CN110353752A - Heart coronaries Venous Occlusion device - Google Patents

Heart coronaries Venous Occlusion device Download PDF

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Publication number
CN110353752A
CN110353752A CN201910577330.XA CN201910577330A CN110353752A CN 110353752 A CN110353752 A CN 110353752A CN 201910577330 A CN201910577330 A CN 201910577330A CN 110353752 A CN110353752 A CN 110353752A
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China
Prior art keywords
conduit
sacculus
vein
venous occlusion
blood
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CN201910577330.XA
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CN110353752B (en
Inventor
李金山
郑帅
李丽
王旭东
张文超
崔建培
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Beijing Xinjian Technology Co.,Ltd.
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Beijing Conrad Medical Technology Co Ltd
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Priority to CN201910577330.XA priority Critical patent/CN110353752B/en
Publication of CN110353752A publication Critical patent/CN110353752A/en
Priority to PCT/CN2020/096475 priority patent/WO2020259358A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)

Abstract

The present invention provides a kind of heart coronaries Venous Occlusion device, is related to medical instruments field field.The occluding device includes the first conduit, first sacculus, the proximal end interconnecting piece of first conduit connects full mechanism, first balloon interior has accommodating space, first sacculus is connected to the distal end of first conduit, and the full mechanism makes first sacculus in expanded state by first conduit, the device is placed in vein, it is pushed into the blood in vein is counter in cardiac muscle, it avoids due to artery Vascular diseases, myocardial blood supply can not persistently be given, lead to myocardial ischemia, from the anti-blood that pushes away of vein to cardiac muscle, guarantee myocardial blood supply, avoid the occurrence of myocardial necrosis caused by No-reflow phenoment.

Description

Heart coronaries Venous Occlusion device
Technical field
The present invention relates to medical instruments fields, and in particular to a kind of heart coronaries Venous Occlusion device.
Background technique
Coronary circulation is and to transport metabolic waste to provide nutriment and oxygen required for it to heart itself. Be blood directly by aorta base portion coronary artery flow direction cardiac muscle inside capillary network finally by vein flow back to atrium dextrum, Right ventricle flows into left room, a kind of circulation of left room after entering back into lung's exchange.Coronary artery stenosis or obstruction in coronary circulation It will cause myocardial ischemia, anoxic or necrosis.
Acute myocardial infarction AMI is that coronary artery is acute, myocardial necrosis caused by duration hypoxic-ischemic.It is clinically to have more Violent and lasting retrosternal pain, rest and nitrate esters medicine are unable to complete incidence graph, increase with serum enzyme activities And progressive ECG Change, can complicated by arrhythmia, shock or heart failure, often can threat to life.This disease is American-European most normal See, there are about the raw myocardial infarctions of 1,500,000 human hairs every year in the U.S..China is in obvious ascendant trend in recent years, is newly sent to few 500,000 every year, Now suffer from least 2,000,000.
Acute myocardial infarction AMI mainly uses percutaneous coronary intervention to open occluding coronary arteries at present, however in recent years Clinic show that although the blood flow of patient's external membrane of heart occluded blood vessel is restored, occluded blood vessel dominated cardiac muscle it is untrue The hemoperfusion in tissue level is just being fully achieved, i.e., " No-reflow phenoment ".
Summary of the invention
(1) the technical issues of solving
In view of the deficiencies of the prior art, the present invention provides a kind of heart coronaries Venous Occlusion device, help to solve Certainly Coronary blood flow problem after Acute myocardial stalk Coronary Artery in patients restoration of blood flow.
(2) technical solution
In order to achieve the above object, the present invention is achieved by the following technical programs:
A kind of heart coronaries Venous Occlusion device, the occluding device include:
First conduit, the proximal end interconnecting piece of first conduit connect full mechanism;
First sacculus, first balloon interior have accommodating space, and first sacculus is remote with first conduit End connection, and the full mechanism makes first sacculus in expanded state by first conduit.
Preferably, the full mechanism includes:
Cavity, the inside cavity have accommodating space;
Piston, the piston is located in the accommodating space of the cavity, and the length of the accommodating space along the cavity Direction sliding.
Preferably, the occluding device further include:
Vacuum device, the vacuum device vacuumize the occluding device.
Preferably, the occluding device further include:
Second conduit, second conduit are located in first conduit, and, the proximal end of second conduit extends to institute It states outside the first conduit, the close end of second conduit is connected with full mechanism;The distal end of second conduit extends to institute State the outside of the first balloon distal;
Second sacculus, second sacculus are located at the distal end of second conduit, and are connected to second catheter interior;
Wherein, the full mechanism makes second sacculus in expanded state by second conduit.
Preferably, the occluding device further include:
Pipeline is perfused, the intrusion pipe road has in vitro perfusion import and internal priming outlet, and the perfusion pipeline is located at In first conduit, the in vitro perfusion import is extended to outside first catheter proximal end port, described to be poured out in vivo Mouth extends to the distal outer of first conduit.
Preferably, the occluding device further include:
Pressure monitoring unit, the pressure monitoring unit are used for the blood pressure of monitoring of cardiac coronary venous.
(3) beneficial effect
The present invention provides a kind of heart coronaries Venous Occlusion devices.Compared with prior art, have following beneficial Effect:
Heart coronaries Venous Occlusion device provided in an embodiment of the present invention leads to myocardial ischemia in obstruction of artery When, the first sacculus is placed in heart coronaries vein by performing the operation, mechanism is filled and the first sacculus is carried out by the first conduit Full, the accommodating space of the first balloon interior is filled, the state so that the first sacculus diametrically becomes larger, to realize that blocking is coronal Vein is close to one end of atrium dextrum, prevent the blood flow of vein is from being back to atrium dextrum, since normal myocardial cells blood flows out, Therefore it is blocked area blood pressure rise, the blood in the vein counter can moisten the vein microcirculation into cardiac muscle under pressure, The myocardial region of ischemic is adequately perfused, and guarantees myocardial blood supply.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with It obtains other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of the embodiment of the present invention;
Fig. 2 is the structural schematic diagram under the first sacculus of embodiment of the present invention contraction state;
Fig. 3 is the structural schematic diagram under the first sacculus of embodiment of the present invention expanded state;
Fig. 4 is the structural schematic diagram under the second sacculus of embodiment of the present invention contraction state;
Fig. 5 is the structural schematic diagram under the second sacculus of embodiment of the present invention contraction state.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, to the technology in the embodiment of the present invention Scheme is clearly and completely described, it is clear that and described embodiments are some of the embodiments of the present invention, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts The every other embodiment obtained, shall fall within the protection scope of the present invention.
In various embodiments of the present invention, " remote ", " close " is using operator as reference.For example, the first conduit " distal end " refers to the one end of the first conduit far from operator, conversely, " proximal end " of the first conduit then refers to the first lumen close to hand One end of art operator.
The embodiment of the present application is suffered from by providing a kind of heart coronaries Venous Occlusion device to solve Acute myocardial stalk After the blood flow of the external membrane of heart occluded blood vessel of person is restored, there is technical issues that;
Technical solution in the embodiment of the present application is in order to solve the above technical problems, general thought is as follows:
The first sacculus is placed in heart coronaries vein by performing the operation, fills mechanism by the first conduit to the first sacculus It is filled, the state so that the first sacculus diametrically becomes larger, blocks coronary venous close to one end of atrium dextrum to realize, so that The blood flow of vein cannot be back to atrium dextrum, and the blood in the vein counter can moisten the vein into cardiac muscle and micro- follow under pressure The myocardial region of ring, ischemic is adequately perfused, and guarantees myocardial blood supply.
In order to better understand the above technical scheme, in conjunction with appended figures and specific embodiments to upper Technical solution is stated to be described in detail.
As shown in Fig. 1~5, a kind of heart coronaries Venous Occlusion device, the occluding device includes the first conduit 2 and the One sacculus 1, wherein the proximal end interconnecting piece of first conduit 2 has full mechanism 4, has accommodating space inside first sacculus 1, should First sacculus 1 is connected to the distal end of first conduit 2, and the full mechanism 4 makes first sacculus by first conduit 2 1 is in expanded state.
Above-described embodiment is in the specific implementation process, wherein Fig. 2 is 1 contraction state of the first sacculus, and Fig. 3 is the first sacculus 1 Expanded state.When ischemic state is presented in cardiac muscle, the first sacculus 1 is placed in heart coronaries vein by performing the operation, fills mechanism 4 First sacculus 1 is filled by the first conduit 2, the accommodating space inside the first sacculus 1 is filled, so that the first sacculus 1 In expanded state, the first sacculus 1 under expanded state, which forms vein, to be blocked, to realize to blocking coronary venous close to the right heart The one end in room, prevent the blood flow of vein, from being back to atrium dextrum, the blood in the vein counter can moisten into the heart under pressure The vein microcirculation of flesh, the myocardial region of ischemic are adequately perfused, and guarantee myocardial blood supply.
A kind of heart coronaries Venous Occlusion device provided by the invention, the device are placed in vein, will be in vein Blood is counter to be pushed into cardiac muscle, is avoided due to artery Vascular diseases, can not persistently be given myocardial blood supply, be led to myocardial ischemia, from quiet The anti-blood that pushes away of arteries and veins guarantees myocardial blood supply, avoids the occurrence of myocardial necrosis caused by No-reflow phenoment to cardiac muscle.
In one embodiment, as shown in Figure 2-5, which includes inside cavity 401 and piston 402 cavity 401 With accommodating space, piston 402 is located in the accommodating space of the cavity 401, and the length of the accommodating space along cavity 401 Direction sliding.Specifically, when piston 402 generates reciprocating motion in cavity 401, piston 402 is by gas or liquid in cavity 401 The first conduit 2 is pushed to so that the first sacculus 1 is full.It should be noted that the sealing in order to promote piston 402, in piston Sealing ring 4021 is arranged in 402 side, and sealing ring 4021 is slided along 401 inner wall of cavity.
In the specific implementation process, it is also provided with motor 403, drives piston 402 in cavity 401 by motor 403 Middle generation moves back and forth, and the first sacculus 1 is filled and shunk.
In one embodiment, as shown in Figure 2-5, the occluding device further includes vacuum device 5, the vacuum device 5 The occluding device is vacuumized.Specific embodiment needs to vacuumize it before device work.
In addition, a triple valve is arranged in the proximal end of the first conduit 2 the embodiment of the invention also provides a kind of connection structure 201, vacuum device 5 and full mechanism 4 are separately connected by triple valve 201.It should be noted that may be used also in specific implementation To select other connection types as needed.
In one embodiment, as shown in Figures 4 and 5, the occluding device further includes the second conduit 701 and the second sacculus 7, and second Conduit 701 is located in the first conduit 2, and the proximal end of the second conduit 701 extends to outside first conduit 2, second conduit 701 close end is connected with full mechanism 4;The distal end of second conduit 701 extends to the outside of first sacculus 1, institute The inside for stating the second sacculus 7 is connected to the distal portion of second conduit 701;The full mechanism 4 passes through second conduit 701 make second sacculus 7 in expanded state.
Specifically, the full mechanism 4 that connect with above-mentioned first conduit 2, the full mechanism 4 that the second conduit 701 is connected can be with Using identical structure, the proximal end of the second conduit 701 also can connect vacuum device 5.
Occluding device is placed in heart when obstruction of artery leads to myocardial ischemia, by performing the operation by above-described embodiment In coronary venous, full mechanism fills the first sacculus by the first conduit, and the accommodating space of the first balloon interior is filled out It fills, so that the first sacculus is in expanded state, the first sacculus under expanded state forms blood to vein and blocks, and prevents in vein Blood to atrium dextrum flow so that be blocked to myocardium medium sized vein vessel inner blood pressure raising, fill in this case Mechanism fills the second sacculus by the second conduit, and the accommodating space of the second balloon interior is filled, so that the second sacculus In expanded state, since the second sacculus under expanded state forms blood expression to vein, to promote the blood in vein anti- It is pushed into cardiac muscle, so that ischemic region is adequately perfused, guarantees myocardial blood supply.It is segmented by more sacculus and blocks vein, increased The pressure of venous blood promotes the counter of venous blood to push back cardiac muscle, substantially ensures that myocardial ischemia area is adequately perfused, prevents the heart Myocardial ischemia necrosis.
In one embodiment, as shown in Figure 1, the occluding device further includes perfusion pipeline 3, the perfusion pipeline 3 has body Outer filling entrance and internal priming outlet, the drug release pipeline 3 are located in first conduit 2, and the in vitro perfusion enters Mouth extends to the outside of 2 proximal port of the first conduit, and the internal priming outlet extends to the outer of first sacculus 1 Portion is administered by drug release pipeline 3, to carry out drug adjuvant treatment.
In one embodiment, as shown in Figure 1, the occluding device further includes pressure monitoring unit 601, the pressure monitoring unit 601 are used for the blood pressure of monitoring of cardiac vein, and the pressure that the pressure monitoring unit 601 monitors passes through pressure monitoring unit pipes Road 6 reaches outside human body, which can be set in the first conduit 2, monitors the pressure of venous blood in real time Power prevents, injury of myocardium excessive with artery pressure difference in vein blood vessel during blocking, being blocked.
In conclusion compared with prior art, have it is following the utility model has the advantages that
First sacculus is placed in heart coronaries vein by the embodiment of the present invention by performing the operation, and works as obstruction of artery, and cardiac muscle is presented When ischemic state, full mechanism fills the first sacculus by the first conduit, and gas or liquid enter the first balloon interior Accommodating space in so that the first sacculus is in expanded state, the first sacculus under expanded state, which forms vein, to be blocked, and prevents hat Blood in shape vein is flowed to right ventricle, so that the pressure of venous blood improves, to promote the blood in vein is counter to be pushed into the heart In flesh, so that myocardial ischemia area obtains sufficient venous blood perfusion, prevent myocardial ischemia from leading to necrosis.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.In the absence of more restrictions, the element limited by sentence "including a ...", it is not excluded that There is also other identical elements in process, method, article or equipment including the element.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although with reference to the foregoing embodiments Invention is explained in detail, those skilled in the art should understand that: it still can be to aforementioned each implementation Technical solution documented by example is modified or equivalent replacement of some of the technical features;And these modification or Replacement, the spirit and scope for technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution.

Claims (6)

1. a kind of heart coronaries Venous Occlusion device, which is characterized in that the occluding device includes:
First conduit, the proximal end interconnecting piece of first conduit connect full mechanism;
First sacculus, first balloon interior have accommodating space, and the distal end of first sacculus and first conduit connects It is logical, and the full mechanism makes first sacculus in expanded state by first conduit.
2. heart coronaries Venous Occlusion device as described in claim 1, which is characterized in that the full mechanism includes:
Cavity, the inside cavity have accommodating space;
Piston, the piston is located in the accommodating space of the cavity, and the length direction of the accommodating space along the cavity Sliding.
3. heart coronaries Venous Occlusion device as described in claim 1, which is characterized in that the occluding device further include:
Vacuum device, the vacuum device vacuumize the occluding device.
4. heart coronaries Venous Occlusion device as described in claim 1, which is characterized in that the occluding device further include:
Second conduit, second conduit are located in first conduit, and, the proximal end of second conduit extends to described Outside one conduit, the close end of second conduit is connected with full mechanism;The distal end of second conduit extends to described The outside of one balloon distal;
Second sacculus, second sacculus are located at the distal end of second conduit, and are connected to second catheter interior;
Wherein, the full mechanism makes second sacculus in expanded state by second conduit.
5. heart coronaries Venous Occlusion device as described in claim 1, which is characterized in that the occluding device further include:
Pipeline is perfused, the intrusion pipe road has in vitro perfusion import and internal priming outlet, and the perfusion pipeline is located at described In first conduit, the in vitro perfusion import is extended to outside the proximal port of first conduit, the internal priming outlet Extend to the distal outer of first conduit.
6. heart coronaries Venous Occlusion device as described in claim 1, which is characterized in that the occluding device further include:
Pressure monitoring unit, the pressure monitoring unit are used for the blood pressure of monitoring of cardiac coronary venous.
CN201910577330.XA 2019-06-28 2019-06-28 Heart coronary vein blood flow blocking device Active CN110353752B (en)

Priority Applications (2)

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CN201910577330.XA CN110353752B (en) 2019-06-28 2019-06-28 Heart coronary vein blood flow blocking device
PCT/CN2020/096475 WO2020259358A1 (en) 2019-06-28 2020-06-17 Coronary venous blood flow blocking device

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Application Number Priority Date Filing Date Title
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Cited By (2)

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WO2020259357A1 (en) * 2019-06-28 2020-12-30 北京康瑞迪医疗科技有限公司 Coronary venous perfusion system and control method therefor
WO2020259358A1 (en) * 2019-06-28 2020-12-30 北京康瑞迪医疗科技有限公司 Coronary venous blood flow blocking device

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EP1199083A1 (en) * 2000-10-16 2002-04-24 Probitas Pharma, S.A. Apparatus for the inflation and deflation of balloon catheters and a method for its use
CN2537407Y (en) * 2002-04-12 2003-02-26 刘清泉 Multiple side hole embolism dissolving catheter with bag
WO2009035581A1 (en) * 2007-09-10 2009-03-19 Ziad Anwar Ali Intra-aortic multi-balloon catheter for improving coronary and visceral perfusion
CN106725696A (en) * 2017-02-13 2017-05-31 中国医科大学附属盛京医院 A kind of dual balloon catheter for blocking common iliac blood flow
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020259357A1 (en) * 2019-06-28 2020-12-30 北京康瑞迪医疗科技有限公司 Coronary venous perfusion system and control method therefor
WO2020259358A1 (en) * 2019-06-28 2020-12-30 北京康瑞迪医疗科技有限公司 Coronary venous blood flow blocking device

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