CN110456045A - Quick analytic instrument is immunized in electric field action film - Google Patents

Quick analytic instrument is immunized in electric field action film Download PDF

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Publication number
CN110456045A
CN110456045A CN201910788846.9A CN201910788846A CN110456045A CN 110456045 A CN110456045 A CN 110456045A CN 201910788846 A CN201910788846 A CN 201910788846A CN 110456045 A CN110456045 A CN 110456045A
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processor
detection card
electric field
slot
power supply
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CN201910788846.9A
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Chinese (zh)
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刘海波
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Individual
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention relates to the field of medical instrument technology, disclose a kind of immune quick analytic instrument of electric field action film, it include: supporting plate, probe, processor and power supply, supporting plate is equipped with the slot for being inserted into immune rapid detection card, immune rapid detection card is equipped with the circuit structure for forming electric field on reaction film, the positive electrode contact for circuit structure power-up and negative electrode contact are equipped in slot, probe is located at slot-side, for obtaining the observation window image of immune rapid detection card under the control of a processor, and observation window image is sent to processor, processor is based on image recognition and obtains analysis result, power supply is probe, positive electrode contact and negative electrode contact and processor power supply.Analyzer of the invention can generate electric field on the reaction film of immune rapid detection card, so that antigen-antibody reaction movement velocity and direction are controllable, the accuracy of testing result, repeatability and sensitivity are greatly improved, realizes and quantitative analysis quickly and effectively is carried out to detected material.

Description

Quick analytic instrument is immunized in electric field action film
Technical field
The present invention relates to the field of medical instrument technology, in particular to quick analytic instrument is immunized in a kind of electric field action film.
Background technique
Rapid detection method used in the quick analytical control field of clinical immunization includes: that gold marks, fluorescent marker is exempted from present Epidemic disease chromatographic analysis rapid detection method etc..Above two method all be use the measured object on reaction film (antigen or antibody) with The uncontrollable reaction pattern of marker (antibody or antigenic label) free movement chromatography.Due to the inhomogeneity of reaction film, no Different from quality with measured object molecule (antigen) structure, the factors such as different measured object interfering substances containing different motion lead to antigen The uncontrollable problem of antibody response movement velocity and direction, so that the poor repeatability of inspection result, inspection result accuracy Difference examines sensitivity low, hinders the development and extensive utilization examined in clinical especially clinical emergency.
Summary of the invention
The present invention proposes that quick analytic instrument is immunized in a kind of electric field action film, solves antigen-antibody reaction campaign in the prior art The uncontrollable problem of speed.
Quick analytic instrument is immunized in a kind of electric field action film of the invention, comprising: supporting plate, probe, processor and power supply, institute Supporting plate is stated equipped with the slot for being inserted into immune rapid detection card, the immune rapid detection card is equipped in reaction film The upper circuit structure for forming electric field, the interior positive electrode contact being equipped with as circuit structure power-up of the slot and negative electrode touching Point, the probe is located at the slot-side, for obtaining the observation window of immune rapid detection card under the control of a processor Image, and the observation window image is sent to the processor, the processor is based on image recognition and obtains analysis as a result, institute Stating power supply is that probe, positive electrode contact and negative electrode contact and processor are powered.
Wherein, further includes: rotation power supply mechanism, the supporting plate include: rotating disk and circuit pressing plate, and multiple slots are along rotation Disk is circumferentially uniformly distributed, and the circuit pressing plate is fixed on the rotating pan, and the region being covered on above the slot is all provided with Positive electrode contact and negative electrode contact are stated, the rotation power supply mechanism connects the power supply, circuit pressing plate and processor, the place It manages device and controls the step-length rotation by a predetermined angle of the rotation power supply mechanism driving rotating disk, so that each immune quickly detect Card is stopped in the scanning area of the probe, and is controlled probe and obtained the observation window image.
Wherein, the rotation power supply mechanism include: bearing block, support column, motor, ring gear, the first pot magnetic core and Second pot magnetic core, the ring gear are connect with bearing in bearing block, and the support column is perpendicularly fixed at bearing block bottom, with Ring gear and rotating disk coaxial arrangement;Motor connects the processor, for driving the annular under the control of a processor Gear rotation, the rotating disk are fixed on the ring gear, and the first pot magnetic core is fixed in the rotating disk, and The circuit pressing plate is connected, the second pot magnetic core is fixed on the support column, and connects the power supply, the first pot magnetic Core and the second pot magnetic core are oppositely arranged, and are spaced a predetermined distance.
Wherein, the rotation power supply mechanism includes: protective cover, and protective cover connects the rotating disk, and covers described first Pot magnetic core and the second pot magnetic core.
Wherein, the probe is also used to scan while obtaining observation window image under the control of a processor immune fast Identification code on speed detection card, reads patient information, and be uploaded to the processor, and the processor is used in immune quickly inspection It surveys card after the reaction was completed, patient information and analysis result is bound and saved.
Wherein, sensor is equipped in each slot, the sensor connects the circuit pressing plate, and being used for will be in slot Whether the signal of the immune rapid detection card of insertion is sent to the processor, and the processor is passed through in the slot calculated to non-plug-in card When over-scanning head, control rotation power supply mechanism is driven described in the rotating disk directly rotate to the slot of next plug-in card and rest on The scanning area of probe.
Wherein, further includes: detection card recovering mechanism, the detection card recovering mechanism include: recycling box, slide unit bracket, directly Line slide unit, detection card pushing hands, straight line slide unit is fixed on slide unit bracket, and connects the detection card pushing hands and processor, recycling Box is located at slide unit bracket side, and the slot bottom is equipped with the channel for passing through detection card pushing hands.
Wherein, the detection card recovering mechanism is located at below the probe.
Wherein, further includes: casing, the casing are equipped with the opening for exposing slot
Wherein, human-computer interaction module is additionally provided on the casing, the human-computer interaction module connects the processor.
Electric field action film of the invention is immunized quick analytic instrument and is equipped with just in the slot for being inserted into immune rapid detection card Electrode contacts and negative electrode contact, positive electrode contact and negative electrode contact are the circuit structure power supply of immune rapid detection card, from And electric field is generated on the reaction film of immune rapid detection card, so that antigen-antibody reaction movement velocity and direction are controllable, significantly The accuracy of testing result, repeatability and sensitivity are improved, realizes and quantitative analysis quickly and effectively is carried out to detected material.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention without any creative labor, may be used also for those of ordinary skill in the art To obtain other drawings based on these drawings.
Fig. 1 is that quick analytic instrument structural blast schematic diagram is immunized in a kind of electric field action film of the invention;
Fig. 2 is the side view of Fig. 1;
The schematic diagram after quick analytic instrument assembles is immunized in the electric field action film that Fig. 3 is Fig. 1;
Fig. 4 is the structural schematic diagram that rapid detection card is immunized in electric field action film.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
It is as shown in Figures 1 to 3 that quick analytic instrument is immunized in the electric field action film of the present embodiment, comprising: supporting plate, probe 2, processing Device and power supply, supporting plate are equipped with the slot for being inserted into immune rapid detection card 3, as shown in figure 4, in immune rapid detection card 3 Equipped with the circuit structure for forming electric field on reaction film, such as: it is equipped with positive electrode 23 and negative electrode 24, positive electrode 23 and negative Electrode 24 is separately connected the both ends of reaction film.The positive electrode contact for circuit structure power-up and negative electrode contact are equipped in slot, After immune rapid detection card 3 is inserted into slot, positive electrode contact and negative electrode contact contact positive electrode 23 and negative electrode 24 respectively.It sweeps It retouches first 2 and is located at slot-side, can be fixed on by bracket 14 right above slot, it is immune for obtaining under the control of a processor The observation window image of rapid detection card 3, and the observation item of image is sent to processor, processor are based on image recognition and obtain point Analysis is as a result, power supply is that probe 2, positive electrode contact and negative electrode contact and processor are powered.Wherein, probe 2, which can be, takes the photograph As first-class equipment, by shooting or scanning window with observation window image.
The electric field action film of the present embodiment is immunized quick analytic instrument and is equipped in the slot for being inserted into immune rapid detection card 3 Positive electrode contact and negative electrode contact, positive electrode contact and negative electrode contact are the circuit structure power supply of immune rapid detection card 3, To generate electric field on the reaction film of immune rapid detection card 3, so that antigen-antibody reaction movement velocity and direction are controllable, greatly The big accuracy for improving testing result, repeatability and sensitivity are realized and quickly and effectively carry out quantitative analysis to detected material.
In the present embodiment, as long as inserting slot construction cooperates immune 3 contour structures of rapid detection card, supporting plate be can be arbitrarily Shape, can be set one or more slots thereon, and probe 2 can shoot the immune rapid detection card in each slot in turn Observation window image, and shooting image is transmitted to processor respectively.
Quick analytic instrument is immunized in the electric field action film of the present embodiment further include: rotation power supply mechanism, supporting plate includes: rotating disk 1 and circuit pressing plate 4, multiple slots are uniformly distributed along rotating disk 1 is circumferential, and circuit pressing plate 4 is fixed in rotating disk 1, and is covered on Region above slot is equipped with positive electrode contact and negative electrode contact, rotation power supply mechanism connection power supply, circuit pressing plate 4 and place Device is managed, step-length rotates processor control rotation power supply mechanism driving rotating disk 1 by a predetermined angle, so that each immune quickly detection Card 3 is stopped the scanning area of probe 2 (such as: underface), and is controlled probe 2 and shot observation window image.Due to rotation It is provided with multiple slots on disk 1, multiple immune rapid detection cards 3 can be analyzed simultaneously, and be rotary structure, scanning First 2 need to be fixed at one, and structure is simple and compact.Rotating disk 1 is rotated by certain angle step, i.e., every rotation Predetermined angular step-length (such as: 18 slots being arranged in rotating disk 1, then predetermined angular step-length is 20 °), just has a slot sweeping It retouches with regard to short stay behind first 2 lower section, so as to the shooting of probe 2, so that each cooperate immune rapid detection card 3 that can rest on Immediately below probe 2.Processor judges that the image that probe 2 uploads does not meet several images for reacting and completing by image recognition Form (non-plug-in card in unreacted completion or the slot), side abandons the image of the upload, if meeting, is analyzed according to image As a result, and saving.
Rotation power supply mechanism should drive rotating disk 1 to rotate, and power supply is electrically directed to the circuit rotated with rotating disk 1 again On pressing plate 4, therefore circuit pressing plate 4 can not connect power supply using conducting wire (can wind when rotation), if being turned with contact Hard link Dynamic friction will lead to contact pad wear, be easy poor contact.In the present embodiment, rotation power supply mechanism includes: bearing block 5, support Column 6, motor 7, ring gear 8, the first pot magnetic core 9 and the second pot magnetic core 10.Ring gear 8 and 5 inner bearing of bearing block connect It connects, support column 6 is perpendicularly fixed at 5 bottom of bearing block, is coaxially disposed with ring gear 8 and rotating disk 1.Motor 7 connects the place Device is managed, (motor shaft ends are equipped with mutually ratcheting with ring gear 8 for driving ring gear 8 rotation under the control of a processor Gear), rotating disk 1 is fixed on ring gear 8, and the first pot magnetic core 9 is fixed in rotating disk 1, and connects circuit pressing plate 4, Second pot magnetic core 10 is fixed on support column 6, and connects power supply, and the first pot magnetic core 9 and the second pot magnetic core 10 are set relatively It sets, and is spaced a predetermined distance.Second pot magnetic core 10 connects power supply, and the first pot magnetic core 9 is rotated relative to the second pot magnetic core 10, To generate electric current on the first pot magnetic core 9, and electric current is transferred to circuit pressing plate 4, the rotation power supply mechanism of the present embodiment Do not need conducting wire also not contact firmly.Specifically, the first pot magnetic core 9 and the second pot magnetic core 10 can pass through one group of clamping plate respectively It is installed, clamping plate includes: that lower installation board 11 and two pieces of upper mounting plates 12 are constituted, naturally it is also possible to be other mounting structures.
Rotation power supply mechanism includes: protective cover 13, and protective cover 13 connects rotating disk 1, and covers the first pot magnetic core 9 and the Two pot magnetic cores 10 play a protective role to two pot magnetic cores.
In the present embodiment, probe 2, which is also used to scan while obtaining observation window image under the control of a processor, exempts from Identification code in epidemic disease rapid detection card 3 reads patient information, and is uploaded to processor, and processor is used in immune quickly detection Card is bound and is saved after the reaction was completed, by patient information and analysis result, i.e., automatically ties up patient information and analysis result It is fixed, it does not need manually to be handled.If unreacted is completed, the image of patient information and upload is abandoned.
Due to being not that each slot is inserted with immune rapid detection card 3, the especially more situation of blank slot at any time Under, the processor most of the time is not to cause processor resource to waste in the image of identification observation window.Therefore the present embodiment In, sensor is equipped in each slot, sensor connects circuit pressing plate 4 (i.e. circuit pressing plate 4 is sensor power supply), for that will insert The signal that immune rapid detection card whether is inserted into slot is sent to processor, and processor is calculating the slot to non-plug-in card through overscan When retouching first 2, the slot of control rotation power supply mechanism driving rotating disk 1 directly rotation to next plug-in card rests on probe 2 Scanning area.Specifically, in the processor, settable 2 position of probe is 0 °, and before booting rotation, probe 2 is arranged Sensor in the slot of lower section is 0 °, while the corresponding angle of other sensors is successively initialized by rotation direction, then is turning When dynamic, the angle of each sensor relative scanning head 2 can be calculated in real time according to the number of rotation, to judge inserting for blank Whether slot will be scanned first 2.
Quick analytic instrument is immunized in the electric field action film of the present embodiment further include: detection card recovering mechanism, detection card recycling Mechanism includes: recycling box 15, slide unit bracket 16, straight line slide unit 17, detection card pushing hands 18, and straight line slide unit 17 is fixed on slide unit bracket On 16, and connecting detection card pushing hands 18 and processor, recycling box 15 are located at 16 side of slide unit bracket, and slot bottom is equipped with for making The channel 19 that detection card pushing hands 18 passes through.When work, detection card pushing hands 18 is located at 1 lower section of rotating disk close to 6 side of support column, place Reason device judges the immune reacted completion of rapid detection card 3 after carrying out image analysis, and side controls straight line slide unit 17 and drives detection Card pushing hands 18 is displaced outwardly, so that rapid detection card 3, which is immunized, in this releases slot, is fallen into recycling box 15.
Detection card recovering mechanism is located at 2 lower section of probe, convenient for rapid detection card 3 directly is immunized in this after completion of the reaction Slot is released, does not need to reposition.
It further includes casing 20 that quick analytic instrument, which is immunized, in the electric field action film of the present embodiment, and casing 20 is equipped with for making slot The opening 21 of exposing, it is preferable that be equipped with transparent overhead door at opening 21, close overhead door when not operating.
Human-computer interaction module 22 is additionally provided on the casing 20, human-computer interaction module 22 connects processor, human-computer interaction module 22 instruct for inputting relevant configuration information for processor or inputting relevant operation, or provide output interface for processor.People Machine interactive module 22 can be the composite structure of keyboard and display, be also possible to touch screen, for showing patient information and dividing Analysis is as a result, or input relevant configuration information and input relevant operation instruction by operation interface.It is immune quick in electric field action film The analyzer course of work, and need to be inserted into an immune rapid detection card 3 is worked as by the disk 1 that stops rotating of human-computer interaction module 22 Preceding stepping rotation status makes processor calculate and (initialize opposite 0 ° of the angle coordinates of opening 21) one and currently leaves mouth A 21 nearest blank slots, and blank slot is rotated at opening 21.
In the present embodiment, processor and power supply can be located at any feasible position in casing 20.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (10)

1. quick analytic instrument is immunized in a kind of electric field action film characterized by comprising supporting plate, probe, processor and power supply, The supporting plate is equipped with the slot for being inserted into immune rapid detection card, and the immune rapid detection card is equipped with for reacting The circuit structure of electric field is formed on film, and the positive electrode contact for circuit structure power-up and negative electrode touching are equipped in the slot Point, the probe is located at the slot-side, for obtaining the observation window of immune rapid detection card under the control of a processor Image, and the observation window image is sent to the processor, the processor is based on image recognition and obtains analysis as a result, institute Stating power supply is that probe, positive electrode contact and negative electrode contact and processor are powered.
2. quick analytic instrument is immunized in electric field action film as described in claim 1, which is characterized in that further include: rotation power supply machine Structure, the supporting plate include: rotating disk and circuit pressing plate, and multiple slots are circumferentially uniformly distributed along rotating disk, and the circuit pressing plate is solid Determine on the rotating pan, and is covered on the region above the slot and is equipped with the positive electrode contact and negative electrode contact, it is described It rotates power supply mechanism and connects the power supply, circuit pressing plate and processor, the processor controls the rotation power supply mechanism driving Step-length rotates the rotating disk by a predetermined angle, so that each immune rapid detection card is stopped in the scanning area of the probe It stays, and controls probe and obtain the observation window image.
3. quick analytic instrument is immunized in electric field action film as claimed in claim 2, which is characterized in that the rotation power supply mechanism packet It includes: bearing block, support column, motor, ring gear, the first pot magnetic core and the second pot magnetic core, the ring gear and bearing Seat inner bearing connection, the support column are perpendicularly fixed at bearing block bottom, are coaxially disposed with ring gear and rotating disk;Motor connects The processor is connect, for driving the ring gear to rotate under the control of a processor, the rotating disk is fixed on the ring On shape gear, the first pot magnetic core is fixed in the rotating disk, and connects the circuit pressing plate, the second pot magnetic Core is fixed on the support column, and connects the power supply, and the first pot magnetic core and the second pot magnetic core are oppositely arranged, and is spaced Preset distance.
4. quick analytic instrument is immunized in electric field action film as claimed in claim 3, which is characterized in that the rotation power supply mechanism packet Include: protective cover, protective cover connects the rotating disk, and covers the first pot magnetic core and the second pot magnetic core.
5. quick analytic instrument is immunized in electric field action film as claimed in claim 2, which is characterized in that the probe is also used to The identification code in immune rapid detection card is scanned under the control of processor while obtaining observation window image, reads patient's letter Breath, and is uploaded to the processor, the processor be used for immune rapid detection card after the reaction was completed, by patient information and divide Analysis result is bound and is saved.
6. quick analytic instrument is immunized in electric field action film as claimed in claim 2, which is characterized in that be equipped in each slot Sensor, the sensor connect the circuit pressing plate, for sending out the signal for whether being inserted into immune rapid detection card in slot It send to the processor, the processor is when the slot calculated to non-plug-in card is scanned, control rotation power supply mechanism drive It moves the rotating disk and directly rotates to the slot of next plug-in card the scanning area for resting on the probe.
7. quick analytic instrument is immunized in electric field action film as claimed in claim 2, which is characterized in that further include: detection card recycling Mechanism, the detection card recovering mechanism include: recycling box, slide unit bracket, straight line slide unit, detection card pushing hands, and straight line slide unit is fixed On slide unit bracket, and the connection detection card pushing hands and processor, recycling box are located at slide unit bracket side, the slot bottom Equipped with the channel for passing through detection card pushing hands.
8. quick analytic instrument is immunized in electric field action film as claimed in claim 7, which is characterized in that the detection card recovering mechanism Below the probe.
9. quick analytic instrument is immunized in electric field action film as described in claim 1, which is characterized in that further include: casing, the machine Shell is equipped with the opening for exposing slot.
10. quick analytic instrument is immunized in electric field action film as claimed in claim 9, which is characterized in that be additionally provided on the casing Human-computer interaction module, the human-computer interaction module connect the processor.
CN201910788846.9A 2019-08-26 2019-08-26 Quick analytic instrument is immunized in electric field action film Pending CN110456045A (en)

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CN201910788846.9A CN110456045A (en) 2019-08-26 2019-08-26 Quick analytic instrument is immunized in electric field action film

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CN201910788846.9A CN110456045A (en) 2019-08-26 2019-08-26 Quick analytic instrument is immunized in electric field action film

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Application publication date: 20191115