CN110506941A - A kind of pearl slurry and preparation method thereof containing Amino acid score powder - Google Patents
A kind of pearl slurry and preparation method thereof containing Amino acid score powder Download PDFInfo
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- CN110506941A CN110506941A CN201910612639.8A CN201910612639A CN110506941A CN 110506941 A CN110506941 A CN 110506941A CN 201910612639 A CN201910612639 A CN 201910612639A CN 110506941 A CN110506941 A CN 110506941A
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- pearl
- amino acid
- powder
- water
- preparation
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- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates to a kind of pearl slurry and preparation method thereof containing Amino acid score powder.The pearl slurry uses the raw material comprising pearl powder and water, is obtained by mixed grinding, further includes Amino acid score powder in the raw material.The present invention adds safe and reliable, especially edible dispersing agent in pearl slurry and improves its security performance while guaranteeing pearl slurry dispersion performance, can be applied to the fields such as food, drug, health care product.
Description
Technical field
The present invention relates to feedstock processing fields, and in particular to a kind of pearl slurry containing Amino acid score powder and its preparation
Method.
Background technique
Pearl mainly produces in pearl shellfish and pearl oyster shellfish mollusk body, and due to endocrine act on and generate contain
The mineral bead of calcium carbonate is as made of a large amount of small aragonite crystals set, and type is abundant, different, colorful.
The main component of pearl: calcium carbonate 91.72%, organic matter 5.94%, water 2.23%.In addition, also containing in pearl
A variety of inorganic microelements such as silver, lead, barium, lithium, aluminium, copper, iron, magnesium, manganese, sodium, zinc, silicon, titanium, strontium.
In addition to good aesthetic measure, pearl also has important health care and medical value.Pearl is medicinal in
State has more than 2000 years history." Haiyao Bencao, Oversea Materia Medica " of " book on Chinese herbal medicine is through collecting " of medical book " Mingyi Bielu ", beam generation when three states, the Tang Dynasty,
" Kaibao Bencao " of Song Dynasty, the Compendium of Material Medica of the Ming Dynasty, the Qing Dynasty 19 kinds of Leigon's Nature of Drugs in Songs etc. medical ancient books, all to pearl
Curative effect has specific record.
The Pharmacopoeia of the People's Republic of China and " dictionary of medicinal plant " indicate: pearl has calm the nerves arresting convulsion, shade removing, solution
Taking poison and growing muscle due and other effects, modern study also show pearl improve the immunity of the human body, delay senescence, freckle removing and whitening, supplement calcium etc.
Aspect all has unique effect.
It can be seen that pearl products suffer from huge application prospect in numerous areas such as food, drug, health care products.So
And pearl products are in the problem of application in above-mentioned field, pearl is as powdered inorganic material, dispersion performance
It is not ideal enough.Therefore, the dispersion performance that pearl how is improved using safety, especially edible dispersing agent, is promoted
It becomes those skilled in the art and endeavours the technical issues of solving jointly in the application in the fields such as food, drug, health care product.
Summary of the invention
To overcome defect and deficiency existing in the prior art, the invention discloses a kind of treasure containing Amino acid score powder
Pearl slurry.
The invention is realized by the following technical scheme:
A kind of preparation method of the pearl slurry containing Amino acid score powder, the pearl slurry, which uses, includes pearl powder
It with the raw material of water, is obtained by mixed grinding, further includes Amino acid score powder in the raw material.
Further, the additive amount of the Amino acid score powder is the 0.1%wt-2.0%wt of the pearl powder quality.
Further, the mass ratio of the pearl powder and water is pearl powder: water=(10-40): (60-90).
Further, the mass ratio of the pearl powder and water is pearl powder: water=(20-30): (70-80).
Further, the Amino acid score powder is compound, the polymer of amino acid or the salt of amino acid of amino acid
At least one of.
Further, the amino acid is aspartic acid, threonine, serine, glutamic acid, proline, glycine, the third ammonia
Acid, cystine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, lysine, histidine, arginine
One or more of.
Further, the Amino acid score powder is N- sodium lauroyl glutamate, N- cocounut oil acyl disodium glutamate, N- cocounut oil
Acyl sodium glutamate, N- sodium lauroyl sarcosine, N- myristoyl-N-methylaminoacetic acid sodium, N- Sodium Coco acylsarcosinate, N- oleoyl musculamine
Sour sodium and N- sodium lauroyl sarcosine and its mixture, preferably N- sodium lauroyl sarcosine, N- myristoyl-N-methylaminoacetic acid sodium, the N- month
Osmanthus acyl sodium glutamate, 4- aminobutanecarboxylic acid, 6- aminohexanecarboxylic acid, 12- aminolauric acid, one in L-Glycylglycine
Kind is several.
Further, the salt of the amino acid is sodium salt, sylvite, ammonium salt, any one in quaternary ammonium salt.
Further, by pearl powder: water=(10-40): the mass ratio of (60-90) weighs the pearl powder and water,
The Amino acid score powder of the 0.1%wt-2.0%wt of the pearl powder quality is added, mixing, stirring, grinding obtain pearl slurry
Material.
Further, the granularity of pearl powder is 40nm-1000nm in the pearl slurry.
Further, the Amino acid score powder be arginine polymer, lysine polymers, aspartic acid polymers,
Proline polymer, glutamic acid polymer, any one in glycine.
Further, the Amino acid score powder is serine sodium salt, threonine sylvite, is acylated in serine base hydrochlorate
Any one.
Further, the Amino acid score powder is the mixture of leucine, tyrosine, phenylalanine.
Further, in the mixture of the leucine, tyrosine, phenylalanine, leucine, tyrosine, phenylalanine
Mass ratio be 1: 0.8: 1.2.
Further, the Amino acid score powder is histidine leucine copolymer.
Further, the polymer of the amino acid is obtained by following steps:
A1. the triethanolamine of 100-200 parts by weight is added into reaction kettle, stirs, be heated to 80-120 DEG C:
A2. the gelatin of 100-150 parts by weight is added, in 80-100 DEG C of stirring and dissolving, is warming up to 100-120 DEG C, stirring is anti-
4h-8h is answered, is cooled to 60 DEG C -80 DEG C；
A3. the alkyl glycidyl ether of 100-150 parts by weight is added, is warming up to 80 DEG C, is stirred to react 8h；
A4. the deionized water of 200-800 parts by weight is added, the amino acid of 20-50 parts by weight is warming up to 80-120 DEG C, stirs
Mix reaction 4h；
A5. the acid regulator of 50-60 parts by weight is added, is warming up to 70-90 DEG C, is stirred to react 2h-4h, cooling, distillation
Water removal crushes, and drying obtains amino acid polymer；
A6. pearl powder: water=(10-40): the mass ratio of (60-90) is pressed, the pearl powder and water are weighed, adds institute
The amino acid polymer of the 0.1%wt-2.0%wt of pearl powder quality, mixing, stirring, grinding are stated, acquisition D90 is 40nm-
The pearl slurry of 1000nm；
Wherein, the alkyl glycidyl ether is alkyl glycidyl ether, lauryl diglycidyl ether, myristyl contracting
Any one in water glycerin ether, stearyl glycidyl ether；
The acid regulator is citric acid, oleic acid, any one in lauric acid；
The amino acid polymer is arginine polymer, lysine polymers, aspartic acid polymers, proline polymerization
Object, glutamic acid polymer, any one in glycine.
Further, the polymer of the amino acid is obtained by following steps:
B1. the amino acid of 120-160 parts by weight, the water of 30-50 parts by weight and 10-30 parts by weight are added into reaction kettle
Methanesulfonic acid stirs evenly；
B2., the mixture of step B1 is heated to 200 DEG C -220 DEG C of condensation temp under nitrogen protection, and in the temperature
Cooling after lower condensation 4-8 hours, distillation water removal crushes, and drying obtains amino acid polymer；
B3. pearl powder: water=(10-40): the mass ratio of (60-90) is pressed, the pearl powder and water are weighed, adds institute
The amino acid of the 0.1%wt-2.0%wt of pearl powder quality is stated, mixing, stirring, grinding, obtaining D90 is 40nm-1000nm's
Pearl slurry.
Further, the polymer of the amino acid is obtained by following steps:
C1. the amino acid of 100-120 parts by weight, the water of 50-80 parts by weight and 10-20 parts by weight are added into reaction kettle
Methanesulfonic acid stirs evenly；
C2., the mixture of step C1 is heated to 200 DEG C -220 DEG C of condensation temp under nitrogen protection, and in the temperature
Cooling after lower condensation 4-8 hours, distillation water removal crushes, and drying obtains amino acid polymer；
C3. the amino acid polymer of 100-120 parts by weight and the water of 100-120 parts by weight are mixed, is heated to 60 DEG C -80
DEG C, sodium hydroxide solution is added dropwise until pH value reaches 8-9, distillation water removal crushes, and drying obtains amino acid sodium；
C4. pearl powder: water=(10-40): the mass ratio of (60-90) is pressed, the pearl powder and water are weighed, adds institute
The amino acid sodium of the 0.1%wt-2.0%wt of pearl powder quality, mixing, stirring, grinding are stated, acquisition D90 is 40nm-
The pearl slurry of 1000nm.
Further, the polymer of the amino acid is obtained by following steps:
D1. protein: water=(10-40): protein and water are mixed, obtain polypeptide solution by the mass ratio of (60-90)；
D2. the protease of protein quality 2% is added, carries out enzyme digestion reaction 2h under stirring at 50 DEG C；
D3. citric acid is used, pH value is adjusted to 2, is stirred to react at 80 DEG C, during which maintenance system pH is not higher than 2.5；
D4. it is cooled to room temperature DEG C, the active carbon that protein quality 0.1% is added carries out absorption 60min, is then filtered to remove
Active carbon obtains amino acid and amino acid oligopeptide complex liquid；
D5. amino acid and amino acid oligopeptide complex liquid are cooled to 5~10 DEG C；Pair of protein quality 0.3% is added
Toluenesulfonic acid, is added dropwise 3 times of protein quality of caprylyl chloride under stirring, while with sodium hydroxide by the pH value of reaction system
Maintain 10；After caprylyl chloride is added dropwise, 40 DEG C are warming up to, the reaction was continued 3h obtains acylated amino group acid sodium-salt；
D6. under stirring, citric acid is added dropwise by the pH value of acylated amino group acid sodium-salt and is adjusted to 3, is used after collecting precipitating
The washing of ethanol-acetone solution, it is dry, obtain filter cake；
D7. filter cake and water being mixed, is warming up to 50 DEG C, after stirring and evenly mixing, be added dropwise to sodium carbonate to neutrality, distillation removes water,
It crushes, drying obtains acylated amino group acidic group hydrochlorate；
D8. pearl powder: water=(10-40): the mass ratio of (60-90) is pressed, the pearl powder and water are weighed, adds institute
The acylation serine base hydrochlorate of the 0.1%wt-2.0%wt of pearl powder quality is stated, mixing, stirring, grinding, obtaining D90 is
The pearl slurry of 40nm-1000nm.
A kind of pearl slurry containing Amino acid score powder, using the system of the pearl slurry containing Amino acid score powder
Preparation Method obtains.
Compared with prior art, the present invention the advantage is that: the present invention added in pearl slurry it is safe and reliable, especially may be used
Edible dispersing agent improves its security performance while guaranteeing pearl slurry dispersion performance, can be applied to food, medicine
The fields such as product, health care product.
Specific embodiment
The embodiment of the invention provides a kind of preparation method of pearl slurry containing Amino acid score powder, the pearl slurry
Material uses the raw material comprising pearl powder and water, further includes Amino acid score powder in the raw material.The Amino acid score powder is
At least one of amino acid, the polymer of amino acid or salt of amino acid.The salt of the amino acid be sodium salt, sylvite, ammonium salt,
Any one in quaternary ammonium salt.The additive amount of the Amino acid score powder is the 0.1%wt-2.0% of the pearl powder quality
wt.The amino acid is aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, cystine, figured silk fabrics ammonia
One or more of acid, methionine, isoleucine, leucine, tyrosine, phenylalanine, lysine, histidine, arginine.
The specific preparation step of the pearl slurry containing Amino acid score powder of the embodiment of the present invention are as follows: press pearl powder:
Water=(10-40): the mass ratio of (60-90) weighs the pearl powder and water, adds the 0.1% of the pearl powder quality
The Amino acid score powder of wt-2.0%wt, mixing, stirring, grinding, obtains pearl slurry.In part preferred implementation side of the invention
In formula, the mass ratio of the pearl powder and water is pearl powder: water=(20-30): (70-80).It is precious in the pearl slurry
The granularity of pearl powder is 40nm-1000nm.
Embodiment 1
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
A1. the triethanolamine of 150 parts by weight is added into reaction kettle, stirs, be heated to 80 DEG C；
A2. the gelatin of 100 parts by weight is added, in 90 DEG C of stirring and dissolvings, is warming up to 120 DEG C, is stirred to react 8h, be cooled to 80
℃；
A3. the decyl glycidyl ether of 100 parts by weight is added, is warming up to 80 DEG C, is stirred to react 8h；
A4. the deionized water of 400 parts by weight is added, the arginine of 30 parts by weight is warming up to 80 DEG C, is stirred to react 4h；
A5. the citric acid of 50 parts by weight is added, is warming up to 80 DEG C, is stirred to react 2h, cooling, distillation water removal is crushed, dried
It is dry, obtain arginine polymer；
A6. press pearl powder: water=40: 60 mass ratio weighs the pearl powder and water, adds the pearl powder
The arginine polymer of the 0.2%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 2
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
A1. the triethanolamine of 100 parts by weight is added into reaction kettle, stirs, be heated to 90 DEG C；
A2. the gelatin of 1500 parts by weight is added, in 100 DEG C of stirring and dissolvings, is warming up to 130 DEG C, is stirred to react 6h, be cooled to
90℃；
A3. the lauryl diglycidyl ether of 150 parts by weight is added, is warming up to 90 DEG C, is stirred to react 6h；
A4. the deionized water of 500 parts by weight is added, the lysine of 40 parts by weight is warming up to 90 DEG C, is stirred to react 6h；
A5. the lauric acid of 40 parts by weight is added, is warming up to 90 DEG C, is stirred to react 2h, cooling, distillation water removal is crushed, dried
It is dry, obtain lysine polymers；
A6. press pearl powder: water=30: 70 mass ratio weighs the pearl powder and water, adds the pearl powder
The lysine polymers of the 0.8%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 3
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
A1. the triethanolamine of 200 parts by weight is added into reaction kettle, stirs, be heated to 80 DEG C；
A2. the gelatin of 100 parts by weight is added, in 75 DEG C of stirring and dissolvings, is warming up to 100 DEG C, is stirred to react 4h, be cooled to 70
℃；
A3. the myristyl glycidol ether of 150 parts by weight is added, is warming up to 70 DEG C, is stirred to react 8h；
A4. the deionized water of 400 parts by weight is added, the aspartic acid of 35 parts by weight is warming up to 70 DEG C, is stirred to react 4h；
A5. the oleic acid of 50 parts by weight is added, is warming up to 70 DEG C, is stirred to react 2h, cooling, distillation water removal crushes, drying,
Obtain aspartic acid polymers；
A6. press pearl powder: water=35: 65 mass ratio weighs the pearl powder and water, adds the pearl powder
The aspartic acid polymers of the 1.2%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 4
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
A1. the triethanolamine of 120 parts by weight is added into reaction kettle, stirs, be heated to 110 DEG C；
A2. the gelatin of 180 parts by weight is added, in 90 DEG C of stirring and dissolvings, is warming up to 110 DEG C, is stirred to react 8h, be cooled to 80
℃；
A3. the stearyl glycidyl ether of 80 parts by weight is added, is warming up to 80 DEG C, is stirred to react 8h；
A4. the deionized water of 600 parts by weight is added, the proline of 40 parts by weight is warming up to 80 DEG C, is stirred to react 4h；
A5. the citric acid of 50 parts by weight is added, is warming up to 80 DEG C, is stirred to react 2h, cooling, distillation water removal is crushed, dried
It is dry, obtain proline polymer；
A6. press pearl powder: water=20: 80 mass ratio weighs the pearl powder and water, adds the pearl powder
The proline polymer of the 1.6%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 5
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
R1. the methanesulfonic acid of the glutamic acid of 120 parts by weight, the water of 30 parts by weight and 10 parts by weight is added into reaction kettle, stirs
It mixes uniformly；
B2., the mixture of step B1 is heated to 220 DEG C of condensation temp under nitrogen protection, and is condensed at such a temperature
Cooling after 6 hours, distillation water removal crushes, and drying obtains glutamic acid polymer；
B3. press pearl powder: water=20: 80 mass ratio weighs the pearl powder and water, adds the pearl powder
The glutamic acid polymer of the 1.6%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 6
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
B1. the methanesulfonic acid of the glycine of 140 parts by weight, the water of 50 parts by weight and 10 parts by weight is added into reaction kettle, stirs
It mixes uniformly；
B2., the mixture of step R1 is heated to 200 DEG C of condensation temp under nitrogen protection, and is condensed at such a temperature
Cooling after 8 hours, distillation water removal crushes, and drying obtains glycine；
B3. press pearl powder: water=30: 70 mass ratio weighs the pearl powder and water, adds the pearl powder
The glycine of the 2%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 7
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
C1. the methanesulfonic acid of the serine of 100 parts by weight, the water of 50 parts by weight and 15 parts by weight is added into reaction kettle, stirs
It mixes uniformly；
C2., the mixture of step C1 is heated to 200 DEG C of condensation temp under nitrogen protection, and is condensed at such a temperature
Cooling after 8 hours, distillation water removal crushes, and drying obtains serine polymers；
C3. the serine polymers of 100 parts by weight and the water of 100 parts by weight are mixed, is heated to 60 DEG C, hydroxide is added dropwise
Sodium solution is until pH value reaches 9, and distillation water removal crushes, and drying obtains serine sodium salt；
C4. press pearl powder: water=30: 70 mass ratio weighs the pearl powder and water, adds the pearl powder
The serine sodium salt of the 1%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 8
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
C1. the methanesulfonic acid of the threonine of 100 parts by weight, the water of 50 parts by weight and 15 parts by weight is added into reaction kettle, stirs
It mixes uniformly；
C2., the mixture of step C1 is heated to 220 DEG C of condensation temp under nitrogen protection, and is condensed at such a temperature
Cooling after 6 hours, distillation water removal crushes, and drying obtains threonine polymer；
C3. the threonine polymer of 100 parts by weight and the water of 120 parts by weight are mixed, is heated to 60 DEG C, hydroxide is added dropwise
Potassium solution is until pH value reaches 10, and distillation water removal crushes, and drying obtains threonine sylvite；
C4. press pearl powder: water=30: 70 mass ratio weighs the pearl powder and water, adds the pearl powder
The threonine sylvite of the 1.2%wt of quality, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 9
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
D1. serine stretch protein: water=30: serine stretch protein and water are mixed, it is molten to obtain silk-fibroin polypeptide by 70 mass ratio
Liquid；
D2. the protease of serine stretch protein quality 2% is added, carries out enzyme digestion reaction 2h under stirring at 50 DEG C；
D3. citric acid is used, pH value is adjusted to 2, is stirred to react at 80 DEG C, during which maintenance system pH is not higher than 2.5；
D4. it is cooled to room temperature DEG C, the active carbon that serine stretch protein quality 0.1% is added carries out absorption 60min, then filters
Active carbon is removed, serine and serine oligopeptide complex liquid are obtained；
D5. serine and serine oligopeptide complex liquid are cooled to 5~10 DEG C；Serine stretch protein quality 0.3% is added
P-methyl benzenesulfonic acid, be added dropwise 3 times of serine stretch protein quality of caprylyl chloride under stirring, while with sodium hydroxide by reactant
The pH value of system maintains 10；After caprylyl chloride is added dropwise, 40 DEG C are warming up to, the reaction was continued 3h obtains acylated serine sodium salt；
D6. under stirring, citric acid is added dropwise by the pH value of acylated serine sodium salt and is adjusted to 3, is used after collecting precipitating
The washing of ethanol-acetone solution, it is dry, obtain filter cake；
D7. filter cake and water being mixed, is warming up to 50 DEG C, after stirring and evenly mixing, be added dropwise to sodium carbonate to neutrality, distillation removes water,
It crushes, drying, obtains acylated serine base hydrochlorate；
D8. press pearl powder: water=30: 70 mass ratio weighs the pearl powder and water, adds the pearl powder
The acylation serine base hydrochlorate of the 1.2%wt of quality, mixing, stirring, grinding obtain the pearl that D90 is 40nm-1000nm and starch
Material.
Embodiment 10
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
By pearl powder: water=40: 60 mass ratio weighs the pearl powder and water, adds the pearl powder constitution
The ispol of the 0.2%wt of amount, the ispol include the alanine that mass ratio is 1: 1: 1.5, cystine
And valine, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 11
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
By pearl powder: water=30: 70 mass ratio weighs the pearl powder and water, adds the pearl powder constitution
The ispol of the 0.6%wt of amount, the ispol include the leucine that mass ratio is 1: 0.8: 1.2, junket ammonia
Acid, phenylalanine, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Embodiment 12
In the present embodiment, the pearl slurry containing Amino acid score powder is obtained by following steps:
A1. the triethanolamine of 100 parts by weight is added into reaction kettle, stirs, be heated to 80 DEG C；
A2. the gelatin of 120 parts by weight is added, in 90 DEG C of stirring and dissolvings, is warming up to 120 DEG C, is stirred to react 8h, be cooled to 80
℃；
A3. the decyl glycidyl ether of 120 parts by weight is added, is warming up to 80 DEG C, is stirred to react 8h；
A4. the deionized water of 400 parts by weight, the histidine of 20 parts by weight is added, the leucine of 20 parts by weight is warming up to 80
DEG C, be stirred to react 4h；
A5. the citric acid of 50 parts by weight is added, is warming up to 80 DEG C, is stirred to react 2h, cooling, distillation water removal is crushed, dried
It is dry, obtain histidine leucine copolymer；
A6. press pearl powder: water=20: 80 mass ratio weighs the pearl powder and water, adds the pearl powder
The histidine leucine copolymer of the 0.6%wt of quality, mixing, stirring, grinding obtain the pearl that D90 is 40nm-1000nm and starch
Material.
Comparative example 1
By pearl powder: water=20: 80 mass ratio weighs the pearl powder and water, and mixing, stirring, grinding obtain
D90 is the pearl slurry of 40nm-1000nm.
Comparative example 2
By pearl powder: water=40: 60 mass ratio weighs the pearl powder and water, adds the pearl powder constitution
The calgon of the 0.6%wt of amount, mixing, stirring, grinding obtain the pearl slurry that D90 is 40nm-1000nm.
Performance test
In order to assess amino acid, the amino acid polymer, amino acid composition, amino acid of 1-12 of embodiment of the present invention preparation
Salt, to the raising degree of the dispersion performance of pearl powder, the present invention measures characterization embodiment 1-12 and comparative example by zeta potential
The dispersibility for the pearl slurry that 1-2 is obtained and the dispersion stabilization of medium-term and long-term placement.
Zeta potential is the measurement of the surface charge of particle.Zeta potential refers to particle/electrolyte electrochemical in dispersion
Current potential on the level of shear face of double-layer inner.When zeta potential absolute value is too small, repulsive force cannot offset the Van der Waals of particle
Power, therefore particle can occur flocculation and may settle.Under certain ph, zeta potential absolute value is bigger, and dispersion is more stable.Zeta potential
It is measured by electrokinetic sound amplitude.
Table 1 lists ζ of the pearl slurry of embodiment 1-12 and comparative example 1-2 acquisition under conditions of pH value is 9.5
Current potential.By table 1 it is found that the pearl slurry of preparation of the embodiment of the present invention has preferable dispersibility, simultaneously as the present invention adopts
Use the polymer of amino acid or amino acid as dispersing agent, therefore, pearl slurry obtained has preferable biological safety,
It can be applied in multiple fields such as food, drug, health care product, cosmetics.
Table 1
Obviously, above-described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.Based on the present invention
In embodiment, those of ordinary skill in the art without creative efforts to these embodiments carry out it is various
Variation, modification, replacement and improvement, should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of preparation method of the pearl slurry containing Amino acid score powder, the pearl slurry use comprising pearl powder and
The raw material of water, is obtained by mixed grinding, which is characterized in that further includes Amino acid score powder in the raw material.
2. the preparation method of the pearl slurry according to claim 1 containing Amino acid score powder, which is characterized in that described
The additive amount of Amino acid score powder is the 0.1%wt-2.0%wt of the pearl powder quality.
3. the preparation method of the pearl slurry according to claim 1 containing Amino acid score powder, which is characterized in that described
The mass ratio of pearl powder and water is pearl powder: water=(10-40): (60-90).
4. the preparation method of the pearl slurry according to claim 3 containing Amino acid score powder, which is characterized in that described
The mass ratio of pearl powder and water is pearl powder: water=(20-30): (70-80).
5. the preparation method of the pearl slurry according to claim 1 containing Amino acid score powder, which is characterized in that described
Amino acid score powder is at least one of amino acid, the polymer of amino acid or salt of amino acid.
6. the preparation method of the pearl slurry according to claim 5 containing Amino acid score powder, which is characterized in that described
Amino acid is aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, cystine, valine, egg ammonia
One or more of acid, isoleucine, leucine, tyrosine, phenylalanine, lysine, histidine, arginine.
7. the preparation method of the pearl slurry according to claim 5 containing Amino acid score powder, which is characterized in that described
The salt of amino acid is sodium salt, sylvite, ammonium salt, any one in quaternary ammonium salt.
8. the preparation method of the pearl slurry according to claim 1 containing Amino acid score powder, which is characterized in that by treasure
Pearl powder: water=(10-40): the mass ratio of (60-90) weighs the pearl powder and water, adds the pearl powder quality
0.1%wt-2.0%wt Amino acid score powder, mixing, stirring, grinding, obtain pearl slurry.
9. the preparation method of the pearl slurry according to claim 8 containing Amino acid score powder, which is characterized in that described
The granularity of pearl powder is 40nm-1000nm in pearl slurry.
10. a kind of pearl slurry containing Amino acid score powder, which is characterized in that using any one of claim 1-9 institute
The preparation method for stating the pearl slurry containing Amino acid score powder obtains.
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