CN110339333A - A kind of lemon preserved with orange peel cream and preparation method thereof for treating chronic functional constipation - Google Patents
A kind of lemon preserved with orange peel cream and preparation method thereof for treating chronic functional constipation Download PDFInfo
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- CN110339333A CN110339333A CN201910775722.7A CN201910775722A CN110339333A CN 110339333 A CN110339333 A CN 110339333A CN 201910775722 A CN201910775722 A CN 201910775722A CN 110339333 A CN110339333 A CN 110339333A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of lemon preserved with orange peel cream and preparation method thereof for treating chronic functional constipation, which is made of each raw material of following parts by weight: 120 ~ 180 parts of brown sugar in pieces, 100 ~ 145 parts of lemon, 2 ~ 5 parts of dried orange peel, 8 ~ 14 parts of tag processed, 20 ~ 40 parts of ramulus cinnamomi, 30 ~ 50 parts of Radix Paeoniae Alba, 12 ~ 18 parts of rhizoma zingiberis, 15 ~ 25 parts of radix glycyrrhizae preparata, 20 ~ 35 parts of jujube, 12 ~ 18 parts of Rhizoma Atractylodis Macrocephalae, 18 ~ 30 parts of radix bupleuri, 7 ~ 16 parts of Fructus Aurantii, 10 ~ 20 parts and 6 ~ 15 parts of charred FRUCTUS CRATAEGI of Cortex Magnoliae Officinalis.The present invention is by the Chinese medicine and food of food and medicine consangunity, prescription is determined according to the principle that differential diagnosis in tcm treats, component compatibility is scientific and reasonable, has synergistic function between each component, plays warm kidney altogether and warms up spleen, soothing the liver dampness elimination, stomach function regulating moistening lung, qi-regulating of promoting the production of body fluid, pushes waste matter and the rotten dirty function of discharge.Instestinal motility can either be obviously increased, and softening stool can be continued, promotes light defecation, the present invention is not only quick, has no toxic side effect, but also without pharmacological dependence, curative effect is all good, effective percentage has significant curative effect up to 98% or more, for treating and preventing chronic functional constipation.
Description
Technical field
The present invention relates to functional food technical fields, in particular to a kind of dried orange peel lemon for treating chronic functional constipation
Lemon cream and preparation method thereof.
Background technique
Constipation is clinical common complicated symptom, comprising: awareness of defecation is few, and bowel frequency is few；Defecation is laborious, unsmooth；It is dry and hard excrement, hard
Just, the not clean sense of defecation；With abdominal pain or abdominal discomfort.Some patientss are also with constipation, agitation.As the course of disease be more than 6 months be
Chronic constipation.Illness rate of the constipation in crowd is up to 27%, and constipation can influence the people of each age group.Because constipation disease incidence is high,
The cause of disease is complicated, and patient often has manifold vexations, and prolonged constipation person can cause or aggravate recial disease, such as rectitis, anal fissure, hemorrhoid,
Simultaneously also with Behavioral disturbances such as constipation, agitation, dreaminess, depression and anxiety, quality of life will affect when constipation is serious.Cause
This treatment constipation is for maintaining one of human normal life physiological function, the essential means of social function.
Constipation can be divided into organic and functional two class from the cause of disease, be broadly divided into chronic mode transmission by pathogenesis and go out
Mouth two class of obstruction type.Clinical overwhelming majority chronic constipation is the indefinite functional disease of reason.Chronic functional constipation is controlled
Treatment scheme is to select corresponding remedy measures, including treatment of generally living, drug to control for possible pathogenic factors, pathogenesis
Treatment, biofeedback training and operative treatment.But the therapeutic effect of current chronic constipation is not good enough.Life treatment is Diet lifestyle
It corrects, advocates and increase dietary cellulosic and amount of drinking water, be suitable for chronic mode transmission and the two kinds of chronic function of Treatment of Outlet Obstruction Type
It can property constipation.But due to being the impact of main eating pattern and fast pace life mode by modern's high glucose and high fat high protein,
Most people can not take in enough dietary cellulosics and amount of drinking water in daily diet, constant cannot then work；Drug is controlled
Treat: (1) bulk-forming laxative mainly includes soluble cellulose (pectin, Asiatic plantain, oat bran etc.) and insoluble fibers (plant
Fiber, lignin etc.), the retentiveness of stool can be obviously increased, increases stool volume, then promotes intestines peristalsis, therefore change
Kind slow transit constipation effect is reliable, but due to being unable to improve outlet obstructed constipation etiology and pathogenesis, is not suitable as outlet stalk
The rapid defaecation of resistance type constipation is treated；(2) the common drug of permeability purgatives has lactulose, sorbierite, Macrogol 4000 etc.,
Due to obviously can quickly change the osmotic pressure of intestinal walls, reabsorption of the rectum to moisture, more promotion rectum moisture are not only reduced
It is directly entered excrement, the quick remedy measures suitable for Treatment of Outlet Obstruction Type chronic constipation persons such as excrement block caulkeds；But due to that can not increase
Add gastrointestinal motility efficiency, stool retentiveness can not be changed, it is bulk-forming to stool to be not improved, stimulating gastrointestinal road can not be continued
Power increases, and is not suitable as the long-term defaecation treatment of slow transit constipation；(3) demulcent cathartics such as enema, mineral oil
Or liquid paraffin, saline laxative such as magnesium sulfate, magnesia magma, intestinal wall can be lubricated, softening stool makes excrement be easy to be discharged, due to opening
Sai Lu use belongs to aggressive operation, mineral oil and paraffin poor taste, drinks into difficulty, and saline laxative can cause serious bad anti-
It answers, anthraquinone laxative prolonged application can cause colon melena disease or cathartic colon, cause between the atrophy of smooth muscle and damage myenteron
Neuropile aggravates constipation instead, reversible after drug withdrawal；Biofeedback therapy training patient relaxation pelvic diaphragm muscle in defecation, makes to arrange
Abdominal muscle, Pelvic floor group's coordination of action, can be used for the constipation patient of anorectum, Pelvic floor dysfunction, long-term efficacy when just
Preferably.Since drill program has no specific specifications, effect is restricted by operator and appointed condition, and effect is non-constant；Operation
It is invalid to treat all treatments above-mentioned to serious intractable constipation, if the constipation of Colonic transit activity obstruction type, serious patient
The traumatic and long-term effect for being contemplated that operative treatment, but performing the operation still there are still dispute, surgical effect by personnel, instrument,
Apparatus factor influences.
Based on this, patient needs a kind of effect stability, can may type, possible pathogenic factors, morbidity machine for constipation
System plays a role；And form of therapy and carrier are unified, therapeutic modality and effective dose standardization, treatment has no toxic side effect, nothing
Wound is not influenced by instrument and human factor, facilitates implementation, sustainable implementation, and can bring fine therapy experience to patient
New treatment means.
Summary of the invention
In view of the above shortcomings of the prior art, the object of the present invention is to provide a kind of chronic functional constipations for the treatment of
Lemon preserved with orange peel cream solves existing method there are curative effects unstable, toxic side effect, poor taste, treatment sustainability difference and applicable
The single problem of constipation type.
The present invention also provides a kind of preparation methods of lemon preserved with orange peel cream for treating chronic functional constipation, solve tradition
The structure of the nutriment of technique destructible is boiled, the effective content of active function substance is reduced.
In order to solve the above-mentioned technical problem, present invention employs the following technical solutions: a kind of to treat chronic functional just
Secret lemon preserved with orange peel cream is made of each raw material of following parts by weight: 120 ~ 180 parts of brown sugar in pieces, 100 ~ 145 parts of lemon, dried orange peel 2
~ 5 parts, 8 ~ 14 parts of tag processed, 20 ~ 40 parts of ramulus cinnamomi, 30 ~ 50 parts of Radix Paeoniae Alba, 12 ~ 18 parts of rhizoma zingiberis, 15 ~ 25 parts of radix glycyrrhizae preparata, jujube 20 ~ 35
Part, 12 ~ 18 parts of Rhizoma Atractylodis Macrocephalae, 18 ~ 30 parts of radix bupleuri, 7 ~ 16 parts of Fructus Aurantii, 10 ~ 20 parts and 6 ~ 15 parts of charred FRUCTUS CRATAEGI of Cortex Magnoliae Officinalis.
Further, the lemon preserved with orange peel cream of above-mentioned treatment chronic functional constipation further includes 80 ~ 90 parts of water-soluble dietary fiber
With 18 ~ 25 parts of xylo-oligosaccharide.In this way, the two kinds of fortifications of water-soluble dietary fiber and xylo-oligosaccharide are added in above-mentioned lotion
Agent, the good water solubility of the two are conducive to absorption of human body and utilization；Water-soluble dietary fiber can promote intestines peristalsis, and xylo-oligosaccharide can
Obviously quickly to change the osmotic pressure of intestinal walls, reabsorption of the rectum to moisture is reduced, rectum moisture is made to be directly entered excrement, and
Xylo-oligosaccharide is 10 ~ 20 times of fructose effect；Water-soluble dietary fiber and xylo-oligosaccharide synergistic effect can quickly increase stool
Water content, hence it is evident that increase intestines peristalsis function, to quickly solve constipation, and make patient's to be effectively improved the constipation time by original
Shortening to for 3 ~ 5 days in for 24 hours for formula, substantially increases therapeutic efficiency.
Further, the water-soluble dietary fiber is pectin (apple pectin, pomelo-pectin, blueberry pectin, pineapple pectin etc.
From the dietary fiber extracted in fruit), soyabean oligosaccharides, any one or a few in agar powder and carboxymethyl cellulose.
The present invention also provides the preparation methods of the lemon preserved with orange peel cream of above-mentioned treatment chronic functional constipation, including following step
It is rapid:
1) tag, ramulus cinnamomi, Radix Paeoniae Alba, rhizoma zingiberis, radix glycyrrhizae preparata, jujube, Rhizoma Atractylodis Macrocephalae, radix bupleuri, Fructus Aurantii, Cortex Magnoliae Officinalis and charred FRUCTUS CRATAEGI processed are weighed and obtains medicine
Then material is added 4 ~ 6 times of water, impregnates 0.5 ~ 1h, be heated to boiling, it is spare to filter out medical fluid by 1 ~ 2h of continuous heating；Into the dregs of a decoction
The water for adding 4 ~ 6 times of the quality of medicinal material, is heated to boiling, and it is spare to filter out medical fluid by 1 ~ 2h of continuous heating；
2) medical fluid obtained step 1) merges, staticly settle 10 ~ for 24 hours, its whole supernatant is taken, then adds the supernatant
For heat to boiling, 2 ~ 3h of continuous heating obtains ointment；
The present invention leached by the heating of multiple medicinal material and in the ointment that staticly settles active constituent be it is water-soluble and point
Son amount is small, improves absorption and utilization of the human body to effective component of chinese medicine, while also avoiding the dregs of a decoction perishable, improves dried orange peel lemon
The shelf-life of lemon cream, and without the dregs of a decoction, it is in good taste.
3) dried orange peel and lemon are chopped into fourth, are then put into it in cup with brown sugar in pieces, then the cup is placed in boiling water bath
Middle 20 ~ 28h of stewing out of water, obtains leachate；
4) ointment by step 2 preparation is added in the leachate of step 3), stirs evenly, and continues 4 ~ 6h of stewing out of water, and reaction terminates
The cup is taken out afterwards, naturally cools to 30 ~ 35 DEG C, is then added water-soluble dietary fiber and xylo-oligosaccharide, stirs evenly,
Obtain the lemon preserved with orange peel cream.
In this way, heat foods temperature is allowed to remain at 100 DEG C in boiling water bath, heating power uniform balance does not glue not burnt, stew
Trophic structure is not destroyed, and the substances such as soluble protein, fructose, dietary fiber, amino acid in food, can be obtained in stewing
Sufficiently dissolution and reservation, avoids high temperature from making protein denaturation, nutrition is caused to destroy.
At 30 ~ 35 DEG C, physicochemical property is stable for water-soluble dietary fiber and xylo-oligosaccharide, makees convenient for substantially stabilized performance
With.
Further, the density of the ointment is 1.2, effectively increases the content of the effective component in ointment in this way, is enhanced
Drug effect, every 1 gram of ointment are equivalent to 2 ~ 5 grams of crude drug, and one the 2 of the common traditional Chinese medicine tanning techniques endured, and can retain raw medicine
In comparison the amount of material 0.6 ~ 0.75 just retains and says in the difference of crude drug amount, ointment of the present invention is common tanning technique
More than 3 times.Ointment density is too low perishable, the excessively a height of bitter taste of density, and mouthfeel is bad.
Further, the continuous heating temperature is 120 ~ 150 DEG C.If temperature is higher than 150 DEG C of soda acids for being easily destroyed medical fluid
Balance, causes drug effect to weaken；If temperature is unfavorable for moisture and evaporates from medical fluid thoroughly lower than 120 DEG C, cause in ointment effectively at
Divide concentration to reduce, weakens curative effect.
Further, the medicinal material is also needed to be baked to be subsequently placed in carry out crushing at -10 ~ -30 DEG C before immersion and is made
Ultramicro-powder, the granularity of the Ultramicro-powder are 300 ~ 450 mesh.
In this way, the partial size of medicinal material is crushed to the powder that cell partial size is 48 μm (300 mesh) ~ 25 μm (500 mesh), make medicinal material grain
Degree reaches clasmatosis grade, makes directly to release between drug cell with intracellular effective component, improves effective component in drug
Dissolution rate and dissolution rate.It is crushed under the conditions of cryogenic freezing, each component is easily crushed to Ultramicro-powder, when colleague also reduces crushing
The frictional heat of generation protects material effective component, to reduce the loss of effective component in drug, retains original work
Property.
The property of medicine of Chinese medicine is as follows:
Tag processed: pungent, sweet, big heat, eliminating cold to stop pain, for numbness pain, contained partially with cold-dampness, arthralgia be more notably it is suitable, use it
Cold-dampness, antalgic can be dispelled.
Ramulus cinnamomi: there is expelling cold and relieving exterior syndrome, warming meridian, promote yang transforming qi, the effect of ramulus cinnamomi is to control exterior syndrome due to wind-cold, numbness and ache of cold dampness, four
The effect of limb is fainted cold, amenorrhea and algomenorrhea, hundred lump in the abdomen agglomerations, thoracic obstruction, palpitaition, phlegm retention, difficult urination, warming meridians and promoting circulation of qi.
Radix Paeoniae Alba: main perverse trend abdominal pain removes blood-arthralgia, break hard product fever and chills, hernia lump in the abdomen, analgesic, diuresis, QI invigorating, and nature and flavor be it is bitter,
Acid, it is slightly cold.
Rhizoma zingiberis: it is mild-natured, there is tonifying middle-Jiao and Qi, quench the thirst, strengthening spleen and tonifying lung, the effect of nourishes blood and promotes the production of body fluid.
Radix glycyrrhizae preparata: having the effect of tonifying spleen stomach function regulating, Yiqi and vein recovery, is used for weakness of the spleen and the stomach, fatigue and weakness, severe palpilation.
Jujube: taste sweet and neutral；Tonifying spleen stomach function regulating, nourishing generate fluid adjust battalion to defend, and solve poisoning of drug, control stomach void deficiency of food, the weak loose stool of spleen, qi and blood
Body fluid deficiency, disharmony between ying and wei, palpitation and severe palpitation, and married woman's stolen goods are hot-tempered." book on Chinese herbal medicine is new again ": " tonifying middle-Jiao and Qi, nourshing kidney warm stomach, controls the deficiency of Yin.
Rhizoma Atractylodis Macrocephalae: having the effect of strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention, is used for spleen eating less, abdominal distention diarrhea, phlegm retention
Feel dizzy and heart palpitations, oedema, spontaneous perspiration, threatened abortion.
Radix bupleuri: and in inducing diaphoresis, soothing liver-qi stagnation, yang invigorating, preventing malaria of bringing down a fever.For cold, fever, fevers and chills alternate, malaria,
Liver depression and qi stagnation, chest and rib distending pain.
Cortex Magnoliae Officinalis: warm-natured acrid flavour, hardship.Returns spleen, stomach, lung, large intestine channel.Effect: eliminating dampness dissolving phlegm, lower gas removes full.The major functions: for wet
In stagnant wound, abdominal swelling and diarrhea, stagnation of QI due to dyspepsia, abdominal distention constipation, sputum cough.
Charred FRUCTUS CRATAEGI: slightly warm in nature, it is sour, sweet.Returns spleen, stomach, Liver Channel.Containing organic acid such as chlorogenic acid, caffeic acid and tannin, tan
Acid anhydride, epicatechol, choline, acetylcholine, Sitosterolum, carrotene and vitamin C etc. have enhancing immunity of organisms,
Strengthening the spleen and stomach, digestant effect.
Clinical constipation with internal organs it is obstructed based on, mostly because spleen deficiency lose Yu Jianyun due to begin." the very dirty opinion of Plain Questions jade machine " cloud:
" spleen ... is too late then to make us nine orifices obstructed." modern life rhythm is fast, night life is abundant, along with abuse air-conditioning take it is cold, more
A series of unsound life styles such as ice-cold are eaten, human body is seriously damaged.Especially in area of some damp evils compared with Sheng, such as at
All, Guangzhou etc., People of the same tastes and habits like to be together, then the most easy impairment of the spleen of damp evil.Wu Ju Tong is said: " wetness hyperactivity then impotence." damp being a kind of YIN pathogen, sun of most easily hurting sb.'s feelings
Gas.Therefore taste yang-energies occur weak by modern, pushes mistake department or failure of qi transforming fluid, enteron aisle lose in make moist and be hard and dry as sheep dung it
It demonstrate,proves relatively common.And some patients are to defecate first to do, it is difficult to it is smoothly discharged, it is then again dilute half congealed.This card belongs to " watery diarrhea with hard fecal masses discharged at first and then undigested food ".Treatise on Febrile Diseases
191 bright instructions: " Yangming disease cannot be eaten, difficult urination if syncope due to pathogenic cold person, the right sweating of brothers, this being about to have watery diarrhea with hard fecal masses discharged, after hard at the beginning of must defecating
It is half congealed.Reason person, with cold in the stomach, indigested grain mixed with water therefore." the lunar sick lunar lesion of a piece of Zhong Jing behind points out that " lunar is
Disease, abdomen is full and pain, can't eat, very from interests, tripe abdomen from pain, if it is lower it, must sruffiness and rigidity in the epigastrium.
Therefore, the present invention uses tcm syndrome differentiation and typing, controls from internal organs are obstructed with the cold solidifying opinion of the deficiency of yang, monkshood system, rhizoma zingiberis add toast
For Radix Glycyrrhizae with tonifying spleen and kidney, ramulus cinnamomi adds Radix Paeoniae Alba with needle warming moxibustion, and radix bupleuri, Radix Paeoniae Alba, Fructus Aurantii and Radix Glycyrrhizae are with soothing the liver fortune spleen de-swelling, charred FRUCTUS CRATAEGI
Help digestion stomach function regulating, and Cortex Magnoliae Officinalis is with the aqueous vapor in row intestines, Rhizoma Atractylodis Macrocephalae invigorating the spleen for eliminating dampness, and by accurate reasonable compatibility between each component, all medicines are same
With playing warm kidney altogether and warm up spleen, soothing the liver dampness elimination pushes waste matter, and the rotten dirty function of discharge has the function that synergy.Further, this hair
Bright also compounding has brown sugar in pieces, lemon and dried orange peel, and brown sugar in pieces, lemon use dried orange peel and lemon as diet as fructose food sources
Fiber food source, in which: lemon: it is sour sweet, it is mild-natured, enter liver, stomach meridian, has the function of promoting the production of body fluid, invigorating the spleen.Dried orange peel: warm-natured taste
Bitter, pungent, return lung, the spleen channel have strengthening the spleen and stomach, ventilating, the effect of lowering the adverse-rising QI and eliminating phlegm.Rock sugar: it is sweet in flavor, it is mild-natured, enter spleen and lung warp,
With tonifying middle-Jiao and Qi, stomach function regulating moistening lung, relieving cough and reducing sputum effect.Three shares can stomach function regulating moistening lung, invigorating the spleen of promoting the production of body fluid, appetizing qi-regulating.It will be upper
State Chinese medicine production become liquid extract again with rock sugar, dried orange peel, lemon cream processed jointly.With top with using, warm kidney is played altogether and warms up spleen, soothing the liverization
Wet, stomach function regulating moistening lung, qi-regulating of promoting the production of body fluid push waste matter, the rotten dirty function of discharge.Have for the treatment and prevention of chronic functional constipation
Significant curative effect.
Compared with prior art, the invention has the following beneficial effects:
1, the present invention is by the Chinese medicine and food of food and medicine consangunity, determines prescription according to the principle that differential diagnosis in tcm treats, effect stability,
Prescription proportion science, does not add any artificial synthesis group point, and composition is natural, safe and non-toxic to have no stimulation, and takes safety, component
Compatibility is scientific and reasonable, and monkshood system, rhizoma zingiberis add radix glycyrrhizae preparata with tonifying spleen and kidney, and ramulus cinnamomi adds Radix Paeoniae Alba with needle warming moxibustion, radix bupleuri, Radix Paeoniae Alba, trifoliate orange
With soothing the liver fortune spleen de-swelling, charred FRUCTUS CRATAEGI helps digestion stomach function regulating for shell and Radix Glycyrrhizae, and Cortex Magnoliae Officinalis is with the aqueous vapor in row intestines, Rhizoma Atractylodis Macrocephalae invigorating the spleen for eliminating dampness, rock sugar, old
Skin and lemon share with stomach function regulating moistening lung, invigorating the spleen of promoting the production of body fluid, appetizing qi-regulating；There is synergistic function between component, play warm kidney altogether and warm up spleen,
Soothing the liver dampness elimination, stomach function regulating moistening lung, qi-regulating of promoting the production of body fluid push waste matter, the rotten dirty function of discharge.Instestinal motility, and energy can either be obviously increased
Enough lasting softening stool promotes light defecation, therefore equal for the possible type of constipation, possible pathogenic factors, pathogenesis effect
It is reliable and stable, there is significant curative effect for treating and preventing chronic functional constipation.
2, active constituent is equal in the ointment that the present invention is leached first and staticly settled by the heating of multiple medicinal material, is concentrated to get
It is small for water-soluble and molecular weight, absorption and utilization of the human body to effective component of chinese medicine are improved, Chinese medicine availability is improved and subtracts
Traditional Chinese Medicine dosage is lacked.Heat foods temperature is set to remain at 100 DEG C secondly, boiling water bath stews, heating power uniform balance does not glue not
Coke, stew trophic structure are not destroyed, and make nutriment, nature and flavor, effect that can retain to greatest extent and adequately dissolve.30 ~
Water-soluble dietary fiber and xylo-oligosaccharide are added at 35 DEG C, keeps the stabilization of its physicochemical property, stabilization plays a role, and avoids high temperature
Denaturation.By by Chinese medicine leaching, food boiling water bath stew and food enrichment add opportunity organically combine, make effectively
Under the precursor of ingredient dissolution, the activity of each effective component is remained to greatest extent, drug effect also accordingly enhances, to reduce medication
Dosage greatlys save raw medicinal material.
3, the present invention adheres to China's Chinese medicine preparation technology, in conjunction with modern food manufacture craft, realizes the dialectical principle treated
Determine prescription, Chinese medicine, food are made into the lemon preserved with orange peel cream of delicious beauty in food by medicine of residing, and patient is allowed to enjoy beautiful deliciousness
Meanwhile As the medicine took effect, the symptoms lessened and effectively prevention recurrence.The present invention is not only quick, has no toxic side effect, but also will not generate any
Pharmacological dependence, curative effect is all good, and effective percentage reaches 98% or more, be particularly suitable for because internal organs are obstructed and the deficiency of yang it is cold it is solidifying caused by
Chronic functional constipation has a good application prospect.
4, the present invention is using natural food as raw material, and technique adheres to that ancient method is recovered one's original simplicity, and formula has no toxic and side effect to human body.
Since form of therapy is food, taste sweet and sour taste, application method is oral diet, and to people's hurtless measure, patient is ready actively hard
It holds edible daily；The form of product is liquid extract, is individually packed with glass bottle, patient can be allowed to carry, and aspect is at any time
It is edible, it can be used for a long time.Lemon preserved with orange peel cream prepared by the present invention have it is beautiful delicious, conveniently, patient's medical treatment body-sensing is good, Bing Renzhu
Dynamic acceptance is high, and curative effect sustainability is strong, and formula manufacture craft is mature and standardizes, and eating method is normalized, no
It can be influenced by factors such as instrument, operators, effect, which can be stablized, to be showed, convenient for wider faster and better popularization.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail.
One, a kind of lemon preserved with orange peel cream and preparation method thereof for treating chronic functional constipation
Embodiment 1
A kind of lemon preserved with orange peel cream for treating chronic functional constipation, raw material proportioning are as follows: 1500 grams of brown sugar in pieces, 1250 grams of organic yellow lemons
Lemon, 25 grams of dried orange peels, 100 restrain tags, 300 grams of ramulus cinnamomi, 400 grams of Radix Paeoniae Albas, 150 grams of rhizoma zingiberis, 200 grams of radix glycyrrhizae preparatas, 300 grams of jujubes,
150 grams of Rhizoma Atractylodis Macrocephalaes, 200 grams of radix bupleuri, 100 grams of Fructus Aurantiis, 150 grams of Cortex Magnoliae Officinalis, 100 grams of charred FRUCTUS CRATAEGIs, 840 grams of apple pectins and 210 grams are oligomeric
Xylose.
Specific preparation method the following steps are included:
1) tag, ramulus cinnamomi, Radix Paeoniae Alba, rhizoma zingiberis, radix glycyrrhizae preparata, jujube, Rhizoma Atractylodis Macrocephalae, radix bupleuri, Fructus Aurantii, Cortex Magnoliae Officinalis and charred FRUCTUS CRATAEGI processed are dried respectively
It is dry, it is then respectively placed in and carries out crushing the Ultramicro-powder that 300 ~ 450 mesh are made under -20 DEG C of environment, then will be after the mixing of above-mentioned Ultramicro-powder
It is added in aluminum pot, 11000 grams of water is then added, impregnate 0.5h, be heated to boiling, it is standby to filter out medical fluid by 125 DEG C of continuous heating 1.5h
With；11000 grams of water are added into the dregs of a decoction, are heated to boiling, and it is spare to filter out medical fluid by 125 DEG C of continuous heating 1.5h.
2) medical fluid for obtaining step 1) merges, and staticly settles 12 hours, its whole supernatant is taken, then by the supernatant
Liquid small fire is heated to boiling, and 125 DEG C of continuous heating 3h obtain ointment, and test ointment specific gravity is 1.2, out 700 grams of ointment.
3) lemon is cleaned to net with 10% salt water, drained the water, impregnated lemon 2 hours with 0.9% physiological saline, be sliced into fourth,
Stoning, piece thickness 2-3mm, fourth diameter 1-2cm are spare；Dried orange peel is chopped into fourth, 0.3 ~ 0.5cm diameter is spare；Brown sugar in pieces is ground
Cheng Fen；Then the layering of rock sugar, lemon and dried orange peel is put into cup, then the cup is placed in boiling water bath in microcomputer electric saucepan and is selected
" nutrition is stewed " function, per half an hour stirring once prevent viscous pot, and middle stewing out of water 25h obtains leachate.
4) ointment by step 2 preparation is added in the leachate of step 3), stirs evenly, and continues 4 ~ 6h of stewing out of water, reaction
After the cup is taken out, naturally cool to 30 ~ 35 DEG C, be then added apple pectin and xylo-oligosaccharide, stir evenly, from
Cool down 3 ~ 4h so to get the lemon preserved with orange peel cream is arrived.
Embodiment 2
A kind of lemon preserved with orange peel cream for treating chronic functional constipation, raw material proportioning are as follows: 1200 grams of brown sugar in pieces, 1000 grams of lemons, 23
Gram dried orange peel, 90 restrain tags, 350 grams of ramulus cinnamomi, 420 grams of Radix Paeoniae Albas, 130 grams of rhizoma zingiberis, 180 grams of radix glycyrrhizae preparatas, 350 grams of jujubes, 160 grams it is white
Art, 250 grams of radix bupleuri, 140 grams of Fructus Aurantiis, 180 grams of Cortex Magnoliae Officinalis, 130 grams of charred FRUCTUS CRATAEGIs, 820 grams of carboxymethyl celluloses and 200 grams of oligomeric wood
Sugar.
Specific preparation method the following steps are included:
1) tag, ramulus cinnamomi, Radix Paeoniae Alba, rhizoma zingiberis, radix glycyrrhizae preparata, jujube, Rhizoma Atractylodis Macrocephalae, radix bupleuri, Fructus Aurantii, Cortex Magnoliae Officinalis and charred FRUCTUS CRATAEGI processed are dried respectively
It is dry, it is then respectively placed in and carries out crushing the Ultramicro-powder that 300 ~ 450 mesh are made under -20 DEG C of environment, then will be after the mixing of above-mentioned Ultramicro-powder
It is added in aluminum pot, 11000 grams of water is then added, impregnate 0.5h, be heated to boiling, it is standby to filter out medical fluid by 130 DEG C of continuous heating 1.5h
With；11000 grams of water are added into the dregs of a decoction, are heated to boiling, and it is spare to filter out medical fluid by 130 DEG C of continuous heating 1.5h.
2) medical fluid for obtaining step 1) merges, and staticly settles 12 hours, its whole supernatant is taken, then by the supernatant
Liquid small fire is heated to boiling, and 130 DEG C of continuous heating 3h obtain ointment, and test ointment specific gravity is 1.2, out 700 grams of ointment.
3) lemon is cleaned to net with 10% salt water, drained the water, impregnated lemon 2 hours with 0.9% physiological saline, be sliced into fourth,
Stoning, piece thickness 2-3mm, fourth diameter 1-2cm are spare；Dried orange peel is chopped into fourth, 0.3 ~ 0.5cm diameter is spare；Brown sugar in pieces is ground
Cheng Fen；Then the layering of rock sugar, lemon and dried orange peel is put into cup, then the cup is placed in boiling water bath in microcomputer electric saucepan and is selected
" nutrition is stewed " function, per half an hour stirring once prevent viscous pot, and middle stewing out of water 25h obtains leachate.
4) ointment by step 2 preparation is added in the leachate of step 3), stirs evenly, and continues 4 ~ 6h of stewing out of water, reaction
After the cup is taken out, naturally cool to 30 ~ 35 DEG C, be then added carboxymethyl cellulose and xylo-oligosaccharide, stirring is equal
It is even, 3 ~ 4h of natural cooling to get arrive the lemon preserved with orange peel cream.
Embodiment 3
A kind of lemon preserved with orange peel cream for treating chronic functional constipation, raw material proportioning are as follows: 1800 grams of brown sugar in pieces, 1200 grams of lemons, 30
Tags, 400 grams of ramulus cinnamomi, 500 grams of Radix Paeoniae Albas, 180 grams of rhizoma zingiberis, 150 grams of radix glycyrrhizae preparatas, 350 grams of jujubes, 120 grams are restrained in gram dried orange peel, 130
Rhizoma Atractylodis Macrocephalae, 180 grams of radix bupleuri, 80 grams of Fructus Aurantiis, 180 grams of Cortex Magnoliae Officinalis, 120 grams of charred FRUCTUS CRATAEGIs, 880 grams of apple pectins and 245 grams of xylo-oligosaccharides.
Specific preparation method the following steps are included:
1) tag, ramulus cinnamomi, Radix Paeoniae Alba, rhizoma zingiberis, radix glycyrrhizae preparata, jujube, Rhizoma Atractylodis Macrocephalae, radix bupleuri, Fructus Aurantii, Cortex Magnoliae Officinalis and charred FRUCTUS CRATAEGI processed are mixed and is added
In aluminum pot, 11000 grams of water are then added, impregnates 0.5h, is heated to boiling, it is spare to filter out medical fluid by 150 DEG C of continuous heating 1.5h；
11000 grams of water are added into the dregs of a decoction, are heated to boiling, and it is spare to filter out medical fluid by 150 DEG C of continuous heating 1.5h.
2) medical fluid for obtaining step 1) merges, and staticly settles 12 hours, its whole supernatant is taken, then by the supernatant
Liquid small fire is heated to boiling, and 150 DEG C of continuous heating 3h obtain ointment, and test ointment specific gravity is 1.2, out 700 grams of ointment.
3) lemon is cleaned to net with 10% salt water, drained the water, impregnated lemon 2 hours with 0.9% physiological saline, be sliced into fourth,
Stoning, piece thickness 2-3mm, fourth diameter 1-2cm are spare；Dried orange peel is chopped into fourth, 0.3 ~ 0.5cm diameter is spare；Brown sugar in pieces is ground
Cheng Fen；Then the layering of rock sugar, lemon and dried orange peel is put into cup, then the cup is placed in boiling water bath in microcomputer electric saucepan and is selected
" nutrition is stewed " function, per half an hour stirring once prevent viscous pot, and middle stewing out of water 25h obtains leachate.
4) ointment by step 2 preparation is added in the leachate of step 3), stirs evenly, and continues 4 ~ 6h of stewing out of water, reaction
After the cup is taken out, naturally cool to 30 ~ 35 DEG C, be then added apple pectin and xylo-oligosaccharide, stir evenly, from
Cool down 3 ~ 4h so to get the lemon preserved with orange peel cream is arrived.
Two, clinical test
The Efficacy of Traditional Chinese Medicine of constipation is that base is that diagnosis and treatment, i.e. scheme are personalized.Card type is more more than due to big functional disorder of intestine
Then therapy is complicated, and the excessively treatment of individuation then makes card type many and diverse, is unfavorable for the popularization of new drug large area developed.Then originally
Invention carries out the tcm syndrome distribution characteristics point of functional consitipation to the patient that diagnosis and treatment in 3 years are gone over by our hospital before determining formula
Analysis, specific as follows:
By the Patients with Functional Constipation of 2016 ~ 2018 Nian Jingzhi of taste section, our hospital according to generally acknowledged diagnostic criteria (with reference in China
The Chinese medicine disease for digest practice guidelines (in September, 2006) of medicine and pharmacology meeting the spleen-stomach diseases branch chief editor are to the diagnostic criteria of constipation Syndrome Types of TCM
And related literatures) screening, carry out Clinical Observation on Traditional Chinese Medical Syndrome.
As a result: patient 468 for collecting statistics available analysis altogether, research is found: 1, the tcm syndrome of Patients with Functional Constipation
Distribution is unrelated with the age, unrelated with gender, wherein common with simple syndrome.2, simple syndrome disposition feature are as follows: the obstructed card of internal organs
> syndrome of yang deficiency and coagulated cold > deficiency-weakness of spleen-QI demonstrate,proves > blood-stasis internal-depression card > enteron aisle excessive heat syndrome enteron aisle humidity hysteresis card.Wherein in all investigation cases
In, the patient for being related to the obstructed card of internal organs has 356, coverage rate 76.06%；Syndrome of yang deficiency and coagulated cold has 103, coverage rate 22.01%, and two
It is 98.07% that person, which merges coverage rate,.3, the obstructed card of internal organs and cold coagulate of the deficiency of yang are the most common Syndrome in TCM in our hospital's functional consitipation
It waits.
Efficacy evaluation:
1, fully recover: pathological symptom completely disappears, functional rehabilitation, without other lesions.
2, effective: the big portion of pathological symptom disappears, and function is restored substantially, without other lesions.
3, effectively: pathological symptom is substantially reduced, and function is restored, without other lesions.
4, invalid: pathological symptom improvement is unobvious, or has other syndromes.
16% is accounted within 0 ~ 18 years old in 468 patients, is accounted within 19 ~ 35 years old 13.2%, is accounted within 36 ~ 60 years old 46.7%, accounts for 24.1% within 60 years old or more.
It takes mode: using lemon preserved with orange peel cream 20ml/ times prepared by the present invention, melted with 200 ~ 300ml warm water, taken medicine before meals, one day
Three times, using effect is recorded.Recovery from illness 366,64 effective, 32 effective, 6 invalid, 98% or more total effective rate, the present invention
For the therapy and formula of the obstructed card of internal organs and the cold fixation card type for coagulating this Relatively centralized of the deficiency of yang, patient can significantly be allowed to restore normal
Defecation physiology.
Typical case:
Case one
Mr. Lin, female, 15 years old, usually constipation was not easy to be discharged, and takes tonneau medicine and enema takes a period of time fast, but multiple constipation again.
This is not in a position to examine five days, and abdomen turgor, implication are heavier.Pale tongue, greasy, weak pulse in tongue fur.Diagnosis: (internal organs are not activated yang for constipation
The cold of insufficiency type is solidifying).Take lemon preserved with orange peel cream of the present invention, prescription: lemon preserved with orange peel cream 20ml/ times is melted, before meals with 200-300ml warm water
Medication, three times per day.After 1 day, smooth discharge of defecating, and measure larger；It is continuous to take 5 days, normal defecation；Further consultation after 1 week, we are the same as use
2 months, normal defecation；Drug withdrawal further consultation in March, no relapse.
Case two
Liu, male, 65 years old.Difficulty in defecation is to be discharged for many years, and normal belching and acid returning phenomenon, borborygmus audio frequency is numerous, and arteries and veins is slow, in right arteries and veins partially, thin and delicate.It is double
Picture of taking is closed in very little discontented position, and ruler is slightly larger, obscure boundary.Dark tongue quality, tongue side is slightly purple, greasy and thin fur.Diagnosis: (internal organs are obstructed for constipation
The deficiency of yang is cold solidifying).Take lemon preserved with orange peel cream of the present invention, prescription: lemon preserved with orange peel cream 20ml/ times is melted, meal with 200-300ml warm water
Preceding medication, three times per day.Further consultation after 3 days, all diseases are improved；It is continuous to take 7 days, rear normal defecation；Further consultation after 10 days, Ben Fangtong
With 2 months, normal defecation；Drug withdrawal further consultation in March, no relapse.
Case three
Zhao, female, 45 years old, usually constipation was not easy loose stool after being discharged or being preceding just dry and hard, and enema is used for a long time, occasionally has
Hematochezia.This is not in a position to examine three days, and abdomen turgor, distending pain.Pale tongue, whitish tongue is greasy, weak pulse.Diagnosis: (internal organs are obstructed for constipation
The deficiency of yang is cold solidifying).Take lemon preserved with orange peel cream of the present invention, prescription: lemon preserved with orange peel cream 20ml/ times is melted, meal with 200-300ml warm water
Preceding medication, three times per day.After 1 day, smooth discharge of defecating, and measure larger；It is continuous to take 6 days, normal defecation；Further consultation after 1 week, Ben Fangtong
With 2 months, normal defecation；Drug withdrawal further consultation in March, no relapse.
Case four
Lee, male, 67 years old, constipation was not easy to be discharged more than 20 years, hemorrhoid 20 years, performed the operation 2 times, recently because of cold cough 2 months
Remaining, exacerbation is sent out in white foam phlegm, constipation again, with hematochezia.This is not in a position to examine four days, and abdomen turgor, distending pain.Tongue nature
Secretly, greasy and thin fur, weak pulse.Diagnosis: constipation (the obstructed deficiency of yang of internal organs is cold solidifying).Lemon preserved with orange peel cream of the present invention is taken, prescription: dried orange peel lemon
Lemon cream 20ml/ times is melted with 200 ~ 300ml warm water, is taken medicine before meals, three times per day.After 2 days, smooth discharge of defecating, and measure compared with
Greatly；It is continuous to take 5 days, normal defecation；Further consultation after 1 week, we are with 2 months, normal defecation；Drug withdrawal further consultation in March, no relapse.
To sum up, raw material of the present invention is simple and easy to get, and preparation method is simple, preparation easy to produce, which has warm kidney
Warm spleen, soothing the liver dampness elimination, stomach function regulating moistening lung, qi-regulating of promoting the production of body fluid push waste matter, the rotten dirty function of discharge, be effectively improved because internal organs are obstructed and/or
Cold coagulate of the deficiency of yang leads to chronic functional constipation, and curative effect is up to 98% or more, and curative effect is reliable and stable, has no toxic side effect, no medicine
Object dependence has good use value, application easy to spread.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not limitation with the present invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (8)
1. a kind of lemon preserved with orange peel cream for treating chronic functional constipation, which is characterized in that by each raw material group of following parts by weight
At: 120 ~ 180 parts of brown sugar in pieces, 100 ~ 145 parts of lemon, 2 ~ 5 parts of dried orange peel, 8 ~ 14 parts of tag processed, 20 ~ 40 parts of ramulus cinnamomi, Radix Paeoniae Alba 30 ~ 50
Part, 12 ~ 18 parts of rhizoma zingiberis, 15 ~ 25 parts of radix glycyrrhizae preparata, 20 ~ 35 parts of jujube, 12 ~ 18 parts of Rhizoma Atractylodis Macrocephalae, 18 ~ 30 parts of radix bupleuri, 7 ~ 16 parts of Fructus Aurantii,
10 ~ 20 parts and 6 ~ 15 parts of charred FRUCTUS CRATAEGI of Cortex Magnoliae Officinalis.
2. treating the lemon preserved with orange peel cream of chronic functional constipation according to claim 1, which is characterized in that further include water solubility
80 ~ 90 parts and 18 ~ 25 parts of xylo-oligosaccharide of dietary fiber.
3. treating the lemon preserved with orange peel cream of chronic functional constipation according to claim 2, which is characterized in that the water solubility meals
Food fiber is any one or a few in pectin, soyabean oligosaccharides, agar powder and carboxymethyl cellulose.
4. treating the lemon preserved with orange peel cream of chronic functional constipation according to claim 2, which is characterized in that by following parts by weight
Several each raw material composition: 150 parts of brown sugar in pieces, 125 parts of organic yellow lemon, 2.5 parts of dried orange peel, 10 parts of tag processed, 30 parts of ramulus cinnamomi, Radix Paeoniae Alba
40 parts, 15 parts of rhizoma zingiberis, 20 parts of radix glycyrrhizae preparata, 30 parts of jujube, 15 parts of Rhizoma Atractylodis Macrocephalae, 20 parts of radix bupleuri, 10 parts of Fructus Aurantii, 15 parts of Cortex Magnoliae Officinalis, charred FRUCTUS CRATAEGI
10 parts, 84 parts of water-soluble dietary fiber and 21 parts of xylo-oligosaccharide.
5. the preparation method of the lemon preserved with orange peel cream such as any one of the claim 2 ~ 4 treatment chronic functional constipation, feature
It is, comprising the following steps:
1) tag, ramulus cinnamomi, Radix Paeoniae Alba, rhizoma zingiberis, radix glycyrrhizae preparata, jujube, Rhizoma Atractylodis Macrocephalae, radix bupleuri, Fructus Aurantii, Cortex Magnoliae Officinalis and charred FRUCTUS CRATAEGI processed are weighed and obtains medicine
Then 4 ~ 6 times of water of the quality of medicinal material is added in material, impregnate 0.5 ~ 1h, be heated to boiling, 1 ~ 2h of continuous heating filters out medicine
Liquid is spare；The water that 4 ~ 6 times of the quality of medicinal material is added into the dregs of a decoction, is heated to boiling, and it is standby to filter out medical fluid by 1 ~ 2h of continuous heating
With；
2) medical fluid for obtaining step 1) merges, and staticly settles 10 ~ 24 hours, its whole supernatant is taken, then by the supernatant
Liquid is heated to boiling, and 2 ~ 3h of continuous heating obtains ointment；
3) lemon is cleaned up with salt water, then is sliced after being impregnated with physiological saline and removes seed；Dried orange peel is chopped into fourth；It will
Brown sugar in pieces grinds；Then the layering of rock sugar, lemon and dried orange peel is put into cup, then the cup is placed in stewing out of water 20 in boiling water bath
~ 28h, obtains medicinal extract；
4) ointment by step 2 preparation is added in the leachate of step 3), stirs evenly, and continues 4 ~ 6h of stewing out of water, and reaction terminates
The cup is taken out afterwards, naturally cools to 30 ~ 35 DEG C, is then added water-soluble dietary fiber and xylo-oligosaccharide, stirs evenly,
3 ~ 4h of natural cooling to get arrive the lemon preserved with orange peel cream.
6. treating the preparation method of the lemon preserved with orange peel cream of chronic functional constipation according to claim 5, which is characterized in that step
It is rapid 2) described in ointment density be 1.2.
7. treating the preparation method of the lemon preserved with orange peel cream of chronic functional constipation according to claim 5, which is characterized in that institute
Stating continuous heating temperature is 120 ~ 150 DEG C.
8. treating the preparation method of the lemon preserved with orange peel cream of chronic functional constipation according to claim 5, which is characterized in that step
Rapid 1) the described medicinal material, which also needs to be baked to be subsequently placed in front of immersion to carry out crushing at -10 ~ -30 DEG C, is made Ultramicro-powder, described
The granularity of Ultramicro-powder is 300 ~ 450 mesh.
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