CN110376299A - The measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper - Google Patents
The measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper Download PDFInfo
- Publication number
- CN110376299A CN110376299A CN201910548459.8A CN201910548459A CN110376299A CN 110376299 A CN110376299 A CN 110376299A CN 201910548459 A CN201910548459 A CN 201910548459A CN 110376299 A CN110376299 A CN 110376299A
- Authority
- CN
- China
- Prior art keywords
- migration
- solution
- naphthalene
- diisopropyl naphthalene
- silicone oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8624—Detection of slopes or peaks; baseline correction
- G01N30/8631—Peaks
- G01N30/8634—Peak quality criteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N2030/042—Standards
- G01N2030/045—Standards internal
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N2030/062—Preparation extracting sample from raw material
Abstract
The present invention relates to the measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper, include the following steps: to configure diisopropyl naphthalene standard reserving solution, diethyl naphthalene internal standard stock solution, standards of alcohol working solution, oil base standard working solution；6dm2The silicone oil paper sample contact 1kg food simulants of area carry out migration test, and the simulated solution after pipetting migration is added sodium chloride and ethyl acetate, internal standard stock solution, ultrasonic extraction, supernatant liquid is taken to analyze for GC-MS in tool plug centrifuge tube；Ion detection is selected, inner mark method ration obtains the amount of migration of diisopropyl naphthalene.The present invention optimizes detection pre-treatment process, coded program, the selection of GC-MS chromatographic column and temperature program, substantially reduces the detection time of diisopropyl naphthalene the amount of migration, promotes working efficiency, while reducing detection limit.This method is simple and efficient, with excellent sensitivity and stability, meets analysis detection and accurate quantitative analysis to diisopropyl naphthalene the amount of migration in silicone oil paper.
Description
Technical field
The invention belongs to technical field of food safety detection, and in particular to diisopropyl naphthalene the amount of migration in a kind of silicone oil paper
Measuring method.
Background technique
Silicone oil paper is a kind of wrapping paper, it is ubiquitous in life, has three-layer structure.First layer structure is base stock,
Second layer structure is lamination, and third layer structure is silicone oil.Silicone oil paper has the characteristics that high temperature resistant, moisture-proof, grease proofing, therefore general more
It is packed for food service industry.Silicone oil paper is tough, anti-extrusion, folding are rubbed, and can play the role of protecting commodity in packing article.?
The silicone oil paper frequently encountered in daily life mainly has barbecue paper, roast duck wrapping paper and packaging bag of some food etc..
Diisopropyl naphthalene (DIPN) has outstanding advantages of colourless, tasteless, strong to dyestuff solvability, is widely used in paper
Etc..Foreign study found that diisopropyl naphthalene is easy to cause to hurt to human body from moving in paper in dry food
Evil.It is domestic at present less to diisopropyl naphthalene migration quantifier elimination report in silicone oil paper, have to the examination criteria of diisopropyl naphthalene
Solvent extraction measures diisopropyl naphthalene (DIPN) content in EU criteria BS EN 14719:2005 paper pulp, paper and cardboard,
The professional standard of China's entry and exit is using gas chromatography-mass spectrography (GC-MS) to food contact material paper and cardboard diisopropyl
Naphthalene (DIPN) measurement.But it is relatively fewer for the measurement of the amount of migration.
Summary of the invention
The present invention overcomes deficiency in the prior art, it is to provide a kind of survey of diisopropyl naphthalene the amount of migration in silicone oil paper
Determine method, this method is simple and efficient, with excellent sensitivity and stability.
The specific technical solution of the present invention is as follows:
The measuring method of diisopropyl naphthalene the amount of migration, includes the following steps: in silicone oil paper
Configure diisopropyl naphthalene standard reserving solution；
Configure diethyl naphthalene internal standard stock solution；
Configure standards of alcohol working solution；
Configure oil base standard working solution；
Sample pretreatment: area-method is used, 6dm is taken2The silicone oil paper sample of area, 6dm2The silicone oil paper sample of area contacts
1kg food simulants, 40-100 DEG C at a temperature of carry out the migration test of 2-5h, simulated solution after being migrated；
Simulated solution after pipetting migration is in tool plug centrifuge tube, addition sodium chloride and ethyl acetate into centrifuge tube, then plus
Enter diethyl naphthalene internal standard stock solution, ultrasonic extraction takes supernatant liquid to analyze for GC-MS；
Ion detection is selected, inner mark method ration obtains the amount of migration of diisopropyl naphthalene in silicone oil paper sample.
Preferably, when supernatant is analyzed using GC-MS, chromatographic condition are as follows: chromatographic column (DB-5MS 30m ×
0.25mm×0.25μm)；Temperature program: 70 DEG C of holding 2min rise to 250 DEG C with 10 DEG C/min rate, keep 10min；Carrier gas:
High-pure helium, purity >=99.999%；Input mode: Splitless injecting samples, 250 DEG C；Ionization mode: electronic and ionic source；Ionization
Voltage: 70eV；Makings interface temperature: 300 DEG C.
Preferably, the food simulants are 50% ethyl alcohol, isooctane.
Preferably, it configures diisopropyl naphthalene standard reserving solution: weighing 30mg diisopropyl naphthalene standard items in 25ml volumetric flask
In, scale is diluted to dehydrated alcohol.
Preferably, it configures diethyl naphthalene internal standard stock solution: weighing 50mg diethyl naphthalene standard items in 25ml volumetric flask, use
Dehydrated alcohol is diluted to scale.
Preferably, it configures standards of alcohol working solution: measuring 0.1ml, 0.2ml, 0.5ml, 1.0ml, 2.0ml bis- respectively
Dehydrated alcohol is added extremely in 5 25ml volumetric flasks in the diethyl naphthalene internal standard stock solution of isopropyl naphthalene standard reserving solution and 100ul
Scale is spare.
Preferably, it configures oil base standard working solution: measuring 0.1ml, 0.2ml, 0.5ml, 1.0ml, 2.0ml bis- respectively
Isooctane is added to quarter in 5 25ml volumetric flasks in the diethyl naphthalene internal standard stock solution of isopropyl naphthalene standard reserving solution and 100ul
It spends spare.
Preferably, the simulated solution after pipetting 5.00mL migration has in plug centrifuge tube in 50mL, is separately added into centrifuge tube
0.5g sodium chloride and 5mL ethyl acetate, add 20uL diethyl naphthalene internal standard stock solution, and ultrasonic extraction 15min takes supernatant
Liquid is analyzed for GC-MS.
Detection pre-treatment process and coded program is optimized in the present invention, the selection and liter by GC-MS chromatographic column
The optimization of warm program substantially reduces the detection time of diisopropyl naphthalene the amount of migration, promotes working efficiency, while reducing detection
Limit.This method is simple and efficient, with excellent sensitivity and stability, meets and migrates to diisopropyl naphthalene in silicone oil paper (DIPN)
The analysis detection and accurate quantitative analysis of amount.
Detailed description of the invention
Fig. 1 is diisopropyl naphthalene the amount of migration (μ g/L) and migrates the relationship (isooctane) of temperature.
Specific embodiment
Further illustrate that the present invention, the present invention do not refer to that part is the prior art with reference to embodiments.
Instrument and equipment
Agilent 7890A gas chromatograph: Agilent company, the U.S..
Agilent 5975C gas chromatograph-mass spectrometer: Agilent company, the U.S..
Milli-Q ultrapure water instrument: Millipore company, the U.S..
N-EVP-12 nitrogen concentrating instrument: the U.S..
KQ300DB ultrasonic cleaner: Kunshan Ultrasonic Instruments Co., Ltd..
RE-5299 type Rotary Evaporators: Shanghai Yarong Biochemical Instrument Plant.
Reagent
Ethyl acetate: HPLC grades, Sigma Co., USA.
Dehydrated alcohol: HPLC grades, German Merck company.
Isooctane: HPLC grades, German Merck company.
Diisopropyl naphthalene (DIPN) standard items: purity >=97.0% (mass fraction), Town in Shanghai compose company.
Diethyl naphthalene standard items: internal standard compound, purity >=97.0% (mass fraction), Town in Shanghai compose company.
Sample pretreatment of the present invention is referring to " GB 31604.1-2015 national food safety standard food contacts material
Material and product migration test general rule ".
Migrate influence of the temperature to object the amount of migration
According to the difference of silicone oil paper packaged food type, selects isooctane to carry out migration experiment as food simulants, move
It moves experimental temperature and selects 0-100 DEG C, transit time is 2h.By taking DIPN in sample as an example, temperature is migrated to object the amount of migration
Influence it is as shown in Figure 1.The result shows that effect is best under 40-100 DEG C of transition condition and is not much different by DIPN, it is preferred that move
Moving temperature is 40 DEG C.
Effect of extracting of the different simulated solutions to different substrates
When choosing n-hexane, methylene chloride, acetonitrile, 50% ethyl alcohol and isooctane as analogies respectively, to the extraction of DIPN
Take capability result as shown in table 1, the results showed that, DIPN can migrate two different matrix in 5 kinds of simulated solutions, wherein
50% ethyl alcohol and isooctane migration effect in corresponding matrix are best, and the migration effect of methylene chloride, acetonitrile, ethyl acetate
Generally, therefore the present invention chooses 50% ethyl alcohol and isooctane and carries out as simulated solution.
Effect of extracting of the different simulated solutions of table 1 to different substrates
The influence of transit time
Reference sample pre-treatment step, using the rate of recovery as index, respectively investigate extraction time 40min, 80min,
The influence (being shown in Table 2) of 120min, 160min and 300min to migration effect, the results showed that, transit time 40min, the rate of recovery exists
53.5%-66.8%；Transit time 80min, the rate of recovery is in 79.86%-82.77%；Transit time 120min, recycling
Rate is in 93.69%-95.88%, and transit time is more than 120min, and the rate of recovery is not significantly increased, therefore transit time selects
120-300min, preferred transit time are 120min (2h).
Influence of 2 transit time of table to the DIPN rate of recovery
Linear relationship and precision
Diisopropyl naphthalene standard reserving solution is taken, a certain amount of internal standard solution is added, dilutes step by step respectively, draws standard curve, is made
Linear regression analysis (referring to conventional method in the art).DIPN 0.1-100 mg/kg sample introduction concentration range in two kinds of matrix
Interior corresponding peak area is in a linear relationship, and related coefficient is all larger than 0.995, obtains the range of linearity of each substance, regression equation,
The RSD of peak area when related coefficient and 2 kinds of target substance concentrations are 10 μ g/L is shown in Table 3.
3 DIPN of table in two kinds of matrix the range of linearity, regression equation, related coefficient (r) and peak area RSD
The rate of recovery, detection limit and quantitative limit
Detection limit (LOD) and quantitative limit (LOQ) are determined respectively according to 3 times and 10 times of signal-to-noise ratio (S/N), in negative sample base
0.5,5.0,50.0,200.0mg/L 4 horizontal mixed standard solutions are added in matter, are located in advance by sample pretreatment step
Reason, each horizontal replication 6 times obtain the average recovery of standard addition of DIPN, detection limit and quantitative limit (being shown in Table 4).Detection limit
For 0.5mg/kg, it is quantitatively limited to 1.0mg/kg；And the average recovery of standard addition of DIPN is in the case where 4 various concentration mark-ons are horizontal
82.0%-95.34% can satisfy the detection demand of diisopropyl naphthalene in silicone oil paper (DIPN).
Average recovery of standard addition, RSD, detection limit and the quantitative limit of different substrates DIPN in 4 silicone oil paper of table
Embodiment
The measuring method of diisopropyl naphthalene the amount of migration, includes the following steps: in silicone oil paper
Configuration diisopropyl naphthalene standard reserving solution: 30mg diisopropyl naphthalene standard items are weighed in 25ml volumetric flask, with nothing
Water-ethanol is diluted to scale.
Configuration diethyl naphthalene internal standard stock solution: 50mg diethyl naphthalene standard items are weighed in 25ml volumetric flask, with anhydrous second
Alcohol is diluted to scale.
It configures standards of alcohol working solution: measuring 0.1ml, 0.2ml, 0.5ml, 1.0ml, 2.0ml diisopropyl naphthalene respectively
It is standby to scale that dehydrated alcohol is added in 5 25ml volumetric flasks in the diethyl naphthalene internal standard stock solution of standard reserving solution and 100ul
With.
It configures oil base standard working solution: measuring 0.1ml, 0.2ml, 0.5ml, 1.0ml, 2.0ml diisopropyl naphthalene respectively
It is spare to scale that isooctane is added in 5 25ml volumetric flasks in the diethyl naphthalene internal standard stock solution of standard reserving solution and 100ul.
Sample pretreatment: area-method is used, 6dm is taken2The silicone oil paper sample of area, select 50% ethyl alcohol, isooctane as
Food simulants, 6dm2The silicone oil paper sample of area contacts 1kg food simulants, 40 DEG C at a temperature of carry out the migration examination of 2h
It tests, the simulated solution after being migrated；
Simulated solution after pipetting 5.00mL migration has in plug centrifuge tube in 50mL, and 0.5g chlorine is separately added into centrifuge tube
Change sodium and 5mL ethyl acetate, adds 20uL diethyl naphthalene internal standard stock solution, ultrasonic extraction 15min takes supernatant liquid to be used for
GC-MS analysis.
Chromatographic condition are as follows: chromatographic column (30m × 0.25mm × 0.25 μm DB-5MS)；Temperature program: 70 DEG C of holding 2min,
250 DEG C are risen to 10 DEG C/min rate, keeps 10min；Carrier gas: high-pure helium, purity >=99.999%；Input mode: it does not shunt
Sample introduction, 250 DEG C；Ionization mode: electronic and ionic source；Ionizing voltage: 70eV；Makings interface temperature: 300 DEG C.Each compound
Mass spectrum acquisition parameter is shown in Table 5.
Each compound mass spectrometry parameters condition of table 5
Ion detection is selected, inner mark method ration obtains the amount of migration of diisopropyl naphthalene in silicone oil paper sample.
The present invention establishes gas chromatography-mass spectrography (GC-MS) measurement of diisopropyl naphthalene in silicone oil paper (DIPN).Two
The range of linearity of isopropyl naphthalene (DIPN) the amount of migration is 0.1-100mg/kg；Detection is limited to 0.5mg/kg；Quantitative limit is (with signal-to-noise ratio
>=10 meters) it is 1.0mg/kg；In the case where 3 mark-ons are horizontal, average recovery of standard addition is 82.0%-95.34%, relative standard deviation
For 2.08%-3.95% (n=6).This method is simple and efficient, with excellent sensitivity and stability, meets in silicone oil paper
The analysis detection and accurate quantitative analysis of diisopropyl naphthalene (DIPN) the amount of migration.
Claims (8)
1. the measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper, it is characterised in that include the following steps:
Configure diisopropyl naphthalene standard reserving solution；
Configure diethyl naphthalene internal standard stock solution；
Configure standards of alcohol working solution；
Configure oil base standard working solution；
Sample pretreatment: area-method is used, 6dm is taken2The silicone oil paper sample of area, 6dm2The silicone oil paper sample contact 1kg food of area
Product analogies, 40-100 DEG C at a temperature of carry out the migration test of 2-5h, simulated solution after being migrated；
Sodium chloride and ethyl acetate are added into centrifuge tube, adds two in tool plug centrifuge tube for simulated solution after pipetting migration
Ethylnaphthalene internal standard stock solution, ultrasonic extraction take supernatant liquid to analyze for GC-MS；
Ion detection is selected, inner mark method ration obtains the amount of migration of diisopropyl naphthalene in silicone oil paper sample.
2. measuring method according to claim 1, which is characterized in that when supernatant is analyzed using GC-MS, chromatostrip
Part are as follows: chromatographic column (DB-5MS30m × 0.25mm × 0.25 μm)；Temperature program: 70 DEG C of holding 2min, with 10 DEG C/min rate liter
To 250 DEG C, 10min is kept；Carrier gas: high-pure helium, purity >=99.999%；Input mode: Splitless injecting samples, 250 DEG C；Ionization
Mode: electronic and ionic source；Ionizing voltage: 70eV；Makings interface temperature: 300 DEG C.
3. measuring method according to claim 2, which is characterized in that the food simulants are 50% ethyl alcohol, isooctane.
4. measuring method according to claim 1 or 2 or 3, which is characterized in that configuration diisopropyl naphthalene standard reserving solution:
30mg diisopropyl naphthalene standard items are weighed in 25ml volumetric flask, are diluted to scale with dehydrated alcohol.
5. measuring method according to claim 4, which is characterized in that configuration diethyl naphthalene internal standard stock solution: weigh 50mg
Diethyl naphthalene standard items are diluted to scale in 25ml volumetric flask, with dehydrated alcohol.
6. measuring method according to claim 5, which is characterized in that configuration standards of alcohol working solution: measure respectively
The diethyl naphthalene internal standard stock solution of 0.1ml, 0.2ml, 0.5ml, 1.0ml, 2.0ml diisopropyl naphthalene standard reserving solution and 100ul
In 5 25ml volumetric flasks, it is spare to scale that dehydrated alcohol is added.
7. measuring method according to claim 6, which is characterized in that configuration oil base standard working solution: measure respectively
The diethyl naphthalene internal standard stock solution of 0.1ml, 0.2ml, 0.5ml, 1.0ml, 2.0ml diisopropyl naphthalene standard reserving solution and 100ul
In 5 25ml volumetric flasks, it is spare to scale that isooctane is added.
8. measuring method according to claim 7, which is characterized in that the simulated solution after pipetting 5.00mL migration has in 50mL
It fills in centrifuge tube, 0.5g sodium chloride and 5mL ethyl acetate is separately added into centrifuge tube, add the storage of 20uL diethyl naphthalene internal standard
Standby liquid, ultrasonic extraction 15min take supernatant liquid to analyze for GC-MS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910548459.8A CN110376299A (en) | 2019-06-24 | 2019-06-24 | The measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910548459.8A CN110376299A (en) | 2019-06-24 | 2019-06-24 | The measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110376299A true CN110376299A (en) | 2019-10-25 |
Family
ID=68250615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910548459.8A Pending CN110376299A (en) | 2019-06-24 | 2019-06-24 | The measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110376299A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111595965A (en) * | 2020-05-11 | 2020-08-28 | 中国包装科研测试中心 | Method for detecting transport amount of isoprene in packaging material |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000027787A1 (en) * | 1998-11-06 | 2000-05-18 | Eastman Chemical Company | Method of producing acetoxyaryl carboxylic acids |
| CN104380190A (en) * | 2012-06-15 | 2015-02-25 | 株式会社理光 | Recording medium, image recording device, and image recording set |
| CN105102532A (en) * | 2013-02-27 | 2015-11-25 | 太阳化学公司 | Polyvinyl alcohol and ethylene vinyl alcohol copolymer barrier coatings |
| CN105301133A (en) * | 2015-11-12 | 2016-02-03 | 中华人民共和国张家口出入境检验检疫局 | Method for detecting 2,6-diisopropyl naphthalene residual quantity in food |
| CN106053694A (en) * | 2016-06-23 | 2016-10-26 | 福清出入境检验检疫局综合技术服务中心 | Method for detecting residual amount of 2,6-diisopropylnaphthalene in food |
| CN107389811A (en) * | 2017-07-05 | 2017-11-24 | 江苏中烟工业有限责任公司 | The assay method of diisopropyl naphthalene in cigarette tipping paper |
-
2019
- 2019-06-24 CN CN201910548459.8A patent/CN110376299A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000027787A1 (en) * | 1998-11-06 | 2000-05-18 | Eastman Chemical Company | Method of producing acetoxyaryl carboxylic acids |
| CN104380190A (en) * | 2012-06-15 | 2015-02-25 | 株式会社理光 | Recording medium, image recording device, and image recording set |
| CN105102532A (en) * | 2013-02-27 | 2015-11-25 | 太阳化学公司 | Polyvinyl alcohol and ethylene vinyl alcohol copolymer barrier coatings |
| CN105301133A (en) * | 2015-11-12 | 2016-02-03 | 中华人民共和国张家口出入境检验检疫局 | Method for detecting 2,6-diisopropyl naphthalene residual quantity in food |
| CN106053694A (en) * | 2016-06-23 | 2016-10-26 | 福清出入境检验检疫局综合技术服务中心 | Method for detecting residual amount of 2,6-diisopropylnaphthalene in food |
| CN107389811A (en) * | 2017-07-05 | 2017-11-24 | 江苏中烟工业有限责任公司 | The assay method of diisopropyl naphthalene in cigarette tipping paper |
Non-Patent Citations (3)
| Title |
|---|
| C. SIMONEAU等: "Identification and quantification of the migration of chemicals from plastic baby bottles used as substitutes for polycarbonate", 《FOOD ADDITIVES AND CONTAMINANTS》 * |
| VASILEIOS I等: "Migration studies from recycled paper packaging materials: development of an analytical method for rapid testing", 《ANALYTICA CHIMICA ACTA》 * |
| 王娟娟等: "烟用接装纸中二异丙基萘的测定", 《云南化工》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111595965A (en) * | 2020-05-11 | 2020-08-28 | 中国包装科研测试中心 | Method for detecting transport amount of isoprene in packaging material |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Ding et al. | Rapid micropreparation procedure for the gas chromatographic–mass spectrometric determination of BHT, BHA and TBHQ in edible oils | |
| Dong et al. | Multi-walled carbon nanotubes as solid-phase extraction sorbents for simultaneous determination of type A trichothecenes in maize, wheat and rice by ultra-high performance liquid chromatography-tandem mass spectrometry | |
| Lim et al. | Improvement of accuracy for the determination of vitamin A in infant formula by isotope dilution-liquid chromatography/tandem mass spectrometry | |
| CN104007218B (en) | The assay method of bisphenol S migration amount in a kind of plastic food packaging materials | |
| CN102230918A (en) | Method for determining benzene and benzene series contents in flavor and spices for cigarettes | |
| CN104569256A (en) | Method for determining three types of isothiazolinone preservatives in water-based glue by adopting liquid chromatography-tandem mass spectrum | |
| CN102253140A (en) | Method for testing content of benzene and benzene series in water base adhesive for tobaccos | |
| CN104655753B (en) | The assay method of 3-acetyl group-2,5-thioxene in a kind of food additive | |
| CN110376299A (en) | The measuring method of diisopropyl naphthalene the amount of migration in silicone oil paper | |
| CN104535666A (en) | A method of measuring migration amounts of eighteen phthalic acid esters in a conveyor belt by adopting a gas chromatography-mass spectrometry instrument | |
| CN102565258A (en) | Method for measuring benzophenone and 4-methylbenzophenone in cigarette packing material | |
| Turak et al. | Simultaneous determination of allura red and ponceau 4r in drinks with the use of four derivative spectrophotometric methods and comparison with high-performance liquid chromatography | |
| Zougagh et al. | Use of non-aqueous capillary electrophoresis for the quality control of commercial saffron samples | |
| CN104535705A (en) | Method for synchronously measuring capsaicin and capsorubin in capsicum oleoresin | |
| CN106018592A (en) | Quantitative analysis method for polychlorobiphenyls in dry food packaging paper | |
| Surh et al. | Simultaneous determination of 4-hydroxy-2-alkenals, lipid peroxidation toxic products | |
| CN109187831A (en) | Using the method for 9 kinds of alcohol compound contents in GC-MS Rapid Simultaneous Determination alcohol | |
| CN107543878A (en) | A kind of method that 3 kinds of OIT preservatives in cigarette paper are determined using Liquid Chromatography-Tandem Mass Spectrometry | |
| Altuntas et al. | Quantitative determination of acrivastine and pseudoephedrine hydrochloride in pharmaceutical formulation by high performance liquid chromatography and derivative spectrophotometry | |
| CN109187830A (en) | The method of 9 kinds of alcohol compound contents in GC-MS method Rapid Simultaneous Determination edible essence fragrance | |
| Sharma et al. | Validated simultaneous spectrophotometric estimation of paroxetine HCL bulk and tablet dosage form using ferric chloride | |
| CN104880526A (en) | Method for determining content of benzyl glucosinolate in lepidium meyenii walp | |
| Zong et al. | Optimization and validation of an HPLC-photodiode array detector method for determination of organic acids in vinegar | |
| d’Oliveira et al. | Development and analytical validation of the methodology for vitamins in tablets by ultra-performance liquid chromatography | |
| CN107727764A (en) | Chloroethanes and the automatic headspace sampling gas chromatography of chloroform residual in a kind of measure aureomycin hydrochloride |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191025 |