CN110339231A - A kind of Chinese medicine composition and preparation method thereof for treating allergic dermatitis - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating allergic dermatitis Download PDFInfo
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Abstract
The invention belongs to technical field of traditional Chinese medicines more particularly to a kind of Chinese medicine compositions and preparation method thereof for treating allergic dermatitis.The Chinese medicine composition comprises the following components in parts by weight: 5~25 parts of honeysuckle, 5~25 parts of peppermint, 5~35 parts of Radix Glycyrrhizae, 5~35 parts of kuh-seng, 5~30 parts of Herba Andrographitis.Five medicine of Chinese medicine composition of the present invention is the same as use, altogether long memorial wind is antipruritic, detumescence of unstinging, it is clearing heat and detoxicating the benefits of, there is good therapeutic effect for various red and swollen heat fash of itching, it is significant in efficacy to contact dermatitis, allergic dermatitis, berloque dermatitis, acne rosacea and the postoperative red and swollen heat pain of laser therapy.Result of study is shown, is treated allergic dermatitis with the traditional chinese medicine composition of the invention, can be improved clinical symptoms and sign rapidly, shortens treatment time, safe and reliable.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines more particularly to a kind of Chinese medicine composition for treating allergic dermatitis and its preparations
Method.
Background technique
Allergic dermatitis is a major class illness in skin disease, and symptom can have redness, itch, pain, especially the most obvious with itch.It crosses
The pathogenic factor of quick property dermatitis includes inherent and external factor, and the allergic constitution of patient itself is the inherence that allergic dermatitis occurs
Factor can induce or aggravate allergic dermatitis disease along with stress, insomnia, over fatigue, endocrine function imbalance etc.
Feelings.The external factor for causing allergic dermatitis to be fallen ill mainly has diet, inhalation (inhalatio), weather, contact allergy object factor etc..It is wherein extra large
Fresh, spicy food, wine, sucking pollen, dust mite, cold snap, contact chemical substance, soap, detergent etc. are allergic dermatitises
The most common inducement.Due to so complexity, so that allergic dermatitis interweaves because of numerous pathogenic factors and risk factor
Recurrent exerbation together.
Currently, allergic dermatitis is treated based on oral western medicine, smearing hormone ointment or Chinese medicine treatment, oral western medicine,
It is on the one hand palliative to smear hormone ointment, cannot eradicate, another aspect side effect is big, and Chinese medicine in the prior art is controlled
The problem of that there are the courses of disease is long for treatment, weak curative effect.
Summary of the invention
The purpose of the present invention is in the prior art treatment allergic dermatitis there are the problem of, provide one kind by pure day
Right traditional Chinese medicine at Chinese medicine composition significant in efficacy, easy to use, when use is tuned into paste with cold water and is externally applied to affected part
, easy to use.Chinese medicine composition of the present invention has good therapeutic effect for various red and swollen heat fash of itching, to contact skin
Inflammation, allergic dermatitis, berloque dermatitis, acne rosacea and the postoperative dermatitis of laser therapy, it is significant in efficacy.
To achieve the above object, the present invention adopts the following technical scheme:
A kind of Chinese medicine composition for treating allergic dermatitis, comprises the following components in parts by weight: 5~25 parts of honeysuckle, thin
5~25 parts of lotus, 5~35 parts of Radix Glycyrrhizae, 5~35 parts of kuh-seng, 5~30 parts of Herba Andrographitis.
Preferably, the Chinese medicine composition of the treatment allergic dermatitis comprises the following components in parts by weight: honeysuckle 5
Part, 5 parts of peppermint, 5 parts of Radix Glycyrrhizae, 5 parts of kuh-seng, 5 parts of Herba Andrographitis.
Preferably, the Chinese medicine composition of the treatment allergic dermatitis comprises the following components in parts by weight: honeysuckle
15 parts, 15 parts of peppermint, 15 parts of Radix Glycyrrhizae, 15 parts of kuh-seng, 20 parts of Herba Andrographitis.
Preferably, the Chinese medicine composition of the treatment allergic dermatitis comprises the following components in parts by weight: honeysuckle
25 parts, 25 parts of peppermint, 35 parts of Radix Glycyrrhizae, 35 parts of kuh-seng, 30 parts of Herba Andrographitis.
Preferably, the Chinese medicine composition of the treatment allergic dermatitis comprises the following components in parts by weight: honeysuckle 8
Part, 12 parts of peppermint, 20 parts of Radix Glycyrrhizae, 18 parts of kuh-seng, 20 parts of Herba Andrographitis
Preferably, the Chinese medicine composition can be made into ointment powder.
Preferably, further including gypsum powder in the Chinese medicine composition.
Preferably, the Chinese medicine composition of the treatment allergic dermatitis, comprises the following components in parts by weight: honeysuckle
5~25 parts, 5~25 parts of peppermint, 5~35 parts of Radix Glycyrrhizae, 5~35 parts of kuh-seng, 5~30 parts of Herba Andrographitis, 500 parts of gypsum powder.
The preparation method of the Chinese medicine composition ointment of above-mentioned treatment allergic dermatitis, comprising the following steps:
(1) honeysuckle, peppermint, Radix Glycyrrhizae, kuh-seng, Herba Andrographitis are selected according to the weight ratio, are chosen except impurity；
(2) raw material after cleaning obtained by step 1 is dried under 40~80 DEG C of environment, ultraviolet radiation disinfection；
(3) step 2 gained raw material are crushed to the coarse granule of 50~150 mesh, sieving for standby with pulverizer；
(4) gypsum powder of the medicinal powder of filtering obtained by step 3 and 50~150 mesh is mixed, after mixing evenly.
Obtained Chinese medicine composition ointment powder, when use, are tuned into paste with cold water and are externally applied to affected part, user
Just.
Beneficial effect
The present invention provides a kind of Chinese medicine compositions significant in efficacy, easy to use being configured to by natural Chinese traditional medicines, make
Used time is tuned into paste with cold water and is externally applied to affected part, easy to use.Chinese medicine composition of the present invention is for various rednesses
Heat fash of itching has good therapeutic effect, to contact dermatitis, allergic dermatitis, berloque dermatitis, acne rosacea and laser therapy
Postoperative dermatitis, it is significant in efficacy.
In the Chinese medicine composition for the treatment of allergic dermatitis of the present invention, kuh-seng is bitter, trembles with fear, return heart, liver, stomach, large intestine channel can
Heat-clearing and damp-drying drug, desinsection is antipruritic, is monarch drug in a prescription；Honeysuckle is sweet, trembles with fear, and return lung, the heart, stomach, large intestine channel are clearing heat and detoxicating, is ministerial drug；Peppermint
Pungent, cool, return lung, Liver Channel have the benefits of dispelling wind and heat from the body, poison is antipruritic thoroughly, are adjutant；Radix Glycyrrhizae sweet and neutral, return 12 warps are clearing heat and detoxicating, only
Itch analgesic, coordinating the drug actions of a prescription, to make medicine；Herba Andrographitis is distributed in lung channel, and external application can be clearing heat and detoxicating, repellent antipruritic.Five medicines are the same as use, total long memorial wind
Antipruritic, detumescence of unstinging, it is clearing heat and detoxicating the benefits of.Clinical observation shows that Chinese medicine composition of the present invention has significant anti-inflammatory, anti-mistake
Quick effect, can especially alleviate rapidly patient burn, the symptom of itch, can be mitigated using rear sense of discomfort for the first time.Result of study is aobvious
Show, treat allergic dermatitis with the traditional chinese medicine composition of the invention, clinical symptoms and sign can be improved rapidly, shorten treatment time,
It is safe and reliable.
Specific embodiment
Below in conjunction with the specific embodiment of the invention, technical solution of the present invention is clearly and completely described, is shown
So, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the reality in the present invention
Example is applied, every other embodiment obtained by those of ordinary skill in the art without making creative efforts all belongs to
In the scope of protection of the invention.
Embodiment 1
A kind of Chinese medicine composition for treating allergic dermatitis, comprises the following components in parts by weight: 15 parts of honeysuckle, peppermint 15
Part, 15 parts of Radix Glycyrrhizae, 15 parts of kuh-seng, 20 parts of Herba Andrographitis.
The Chinese medicine composition can be made into ointment powder, further include gypsum powder in the Chinese medicine composition.
The Chinese medicine composition ointment powder of the treatment allergic dermatitis, comprises the following components in parts by weight: honeysuckle 15
Part, 15 parts of peppermint, 15 parts of Radix Glycyrrhizae, 15 parts of kuh-seng, 20 parts of Herba Andrographitis, 500 parts of gypsum powder.
The preparation method of above-mentioned ointment powder, comprising the following steps:
(1) honeysuckle, peppermint, Radix Glycyrrhizae, kuh-seng, Herba Andrographitis are selected according to the weight ratio, are chosen except impurity；
(2) raw material after cleaning obtained by step 1 is dried under 40 DEG C of environment, ultraviolet radiation disinfection；
(3) step 2 gained raw material are crushed to the coarse granule of 50 mesh, sieving for standby with pulverizer；
(4) gypsum powder of the medicinal powder of filtering obtained by step 3 and 50 mesh is mixed, obtains Chinese medicine freezing mask after mixing evenly.
Obtained Chinese medicine composition ointment powder, when use, are tuned into paste with cold water and are externally applied to affected part, user
Just.
Embodiment 2
A kind of Chinese medicine composition ointment powder for treating allergic dermatitis, comprises the following components in parts by weight: 5 parts of honeysuckle,
5 parts of peppermint, 5 parts of Radix Glycyrrhizae, 5 parts of kuh-seng, 5 parts of Herba Andrographitis, 500 parts of gypsum powder.
The preparation method of the Chinese medicine composition ointment powder of above-mentioned treatment allergic dermatitis, comprising the following steps:
(1) honeysuckle, peppermint, Radix Glycyrrhizae, kuh-seng, Herba Andrographitis are selected according to the weight ratio, are chosen except impurity；
(2) raw material after cleaning obtained by step 1 is dried under 60 DEG C of environment, ultraviolet radiation disinfection；
(3) step 2 gained raw material are crushed to the coarse granule of 100 mesh, sieving for standby with pulverizer；
(4) gypsum powder of the medicinal powder of filtering obtained by step 3 and 100 mesh is mixed, obtains Chinese medicine freezing mask after mixing evenly.
Obtained Chinese medicine composition ointment powder, when use, are tuned into paste with cold water and are externally applied to affected part, user
Just.
Embodiment 3
A kind of Chinese medicine composition for treating allergic dermatitis, comprises the following components in parts by weight:
25 parts of honeysuckle, 25 parts of peppermint, 35 parts of Radix Glycyrrhizae, 35 parts of kuh-seng, 30 parts of Herba Andrographitis.
The Chinese medicine composition can be made into ointment powder, further include gypsum powder in the Chinese medicine composition.
The Chinese medicine composition ointment powder, comprises the following components in parts by weight: 25 parts of honeysuckle, 25 parts of peppermint, and Radix Glycyrrhizae
35 parts, 35 parts of kuh-seng, 30 parts of Herba Andrographitis, 500 parts of gypsum powder.
The preparation method of above-mentioned ointment powder, comprising the following steps:
(1) honeysuckle, peppermint, Radix Glycyrrhizae, kuh-seng, Herba Andrographitis are selected according to the weight ratio, are chosen except impurity；
(2) raw material after cleaning obtained by step 1 is dried under 80 DEG C of environment, ultraviolet radiation disinfection；
(3) step 2 gained raw material are crushed to the coarse granule of 150 mesh, sieving for standby with pulverizer；
(4) gypsum powder of the medicinal powder of filtering obtained by step 3 and 150 mesh is mixed, obtains Chinese medicine freezing mask after mixing evenly.
Obtained Chinese medicine composition ointment powder, when use, are tuned into paste with cold water and are externally applied to affected part, user
Just.
Embodiment 4
A kind of Chinese medicine composition ointment powder for treating allergic dermatitis, comprises the following components in parts by weight: 8 parts of honeysuckle,
12 parts of peppermint, 20 parts of Radix Glycyrrhizae, 18 parts of kuh-seng, 20 parts of Herba Andrographitis, 500 parts of gypsum powder.
The preparation method of above-mentioned Chinese medicine composition ointment powder, comprising the following steps:
(1) honeysuckle, peppermint, Radix Glycyrrhizae, kuh-seng, Herba Andrographitis are selected according to the weight ratio, are chosen except impurity；
(2) raw material after cleaning obtained by step 1 is dried under 60 DEG C of environment, ultraviolet radiation disinfection；
(3) step 2 gained raw material are crushed to the coarse granule of 100 mesh, sieving for standby with pulverizer；
(4) gypsum powder of the medicinal powder of filtering obtained by step 3 and 100 mesh is mixed, obtains Chinese medicine freezing mask after mixing evenly.
Obtained Chinese medicine composition ointment powder, when use, are tuned into paste with cold water and are externally applied to affected part, user
Just.
The above are the preferable embodiments of the present invention, and those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula is changed and is modified, and therefore, the invention is not limited to above-mentioned specific embodiment, all those skilled in the art exist
Made any conspicuous improvement, replacement or modification all belong to the scope of protection of the present invention on the basis of the present invention.
Clinical test
Through clinical test, the Chinese medicine composition for the treatment of allergic dermatitis of the present invention clinically achieves extraordinary
Beneficial effect, related testing data are as follows:
Test objective: the clinical efficacy of traditional Chinese medicine composition for treating allergic dermatitis of the present invention is observed.
Case selection: 70 atopic dermatitis patients that selection Haikou kindness Dermatology Outpatient Department portion is accepted for medical treatment, according to random number
Word table method is randomly divided into treatment group and control group.Treatment group 36, male 10, female 26, the age 21~55 years old；Course of disease < 1
Moon person 20, > 1 month person 16.Control group 34, male 12, female 22；Age 25~51 years old；1 month person 18 of course of disease <
Example, > 1 month person 16.Two groups of patient's general information comparisons, difference is not statistically significant (P > 0.05), is comparable.
Diagnostic criteria: meeting the diagnostic criteria of allergic dermatitis clinical manifestation and parting, that is, have specific allergies and
Typical clinical symptoms: 1. epidermis and corium are thinning.2. hypopigmentation and pigmentation.3. exposed vessel.4. schlempe sample and Cuo
Sore sample dermatitis.5. epifolliculitis.6. hormone dependant and rebound phenomenon.Syndrome Types of TCM: 1. blood-heat type, rash is red, constipation, the red rapid pulse of tongue.
2. damp-heat type, rash flush just stick greasy, the greasy slippery of tongue fur.
Test method: control group gives commercially available conventional face mask of traditional Chinese medicine and applies face 30min, strikes off medicine film, and cold water is cleaned；Treatment group
Using 4 gained Chinese medicine composition ointment powder of the embodiment of the present invention, paste is tuned into cold water and applies face 30min, strikes off medicine film, cold water
It cleans；Two groups, no longer with any drug and other therapies, determine curative effect after treating 15d.
Curative effect determinate standard:
Cure: inflammation and fash subside completely after 15d, and skin aging significantly improves, and the senses of discomfort such as cusalgia or itch are basic
It disappears.
Effective: inflammation and deflorescence and skin aging improve degree >=60% after 15d, the senses of discomfort such as cusalgia or itch
It is obvious to disappear.
Invalid: inflammation and deflorescence and skin aging improve the equal < 60% of degree after treatment 15d, and cusalgia or itch etc. are no
The unobvious or individual event of suitable sense recession is not significant.
Test result:
By statistical procedures, two groups of Comparison of therapeutic are shown in Table 1.Clinical symptoms and the comparison of sign regression time are shown in after two groups of treatments
Table 2.
1 two groups of Comparison of therapeutic of table
| Group | Number of cases | It cures | Effectively | In vain | Effective percentage/% |
| Treatment group | 36 | 25 | 6 | 5 | 86.11 |
| Control group | 34 | 10 | 4 | 20 | 41.18 |
Two groups of comparisons, difference are statistically significant (P < 0.01).
Clinical symptoms and the comparison of sign regression time after 2 two groups of treatments of table
Note: it is compared with after control group treatment, ##P < 0.01.
Conclusion (of pressure testing): clinical observation shows that Chinese medicine composition of the present invention has significant anti-inflammatory, anti-allergic effects, especially
It can alleviate rapidly patient burn, the symptom of itch, can be mitigated using rear sense of discomfort for the first time.The display of this result of study, is used
Traditional Chinese medicine composition for treating allergic dermatitis of the present invention can improve rapidly clinical symptoms and sign, shorten treatment time, use
Securely and reliably.Traditional Chinese medicine composition for treating allergic dermatitis of the present invention is curative for effect.
In the Chinese medicine composition for the treatment of allergic dermatitis of the present invention, kuh-seng is bitter, trembles with fear, return heart, liver, stomach, large intestine channel can
Heat-clearing and damp-drying drug, desinsection is antipruritic, is monarch drug in a prescription；Honeysuckle is sweet, trembles with fear, and return lung, the heart, stomach, large intestine channel are clearing heat and detoxicating, is ministerial drug；Peppermint
Pungent, cool, return lung, Liver Channel have the benefits of dispelling wind and heat from the body, poison is antipruritic thoroughly, are adjutant；Radix Glycyrrhizae sweet and neutral, return 12 warps are clearing heat and detoxicating, only
Itch analgesic, coordinating the drug actions of a prescription, to make medicine；Herba Andrographitis is distributed in lung channel, and external application can be clearing heat and detoxicating, repellent antipruritic.Five medicines are the same as use, total long memorial wind
Antipruritic, detumescence of unstinging, it is clearing heat and detoxicating the benefits of.
Claims (9)
1. a kind of Chinese medicine composition for treating allergic dermatitis, which is characterized in that comprise the following components in parts by weight: honeysuckle 5
~25 parts, 5~25 parts of peppermint, 5~35 parts of Radix Glycyrrhizae, 5~35 parts of kuh-seng, 5~30 parts of Herba Andrographitis.
2. the Chinese medicine composition for the treatment of allergic dermatitis according to claim 1, which is characterized in that including following parts by weight
Component: 5 parts of honeysuckle, 5 parts of peppermint, 5 parts of Radix Glycyrrhizae, 5 parts of kuh-seng, 5 parts of Herba Andrographitis.
3. the Chinese medicine composition for the treatment of allergic dermatitis according to claim 1, which is characterized in that including following parts by weight
Component: 15 parts of honeysuckle, 15 parts of peppermint, 15 parts of Radix Glycyrrhizae, 15 parts of kuh-seng, 20 parts of Herba Andrographitis.
4. the Chinese medicine composition for the treatment of allergic dermatitis according to claim 1, which is characterized in that including following parts by weight
Component: 25 parts of honeysuckle, 25 parts of peppermint, 35 parts of Radix Glycyrrhizae, 35 parts of kuh-seng, 30 parts of Herba Andrographitis.
5. the Chinese medicine composition for the treatment of allergic dermatitis according to claim 1, which is characterized in that including following parts by weight
Component: 8 parts of honeysuckle, 12 parts of peppermint, 20 parts of Radix Glycyrrhizae, 18 parts of kuh-seng, 20 parts of Herba Andrographitis.
6. the Chinese medicine composition of any treatment allergic dermatitis according to claim 1~5, which is characterized in that described
Chinese medicine composition can be made into ointment.
7. the Chinese medicine composition for the treatment of allergic dermatitis according to claim 6, which is characterized in that the Chinese traditional medicine composition
It further include gypsum powder in object.
8. the Chinese medicine composition for the treatment of allergic dermatitis according to claim 7, which is characterized in that including following parts by weight
Component: 5~25 parts of honeysuckle, 5~25 parts of peppermint, 5~35 parts of Radix Glycyrrhizae, 5~35 parts of kuh-seng, 5~30 parts of Herba Andrographitis, gypsum
500 parts of powder.
9. the preparation method of the Chinese medicine composition of the treatment allergic dermatitis as described in claim 6~8 is any, feature exist
In, comprising the following steps:
(1) honeysuckle, peppermint, Radix Glycyrrhizae, kuh-seng, Herba Andrographitis are selected according to the weight ratio, are chosen except impurity；
(2) raw material after cleaning obtained by step 1 is dried under 40~80 DEG C of environment, ultraviolet radiation disinfection；
(3) step 2 gained raw material are crushed to the coarse granule of 50~150 mesh, sieving for standby with pulverizer；
(4) gypsum powder of the medicinal powder of filtering obtained by step 3 and 50~150 mesh is mixed, after mixing evenly.
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| CN113082083A (en) * | 2021-04-26 | 2021-07-09 | 杭州仁德医药有限公司 | Easily-torn traditional Chinese medicine ointment patch for allergic dermatitis and preparation method thereof |
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Address after: 570208 3rd floor, Sanpu, Jinghai garden, Haidian Sandong Road, Meilan District, Haikou City, Hainan Province Patentee after: Nanhai Renshu International Skin Hospital (Hainan) Co.,Ltd. Address before: 570208 3rd floor, Sanpu, Jinghai garden, Haidian Sandong Road, Meilan District, Haikou City, Hainan Province Patentee before: Haikou Renshu dermatology clinic Co.,Ltd. |
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