CN110376392B - Method and device for scheduling waste reaction cups, analytical instrument and storage medium - Google Patents
Method and device for scheduling waste reaction cups, analytical instrument and storage medium Download PDFInfo
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- CN110376392B CN110376392B CN201910616000.7A CN201910616000A CN110376392B CN 110376392 B CN110376392 B CN 110376392B CN 201910616000 A CN201910616000 A CN 201910616000A CN 110376392 B CN110376392 B CN 110376392B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/0092—Scheduling
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
Abstract
The invention discloses a waste reaction cup dispatching method and device, an analysis instrument and a storage medium. The method for scheduling the waste reaction cup comprises the following steps: determining the treatment time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage; in response to the arrival of the processing timing, sending a discarding instruction for the discarded cuvette to a discarded cuvette processing section of the analysis instrument to perform a waste liquid extraction operation for the discarded cuvette and discard the discarded cuvette into a first waste basket; the target flow is one of actual working flows of the analysis instrument, and the actual working flows comprise at least one of the following flows: testing normal flow, testing abnormal flow, maintaining normal flow and maintaining abnormal flow. By adopting the technical scheme provided by the embodiment of the invention, the scheduling flow of the waste reaction cup can be simplified on the premise of avoiding pollution of the waste reaction cup.
Description
Technical Field
The invention relates to the technical field of reaction analysis equipment, in particular to a waste reaction cup scheduling method and device, an analysis instrument and a storage medium.
Background
During testing and maintenance, the analytical instrument generates a large number of waste reaction cups, and the reaction cups need to be treated to avoid pollution or other losses due to possible residual samples and reagents in the reaction cups. The existing reaction cup scheduling mode mainly includes that waste reaction cups which are subjected to normal testing/maintenance are discarded into a waste storage bucket after waste liquid treatment is carried out on the waste reaction cups through a detection bin, and the waste reaction cups which are required to be discarded due to abnormality in the testing/maintenance process are discarded at different outlets generally, and waste liquid treatment is not carried out on the waste reaction cups, so that pollution is caused, and the scheduling flow of the waste reaction cups is complicated.
Disclosure of Invention
The embodiment of the invention provides a method and a device for dispatching waste reaction cups, an analysis instrument and a storage medium, which can simplify the dispatching flow of the waste reaction cups on the premise of avoiding pollution of the waste reaction cups.
In a first aspect, an embodiment of the present invention provides a method for scheduling a waste reaction cup, which is used for an analytical instrument, and the method for scheduling a waste reaction cup includes: determining the treatment time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage; in response to the arrival of the treatment time, sending a discarding instruction of the waste reaction cup to a detection bin of the analysis instrument so as to perform waste liquid extraction operation on the waste reaction cup and discard the waste reaction cup into a first waste material barrel; the target flow is one of actual working flows of the analysis instrument, and the actual working flows comprise at least one of the following flows: testing normal flow, testing abnormal flow, maintaining normal flow and maintaining abnormal flow.
In a possible implementation manner of the first aspect, the step of determining the processing time of the waste reaction cup according to the generating stage and the target flow corresponding to the generating stage includes: if the waste reaction cup is generated in the detection completion stage of the normal flow of the test, the treatment time is after the detection is completed.
In a possible implementation manner of the first aspect, the step of determining the processing time of the waste reaction cup according to the generating stage and the target flow corresponding to the generating stage includes: if the abandoned reaction cup is generated in the manual shutdown stage or the fault shutdown stage of the abnormal testing process, the treatment time is the reaction cup cleaning step of a new round of testing process after the analysis instrument is reset or the reaction cup cleaning step of a new round of maintenance process.
In a possible implementation manner of the first aspect, the step of determining the processing time of the waste reaction cup according to the generating stage and the target flow corresponding to the generating stage includes: if the abandoned reaction cup is generated in a non-stop operation failure stage or an operation delay stage of the abnormal testing process, the processing time is the idle time of a gripper in the subsequent process of the abnormal testing process; and if the grippers are in the non-idle state continuously in the subsequent flow, the processing time is delayed until the whole non-stop test abnormal flow is ended.
In a possible implementation manner of the first aspect, the step of determining the processing time of the waste reaction cup according to the generating stage and the target flow corresponding to the generating stage includes: if the abandoned reaction cup is generated in the maintenance completion stage of the normal maintenance flow, the treatment time is after the maintenance is completed; if the abandoned reaction cup is generated in the maintenance failure shutdown stage of the maintenance abnormal flow, the treatment time is the reaction cup removing step of the new round of test flow after the analysis instrument is reset or the reaction cup removing step of the new round of maintenance flow.
In a possible implementation of the first aspect, the actual workflow further comprises a dilution flow; the step of determining the processing time of the waste reaction cup according to the generation stage and the target flow corresponding to the generation stage comprises the following steps: if the waste reaction cup is generated in the sampling completion stage of the dilution flow, the processing time is the idle time of the gripper after the dilution flow is finished.
In a possible implementation manner of the first aspect, the method for scheduling the discarded reaction cups further includes: in response to detecting that a discard cuvette is discarded into the first waste vat, the number of valid cuvettes in the database is updated.
In a possible implementation manner of the first aspect, the disposal cuvette handling section is a detection chamber of an analysis instrument.
In a second aspect, an embodiment of the present invention provides a waste cuvette scheduler, including: the processing time determining module is used for determining the processing time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage; the discarding instruction sending module is used for sending a discarding instruction of the waste reaction cup to a waste reaction cup processing part of the analysis instrument in response to the arrival of the processing time so as to perform waste liquid extraction operation on the waste reaction cup and discard the waste reaction cup into a first waste material barrel; the target flow is one of actual working flows of the analysis instrument, and the actual working flows comprise at least one of the following flows: testing normal flow, testing abnormal flow, maintaining normal flow and maintaining abnormal flow.
In a third aspect, embodiments of the present invention provide an analytical instrument comprising: a cuvette scheduler as described above; and the waste reaction cup treatment part is used for receiving the discarding instruction sent by the waste reaction cup dispatching device, performing waste liquid extraction operation on the waste reaction cup and discarding the waste reaction cup into the first waste material barrel.
In a fourth aspect, embodiments of the present invention provide a storage medium having a program stored thereon, which when executed by a processor implements a method of scheduling waste cuvettes as described above.
As described above, the method for scheduling the waste reaction cups in the embodiment of the invention establishes a unified scheduling flow for the waste reaction cups in different states or generated in different flows: firstly, determining the treatment time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage; and then, in response to the arrival of the processing time, sending a discarding instruction of the discarded reaction cups to a discarded reaction cup processing part of the analysis instrument so as to uniformly perform waste liquid extraction operation on the discarded reaction cups and discard the discarded reaction cups into a first waste barrel.
Compared with the prior art that waste reaction cups which are subjected to normal testing/maintenance are required to be discarded into a waste bucket after being subjected to waste liquid treatment by a detection bin, and the waste reaction cups which are required to be discarded due to abnormality in the testing/maintenance process are discarded at different outlets, and the waste reaction cups are not subjected to waste liquid treatment, the embodiment of the invention can uniformly schedule the waste reaction cups which are in different states or are generated in different processes (including the waste reaction cups which are required to be discarded due to abnormality in the testing/maintenance process after the normal testing/maintenance process) and uniformly extract waste liquid from the waste reaction cups by a waste reaction cup treatment part and discard the waste reaction cups into a first waste bucket, so that the scheduling process of the waste reaction cups can be simplified on the premise of avoiding pollution of the waste reaction cups.
Drawings
The invention will be better understood from the following description of specific embodiments thereof taken in conjunction with the accompanying drawings, in which like or similar reference characters designate like or similar features.
FIG. 1 is a schematic view showing the structure of components related to cuvette transfer in an analytical instrument according to an embodiment of the present invention;
FIG. 2 is a flow chart of a method for scheduling waste reaction cups according to an embodiment of the present invention;
FIG. 3 is a flow chart of a method for scheduling waste reaction cups according to another embodiment of the present invention;
FIG. 4 is a flow chart of a method for scheduling waste reaction cups according to another embodiment of the present invention;
fig. 5 is a schematic structural diagram of a waste reaction cup dispatching device according to an embodiment of the present invention.
Detailed Description
Features and exemplary embodiments of various aspects of the invention are described in detail below. In the following detailed description, numerous specific details are set forth in order to provide a thorough understanding of the invention.
The embodiment of the invention provides a waste reaction cup dispatching method and device, an analysis instrument and a storage medium. By adopting the technical scheme provided by the embodiment of the invention, the scheduling flow of the waste reaction cup can be simplified on the premise of avoiding pollution of the waste reaction cup.
Fig. 1 is a schematic structural diagram of a component related to cuvette transfer in an analysis apparatus according to an embodiment of the present invention, where a represents a cuvette loading bin, B represents a cuvette loading tray, C represents a cuvette loading tray, D represents a cleaning station, E represents a detection bin, and F represents a gripper. The waste bin is located below the detection bin (not shown).
In the normal flow of the test, the transfer of the reaction cup comprises the following steps:
(1) The reaction cup is loaded from the reaction cup loading bin A to the reaction cup loading disc B to wait.
(2) The gripper F grabs the reaction cup from the reaction cup loading disc B to the reaction bin C for a first-step reaction.
(3) After the reaction is completed, the gripper F grips the reaction cup to the cleaning station D for cleaning.
(4) If the reaction needs to be continued, the gripper F grips the reaction cup to the reaction bin C for continuous reaction, and the step (3) is executed.
(5) If all reactions are completed, the gripper F grips the reaction cup from the cleaning station D to the detection bin E for detection.
(6) After detection, the reaction cup is subjected to waste liquid extraction treatment, and the reaction cup is discarded into a waste barrel through holes in the detection bin E.
Besides the test flow, the transfer of the reaction cup may be involved in the maintenance process, that is, after the reaction cup is grasped to a maintenance position by a gripper for maintenance according to the maintenance requirement, the reaction cup is grasped to a detection bin for processing.
In the testing and maintenance process, the analyzer generates a large number of waste reaction cups, and the reaction cups need to be treated to avoid pollution or other losses due to possible residual samples and reagents in the reaction cups.
The method for scheduling the waste reaction cups in the embodiment of the invention aims to uniformly process all the waste reaction cups (including the waste reaction cups which are required to be subjected to the testing/maintenance process normally and the waste reaction cups which are generated due to abnormality in the testing/maintenance process) in the waste reaction cup processing part, and comprises the steps of extracting waste liquid from the waste reaction cups and discarding the waste reaction cups into a first waste barrel, so that the scheduling flow of the waste reaction cups is simplified on the premise of avoiding pollution caused by the waste reaction cups, and the reaction cups are convenient to count.
Fig. 2 is a flow chart of a method for dispatching a waste cuvette according to an embodiment of the invention, which is used in the above-mentioned analysis apparatus, and the method for dispatching a waste cuvette includes steps 201 to 202.
In step 201, the timing of processing the waste cuvette is determined based on the generation stage of the waste cuvette and the target flow corresponding to the generation stage.
The target process corresponding to the generation stage of the waste reaction cup is one of actual working processes of the analysis instrument, and the actual working processes comprise at least one of the following processes: testing normal flow, testing abnormal flow, maintaining normal flow and maintaining abnormal flow.
For a normal flow of test, the cuvette may be identified as a waste cuvette after the test is completed.
For a test anomaly procedure, the reaction cup in the retention instrument after the test is stopped abnormally in the middle of the test can be identified as a waste reaction cup. Failure in the middle of the test (for example, mixing failure of the reaction cups) or delayed reaction cups (for example, a plurality of reaction cups need to be grasped from the detection bin at the same time, but a hand grip can grasp only one reaction cup at a time, and reaction timeout occurs when the reaction cup is not grasped), and the like, and the abnormal reaction cup can be identified because of invalid test results.
For the maintenance normal flow, the reaction cup can be identified as a waste reaction cup after the maintenance is completed. The maintenance types mainly include: the method comprises the steps of (1) weekly maintenance, (2) monthly maintenance, (3) test end maintenance, (4) startup maintenance, (5) shutdown maintenance, (6) pipeline filling, (7) pipeline cleaning, (8) substrate filling, (9) instrument resetting, (10) magnetic bead uniform mixing, (11) cleaning of a reaction cup, (12) reagent scanning, and (13) soaking and needle washing. Wherein, (1) - (5) are compound maintenance items, including a plurality of maintenance items, all comprising the step of cleaning the reaction cup; (6) - (12) is a single maintenance item, and the step of cleaning the cuvette must be performed before performing (6), (7), (13).
For maintenance abnormal flows, failure of maintenance will lead to instrument downtime, after which the reaction cups in the retained instrument can be identified as waste reaction cups.
In some embodiments, the target flow further may include a dilution flow.
The one-step dilution flow is as follows: firstly, sampling a reaction cup Y1, adding a diluent into the reaction cup Y1 to dilute to a set multiple, and sampling the sample from the reaction cup Y1 as a sample to be reacted. In the one-step dilution flow, after all sampling of the reaction cup Y1 is completed, the reaction cup Y1 becomes a waste reaction cup;
the two-step dilution flow is as follows: firstly sampling to dilute the reaction cup Y1 to a certain multiple, sampling from the reaction cup Y1 to the reaction cup Y2, continuously diluting to the set multiple, enabling the reaction cup Y1 to be a waste reaction cup, then sampling from the reaction cup Y2 to serve as a sample to be reacted, and enabling the reaction cup Y2 to be a waste reaction cup after sampling.
In step 202, in response to the arrival of the processing timing, a discard instruction for the discard cuvette is sent to the discard cuvette processing section of the analysis instrument to perform a waste liquid extraction operation for the discard cuvette and discard the discard cuvette into the first waste basket.
The waste reaction cups generated in the testing/maintaining processes are uniformly extracted by the waste reaction cup processing part, and the waste reaction cups are uniformly discarded into a single waste barrel (namely, a first waste barrel).
According to different instrument designs, the disposal part of the disposal reaction cup can be an independent disposal part specially arranged for the disposal reaction cup, or can be an existing part in an analysis instrument: and (5) detecting a bin. If the waste reaction cup is directly treated by the detection bin, a new treatment component does not need to be additionally arranged, so that the improvement of the existing analysis instrument is avoided, and the effect of saving the cost can be achieved. Further, if the waste reaction cup is treated by the detection bin, the first waste bin may be located below the detection bin.
As described above, the method for scheduling the waste reaction cups in the embodiment of the invention establishes a unified scheduling flow for the waste reaction cups in different states or generated in different flows: firstly, determining the treatment time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage; and then, in response to the arrival of the processing time, sending a discarding instruction of the discarded reaction cups to a discarded reaction cup processing part of the analysis instrument so as to uniformly perform waste liquid extraction operation on the discarded reaction cups and discard the discarded reaction cups into a first waste barrel.
Compared with the prior art that waste reaction cups which are subjected to normal testing/maintenance are required to be discarded into a waste bucket after being subjected to waste liquid treatment by a detection bin, and the waste reaction cups which are required to be discarded due to abnormality in the testing/maintenance process are discarded at different outlets, and the waste reaction cups are not subjected to waste liquid treatment, the embodiment of the invention can uniformly schedule the waste reaction cups which are in different states or are generated in different processes (including the waste reaction cups which are required to be discarded due to abnormality in the testing/maintenance process after the normal testing/maintenance process) and uniformly extract waste liquid from the waste reaction cups by a waste reaction cup treatment part and discard the waste reaction cups into a first waste bucket, so that the scheduling process of the waste reaction cups can be simplified on the premise of avoiding pollution of the waste reaction cups.
In addition, according to the embodiment of the invention, since all the waste reaction cups need to be transferred to the waste reaction cup processing part for unified processing, the action of transferring the waste reaction cups to the waste reaction cup processing part can be executed by the same gripper for the waste reaction cups in different processes, so that the structure of an instrument and the scheduling process of the gripper can be simplified.
In some embodiments, in response to detecting that a waste cuvette is discarded into a first waste receptacle, the number of valid cuvettes in the database may be updated, thereby avoiding counting errors due to discarding of waste cuvettes into different waste receptacles, and improving accuracy of cuvette counting. In the specific implementation, after the reaction cup is loaded in the reaction cup loading bin, the related information such as batch numbers, quantity and the like of the reaction cups can be registered in a user software interface. When the waste reaction cup processing part detects that the waste reaction cup enters the waste material barrel through the waste reaction cup processing part in a discarding mode through the photoelectric detector, the number of the reaction cups is correspondingly updated in the database, and meanwhile, the number of the reaction cups on the user software interface is refreshed.
The processing timing of the waste reaction cup according to the different target flows will be specifically described below.
Fig. 3 is a flow chart of a method for scheduling waste reaction cups according to another embodiment of the present invention. Fig. 3 differs from fig. 1 in that step 201 in fig. 1 may be thinned into steps 2011 to 2016 in fig. 3.
In step 2011, if the discarded reaction cup is generated at the detection completion stage of the normal flow, the processing timing is after the detection is completed.
In the step, if the waste reaction cup is generated in the detection completion stage of the normal flow, the waste reaction cup can be extracted for waste liquid treatment after the detection is completed according to the normal flow.
In step 2012, if the discarded cuvette is generated in the manual shutdown phase or the failure shutdown phase of the abnormal testing process, the processing time is the cuvette cleaning step of the new testing process after the analysis instrument is reset, or the cuvette cleaning step of the new maintenance process.
In the step, if the abandoned reaction cup is generated in the manual shutdown stage or the fault shutdown stage of the abnormal flow, the shutdown processing countermeasure of the abnormal flow is tested according to the steps: the instrument needs to be reset and retested/serviced. At this time, if a test is selected, the instrument automatically performs pre-test maintenance, including cleaning the reaction cup; if maintenance is directly selected, the instrument judges whether maintenance of cleaning the reaction cup is required to be carried out firstly according to the selected maintenance types (1) - (13), if the selected maintenance type is (6), (7) or (13), the step of cleaning the reaction cup is carried out firstly, and if the selected maintenance type is other, the step of cleaning the reaction cup is to be carried out, and when the step of cleaning the reaction cup is to be carried out, the waste reaction cup is transferred to a detection bin to extract waste liquid and then is thrown into a first waste material barrel. Therefore, the processing time of the step can be the step of cleaning the reaction cup of a new round of test flow after the analysis instrument is reset or the step of cleaning the reaction cup of a new round of maintenance flow. By the arrangement, the processing time of the waste reaction cup can be integrated with the step of clearing the reaction cup in the inherent program, and the waste reaction cup is processed while the step of clearing the reaction cup is carried out, so that the scheduling step and the time slice are not required to be added specially for the processing of the waste reaction cup, and the scheduling efficiency of the waste reaction cup can be improved on the premise of avoiding influencing the existing scheduling flow.
In step 2013, if the discarded reaction cup is generated in the non-stop operation failure stage or the non-stop operation delay stage of the abnormal testing process, the processing time is the idle time of the gripper in the subsequent process of the abnormal testing process.
In this step, if the discarded reaction cups fail in the non-stop operation of the abnormal flow (for example, mixing of the reaction cups fails) or the non-stop operation is delayed (for example, a plurality of reaction cups need to be grasped from the detection bin at the same time, but the hand grip can grasp only one reaction cup at a time, and the reaction cup which is not grasped has a reaction timeout) and the like, although the test result is invalid, the test is continued according to the original flow without stopping, and at this time, the processing time can be the idle time of the hand grip in the subsequent flow of the abnormal flow. In the step, the waste reaction cups are processed at the idle moment of the grippers, the scheduling step and the time slice allocation are not required to be added specially for the processing of the waste reaction cups, and the scheduling efficiency of the waste reaction cups can be improved on the premise of avoiding influencing the existing scheduling flow.
In the subsequent process of discarding the reaction cup, the actions required to be executed by the gripper generally include: the method comprises the steps of (1) grabbing a reaction disc from a cleaning station, (2) grabbing a detection bin from the cleaning station, (3) grabbing the reaction disc from the reaction disc to the cleaning station, (4) grabbing the reaction disc from a reaction cup loading disc, (5) grabbing the reaction disc from an inner disc of the reaction disc to an outer disc of the reaction disc, and (6) grabbing the reaction disc to the detection bin. The priority of (1) and (2) is highest, and then (3), (4), (5) and (6) are sequentially carried out, and when no other flow is used for scheduling the grippers, the grippers are considered to be idle.
In some embodiments, if the gripper is continuously in the non-idle state in the subsequent process, the processing time may be extended until the entire non-stop test abnormal process ends.
In step 2014, if the waste reaction cup is generated in the normal maintenance process, the processing timing is after the maintenance is completed.
In the step, if the waste reaction cup is generated in the maintenance normal flow, the waste reaction cup can be extracted for waste liquid treatment after the maintenance is completed according to the maintenance normal flow.
In step 2015, if the discarded reaction cup is generated at the maintenance completion stage of the maintenance abnormal flow, the processing time is the reaction cup cleaning step of the new round of test flow after the analysis instrument is reset, or the reaction cup cleaning step of the new round of maintenance flow.
In the step, if the abandoned reaction cup is generated in the maintenance failure shutdown stage of the maintenance abnormal flow, the shutdown processing countermeasure of the maintenance abnormal flow is taken as follows: the instrument needs to be reset and retested/serviced. At this time, if a test is selected, the instrument automatically performs pre-test maintenance, including cleaning the reaction cup; if maintenance is directly selected, the instrument judges whether maintenance of the reaction cup cleaning needs to be performed firstly according to the selected maintenance types (1) - (13), if the selected maintenance type is (6), (7) or (13), the reaction cup cleaning step is performed firstly, and if the selected maintenance type is other, the waste reaction cup is transferred to the detection bin to extract waste liquid and then is thrown into the first waste material bucket when the reaction cup cleaning step is to be performed, so that the treatment time of the step can be the reaction cup cleaning step of a new round of test flow after the analysis instrument is reset or the reaction cup cleaning step of a new round of maintenance flow. The step can integrate the treatment time of the waste reaction cup with the step of clearing the reaction cup in the inherent program, and the treatment of the waste reaction cup is realized while the step of clearing the reaction cup, so that the scheduling step and the time slice are not required to be added specially for the treatment of the waste reaction cup, and the scheduling efficiency of the waste reaction cup can be improved on the premise of avoiding influencing the existing scheduling flow.
In step 2016, if the discard cup is generated at the sampling completion stage of the dilution flow, the processing timing is the hand-free time after the end of the dilution flow.
For example, a sample taken after dilution of cuvette Y1 in a one-step dilution (as a sample to be reacted) indicates that cuvette Y1 is sampled. In the two-step dilution, sampling from the diluted cuvette Y1 to the cuvette Y2 indicates that sampling of the cuvette Y1 is completed, and sampling from the diluted cuvette Y2 (as a sample to be reacted) indicates that sampling of the cuvette Y2 is completed. The sample to be reacted after the dilution is finished is required to be subjected to reaction disk reaction, cleaning by a cleaning station and detection by a detection station, and the reaction disk reaction, the cleaning station and the detection station are all required to be cooperatively implemented by the grippers, so that the idle time of the grippers after the dilution flow is finished can be used as the processing time of the step in order to avoid interference with the subsequent flow or to insert new tasks into the grippers.
Fig. 4 is a flow chart of a method for scheduling waste reaction cups according to another embodiment of the present invention, which is used for illustrating a specific implementation of the method for scheduling waste reaction cups. As shown in fig. 4, the method for scheduling the waste reaction cups includes steps 401 to 405.
In step 401, it is determined whether or not there is a waste cuvette. If not, step 402 is executed, otherwise, the processing is divided according to the target flow generated by the discarding reaction.
In step 402, a test normal flow is performed until the detection is completed, and step 403 is performed.
In step 403, the waste cuvette detection chamber is used to extract waste liquid from the waste cuvette.
In step 404, the discarded cuvette is discarded to a first waste vat.
Specifically, the case-division processing flow in step 401 includes:
(1) If the discard cup is generated in the maintenance flow, step 405 is performed.
In step 405, it is determined whether the apparatus is stopped, if yes, step 406 is performed, otherwise, step 403 is performed after maintenance is completed.
In step 406, the instrument is reset and then tested/maintained.
(2) If the discard cup is generated in the test flow, step 405 is performed.
In step 405, it is determined whether the instrument is stopped, if yes, step 406 is performed, otherwise, step 403 is performed when the gripper is idle.
(3) If the waste cup is generated in the dilution process, step 403 is executed when the standby gripper is idle.
Fig. 5 is a schematic structural diagram of a waste reaction cup dispatching device according to an embodiment of the present invention. As shown in fig. 5, the waste cuvette scheduler 500 includes: a processing timing determination module 501 and a discard instruction transmission module 502.
The processing timing determining module 501 is configured to determine a processing timing of the waste reaction cup according to a generation stage of the waste reaction cup and a target flow corresponding to the generation stage.
The discarding instruction sending module 502 is configured to send, in response to the arrival of the processing opportunity, a discarding instruction for the waste cuvette to a detection bin of the analysis instrument, so as to perform a waste liquid extraction operation on the waste cuvette and discard the waste cuvette into the first waste basket.
The target flow is one of actual working flows of the analysis instrument, and the actual working flows comprise at least one of the following flows: the waste reaction cup dispatching device 500 in the embodiment of the invention establishes a unified dispatching flow for waste reaction cups in different states or generated in different flows: the processing time determining module 501 determines the processing time of the waste reaction cup according to the generation stage of the waste reaction cup and the target flow corresponding to the generation stage; then, the discard instruction transmission module 502 transmits a discard instruction for the discard cuvette to the discard cuvette processing section of the analysis apparatus in response to the arrival of the processing timing so as to uniformly perform the waste liquid extraction operation for the discard cuvette and discard the discard cuvette into the first waste basket.
Compared with the prior art that waste reaction cups which are subjected to normal testing/maintenance are required to be discarded into a waste bucket after being subjected to waste liquid treatment by a detection bin, and the waste reaction cups which are required to be discarded due to abnormality in the testing/maintenance process are discarded at different outlets, and the waste reaction cups are not subjected to waste liquid treatment, the waste reaction cup scheduling device 500 in the embodiment of the invention can uniformly schedule the waste reaction cups which are in different states or are generated in different processes (including the waste reaction cups which are required to be discarded after the testing/maintenance process and the waste reaction cups which are generated due to abnormality in the testing/maintenance process) and uniformly extract the waste liquid from the waste reaction cups by the waste reaction cup treatment part and discard the waste reaction cups into the first waste bucket, so that the scheduling process of the waste reaction cups can be simplified on the premise of avoiding pollution.
The embodiment of the invention also provides an analysis instrument, which comprises: the waste cuvette scheduler and the waste cuvette handling section as described above. The specific implementation form of the waste reaction cup dispatching device can be a processing device with a single logic operation function, or can be a main controller in an analysis instrument, and is not limited herein. The waste reaction cup processing part is used for receiving a discarding instruction sent by the reaction cup dispatching device, performing waste liquid extraction operation on the waste reaction cup and discarding the waste reaction cup into the first waste material barrel. The disposal cup treatment section may be a detection chamber or may be an independent treatment member provided specifically for the disposal cup, depending on the design of the apparatus, and is not limited herein.
The embodiment of the invention also provides a storage medium, wherein a program is stored on the storage medium, and when the program is executed by a processor, the waste reaction cup scheduling method is realized.
It should be understood that, in the present specification, each embodiment is described in an incremental manner, and the same or similar parts between the embodiments are all referred to each other, and each embodiment is mainly described in a different point from other embodiments. For device embodiments, reference may be made to the description of method embodiments for relevant points. The embodiments of the invention are not limited to the specific steps and structures described above and shown in the drawings. Those skilled in the art will appreciate that various alterations, modifications, and additions may be made, or the order of steps may be altered, after appreciating the spirit of the embodiments of the present invention. Also, a detailed description of known method techniques is omitted here for the sake of brevity.
The functional blocks shown in the above-described structural block diagrams may be implemented in hardware, software, firmware, or a combination thereof. When implemented in hardware, it may be, for example, an electronic circuit, an Application Specific Integrated Circuit (ASIC), suitable firmware, a plug-in, a function card, or the like. When implemented in software, the elements of an embodiment of the invention are the programs or code segments used to perform the required tasks. The program or code segments may be stored in a machine readable medium or transmitted over transmission media or communication links by a data signal carried in a carrier wave. A "machine-readable medium" may include any medium that can store or transfer information. Examples of machine-readable media include electronic circuitry, semiconductor memory devices, ROM, flash memory, erasable ROM (EROM), floppy disks, CD-ROMs, optical disks, hard disks, fiber optic media, radio Frequency (RF) links, and the like. The code segments may be downloaded via computer networks such as the internet, intranets, etc.
Embodiments of the invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. For example, the algorithms described in particular embodiments may be modified without departing from the basic spirit of embodiments of the invention. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of embodiments of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Claims (10)
1. A method of scheduling waste reaction cups for use in an analytical instrument, comprising:
determining the treatment time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage;
transmitting a discarding instruction for the waste cuvette to a waste cuvette handling section of an analyzer in response to the arrival of the handling timing, so as to perform a waste liquid extraction operation for the waste cuvette and discard the waste cuvette into a first waste basket;
wherein the target flow is one of actual workflows of the analytical instrument, the actual workflow including at least one of the following flows: testing a normal flow, testing an abnormal flow, maintaining the normal flow and maintaining the abnormal flow;
the step of determining the processing time of the waste reaction cup according to the generation stage and the target flow corresponding to the generation stage comprises the following steps:
if the waste reaction cup is generated in the maintenance completion stage of the normal maintenance flow, the treatment time is after the maintenance is completed;
if the abandoned reaction cup is generated in the maintenance failure shutdown stage of the maintenance abnormal flow, the processing time is the reaction cup removing step of a new round of test flow after the analysis instrument is reset or the reaction cup removing step of a new round of maintenance flow.
2. The method of claim 1, wherein the step of determining the timing of the processing of the waste reaction cup based on the generation phase and a target flow corresponding to the generation phase comprises:
if the waste reaction cup is generated in the detection completion stage of the normal flow of the test, the treatment time is after the detection is completed.
3. The method of claim 1, wherein the step of determining the timing of the processing of the waste reaction cup based on the generation phase and a target flow corresponding to the generation phase comprises:
if the abandoned reaction cup is generated in the manual shutdown stage or the fault shutdown stage of the abnormal testing process, the processing time is the reaction cup cleaning step of a new round of testing process or the reaction cup cleaning step of a new round of maintenance process after the analysis instrument is reset.
4. The method of claim 1, wherein the step of determining the timing of the processing of the waste reaction cup based on the generation phase and a target flow corresponding to the generation phase comprises:
if the abandoned reaction cup is generated in a non-stop operation failure stage or an operation delay stage of the abnormal testing process, the processing time is the idle time of a gripper in the subsequent process of the abnormal testing process;
and if the grippers are in a non-idle state continuously in the subsequent process, the processing time is delayed until the whole abnormal test process is finished.
5. The method of claim 1, wherein the step of determining the position of the substrate comprises,
the actual workflow further includes a dilution flow;
the step of determining the processing time of the waste reaction cup according to the generation stage and the target flow corresponding to the generation stage comprises the following steps:
and if the waste reaction cup is generated in the sampling completion stage of the dilution flow, the processing time is the idle time of the gripper after the dilution flow is finished.
6. The method according to any one of claims 1-5, further comprising:
in response to detecting that the discarded cuvette is discarded into the first waste vat, the number of valid cuvettes in the database is updated.
7. The method of any one of claims 1-5, wherein the waste cuvette handling section is a detection bin of the analytical instrument.
8. A waste cuvette scheduler, comprising:
the processing time determining module is used for determining the processing time of the waste reaction cup according to the generation stage of the waste reaction cup and a target flow corresponding to the generation stage;
a discarding instruction sending module, configured to send a discarding instruction for the waste cuvette to a waste cuvette processing section of an analysis instrument in response to the arrival of the processing timing, so as to perform a waste liquid extraction operation on the waste cuvette and discard the waste cuvette into a first waste bucket;
wherein the target flow is one of actual workflows of the analytical instrument, the actual workflow including at least one of the following flows: testing a normal flow, testing an abnormal flow, maintaining the normal flow and maintaining the abnormal flow;
the processing time determining module is specifically configured to:
if the waste reaction cup is generated in the maintenance completion stage of the normal maintenance flow, the treatment time is after the maintenance is completed;
if the abandoned reaction cup is generated in the maintenance failure shutdown stage of the maintenance abnormal flow, the processing time is the reaction cup removing step of a new round of test flow after the analysis instrument is reset or the reaction cup removing step of a new round of maintenance flow.
9. An analytical instrument, comprising:
the discard reaction cup dispenser of claim 8;
and the waste reaction cup treatment part is used for receiving the discarding instruction sent by the waste reaction cup dispatching device, performing waste liquid extraction operation on the waste reaction cup and discarding the waste reaction cup into the first waste material barrel.
10. A storage medium having a program stored thereon, wherein the program when executed by a processor implements the method of scheduling waste cuvettes according to any one of claims 1 to 7.
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