CN110495907A - A kind of pathological changes diagnosis system based on ultrasound grayscale ratio - Google Patents
A kind of pathological changes diagnosis system based on ultrasound grayscale ratio Download PDFInfo
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- CN110495907A CN110495907A CN201910803433.3A CN201910803433A CN110495907A CN 110495907 A CN110495907 A CN 110495907A CN 201910803433 A CN201910803433 A CN 201910803433A CN 110495907 A CN110495907 A CN 110495907A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5207—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/58—Testing, adjusting or calibrating the diagnostic device
- A61B8/585—Automatic set-up of the device
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Abstract
The embodiment of the invention discloses a kind of pathological changes diagnosis systems based on ultrasound grayscale ratio, it include: ultrasonic scanning module, image conversion module, computing module and comparison module, the ultrasonic scanning module scans patient diseased region and normal person's same area, change operator and ultrasonic instrument type during the scanning process, adjust ultrasonic probe frequency, image gain, time bias gain and dynamic range values, obtain the ultrasound grayscale figure under different condition, ultrasound grayscale figure is converted ultrasound grayscale value by described image conversion module, the computing module calculates the ratio of the ultrasound grayscale value of diseased region and the ultrasound grayscale value of normal portions, obtain ultrasound grayscale ratio, the ultrasound grayscale ratio obtained under different condition and diseased region standard gray scale ratio are compared the comparison module, filter out optimal ultrasonic scanning condition.The present invention solves the problems, such as that existing ultrasound diagnosis can not precisely judge whether organ occurs lesion.
Description
Technical field
The present embodiments relate to ultrasound image processing technology fields, and in particular to a kind of disease based on ultrasound grayscale ratio
Become diagnostic system.
Background technique
Complete, adaptation is wide, intuitive, repeatable, spirit strong to soft tissue taste due to having for Medical ultrasound image technology
The advantages that living and inexpensive, so occupying particularly important status in INVENTIONModern diagnostic techniques.B-mode ultrasonography equipment is that one kind makes
With medical imaging devices in extensive range, technology is highly developed.
Standardize in the case where ultrasonic scanning, the grayscale value and same level for obtaining diseased region by gray scale histogram are just
The grayscale value of normal parathyroid tissue, and calculate lesion grayscale value/parathyroid tissue grayscale value ratio, as the result is shown ultrasound grayscale ratio
Value is in small papillary carcinoma, micronodule goitre, the small papillary carcinoma of extremely low echo and echoless nodositas thyroid gland
Important value is all had in swollen antidiastole.Diagnosis effect than existing diagnostic techniques is good, but existing different machines are imaged
Quality it is different, the obese degree of different gimmicks that doctor uses during the inspection process, different dynamics and patient all can be right
Measured value generates different degrees of influence, causes diagnostic result inaccurate.
Summary of the invention
For this purpose, the embodiment of the present invention provides a kind of pathological changes diagnosis system based on ultrasound grayscale ratio, it is existing super to solve
Audio clinic can not precisely judge the problem of whether organ occurs lesion.
To achieve the goals above, the embodiment of the present invention provides the following technical solutions:
The embodiment of the invention discloses a kind of pathological changes diagnosis system based on ultrasound grayscale ratio, the system comprises: it is super
Sound scan module, image conversion module, computing module and comparison module, the ultrasonic scanning module scans patient diseased region and
Normal person's same area changes operator and ultrasonic instrument type during the scanning process, adjusts ultrasonic probe frequency, image increasing
Benefit, time bias gain and dynamic range values obtain the ultrasound grayscale figure under different condition, and described image conversion module will be ultrasonic
Gray-scale figure is converted into ultrasound grayscale value, and the computing module calculates the ultrasound grayscale value of diseased region and the ultrasound ash of normal portions
The ratio of rank value obtains ultrasound grayscale ratio, the ultrasound grayscale ratio and lesion that the comparison module will obtain under different condition
Part standard grayscale ratio is compared, and filters out optimal ultrasonic scanning condition.
Further, the ultrasonic scanning module includes ultrasound scanner, and the ultrasound scanner is in scanning diseased region
When, tubercle uniform for echo is chosen and is greater than half knuckle area for ultrasound scanner area-of-interest, for echo
Non-uniform tubercle, choose echo in the highest region of accounting be main measured zone, choose in main measured zone be greater than two/
One knuckle area is ultrasound scanner area-of-interest.
Further, it when the ultrasound scanner scanning normal organ tissue, chooses and the same transverse direction of diseased organ tubercle
Horizontal zone and an equal amount of ultrasound scanner area-of-interest.
Further, the ultrasonic scanning instrument is during the scanning process to frequency probe, image gain, time bias gain
It is adjusted with dynamic range values, changes a variable every time, obtain the ultrasound of unitary variant under three different conditions respectively
Gray-scale figure.
Further, described image conversion module denoises ultrasound grayscale figure, converts ultrasound grayscale figure after denoising
For gray scale histogram, the data after gray scale histogram is equalized are according to rule filling look-up table, according to the corresponding number of look-up table
Value obtains ultrasound grayscale value.
Further, the comparison module according to ultrasound scanner change operation doctor, scanner, frequency probe,
The different ultrasonic grayscale ratios obtained under conditions of image gain, time bias gain and dynamic range values, and make a definite diagnosis lesion device
The scanning ultrasonic grayscale ratio of official compares, and filters out optimal scanner, frequency probe value, image according to comparing result
Yield value, time bias value and dynamic range values.
Further, the computing module is grey by the normal ultrasound of ultrasound grayscale value and same area that diseased region occurs
Rank value asks quotient, obtains ultrasonic grayscale ratio, is made a definite diagnosis according to ultrasonic grayscale ratio diseased region.
Further, the computing module establishes measured database according to calculated ultrasonic grayscale ratio, to measurement number
Multicenter external certificate, clinical diagnosis result are carried out according to the data in library.
The embodiment of the present invention has the advantages that
The embodiment of the invention discloses a kind of pathological changes diagnosis systems based on ultrasound grayscale ratio, are swept by ultrasound scanner
Retouch diseased region and normal portions obtain ultrasound grayscale figure, change operation doctor, scanner, frequency probe, image gain, when
Between compensating gain and dynamic range values obtain different ultrasound grayscale figures, ultrasound grayscale figure is converted into ultrasound grayscale value, is calculated
Ultrasonic grayscale ratio, carries out according to the ultrasound grayscale ratio under different condition with the ultrasound grayscale ratio for making a definite diagnosis diseased organ pair
Than, determine the optimal condition of scanning, make ultrasonic scanning diagnosis can quantitative criteria, keep diagnostic result more accurate.And pass through
The ultrasound grayscale value of diseased organ and the ultrasound grayscale value of normal homolog carry out the method that ratio obtains ultrasound grayscale ratio,
The blank for having filled up the diagnosis of this field ultrasound, can more accurately diagnose the state of an illness by ultrasound grayscale ratio.
Detailed description of the invention
It, below will be to embodiment party in order to illustrate more clearly of embodiments of the present invention or technical solution in the prior art
Formula or attached drawing needed to be used in the description of the prior art are briefly described.It should be evident that the accompanying drawings in the following description is only
It is merely exemplary, it for those of ordinary skill in the art, without creative efforts, can also basis
The attached drawing of offer, which is extended, obtains other implementation attached drawings.
Structure depicted in this specification, ratio, size etc., only to cooperate the revealed content of specification, for
Those skilled in the art understands and reads, and is not intended to limit the invention enforceable qualifications, therefore does not have technical
Essential meaning, the modification of any structure, the change of proportionate relationship or the adjustment of size are not influencing the function of the invention that can be generated
Under effect and the purpose that can reach, should all still it fall in the range of disclosed technology contents obtain and can cover.
Fig. 1 is a kind of pathological changes diagnosis system flow chart based on ultrasound grayscale ratio provided in an embodiment of the present invention；
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book is understood other advantages and efficacy of the present invention easily, it is clear that described embodiment is the present invention one
Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing
Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.
Embodiment
Present embodiment discloses a kind of pathological changes diagnosis systems based on ultrasound grayscale ratio, comprising: ultrasonic scanning module, figure
As conversion module, computing module and comparison module, the ultrasonic scanning module scans patient diseased region and normal person's identical portions
Position changes operator and ultrasonic instrument type during the scanning process, adjusts ultrasonic probe frequency, image gain, time bias increasing
Benefit and dynamic range values, obtain the ultrasound grayscale figure under different condition, and described image conversion module converts ultrasound grayscale figure to
Ultrasound grayscale value, the computing module calculate the ratio of the ultrasound grayscale value of diseased region and the ultrasound grayscale value of normal portions,
Obtain ultrasound grayscale ratio, the comparison module is by the ultrasound grayscale ratio obtained under different condition and diseased region standard gray scale
Ratio is compared, and filters out optimal ultrasonic scanning condition.
Ultrasonic scanning module includes ultrasound scanner, and the ultrasound scanner is equal for echo when scanning diseased region
Even tubercle, choose be greater than half knuckle area be ultrasound scanner area-of-interest, the tubercle even for Echo heterogenicity,
Choose echo in the highest region of accounting be main measured zone, choose in main measured zone be greater than half knuckle area be super
Sound scanner area-of-interest；
Ultrasound scanner area-of-interest (Region of interest, abbreviation ROI), in machine vision, image procossing,
Region to be treated is sketched the contours of in a manner of box, circle, ellipse, irregular polygon etc. from processed image, is referred to as felt
Interest region, in the present embodiment, ultrasound scanner choose echo it is more obvious, convenient for crawl region as ultrasound scanner
Area-of-interest, convenient for generating clearly ultrasound grayscale image.When ultrasound scanner scans normal organ tissue, selection and lesion
The same transversely and horizontally region of organ tubercle and an equal amount of ultrasound scanner area-of-interest, are convenient for comparing, and reduce not
Necessary interference.
Unqualified case is discharged using prospective method in the present embodiment, chooses 200 thyroid gland sufferers, including benign
Example 100, pernicious case 100 selects two different ultrasound scanners of A, B, and operation doctor chooses two doctor of first, second,
Position, which is dorsal position, to be checked to patient, head, which is swung back, exposes anterior cervical region, and scan method is longitudinal sectional and crosscutting using standard, in lesion
Maximum level carries out Image Acquisition.First doctor carries out routine examination to lesion using A ultrasound scanner, during the scanning process to spy
Head frequency, image gain, time bias gain and dynamic range values are adjusted, and change a variable every time, obtain respectively single
The ultrasound grayscale of one variable under three different conditions；Second doctor repeats operation identical with first doctor using A ultrasound scanner,
In one week, first and two doctor of second carry out identical inspection to 200 sufferers again on B ultrasound sound scanner and operate.Wherein, it moves
The definition of state range: system can check, the ratio between peak signal correspondence and minimum signal for handling or show, dynamic model
Enclose=maximum echo amplitude/minimum echo amplitude.
Inspection terminates, and obtains multiple ultrasound grayscale figures, and image conversion module denoises ultrasound grayscale figure, will after denoising
Ultrasound grayscale figure is converted into gray scale histogram, and the data after gray scale histogram is equalized insert look-up table according to rule, according to
The corresponding numerical value of look-up table obtains ultrasound grayscale value；
Adaptive grey level mapping method for ultrasonic image of the present invention encodes the histogram treatment of image with according to gray scale curve
Grayscale mapping is carried out to combine.Grayscale mapping in the present invention is realized by two look-up tables.User selects grayscale
Adaptive coding, the grayscale adaptive coding that software is selected according to user carry out histogram equalization to current image data,
Acquire first order look-up table.User selects gray scale curve coding, and the gray scale curve coding that software is selected according to user acquires second
Grade look-up table.Two look-up tables are descended into FPGA, image data first acquires median, median according to first order look-up table
Display data are acquired further according to second level look-up table.
The first order or second level look-up table can be closed according to the user's choice.First order look-up table is closed to be equivalent to only
Using gray scale curve, and closes second level look-up table and be equivalent to that only use grayscale adaptive.Grayscale adaptive coding in the present invention
Totally 2 kinds, wherein 0 is closing, 1 is opening.And gray scale curve is encoded to 17 kinds, wherein 0 is closing, 1-16 is 16 kinds of different ashes
Rank curve.The grayscale adaptive coding selected in the present invention according to user carries out at histogram equalization, with usual digital picture
Algorithm in reason is essentially identical.Unlike unique, the histogram treatment of image is carried out for single image, is directly changed
The value of its image data.And the histogram treatment in the present invention be first according to selection grayscale adaptation function when current figure
Picture carries out histogram treatment to it, acquire a look-up table, and directly counts to image data thereafter by searching for table
It calculates.This is primarily due to each image and all carries out histogram calculation, and it is too big to will lead to calculation amount, and in B ultrasound imaging, it scans same
The image of position in tonal range and intensity profile relatively.In the present invention, histogram equalization calculating is first passed through, is made straight
Square figure is evenly distributed within whole grey-scale ranges；Gray scale curve mapping is carried out to image again, to make grey-scale range interested
It is more prominent.
Comparison module is changing operation doctor, scanner, frequency probe, image gain, time according to ultrasound scanner
The different ultrasonic grayscale ratios obtained under conditions of compensating gain and dynamic range values, with the scanning ultrasound ash for making a definite diagnosis diseased organ
Degree ratio compares, and filters out optimal scanner, frequency probe value, image gain value, time benefit according to comparing result
Repay value and dynamic range values.Make ultrasonic scanning diagnosis can quantitative criteria, keep diagnostic result more accurate.
The ultrasound grayscale value that diseased region occurs and the normal ultrasound grayscale value of same area are asked quotient by computing module, are obtained
Ultrasonic grayscale ratio makes a definite diagnosis diseased region according to ultrasonic grayscale ratio, and computing module is according to calculated ultrasonic grayscale
Ratio establishes measured database, carries out multicenter external certificate to the data in measured database, several doctors are according to ultrasonic ash
Degree ratio and practical diagnostic result are matched, and clinical diagnosis mentions as a result, help to establish complete ultrasonic scanning diagnostic system
Rise accuracy rate of diagnosis.
A kind of pathological changes diagnosis system based on ultrasound grayscale ratio disclosed by the embodiments of the present invention, is swept by ultrasound scanner
Retouch diseased region and normal portions obtain ultrasound grayscale figure, change operation doctor, scanner, frequency probe, image gain, when
Between compensating gain and dynamic range values obtain different ultrasound grayscale figures, ultrasound grayscale figure is converted into ultrasound grayscale value, is calculated
Ultrasonic grayscale ratio, carries out according to the ultrasound grayscale ratio under different condition with the ultrasound grayscale ratio for making a definite diagnosis diseased organ pair
Than, determine the optimal condition of scanning, make ultrasonic scanning diagnosis can quantitative criteria, keep diagnostic result more accurate.And pass through
The ultrasound grayscale value of diseased organ and the ultrasound grayscale value of normal homolog carry out the method that ratio obtains ultrasound grayscale ratio,
The blank for having filled up the diagnosis of this field ultrasound, can more accurately diagnose the state of an illness by ultrasound grayscale ratio.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (8)
1. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio, which is characterized in that the system comprises: ultrasonic scanning mould
Block, image conversion module, computing module and comparison module, the ultrasonic scanning module scans patient diseased region and normal person's phase
Same position changes operator and ultrasonic instrument type during the scanning process, adjusts ultrasonic probe frequency, image gain, time benefit
Gain and dynamic range values are repaid, the ultrasound grayscale figure under different condition is obtained, described image conversion module turns ultrasound grayscale figure
Ultrasound grayscale value is turned to, the computing module calculates the ratio of the ultrasound grayscale value of diseased region and the ultrasound grayscale value of normal portions
Value, obtains ultrasound grayscale ratio, and the comparison module is by the ultrasound grayscale ratio obtained under different condition and diseased region standard
Grayscale ratio is compared, and filters out optimal ultrasonic scanning condition.
2. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as described in claim 1, which is characterized in that the ultrasound
Scan module includes ultrasound scanner, and the ultrasound scanner is when scanning diseased region, tubercle uniform for echo, is chosen
It is ultrasound scanner area-of-interest greater than half knuckle area, the tubercle even for Echo heterogenicity is chosen in echo and accounted for
It is main measured zone than highest region, chooses emerging for ultrasound scanner sense greater than half knuckle area in main measured zone
Interesting region.
3. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as claimed in claim 2, which is characterized in that the ultrasound
When scanner scanning normal organ tissue, selection is swept with the same transversely and horizontally region of diseased organ tubercle and an equal amount of ultrasound
Retouch instrument area-of-interest.
4. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as claimed in claim 2, which is characterized in that the ultrasound
Scanner is during the scanning process adjusted frequency probe, image gain, time bias gain and dynamic range values, every time
Change a variable, obtains the ultrasound grayscale figure of unitary variant under three different conditions respectively.
5. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as described in claim 1, which is characterized in that described image
Conversion module denoises ultrasound grayscale figure, converts gray scale histogram for ultrasound grayscale figure after denoising, by gray scale histogram
Data after equalization obtain ultrasound grayscale value according to the corresponding numerical value of look-up table according to rule filling look-up table.
6. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as described in claim 1, which is characterized in that the comparison
Module is changing operation doctor, scanner, frequency probe, image gain, time bias gain and is moving according to ultrasound scanner
The different ultrasonic grayscale ratios obtained under conditions of state value range, carry out pair with the scanning ultrasonic grayscale ratio for making a definite diagnosis diseased organ
Than filtering out optimal scanner, frequency probe value, image gain value, time bias value and dynamic model according to comparing result
Enclose value.
7. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as described in claim 1, which is characterized in that the calculating
The ultrasound grayscale value that diseased region occurs and the normal ultrasound grayscale value of same area are asked quotient by module, obtain ultrasonic grayscale ratio
Rate makes a definite diagnosis diseased region according to ultrasonic grayscale ratio.
8. a kind of pathological changes diagnosis system based on ultrasound grayscale ratio as described in claim 1, which is characterized in that the calculating
Module establishes measured database according to calculated ultrasonic grayscale ratio, carries out outside multicenter to the data in measured database
Verifying, clinical diagnosis result.
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| CN105232081A (en) * | 2014-07-09 | 2016-01-13 | 无锡祥生医学影像有限责任公司 | Medical ultrasound assisted automatic diagnosis device and medical ultrasound assisted automatic diagnosis method |
| CN106580368A (en) * | 2016-11-26 | 2017-04-26 | 汕头市超声仪器研究所有限公司 | Full-automatic ultrasonic diagnosis method |
| CN106880378A (en) * | 2015-12-03 | 2017-06-23 | 美国西门子医疗解决公司 | The user interface based on image for controlling medical imaging |
-
2019
- 2019-08-28 CN CN201910803433.3A patent/CN110495907A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232081A (en) * | 2014-07-09 | 2016-01-13 | 无锡祥生医学影像有限责任公司 | Medical ultrasound assisted automatic diagnosis device and medical ultrasound assisted automatic diagnosis method |
| CN106880378A (en) * | 2015-12-03 | 2017-06-23 | 美国西门子医疗解决公司 | The user interface based on image for controlling medical imaging |
| CN106580368A (en) * | 2016-11-26 | 2017-04-26 | 汕头市超声仪器研究所有限公司 | Full-automatic ultrasonic diagnosis method |
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Application publication date: 20191126 |