CN110420673A - A kind of micro-fluidic device and its driving method, microfluidic system - Google Patents
A kind of micro-fluidic device and its driving method, microfluidic system Download PDFInfo
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- CN110420673A CN110420673A CN201910748309.1A CN201910748309A CN110420673A CN 110420673 A CN110420673 A CN 110420673A CN 201910748309 A CN201910748309 A CN 201910748309A CN 110420673 A CN110420673 A CN 110420673A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
Abstract
This application discloses a kind of micro-fluidic device and its driving methods, microfluidic system, to solve the problems, such as that drop is difficult to across electrode gap.A kind of micro-fluidic device provided by the embodiments of the present application, the micro-fluidic device include: first substrate and the second substrate that be opposite and setting；Drop accommodating space is constituted between the first substrate and the second substrate；The first substrate includes: the first electrode of array arrangement, and the second substrate includes: the second electrode of array arrangement；In at least one orientation of the first electrode, the gap between gap and the second electrode between the first electrode is non-overlapping；The first electrode and the second electrode are configured as: being applied voltage to the first electrode and the second electrode, moved with controlling drop between the first substrate and the second substrate.
Description
Technical field
This application involves microfluidic art more particularly to a kind of micro-fluidic devices and its driving method, micro-fluidic system
System.
Background technique
Microflow control technique can apply the side such as drop separation, fusion, detection in the multiple fields such as medicine, chemistry, biology
Face.The manipulation that micro-fluidic device drives drop is realized by dielectric wetting effect, mainly passes through driving electrodes to leaning on
Nearly electrode side drop applies electric field, changes droplet surface charge distribution state, in turn results in the change of drop side surface tension and draws
Hydrophobic angle variation is played, it is final to realize that drop is mobile.Current micro-fluidic device scheme is as shown in Figure 1, micro-fluidic device includes glass
Glass substrate 1 and cover board 3, and the multiple driving electrodes 2 being arranged on glass substrate 1 have gap between each driving electrodes, when
Drop 4 is when being moved to electrode edge, it is difficult to continue to move to across the gap between electrode.
To sum up, the discontinuous of drop movable passageway is caused in the micro-fluidic device of the prior art, the gap between electrode, in turn
Drop moving disorder is caused, drop is difficult to across electrode gap.
Summary of the invention
The embodiment of the present application provides a kind of micro-fluidic device and its driving method, microfluidic system, to solve drop
It is difficult to across electrode gap problem.
A kind of micro-fluidic device provided by the embodiments of the present application, the micro-fluidic device include: the first base that is opposite and setting
Plate and the second substrate；Drop accommodating space is constituted between the first substrate and the second substrate；The first substrate includes:
The first electrode of array arrangement, the second substrate include: the second electrode of array arrangement；At least the one of the first electrode
In a orientation, the gap between gap and the second electrode between the first electrode is non-overlapping；Described first
Electrode and the second electrode are configured as: being applied voltage to the first electrode and the second electrode, existed with controlling drop
It is moved between the first substrate and the second substrate.
The first substrate and the second substrate that micro-fluidic device provided by the embodiments of the present application is set due to opposite are provided with
The electrode for driving drop mobile, and at least one orientation of electrode, between the first electrode of first substrate
Gap and gap between the second electrode of the second substrate it is non-overlapping, that is to say, that first electrode and second electrode
It is staggered, at least one orientation of electrode, the gap between second electrode has overlapping, the first electricity with first electrode
Gap between pole have with second electrode it is overlapping, in this way, having with gap overlapping when drop is needed across gap between electrode
Electrode drop can be driven, so as to control drop across gap.
Optionally, the first electrode is arranged along first direction and second direction, and the second electrode is along first direction
And second direction arrangement；In said first direction, the gap between the first electrode and between the second electrode
Gap is non-overlapping；And/or in this second direction, the gap between the first electrode and between the second electrode
Gap it is non-overlapping.
Optionally, the first electrode is identical with the shape of the second electrode and size.
Optionally, the first electrode and the second electrode are block type electrode.
Optionally, the center of the first electrode is fallen into the gap between the second electrode, and the second electrode
Center fall into the gap between the first electrode.
Optionally, the first substrate further include: the first driving electricity for corresponding and being electrically connected with the first electrode
Road；The second substrate further include: the second driving circuit for corresponding and being electrically connected with the second electrode.
A kind of driving method of micro-fluidic device provided by the embodiments of the present application, which comprises
Determine the initial position and movement routine of drop；
It is determined according to the initial position and the movement routine and controls the mobile first electrode of the drop and the second electricity
Pole provides voltage signal for the first electrode and the second electrode, prolongs the movement routine movement to control drop.
Optionally, the mobile first electrode of the drop and the second electricity are controlled according to the initial position and the movement routine
Pole specifically includes:
According to the movement routine, the corresponding first electrode row of the movement routine and second electrode row are determined, alternatively,
According to the movement routine, the corresponding first electrode column of the movement routine and second electrode column are determined；
Also, driving drop movement is determined in position of the initial position towards moving direction one side edge according to drop
First electrode；
Voltage signal is provided for the first electrode and the second electrode, prolongs the movement routine shifting to control drop
It is dynamic, it specifically includes:
Since first electrode, on the direction along the movement routine, it is moved to according to the drop described
The sequence of first electrode and the second electrode successively alternately applies voltage to the first electrode and the second electrode.
Optionally, mobile according to the drop on the direction along the movement routine since first electrode
To the sequence of the first electrode and the second electrode, successively the first electrode and the second electrode are successively alternately applied
Making alive specifically includes:
When the edge of the drop is moved to any first electrode, to first electrode application voltage, and right
While the first electrode applies one preset duration of voltage regulation, stop to in the movement routine opposite direction with described the
The adjacent second electrode of one electrode applies voltage；
Alternatively, the edge when the drop is moved to any second electrode, voltage is applied to the second electrode, and
To the second electrode apply one preset duration of voltage regulation while, stop to in the movement routine opposite direction with institute
It states the adjacent first electrode of second electrode and applies voltage.
A kind of microfluidic system provided by the embodiments of the present application, including above-mentioned microfluidic devices provided by the embodiments of the present application
Part.
Detailed description of the invention
In order to more clearly explain the technical solutions in the embodiments of the present application, make required in being described below to embodiment
Attached drawing is briefly introduced, it should be apparent that, the drawings in the following description are only some examples of the present application, for this
For the those of ordinary skill in field, without creative efforts, it can also be obtained according to these attached drawings other
Attached drawing.
Fig. 1 is the structural schematic diagram of prior art micro-fluidic device；
Fig. 2 is a kind of structural schematic diagram of micro-fluidic device provided by the embodiments of the present application；
Fig. 3 is the structural schematic diagram of another micro-fluidic device provided by the embodiments of the present application；
Fig. 4 is the structural schematic diagram of another micro-fluidic device provided by the embodiments of the present application；
Fig. 5 is the structural schematic diagram of another micro-fluidic device provided by the embodiments of the present application；
Fig. 6 is a kind of schematic diagram of the driving method of micro-fluidic device provided by the embodiments of the present application；
Fig. 7 is the schematic diagram of the driving method of another micro-fluidic device provided by the embodiments of the present application；
Fig. 8 is a kind of corresponding timing of driving method of micro-fluidic device as shown in Figure 7 provided by the embodiments of the present application
Figure；
Fig. 9 is the schematic diagram of the driving method of another micro-fluidic device provided by the embodiments of the present application；
Figure 10 is a kind of corresponding timing of driving method of micro-fluidic device as shown in Figure 9 provided by the embodiments of the present application
Figure.
Specific embodiment
The embodiment of the present application provides a kind of micro-fluidic device, as shown in Fig. 2, the micro-fluidic device include: it is opposite and
The first substrate 5 and the second substrate 6 set；Drop accommodating space 7 is constituted between the first substrate 5 and the second substrate 6；
The first substrate 5 includes: the first electrode 8 of array arrangement, and the second substrate 6 includes the second electrode 9 of array arrangement；In
In at least one orientation of the first electrode 8, gap 10 between the first electrode 8 and the second electrode 9 it
Between gap 11 it is non-overlapping；The first electrode 8 and the second electrode 9 are configured as: to the first electrode 8 and described
Second electrode 9 applies voltage, is moved with controlling drop 4 between the first substrate 5 and the second substrate 6.
The first substrate and the second substrate that micro-fluidic device provided by the embodiments of the present application is set due to opposite are provided with
The electrode for driving drop mobile, and at least one orientation of electrode, between the first electrode of first substrate
Gap and gap between the second electrode of the second substrate it is non-overlapping, that is to say, that first electrode and second electrode
It is staggered, at least one orientation of electrode, the gap between second electrode has overlapping, the first electricity with first electrode
Gap between pole have with second electrode it is overlapping, in this way, having with gap overlapping when drop is needed across gap between electrode
Electrode drop can be driven, so as to control drop across gap.
Optionally, micro-fluidic device as shown in Figure 2 provided by the embodiments of the present application, first substrate 5 further include: array base
Plate 12, dielectric layer 13 and hydrophobic layer 14, first electrode 8 are located at side of the array substrate 12 towards the second substrate 6, dielectric layer 13
Side positioned at first electrode 8 towards the second substrate 6, hydrophobic layer 14 are located at side of the dielectric layer 13 towards the second substrate 6；First
Substrate 6 further include: array substrate 12, dielectric layer 13 and hydrophobic layer 14, second electrode 9 are located at array substrate 12 towards the first base
The side of plate 5, dielectric layer 13 are located at side of the first electrode 8 towards first substrate 5, and hydrophobic layer 14 is located at dielectric layer 13 towards
The side of one substrate 5.
Optionally, the first electrode is arranged along first direction and second direction, and the second electrode is along first direction
And second direction arrangement；In said first direction, the gap between the first electrode and between the second electrode
Gap is non-overlapping；And/or in this second direction, the gap between the first electrode and between the second electrode
Gap it is non-overlapping.
As shown in Fig. 3~Fig. 5, first electrode 8 is arranged along first direction X and second direction Y, and second electrode 9 is along first
Direction X and second direction Y arrangement.In Fig. 3, in a first direction the gap between the first electrode adjacent on X with the
Gap on one direction X between the adjacent second electrode is non-overlapping.In Fig. 4, second direction Y it is adjacent described first
Gap between electrode and the gap between the adjacent second electrode of second direction Y are non-overlapping.In Fig. 5, first
Between between gap and the second electrode adjacent on X in a first direction on the X of direction between the adjacent first electrode
Gap is non-overlapping, and the gap between the adjacent first electrode of second direction Y it is adjacent in second direction Y described in
Gap between second electrode is non-overlapping.
One direction drop may be implemented across electricity in micro-fluidic device as shown in Figure 3, Figure 4 provided by the embodiments of the present application
Clearance between poles.Micro-fluidic device as shown in Figure 5 provided by the embodiments of the present application can realize drop across electricity in both direction
Clearance between poles.
It should be noted that in Fig. 3~Fig. 5, in order to clearly show the positional relationship of first electrode and second electrode, with
The region that Regional Representative's second electrode 9 that dotted line surrounds covers.
Optionally, in Fig. 3~Fig. 5, the first electrode 8 is identical with the shape of the second electrode 9 and size.
Optionally, in Fig. 3~Fig. 5, between the gap size and the second electrode 9 between the first electrode 8 between
Gap is equal sized.
Optionally, in Fig. 3~Fig. 5, the first electrode 9 and the second electrode 8 are block type electrode.
For example, the side length of block type electrode be 200 microns, block type electrode with a thickness of 20 microns, between block type electrode between
Gap is 10 microns.In practical applications, size of the drop in micro-fluidic device accommodating space on electrode side length direction can be with
Greater than electrode side length, electrode side length might be less that.
Optionally, in Fig. 3~Fig. 5, the center of the first electrode 8 is fallen into the gap between the second electrode 9, and
The center of the second electrode 9 is fallen into the gap between the first electrode 8.
In this way, the symmetry axis that the gap between the adjacent first electrode extends in a second direction in a first direction,
The symmetrical overlapping of axles extended in a second direction with second electrode；Gap between the adjacent first electrode in a second direction
The symmetry axis extended in a first direction, the symmetrical overlapping of axles extended in a first direction with second electrode.
Optionally, the first substrate further include: the first driving electricity for corresponding and being electrically connected with the first electrode
Road；
The second substrate further include: the second driving circuit for corresponding and being electrically connected with the second electrode.
First driving circuit for example may include: the first film transistor in the array substrate of first substrate, and first
Data line and the first scan line.First film transistor and first electrode correspond, the grid of first film transistor with
The electrical connection of first scan line, the source electrode of first film transistor are electrically connected with the first data line, the drain electrode of first film transistor
It is electrically connected with first electrode.
Second driving circuit for example may include: the second thin film transistor (TFT) in the array substrate of the second substrate, and second
Data line and the second scan line.Second thin film transistor (TFT) and second electrode correspond, the grid of the second thin film transistor (TFT) with
The electrical connection of second scan line, the source electrode of the second thin film transistor (TFT) are electrically connected with the second data line, the drain electrode of the second thin film transistor (TFT)
It is electrically connected with second electrode.
Optionally, the first scan line has overlapping with first electrode, and the first data line has overlapping with first electrode；Second scanning
Line has overlapping with second electrode, and the second data line has overlapping with second electrode.
So as to reduce the gap between first electrode and reduce the gap between second electrode.
Optionally, micro-fluidic device provided by the embodiments of the present application further includes droplet position detection unit.So as to examine
The position of drop and the position of drop edge are surveyed, so as to determine its shifting of control according to the position of droplet position and its edge
Dynamic first electrode and second electrode.
Based on the same inventive concept, the embodiment of the present application also provides a kind of driving methods of above-mentioned micro-fluidic device, such as
Shown in Fig. 6, which comprises
S101, the initial position and movement routine for determining drop；
S102, it is determined according to the initial position and the movement routine and controls the mobile first electrode of the drop and the
Two electrodes provide voltage signal for the first electrode and the second electrode, prolong the movement routine movement to control drop.
Optionally, step S102 controls the first mobile electricity of the drop according to the initial position and the movement routine
Pole and second electrode, specifically include:
S1021, according to the movement routine, determine the corresponding first electrode row of the movement routine and second electrode
Row, alternatively, determining the corresponding first electrode column of the movement routine and second electrode column according to the movement routine；
S1022, according to drop in position of the initial position towards moving direction one side edge, determine that driving drop is mobile
First electrode.
It should be noted that droplet position detection unit can be examined when micro-fluidic device includes droplet position detection unit
The initial position of drop is surveyed, and then determines movement routine, and determines first electrode row corresponding with movement routine and the second electricity
It extremely goes, or determines first electrode column corresponding with movement routine and second electrode column, and it is corresponding to can detecte drop edge
First electrode and second electrode position.
Optionally, step S102 provides voltage signal for the first electrode and the second electrode, is prolonged with controlling drop
The movement routine is mobile, specifically includes:
S1023, since first electrode, it is mobile according to the drop on the direction along the movement routine
To the sequence of the first electrode and the second electrode, electricity is alternately successively applied to the first electrode and the second electrode
Pressure.
Optionally, step S1023 is since first electrode, on the direction along the movement routine, according to institute
The sequence that drop is moved to the first electrode and the second electrode is stated, successively to the first electrode and the second electrode
Successively alternately apply voltage, specifically include:
When the edge of the drop is moved to any first electrode, to first electrode application voltage, and right
While the first electrode applies one preset duration of voltage regulation, stop to in the movement routine opposite direction with described the
The adjacent second electrode of one electrode applies voltage；
When the edge of the drop is moved to any second electrode, to second electrode application voltage, and right
While the second electrode applies one preset duration of voltage regulation, stop to in the movement routine opposite direction with described the
The adjacent first electrode of two electrodes applies voltage.
The driving method of micro-fluidic device provided by the embodiments of the present application, since first mobile electrode of driving drop
Apply voltage, applies the edge of alive electrode when drop is moved to, it can be to next electricity on movement routine direction
Pole starts to apply voltage；By taking the electrode of current applied voltage is first electrode as an example, then when drop is moved to the first electrode side
It keeps applying the first electrode voltage when edge, while to opposite with the first electrode and to have overlapping second electrode to apply electric
Pressure, after applying voltage preset duration to the second electrode, only applying voltage to second electrode can drive drop mobile, can
To stop applying voltage to first electrode, and so on, until drop is moved to target position along movement routine.
Have with row serial number in micro-fluidic device and column serial number first electrode and second electrode all the same it is overlapping, and with first
The identical second electrode of electrode sequence number is located at the first electrode for the side in movement routine direction, according to close to described
The position of the drop edge of movement routine side determines the position for first electrode for driving the drop mobile, specifically
Include:
According to the position of the drop edge close to movement routine side, the corresponding first electrode of drop edge and second are determined
The serial number of electrode；
If the first electrode is identical with the serial number of the second electrode, moved the first electrode as driving drop
First dynamic electrode；
If the serial number of the first electrode and the second electrode is not identical, using the second electrode as driving drop
First mobile electrode.
It should be noted that when the extending direction of movement routine is identical as the line direction of first electrode and second electrode,
The serial number column serial number for determining the corresponding first electrode of drop edge and second electrode, when the extending direction of movement routine and first
When electrode is identical with the column direction of second electrode, the serial number row sequence of the corresponding first electrode of drop edge and second electrode is determined
Number.
By taking movement routine extending direction is identical as the line direction of the first electrode as an example, corresponding first electricity of movement routine
Extremely row includes n first electrode, and each first electrode is denoted as Ai, and 1≤i≤n, the corresponding second electrode row of movement routine includes n
A second electrode, each second electrode are denoted as Bi, 1≤i≤n；I also corresponds to the column sequence of first electrode and second electrode simultaneously
Number；As shown in fig. 7, in initial position, the edge of drop 4 is between first electrode A2 and second electrode B2, i.e. second electrode
It is identical with the column serial number of first electrode, therefore first electrode A2 is first electrode for driving drop 4 mobile, therefore described in control
The mobile first electrode of drop and second electrode are successively are as follows: first electrode A2, second electrode B2, first electrode A3, second electrode
B3 ..., first electrode An, second electrode Bn, voltage is successively alternately applied to the first electrode and the second electrode
The step of include:
S201, voltage is applied to first electrode A2；
S202, to first electrode A2 apply voltage keep the second preset duration t1 after, drop 4 is moved to first electrode A2's
Edge keeps applying first electrode A2 voltage at this time, while applying voltage to second electrode B2；
S203, apply voltage to second electrode B2 after the first preset duration t2, stop applying electricity to first electrode A2
Pressure；Drop 4 spans the gap between first electrode A2 and first electrode A3 under the action of second electrode B2；
S204, to second electrode B2 apply voltage keep the second preset duration t1 after, drop 4 is moved to second electrode B2's
Edge keeps applying second electrode B2 voltage at this time, while applying voltage to first electrode A3.
It is subsequent, voltage is applied after the first preset duration t2 to first electrode A3, stops applying electricity to second electrode B2
Pressure.
It should be noted that in order to clearly show to the driving method of micro-fluidic device provided by the embodiments of the present application such as
What alternately applies voltage to first electrode and second electrode, and alive electrode is applied in the electrode representative of filled black in Fig. 7.And
And the step of drop 4 is moved upwards up to first electrode A3 along movement routine side is only shown in Fig. 7, it is subsequent to be moved along movement routine
It does not show that.In addition, along movement routine extending direction, the size of drop 4 is greater than the size of first electrode 8 in Fig. 7, having
The size of drop 4 might be less that the size of first electrode 8 when body is implemented.
It is corresponding with driving method shown in Fig. 7 that alive timing diagram such as Fig. 8 institute is applied to first electrode and second electrode
Show, successively to first electrode A2, second electrode B2, first electrode A3, second electrode B3 ..., first electrode An, second electricity
Pole Bn applies voltage, starts to apply voltage to next electrode after applying two preset duration t1 of voltage regulation to each electrode, and
In addition to first applies the voltage of electrode, stop applying a upper electrode after applying one preset duration t2 of voltage regulation to each electrode
Making alive.
Still have with row serial number in micro-fluidic device and column serial number first electrode and second electrode all the same it is overlapping, and with
The identical second electrode of one electrode sequence number is located at the first electrode for the side in movement routine direction, optionally, root
According to the position of the drop edge close to the movement routine side, first electrode for driving the drop mobile is determined
Position specifically includes:
According to the position of the drop edge close to movement routine side, the corresponding first electrode of drop edge and second are determined
The serial number of electrode；
If the first electrode is identical with the serial number of the second electrode, and the drop edge along movement routine direction
The edge of first electrode is not reached, then first electrode that the first electrode is mobile as driving drop；
If the first electrode is identical with the serial number of the second electrode, and the drop edge along movement routine direction
The edge of first electrode is reached, then first electrode that the second electrode is mobile as driving drop；
If the serial number of the first electrode and the second electrode is not identical, and the drop side along movement routine direction
Edge does not reach the edge of second electrode, then first electrode that the second electrode is mobile as driving drop；
If the serial number of the first electrode and the second electrode is not identical, and the drop side along movement routine direction
Edge reaches the edge of second electrode, then first electrode that the first electrode is mobile as driving drop.
As shown in figure 9, the size of drop 4 is less than the size of first electrode 8, first along the direction that movement routine extends
Beginning position, the edge of drop 4 is between first electrode A2 and second electrode B2, and the drop along movement routine direction
4 edges reach the edge of first electrode A2, therefore second electrode B2 is first electrode for driving drop 4 mobile, therefore is controlled
The mobile first electrode of the drop and second electrode are followed successively by, second electrode B2, first electrode A3, second electrode
B3 ..., first electrode An, second electrode Bn, voltage is successively alternately applied to the first electrode and the second electrode
The step of include:
S301, voltage is applied to second electrode B2；
S302, second electrode B2 is applied after voltage keeps the second preset duration t1, drop 4 is across first electrode A2 and the
Gap between one electrode A 3, and it is moved to the edge of first electrode A3, it keeps applying voltage to second electrode B2 at this time, simultaneously
Voltage is applied to first electrode A3；
S303, apply voltage to first electrode A3 after the first preset duration t2, stop applying electricity to second electrode B2
Pressure, drop 4 span the gap between second electrode B2 and second electrode B3 under the action of first electrode A3.
It should be noted that alive electrode is applied in the electrode representative of filled black in Fig. 9.Also, liquid is only shown in Fig. 7
The step of drop 4 is moved upwards up to first electrode A3 along movement routine side, subsequent move along movement routine does not show that.
It is corresponding with driving method shown in Fig. 9 that alive timing diagram such as Figure 10 institute is applied to first electrode and second electrode
Show, successively to second electrode B2, first electrode A3, second electrode B3 ..., first electrode An, second electrode Bn apply electricity
Pressure starts to apply next electrode voltage, and removes first and apply after applying two preset duration t1 of voltage regulation to each electrode
It is powered on outside the voltage of pole, stops applying voltage to a upper electrode after applying one preset duration t2 of voltage regulation to each electrode.
It specifically can use the first driving circuit and the second driving circuit respectively to carry out first electrode, second electrode
Driving.For example, first film transistor and first electrode correspond, the grid of first film transistor and the first scan line electricity
Connection, the source electrode of first film transistor are electrically connected with the first data line, the drain electrode of first film transistor and first electrode electricity
Connection, the second thin film transistor (TFT) and second electrode correspond, and the grid of the second thin film transistor (TFT) is electrically connected with the second scan line,
The source electrode of second thin film transistor (TFT) is electrically connected with the second data line, and the drain electrode of the second thin film transistor (TFT) is electrically connected with second electrode.
When determining the corresponding first electrode row of movement routine and second electrode row using droplet position detection unit, or determine the first electricity
Pole column and second electrode column, provide voltage signal for the first electrode and the second electrode, specifically include: to first electrode
The corresponding each first film transistor of row and high level signal is provided to corresponding each second thin film transistor (TFT) of second electrode row,
Or corresponding each first film transistor is arranged to first electrode and corresponding each second thin film transistor (TFT) is arranged to second electrode
High level signal is provided, first film transistor is controlled and the second thin film transistor (TFT) is opened.In the specific implementation, driving first is thin
The driving signal that film transistor and the second thin film transistor (TFT) are opened can for example use ac square wave signal, for example, can make
It obtains in the total duration of the second preset duration t1 and the first preset duration t2, application frequency is 100Hz, voltage is 0V/50V square wave
Signal, and apply 50 square-wave signals in total duration, total duration is 0.5 second (s), i.e. t1+t2=0.5s.Wherein first it is default when
Long t2 is not less than 0.02s, i.e. the first preset duration t2 is at least a square-wave cycle.
A kind of microfluidic system provided by the embodiments of the present application, including above-mentioned microfluidic devices provided by the embodiments of the present application
Part.
In conclusion micro-fluidic device provided by the embodiments of the present application and its driving method, microfluidic system, due to opposite
And the first substrate and the second substrate set are provided with the mobile electrode of driving drop, and at least one arrangement side of electrode
Upwards, the gap between the first electrode of first substrate and the gap between the second electrode of the second substrate are not handed over mutually
It is folded, that is to say, that first electrode and second electrode are staggered, at least one orientation of electrode, second electrode it
Between gap have with first electrode it is overlapping, the gap between first electrode have with second electrode it is overlapping, in this way, when drop need across
When gap more between electrode, have overlapping electrode that can drive to drop with gap, so as to control drop across
More gap.
Obviously, those skilled in the art can carry out various modification and variations without departing from the essence of the application to the application
Mind and range.In this way, if these modifications and variations of the application belong to the range of the claim of this application and its equivalent technologies
Within, then the application is also intended to include these modifications and variations.
Claims (10)
1. a kind of micro-fluidic device, which is characterized in that the micro-fluidic device includes: first substrate and the second base that be opposite and setting
Plate；Drop accommodating space is constituted between the first substrate and the second substrate；The first substrate includes: array arrangement
First electrode, the second substrate include: the second electrode of array arrangement；In at least one orientation of the first electrode
On, the gap between gap and the second electrode between the first electrode is non-overlapping；The first electrode and described
Second electrode is configured as: applying voltage to the first electrode and the second electrode, to control drop in first base
It is moved between plate and the second substrate.
2. micro-fluidic device according to claim 1, which is characterized in that the first electrode is along first direction and second
Direction arrangement, the second electrode are arranged along first direction and second direction；In said first direction, the first electrode
Between gap and the second electrode between gap it is non-overlapping；And/or in this second direction, first electricity
The gap between gap and the second electrode between pole is non-overlapping.
3. micro-fluidic device according to claim 1, which is characterized in that the shape of the first electrode and the second electrode
Shape and size are identical.
4. micro-fluidic device according to claim 1, which is characterized in that the first electrode and the second electrode are block
Shape electrode.
5. micro-fluidic device according to claim 4, which is characterized in that the center of the first electrode falls into described second
In gap between electrode, and the center of the second electrode is fallen into the gap between the first electrode.
6. micro-fluidic device according to claim 1, which is characterized in that the first substrate further include: with described first
Electrode corresponds and the first driving circuit of electrical connection；The second substrate further include: corresponded with the second electrode
And the second driving circuit of electrical connection.
7. a kind of driving method of micro-fluidic devices described in any item according to claim 1~6, which is characterized in that the side
Method includes:
Determine the initial position and movement routine of drop；
It is determined according to the initial position and the movement routine and controls the drop mobile first electrode and second electrode, institute
It states first electrode and the second electrode provides voltage signal, prolong the movement routine movement to control drop.
8. the method according to the description of claim 7 is characterized in that according to described in the initial position and movement routine control
Drop mobile first electrode and second electrode, specifically include:
According to the movement routine, the corresponding first electrode row of the movement routine and second electrode row are determined, alternatively, according to
The movement routine determines the corresponding first electrode column of the movement routine and second electrode column；
Also, the first of driving drop movement is determined in position of the initial position towards moving direction one side edge according to drop
A electrode；
Voltage signal is provided for the first electrode and the second electrode, prolongs the movement routine movement, tool to control drop
Body includes:
Since first electrode, on the direction along the movement routine, described first is moved to according to the drop
The sequence of electrode and the second electrode successively alternately applies voltage to the first electrode and the second electrode.
9. according to the method described in claim 8, it is characterized in that, moving road along described since first electrode
On the direction of diameter, the sequence of the first electrode and the second electrode is moved to according to the drop, successively to described first
Electrode and the second electrode successively alternately apply voltage, specifically include:
When the edge of the drop is moved to any first electrode, to first electrode application voltage, and to described
First electrode apply one preset duration of voltage regulation while, stop to in the movement routine opposite direction with it is described first electricity
The extremely adjacent second electrode applies voltage；
Alternatively, the edge when the drop is moved to any second electrode, voltage is applied to the second electrode, and right
While the second electrode applies one preset duration of voltage regulation, stop to in the movement routine opposite direction with described the
The adjacent first electrode of two electrodes applies voltage.
10. a kind of microfluidic system, which is characterized in that including the described in any item micro-fluidic devices of claim 1~6.
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