CN110339154A - A kind of anal canal indwelling suppository - Google Patents

A kind of anal canal indwelling suppository Download PDF

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Publication number
CN110339154A
CN110339154A CN201910643347.0A CN201910643347A CN110339154A CN 110339154 A CN110339154 A CN 110339154A CN 201910643347 A CN201910643347 A CN 201910643347A CN 110339154 A CN110339154 A CN 110339154A
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China
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skeleton
stype
anal canal
fixed part
indwelling
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CN201910643347.0A
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翁跃勤
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Individual
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Individual
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Priority to CN201910643347.0A priority Critical patent/CN110339154A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • A61K9/025Suppositories; Bougies; Bases therefor; Ovules characterised by shape or structure, e.g. hollow layered, coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)

Abstract

The present invention relates to a kind of anal canal indwelling suppositorys, including external fixed part, stype skeleton and medicine layer, the stype skeleton is in above the external fixed part and connect with the external fixed part, and the medicine layer is wrapped on the stype skeleton and/or is scattered in the stype skeleton and/or is attached in the stype skeleton.Compared with the stype and technology that are currently used for treatment anorectal disease, the present invention by made of medical material and carry drug stype skeleton be fixed in surgery anal canal or be fixed in surgery anal canal and rectum in, it can prevent from tissue incarceration caused by related organization's tenesmus and blood vessels from becoming silted up to hinder, can ensure that drug comes into full contact with the lesion in surgery anal canal.Can also be improved on the basis of the technical program, can cleaning surgical anal canal, exhaust gas in enteron aisle can be discharged, can be postoperative patient voluntarily dressing provide convenience, can reduce stype skeleton during indwelling give anal sphincter elasticity bring influence.

Description

A kind of anal canal indwelling suppository
Technical field
The present invention relates to field of medical article technology, specifically, in particular to a kind of anal canal indwelling suppository.
Background technique
Currently, the stype for treating the anorectal diseases such as internal piles, mixed hemorrhoid, anal canal phlegmasia is more, with the technology of the present invention feature Mainly having relatively has popularized the Suppository for treatment of pile used and number of patent application now as a kind of novel of CN96239493.9 Medical suppository.Having popularized the Suppository for treatment of pile used is characterized in that it is made of drug and appropriate substrate now, for drop rectum with drug Solid pharmaceutical preparation, it is filled in into rectum from anus when use, Suppository for treatment of pile is melted or dissolved in rectum, and drug is released in rectum It puts;Its advantage is that: easy to produce, storage and use;The disadvantage is that: it can not prevent linked groups are sagging from leading to linked groups outside Incarceration is formed in scientific anal canal and at anus and blood vessels become silted up and hinder, and its position that releases the drug is only to lead to drug and surgery in rectum Part lesion in anal canal cannot contact or insufficient contact, cannot remove dirt and soiling solution in surgery anal canal, cannot make Exhaust gas Self-discharged anus in enteron aisle cannot provide conveniently for patient with operation dressing.And application No. is CN96239493.9's That a kind of Medical suppository, purposes are for treating disease in intravaginal or anus that the purpose is to materials is few, manufacture craft is simple Single, at low cost, drug can play one's part to the full, not generate pollution, be easy to use, it is characterized in that by tampon core, bracing wire and bolt Agent-drug containing carrier matrix is constituted, and there is bracing wire in one end system of tampon core, and another section of surrounding Cheng Mo of tampon core has suppository -- drug containing Carrier matrix, for it is used to treat anorectal disease, its advantage is that: materials are few, manufacture craft is simple, at low cost, drug energy It plays one's part to the full, does not generate pollution, is easy to use;Due to its shape, construction feature and surgery anal canal and the physiology at both ends Structure feature does not match that, the tampon core with medicine layer cannot be fixed in surgery anal canal, can only be plunged into rectum Inside play a role, thus its disadvantage with to have popularized the Suppository for treatment of pile that uses now essentially identical.
It is currently used for treating deficiency present in the suppository of anorectal disease and technology:
One, the lesion of the diseases such as internal piles, mixed hemorrhoid, anal canal phlegmasia is usually in surgery anal canal, and on surgery anal canal End is in relatively closed state, and existing stype technology cannot be such that drug discharges in surgery anal canal, drug can only be made straight Enteral release, causes the part focal contact in surgery anal canal less than drug or insufficient contact, and then lead to unsatisfactory curative effect.
Two, the tissues such as mucous membrane of rectum caused by many reasons, rectal polyp crash into surgery anal canal or surgery anal canal The tissues such as mucous membrane, polyp, internal piles are fallen to anus, and linked groups is caused to form incarceration and blood vessels in surgery anal canal and at anus It becomes silted up resistance, is on the one hand unfavorable for blood circulation, on the other hand can make exacerbation of symptoms and anal sphincter elastic webbing is adversely affected. And existing stype technology can not solve the problems, such as this.
Three, the generation of the diseases such as internal piles, mixed hemorrhoid, anal fistula, anal canal phlegmasia and development and surgery anal canal are long-term unclean close Correlation, the erosion of stool, excrement slag, rheuminess object, intestinal secretion object to surgery anal tube inwall in surgery anal canal It can lead to above-mentioned disease or aggravate disease.And existing stype and technology can not remove dirt and soiling solution in surgery anal canal.
Four, the symptoms such as sagging, incarceration, oedema, inflammation that there are linked groups can lead to the passing away blocking of enteron aisle exhaust gas, And then air pressure in enteron aisle is caused to increase, the symptoms such as sagging linked groups, incarceration, oedema and inflammation are further aggravated, can also result in Intestinal absorption pernicious gas brings harm to human health.And anus can not be discharged in enteron aisle exhaust gas by existing stype technology.
Five, the surface of a wound of the diseases surgical operation such as internal piles, mixed hemorrhoid, anal fistula is usually in surgery anal canal, and removes the surface of a wound What dirt and soiling solution were placed into clean hygiene is the main purpose of Postoperative Dressing with drug application material.And existing stype technology can not be to trouble It is convenient that person's dressing provides, and patient can only arrive the dressing of professional medical mechanism.
Summary of the invention
The present invention is directed to solve one of above-mentioned technical problem in the prior art at least to a certain extent.For this purpose, this hair A bright purpose is made of medical material and to carry the stype skeleton of drug and be fixed on surgery anal canal It is interior, prevent related organization from forming incarceration and blood vessels silt resistance, drug in surgery anal canal and at anus in surgery to reach simultaneously It learns and is discharged in anal canal and ensure the purpose that drug is fully contacted with the lesion in surgery anal canal;Another object of the present invention Be: by made of medical material and carry drug stype skeleton be fixed in surgery anal canal and rectum in, Prevent related organization from forming incarceration and blood vessels silt resistance, drug in surgery anal canal and at anus simultaneously in surgery to reach simultaneously It learns in anal canal and is discharged in rectum and ensure the purpose that drug is fully contacted with the lesion in surgery anal canal.In this technology side It is improved on the basis of case, the present invention can voluntarily remove dirt and soiling solution in surgery anal canal, can make the exhaust gas in enteron aisle Self-discharged anus, can for postoperative patient voluntarily dressing provide conveniently, can make stype skeleton flexibility filling surgery anal canal to mention High usage comfort is influenced with reducing stype skeleton during indwelling to the elastic bring of anal sphincter, and structure is simple, It is easy to produce, convenient for storage, it is easy to use.
The technical scheme to solve the above technical problems is that a kind of anal canal indwelling suppository, including it is external solid Determine portion, stype skeleton and medicine layer, the stype skeleton is in above the external fixed part and connects with the external fixed part It connects, the medicine layer is wrapped on the stype skeleton and/or is scattered in the stype skeleton and/or be attached to the stype In skeleton.
Further, the external fixed part includes bottom chuck, limit body, positive stop strip, elastic drag rope or adhesive plaster block;The bottom The radial section product of chuck is greater than the radial section product of stype skeleton lower end, and the maximum radial sectional area of the limit body is big The long axis of radial section product in stype skeleton lower end, the long axis of the positive stop strip and the stype skeleton forms 60-90 One end of the angle of degree, one end of the elastic drag rope or the adhesive plaster block is connect with stype skeleton lower end.
Further, the medicine layer includes solid-state drug layer or liquid drug layer;The solid-state drug layer is drug and bolt One of agent matrix or it is a variety of mix, at normal temperature be in solid-state, be in a liquid state after being heated to it;The liquid drug layer is One of drug and pharmaceutical carrier-matrix or it is a variety of mix, be in a liquid state at normal temperature.
Further, the stype skeleton is the first stype skeleton, and the first stype skeleton includes anal canal portion skeleton and straight Intestines skeleton, the first stype skeleton are in bar shaped, and anal canal portion skeleton is fixedly connected with rectum portion skeleton, the anus The length of the surgery anal canal of the length and different crowd of pipe portion skeleton matches, and is 3.5-4.5 centimetres.
Further, under identical hoop pressure ring border, the maximum radial sectional area of rectum portion skeleton is greater than the anal canal The maximum radial sectional area of portion's skeleton;Or rectum portion skeleton has dilatancy structure.
Further, the stype skeleton is the second stype skeleton, and the second stype skeleton is in bar shaped, second stype The length of the surgery anal canal of the length and different crowd of skeleton matches, and is 3.5-4.5 centimetres;It further include built-in fixed part, The built-in fixed part lower end is fixedly connected with the second stype skeleton upper end.
Further, the built-in fixed part is described built-in under identical hoop pressure ring border in rugby or sub warhead shape The maximum radial sectional area of fixed part is greater than the maximum radial sectional area or the built-in fixed part tool of the second stype skeleton There is dilatancy structure.
Further, the built-in fixed part maximum radial sectional area is greater than the maximum radial section of the second stype skeleton Product;It further include the first propelling piece, first propelling piece includes conduit and position-arresting disk, and the position-arresting disk is fixedly set in described lead Guan Shang;The conduit is removably sleeved on the second stype skeleton for having loaded the medicine layer and contacts described built-in Fixed part.
Further, blind hole is additionally provided in the first stype skeleton, the cecum of the blind hole is in rectum portion skeleton Interior, the open end of the blind hole axially penetrates through anal canal portion skeleton straight down and communicates with the outside world;It further include the second boosting Part, second propelling piece are mandril, and the mandril is inserted into or exits the blind hole.
Further, it is additionally provided with exhaust steam passage in the first stype skeleton, the exhaust steam passage is in a strip shape, and the exhaust gas is logical Road axially penetrates through the first stype skeleton, communicates in the upper end and rectum, lower end communicates with the outside world.
The beneficial effects of the present invention are:
1, the present invention made of medical material and will carry the fixed indwelling of stype skeleton of drug in surgery In anal canal or fixed indwelling is in tissue incarceration and blood that linked groups' tenesmus in surgery anal canal and in rectum, can be prevented caused Arteries and veins become silted up resistance, can make drug discharge in surgery anal canal or can make drug simultaneously in surgery anal canal with discharged in rectum, energy Ensure that drug is fully contacted with the lesion in surgery anal canal.
2, merging product of the present invention can be facilitated, it can be by external fixed part by the stype skeleton and built-in fixed part after indwelling Pull out anus.
3, there is the suitable medical material of adsorptivity to make stype skeleton for selection, can adsorb the dirt in surgery anal canal Object and soiling solution.
4, medicine layer, which is scattered in stype skeleton or is attached in stype skeleton, can allow medicament slow release.
5, the setting of exhaust steam passage can make exhaust gas Self-discharged anus in enteron aisle.
6, stype skeleton is made using suitable medical material and this hair is made using being suitable for externally applied drug as medicine layer Bright product, can be as substitute needed for postoperative patient dressing, and for postoperative patient, voluntarily dressing is provided conveniently.
7, there is flexible suitable medical material to make stype skeleton for selection, and the filling of stype skeleton flexibility can be made outer Scientific anal canal, can reduce stype skeleton influences to anal sphincter elasticity bring during indwelling and improves using comfortable Degree.
8, structure is simple, facilitates production, facilitates storage, is easy to use.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the anal canal indwelling suppository of the present invention about embodiment 1;
Fig. 2 is a kind of structural schematic diagram of the anal canal indwelling suppository of the present invention about embodiment 2;
Fig. 3 is the structural schematic diagram of the second propelling piece of the invention;
Fig. 4 is a kind of structural schematic diagram of the anal canal indwelling suppository of the present invention about embodiment 3;
Fig. 5 is the structural schematic diagram of the first propelling piece of the invention;
Fig. 6 is a kind of structural schematic diagram of the anal canal indwelling suppository of the present invention about embodiment 4;
Fig. 7 is the structural schematic diagram of non-woven fabrics washer of the present invention.
In attached drawing, parts list represented by the reference numerals are as follows:
1, external fixed part;
2, stype skeleton, 2.1, anal canal portion skeleton, 2.2, rectum portion skeleton, 2.3, blind hole, 2.4, load medicine cavity;
3, medicine layer, the 4, second propelling piece;
5, the first propelling piece, 5.1, conduit, 5.2, position-arresting disk;
6, built-in fixed part, 7, elastic drag rope, 8, non-woven fabrics washer.
Specific embodiment
The principle and features of the present invention will be described below with reference to the accompanying drawings, and the given examples are served only to explain the present invention, and It is non-to be used to limit the scope of the invention.
Embodiment 1:
As shown in Figure 1, a kind of anal canal indwelling suppository, including external fixed part 1, stype skeleton 2 and medicine layer 3, the medicine Pessulus frame 2 is in 1 top of external fixed part and connect with the external fixed part 1.
The external fixed part 1 is bottom chuck, and the bottom chuck is in garden plate-like;The stype skeleton 2 is the first stype bone Frame is made of anal canal portion skeleton 2.1 and rectum portion skeleton 2.2, is in straight garden bar shaped, the bottom chuck and the first stype skeleton It is formed and is integrally formed by cotton fiber compacting, rectum portion skeleton 2.2 has dilatancy structure, and cotton fiber density is greater than The cotton fiber density of anal canal portion skeleton 2.1.
Described 2-4 centimetres of bottom diameter of chuck, 3-8 millimeters of thickness;6-12 millimeters of the diameter of the first stype skeleton, length 4.5-7.5 centimetres, wherein the length of anal canal portion skeleton 2.1 is 3.5-4.5 centimetres, and the length of rectum portion skeleton 2.2 is 1-3 lis Rice.
The medicine layer 3 is solid-state drug layer, and the solid-state drug layer is mixed by drug and cocoa butter, described solid State medicine layer is immersed in the first stype skeleton and is wrapped on the first stype skeleton, the bottom chuck of the present embodiment product Above section is in straight garden bar shaped, and the upper end is arc-shaped.
When manufacture, the length of the surgery anal canal of people is within the scope of 3.5-4.5, and determination is more in 3.5-4.5 cm range The length of a anal canal portion skeleton 2.1, the present embodiment product of multiple models is made.
In use, selecting appropriate model, anus is inserted into the upper end of product of the present invention, until bottom chuck touches anus crust Skin;Bottom chuck above section is retained in anus, medicine layer 3 melts in anus, and rectum portion skeleton 2.2 is swollen in rectum It is swollen, it is stuck in the present embodiment product firmly in surgery anal canal and the both ends of surgery anal canal, the extra medicine flowed out in anus Liquid is absorbed by bottom chuck.Depending on indwelling time is as needed, generally 1-8 hours.Bottom chuck is held when need to take out by stype bone Frame 2 pulls out anus.
Embodiment 2:
As shown in Fig. 2, a kind of anal canal indwelling suppository, including external fixed part 1, stype skeleton 2 and medicine layer 3, the medicine Pessulus frame 2 is in 1 top of external fixed part and connect with the external fixed part 1.
The external fixed part 1 is bottom chuck, and the bottom chuck is in garden dish type;The stype skeleton 2 is the first stype bone Frame is made of anal canal portion skeleton 2.1 and rectum portion skeleton 2.2, is in straight garden strip, the bottom chuck and the first stype skeleton It is made and is integrally formed of non-woven cotton.
Blind hole 2.3 is additionally provided in the first stype skeleton and the bottom chuck, the blind hole 2.3 is in straight garden bar shaped, institute The cecum for stating blind hole 2.3 is in rectum portion skeleton 2.2, and the blind hole 2.3 axially penetrates through the anal canal portion straight down Skeleton 2.1 and the bottom chuck, open end communicates with the outside world.
As shown in figure 3, being additionally provided with the second propelling piece 4, second propelling piece 4 is made of medical plastic in straight garden item The mandril of shape.
It is described 2-4 centimetres of bottom diameter of chuck, 2-8 millimeters thick;Described 7-12 millimeters of first stype skeleton diameter, length 4.5- 7.5 centimetres, wherein anal canal portion skeleton 2.1 is about 3.5-4.5 centimetres, and rectum portion skeleton 2.2 is about 1-3 centimetres;The blind hole 2.3 It is 4.2-6.3 centimetres long, 3-8 millimeters of diameter;The mandril is 5-10 centimetres long, and 2-7 millimeters of diameter.
The medicine layer 3 is solid-state drug layer, and the solid-state drug layer is that drug is mixed with cocoa butter, described solid State medicine layer is immersed in the first stype skeleton and is wrapped on the first stype skeleton, and the upper end of the present embodiment product is in It is arc-shaped.
When manufacture, multiple length of anal canal portion skeleton 2.1 are determined in 3.5-4.5 cm range, it is multiple to be made The product of model.The length of the blind hole 2.3 slightly larger than the bottom chuck thickness and 2.1 length of anal canal portion skeleton it With.
In use, selecting appropriate model, mandril is inserted into blind hole 2.3, and the upper end of the present embodiment product is headed into anus, until Bottom chuck touches anus outer skin, exits mandril, and by bottom chuck above section indwelling in anus, medicine layer 3 melts in anus Melt, 2.1 collapse of anal canal portion skeleton, radial section product becomes smaller, make the present embodiment product be firmly stuck in surgery anal canal and Surgery anal canal both ends, the interior extra medical fluid flowed out of anus are absorbed by bottom chuck.Depending on indwelling time is as needed, generally 1- 8 hours.
Embodiment 3:
As shown in figure 4, a kind of anal canal indwelling suppository, including external fixed part 1, stype skeleton 2 and medicine layer 3, the medicine Pessulus frame 2 is in 1 top of external fixed part and connect with the external fixed part 1.
The external fixed part 1 is elastic drag rope 7;The stype skeleton 2 is the second stype skeleton, is in straight garden bar shaped, by Non-woven cotton is made;It further include built-in fixed part 6, the built-in fixed part 6 is in sub warhead shape, is made of medical plastic, most Big radial direction sectional area is greater than the second stype skeleton radial section product;The upper end of elastic drag rope 7 is under the second stype skeleton End is protruded into and axially penetrates through the second stype skeleton;The upper end of elastic drag rope 7 and the upper end of the second stype skeleton are protruded into built-in solid Determine to be fixedly connected in portion 6 and with built-in fixed part 6.
As shown in figure 5, being additionally provided with the first propelling piece 5, first propelling piece 5 is made of conduit 5.1 and position-arresting disk 5.2, The position-arresting disk 5.2 is fixedly set on the conduit 5.1, and first propelling piece 5 is made of medical plastic.
Built-in 6 length of fixed part is 1-3 centimetres, and maximum gauge is 9-14 millimeters, and the second stype skeleton is long Degree is 3.5-4.5 centimetres, and diameter is 6-10 millimeters, and the length of the elastic drag rope 7 is 5-25 centimetres, and the position-arresting disk 5.2 is straight 2-4 centimetres of diameter, 5.1 long 4.5-9 centimetres of the conduit, 8-12 millimeters of outer diameter, 7-11 millimeters of internal diameter, the upper end is away from the limit The length of position disk 5.2 is 3.5-4.5 centimetres.
The medicine layer 3 is liquid drug layer, and the liquid drug layer is that drug is mixed with sesame oil, beeswax, described Liquid drug layer is contained in medicine bottle.
When manufacture, multiple length of the second stype skeleton are determined, in 3.5-4.5 cm range multiple types are made Number product.
In use, selecting appropriate model, liquid drug layer is applied to around the second stype skeleton, under elastic drag rope 7 End passes through conduit 5.1 from the top of conduit 5.1, and the upper end of conduit 5.1 contacts built-in fixed part 6,5.1 boosting the present embodiment of conduit Product upper end enters anus, until position-arresting disk 5.2 touches anus outer skin, exits the first propelling piece 5, elastic drag rope 7 is straightened, The lower end of elastic drag rope 7 is fixed in anus outer skin with adhesive plaster.Depending on indwelling time is as needed, generally 1-8 hours.
Example IV:
As shown in fig. 6, a kind of anal canal indwelling suppository, including external fixed part 1, stype skeleton 2 and medicine layer 3.It is described outer Setting fixed part 1 is bottom chuck, is in garden dish type, the stype skeleton 2 is the first stype skeleton, by anal canal portion skeleton 2.1 and rectum Portion's skeleton 2.2 is constituted;The first stype skeleton is in straight garden bar shaped, and the upper end is in garden orphan shape;The bottom chuck and described first Stype skeleton is made and is integrally formed by medical grade silicon rubber.
Described 2-4 centimetres of bottom diameter of chuck, 2-6 millimeters of thickness, 7-12 millimeters of the diameter of the first stype skeleton, length 4.5-7.5 centimetres, wherein the length of anal canal portion skeleton 2.1 is 3.5-4.5 centimetres, and the length of rectum portion skeleton 2.2 is 1-3 lis Rice.
It is additionally provided in the first stype skeleton and carries medicine cavity 2.4, the load medicine cavity 2.4 is in straight garden bar shaped, along described first Stype skeleton axially arranges that the load medicine cavity 2.4 abuts the bottom chuck, the length is 4-5.5 centimetres, a diameter of 5-9 milli Rice.Multiple radial garden holes are additionally provided on 2.4 wall of load medicine cavity, the radial direction garden hole is connected to the load medicine cavity 2.4 and extraneous, institute Radial garden hole is stated to be evenly arranged around the load medicine cavity 2.4.
The medicine layer 3 is solid-state drug layer, and the solid-state drug layer is mixed by drug and cocoa butter, described solid State medicine layer is attached in the first stype skeleton, and fills up the load medicine cavity 2.4 and the radial garden hole;The solid-state medicine After nitride layer fills up the load medicine cavity 2.4 and the radial garden hole, the present embodiment product smooth in appearance.
As shown in fig. 7, above the bottom chuck and lower end of the first stype skeleton is also arranged with dismountable nonwoven Cloth washer 8.
When manufacture, multiple length of anal canal portion skeleton 2.1 are determined in 3.5-4.5 cm range, it is multiple to be made The present embodiment product of model.
In use, selecting appropriate model, anus is inserted into the present embodiment product upper end, until non-woven fabrics washer 8 touches anus Skin outdoors, by the 8 above section indwelling of non-woven fabrics washer in anus, solid-state drug layer melts in anus, the anal canal portion 2.1 collapse of skeleton, radial section product become smaller, and are stuck in the present embodiment product firmly in human surgery's anal canal and surgery Anal canal both ends, non-woven fabrics washer 8 absorb the extra medical fluid flowed out from anus.Depending on indwelling time is as needed, generally 1-8 is small When.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of anal canal indwelling suppository, it is characterised in that: including external fixed part (1), stype skeleton (2) and medicine layer (3), institute Stype skeleton (2) are stated to be in above the external fixed part (1) and connect with the external fixed part (1), the medicine layer (3) It is wrapped on the stype skeleton (2) and/or is scattered in the stype skeleton (2) and/or is attached to the stype skeleton (2) It is interior.
2. a kind of anal canal indwelling suppository according to claim 1, it is characterised in that: the external fixed part (1) includes bottom card Disk, limit body, positive stop strip, elastic drag rope (7) or adhesive plaster block;The radial section product of the bottom chuck is greater than the stype skeleton (2) the radial section product of lower end, the radial direction that the maximum radial sectional area of the limit body is greater than stype skeleton (2) lower end are cut The long axis of area, the long axis of the positive stop strip and the stype skeleton (2) forms the angle of 60-90 degree, the elastic drag rope (7) One end or one end of the adhesive plaster block connect with stype skeleton (2) lower end.
3. a kind of anal canal indwelling suppository according to claim 2, it is characterised in that: the medicine layer (3) includes solid-state drug Layer or liquid drug layer;The solid-state drug layer be one of drug and suppository base or it is a variety of mix, at normal temperature In solid-state, it is in a liquid state after being heated to it;The liquid drug layer be one of drug and pharmaceutical carrier-matrix or it is a variety of mix With form, be in a liquid state at normal temperature.
4. a kind of anal canal indwelling suppository according to claim 3, it is characterised in that: the stype skeleton (2) is the first stype Skeleton, the first stype skeleton include anal canal portion skeleton (2.1) and rectum portion skeleton (2.2), and the first stype skeleton is in Bar shaped, anal canal portion skeleton (2.1) are fixedly connected with rectum portion skeleton (2.2), the length of anal canal portion skeleton (2.1) It spends and matches with the length of the surgery anal canal of different crowd, be 3.5-4.5 centimetres.
5. a kind of anal canal indwelling suppository according to claim 4, it is characterised in that: described straight under identical hoop pressure ring border The maximum radial sectional area of intestines skeleton (2.2) is greater than the maximum radial sectional area of anal canal portion skeleton (2.1);Or it is described straight Intestines skeleton (2.2) has dilatancy structure.
6. a kind of anal canal indwelling suppository according to claim 3, it is characterised in that: the stype skeleton (2) is the second stype Skeleton, the second stype skeleton are in bar shaped, the length of the surgery anal canal of the length and different crowd of the second stype skeleton Degree matches, and is 3.5-4.5 centimetres;It further include built-in fixed part (6), built-in fixed part (6) lower end and second medicine Pessulus frame upper end is fixedly connected.
7. a kind of anal canal indwelling suppository according to claim 6, it is characterised in that: the built-in fixed part (6) is in rugby Or sub warhead shape, the maximum radial sectional area of the built-in fixed part (6) is greater than described second under identical hoop pressure ring border The maximum radial sectional area of stype skeleton or the built-in fixed part (6) have dilatancy structure.
8. a kind of anal canal indwelling suppository according to claim 7, it is characterised in that: described built-in fixed part (6) maximum radial Sectional area is greater than the maximum radial sectional area of the second stype skeleton;It further include the first propelling piece (5), first propelling piece It (5) include conduit (5.1) and position-arresting disk (5.2), the position-arresting disk (5.2) is fixedly set on the conduit (5.1);It is described to lead Pipe (5.1) is removably sleeved on the second stype skeleton for having loaded the medicine layer (3) and contacts described built-in solid Determine portion (6).
9. a kind of anal canal indwelling suppository according to claim 4, it is characterised in that: be additionally provided in the first stype skeleton blind Hole (2.3), the cecum of the blind hole (2.3) are in rectum portion skeleton (2.2), and the open end of the blind hole (2.3) is perpendicular Directly run through anal canal portion skeleton (2.1) axially downwards and communicates with the outside world;It further include the second propelling piece (4), described second helps Push piece (4) is mandril, and the mandril is inserted into or exits the blind hole (2.3).
10. a kind of anal canal indwelling suppository according to claim 4, it is characterised in that: be additionally provided in the first stype skeleton Exhaust steam passage, the exhaust steam passage is in a strip shape, and the exhaust steam passage axially penetrates through the first stype skeleton, the upper end and rectum It inside communicates, lower end communicates with the outside world.
CN201910643347.0A 2019-07-17 2019-07-17 A kind of anal canal indwelling suppository Withdrawn CN110339154A (en)

Priority Applications (1)

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CN201910643347.0A CN110339154A (en) 2019-07-17 2019-07-17 A kind of anal canal indwelling suppository

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112791299A (en) * 2021-04-15 2021-05-14 北京欣康研医药科技有限公司 Anorectal disease postoperative recovery auxiliary material

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112791299A (en) * 2021-04-15 2021-05-14 北京欣康研医药科技有限公司 Anorectal disease postoperative recovery auxiliary material

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