CN110494893B - 基于ffr的对非侵入性成像的交互监测 - Google Patents

基于ffr的对非侵入性成像的交互监测 Download PDF

Info

Publication number
CN110494893B
CN110494893B CN201880023385.XA CN201880023385A CN110494893B CN 110494893 B CN110494893 B CN 110494893B CN 201880023385 A CN201880023385 A CN 201880023385A CN 110494893 B CN110494893 B CN 110494893B
Authority
CN
China
Prior art keywords
traffic light
centerline
light engine
simulation
features
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201880023385.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN110494893A (zh
Inventor
M·P·弗赖曼
L·戈申
D·B·麦克奈特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips NV filed Critical Koninklijke Philips NV
Publication of CN110494893A publication Critical patent/CN110494893A/zh
Application granted granted Critical
Publication of CN110494893B publication Critical patent/CN110494893B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026Measuring blood flow
    • A61B5/029Measuring blood output from the heart, e.g. minute volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/46Arrangements for interfacing with the operator or the patient
    • A61B6/467Arrangements for interfacing with the operator or the patient characterised by special input means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/507Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54Control of apparatus or devices for radiation diagnosis
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/12Edge-based segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/149Segmentation; Edge detection involving deformable models, e.g. active contour models
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/40ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10081Computed x-ray tomography [CT]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20092Interactive image processing based on input by user
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30101Blood vessel; Artery; Vein; Vascular
    • G06T2207/30104Vascular flow; Blood flow; Perfusion
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30172Centreline of tubular or elongated structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Optics & Photonics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Primary Health Care (AREA)
  • Hematology (AREA)
  • Quality & Reliability (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Vascular Medicine (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Software Systems (AREA)
  • Human Computer Interaction (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Image Analysis (AREA)
CN201880023385.XA 2017-03-31 2018-03-05 基于ffr的对非侵入性成像的交互监测 Active CN110494893B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762479694P 2017-03-31 2017-03-31
US62/479,694 2017-03-31
US201762545599P 2017-08-15 2017-08-15
US62/545,599 2017-08-15
PCT/EP2018/055366 WO2018177692A1 (en) 2017-03-31 2018-03-05 Interaction monitoring of non-invasive imaging based ffr

Publications (2)

Publication Number Publication Date
CN110494893A CN110494893A (zh) 2019-11-22
CN110494893B true CN110494893B (zh) 2024-01-23

Family

ID=61581301

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880023385.XA Active CN110494893B (zh) 2017-03-31 2018-03-05 基于ffr的对非侵入性成像的交互监测

Country Status (5)

Country Link
US (1) US11523744B2 (cg-RX-API-DMAC7.html)
EP (1) EP3602485B1 (cg-RX-API-DMAC7.html)
JP (1) JP7426824B2 (cg-RX-API-DMAC7.html)
CN (1) CN110494893B (cg-RX-API-DMAC7.html)
WO (1) WO2018177692A1 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10210956B2 (en) 2012-10-24 2019-02-19 Cathworks Ltd. Diagnostically useful results in real time
JP7036742B2 (ja) 2016-05-16 2022-03-15 キャスワークス リミテッド 血管評価システム
EP4241694A3 (en) 2016-05-16 2023-12-20 Cathworks Ltd. Selection of vascular paths from images
WO2020201942A1 (en) 2019-04-01 2020-10-08 Cathworks Ltd. Methods and apparatus for angiographic image selection
EP4033964B1 (en) 2019-09-23 2025-04-09 Cathworks Ltd. Methods, apparatus, and system for synchronization between a three-dimensional vascular model and an imaging device
US12315076B1 (en) 2021-09-22 2025-05-27 Cathworks Ltd. Four-dimensional motion analysis of a patient's coronary arteries and myocardial wall
US11980492B2 (en) * 2021-11-05 2024-05-14 GE Precision Healthcare LLC System and method for deep-learning based estimation of coronary artery pressure drop
WO2023152688A1 (en) 2022-02-10 2023-08-17 Cathworks Ltd. System and method for machine-learning based sensor analysis and vascular tree segmentation
US12446965B2 (en) 2023-08-09 2025-10-21 Cathworks Ltd. Enhanced user interface and crosstalk analysis for vascular index measurement
US20250380913A1 (en) 2024-06-12 2025-12-18 Cathworks Ltd. Systems and methods for displaying distal fractional flow reserve values in vascular analysis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105190630A (zh) * 2013-01-15 2015-12-23 凯瑟沃克斯有限公司 计算血流储备分数
CN105184086A (zh) * 2014-06-16 2015-12-23 西门子公司 用于冠状动脉中改进的血液动力学计算的方法及系统
CN106163388A (zh) * 2014-03-31 2016-11-23 皇家飞利浦有限公司 用于处理生命体的心脏数据的处理装置和方法
CN106539622A (zh) * 2017-01-28 2017-03-29 北京欣方悦医疗科技有限公司 基于血流动力学分析的冠脉虚拟支架植入方法和系统

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8442280B2 (en) * 2004-01-21 2013-05-14 Edda Technology, Inc. Method and system for intelligent qualitative and quantitative analysis of digital radiography softcopy reading
US7940974B2 (en) * 2006-11-21 2011-05-10 General Electric Company Method and system for adjusting 3D CT vessel segmentation
CN102834847B (zh) * 2010-04-13 2016-09-07 皇家飞利浦电子股份有限公司 图像分析
US8315812B2 (en) * 2010-08-12 2012-11-20 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US9119540B2 (en) * 2010-09-16 2015-09-01 Siemens Aktiengesellschaft Method and system for non-invasive assessment of coronary artery disease
US10373700B2 (en) 2012-03-13 2019-08-06 Siemens Healthcare Gmbh Non-invasive functional assessment of coronary artery stenosis including simulation of hyperemia by changing resting microvascular resistance
BR112014028143A2 (pt) 2012-05-14 2017-06-27 Koninklijke Philips Nv sistema e meio de armazenamento legível por computador
KR20140015079A (ko) 2012-07-27 2014-02-06 삼성전자주식회사 중심선을 보정하는 방법 및 장치
US9675301B2 (en) * 2012-10-19 2017-06-13 Heartflow, Inc. Systems and methods for numerically evaluating vasculature
RU2015121362A (ru) 2012-11-06 2016-12-27 Конинклейке Филипс Н.В. Индекс фракционного резерва кровотока (фрк)
JP6091870B2 (ja) * 2012-12-07 2017-03-08 東芝メディカルシステムズ株式会社 血管解析装置、医用画像診断装置、血管解析方法、及び血管解析プログラム
US8824752B1 (en) 2013-03-15 2014-09-02 Heartflow, Inc. Methods and systems for assessing image quality in modeling of patient anatomic or blood flow characteristics
CN108992058A (zh) * 2013-07-30 2018-12-14 哈特弗罗公司 为优化诊断性能利用边界条件模型化血流的方法和系统
CN105474264B (zh) * 2013-08-21 2019-08-06 皇家飞利浦有限公司 用于交互地分割在血管造影图像数据中的血管的分割装置
WO2015048196A1 (en) 2013-09-25 2015-04-02 Heartflow, Inc. Systems and methods for validating and correcting automated medical image annotations
US9905008B2 (en) * 2013-10-10 2018-02-27 University Of Rochester Automated fundus image field detection and quality assessment
US10595806B2 (en) 2013-10-22 2020-03-24 Koninklijke Philips N.V. Fractional flow reserve (FFR) index with adaptive boundary condition parameters
JP6340815B2 (ja) 2014-02-19 2018-06-13 カシオ計算機株式会社 プログラム
US9087147B1 (en) * 2014-03-31 2015-07-21 Heartflow, Inc. Systems and methods for determining blood flow characteristics using flow ratio
US10258303B2 (en) 2014-06-30 2019-04-16 Koninklijke Philips N.V. Apparatus for determining a fractional flow reserve value
US9888968B2 (en) * 2014-07-22 2018-02-13 Siemens Healthcare Gmbh Method and system for automated therapy planning for arterial stenosis
US9785748B2 (en) * 2015-07-14 2017-10-10 Heartflow, Inc. Systems and methods for estimating hemodynamic forces acting on plaque and monitoring patient risk
US11031136B2 (en) 2015-08-05 2021-06-08 Koninklijke Philips N.V. Assistance device and method for an interventional hemodynamic measurement
CN108348206B (zh) 2015-11-05 2022-07-29 皇家飞利浦有限公司 用于无创血流储备分数(ffr)的侧支流建模
CN109996495B (zh) 2016-11-22 2023-04-28 皇家飞利浦有限公司 用于生物物理模拟的血管树标准化和/或用于经修剪的部分的扩展模拟
US10163209B2 (en) * 2016-11-23 2018-12-25 Toshiba Medical Systems Corporation Medical image processing apparatus, medical image processing method, and X-ray CT apparatus
CN110506293B (zh) 2017-03-31 2023-11-07 皇家飞利浦有限公司 谱成像ffr

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105190630A (zh) * 2013-01-15 2015-12-23 凯瑟沃克斯有限公司 计算血流储备分数
CN106163388A (zh) * 2014-03-31 2016-11-23 皇家飞利浦有限公司 用于处理生命体的心脏数据的处理装置和方法
CN105184086A (zh) * 2014-06-16 2015-12-23 西门子公司 用于冠状动脉中改进的血液动力学计算的方法及系统
CN106539622A (zh) * 2017-01-28 2017-03-29 北京欣方悦医疗科技有限公司 基于血流动力学分析的冠脉虚拟支架植入方法和系统

Also Published As

Publication number Publication date
JP2020515337A (ja) 2020-05-28
US20200037893A1 (en) 2020-02-06
US11523744B2 (en) 2022-12-13
JP7426824B2 (ja) 2024-02-02
CN110494893A (zh) 2019-11-22
EP3602485B1 (en) 2023-10-11
WO2018177692A1 (en) 2018-10-04
EP3602485A1 (en) 2020-02-05

Similar Documents

Publication Publication Date Title
CN110494893B (zh) 基于ffr的对非侵入性成像的交互监测
US10595806B2 (en) Fractional flow reserve (FFR) index with adaptive boundary condition parameters
CN110506293B (zh) 谱成像ffr
CN110574121B (zh) 血流储备分数模拟参数的定制、校准和/或训练
JP6484760B2 (ja) 非侵襲的血流予備量比(ffr)に対する側副血流モデル化
EP3606433B1 (en) Standardized coronary artery disease metric
EP3544512B1 (en) Vascular tree standardization for biophysical simulation and/or an extension simulation for pruned portions
US12136209B2 (en) Orientation detection for 2D vessel segmentation for angio-FFR
JP2016529040A (ja) 心臓データを処理する処理装置
EP3244790B1 (en) Instantaneous wave-free ratio (ifr) computer tomography (ct)
US11039804B2 (en) Apparatus and method for determining a fractional flow reserve

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant