CN110437997A - Microwave rewarming resuscitation instruments for rewarming recovery - Google Patents
Microwave rewarming resuscitation instruments for rewarming recovery Download PDFInfo
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- CN110437997A CN110437997A CN201910833054.9A CN201910833054A CN110437997A CN 110437997 A CN110437997 A CN 110437997A CN 201910833054 A CN201910833054 A CN 201910833054A CN 110437997 A CN110437997 A CN 110437997A
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- 238000011084 recovery Methods 0.000 title claims abstract description 166
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 100
- 230000005540 biological transmission Effects 0.000 claims abstract description 69
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 50
- 239000007788 liquid Substances 0.000 claims abstract description 48
- 238000010438 heat treatment Methods 0.000 claims abstract description 44
- 239000011521 glass Substances 0.000 claims description 35
- 238000001514 detection method Methods 0.000 claims description 9
- 238000013473 artificial intelligence Methods 0.000 claims description 6
- 239000000835 fiber Substances 0.000 claims description 6
- 239000013589 supplement Substances 0.000 claims description 6
- 238000007710 freezing Methods 0.000 claims description 5
- 230000008014 freezing Effects 0.000 claims description 5
- 230000005855 radiation Effects 0.000 claims description 5
- 238000010521 absorption reaction Methods 0.000 claims description 3
- 238000007689 inspection Methods 0.000 claims description 2
- 238000005119 centrifugation Methods 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 230000001502 supplementing effect Effects 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 102
- 238000000034 method Methods 0.000 description 25
- 239000000463 material Substances 0.000 description 15
- 229940058401 polytetrafluoroethylene Drugs 0.000 description 15
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 15
- 239000004810 polytetrafluoroethylene Substances 0.000 description 15
- 230000008569 process Effects 0.000 description 13
- 238000010586 diagram Methods 0.000 description 11
- -1 polytetrafluoroethylene Polymers 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 230000001276 controlling effect Effects 0.000 description 6
- 239000013307 optical fiber Substances 0.000 description 6
- 230000005684 electric field Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 239000002184 metal Substances 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 238000005138 cryopreservation Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000002706 hydrostatic effect Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000008646 thermal stress Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
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Abstract
The present invention relates to a kind of microwave rewarming resuscitation instruments for rewarming recovery, comprising: microwave power transmission irradiation structure, microwave source device, temperature-detecting device, control device and liquid nitrogen supplementary device；Microwave source device is used to send microwave to microwave power transmission irradiation structure；The microwave that microwave power transmission irradiation structure is used to receive is emitted or is radiated with TE101 mode of resonance；Temperature-detecting device is used to detect the temperature by rewarming recovery sample in microwave power transmission irradiation structure, and obtains temperature data；Control device is connect with temperature-detecting device and microwave source device respectively, the power of the temperature data control microwave source device for being sent according to temperature-detecting device；Liquid nitrogen supplementary device is for supplementing liquid nitrogen into microwave power transmission irradiation structure.Realizing makes to be evenly heated by rewarming recovery sample, and control is by the purpose of rewarming recovery sample heating rate.
Description
Technical field
The present invention relates to rewarming resuscitation technique fields, and in particular to a kind of microwave rewarming recovery instrument for rewarming recovery
Device.
Background technique
With the development of the society, the demand of the raising of especially medical level, cryo-conservation and rewarming resuscitation technique is increasingly
Increase.Cryo-conservation technology relative maturity, for example, can use liquid nitrogen very for such as cell, biological tissue and organ etc.
Long-time freezen protective is carried out well.After freezen protective needed to allow to by rewarming recovery by rewarming recovery sample by
It reuses, but rewarming resuscitation technique is also immature, pertinent instruments do not have substantially, and current rewarming resuscitation technique has microwave method
Rewarming resuscitation technique, laser method rewarming resuscitation technique, 37 DEG C of immersion method rewarming recoveries and magnetic thermal method rewarming resuscitation technique etc..
By rewarming recovery sample in rewarming resuscitation process, when rewarming rate is lower, it will generate recrystallization phenomenon, make
It is come to harm by rewarming recovery sample；When external heat is uneven in by rewarming recovery sample, it will form thermal stress and to quilt
Rewarming recovery sample causes mechanical damage.Therefore, by rewarming recovery sample in rewarming resuscitation process, control heating rate and
Homogeneous heating is the key that guarantee by rewarming recovery sample rewarming Success rate, and still, the relevant technologies, which lack, both can control liter
Warm rate, and can make by the uniformly heated instrument of rewarming recovery sample.
Summary of the invention
In view of this, providing a kind of microwave rewarming resuscitation instruments for rewarming recovery, lacked both with solving the relevant technologies
The problem of can control heating rate, and instrument uniformly heated by rewarming recovery sample can be made.
The present invention adopts the following technical scheme: a kind of microwave rewarming resuscitation instruments for rewarming recovery, comprising: microwave function
Rate emits irradiation structure, microwave source device, temperature-detecting device, control device and liquid nitrogen supplementary device；The microwave source device
For sending microwave to the microwave power transmission irradiation structure；Described in the microwave power transmission irradiation structure will receive
Microwave is emitted or is radiated with TE101 mode of resonance, so that it is 300MHz-500MHz's that the microwave source device, which generates frequency range,
When microwave, it is evenly heated by rewarming recovery sample；The temperature-detecting device is for detecting the microwave power transmission spoke
The temperature by rewarming recovery sample in structure is penetrated, and obtains temperature data；The control device respectively with the temperature
Detection device is connected with the microwave source device, and the temperature data for being sent according to the temperature-detecting device generates the
One control instruction, and control according to first control instruction power of the microwave source device；The liquid nitrogen supplementary device is used
Liquid nitrogen is supplemented into the microwave power transmission irradiation structure in the control operation for receiving user, and according to control operation,
Described heat in ambient enviroment is absorbed by rewarming recovery sample and make described to be gone out by rewarming recovery sample with prevent after freezing
Existing internal-external temperature difference.
Further, the temperature-detecting device be fluorescence type fiber temperature detection device, PT100 temperature sensor or
PT1000 temperature sensor.
Further, the control device be artificial intelligence (Artificial Intelligence, AI) controller, can
The consecutive variations analog quantity controller of programmed logic controller (Programmable Logic Controller, PLC) or closed loop
(Packet Identifier, PID).
It further, further include display device, the display device includes display screen and control panel；The control panel
Control for receiving user operates, and sends the second control instruction to the control device according to control operation；It is described
Display screen is for showing rewarming recovery data.
It further, further include microwave homogeneous area expander；The microwave homogeneous area expander is arranged described micro-
Wave power emits in irradiation structure, for controlling the microwave homogeneous area diameter model in the microwave power transmission irradiation structure
It encloses.
It further, further include light emitting diode (Light Emitting Diode, LED) lamp；The light emitting diode
(Light Emitting Diode, LED) lamp is set on the microwave power transmission irradiation structure, for illuminating described answered
Warm recovery sample.
It further, further include centrifugal fan；The centrifugal fan is set to the microwave power transmission radiation knot
On structure, for replacing the air in the microwave power transmission irradiation structure.
It further, further include rewarming recovery glass container；The rewarming recovery glass container is set to the microwave function
Rate emits in irradiation structure, and communicates with the liquid nitrogen supplementary device, described by rewarming recovery sample for placing.
Further, the rewarming recovery glass container by the through-hole of the rewarming recovery glass container bottom with it is described
Liquid nitrogen supplementary device communicates.
It further, further include wireless device；The wireless device is connect with the control device, for receiving external intelligence
The third control instruction that energy equipment is sent, and the third control instruction is sent to the control device, and be used for institute
It states external smart equipment and sends the rewarming recovery data.
The invention adopts the above technical scheme, the microwave that the microwave power transmission irradiation structure can will receive
Emitted with TE101 mode of resonance or radiated, made described by rewarming recovery sample uniform pickup microwave；Frequency range is 300MHz-
The microwave of 500MHz has good penetration capacity, can penetrate to described by rewarming recovery sample interior, make described by rewarming
Recovery sample inside and outside can be evenly heated；The liquid nitrogen supplementary device can into the microwave power transmission irradiation structure replenisher
Nitrogen is made described by rewarming recovery sample with preventing the heat by rewarming recovery sample absorption ambient enviroment after freezing
Appearance heating rate is greater than the heating rate by rewarming recovery sample interior, makes described by inside and outside the appearance of rewarming recovery sample
The temperature difference to sum up realizes the uniformly heated mesh of sample；In addition, temperature-detecting device can detecte the temperature of sample, temperature is obtained
Data, and temperature data is sent to control device, control device controls the power of microwave source device according to the temperature data,
Realize the purpose of control sample heating rate.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with
It obtains other drawings based on these drawings.
Fig. 1 is a kind of structural representation of microwave rewarming resuscitation instruments for rewarming recovery provided in an embodiment of the present invention
Figure.
Fig. 2 is a kind of structural schematic diagram of microwave power transmission irradiation structure provided in an embodiment of the present invention.
Fig. 3 is each side title schematic diagram of rectangular cavity body in embodiment illustrated in fig. 2.
Fig. 4 is a kind of structural schematic diagram of microwave homogeneous area expander provided in an embodiment of the present invention.
Fig. 5 is a kind of structural schematic diagram of rewarming recovery glass container provided in an embodiment of the present invention.
Fig. 6 is the structural representation of another microwave rewarming resuscitation instruments for rewarming recovery provided in an embodiment of the present invention
Figure.
Fig. 7 is the overlooking structure diagram of the microwave rewarming resuscitation instruments for rewarming recovery corresponding with Fig. 6.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Fig. 1 is a kind of structural representation of microwave rewarming resuscitation instruments for rewarming recovery provided in an embodiment of the present invention
Figure.As shown in Figure 1, the microwave rewarming resuscitation instruments for rewarming recovery are filled by microwave power transmission irradiation structure 11, microwave source
12, temperature-detecting device 13, control device 14 and liquid nitrogen supplementary device 15 is set to form.
Wherein, described by rewarming recovery sample includes cell, biological tissue and organ etc., and microwave source device 12 is used for micro-
Wave power emits irradiation structure 11 and sends microwave；Microwave power transmission irradiation structure 11 for will the microwave that receive with
The transmitting of TE101 mode of resonance or radiation, when so that microwave source device 12 generating the microwave that frequency range is 300MHz-500MHz,
It is evenly heated by rewarming recovery sample；Temperature-detecting device 13 is used to detect the institute in microwave power transmission irradiation structure 11
It states by the temperature of rewarming recovery sample, and obtains temperature data；Control device 14 respectively with temperature-detecting device 13 and microwave source
Device 12 connects, and the temperature data for being sent according to temperature-detecting device 13 generates the first control instruction, and according to institute
State the power of the first control instruction control microwave source device 12；Liquid nitrogen supplementary device 15 is used to receive the control operation of user, and
Into microwave power transmission irradiation structure 11 liquid nitrogen is supplemented according to control operation, described is answered by rewarming with prevent after freezing
Soviet Union's sample absorbs the heat in ambient enviroment and makes described internal-external temperature difference occur by rewarming recovery sample.
Fig. 2 is a kind of structural schematic diagram of microwave power transmission irradiation structure provided in an embodiment of the present invention, such as Fig. 2 institute
Show, microwave power transmission irradiation structure 11 is made of rectangular cavity body 21 and antenna sleeve 22, and antenna sleeve 22 is arranged in square
On 21 upper bottom surface of shape resonant cavity, antenna core 23 is set in antenna sleeve 22, the first end of antenna core 23 by a connector with
The microwave radio coaxial line of microwave source device 12 connects, and the second end of antenna core 23 extends default length to rectangular cavity body 21
Degree, so as to be emitted directly toward in rectangular cavity body 21 by the microwave that antenna core 23 emits.Antenna core 23 and antenna sleeve 22 it
Between filled with for fixed antenna core 23 electromagnetic wave transparent material (not shown in FIG. 2).Fig. 3 is that rectangle is humorous in embodiment illustrated in fig. 2
Each side title schematic diagram of vibration cavity.With reference to Fig. 3,21 long side L of rectangular cavity body, broadside A and high B meet following relational expression,
So that the microwave received is emitted or is radiated with TE101 mode of resonance by microwave power transmission irradiation structure 11.
And A=2B
Microwave source device 12 can be the microwave source device that can generate single-frequency microwave in the prior art, it is preferred that
Microwave source device 12 can be the microwave source device that can generate any frequency between 300MHz to 500MHz in the prior art, example
As used the microwave source device that can generate frequency as 433MHz.Microwave source device 12 includes accessory power supply, microwave source generation dress
Set, microwave radio coaxial line and radiator fan, the accessory power supply are connect with 220V mains supply, for give the microwave source produce
Generating apparatus and radiator fan power supply, the microwave source generating device is by the microwave radio Output with coaxial line microwave, and by institute
It states microwave and is sent to the microwave power transmission irradiation structure 11.Temperature-detecting device 13 can be set in microwave power transmission spoke
It penetrates on the surface of structure 11, the temp probe of temperature monitoring device 13 is penetrated from the outer surface of microwave power transmission irradiation structure 11
The inside of microwave power transmission irradiation structure 11, when the temp probe touches the surface by rewarming recovery sample,
Temperature-detecting device 13 can detect the temperature data by rewarming recovery sample, and the temperature data is sent to
Control device 14 connected to it, is stored with heating parameter in control device 14, such as initial temperature value, final temperature value, rises
The heating parameter such as power of warm required time, heating rate, the corresponding microwave source device 12 of each temperature data, control device 14 connect
After receiving the temperature data, microwave source device 12 connected to it can be controlled according to heating parameter and the temperature data
Power, to realize the purpose for controlling the heating rate by rewarming recovery sample.
Liquid nitrogen supplementary device 15 can be set in liquid nitrogen additional cavity body, and the liquid nitrogen supplement cavity can be and microwave function
The rectangular configuration that rate transmitting irradiation structure 11 is come round.Liquid nitrogen supplementary device 15 can be by glass material container or other are low temperature resistant
The liquid nitrogen supplementary device of material container and polytetrafluoroethylene (PTFE) pipe fitting composition, the glass material container or other low temperature resistant materials are held
Liquid nitrogen is contained in device, the liquid nitrogen additional cavity is located at below microwave power transmission irradiation structure 11, and the glass material holds
Device or other low temperature resistant material containers are placed in the liquid nitrogen additional cavity, described in one end insertion of the polytetrafluoroethylene (PTFE) pipe fitting
In glass material container or other low temperature resistant material containers, the polytetrafluoroethylene (PTFE) pipe fitting other end is inserted into microwave power transmission spoke
It penetrates in structure 11, so that the liquid nitrogen in the glass material container or other low temperature resistant material containers can pass through the polytetrafluoro
Ethylene pipe fitting is risen up into automatically in microwave power transmission irradiation structure 11.Liquid nitrogen supplementary device 15 can also be suitable for the application's
The liquid nitrogen replenishment system of the prior art of microwave rewarming resuscitation instruments for rewarming recovery, the liquid nitrogen replenishment system include suitable
For controlling ball valve, metal hose, attachment device and the polytetrafluoroethylene (PTFE) pipe fitting of liquid nitrogen, one end of the polytetrafluoroethylene (PTFE) pipe fitting
Be inserted into microwave power transmission irradiation structure 11, the other end of the polytetrafluoroethylene (PTFE) pipe fitting by the attachment device with it is described
Connection by metal hose is provided with the ball valve on the metal hose, and external liquid nitrogen can pass through the metal hose and institute
It states polytetrafluoroethylene (PTFE) pipe fitting to flow into microwave power transmission irradiation structure 11, the ball valve is used to adjust the flow velocity of the liquid nitrogen.
In a specific example, microwave source device 12, which is used to send frequency to microwave power transmission irradiation structure 11, is
The microwave of 433MHz, and the power regulating range of microwave source device 12 is 0W-1000W.The temperature detection of temperature-detecting device 13
Range is -200 DEG C -100 DEG C, so that temperature-detecting device 13 can be adapted for being recovered by the entire rewarming of rewarming recovery sample
The temperature detection of journey.Control device 14 can be according to the temperature of the temperature-detecting device 13 received the temperature data sent and setting
The power for spending state modulator microwave source device 12, so that by rewarming recovery sample according to the heating rate of setting during rewarming
Carry out rewarming recovery, wherein user can freely set the heating rate, to meet the different rewarmings by rewarming recovery sample
Recovery requires.Again in specific rewarming resuscitation process, microwave power transmission is put by rewarming recovery sample ready first
In the rectangular cavity body 21 of irradiation structure 11, and mended by the actual needs selection of rewarming recovery sample by liquid nitrogen according to described
It fills and sets 15 and inject liquid nitrogen in real time into rectangular cavity body 21, then the temp probe of temperature-detecting device 13 is affixed on the quilt
The surface of rewarming recovery sample, the time required to initial temperature value, final temperature value, heating are set in control device 14, heating speed
The parameters such as the power bracket of rate and microwave source device 12, the microwave rewarming resuscitation instruments for being eventually used for rewarming recovery start rewarming and answer
Su Suoshu is by rewarming recovery sample.
Rewarming recovery is described to can choose both of which by rewarming recovery sample, and first mode is to have rate heating mode,
Heating rate parameter setting is invalid at this time, and the time required to the heating effectively, user can according to need the setting heating institute
The size to take time reaches setting the time required to the temperature by rewarming recovery sample is from actual temperature by the heating
Final temperature value when, rewarming resuscitation process terminates, the entire rewarming resuscitation process used time be the target heating-up time.It is specific at one
Example in, described in user setting heating the time required to size be two hours, the temperature by rewarming recovery sample from
Actual temperature reaches the final temperature value of setting after two hours rewarmings are recovered, and rewarming resuscitation process terminates.
Second mode is no rate heating mode, and at this moment heating rate parameter setting is effective, nothing the time required to the heating
Effect, user can according to need the size that the heating rate is arranged, and the temperature by rewarming recovery sample is with heating rate
The speed of parameter value heats up, multiple when the temperature by rewarming recovery sample reaches the final temperature value of setting from actual temperature
Warm resuscitation process terminates.In a specific example, heating rate size described in user setting is 0, when rewarming resuscitation process
When beginning, the temperature by rewarming recovery sample is raised to the final temperature of setting with most fast heating rate from actual temperature
Value, rewarming resuscitation process terminate, wherein power decision of the most fast heating rate by microwave source device 12, microwave source dress
Set 12 power it is bigger, the value of the most fast heating rate is bigger.In another specific example, risen described in user setting
Warm rate size is 2 DEG C/min, and when rewarming resuscitation process starts, the temperature by rewarming recovery sample to increase per minute
2 DEG C of heating rate is raised to the final temperature value of setting from actual temperature, and rewarming resuscitation process terminates.Entire rewarming resuscitation process
In, the power of microwave source device 12 is maintained in the power bracket of microwave source device 12 of setting.
The invention adopts the above technical scheme, microwave power transmission irradiation structure 11 can by the microwave received with
The transmitting of TE101 mode of resonance or radiation, make described by rewarming recovery sample uniform pickup microwave；Frequency range is 300MHz-
The microwave of 500MHz has good penetration capacity, can penetrate to described by rewarming recovery sample interior, make described by rewarming
Recovery sample inside and outside can be evenly heated；Liquid nitrogen supplementary device 15 can into the microwave power transmission irradiation structure replenisher
Nitrogen is made described by rewarming recovery sample with preventing the heat by rewarming recovery sample absorption ambient enviroment after freezing
Appearance heating rate is greater than the heating rate by rewarming recovery sample interior, makes described by inside and outside the appearance of rewarming recovery sample
The temperature difference is to sum up realized by the uniformly heated mesh of rewarming recovery sample；In addition, temperature-detecting device 13 can detecte by rewarming
The temperature of recovery sample obtains temperature data, and temperature data is sent to control device 14, and control device 14 is according to the temperature
Degree realizes control by the purpose of rewarming recovery sample heating rate according to the power of control microwave source device 12.
Further, temperature-detecting device 13 be fluorescence type fiber temperature detection device, PT100 temperature sensor or
PT1000 temperature sensor.
Detailed, fluorescence type fiber temperature detection device includes fiber-optic sensor probe, optical fiber cable and demodulator of PM signal PM, institute
It states fiber-optic sensor probe to connect by the optical fiber cable with the demodulator of PM signal PM, the fiber-optic sensor probe is temperature inspection
The temp probe of device 13 is surveyed, the demodulator of PM signal PM is connect with control device 14, and fluorescence type fiber temperature detection device passes through
The fiber-optic sensor probe detection passes through the optical fiber cable by the temperature information of rewarming recovery sample, and by the temperature information
It is transmitted to the demodulator of PM signal PM, the temperature information is converted to the temperature data by the demodulator of PM signal PM, and will be described
Temperature data is sent to control device 14.Fluorescence type optical fiber temperature controller is using Fiber Optic Pyrometer, so without gold
Belong to material and interference is generated to the intracorporal electromagnetic wave of apparatus chamber, is more advantageous to and guarantees the uniform liter by rewarming recovery sample
Temperature, to guarantee the survival rate by rewarming recovery sample.
PT100 temperature sensor is made of sensor and signal adapter, and signal adapter is mainly by measuring unit, signal
Processing and converting unit composition, the sensor of PT100 temperature sensor are PT100 thermal resistance.PT1000 temperature sensor also by
Sensor and signal adapter composition, the sensor of PT1000 temperature sensor are PT1000 thermal resistance.PT100 temperature sensor
Have the advantages that measurement accuracy is high with PT1000 temperature sensor, improves the measurement temperature data by rewarming recovery sample
Accuracy.
Further, control device 14 is the consecutive variations of artificial intelligence controller, programmable logic controller (PLC) or closed loop
Analog quantity controller.
Detailed, the consecutive variations analog quantity controller of artificial intelligence controller, programmable logic controller (PLC) or closed loop are equal
It can be according to ratio, integral, the differential control measure of the heating actual conditions Auto-matching PID by rewarming recovery sample
According to controlling the power of microwave source device 12 according to the temperature data by rewarming recovery sample to realize, meet difference
The heating demand by rewarming recovery sample.In addition, artificial intelligence controller, programmable logic controller (PLC) or closed loop it is continuous
Change modeling amount controller can also control the heating rate by rewarming recovery sample, make it is described by rewarming recovery sample by
It heats up according to preset heating rate, improves the rewarming Success rate by rewarming recovery sample.
Further, the microwave rewarming resuscitation instruments for rewarming recovery further include display device, the display device packet
Include display screen and control panel；The control panel is used to receive the control operation of user, and is operated according to the control to control
Device 14 processed sends the second control instruction；The display screen is for showing rewarming recovery data.
Specifically, second control instruction is to control the control instruction of the working condition of control device 14, such as be arranged
The running parameter etc. of control device 14.The control panel is used to receive the input operation of user, and is grasped according to the input of user
Make to input corresponding data, such as input temp, time, power, heating rate etc., and the setting behaviour for receiving user
Make, and operated according to the setting of user to controller and send corresponding setting instruction, such as uses rate heating function command, protects
Setting parameter instruction etc. is deposited, controller can be control device 14, be also possible to show with what display screen and control device 14 were connect
Have the controller of technology, be stored with computer-controlled program in the controller so that the controller have setting, input,
The functions such as preservation.When the controller is the controller for the prior art connecting with display screen and control device 14, the control
Panel processed sends the second control instruction to control device 14 by the controller.The rewarming recovery data include described answered
It is the actual temperature of warm recovery sample, described by the target temperature of rewarming recovery sample, the power bracket of microwave source device 12, microwave
Actual power, target heating-up time, practical heating-up time, heating rate of source device 12 etc..Realizing knows that user easily
The purpose of the heating data of the ramp case of rewarming recovery sample described in road and the acquisition rewarming recovery sample, and make user
It is easy to control the purpose of control device 14.
Further, the microwave rewarming resuscitation instruments for rewarming recovery, further include microwave homogeneous area expander, described
Microwave homogeneous area expander is arranged in the microwave power transmission irradiation structure, for controlling the microwave power transmission spoke
Penetrate the microwave homogeneous area diameter range in structure.
Fig. 4 is a kind of structural schematic diagram of microwave homogeneous area expander provided in an embodiment of the present invention.It is micro- with reference to Fig. 4
The material of the uniform expander of wave is not absorb and penetrate microwave material, such as can be glass.Microwave homogeneous area expander is
Hydrostatic column, inside be contained with water, range is indicated on side, by controlling in the microwave homogeneous area expander
The water level height of water can control the diameter range of microwave homogeneous area in microwave power transmission irradiation structure 11, i.e., the described microwave
The diameter model of the water level height and microwave homogeneous area in microwave power transmission irradiation structure 11 of water in homogeneous area expander
Correlation is enclosed, the water being contained in the microwave homogeneous area expander forms a cylinder shape medium.When electric field and the cylinder
Electric field strength formula when the axis of medium is perpendicular, inside and outside the cylinder shape medium are as follows:
Electric field strength in the cylinder shape medium are as follows:
Electric field strength in the cylinder shape medium are as follows:
Wherein, ε1=εrε0, ε1For the dielectric constant of the cylinder shape medium, ε0For permittivity of vacuum, εrFor opposite Jie
Electric constant, exRefer to the unit vector in the x-axis direction in plane right-angle coordinate, erRefer in polar coordinate system on polar diameter direction
Unit vector, E0Emit the electric field strength when cylinder shape medium being not added in irradiation structure 11 for wave power.A is microwave function
Rate emits side length of the irradiation structure 11 in x-axis, the polar coordinates of (r, φ) any point, wherein plane right-angle coordinate institute
Plane it is parallel with the cross section of the cylinder shape medium, the corresponding relationship of polar coordinate system and plane right-angle coordinate are as follows: two
The coordinate origin of coordinate system is overlapped, and using the z-axis of plane right-angle coordinate as the polar axis of polar coordinate system.Computer is obtaining as a result,
After getting diameter and the height of the cylinder shape medium, it is uniform that microwave in microwave power transmission irradiation structure 11 can be calculated
The diameter range in region, therefore, user can select the suitable cylinder according to the size by rewarming recovery sample
The diameter and height of medium, namely selected according to the size by rewarming recovery sample in the microwave homogeneous area expander
The water level height of middle injection.
Further, the microwave rewarming resuscitation instruments for rewarming recovery, further include LED light lamp；Described luminous two
Pole pipe lamp is set on microwave power transmission irradiation structure 11, described by rewarming recovery sample for illuminating.
Specifically, to can be set the side wall in wave power transmitting irradiation structure 11 outside upper for the LED light lamp, it can be with
It is powered by battery or power line.The spectrum of LED light lamp is simple, and is cold light source, to by the rewarming of rewarming recovery sample
Recovery influence is smaller, improves by the rewarming Success rate of rewarming recovery sample.
Further, the microwave rewarming resuscitation instruments for rewarming recovery, further include centrifugal fan；The centrifugal wind
Machine is set on microwave power transmission irradiation structure 11, for replacing the air in microwave power transmission irradiation structure 11.
Detailed, the centrifugal fan is centrifugal fan in the prior art, can be set and sends out in microwave power
It penetrates on the side wall of irradiation structure 11, such as the vertex of the rear wall of microwave power transmission irradiation structure 11 is set.It is centrifugal
Blower has the advantages that work efficiency is high, is more advantageous to and keeps with fresh air, clean in microwave power transmission irradiation structure 11
With it is sterile.
Further, the microwave rewarming resuscitation instruments for rewarming recovery, further include rewarming recovery glass container；It is described multiple
Warm recovery glass container is set in microwave power transmission irradiation structure 11, and is communicated with liquid nitrogen supplementary device 15, for placing
It is described by rewarming recovery sample.
Specifically, according to the difference by rewarming recovery sample, the shape of the rewarming recovery glass container also not phase
Together, for example, when it is described by rewarming recovery sample be cell when, the shape of the rewarming recovery glass container can be tubbiness, work as institute
It states by rewarming recovery sample whens being organ etc., the shape of the rewarming recovery glass container can be with hypocrateriform.The rewarming recovery
Glass container can be located on the bottom surface inside microwave power transmission irradiation structure 11, and user described is answered by rewarming taking
When Soviet Union's sample, it is only necessary to take and hold the rewarming recovery glass container by rewarming recovery sample, eliminate volume
It is the step of outer transfer recovery sample by rewarming, easy to use.The rewarming recovery glass holds and 15 phase of liquid nitrogen supplementary device
Logical, liquid nitrogen supplementary device 15 directly can supplement liquid nitrogen into rewarming recovery glass appearance, so that described by rewarming recovery sample
In the environment full of liquid nitrogen.The present embodiment, which realizes, conveniently to be taken described by rewarming recovery sample, keeps user easy to use
Purpose, and the purpose for making the ambient enviroment by rewarming recovery sample sufficiently be full of liquid nitrogen.
Further, through-hole and liquid nitrogen that the rewarming recovery glass container passes through the rewarming recovery glass container bottom
Supplementary device 15 communicates.
Fig. 5 is a kind of structural schematic diagram of rewarming recovery glass container provided in an embodiment of the present invention.It is described with reference to Fig. 5
The bottom of rewarming recovery glass container is provided with through-hole 51, and through-hole 51 can be set in the rewarming recovery glass container bottom
Center position is provided with sample disc 52 in the top position of through-hole 51, and sample disc 52 is fixed on the rewarming recovery glass and holds
On the side wall of device, sample disc 52 can be the reticular structure with mesh 53, described by rewarming recovery sample for placing.Liquid nitrogen
After being flowed out by through-hole 51, then the mesh 53 passed through in sample disc 52 flows to the rewarming recovery glass container.The present embodiment is kept away
The process for flowing into liquid nitrogen in the rewarming recovery glass container is exempted from, realizing makes the rewarming
The simple purpose of recovery glass container structure.
Further, the microwave rewarming resuscitation instruments for rewarming recovery, further include wireless device；The wireless device with
Control device 14 connects, and sends out for receiving the third control instruction of external smart equipment transmission, and by the third control instruction
Control device 14 is given, and for sending the rewarming recovery data to the external smart equipment.
Detailed, the wireless device can be blue-tooth device or WiMAX (WIreless-FIdelity, WI-FI)
Device etc..The external smart equipment can be smart phone or computer etc..The wireless device can be with the external smart
Equipment wireless communication, user can remotely control control device 14 by the external smart equipment, and then remotely control use
In the microwave rewarming resuscitation instruments of rewarming recovery, user-friendly purpose is realized.
Fig. 6 is the structure for the microwave rewarming resuscitation instruments that the another kind that further embodiment of this invention provides is recovered for rewarming
Schematic diagram.Fig. 7 is the overlooking structure diagram of the microwave rewarming resuscitation instruments for rewarming recovery corresponding with Fig. 6.With reference to Fig. 6
And Fig. 7, for rewarming recovery microwave rewarming resuscitation instruments include microwave power transmission irradiation structure 11, microwave source device 12,
Temperature-detecting device 13, control device 14, liquid nitrogen supplementary device 15, display device 61, LED light 62, microwave homogeneous area expand
Device 63, rewarming recovery glass container 64, microwave supplement cavity 65 and centrifugal fan 72.
Wherein, microwave source device 12 passes through the antenna sleeve 22 of microwave cable line 66 and microwave power transmission irradiation structure 11
Interior antenna core 23 connects, for sending microwave into microwave power transmission irradiation structure 11.The optical fiber of temperature-detecting device 13
Line 71 extends in microwave power transmission irradiation structure 11, and the end of optical fiber cable 71 is provided with temp probe, when the temperature is visited
When head touches the recovery sample by rewarming, temperature-detecting device 13 can get described answered by the temp probe
The temperature data of warm recovery sample.Control device 14 respectively with microwave source device 12, temperature-detecting device 13 and display device 61
Line connection；LED light 62 is arranged in 11 rear wall center position of microwave power transmission irradiation structure；The setting of centrifugal fan 72 exists
One vertex of microwave power transmission irradiation structure 11；Microwave homogeneous area expander 63 is placed on microwave power transmission radiation
One corner of structure 11；First through hole, rewarming are provided at the bottom centre position of microwave power transmission irradiation structure 11
The second through-hole is provided at the bottom centre position of recovery glass container 64, the liquid nitrogen supplement dress being placed in microwave supplement cavity 65
15 are set by the first through hole and described second by supplementing liquid nitrogen into microwave power transmission irradiation structure 11.
What the present embodiment was implemented on the basis of the above embodiments in fact, have the corresponding specific structure of above-described embodiment and has
Beneficial effect, this will not be repeated here.
It is understood that same or similar part can mutually refer in the various embodiments described above, in some embodiments
Unspecified content may refer to the same or similar content in other embodiments.
It should be noted that in the description of the present invention, term " first ", " second " etc. are used for description purposes only, without
It can be interpreted as indication or suggestion relative importance.In addition, in the description of the present invention, unless otherwise indicated, the meaning of " multiple "
Refer at least two.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
Centainly refer to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be any
One or more embodiment or examples in can be combined in any suitable manner.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, modifies, replacement and variant.
Claims (10)
1. a kind of microwave rewarming resuscitation instruments for rewarming recovery characterized by comprising microwave power transmission radiation knot
Structure, microwave source device, temperature-detecting device, control device and liquid nitrogen supplementary device；
The microwave source device is used to send microwave to the microwave power transmission irradiation structure；
The microwave that the microwave power transmission irradiation structure is used to receive is emitted or is radiated with TE101 mode of resonance,
When so that the microwave source device generating the microwave that frequency range is 300MHz-500MHz, by rewarming recovery sample by uniform
Heating；
The temperature-detecting device is used to detect described in the microwave power transmission irradiation structure by rewarming recovery sample
Temperature, and obtain temperature data；
The control device is connect with the temperature-detecting device and the microwave source device respectively, for being examined according to the temperature
It surveys the temperature data that device is sent and generates the first control instruction, and the microwave source is controlled according to first control instruction
The power of device；
The liquid nitrogen supplementary device is used to receive the control operation of user, and is sent out according to control operation to the microwave power
It penetrates and supplements liquid nitrogen in irradiation structure, made with preventing the heat by rewarming recovery sample absorption ambient enviroment after freezing
It is described that internal-external temperature difference is occurred by rewarming recovery sample.
2. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that the temperature inspection
Survey device is fluorescence type fiber temperature detection device, PT100 temperature sensor or PT1000 temperature sensor.
3. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that the control dress
It is set to the consecutive variations analog quantity controller of artificial intelligence controller, programmable logic controller (PLC) or closed loop.
4. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that further include display
Device, the display device include display screen and control panel；
The control panel is used to receive the control operation of user, and according to control operation to control device transmission the
Two control instructions；The display screen is for showing rewarming recovery data.
5. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that further include microwave
Homogeneous area expander；
The microwave homogeneous area expander is arranged in the microwave power transmission irradiation structure, for controlling the microwave function
Rate emits the microwave homogeneous area diameter range in irradiation structure.
6. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that further include shining
Diode lights；
The LED light lamp is set on the microwave power transmission irradiation structure, described by rewarming recovery sample for illuminating
Product.
7. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that further include centrifugation
Formula blower；
The centrifugal fan is set on the microwave power transmission irradiation structure, for replacing the microwave power transmission spoke
Penetrate the air in structure.
8. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that further include rewarming
Recovery glass container；
The rewarming recovery glass container is set in the microwave power transmission irradiation structure, and with the liquid nitrogen supplementary device
It communicates, it is described by rewarming recovery sample for placing.
9. the microwave rewarming resuscitation instruments according to claim 8 for rewarming recovery, which is characterized in that the rewarming is multiple
Soviet Union's glass container is communicated by the through-hole of the rewarming recovery glass container bottom with the liquid nitrogen supplementary device.
10. the microwave rewarming resuscitation instruments according to claim 1 for rewarming recovery, which is characterized in that further include nothing
Line apparatus；
The wireless device is connect with the control device, for receiving the third control instruction of external smart equipment transmission, and
The third control instruction is sent to the control device, and multiple for sending the rewarming to the external smart equipment
Soviet Union's data.
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