CN110447799A

CN110447799A - A kind of complex solid plant beverage and preparation method thereof for improving intestinal flora

Info

Publication number: CN110447799A
Application number: CN201810432982.XA
Authority: CN
Inventors: 程志雄
Original assignee: Beijing Double Philippines Reed Health Technology Co Ltd
Current assignee: Beijing Double Philippines Reed Health Technology Co Ltd
Priority date: 2018-05-08
Filing date: 2018-05-08
Publication date: 2019-11-15

Abstract

The present invention discloses a kind of compound solid beverage and preparation method thereof for improving intestinal flora, and compound solid beverage includes 200-800 parts of oligofructose, lactic acid bacteria compounding powder 100-500 parts, 80-520 parts of maltitol, 80-520 parts of xylitol, 66-264 parts of taro powder, 40-160 parts of raspberry powder, 40-160 parts of blackcurrant powder, 40-160 parts of strawberry powder, 4-16 parts of synthetism rasp berry fruit powder, 8-32 parts of A Sayi fruit powder, 12-48 parts of Noni fruit powder, 8-32 parts of Cranberry powder, 8-32 parts of blueberry powder.Preparation method is to mix each component to obtain the final product, and compound solid beverage provided by the invention can not only improve the breeding of beneficial bacterium in enteron aisle, and long-term consumption will not influence other normal floras.

Description

A kind of complex solid plant beverage and preparation method thereof for improving intestinal flora

Technical field

The present invention relates to technical field of health care more particularly to a kind of for improving the complex solid plant of intestinal flora Beverage and preparation method thereof.

Background technique

Probiotics, which refers to, plays beneficial effect by improving the host intestine flora ecological balance after use, reaches and improves place The active bacteria formulation and its metabolite of main (humans and animals) general level of the health and health status.Idicatio includes: neutral or acute abdomen It rushes down, indigestion, abdominal distension and intestinal bacilli illness etc..In actual clinical application, probiotics is also comprehensive frequently as intestines easily swash The adjuvant treatment of simulator sickness and inflammatory bowel disease.

From the point of view of current medical evidence, it is comprehensive to improve intestines easily swash for the remission rate of raising irritable bowel syndrome for probiotics The quality of life curative effect for patients with inflammatory bowel disease of seeking peace is clear, but the drug or functionality for improving enterobacteriaceae realm is used for a long time The ability that food can make enteron aisle gradually lose self-reproduction beneficial bacterium, human body intestinal canal regulatory function can obviously weaken over time, And then human health is damaged, or body is caused to generate adverse reaction, bacillary and fungoid septicopyemia such as occurs, promotes to have Evil metabolic activity, overstimulation is immune, gastrointestinal reaction and gene transfer etc..

Such as: the Chinese invention patent of Publication No. CN201010292562.X discloses a kind of improvement human body intestinal canal flora The drug and preparation method of balance, drug include following component: with 4-10 parts of dried orange peel, frying Semen Lablab Album 10-30 parts, Fu Ling 10-30 Part, 5-20 parts of wrinkled giant hyssop, 7-25 parts of lotus leaf, the extract that 7-25 parts of dandelion are raw material；And 200-400 parts of oligofructose； The above are components by weight percent proportion, shiftings etc..The drug for human body intestinal canal flora balance that the invention provided improve with the energy of ultrasonic wave, It dissolves out the effective component of vegetable drug in solution, is aided with oligofructose made from modern science as prebiotics, removes people The damp and hot virulence factor of body, to achieve the purpose that Fast-Balance human body intestinal canal flora；And Publication No. The Chinese invention patent of CN201210336538.0 disclose a kind of levulan extract preparation improve intestinal flora drug, Application in food or health care product, the molecular weight ranges of the levulan extract are made with the following method 2000~10000 : Zhejiang is produced into Radix Ophiopogonis (Zhejiang Radix Ophiopogonis) root tuber first and extracts removal of impurities through ethyl alcohol, is then extracted with water, after ethanol precipitation, A kind of levulan extract of drying to obtain (in 2000~10000 range of molecular weight).It is examined using Central obesity mouse model Examine the function of the levulan extract, it was demonstrated that the levulan extract has the effect for being significantly improved intestinal flora.

Above-mentioned patent individually discloses the Chinese medicine and Western medicine for improving intestinal flora, and all has certain drug effect, but It is the non-natural green food of the two, there are long term usages easily to have an impact to normal flora in enteron aisle, reduces intestinal regulatory function And the problem that medication crowd is limited.

Summary of the invention

It is an object of the invention to overcome defect described in the prior art, to provide a kind of pure natural for improving Compound solid beverage of intestinal flora and preparation method thereof.The compound solid beverage can not only improve the numerous of beneficial bacterium in enteron aisle It grows, and long-term consumption will not influence other normal floras.

To achieve the goals above, the present invention provides the following technical solutions as follows:

It is a kind of for improving the compound solid beverage of intestinal flora, the raw material including following parts by weight:

200-800 parts of oligofructose, lactic acid bacteria compound powder 100-500 parts, 80-520 parts of maltitol, xylitol 80-520 Part, 66-264 parts of taro powder, 40-160 parts of raspberry powder, 40-160 parts of blackcurrant powder, 40-160 parts of strawberry powder, synthetism rasp berry fruit powder 4-16 parts, 8-32 parts of A Sayi fruit powder, 12-48 parts of Noni fruit powder, 8-32 parts of Cranberry powder, 8-32 parts of blueberry powder.

Preferably: above-mentioned for improving the compound solid beverage of intestinal flora, the raw material including following parts by weight: oligomeric fruit 240-640 parts sugared, lactic acid bacteria compounds powder 120-400 parts, 96-416 parts of maltitol, 96-416 parts of xylitol, taro powder 79.2- 211.2 parts, 48-128 parts of raspberry powder, 48-128 parts of blackcurrant powder, 48-128 parts of strawberry powder, synthetism rasp berry fruit powder 4.8-12.8 Part, 9.6-25.6 parts of A Sayi fruit powder, 14.4-38.4 parts of Noni fruit powder, 9.6-25.6 parts of Cranberry powder, blueberry powder 9.6-25.6 Part.

Preferably: above-mentioned for improving the compound solid beverage of intestinal flora, the raw material including following parts by weight: oligomeric fruit Sugar 500 parts, lactic acid bacteria compounding 300 parts of powder, 300 parts of maltitol, 300 parts of xylitol, 330 parts of taro powder, 100 parts of raspberry powder, 100 parts of blackcurrant powder, 100 parts of strawberry powder, 10 parts of synthetism rasp berry fruit powder, 20 parts of A Sayi fruit powder, 30 parts of Noni fruit powder, Cranberry 20 parts of powder, 20 parts of blueberry powder.

Preferably: it is above-mentioned for improving the compound solid beverage of intestinal flora, it further include the mixing certain kind of berries perfume of 1-8 parts by weight Essence.

Further: the lactic acid bacteria compounding powder includes lactic acid Bifidobacterium Bi-07,4- of 2.664-3.996wt% The bifidobacterium lactis HM019's and 86.008-90.672wt% of lactobacillus acidophilus NCFM, 2.664-3.996wt% of 6wt% Oligofructose.

Further: the lactic acid bacteria compounding powder includes the thermophilic of lactic acid Bifidobacterium Bi-07,5wt% of 3.33wt% The oligofructose of the bifidobacterium lactis HM019 and 88.34wt% of Lactobacillus lactis NCFM, 3.33wt%.

Preferably: the taro powder the preparation method comprises the following steps:

A. cutting is the glycan grain of 9-12mm after fresh glycan being removed the peel；

B. the glycan grain is air-dried into dehydration to water content and is not more than 40wt%, it is dry to obtain glycan；

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 80-100 DEG C, it is described ripe The pressure of change is 101.3-202.6KP, by the dry air-cooled dehydration of progress of glycan after curing, until water content is not more than 15wt%, It is dry that glycan must be dehydrated；

D. the dehydration glycan dry powder is broken to fineness no more than 246um to get taro powder.

Preferably: the raspberry powder the preparation method comprises the following steps:

S1: it is sliced after fresh raspberry cleaning is drained, microwave drying is then carried out at 65-70 DEG C, wherein when dry Between be 10-13min, it is dry to obtain raspberry；

S2: the raspberry is done to the quick-frozen 2-2.5min of liquid nitrogen spraying of -180--160 DEG C of use, is then lyophilized, is obtained again It is dry to freeze raspberry；

S3: the freezing raspberry dry powder is broken to fineness no more than 246um to get raspberry powder；

Wherein, the blackcurrant powder, strawberry powder, synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, Cranberry powder with And the preparation method of blueberry powder is identical as the preparation method of the raspberry powder.

Further: the vacuum degree of freeze-drying described in step S2 is 0.1-0.5KPa, and condenser temperature is -30 DEG C, heating temperature Degree is 35-40 DEG C, heating time 2-3h.

A method of the compound solid beverage for improving intestinal flora is prepared, is included the following steps:

(1) the synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, Cranberry powder and blueberry powder are mixed into 25- 35min obtains the first mixed powder；

(2) first mixed powder is compounded into powder, maltose with the raspberry powder, blackcurrant powder, strawberry powder, lactic acid bacteria Alcohol, xylitol, taro powder and oligofructose mixing 1.8-2.2h are to get the compound solid beverage.

Oligofructose is also known as fructooligosaccharide, refers to that 2-5 fructosyl is chain link, using a glucosyl group as the end of chain Base, skeleton links the carbohydrate to be formed based on fructosyl → fructose connecting key.Refer to 1-4 fructosyl with β -2, The ketose that 1 key connection is formed on the D-Fructose base of sucrose

(GF2), the mixture of six sugar (GF5) of Nystose (GF3), sugarcane sugar (GF4) and sugarcane fruit.Oligofructose is one Kind natural active matter, sugariness are 0.3-0.6 times of sucrose, have not only maintained the pure sweetening characteristics of sucrose, but also than sucrose sweet taste Clearly, it is to have to adjust intestinal flora, is proliferated Bifidobacterium, promotes the absorption of calcium, adjust blood lipid, immunological regulation, anti-caries tooth etc. The novel sweetener of healthcare function, after human body takes in oligofructose, oligofructose by Bifidobacterium absorption, (seldom can by oligofructose By in alimentary canal gastric acid and enzyme decompose, it is extremely difficult to be absorbed by the body), Bifidobacterium is proliferated rapidly, internal profitable strain bifid bar Bacterium number amount can inhibit external source pathogenic bacteria and the intrinsic putrefactivebacteria of enteral such as salmonella, Escherichia coli and clostruidium etc. is rotten The growth and breeding of bacterium is lost, reduces the generation and accumulation of enteral toxic metabolites (such as indoles, nitroso ammonia), while rapidly by toxicity Metabolin excretes, promote intestines peristalsis, mitigate burden of liver, prevent constipation and diarrhea, play the role of it is liver-protective, in advance The effects of preventing various chronic diseases, cancer is obvious.

Lactic acid bacteria (lactic acid bacteria, LAB) is that one kind can be generated largely using fermentable carbohydrate The common name of the bacterium of lactic acid, refer to fermenting carbohydrate primary product be lactic acid it is a kind of without gemma, gram-positive bacterium it is total Claim, be prokaryotes, all bacteriums that can generate lactic acid from the fermentation process of glucose or lactose are referred to as lactic acid bacteria, this is The quite numerous and jumbled bacterium of a group can at least be divided into 18 categories at present, share more than 200 kinds, and common lactic acid bacteria, vigor is extremely weak, it Can only survive in relatively limited environment, once being detached from these environment, its own can also be destroyed.Only pass through special work The lactic acid bacteria of skill processing gets to enteron aisle, into the lactic acid bacteria of enteral, it is necessary to it is more, energetic to have quantity, competence exertion its Biological effect.Lactic acid bacteria can promote growth of animal, adjust composition of gut flora, maintain microecological balance, to improving stomach and intestine Road function；Improve food digestion rate and biological value；Serum cholesterol is reduced, endotoxin is controlled；Inhibit spoilage organisms in enteron aisle raw It is long, improve immunity of organisms etc..

All parasitism has a large amount of microorganisms to the entire alimentary canal of animal under normal circumstances.For its effect, three can be divided into Class: 1. symbiosis type, mainly facultative anaerobic bacteria, in the ecological balance, their synthesis of vitamin and protein, digestion is inhaled Receive, biological antagonist and the functions such as immune it is advantageous to host.2. pathogenic type, quantity is few under normal circumstances, parasitizes normal portion Position, is unlikely to that host is made to fall ill.If out of control, the adverse reaction of host will lead to.3. intermediateness type has physiology simultaneously With two kinds of effects of causing a disease.The balance of micropopulation, it is particularly significant to the health of body, and lactic acid bacteria can adjust this micro- life State balance, ensures host's normal physiological condition.Lactic acid bacteria is enteron aisle often in bacterium, after livestock and poultry take lactic acid bacteria, thus it is possible to vary enteron aisle Interior environment inhibits harmful bacteria breeding, adjustment gastrointestinal bacterial flora balance.Lactic acid bacteria is closely tied by adhesin with protection of intestinal mucosal barrier cells It closes, is colonized occupy-place on intestinal mucosa surface, becomes the chief component of physiologic barrier, to reach recovery host resistance, repair Multiple intestinal flora barrier, the effect for curing intestines problem.If this barrier is by the destruction of antibiotic or other factors, host The position that can make the enteral bacterium abnormality proliferation with drug resistance to foreign bacteria resistance and replace dominant bacteria is lost, intestines are caused The imbalance of microecological balance in road.

Maltitol is a kind of novel functional sweetener also known as hydrogenated maltose, and chemical name is the Portugal 4-O- α-D- Grape glycosyl-D- glucitol, molecular formula C₁₂H₂₄O₁₁, relative molecular mass 344.31.Maltitol is white crystalline powder Or colorless and transparent neutral thick liquid, it is soluble easily in water, do not dissolve in methanol and ethyl alcohol.The sugariness of maltitol is sucrose 85%-95% has the characteristics that heat resistance, acid resistance, moisture retention and non-fermented, does not play Maillard reaction substantially.Malt Sugar alcohol cannot almost decompose in human body for saliva, gastric juice, small goldbeater's skin enzyme etc., and calorific value is only the 5% of sucrose, take in human body In interior maltitol, about 10% is used as using energy source after small intestine is decomposed and absorbed；Remaining 90% big enteral bacterium make Short chain fatty acids are decomposed under, a part is utilized by intestinal bacterium, but is not easy to be utilized by mould, yeast and lactic acid bacteria, can be prevented Saprodontia, remaining can not digest and excrete.

Xylitol is also known as pentitol, molecular formula C₅H₁₂O₅, be a kind of five-state controller, xylitol be from silver birch, Oak Tree, A kind of natural sweetener extracted in the plant materials such as corncob, bagasse is widely present in various water fruits and vegetables, paddy Among class, commodity xylitol is carried out the agricultural crops such as corncob, bagasse prepared by deep processing, is a kind of natural, strong The sweetener of health, xylitol sugariness is suitable with sucrose, is dissolved in absorbable amount of heat when water, is absorbed heat in all sugar alcohol sweeteners It is worth maximum one kind, xylitol cannot be produced cariogenic bacterial fermentation and be utilized in oral cavity, can inhibit streptococcus growth and acid It generates, it is not cariogenic and play the role of anti-caries.Xylitol is the intermediate of human body carbohydate metabolism, lacks insulin influence in vivo In the case of glycometabolism, promote without insulin, xylitol can also penetrate cell membrane, be absorbed by tissue utilization, and liver glycogen is promoted to close At, for cell with nutrition and energy, and blood glucose value will not be caused to increase, eliminate more than three symptoms after diabetes patient takes (more foods, More drinks, diuresis), it is the sugar substitutes for being most suitable for the trophism of patients with diabetes mellitus.

Glycan alias perfume (or spice) ginseng, chestnut, native goldenrain tree, taro powder extract effective nutritional ingredient in glycan, remain original The nutritive value of glycan, and be allowed to more easily store, save because having sloughed extra moisture, concentration is higher.On the market now Existing taro powder it is general have two classes: the first kind is " pure taro powder " (such to can be collectively referred to as original powder), that is, directlys adopt glycan Powder is that raw material does not add pure natural 100% product of any additive in addition to carrier.Second class is on the basis of a kind of taro powder It is upper to add such as: white sugar, the product of edible essence；Product content such in this way lowers significantly, so advantage of lower cost, price It can be cheaper.The taro powder use herein arrived is the original powder described in the first, and glycan is starch-containing 78.55%, protein 7.26%, polysaccharide 5%, also containing crude fibre, carrotene, thiamine, ash content, calcium, phosphorus, iron, selenium, riboflavin, niacin, anti-bad Hematic acid etc., food have scattered plot qi-regulating, removing toxic substances tonifying spleen, reducing fever relieving cough drug effect.Glycan in glycan can enhance the immunization machine of human body System, increases the resistance to disease, and long-term consumption can detoxify, nourish the body.Taro powder can restore enteron aisle PH numerical value, enteron aisle PH After value restores normal, the flora in enteron aisle is more healthy, reduces the generation of cancer in enteron aisle.

Raspberry scientific name is Rubus corchorifolius (Rubus corchorifolius L.f.) also known as mountain throws son, milk bubble, spreads seedling bubble, three Month bubble, April bubble, dragon-boat bubble, barley bubble, bubble youngster thorn, pierce cucurbit, steamed bun spinach, high foot wave, have the supporing yang improving eyesight of arresting seminal emission kidney-nourishing, wake up The effect of wine quenches the thirst, resolving sputum is detoxified, cure mainly the diseases such as kidney deficiency, spermatorrhea, drunk, erysipelas.Leaf slight bitter, removing toxic substances, detumescence, sore etc., The diseases such as abscess of throat, multiple abscess, mazoitis.Raspberry powder extracts effective nutritional ingredient in raspberry, remains original raspberry Nutritive value, studies have shown that the flavonoids extracted from RubusidaeusL. and RubuschamaemorusL. plant, five Flavonol, 4,5,7- trihydroxyflavones all have significant antibacterial action, and Tan Mingxiong etc. reports Parvifolius to large intestine Bacillus, Pasteurella have apparent bacteriostatic activity, and minimal inhibitory concentration (MIC) can be complete in the case of 10g/mL, 10g/mL Inhibit the breeding of bacillus, bacteriostatic activity is better than control drug streptomysin and sulfa drugs.

Blackcurrant scientific name blackcurrant (Ribes nigrum L.), also known as non-irrigated grape, semen sojae atricolor, black fruit tea Fischer, craze for Japanese pop culture one are breathed out It reaches, currant, elements of black currant, blackcurrant fruit is rich in multivitamin, carbohydrate and organic acid etc., especially Vitamin C content It is higher, considerable sylvite and magnesium salts are contained in blackcurrant fruit, the major function of sylvite is to reinforce the excitability of muscle, is stablized It is not normal to change rule for heart muscle cell membrane；Containing the bioflavonoid of higher amount in blackcurrant fruit, artery sclerosis journey can be effectively reduced Degree, keeps the angiomalasia to become fragile thinning, improves the permeability of blood vessel, can prevention of arterial it is athero- hard, as the substance of anti-aging, Nucleus formation with blocking nitrosamine formation has antioxidation, and Ascorbic Acid also has synergistic effect.With the prevention and treatment heart The effect of cranial vascular disease and there is anticancer activity, while having very strong cancer-preventing health effectiveness.

Strawberry also known as the foreign certain kind of berries, the certain kind of berries, fruit, the red certain kind of berries, Strawberry, strawberry nutrition value is abundant, is known as being " fruit emperor Afterwards ", vitamin C rich in, VitAVitE, nicotinic acid, vitamin B1, vitamin B2, carrotene, tan The nutriments such as acid, aspartic acid, copper, strawberry amine, pectin, cellulose, folic acid, iron, calcium, ellagic acid and anthocyanidin.Especially Contained vitamin C, content are all 7-10 times higher than apple, grape.And contained malic acid, citric acid, vitamin B1, dimension life Plain B2 and carrotene, calcium, phosphorus, the content of iron are also 3-4 times higher than apple, pears, grape.It is fine rich in diet abundant in strawberry Dimension can promote the wriggling of gastrointestinal tract, promote the food digestion in gastrointestinal tract, improve constipation, prevent the generation of acne, intestinal cancer.

Synthetism rasp berry are the fruit of elder (scientific name: Sambucus williamsii Hance), elder also known as justice Always, pubescent angelica root, horse urine disturb, intermediate torricellia root and leaf, most important ingredient is polyphenol compound in synthetism rasp berry, including anthocyan and Flavonoids.Synthetism rasp berry also contain vitamin, minerals, amino acid and sterols, and identifiable substance includes vitamin A, dimension Raw element C, iron, play antioxidant also rich in, and resistance to oxidation is 20 times of Vit C, and 50 times of Vit E, except this has Synthetism rasp berry also have effects that antiviral and improve immunity except nutritional ingredient.

Ah's Say, also known as not old fruit, the best soldier of free radical, life fruit, A Sayi berry, compatriots are referred to as the Brazilian certain kind of berries, Natural nutrient component and antioxidant content rich in, including Omega3 fatty acid (required fatty acid, to health ten It is point important, but human body voluntarily can not be manufactured effectively), amino acid, minerals, needs crucial vitamin and fiber.Brazil The certain kind of berries can help the vigor of renewing one's youth, cleaning toxin expelling, wound healing, purify the blood, improves anaemia, diarrhea, fever, bleeding, jaundice, liver Disease, helminth and ulcer.

Noni fruit (Noni) is the fruit of beach wood Morinda offcinalis How.Its fruit has the composition rich in human body cell body cell, has The effect of salubrity.Noni extract is safe natural, has antioxidant activity and protection myocardial cells effect, Adjustable damaged myocardium cellular energy metabolism, delays heart failure process.

Cranberry is also known as cranberry, mossberry, cranberry, european cranberry, climing more plum, the crane certain kind of berries, and Cranberry contains special chemical combination Object-condensed tannins, Cranberry help to inhibit a variety of pathogenic bacterias to grow and breeding, prevent these pathogenic bacteria and thin in vivo Born of the same parents' (such as urothelial cell) are sticked, and are prevented and are controlled women's urethral infection and inhibit to lead to gastric ulcer even stomach The infection of the helicobacter pylori of carcinogenesis；It assists in keeping the integrality of the bladder wall simultaneously and maintains the normal pH value of urethra.

Blueberry English name: Blueberry, alias indigo plant plum, bog bilberry, sincere persimmon, beep thermophilic, bilberry, pasture fruit, great bilberry are blue In certain kind of berries fruit other than conventional sugar, acid and Vc, it is rich in VE, VA, VB, SOD, arbutin, protein, anthocyanin, dietary fibre And the mineral elements such as K, Fe, Zn, Ca abundant.According to small berries research institute, Jilin Agriculture University to 14 indigo plants of overseas introduction Certain kind of berries variety analysis, anthocyanin pigments content is up to 163mg/100g, fresh fruit VE content 9.3L in fruit | and g/100g fresh fruit is it Even tens times of several times of his fruit such as apple, grape.Total amino acid content 0.254%, hawthorn more abundant than amino acid content It is also high.Nutritional ingredient rich in Blueberry, having prevents cranial nerve aging, protection eyesight, heart tonifying, anticancer, softening Blood vessel such as enhances the immune of the body at the functions, and nutritional ingredient is high, and water-soluble dietary fiber can promote intestines peristalsis in blueberry, prevents It treats constipation, fruit has convergence, heat-clearing and other effects, and being used as medicine can stomach strengthening and digestion promoting, only diarrhea.

Essence is by the concentration aromatic oil of artificial synthesized imitation fruit and natural perfume material smell, it is a kind of artificial musk Material, primary raw material are essential oil, medicinal extract, absolute oil, balm, botany bar gum, oleoresin, and essence is at least by several spice materials or even several Ten kinds of natural and synthetic perfume composition or organic compound complexs.Used herein arrive is mixing certain kind of berries essence, used Raw material is natural perfume material.The allotment of essence can be by forming as follows: 1. perfume base-shows the main body of odor type feature；2. blender- By reconcile various composition fragrance for the purpose of ingredient；3. dressing agent-makes the ingredient of essence variation style；4. fixation type-itself It is not volatile, and the volatility of other volatile fragrance can be inhibited, slows down its volatilization；5. diluent-is suitably fragrance Desalinate and dissolution and dilution is made to crystallization fragrance and resin-like face cream, itself answers odorless, stable, safety and price is low.

The invention has the benefit that

(1) compound solid beverage of the invention is used to improve intestinal flora, can improve constipation, promote digestion, builds up health, Pharmacology of the invention are as follows: firstly, taro powder, raspberry powder, blackcurrant powder, strawberry powder, synthetism rasp berry fruit powder in the application prescription, Dietary fiber rich in Ah's Say fruit powder, Noni fruit powder, Cranberry powder and blueberry powder, can promote intestines peristalsis, clearly Intestines toxin expelling improves constipation；Secondly, being rich in various vitamins, especially vitamin C in these above-mentioned fruit powders, it can build up health, subtract Few sick probability；In addition to this, the oligofructose in this prescription can be obviously improved the ratio of microbial population in enteron aisle, increase The quantity of enteral Bifidobacterium reduces and inhibits the generation of enteral corrupt substance and the growth of harmful bacteria, and then adjusts intestines Road inner equilibrium；In addition it also added lactic acid bacteria compounding powder in this prescription, lactic acid bacteria compounds the lactic acid bacteria containing multiple types in powder, respectively Type lactic acid bacteria effectively supplement different users because caused by sick or the age growth lactic acid bacteria losing issue or because Flora unbalance in human body intestinal canal caused by the long-term use of wide spectrum strength antibiotic based on lactic acid bacteria, it is domestic at present Exobiology man it has proven convenient that in human body lactic acid bacterium number actual state, have become and examine the weight whether had good health and a long life of people Want index, lactic acid bacteria increased and can gradually decrease with the age of people, when people to old age or it is sick when, lactic acid bacterium number may decline It 100 to 1000 times, is completely disappeared until the elderly is approaching one's end.Usually, for Healthy People 50 times more than patient, long lived elder is older than common People is 60 times more；And beneficial flora is unbalance, will lead to resistance of human body gradually declines, and disease the more is controlled the more more, and health status is gradually Decline；This prescription lactic acid bacteria compounding powder other than lactic acid bacteria is supplemented and is adjusted, also cooperate with above-mentioned various fruit powders and Oligofructose, maltitol and xylitol adjust gastrointestinal bacterial flora, enhancing intestines peristalsis jointly, improve constipation, significant in efficacy； Each component is natural material in this product, and pure in mouth feel is suitable for all kinds of enteron aisle discomfort people's constitutions, and safety is without side-effects, It can take for a long time；

(2) taro powder manufacturing process of the invention first carries out fresh glycan to air-dry crushing, phase after maturation process again Crush efficiency is high for the preparation method of traditional taro powder, it is high-quality to crush；In addition condition of the present invention in low temperature pressurization Under cured, not only can be to avoid high temperature too early dusting to the destruction of taro meal collastromin, but also can guarantee obtained Finished product retains the fragrance of fresh glycan；

(3) raspberry powder of the invention, blackcurrant powder, strawberry powder, synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, climing More certain kind of berries powder and blueberry powder, preparation method thereof is identical, is all made of microwave drying, liquid nitrogen flash freezer and vacuum freeze drying and be combined with each other, real Processing now is dried and dehydrated to certain kind of berries fruit at a lower temperature, so that the nutrition composition in fruit powder obtained is not destroyed, is improved The nutritive value of fruit powder；

(4) method that compound solid beverage of the invention uses equal increments during the preparation process is mixed, specific to grasp It is as method: the component for taking the amount of a small amount of component and equivalent big, while being placed in mixing machinery and being uniformly mixed, it adds with mixed The component that the amount of conjunction object equivalent is big is uniformly mixed, and so a times amount is increased up until adding the big component of whole amount.The present invention adopts With equal increments method carry out that mixing can make that ratio differs greatly in inventive formulation each ingredient mixes more evenly and save Save incorporation time.

Detailed description of the invention

In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with Other attached drawings are obtained according to these attached drawings.

Fig. 1 is the process flow diagram of the embodiment of the present invention.

Specific embodiment

Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.

It should be noted that in the following embodiments 1 part of generation refer to 1g, wherein oligofructose is had by the bright moral biotechnology in Xi'an Limit company provides；Maltitol is provided by Nanjing Corning Chemical Co., Ltd.；Xylitol is had by Shandong dragon power biotechnology share Limit company provides；Lactic acid Bifidobacterium Bi-07 and bifidobacterium lactis HM019 is by the Xi'an biotech inc Ze Lang (former Tai Yuzhiti factory) provides；Lactobacillus acidophilus NCFM is provided by Danisco (China) Co., Ltd；Certain kind of berries essence is mixed by sweet smell Kindness fragrance (China) Co., Ltd provides；

Embodiment 1

The present invention provides a kind of for improving the compound solid beverage of intestinal flora, the raw material including following parts by weight:

200 parts of oligofructose, 100 parts of powder of lactic acid bacteria compounding, 80 parts of maltitol, 80 parts of xylitol, 66 parts of taro powder, tree 40 parts of certain kind of berries powder, 40 parts of blackcurrant powder, 40 parts of strawberry powder, 4 parts of synthetism rasp berry fruit powder, 8 parts of A Sayi fruit powder, 12 parts of Noni fruit powder, 8 parts of Cranberry powder, 8 parts of blueberry powder；

Wherein, lactic acid bacteria compounding powder includes the lactobacillus acidophilus of lactic acid Bifidobacterium Bi-07,4wt% of 2.664wt% The oligofructose of the bifidobacterium lactis HM019 and 90.672wt% of NCFM, 2.664wt%；

The present invention also provides the methods for preparing the above-mentioned compound solid beverage for being used to improve intestinal flora, including walk as follows It is rapid:

(1) taro powder is prepared

A. cutting is the glycan grain of 9mm after fresh glycan being removed the peel；

B. the glycan grain is air-dried dehydration to water content is 40wt%, and it is dry to obtain glycan；

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 80 DEG C, the curing Pressure is 101.3KP, and it is dry must to be dehydrated glycan until water content is 15wt% for the dry air-cooled dehydration of progress of glycan after curing；

D. the dehydration glycan dry powder is broken to fineness is 246um to get taro powder；

(2) raspberry powder, blackcurrant powder, strawberry powder, synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, Cranberry are prepared Powder and blueberry powder, preparation method is consistent, now by taking raspberry powder as an example, it is specific the preparation method is as follows:

S1: being sliced after fresh raspberry cleaning is drained, microwave drying then carried out at 65 DEG C, wherein drying time be It is dry to obtain raspberry by 10min；

S2: the raspberry is done to the quick-frozen 2min of liquid nitrogen spraying of -180 DEG C of use, is then lyophilized again, raspberry must be freezed It is dry；

S3: it is 246um to get raspberry powder that the freezing raspberry dry powder, which is broken to fineness,；

(3) compound solid beverage for improving intestinal flora is prepared

1. by above-mentioned parts by weight weigh synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, Cranberry powder, blueberry powder and Certain kind of berries essence is mixed, the first time that each raw material carries out 25min is mixed, the first mixed powder is obtained；

2. weighing raspberry powder, blackcurrant powder, strawberry powder, lactic acid bacteria by above-mentioned parts by weight compounds powder, maltitol, xylose Alcohol, taro powder and oligofructose, and mixed with second of above-mentioned first mixed powder progress 1.8h, complex solid can be obtained Beverage.

Embodiment 2

240 parts of oligofructose, lactic acid bacteria compounding 120 parts of powder, 96 parts of maltitol, 96 parts of xylitol, 79.2 parts of taro powder, 48 parts of raspberry powder, 48 parts of blackcurrant powder, 48 parts of strawberry powder, 4.8 parts of synthetism rasp berry fruit powder, 9.6 parts of A Sayi fruit powder, Noni fruit powder 14.4 parts, 9.6 parts of Cranberry powder, 9.6 parts of blueberry powder, 1 part of certain kind of berries essence of mixing.

Wherein, lactic acid bacteria compounding powder includes the lactobacillus acidophilus of lactic acid Bifidobacterium Bi-07,4.5wt% of 2.997wt% The oligofructose of the bifidobacterium lactis HM019 and 89.506wt% of NCFM, 2.997wt%；

As shown in Figure 1, it is above-mentioned for improving the method for the compound solid beverage of intestinal flora the present invention also provides preparing, Include the following steps:

(1) taro powder is prepared

A. cutting is the glycan grain of 10mm after fresh glycan being removed the peel；

B. the glycan grain is air-dried dehydration to water content is 38wt%, and it is dry to obtain glycan；

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 85 DEG C, the curing Pressure is 121.56KP, and the dry air-cooled dehydration of progress of glycan after curing is obtained dehydration glycan until water content is not 14wt% It is dry；

D. the dehydration glycan dry powder is broken to fineness is 149um to get taro powder；

S1: being sliced after fresh raspberry cleaning is drained, microwave drying then carried out at 66 DEG C, wherein drying time be It is dry to obtain raspberry by 11min；

S2: the raspberry is done to the quick-frozen 2.2min of liquid nitrogen spraying of -175 DEG C of use, is then lyophilized again, raspberry must be freezed It is dry；

S3: it is 149um to get raspberry powder that the freezing raspberry dry powder, which is broken to fineness,；

(3) compound solid beverage for improving intestinal flora is prepared

1. by above-mentioned parts by weight weigh synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, Cranberry powder, blueberry powder and Certain kind of berries essence is mixed, the first time that each raw material carries out 28min is mixed, the first mixed powder is obtained；

2. weighing raspberry powder, blackcurrant powder, strawberry powder, lactic acid bacteria by above-mentioned parts by weight compounds powder, maltitol, xylose Alcohol, taro powder and oligofructose, and mixed with second of above-mentioned first mixed powder progress 1.9h, complex solid can be obtained Beverage.

Embodiment 3

500 parts of oligofructose, lactic acid bacteria compound 300 parts of powder, 300 parts of maltitol, 300 parts of xylitol, taro powder 330 Part, 100 parts of raspberry powder, 100 parts of blackcurrant powder, 100 parts of strawberry powder, 10 parts of synthetism rasp berry fruit powder, 20 parts of A Sayi fruit powder, Nuo Li 30 parts of fruit powder, 20 parts of Cranberry powder, 20 parts of blueberry powder, 4.5 parts of certain kind of berries essence of mixing；

Wherein, lactic acid bacteria compounding powder includes the lactobacillus acidophilus of lactic acid Bifidobacterium Bi-07,5wt% of 3.33wt% The oligofructose of the bifidobacterium lactis HM019 and 88.34wt% of NCFM, 3.33wt%；

(1) taro powder is prepared

B. the glycan grain is air-dried dehydration to water content is 36wt%, and it is dry to obtain glycan；

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 90 DEG C, the curing Pressure is 162.08KP, and the dry air-cooled dehydration of progress of glycan after curing is obtained dehydration glycan until water content is not 13wt% It is dry；

D. the dehydration glycan dry powder is broken to fineness is 74um to get taro powder；

S1: being sliced after fresh raspberry cleaning is drained, microwave drying then carried out at 68 DEG C, wherein drying time be It is dry to obtain raspberry by 12min；

S2: the raspberry is done to the quick-frozen 2.3min of liquid nitrogen spraying of -170 DEG C of use, is then lyophilized again, raspberry must be freezed It is dry；

S3: it is 74um to get raspberry powder that the freezing raspberry dry powder, which is broken to fineness,；

(3) compound solid beverage for improving intestinal flora is prepared

Embodiment 4

640 parts of oligofructose, lactic acid bacteria compound 400 parts of powder, 416 parts of maltitol, 416 parts of xylitol, taro powder 211.2 Part, 128 parts of raspberry powder, 128 parts of blackcurrant powder, 128 parts of strawberry powder, 12.8 parts of synthetism rasp berry fruit powder, 25.6 parts of A Sayi fruit powder, 38.4 parts of Noni fruit powder, 25.6 parts of Cranberry powder, 25.6 parts of blueberry powder, 6.4 parts of certain kind of berries essence of mixing；

Wherein, lactic acid bacteria compounding powder includes the lactobacillus acidophilus of lactic acid Bifidobacterium Bi-07,5.5wt% of 3.663wt% The oligofructose of the bifidobacterium lactis HM019 and 87.24wt% of NCFM, 3.663wt%；

(1) taro powder is prepared

A. cutting is the glycan grain of 11mm after fresh glycan being removed the peel；

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 90 DEG C, the curing Pressure is 182.34KP, and it is dry must to be dehydrated glycan until water content is 13wt% for the dry air-cooled dehydration of progress of glycan after curing；

D. the dehydration glycan dry powder is broken to fineness is 44um to get taro powder；

S2: the raspberry is done to the quick-frozen 2.4min of liquid nitrogen spraying of -165 DEG C of use, is then lyophilized again, raspberry must be freezed It is dry；

S3: it is 44um to get raspberry powder that the freezing raspberry dry powder, which is broken to fineness,；

(3) compound solid beverage for improving intestinal flora is prepared

Embodiment 5

800 parts of oligofructose, lactic acid bacteria compound 500 parts of powder, 520 parts of maltitol, 520 parts of xylitol, taro powder 264 Part, 160 parts of raspberry powder, 160 parts of blackcurrant powder, 160 parts of strawberry powder, 16 parts of synthetism rasp berry fruit powder, 32 parts of A Sayi fruit powder, Nuo Li 48 parts of fruit powder, 32 parts of Cranberry powder, 32 parts of blueberry powder, 8 parts of certain kind of berries essence of mixing；

Wherein, lactic acid bacteria compounding powder includes the lactobacillus acidophilus of lactic acid Bifidobacterium Bi-07,6wt% of 3.996wt% The oligofructose of the bifidobacterium lactis HM019 and 90.672wt% of NCFM, 3.996wt%；

(1) taro powder is prepared

A. cutting is the glycan grain of 12mm after fresh glycan being removed the peel；

B. the glycan grain is air-dried dehydration to water content is 35wt%, and it is dry to obtain glycan；

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 100 DEG C, the curing Pressure is 202.6KP, and it is dry must to be dehydrated glycan until water content is 12wt% for the dry air-cooled dehydration of progress of glycan after curing；

D. the dehydration glycan dry powder is broken to fineness is 37um to get taro powder；

S1: being sliced after fresh raspberry cleaning is drained, microwave drying then carried out at 70 DEG C, wherein drying time be It is dry to obtain raspberry by 13min；

S2: the raspberry is done to the quick-frozen 2.5min of liquid nitrogen spraying of -160 DEG C of use, is then lyophilized again, raspberry must be freezed It is dry；

S3: it is 37um to get raspberry powder that the freezing raspberry dry powder, which is broken to fineness,；

(3) compound solid beverage for improving intestinal flora is prepared

The pharmaceutical test of the embodiment of the present application 3 is given below:

Animal experiment

1, materials and methods

1.1 samples: the compound solid beverage for being used to improve intestinal flora obtained by the present embodiment 3.

1.2 animals: healthy adult female BAl BIc/C mice, weight 18-22g, by Huaxi Medical Univ's experimental animal center It provides and (quality certification number: moves Guan Zhi 64 in fact in river).

1.3 culture mediums and condition of culture:

Bifidobacterium: using self-control BBL culture medium, the Anaerobic culturel 48-72h at 37 DEG C；

Wherein the ingredient of BBL culture medium includes peptone 15.0g, yeast powder 2.0g, glucose 20.0g, soluble starch 0.5g, sodium chloride 5.0g, 5% cysteine 10.0mL, tomato leachate 400.0mL, Tween 80 1.0mL, liver extracting solution 80.0mL, agar 20.0g, distilled water 520.0mL；Preparation method is to dissolve by heating above-mentioned composition, is sub-packed in built-in voltage regulator tube In test tube, pH value should be 7.0 ± 0.1 at 25 DEG C after sterilizing；

Bacillus acidi lactici: self-designed L S culture medium, the Anaerobic culturel 48h at 37 DEG C are used；

Wherein LS culture medium includes ammonium nitrate l650mg/L, potassium nitrate 1900mg/L, CaCl₂·2H₂O 440mg/L、 MgSO₄·7H₂O 370mg/L、KH₂PO₄ 170mg/L、Na₂-EDTA 37.3mg/L、FeSO₄·7H₂O 27.8mg/L、H₃BO₃ 6.2mg/L、MnSO₄·4H₂O 22.3mg/L、ZnSO₄·7H₂O 8.6mg/L, potassium iodide 0.83mg/L, Na₂MoO·2H₂O 0.25mg/L、CuSO₄·5H₂O 0.025mg/L、CoCl₂·6H₂O 0.025mg/L, vitamin B_l0.4mg/L, inositol 10.0mg/L, sucrose 30g/L；Preparation method is to dissolve by heating above-mentioned composition, is sub-packed in the test tube of built-in voltage regulator tube, after sterilizing PH value should be 5.6 at 25 DEG C；It should be noted that FeSO₄·7H₂O is formulated as that 5.57g is taken to be first dissolved in 1 liter of distilled water, so The ratio in every liter of culture medium containing 5mg is added in culture medium afterwards；Na₂- EDTA is formulated as that 7.45g is taken to be first dissolved in 1 liter of distilled water In, then the ratio in every liter of culture medium containing 5mg is added in culture medium；

Enterobacteria: it (is provided by Hangzhou microorganism reagent factory) using EMB culture medium, is cultivated for 24 hours at 37 DEG C；

Enterococcus: it using self-control EC culture medium, is cultivated for 24 hours at 37 DEG C；

Wherein EC culture medium includes tryptone or shows peptone 20.0g, lactose 5.0g, No. 3 cholate 1.5g, K₂HPO₄·3H₂O 4.0g, potassium dihydrogen phosphate 1.5g, sodium chloride 5.0g, distilled water 1000mL；Preparation method is to dissolve by heating above-mentioned composition, is dispensed In the test tube of built-in voltage regulator tube, pH value should be 6.9 after sterilizing, this culture medium should not be placed in refrigerator before using, to prevent occurring when detection False positive；

C.perfringens: CD culture medium, the Anaerobic culturel 48h at 37 DEG C are used.

Wherein, CD culture medium is provided by Shanghai Jin Mai Biotechnology Co., Ltd.

1.4 experimental methods:

Animal sample is fed with 3d using basal feed, chooses 48 Healthy female BALB/C mices by random group forming criterion It is divided into control group, low dose group, middle dose group and high dose group, wherein low dose group takes drugs to implement containing 2wt% Compound solid beverage 33ml/kg described in example 3；Middle dose group takes drugs as containing 2wt% complex solid described in embodiment 3 Beverage 66ml/kg；High dose group takes drugs to be used for containing 2wt% compound solid beverage 99ml/kg described in embodiment 3 Each dosage group of experimental animal is successively equivalent to 10,20 and 30 times of Coming-of-Age Day recommended doses of recommendation.

Test group is with the compound solid beverage stomach-filling of above-mentioned dosage, and control group is with distilled water stomach-filling, once a day, continuous to fill Stomach 14d, before stomach-filling and after stomach-filling 14d, aseptic collection stool in mice 0.1-0.4g, sets the drying with bead weighed and goes out respectively It in bacterium small test tube, is re-weighed, calculates the weight of stool in mice, be added 10 times of sterile diluent thin liquid, vibrate 1min, it is sufficiently mixed It is even, then successively carry out 10 times and be serially diluted, suitable dilution is selected, is seeded on each culture medium, is trained as required respectively It supports, carries out analysis in groups by the difference of the logarithm of intestinal microflora each before and after stomach-filling.

2, result

Influence (being shown in Table 1) to four kinds of intestinal microfloras of mouse

Influence (log CFU/g, X ± SD, N=12) of 1 compound solid beverage of table to four kinds of intestinal microfloras of mouse

Note: * is that compared with the control group (P < 0.05), # is compared with the control group (P < 0.01)

3, it analyzes

As shown in Table 1, the complex solid of difference orally administration BALB/C mice low dose group, middle dose group, high dose group Beverage 14d, compared with the control group, enterococcus, enterobacteria quantity there are no significant difference in each dosage group mouse intestinal；Low dose Amount, high dose group Bacillus acidi lactici quantity obviously increase, and have significant difference (P < 0.05), and middle dose group Bacillus acidi lactici quantity increases Significantly, there is highly significant difference (P < 0.01)；Low dosage, middle dose group bifidobacteria obviously increase, and have conspicuousness poor Different (P < 0.05).Illustrate that this compound solid beverage can be such that Bacillus acidi lactici in mouse intestinal, Bifidobacterium number increases, to mouse intestines Road flora has improvement result.

Clinical test:

Human body intestinal canal flora detection test

1, it selects study subject: following physical examination: (1) blood, urine, feces routine inspection and liver function is carried out to tested volunteer It checks；(2) test before test-meal is tested of heart rate, blood pressure, electrocardiogram, B ultrasound (liver, gallbladder, spleen, kidney) indices is primary.Selection 31 All normal tested volunteer tests as study subject and uses own control name (male 15, female 16) physical examination index.

2, test procedure: the compound solid beverage 200ml that the daily drinking quality score of study subject is 2% is continuously drunk 15d.It is sterile respectively that subject mixing stool about 10g is taken to set before test-meal tested material and after giving tested material last time for 24 hours It in the dry sterilization conical beaker with bead of weighing, is re-weighed, calculates the weight of excrement, sterile diluent, dilution is added 10 times, 1min is vibrated, is mixed well, then successively carried out 10 times and be serially diluted, selected suitable dilution, be seeded in each training respectively It supports on base, is cultivated as required.Pairing measurement data analysis is carried out by the logarithm of intestinal microflora, and subject is eaten It is observed and is counted with front and back subjective symptoms.

3, experimental result

3.1, the influence to five kinds of intestinal microfloras of human body (being shown in Table 2).

2 human body intestinal canal flora testing result of table (logC FU/g, X ± SD, N=49)

Group	Enterobacteria	Enterococcus	Clostridium perfringens enterotoxin	Bifidobacterium	Bacillus acidi lactici
						Before drinking	7.62±0.70	6.57±1.09	5.84±1.00	8.81±0.93	5.70±1.14
After drinking	7.32±0.81	6.96±0.92	5.46±1.25*	9.41±0.89*	6.34±1.34*

Note: * is (own control) P < 0.01 compared with drinking before tested material

3.2, tested crowd's subjective symptoms observation

After subject drinks tested material, all subjects have no adverse reaction, and 17 people's constipation situations have improvement, and 8 people have food Phenomenon to be increased, 6 people's readmes exhaust increased.

4, interpretation of result

As shown in Table 2, tested crowd drinks compound solid beverage 15d of the invention, enterobacteria, intestines in tested Intestinal Coccus quantity there are no significant difference；Bifidobacterium, Bacillus acidi lactici quantity increase it is significant, in highly significant difference (P < 0.01)；Clostridium perfringens enterotoxin quantity reduces significantly, there is highly significant difference (P < 0.01).Illustrate that compound solid beverage of the invention can Increase human body intestinal bifidobacteria, Bacillus acidi lactici quantity, clostridium perfringens enterotoxin quantity is reduced, and is had to improve to human body intestinal canal flora and be made With.And by observing tested crowd's subjective symptoms, this product has improvement intestinal flora, improves constipation, constitutional effect.

The foregoing is merely a specific embodiment of the invention, but scope of protection of the present invention is not limited thereto, any In the technical scope disclosed by the present invention, any changes or substitutions that can be easily thought of by those familiar with the art, all answers It is included within the scope of the present invention.Therefore, protection scope of the present invention should be with the scope of protection of the claims It is quasi-.

Claims

1. a kind of for improving the compound solid beverage of intestinal flora, which is characterized in that the raw material including following parts by weight:

200-800 parts of oligofructose, lactic acid bacteria compound powder 100-500 parts, 80-520 parts of maltitol, 80-520 parts of xylitol, 66-264 parts of taro powder, 40-160 parts of raspberry powder, 40-160 parts of blackcurrant powder, 40-160 parts of strawberry powder, synthetism rasp berry fruit powder 4- 16 parts, 8-32 parts of A Sayi fruit powder, 12-48 parts of Noni fruit powder, 8-32 parts of Cranberry powder, 8-32 parts of blueberry powder.

2. compound solid beverage according to claim 1, which is characterized in that the raw material including following parts by weight:

240-640 parts of oligofructose, lactic acid bacteria compound powder 120-400 parts, 96-416 parts of maltitol, 96-416 parts of xylitol, 79.2-211.2 parts of taro powder, 48-128 parts of raspberry powder, 48-128 parts of blackcurrant powder, 48-128 parts of strawberry powder, synthetism rasp berry fruit 4.8-12.8 parts of powder, 9.6-25.6 parts of A Sayi fruit powder, 14.4-38.4 parts of Noni fruit powder, 9.6-25.6 parts of Cranberry powder, blueberry 9.6-25.6 parts of powder.

3. compound solid beverage according to claim 1, which is characterized in that the raw material including following parts by weight:

500 parts of oligofructose, 300 parts of powder of lactic acid bacteria compounding, 300 parts of maltitol, 300 parts of xylitol, 330 parts of taro powder, tree 100 parts of certain kind of berries powder, 100 parts of blackcurrant powder, 100 parts of strawberry powder, 10 parts of synthetism rasp berry fruit powder, 20 parts of A Sayi fruit powder, Noni fruit powder 30 parts, 20 parts of Cranberry powder, 20 parts of blueberry powder.

4. compound solid beverage according to claim 1, which is characterized in that further include the mixing certain kind of berries essence of 1-8 parts by weight.

5. compound solid beverage described in any one of -4 according to claim 1, which is characterized in that the lactic acid bacteria compounds powder packet Include lactobacillus acidophilus NCFM, 2.664-3.996wt% of lactic acid Bifidobacterium Bi-07,4-6wt% of 2.664-3.996wt% Bifidobacterium lactis HM019 and 86.008-90.672wt% oligofructose.

6. compound solid beverage according to claim 5, which is characterized in that the lactic acid bacteria compounding powder includes 3.33wt% Lactic acid Bifidobacterium Bi-07,5wt% lactobacillus acidophilus NCFM, 3.33wt% bifidobacterium lactis HM019 and The oligofructose of 88.34wt%.

7. compound solid beverage described in any one of -4 according to claim 1, which is characterized in that the preparation side of the taro powder Method are as follows:

C. carry out low temperature pressurizing and ageing for the glycan is dry, wherein the temperature of the curing be at 80-100 DEG C, the curing Pressure is 101.3-202.6KP, and the dry air-cooled dehydration of progress of glycan after curing is obtained de- until water content is not more than 15wt% Water glycan is dry；

8. compound solid beverage described in any one of -4 according to claim 1, which is characterized in that the preparation side of the raspberry powder Method are as follows:

S1: being sliced after fresh raspberry cleaning is drained, microwave drying then carried out at 65-70 DEG C, wherein drying time be It is dry to obtain raspberry by 10-13min；

S2: the raspberry is done to the quick-frozen 2-2.5min of liquid nitrogen spraying of -180--160 DEG C of use, is then lyophilized, must be freezed again Raspberry is dry；

S3: the freezing raspberry dry powder is broken to fineness no more than 246um to get raspberry powder.

9. compound solid beverage according to claim 8, which is characterized in that the vacuum degree of freeze-drying described in step S2 is 0.1-0.5KPa, condenser temperature are -30 DEG C, and heating temperature is 35-40 DEG C, heating time 2-3h.

10. a kind of prepare for improving the method for the compound solid beverage of intestinal flora as described in any one of claim 1-3, Include the following steps:

(1) the synthetism rasp berry fruit powder, A Sayi fruit powder, Noni fruit powder, Cranberry powder and blueberry powder are mixed into 25-35min, Obtain the first mixed powder；

(2) first mixed powder is compounded into powder, maltitol, wood with the raspberry powder, blackcurrant powder, strawberry powder, lactic acid bacteria Sugar alcohol, taro powder and oligofructose mixing 1.8-2.2h are to get the compound solid beverage.