CN110404187B - Method for generating ultrahigh sound pressure and ultrahigh sound pressure generating device - Google Patents

Method for generating ultrahigh sound pressure and ultrahigh sound pressure generating device Download PDF

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CN110404187B
CN110404187B CN201810404153.0A CN201810404153A CN110404187B CN 110404187 B CN110404187 B CN 110404187B CN 201810404153 A CN201810404153 A CN 201810404153A CN 110404187 B CN110404187 B CN 110404187B
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sound
cavitation
generating
ultrasonic waves
ultra
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CN110404187A (en
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王芷龙
赵纯亮
李三勇
宋丹
雷光荣
张明军
许贵华
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Chongqing Haifu Medical Technology Co ltd
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Chongqing Haifu Medical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0056Beam shaping elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0056Beam shaping elements
    • A61N2007/0069Reflectors

Abstract

The invention provides a method for generating ultrahigh sound pressure and an ultrahigh sound pressure generating device, belongs to the technical field of high-intensity focused ultrasound and high-energy physics, and can solve the problem that the ultrahigh sound pressure in the existing acoustic cavitation is difficult to control and cannot be effectively utilized. The method for generating ultra-high sound pressure of the present invention comprises: emitting focused ultrasonic waves through a sound emitting surface arranged in a sound transmission medium, wherein at least part of the ultrasonic waves are reflected by the sound emitting surface, and the emitted ultrasonic waves and the reflected ultrasonic waves form a focused standing wave sound field on the inner side of the sound emitting surface; cavitation is initiated in the focal region of the standing wave sound field, and the cavitation bubbles collapse to generate ultrahigh sound pressure.

Description

Method for generating ultrahigh sound pressure and ultrahigh sound pressure generating device
Technical Field
The invention belongs to the technical field of high-intensity focused ultrasound, and particularly relates to a method for generating ultrahigh sound pressure and an ultrahigh sound pressure generating device.
Background
After the ultrasonic wave is focused, a region with high energy concentration can be obtained, and the region is called a focal region. By utilizing the characteristic, China develops the technology into high-intensity focused ultrasound tumor treatment equipment firstly, and applies the technology to clinically developing treatment of benign and malignant tumors such as liver tumor, kidney tumor, bone tumor, uterine fibroid and the like, so that good effects are obtained in the aspects of treatment safety, effectiveness and economy, and a new micro-noninvasive treatment technology direction is gradually formed.
Conventional ultrasonic focusing methods, such as spherical shell focusing, lens focusing, mirror focusing, and phase-controlled focusing, are all traveling wave focusing methods. The highest sound pressure achieved by the traveling wave focusing mode is 107Pa magnitude (for continuous wave) 108Pa magnitude (for pulse wave), the minimum focal domain size is wavelength magnitude, and the focal energy is difficult to further improve, so that the effect of the energy of higher magnitude sound pressure on tumor treatment cannot be researched.
In the prior art, under a certain condition, cavitation bubbles can be formed by applying focused ultrasound to a rigid interface surface, and the pressure intensity of a bubble wall can be calculated to be 7.7 +/-1.6 GPa through the propagation process of shock waves emitted by collapse of the cavitation bubbles adhered to the rigid surface, which is obtained by high-speed shooting. Meanwhile, relevant research and theoretical calculation show that the sound pressure generated when the cavitation bubbles collapse can reach 109Of the order of Pa. However, the range of the cavitation bubbles formed on the rigid surface by focusing the traveling wave is difficult to be restricted, so that although the cavitation energy generates ultra-high sound pressure, the energy of the cavitation can still not be effectively utilized due to the uncontrollable cavitation range.
Disclosure of Invention
The present invention is directed to solving at least one of the problems of the prior art by providing a method capable of producing a product of 10 or more9Pa magnitude and controllable range.
The technical scheme adopted for solving the technical problem of the invention is a method for generating ultrahigh sound pressure, which comprises the following steps:
emitting focused ultrasonic waves through a sound emitting surface arranged in a sound transmission medium, wherein at least part of the ultrasonic waves are reflected by the sound emitting surface, and the emitted ultrasonic waves and the reflected ultrasonic waves form a focused standing wave sound field on the inner side of the sound emitting surface; cavitation is initiated in the focal region of the standing wave sound field, and the cavitation bubbles collapse to generate ultrahigh sound pressure.
Preferably, the step of emitting the focused ultrasonic wave through the sound emitting surface provided in the sound transmitting medium further includes: the static pressure of the sound-transmitting medium is pressurized to at least a predetermined threshold value.
Further preferably, the predetermined threshold is 8 MPa.
Further preferably, the step of emitting the focused ultrasonic wave through the sound emitting surface provided in the sound transmission medium specifically includes:
transmitting focused ultrasonic waves at a first frequency through a sound emitting surface arranged in a sound transmission medium;
and adjusting the frequency of the ultrasonic wave until the emitted ultrasonic wave and the reflected ultrasonic wave form a focused standing wave sound field on the inner side of the sound production surface.
Further preferably, the inducing cavitation in the focal domain region of the standing wave sound field specifically includes:
adjusting the intensity of the ultrasonic wave to induce cavitation within a focal domain region of the standing wave acoustic field.
Preferably, the ultra-high sound pressure generated when the cavitation bubbles collapse is 10 or more9Pa。
Preferably, the extent of cavitation induced in the focal zone is less than or equal to the wavelength of the ultrasound waves in any direction.
Preferably, the waveform of the ultrasonic wave is one of a continuous wave and a burst wave.
Preferably, the sound-transmitting medium comprises deionized, degassed water.
Preferably, the shape of the sound emitting surface is any one of a spherical surface, a cylindrical surface and a truncated spherical surface.
The technical scheme adopted for solving the technical problem of the invention is an ultrahigh sound pressure generating device, which comprises:
a sound-transmitting medium accommodating unit for accommodating a sound-transmitting medium;
a sound emitting unit provided in the sound-transmitting medium accommodating unit and having a sound emitting surface for emitting focused ultrasonic waves through the sound emitting surface, the sound emitting surface being capable of reflecting at least part of the ultrasonic waves so that the emitted ultrasonic waves and the reflected ultrasonic waves form a focused standing wave sound field on an inner side of the sound emitting surface and induce cavitation in a focal region of the standing wave sound field,
ultra-high sound pressure is generated by collapse of cavitation bubbles.
Preferably, the sound-transmitting medium accommodating unit is a hyperbaric chamber.
Preferably, the ultra-high sound pressure generating apparatus further includes: a pressurizing unit for pressurizing the static pressure of the sound-transmitting medium to at least a predetermined threshold value.
In the method for generating ultrahigh sound pressure, a standing wave sound field is formed by utilizing the emission and reflection of ultrasonic waves, and cavitation is automatically initiated in a focal region of the standing wave sound field, so that 10 can be formed9Pa magnitude of ultra-high sound pressure, and meanwhile, the cavitation range is limited within the focal domain range by utilizing the acoustic tweezers action of the standing wave sound field, so that the cavitation range is effectively controlled, and the ultra-high sound pressure generated by cavitation is effectively utilized.
Drawings
Fig. 1 is a flowchart of an ultra-high sound pressure generating method according to an embodiment of the present invention;
fig. 2 is a schematic view of the ultra-high sound pressure generating method according to an embodiment of the present invention;
FIG. 3 is a schematic illustration of the propagation of ultrasonic waves in an embodiment of the present invention;
fig. 4 is a schematic structural view of an ultra-high sound pressure generating apparatus according to an embodiment of the present invention;
wherein the reference numerals are: 1. a sound-transmitting medium accommodating unit; 2. a pressure gauge; 5. an aerial insertion flange plate; 6. a cable compression-resistant adapter; 8. a high power supply; 9. a pressure boosting device; 10. a water purification device; 11. an electromagnetic valve; 13. a water inlet interface; 14. a water drainage interface; 15. installing a base; 16. opening the door quickly; 18. an ultrasound transducer.
Detailed Description
In order to make the technical solutions of the present invention better understood, the present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
Example 1:
as shown in fig. 1 to 3, the present embodiment provides a method for generating ultra-high sound pressure, which can be used for an ultrasonic transducer to generate ultra-high sound pressure (for example, greater than or equal to 10)9Sound pressure of the order of Pa).
The method for generating ultra-high sound pressure comprises the following steps:
emitting focused ultrasonic waves through a sound emitting surface arranged in a sound transmission medium; forming a focused standing wave sound field on the inner side of the sound generating surface through the reflection of at least part of the ultrasonic wave by the sound generating surface; cavitation is initiated in the focal region of the standing wave sound field, and the cavitation bubbles collapse to generate ultrahigh sound pressure.
The 'cavitation is initiated in the focal domain range of the standing wave sound field, and the cavitation bubbles collapse to generate ultrahigh sound pressure' means that under the static pressure of a certain sound transmission medium, by controlling the characteristic parameters of the frequency, the power and the like of the emitted ultrasonic wave, the cavitation only occurs in the focal domain range of the standing wave sound field in the sound production plane and is restricted in the region, so that the control of the cavitation range is realized, and the control of the range of the ultrahigh sound pressure generated by the collapse of the cavitation bubbles is further realized.
The above method may be implemented by an ultrasonic transducer, that is, the ultrasonic wave may be generated by the ultrasonic transducer, and the present embodiment will be described below by taking the example of generating ultra-high sound pressure by the ultrasonic transducer.
The ultrasonic transducer comprises a shell, wherein a sound generating unit (such as a high-power driving power supply) is arranged on the outer surface of the shell and can generate ultrasonic waves. The inner surface of the shell can be used as the sound production surface (ultrasonic wave emission surface) and has the function of reflecting ultrasonic waves, so that a resonant cavity is formed inside the shell. The housing is filled with an acoustic medium having a static pressure, preferably the acoustic medium may comprise deionized degassed water to ensure cavitation energy levels while maintaining ultrasonic transmission. Wherein, the deionized and deaerated water can be provided by a water purifying device.
The ultrasonic wave that the sound production unit sent can pierce through ultrasonic transducer's casing, sends from the internal surface of casing to transmit in the casing with the help of the sound-transmitting medium, can take place to reflect when meeting the sound production face, and finally, the ultrasonic wave that the sound production unit sent and the ultrasonic wave after the reflection form the standing wave sound field in casing inside, and focus in the regional focus and form the high sound pressure region of subwavelength. In this embodiment, the intensity of the emitted ultrasonic wave is enough to autonomously initiate cavitation in the focal region, so that the acoustic medium forms a cavitation bubble group in the focal region. Under the action of alternating ultrasonic waves, the cavitation bubble groups slowly expand downwards under negative pressure and are rapidly contracted and collapsed downwards under positive pressure, so that a high-temperature and high-pressure environment can be formed in a focal region by virtue of the cavitation action. In addition, in the embodiment, due to the action of the acoustic tweezers in the standing wave sound field, cavitation bubble groups generated by cavitation can be clamped, so that the cavitation bubble groups are always located in the focal region range, the cavitation range is effectively controlled, the ultra-high sound pressure generated by cavitation is effectively utilized, and the ultra-high sound pressure with a controllable range is achieved.
Specifically, as shown in fig. 1 and 2, the method for generating ultra-high sound pressure in the present embodiment may include:
s0, preferably, the static pressure of the sound-transmitting medium is pressurized by a pressurizing means to at least a predetermined threshold value.
In the embodiment, the standing wave sound field is utilized to generate cavitation in the focal region, and the cavitation threshold and the range size of the cavitation region are related to the environmental pressure (the static pressure of the sound transmission medium). The increase in static pressure suppresses the occurrence of cavitation, increases the cavitation threshold, and in this case, requires a higher intensity of ultrasonic waves to ensure the occurrence of cavitation, so in this case, the intensity of generated cavitation is also higher, that is, the magnitude of ultra-high sound pressure formed by the collapse of the final cavitation bubbles is also higher. At the same time, the extent of the cavitation zone decreases exponentially as the static pressure of the sound-transmitting medium increases. That is to say, through promoting the static pressure of sound-transmitting medium, can compress the cavitation bubble of high strength in the less within range in the focus area to can realize the super high sound pressure of small-range, improve the precision of the production scope of super high sound pressure, further realize the accurate control to super high sound pressure production scope. Meanwhile, since the static pressure of the sound-transmitting medium is related to the cavitation threshold, if the ultrasonic wave is transmitted first and then the static pressure is adjusted, parameters such as the transmission frequency and intensity of the ultrasonic wave may need to be adjusted again. Therefore, in this embodiment, it is preferable to pressurize the static pressure of the sound-transmitting medium to a predetermined threshold value or more and then emit ultrasonic waves, so as to simplify the operation steps.
Among them, it is preferable that the predetermined threshold value of the static pressure of the sound-transmitting medium is 8 MPa. That is, the static pressure of the sound-transmitting medium is preferably increased to 8MPa or more. The existing experimental data show that when the static pressure reaches 8MPa, the range of the cavitation region can be reduced to half wavelength order, and the formed ultrahigh sound pressure can reach 109Pa magnitude, far greater than 10 that can be formed in the prior art8Of the order of Pa.
S1, emitting the focused ultrasonic wave at the first frequency through the sound emitting surface provided in the sound transmitting medium.
The first frequency may be any frequency. That is to say, when sound generating unit began to pass through the sound surface transmission ultrasonic wave, do not do special concrete restriction to the power and the frequency of ultrasonic wave, although the ultrasonic wave of transmission also can be reflected by the sound surface this moment, can not certainly form the standing wave sound field in the emergence face.
It will of course be appreciated that the sound-transmitting medium should have a certain static pressure. If the above-described pressurizing step (S0) is included, the sound-transmitting medium at this time should have the above-described static pressure after being pressurized, which reaches the predetermined threshold value.
And S2, adjusting the frequency of the ultrasonic wave until a focused standing wave sound field is formed on the inner side of the sound emitting surface through the reflection of at least part of the ultrasonic wave by the sound emitting surface.
After the ultrasonic wave is started to be emitted, the frequency of the ultrasonic wave is gradually adjusted until a focused standing wave sound field can be formed in the sound production surface through reflection. In the present embodiment, it is preferable to select an ultrasonic wave of a resonance frequency depending on the size of the sound emitting surface as the excitation ultrasonic wave (emitted ultrasonic wave).
In the present embodiment, the waveform of the ultrasonic wave may be any waveform, and for example, may be a continuous wave or a burst wave. When the waveform of the ultrasonic wave is a pulse train wave, the duty ratio can be any duty ratio.
And S3, adjusting the intensity of the ultrasonic wave until cavitation is initiated in the focal domain area of the standing wave sound field.
When the ultrasonic wave forms a standing wave sound field in the sound emitting surface, the intensity of the ultrasonic wave is not necessarily enough to induce cavitation in the focal region of the standing wave sound field due to the static pressure of the sound transmitting medium and the limit of the frequency of the ultrasonic wave on the cavitation threshold. Therefore, in the present embodiment, it is possible to ensure that cavitation is autonomously induced in the focal region of the standing wave sound field by adjusting the intensity of the ultrasonic wave (for example, increasing the intensity of the ultrasonic wave). Of course, when the ultrasonic wave is emitted, the ultrasonic wave with high power can also be directly emitted, so that the intensity of the ultrasonic wave is enough to initiate cavitation, and the adjustment step is simplified.
Furthermore, after the cavitation is initiated, the intensity of the ultrasonic wave can be continuously adjusted subsequently, so that the intensity of the cavitation is changed, and then ultrahigh sound pressure with different sizes is generated at the focal region position of the standing wave sound field. Specifically, in the present embodiment, the intensity of the ultrasonic wave can be adjusted by adjusting the electric power of the sound generating unit (for example, the output power of the high-power driving power supply), so as to adjust the intensity of the cavitation.
Preferably, in practical applications, the emission maintaining time of the ultrasonic wave can be controlled according to requirements, so as to control the time for generating cavitation in the focal region, that is, the duration of the ultra-high sound pressure. Specifically, in this embodiment, the duration of the ultra-high sound pressure may be controlled by controlling the operating time of the generating unit.
In this embodiment, the shape of the sound emission surface is preferably any one of a spherical surface, a cylindrical surface, and a truncated spherical surface. That is, the shape of the housing of the ultrasonic transducer may be a spherical shell shape, a cylindrical shape, or a truncated spherical shell shape, and the focal region position is located at the spherical center position (or the center position of the cylindrical shape). The shell of the truncated spherical shell shape should include a center position (the center of the sphere is located within the truncated sphere). In particular, the housing may be shaped as a table of a sphere, for example a drum. In practical application, the shape can be other shapes, and the shapes are not listed. For example, as shown in fig. 3, when the housing of the ultrasonic transducer is spherical, the ultrasonic waves emitted by the sound emitting unit penetrate through the housing of the ultrasonic transducer, propagate to the center of sphere position O through the inner surface of the housing of the ultrasonic transducer, continue to propagate to the inner surface of the housing of the ultrasonic transducer after passing through the center of sphere position O, and then form reflected waves through reflection of the inner surface of the housing of the ultrasonic transducer. When the ultrasonic transducer shell and the ultrasonic wave meet the resonance condition, namely the inner surface of the ultrasonic transducer shell forms a resonant cavity, the phase of the ultrasonic wave directly focused at the spherical center position O is the same as that of the reflected wave, so that the sound wave coherence superposition can be formed at the spherical center position O, a stable spherical standing wave sound field with high intensity is formed in the resonant cavity, and the spherical center position O reaches high sound pressure, so that the sound pressure of a focal region is improved, and further cavitation is initiated. Meanwhile, the sphere center O is positioned at the center of the spherical standing wave sound field, and the centers of all directions of acoustic radiation force are symmetrical, so that the cavitation bubble group is clamped at the sphere center (focal region).
In the method for generating ultra-high sound pressure provided by this embodiment, a standing wave sound field is formed by the emission and reflection of ultrasonic waves, and cavitation is autonomously induced in a focal region of the standing wave sound field, so that a pressure of 10 or more can be formed9Pa magnitude of ultra-high sound pressure, and meanwhile, the cavitation range is limited within the focal domain range by utilizing the acoustic tweezers action of the standing wave sound field, so that the cavitation range is effectively controlled, and the ultra-high sound pressure generated by cavitation is effectively utilized. In this embodiment, the size of the static pressure, the intensity of the ultrasonic wave, and the duration are controlled to further control the space (range), intensity, and duration of the cavitation.
Example 2:
as shown in fig. 4, the present embodiment provides an ultra-high sound pressure generating apparatus which can form high sound pressure according to the method of generating ultra-high sound pressure provided in embodiment 1. The ultra-high sound pressure generating device includes: a sound-transmitting medium housing unit 1 for housing a sound-transmitting medium; and a sound generating unit provided in the sound-transmitting medium accommodating unit 1 and having a sound generating surface. The sounding unit is used for emitting focused ultrasonic waves through the sounding surface; reflecting at least a portion of the ultrasonic waves such that the emitted ultrasonic waves and the reflected ultrasonic waves form a focused standing wave sound field within the sound emanating surface; and cavitation can be triggered in a focal domain region of a standing wave sound field, and ultrahigh sound pressure is generated by collapse of cavitation bubbles.
That is, in the ultra-high sound pressure generating apparatus of the present embodiment, the sound generating surface of the sound generating unit can emit and reflect the ultrasonic wave, and the material, the size, the range (including the characteristics of frequency, intensity, and the like) of the sound generating unit that can emit the ultrasonic wave, and the like are limited, so that the ultrasonic wave can be finally ensured to form a standing wave sound field in the sound generating surface, and cavitation can be generated, thereby generating the ultra-high sound pressure by collapse of the cavitation bubbles.
Specifically, the sound emitting surface may be an inner surface of a housing of the ultrasonic transducer 18, and the shape of the sound emitting surface may be any one of a spherical surface, a cylindrical surface, and a truncated spherical surface, that is, the housing of the ultrasonic transducer 18 may be spherical shell shaped, cylindrical, or truncated spherical shell shaped, and the focal region position is located at a spherical center position (or a center position of the cylinder). The shell of the truncated spherical shell shape should include a center position (the center of the sphere is located within the truncated sphere).
The sound generating unit may be a device capable of generating ultrasonic waves, such as piezoelectric ceramics or 1-3 type piezoelectric composite materials, disposed on the outer surface of the housing of the ultrasonic transducer 18.
The sound-transmitting medium containing unit 1 may be a hyperbaric chamber, and may contain a sound-transmitting medium having a relatively high static pressure therein. The ultrasonic transducer 18 can be placed in the hyperbaric chamber through the quick opening door 16 and placed on the mounting base 15, and the sound generating unit is connected to the high power supply 8 through the cable pressure resistant adaptor 6 mounted on the aerial flange 5. Meanwhile, the inside of the housing of the ultrasonic transducer 18 is communicated with the inside of the hyperbaric chamber, so that the inside of the housing can be filled with sound-transmitting media with higher static pressure. Among them, preferably, the sound-transmitting medium may be deionized deaerated water.
In this embodiment, the ultrasonic waves emitted by the sound emitting unit (not shown in the figure) can penetrate through the shell of the ultrasonic transducer 18, are emitted from the inner surface of the shell, and are transmitted in the shell by means of the sound transmission medium, and are reflected when meeting the sound emitting surface, and finally, the ultrasonic waves emitted by the sound emitting unit and the reflected ultrasonic waves form a standing wave sound field in the shell and are focused in the focal region. The intensity of the ultrasonic wave emitted in the embodiment is enough to autonomously initiate cavitation in the focal region, so that the sound-transmitting medium forms cavitation bubble groups in the focal region, and under the action of the alternating ultrasonic wave, the cavitation bubble groups slowly expand downwards under negative pressure and rapidly contract and collapse downwards under positive pressure, so that a high-temperature and high-pressure environment can be formed in the focal region; in addition, in the embodiment, due to the action of the acoustic tweezers in the standing wave sound field, cavitation bubble groups generated by cavitation can be clamped, so that the cavitation bubble groups are always located in the focal region range, the cavitation range is effectively controlled, the ultra-high sound pressure generated by cavitation is effectively utilized, and the ultra-high sound pressure with a controllable range is generated in the focal region.
Preferably, the ultra-high sound pressure generating apparatus further comprises: and the water purifying device 10 can be connected with a water inlet interface 13 of the high-pressure cabin through a water inlet pipeline and provides deionized and degassed water for the high-pressure cabin to serve as a sound transmission medium.
Preferably, the ultra-high sound pressure generating apparatus further comprises a pressurizing unit 9 for pressurizing the static pressure of the sound-transmitting medium to at least a predetermined threshold value. The cavitation threshold and the extent of the cavitation zone are related to the ambient pressure (static pressure of the acoustic medium). The increase in static pressure inhibits the occurrence of cavitation, raising the cavitation threshold, in which case higher intensity ultrasound is required to ensure cavitation, so in this case the intensity of the cavitation produced is also greater, i.e. the magnitude of the ultra-high sound pressure that can ultimately be formed is also higher. At the same time, the extent of the cavitation zone decreases exponentially as the static pressure of the sound-transmitting medium increases. That is, by raising the static pressure of the sound-transmitting medium, the high-intensity cavitation can be limited to a small range, for example, the range of cavitation induced in the focal region can be limited to the wavelength range of the ultrasonic wave (that is, the size of the cavitation range in any direction is smaller than or equal to the wavelength of the ultrasonic wave), so that the ultra-high sound pressure in a small range can be realized, and the accuracy of the generation range of the ultrasonic sound pressure can be improved.
Specifically, a water inlet pipe of the pressurizing unit 9 is connected with a pressurizing water tank in the water purifying device 10, a high-pressure water outlet is connected with the high-pressure chamber through an electromagnetic valve 11, water is injected into the high-pressure chamber for pressurizing through control software of the pressurizing unit 9, and when hydrostatic pressure in the high-pressure chamber is increased to a set hydrostatic value (namely, a preset threshold value), water feeding of the pressurizing unit 9 is stopped through feedback of a pressure sensor. Wherein the pressurizing unit 9 further comprises a pressure gauge 2 for displaying the current static pressure value. Wherein, in the initial stage of pressurization, the exhaust valve of the hyperbaric chamber can be opened to exhaust the gas in the chamber body, and then the exhaust valve is closed.
The ultra-high sound pressure generating device provided in this embodiment forms a standing wave sound field in the housing of the ultrasonic transducer 18 by using ultrasonic waves, and autonomously induces cavitation in a focal region of the standing wave sound field, thereby forming a sound pressure of 10 or more9Pa magnitude of ultra-high sound pressure, and meanwhile, the cavitation range is limited within the focal domain range by utilizing the acoustic tweezers action of the standing wave sound field, so that the cavitation range is effectively controlled, and the ultra-high sound pressure generated by cavitation is effectively utilized. In this embodiment, the size of the static pressure, the intensity of the ultrasonic wave, and the duration of the ultrasonic wave are controlled to further control the space, intensity, and duration of the cavitation.
It will be understood that the above embodiments are merely exemplary embodiments taken to illustrate the principles of the present invention, which is not limited thereto. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit and substance of the invention, and these modifications and improvements are also considered to be within the scope of the invention.

Claims (10)

1. A method of generating ultra-high sound pressure, comprising:
emitting focused ultrasonic waves through a sound emitting surface arranged in a sound transmission medium, wherein the sound emitting surface reflects at least part of the ultrasonic waves, the emitted ultrasonic waves and the reflected ultrasonic waves form a focused standing wave sound field on the inner side of the sound emitting surface, and cavitation is initiated in a focal region of the focused standing wave sound field, and the cavitation bubbles collapse to generate ultrahigh sound pressure;
the step of emitting focused ultrasonic waves through a sound emitting surface arranged in the sound transmission medium further comprises the following steps of: pressurising the static pressure of the sound-transmitting medium to at least a predetermined threshold value;
the sound-transmitting medium comprises deionized, degassed water.
2. The method of generating ultra-high acoustic pressure according to claim 1,
the predetermined threshold is 8 MPa.
3. The method for generating ultra-high acoustic pressure according to claim 1, wherein the step of emitting focused ultrasonic waves through a sound emitting surface provided in the sound-transmitting medium specifically comprises:
transmitting focused ultrasonic waves at a first frequency through a sound emitting surface arranged in a sound transmission medium;
and adjusting the frequency of the ultrasonic wave until the emitted ultrasonic wave and the reflected ultrasonic wave form a focused standing wave sound field on the inner side of the sound production surface.
4. The method for generating ultra-high acoustic pressure according to claim 3, wherein the inducing cavitation within the focal domain region of the standing wave acoustic field specifically comprises:
adjusting the intensity of the ultrasonic wave to induce cavitation within a focal domain region of the standing wave acoustic field.
5. The method of generating ultra-high acoustic pressure according to claim 1,
the ultra-high sound pressure generated when the cavitation bubbles collapse is greater than or equal to 109Pa。
6. The method of generating ultra-high acoustic pressure according to claim 1,
the extent of cavitation induced in the focal zone is less than or equal to the wavelength of the ultrasound waves in any direction.
7. The method of generating ultra-high acoustic pressure according to claim 1,
the waveform of the ultrasonic wave is one of a continuous wave and a pulse train wave.
8. The method of generating ultra-high acoustic pressure according to claim 1,
the shape of the sounding surface is any one of a spherical surface, a cylindrical surface and a truncated spherical surface.
9. An ultra-high sound pressure generating apparatus, comprising:
a sound-transmitting medium accommodating unit for accommodating a sound-transmitting medium;
a sound generating unit provided in the sound-transmitting medium accommodating unit and having a sound generating surface for emitting focused ultrasonic waves through the sound generating surface, the sound generating surface being capable of reflecting at least a part of the ultrasonic waves so that the emitted ultrasonic waves and the reflected ultrasonic waves form a focused standing wave sound field on the inner side of the sound generating surface and induce cavitation in the focal region of the formed standing wave sound field to generate ultra-high sound pressure by collapse of cavitation bubbles;
a pressurizing unit for pressurizing a static pressure of the sound-transmitting medium to at least a predetermined threshold value;
the sound-transmitting medium comprises deionized, degassed water.
10. The ultra-high sound pressure generating apparatus as claimed in claim 9,
the sound-transmitting medium containing unit is a high-pressure cabin.
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