-2mm, to guarantee the securement strength taken root, screw type evagination kind is guaranteed according to the requirement of design taper It plants the overall diameter suitable for reading of main body 1 and is not more than 15mm, conical lower portion is equal to or more than 1mm, and outer convex thread 4 can also design from brill and attack line Road.As shown in Figure 1.
Case study on implementation 2: as shown in Fig. 2, a kind of tooth-implanting is taken root and preparation method thereof, preferable weight-average molecular weight is 8532 25 parts of polylactic acid powder, selecting weight average molecular weight is 15 parts of polylactic acid powder of 25682, and selecting weight average molecular weight is 83560 20 parts of polylactic acid powder.It is preferred that use F127 for templated synthesis it is mesoporous be 36nm, width 100nm, diameter be 45nm sheet receive Meter level hydroxyapatite.The polylactic acid powder of three kinds of molecular weight is first placed on the roller with heating function after mixing In, 80 degrees Celsius of thermostatic controls are adjusted the temperature to, and uninterruptedly rolled, is observing that polylactic acid heat melts in semifluid shape When, then 40 parts of nano-grade hydroxy apatite are added insensibly, it is rolled, keeps temperature control at 80 DEG C when rolling, until Two materials sufficiently merge crosslinking uniformly, then the material in roller is poured into double screw extruder, double screw extruder cavity temperature Degree and the control of discharge port mold temperature are squeezed at 80 DEG C, by diameter for 98mm round mouth mold with 5-15 meters of speed per hour Out, composite material goes out after mold through water cooling and air-cooled, keeps material indeformable, it is cooling after segmentation length be 50-100cm profile It is spare.
It is described subtract material method processing the following steps are included:
A, taking diameter is the PLA/HAP composite bar of 98mm, is divided into the cake shape with a thickness of 15-30mm;
B, the cake shape PLA/HAP composite material of well cutting is placed in the fixture of digital-controlled carving machine, passes through numerical control device Design interface, the size data of the planting body carved as needed (taking root) requires and number using CAM carries out typesetting, a step Engraving is shaped to plantation main body 1 of the taper with the outer convex thread silk 4 of screw type, is equipped in main body 1 for connecting tooth-implanting stylobate spiral shell Silk installs and uses helical cavity (screw thread female groove) 2, is equipped with the road 4-12 groove screw thread silk 3 in the helical cavity (screw thread female groove) 2, Wall 5 between the 2 further groove screw thread silk 3 of the corresponding helical cavity of outer convex thread silk 4 (screw thread female groove) of the spiral-shafted implant 1 is thick For 1-2mm, 1 height of planting body is 15-30mm, overall diameter 1-15mm, and outer convex thread 4 can also design from brill and attack lines; The 2 interior diameter 1-11mm of helical cavity (screw thread female groove).As described in Figure 1, a kind of tooth-implanting of foregoing invention is taken root and its is made The case of method solves single high molecular material and is easy to be degraded to cause to stimulate by organism;Solves Metals composite Expect bio-mechanical adaptability and the not strong problem of tissue, bone adaptability;It solves tooth-implanting stylobate and implant (is taken root) conjugation It is not high, it is easy loosening problem, and production is simple, the time is short, precision is high, moderate, is suitble to promote the use of.

Claims (8)

1. a kind of tooth-implanting is taken root and preparation method thereof, it is characterised in that: the production method is to select the weight average molecular weight to be 3500MW to 60 parts of 150000MW polylactic acid, when being warmed to 60-95 DEG C makes polylactic acid in semifluid, nanoscale hydroxyl is added insensibly It 40 parts of base apatite, is rolled or is squeezed, the composite material is continued to heat when rolling or squeezing, is kept the temperature at 70-90 DEG C, until two materials sufficiently merge crosslinking uniformly, then the PLA/HAP that diameter is 16mm to 98mm is squeezed out by extruder Composite bar;Actual demand further according to tooth-implanting client processes taking root for tooth-implanting using material processing method is subtracted.
2. a kind of tooth-implanting is taken root and preparation method thereof according to claim 1, it is characterised in that: described to subtract the processing of material method The following steps are included:
A, taking the PLA/HAP composite bar that diameter is 16mm to be divided into length is 15-30mm,
B, spiral groove (screw thread female groove) 2 is first processed by tapping machine or data control machining center, makes spiral groove (threaded female Slot) 2 effective groove screw thread channel number in the road 4-12;
C, after completing " b ", evagination silk is carried out to screw type evagination plantation main body 1 using outer die head threading machine or numerical control machining center and is added Work, protrusion silk part is corresponding with the recessed silk of spiral groove (screw thread female groove) 2 when the processing;
D, according to customer demand, when processing screw type evagination plantation main body 1, according to the diameter of spiral groove (screw thread female groove) 2 come It controls wall thickness and screw type evagination plants 1 overall diameter of main body.
3. a kind of -2 tooth-implantings are taken root and preparation method thereof according to claim 1, it is characterised in that: the material method that subtracts adds Work the following steps are included:
A, taking diameter is the PLA/HAP composite bar of 98mm, is divided into the disk shape with a thickness of 15-30mm;
B, the cake shape PLA/HAP composite material of well cutting is placed in the fixture of digital-controlled carving machine, passes through numerical control device Design interface, the size data of the planting body carved as needed (taking root) requires and number using CAM carries out typesetting, a step Engraving molding.
4. a kind of tooth-implanting according to claim 2-3 is taken root and preparation method thereof, it is characterised in that: the tooth-implanting is taken root Include: plantation main body 1 of the taper with the outer convex thread silk 4 of screw type, is equipped in main body 1 for connection tooth-implanting stylobate screw installation Using helical cavity (screw thread female groove) 2, the road 4-12 groove screw thread silk 3, the spiral shell are equipped in the helical cavity (screw thread female groove) 2 Revolving 5 thickness of wall between the 2 further groove screw thread silk 3 of the corresponding helical cavity of outer convex thread silk 4 (screw thread female groove) of planting body 1 is 1- 2mm, 1 height of planting body are 15-30mm, overall diameter 1-15mm, and outer convex thread 4 can also design from brill and attack lines;It is described 2 interior diameter 1-11mm of helical cavity (screw thread female groove).
5. a kind of tooth-implanting is taken root and preparation method thereof according to claim 1, it is characterised in that: select the weight average molecular weight to be The polylactic acid 25 of 3500-8000 is divided, and selecting weight average molecular weight is 15 parts of polylactic acid of 8001-20000, and selection weight average molecular weight is 20 parts of the polylactic acid of 20001-150000.
6. a kind of tooth-implanting is taken root and preparation method thereof according to claim 1, it is characterised in that: nanometer hydroxyapatite choosing It is 100-1000nm with length, diameter is the mesoporous hydroxyapatite of stick sheet of 30-60nm.
7. a kind of tooth-implanting is taken root and preparation method thereof according to claim 6, it is characterised in that: nanometer hydroxyapatite is It is the mesoporous hydroxyapatite of templated synthesis using F127.
8. a kind of -4 tooth-implantings are taken root and preparation method thereof according to claim 1, it is characterised in that: evagination Design of Screw Thread has Lines is attacked from brill.
CN201910808498.7A 2019-08-29 2019-08-29 A kind of tooth-implanting is taken root and preparation method thereof Pending CN110507438A (en)

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