CN110367460A - A kind of grifola frondosa day shellfish compound formulation improving spacefarer's constitution - Google Patents
A kind of grifola frondosa day shellfish compound formulation improving spacefarer's constitution Download PDFInfo
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- CN110367460A CN110367460A CN201910740509.2A CN201910740509A CN110367460A CN 110367460 A CN110367460 A CN 110367460A CN 201910740509 A CN201910740509 A CN 201910740509A CN 110367460 A CN110367460 A CN 110367460A
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- Prior art keywords
- grifola frondosa
- spacefarer
- saussurea involucrata
- day shellfish
- constitution
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- 240000001080 Grifola frondosa Species 0.000 title claims abstract description 59
- 235000007710 Grifola frondosa Nutrition 0.000 title claims abstract description 59
- 235000015170 shellfish Nutrition 0.000 title claims abstract description 52
- 239000000203 mixture Substances 0.000 title claims abstract description 36
- 150000001875 compounds Chemical class 0.000 title claims abstract description 32
- 238000009472 formulation Methods 0.000 title claims abstract description 31
- 241001145025 Saussurea involucrata Species 0.000 claims abstract description 51
- 239000000843 powder Substances 0.000 claims abstract description 26
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 20
- 241000208340 Araliaceae Species 0.000 claims abstract description 16
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 16
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 16
- 235000008434 ginseng Nutrition 0.000 claims abstract description 16
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 10
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 10
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 10
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 10
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 10
- 239000011718 vitamin C Substances 0.000 claims abstract description 10
- 238000000227 grinding Methods 0.000 claims abstract description 7
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 239000001963 growth medium Substances 0.000 claims description 17
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 13
- 229910052711 selenium Inorganic materials 0.000 claims description 13
- 239000011669 selenium Substances 0.000 claims description 13
- 239000003375 plant hormone Substances 0.000 claims description 12
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 12
- NWBJYWHLCVSVIJ-UHFFFAOYSA-N N-benzyladenine Chemical compound N=1C=NC=2NC=NC=2C=1NCC1=CC=CC=C1 NWBJYWHLCVSVIJ-UHFFFAOYSA-N 0.000 claims description 9
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 210000000056 organ Anatomy 0.000 claims description 8
- GEWDNTWNSAZUDX-WQMVXFAESA-N (-)-methyl jasmonate Chemical compound CC\C=C/C[C@@H]1[C@@H](CC(=O)OC)CCC1=O GEWDNTWNSAZUDX-WQMVXFAESA-N 0.000 claims description 7
- 229920001661 Chitosan Polymers 0.000 claims description 7
- 241000196324 Embryophyta Species 0.000 claims description 7
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims description 7
- 229940041514 candida albicans extract Drugs 0.000 claims description 7
- GEWDNTWNSAZUDX-UHFFFAOYSA-N methyl 7-epi-jasmonate Natural products CCC=CCC1C(CC(=O)OC)CCC1=O GEWDNTWNSAZUDX-UHFFFAOYSA-N 0.000 claims description 7
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims description 7
- 239000012138 yeast extract Substances 0.000 claims description 7
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 6
- 229960004889 salicylic acid Drugs 0.000 claims description 6
- 238000000338 in vitro Methods 0.000 claims description 5
- 239000011812 mixed powder Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 210000001519 tissue Anatomy 0.000 claims description 4
- 241000206575 Chondrus crispus Species 0.000 claims description 3
- FAIXYKHYOGVFKA-UHFFFAOYSA-N Kinetin Natural products N=1C=NC=2N=CNC=2C=1N(C)C1=CC=CO1 FAIXYKHYOGVFKA-UHFFFAOYSA-N 0.000 claims description 3
- OTCCIMWXFLJLIA-BYPYZUCNSA-N N-acetyl-L-aspartic acid Chemical compound CC(=O)N[C@H](C(O)=O)CC(O)=O OTCCIMWXFLJLIA-BYPYZUCNSA-N 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 108010079058 casein hydrolysate Proteins 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 claims description 3
- 230000004069 differentiation Effects 0.000 claims description 3
- QANMHLXAZMSUEX-UHFFFAOYSA-N kinetin Chemical compound N=1C=NC=2N=CNC=2C=1NCC1=CC=CO1 QANMHLXAZMSUEX-UHFFFAOYSA-N 0.000 claims description 3
- 229960001669 kinetin Drugs 0.000 claims description 3
- 210000001161 mammalian embryo Anatomy 0.000 claims description 3
- YGGXZTQSGNFKPJ-UHFFFAOYSA-N methyl 2-naphthalen-1-ylacetate Chemical compound C1=CC=C2C(CC(=O)OC)=CC=CC2=C1 YGGXZTQSGNFKPJ-UHFFFAOYSA-N 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 229940091258 selenium supplement Drugs 0.000 claims description 3
- 235000000346 sugar Nutrition 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 3
- 210000001938 protoplast Anatomy 0.000 claims description 2
- 238000012549 training Methods 0.000 claims description 2
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 241000222684 Grifola Species 0.000 abstract description 12
- 208000002173 dizziness Diseases 0.000 abstract description 12
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 5
- 235000013305 food Nutrition 0.000 abstract description 4
- 239000004615 ingredient Substances 0.000 abstract description 3
- 238000012545 processing Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 10
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- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 150000002632 lipids Chemical class 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 206010018910 Haemolysis Diseases 0.000 description 4
- 244000205939 Rhizopus oligosporus Species 0.000 description 4
- 235000000471 Rhizopus oligosporus Nutrition 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 244000046052 Phaseolus vulgaris Species 0.000 description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 3
- 230000008588 hemolysis Effects 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 229920001503 Glucan Polymers 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 2
- 235000008696 isoflavones Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 240000000203 Salix gracilistyla Species 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000001772 anti-angiogenic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000032459 dedifferentiation Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000005486 microgravity Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 210000002706 plastid Anatomy 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 235000013548 tempeh Nutrition 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H4/00—Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
- A01H4/001—Culture apparatus for tissue culture
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H4/00—Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
- A01H4/005—Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
- A23L11/50—Fermented pulses or legumes; Fermentation of pulses or legumes based on the addition of microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Developmental Biology & Embryology (AREA)
- Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention belongs to food processing technology fields, more particularly to a kind of grifola frondosa day shellfish compound formulation for improving spacefarer's constitution.A kind of grifola frondosa day shellfish compound formulation improving spacefarer's constitution, raw material are made of day shellfish powder, grifola frondosa, ginseng, rhizoma polygonati, Saussurea involucrata culture, vitamin C, maltodextrin and oligofructose；The effective ingredient in grifola frondosa day shellfish compound formulation is fully absorbed by human body to significantly improve the absorptivity of grifola frondosus D resistance point in human body grifola frondosa by Saussurea involucrata culture and the grinding of the mixing broken wall of grifola frondosa and the addition of day shellfish powder；It effectively prevent spacefarer under state of weightlessness, the dizziness and gastrointestinal tract variation issue of generation.
Description
Technical field
The invention belongs to food processing technology fields, more particularly to a kind of grifola frondosa day Bei Fuhe for improving spacefarer's constitution
Preparation.
Background technique
Spacefarer be as a kind of special crowd, during space travel, due to raying, microgravity, magnetic field and
The influence of Diurnal blood pressure rhythm causes metabolism and physiological status disorder in vivo, specially spacefarer's disorders of digestion, immune function
It can decline, directly affect the work and health of spacefarer.Its shellfish (Tempeh) is also known as red shellfish, day training, is by the big of boiling
Beans further ferment and the Fermented bean product that are formed.The day shellfish that fermentation is completed is a kind of good protein food source, wind
Interest sense is good, nutritive value is high, the isoflavone rich in high activity, a variety of free amino acids, unsaturated fatty acid, B race dimension
The nutriments such as raw element, tocopherol and antioxidant superoxide dismutase (SOD), studies have shown that these substances are for prevention and treatment
Obesity, diabetes, hyperlipidemia, high cholesterol, hypertension and cardiovascular and cerebrovascular, anticancer activity etc. have apparent effect, can also
Substitute as meat.
Grifola frondosa also known as, grifola frondosus is commonly called as " dance mushroom ", is food, medicine dual-purpose gill fungus bacterium, Chang Yesheng is around chestnut between summer and autumn.Son
Entity meat, short handle is in coralliform branch, is overlapped into clump, appearance, graceful, stacking is like chrysanthemum；Its smell, faint scent overflow,
It is refreshing；Its meat is crisp and refreshing, and hundred eat and do not mind.Side is combined into containing being combined into main chain β-(1-3) with β-(1-6) in grifola frondosa
The glucan of chain and the active glucan that main chain β-(1-6) is combined into side chain, also referred to as grifola frondosus D are combined into β-(1-3)
There is antitumor, Synergy and attenuation to strengthen the body resistance to consolidate the constitution for resistance point, grifola frondosus D resistance point, the effect of strengthening the spleen and replenishing qi.
Saussurea involucrata culture is to cultivate the in vitro plant organ of saussurea involucrata under controlled conditions, is cured its dedifferentiation generation
Injured tissue simultaneously gradually differentiates the plant body after organ.
Human body divides absorptivity lower grifola frondosus D resistance in day shellfish compound formulation in the prior art, and grinds by applicant
Discovery human body is studied carefully in the absorptivity to grifola frondosus D resistance point, and when absorption rate is lower than 16%, the basic nothing of grifola frondosus D resistance point
Method reaches its medicinal efficacy.
Summary of the invention
Object of the present invention is to provide a kind of grifola frondosa day shellfish compound formulation for improving spacefarer's constitution, solve in the prior art
Grifola frondosa day shellfish compound formulation effective ingredient human body utilization rate it is low, can not effectively solve spacefarer and easily go out under long-term state of weightlessness
The technical issues of existing brain dizziness and gastrointestinal tract change.
To achieve the goals above, the specific technical solution of the present invention is:
A kind of grifola frondosa day shellfish compound formulation improving spacefarer's constitution, raw material is by day shellfish powder, grifola frondosa, ginseng, rhizoma polygonati, saussurea involucrata
Culture, vitamin C, maltodextrin and oligofructose composition；Saussurea involucrata culture preparation, it is aseptically that saussurea involucrata is in vitro
Plant organ, tissue, cell, embryo or Protoplast cuhnre are on saussurea involucrata culture medium；Wherein saussurea involucrata culture medium by MS culture medium,
Selenium, salicylic acid, yeast extract, plant hormone 6-BA, plant hormone NAA, phenylalanine, methyl jasmonate and chitosan group
At；After the completion of Saussurea involucrata culture Organ Differentiation, Saussurea involucrata culture is obtained；Grifola frondosa, the grinding of Saussurea involucrata culture mixing broken wall, broken wall
90% or more rate；Ginseng and rhizoma polygonati individually carry out broken wall grinding, obtain ginseng pulverate and rhizoma polygonati powder；Grifola frondosa, Saussurea involucrata culture mixing
Powder is mixed with ginseng pulverate, rhizoma polygonati powder, day shellfish powder, vitamin C, maltodextrin and oligofructose, obtains finished product.
It further, include 46 μm of ol/L of selenium, salicylic acid 0.5mg/L, yeast extract 11g/ in the saussurea involucrata culture medium
L, plant hormone 6-BA 0.5mg/L, plant hormone NAA 1.5mg/L, phenylalanine 13mg/L, 35 μm of ol/L of methyl jasmonate,
Caseinhydrolysate 100mg/L and chitosan 15mg/L.
Further, it is described improve spacefarer's constitution grifola frondosa day shellfish compound formulation include 15 parts of day shellfish powder, 9 parts of grifola frondosa,
6 parts of ginseng, 3.5 parts of rhizoma polygonati, 9 parts of Saussurea involucrata culture, 0.5 part of vitamin C, 1.2 parts of maltodextrin and 0.8 part of oligofructose.
Further, grifola frondosa and Saussurea involucrata culture mixed powder broken wall grind size are 260 mesh.
Further, MS culture medium is 4736mg/L, citric acid 25mg/L, 6-benzyl aminopurine 4mg/L, methyl α-naphthyl acetate
0.05mg/L, 6-Furfurylaminopurine 1.5mg/L, sugar 29000mg/L and carragheen 7000mg/L.
Further, the grifola frondosa day shellfish compound formulation for improving spacefarer's constitution can be tablet, pill, capsule or powder
One of shape.
The utility model has the advantages that by the way that selenium element is added in Saussurea involucrata culture incubation, to make to contain in Saussurea involucrata culture
Higher selenium element, by Saussurea involucrata culture and the grinding of the mixing broken wall of grifola frondosa and the addition of day shellfish powder, to significantly improve
The absorptivity of grifola frondosus D resistance point, makes the effective ingredient in grifola frondosa day shellfish compound formulation be absorbed by the body and more fills in human body grifola frondosa
Point；By the addition of day shellfish powder, to further improve human body to the absorptivity of grifola frondosus D resistance point, and human body is improved
To the absorption efficiency of the entire grifola frondosa day shellfish compound formulation nutrition for improving spacefarer's constitution；So that improving spacefarer's constitution
Grifola frondosa day shellfish compound formulation has the function of better anti-oxidant, anticancer, inhibits tumour, norcholesterol, adjusts blood lipid, preferably
Reducing blood lipid, haemolysis, improve immunity function can effectively prevent spacefarer under state of weightlessness, the dizziness and gastrointestinal tract of generation
Variation issue.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment
Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
Embodiment 1, it is a kind of improve spacefarer's constitution grifola frondosa day shellfish compound formulation, raw material by day shellfish powder, grifola frondosa, ginseng,
Rhizoma polygonati, Saussurea involucrata culture, vitamin C, maltodextrin and oligofructose composition.
Saussurea involucrata culture preparation, aseptically by the in vitro plant organ of saussurea involucrata, tissue, cell, embryo or primary
Plastid culture is on saussurea involucrata culture medium；Wherein saussurea involucrata culture medium is swashed by MS culture medium, selenium, salicylic acid, yeast extract, plant
Plain 6-BA, plant hormone NAA, phenylalanine, methyl jasmonate and chitosan composition；Specifically wherein MS culture medium is
4736mg/L, citric acid 25mg/L, 6-benzyl aminopurine 4mg/L, methyl α-naphthyl acetate 0.05mg/L, 6-Furfurylaminopurine 1.5mg/L,
Sugared 29000mg/L, carragheen 7000mg/L.It also include selenium 46 μm of ol/L, bigcatkin willows on MS culture medium in the saussurea involucrata culture medium
Sour 0.5mg/L, yeast extract 11g/L, plant hormone 6-BA 0.5mg/L, plant hormone NAA 1.5mg/L, phenylalanine
13mg/L, 35 μm of ol/L of methyl jasmonate, caseinhydrolysate 100mg/L and chitosan 15mg/L.The in vitro object aseptic inoculation of saussurea involucrata
Afterwards, 25 DEG C of constant temperature and humidity cultures complete the Saussurea involucrata culture containing selenium needed for obtaining to Saussurea involucrata culture Organ Differentiation.
The day shellfish bacterium powder is that Rhizopus oligosporus bacterium (Rhizopusoligosporus) fermentation is prepared.It specifically will be big
Beans carry out extruding, then mix it according to mass ratio 1:2 with flour after rehydration, are then inoculated with Rhizopus oligosporus bacterium
(Rhizopusoligosporus) it is fermented to obtain a day shellfish, be then freeze-dried, then pass through 1000 mesh wall-broken grinders
Broken wall is carried out to crush for use.
Next grifola frondosa, Saussurea involucrata culture mixing broken wall are ground, 90% or more sporoderm-broken rate；Ginseng and rhizoma polygonati is independent
Broken wall grinding is carried out, ginseng pulverate and rhizoma polygonati powder are obtained；By grifola frondosa, Saussurea involucrata culture mixed powder and ginseng pulverate, rhizoma polygonati powder, day shellfish
Powder, vitamin C, maltodextrin and oligofructose mixing, obtain finished product.
The grifola frondosa day shellfish compound formulation for improving spacefarer's constitution can be one in tablet, pill, capsule or powdery
Kind.Sheet is preferably made.
It include 46 μm of ol/L of selenium, salicylic acid 0.5mg/L, yeast extract 11g/L, plant hormone in the saussurea involucrata culture medium
6-BA 0.5mg/L, plant hormone NAA 1.5mg/L, phenylalanine 13mg/L, methyl jasmonate 35 μm of ol/L, caseinhydrolysates
100mg/L and chitosan 15mg/L.
In order to make the grifola frondosa day shellfish compound formulation of the present invention for improving spacefarer's constitution, there is higher absorption of human body
Efficiency, and with better anti-oxidant, anticancer, inhibition tumour, norcholesterol, adjusting blood lipid, haemolysis, the work for improving immunity
With.Further, the grifola frondosa day shellfish compound formulation for improving spacefarer's constitution includes day shellfish powder 15kg, grifola frondosa 9kg, ginseng
Kg, rhizoma polygonati 3.5kg, Saussurea involucrata culture 9kg, 0.5 kg of vitamin C, maltodextrin 1.2kg and oligofructose 0.8kg.
In order to obtain better assimilation effect, and hinder the grifola frondosus D in grifola frondosa point to there is higher absorption efficiency, dance
Fine and soft and Saussurea involucrata culture mixed powder broken wall grind size is 230 mesh.
Grifola frondosa for invigorating the spleen, improve resistance, anticancer, antitumor, grifola frondosus D resistance point especially wherein included is for disliking
Property tumour and cancer all have extraordinary booster action, but human body is very low to its absorptivity, and lower absorptivity makes
The effect of grifola frondosa plays very limited；By the way that selenium element is added in its culture medium in Saussurea involucrata culture cultivation, thus
Saussurea involucrata culture is set to become selenium-rich Saussurea involucrata culture；Its shellfish is rich in protein, fat, reduced sugar, dietary fiber and isoflavones, dimension
The nutrient substances such as raw element B12 with antibacterial, anti-oxidant, anti-hemolysis, anti-angiogenic contraction isoreactivity and have similar female sharp
The effect of element is a kind of excellent nutritional health food raw material；The present invention passes through grifola frondosa, selenium-rich Saussurea involucrata culture, day shellfish powder
Combination significantly improves human body to the absorption efficiency of grifola frondosus D resistance point, and improves the compound system of grifola frondosa day shellfish of spacefarer's constitution
Agent also has better anti-oxidant, raising resistance, anticancer and alleviates fatigue effect, and also has better anticancer, suppression
Tumour processed, norcholesterol, regulating blood lipid action, preferable reducing blood lipid, haemolysis improve immunity function and can effectively prevent navigating
Its member is under state of weightlessness, the dizziness and gastrointestinal tract variation issue of generation.
The grifola frondosa day shellfish compound formulation of raising spacefarer's constitution of the application preparation is tested, with mentioning in the application
The grifola frondosa day shellfish compound formulation of high spacefarer's constitution is experimental subjects, referred to as experimental group, with grifola frondosa powder and Saussurea involucrata culture powder
Respectively referring to 1, referring to 2, simulation space state of weightlessness is tested.Every group of experiment number is randomly selected 100 people, tests number of days
Then respectively 3 days, 5 days and 10 days carry out body detection to the personnel after experiment；Experimental result record is as follows.
As the result is shown when testing third day, the brain dizziness situation of part has been had already appeared in reference one and reference two,
And there are not malaise symptoms in the experimental group for taking the grifola frondosa day shellfish compound formulation produced by the invention for improving spacefarer's constitution；It is real
It tests when proceeding to the 5th day, brain dizziness occurs referring to large area in one, gastrointestinal discomfort has also and has part increase, and reference
Gastrointestinal discomfort large area increases in two, and dizziness has part increase, while also occurring gastrointestinal discomfort person in experimental group, but
Relative populations are less；Test the tenth day referring to a brain dizziness number it is more than half, gastrointestinal discomfort person number is relatively also more, and joins
More according to two gastrointestinal discomfort persons, relative cerebral dizziness is less, and experimental group brain dizziness only occurs 2, and digestive discomfort goes out
It is 3 existing, to centainly prevent relaxation effect the results show that individually taking grifola frondosa powder and having to brain dizziness, and take saussurea involucrata culture
Object is relatively preferable to gastrointestinal discomfort effect, and the grifola frondosa day shellfish compound formulation of raising spacefarer's constitution of the present patent application, then
In terms of brain dizziness and gastrointestinal discomfort, all there is preferable inhibitory effect.The combination of the two makes to improve spacefarer's constitution
Grifola frondosa day shellfish compound formulation plays synergistic function, promotes the effect of pre- anti-dazzle and gastrointestinal tract variation.
Claims (6)
1. a kind of grifola frondosa day shellfish compound formulation for improving spacefarer's constitution, it is characterised in that:
Raw material is made of day shellfish powder, grifola frondosa, ginseng, rhizoma polygonati, Saussurea involucrata culture, vitamin C, maltodextrin and oligofructose；
Saussurea involucrata culture preparation, aseptically by the in vitro plant organ of saussurea involucrata, tissue, cell, embryo or protoplast
Culture is on saussurea involucrata culture medium；Wherein saussurea involucrata culture medium is by MS culture medium, selenium, salicylic acid, yeast extract, plant hormone 6-
BA, plant hormone NAA, phenylalanine, methyl jasmonate and chitosan composition；After the completion of Saussurea involucrata culture Organ Differentiation, obtain
To Saussurea involucrata culture；
Grifola frondosa, the grinding of Saussurea involucrata culture mixing broken wall, 90% or more sporoderm-broken rate；
Ginseng and rhizoma polygonati individually carry out broken wall grinding, obtain ginseng pulverate and rhizoma polygonati powder；
Grifola frondosa, Saussurea involucrata culture mixed powder and ginseng pulverate, rhizoma polygonati powder, day shellfish powder, vitamin C, maltodextrin and oligofructose are mixed
It closes, obtains finished product.
2. the grifola frondosa day shellfish compound formulation according to claim 1 for improving spacefarer's constitution, it is characterised in that: the saussurea involucrata
Include 46 μm of ol/L of selenium, salicylic acid 0.5mg/L, yeast extract 11g/L, plant hormone 6-BA 0.5mg/L, plant in culture medium
Object hormone NAA1.5mg/L, phenylalanine 13mg/L, 35 μm of ol/L of methyl jasmonate, caseinhydrolysate 100mg/L and chitosan
15mg/L。
3. the grifola frondosa day shellfish compound formulation according to claim 1 for improving spacefarer's constitution, it is characterised in that: the raising
The grifola frondosa day shellfish compound formulation of spacefarer's constitution includes 15 parts of day shellfish powder, 9 parts of grifola frondosa, 6 parts of ginseng, 3.5 parts of rhizoma polygonati, saussurea involucrata culture
9 parts of object, 0.5 part of vitamin C, 1.2 parts of maltodextrin and 0.8 part of oligofructose.
4. a kind of grifola frondosa day shellfish compound formulation for improving spacefarer's constitution according to claim 1, it is characterised in that: grifola frondosa
It is 260 mesh with Saussurea involucrata culture mixed powder broken wall grind size.
5. a kind of grifola frondosa day shellfish compound formulation for improving spacefarer's constitution according to claim 1, it is characterised in that: MS training
Supporting base is 4736mg/L, citric acid 25mg/L, 6-benzyl aminopurine 4mg/L, methyl α-naphthyl acetate 0.05mg/L, 6-Furfurylaminopurine
1.5mg/L, sugar 29000mg/L and carragheen 7000mg/L.
6. a kind of grifola frondosa day shellfish compound formulation for improving spacefarer's constitution according to claim 1, it is characterised in that: described
The grifola frondosa day shellfish compound formulation for improving spacefarer's constitution can be one of tablet, pill, capsule or powdery.
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