CN110339069A - A kind of firm medicament - Google Patents

A kind of firm medicament Download PDF

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Publication number
CN110339069A
CN110339069A CN201910754472.9A CN201910754472A CN110339069A CN 110339069 A CN110339069 A CN 110339069A CN 201910754472 A CN201910754472 A CN 201910754472A CN 110339069 A CN110339069 A CN 110339069A
Authority
CN
China
Prior art keywords
parts
firm
medicament according
superfines
methyl ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910754472.9A
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Chinese (zh)
Inventor
张紫阳
韩正华
张坤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanquan College of Xinxiang Medical University
Original Assignee
Sanquan College of Xinxiang Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanquan College of Xinxiang Medical University filed Critical Sanquan College of Xinxiang Medical University
Priority to CN201910754472.9A priority Critical patent/CN110339069A/en
Publication of CN110339069A publication Critical patent/CN110339069A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/15Compositions characterised by their physical properties
    • A61K6/19Self-expanding, e.g. for filling teeth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/30Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
    • A61K6/35Preparations for stabilising dentures in the mouth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/60Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/80Preparations for artificial teeth, for filling teeth or for capping teeth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/80Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/898Polysaccharides

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  • Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a kind of firm medicaments, including according to raw material made of following number proportion: 25-45 parts of vinyl methyl ether maleic acid inorganic salt copolymer superfines, 10-15 parts of carboxymethyl cellulose, 3-5 parts of microwax, 5-8 parts of auxiliary agent, 3-5 parts of alkyl parabens, 1-4 parts of tea polyphenols and 15-20 parts of carrier.When agent for fixing component and saliva of the invention contacts, polymer material has water-swellable and forms the property of jelly, and fill the space between artificial tooth and gum, form buffer layer, and it improves bonding force lasting between artificial tooth and gums and can be improved the safety used, the entire product that addition microwax, alkyl parabens, tea polyphenols and carrier refer in inventive formulation simultaneously can remove original smell, keep certain faint scent, have the advantages that biocidal efficacies.

Description

A kind of firm medicament
Technical field
The present invention relates to a kind of technical field of the study of denture adhesive, especially a kind of firm medicament.
Background technique
The study of denture adhesive is a kind of paste-type adhesive for assisting artificial tooth to wear, it acts on basal seat area tissue surface, is absorbed Expansion makes artificial tooth and mucous membrane of mouth close adhesion after saliva, achievees the purpose that raising denture retention and stable, to improve artificial tooth The comfort of wearing, the degree of awareness are gradually increasing.Simple general introduction the study of denture adhesive effect is as follows: 1, reduces artificial tooth pair The stimulation of gum, to effectively keep oral health;2, the study of denture adhesive are effectively hindered by artificial tooth and the more firm fitting of gum Only swill enters;3, improve the adhesiveness of artificial tooth and oral cavity, enhancing bite force etc..It is suitable for full mouth and local movements Artificial tooth.
But existing the study of denture adhesive is overweight with respect to taste, and contains zinc in main component, and zinc overdose influences peace Full property and health.
Summary of the invention
It is steady that a kind of one kind for improving safety is provided the purpose of the present invention is to solve above-mentioned the deficiencies in the prior art Gu medicament.
To achieve the goals above, a kind of firm medicament designed by the present invention, including matched according to following number Raw material: 25-45 parts of vinyl methyl ether maleic acid inorganic salt copolymer superfines, 10-15 parts of carboxymethyl cellulose, microwax 3-5 parts, 5-8 parts of auxiliary agent, 3-5 parts of alkyl parabens, 1-4 parts of tea polyphenols and 15-20 parts of carrier.
Preferably, the auxiliary agent includes plasticizer, colorant, preservative, aromatic, antimicrobial, bacteriostatic agent, removes One of smelly dose or a variety of.
Preferably, the bacteriostatic agent includes Honegsukle flower P.E, propolis, Paeonol, salt.
Preferably, the aromatic is mint extract.
Preferably, including according to raw material made of following number proportion: the inorganic salt copolymer of vinyl methyl ether maleic acid 35 parts of superfines, 12 parts of carboxymethyl cellulose, 4 parts of microwax, 6 parts of auxiliary agent, 4 parts of alkyl parabens, 3 parts of tea polyphenols And carrier 18.
Preferably, the powdered molecular amount 800000-of the inorganic salt copolymer superfines of vinyl methyl ether maleic acid 1500000。
Preferably, the inorganic salt copolymer superfines of vinyl methyl ether maleic acid impacts powder by high speed machine Broken, air-flow crushing, high speed ball mill grinding obtain.
Preferably, the carrier is one of liquid paraffin, vaseline, olive oil, soybean oil or a variety of.
Preferably, further including 1-2 parts of lysozyme.
Preferably, 2 parts of the lysozyme.
When a kind of firm medicament that the present invention obtains, agent for fixing component of the invention and saliva contact, polymer material tool There is water-swellable and form the property of jelly, and fill the space between artificial tooth and gum, forms buffer layer, and improve artificial tooth Lasting bonding force and can be improved the safety used between gums, at the same added in inventive formulation microwax, The entire product that alkyl parabens, tea polyphenols and carrier refer to can remove original smell, keep certain faint scent, tool There is the advantages of biocidal efficacies.
Specific embodiment
Innovation and creation are described further below with reference to embodiment.
Embodiment 1:
A kind of firm medicament provided in this embodiment, including according to raw material made of following number proportion: vinyl methyl ether Malaysia Inorganic 25-45 parts of the salt copolymer superfines of acid, 10-15 parts of carboxymethyl cellulose, 3-5 parts of microwax, 5-8 parts of auxiliary agent, hydroxyl 3-5 parts of benzoic acid alkyl base ester, 1-4 parts of tea polyphenols and 15-20 parts of carrier.
The firm medicament in the present embodiment, including according to raw material made of following number proportion: vinyl methyl ether 40 parts of the inorganic salt copolymer superfines of maleic acid, 12 parts of carboxymethyl cellulose, microwax 4,6 parts of auxiliary agent, hydroxybenzoic acid alkane 3.5 parts of base ester, 2 parts of tea polyphenols and carrier 18 part.
Preferably, the auxiliary agent includes plasticizer, colorant, preservative, aromatic, antimicrobial, bacteriostatic agent, removes One of smelly dose or a variety of.The auxiliary agent includes plasticizer, colorant, preservative in the present embodiment.
Preferably, the powdered molecular amount 800000- of the inorganic salt copolymer superfines of vinyl methyl ether maleic acid 1500000.The powdered molecular amount of the inorganic salt copolymer superfines of the vinyl methyl ether maleic acid in the present embodiment 1200000。
Preferably, the inorganic salt copolymer superfines of vinyl methyl ether maleic acid impacts powder by high speed machine Broken, air-flow crushing, high speed ball mill grinding obtain.
Preferably, the carrier is one of liquid paraffin, vaseline, olive oil, soybean oil or a variety of.
Embodiment 2:
A kind of firm medicament provided in this embodiment, including according to raw material made of following number proportion: vinyl methyl ether Malaysia Inorganic 35 parts of the salt copolymer superfines of acid, 12 parts of carboxymethyl cellulose, 4 parts of microwax, 6 parts of auxiliary agent, hydroxybenzoic acid alkyl 4 parts of ester, 3 parts of tea polyphenols and carrier 18.
Preferably, the auxiliary agent includes plasticizer, colorant, preservative, aromatic, antimicrobial, bacteriostatic agent, removes One of smelly dose or a variety of.The auxiliary agent includes aromatic, antimicrobial, bacteriostatic agent, deodorant in the present embodiment.
Preferably, the bacteriostatic agent includes Honegsukle flower P.E, propolis, Paeonol, salt.
Preferably, the aromatic is mint extract.
Preferably, preferably, the powdered molecular of the inorganic salt copolymer superfines of the vinyl methyl ether maleic acid Amount 800000.
Preferably, the carrier is liquid paraffin, vaseline.
Embodiment 3:
A kind of firm medicament provided in this embodiment, including according to raw material made of following number proportion: vinyl methyl ether Malaysia Inorganic 25 parts of the salt copolymer superfines of acid, 10 parts of carboxymethyl cellulose, 3 parts of microwax, 5 parts of auxiliary agent, hydroxybenzoic acid alkyl 5 parts of ester, 1 part of tea polyphenols and 15 parts of carrier.
Preferably, the auxiliary agent includes plasticizer, colorant, preservative, aromatic, antimicrobial, bacteriostatic agent, removes One of smelly dose or a variety of.Described in the present embodiment plasticizer, colorant, preservative, aromatic, antimicrobial, Bacteriostatic agent, deodorant.
Preferably, the powdered molecular amount 1500000 of the inorganic salt copolymer superfines of vinyl methyl ether maleic acid.
Preferably, the inorganic salt copolymer superfines of vinyl methyl ether maleic acid impacts powder by high speed machine Broken, air-flow crushing, high speed ball mill grinding obtain.
Preferably, the carrier is one of liquid paraffin, vaseline, olive oil, soybean oil or a variety of.
Preferably, further including 1-2 parts of lysozyme.
And lysozyme 2 described in the present embodiment part.
Embodiment 4:
A kind of firm medicament provided in this embodiment, including according to raw material made of following number proportion: vinyl methyl ether Malaysia Inorganic 45 parts of the salt copolymer superfines of acid, 15 parts of carboxymethyl cellulose, 5 parts of microwax, 8 parts of auxiliary agent, hydroxybenzoic acid alkyl 3 parts of ester, 4 parts of tea polyphenols and 20 parts of carrier.
Preferably, the auxiliary agent includes bacteriostatic agent.
Preferably, the bacteriostatic agent includes Honegsukle flower P.E, propolis, Paeonol, salt.
Preferably, the powdered molecular amount 1000000 of the inorganic salt copolymer superfines of vinyl methyl ether maleic acid.
Preferably, the inorganic salt copolymer superfines of vinyl methyl ether maleic acid impacts powder by high speed machine Broken, air-flow crushing, high speed ball mill grinding obtain.
Preferably, the carrier is liquid paraffin, olive oil, soybean oil.
Preferably, further including 1 part of lysozyme.
Embodiment 5:
A kind of firm medicament provided in this embodiment, including according to raw material made of following number proportion: vinyl methyl ether Malaysia Inorganic 42 parts of the salt copolymer superfines of acid, 11 parts of carboxymethyl cellulose, 3.5 parts of microwax, 6 parts of auxiliary agent, hydroxybenzoic acid alkane 4 parts of base ester, 2 parts of tea polyphenols and carrier 18 part.
Described in the present embodiment
Preferably, the auxiliary agent includes plasticizer, colorant, preservative, aromatic, antimicrobial, bacteriostatic agent.
Preferably, the bacteriostatic agent includes Honegsukle flower P.E, propolis, Paeonol, salt.
Preferably, the aromatic is mint extract.
Preferably, the powdered molecular amount 1300000 of the inorganic salt copolymer superfines of vinyl methyl ether maleic acid.
Preferably, the carrier is liquid paraffin, vaseline, olive oil, soybean oil.
When the agent for fixing component and water that the artificial tooth of the present embodiment uses contact, polymer material has water-swellable and is formed The property of jelly, and the space between artificial tooth and gum is filled, buffer layer is formed, and improve and hold between artificial tooth and gums Long bonding force simultaneously can be improved the safety used, at the same in inventive formulation add microwax, alkyl parabens, The entire product that tea polyphenols and carrier refer to can remove original smell, keep certain faint scent, have the advantages that biocidal efficacies.
It is verified, the present embodiment 2 is compared with existing agent for fixing, the adhesiveness and persistence of the present embodiment 2 It is longer than existing agent for fixing, secured and heavier by using the existing agent for fixing smell of discovery, and the present invention has list Single tea perfume, more smelling good, while also having biocidal efficacies.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from spirit of the invention or In the case where essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state Bright restriction, it is intended that including all changes that fall within the meaning and scope of the equivalent elements of the claims in the present invention It is interior.Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, it is possible to understand that A variety of change, modification, replacement and modification can be carried out to these embodiments in the case where not departing from the principle and spirit of the invention, The scope of the present invention is defined by the appended.

Claims (10)

1. a kind of firm medicament, which is characterized in that including according to raw material made of following number proportion: vinyl methyl ether maleic acid 25-45 parts of inorganic salt copolymer superfines, 10-15 parts of carboxymethyl cellulose, 3-5 parts of microwax, 5-8 parts of auxiliary agent, hydroxy benzenes 3-5 parts of alkyl formate, 1-4 parts of tea polyphenols and 15-20 parts of carrier.
2. a kind of firm medicament according to claim 1, which is characterized in that the auxiliary agent includes plasticizer, colorant, prevents One of rotten agent, aromatic, antimicrobial, bacteriostatic agent, deodorant are a variety of.
3. a kind of firm medicament according to claim 2, which is characterized in that the bacteriostatic agent include Honegsukle flower P.E, Propolis, Paeonol, salt.
4. a kind of firm medicament according to claim 2, which is characterized in that the aromatic is mint extract.
5. a kind of firm medicament according to claim 1 or 2 or 3 or 4, which is characterized in that including matching according to following number The raw material than made of: 35 parts of the inorganic salt copolymer superfines of vinyl methyl ether maleic acid, 12 parts of carboxymethyl cellulose, microwax 4 parts, 6 parts of auxiliary agent, 4 parts of alkyl parabens, 3 parts of tea polyphenols and carrier 18.
6. a kind of firm medicament according to claim 1 or 2 or 3 or 4, which is characterized in that the vinyl methyl ether Malaysia The powdered molecular amount 800000-1500000 of the inorganic salt copolymer superfines of acid.
7. a kind of firm medicament according to claim 1 or 2 or 3 or 4, which is characterized in that the vinyl methyl ether Malaysia The inorganic salt copolymer superfines of acid is obtained by high speed machine impact comminution, air-flow crushing, high speed ball mill grinding.
8. a kind of firm medicament according to claim 1 or 2 or 3 or 4, which is characterized in that the carrier be liquid paraffin, One of vaseline, olive oil, soybean oil are a variety of.
9. a kind of firm medicament according to claim 1 or 2 or 3 or 4, which is characterized in that further include 1-2 parts of lysozyme.
10. a kind of firm medicament according to claim 9, which is characterized in that 2 parts of the lysozyme.
CN201910754472.9A 2019-08-15 2019-08-15 A kind of firm medicament Pending CN110339069A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910754472.9A CN110339069A (en) 2019-08-15 2019-08-15 A kind of firm medicament

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Application Number Priority Date Filing Date Title
CN201910754472.9A CN110339069A (en) 2019-08-15 2019-08-15 A kind of firm medicament

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CN110339069A true CN110339069A (en) 2019-10-18

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111821498A (en) * 2020-09-04 2020-10-27 侯常刚 Graphene bacteriostatic, bactericidal and deodorant Chinese herbal medicine pad combined layer
CN112569123A (en) * 2020-12-18 2021-03-30 安徽克菱保健科技有限公司 Denture fixing paste with good low-temperature extrusion performance and matrix thereof

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Publication number Priority date Publication date Assignee Title
CN101663019A (en) * 2007-05-30 2010-03-03 荷兰联合利华有限公司 Enhanced delivery of certain fragrance components from personal care compositions
CN103153263A (en) * 2010-03-10 2013-06-12 宝洁公司 Denture adhesive compositions
CN105147527A (en) * 2015-10-10 2015-12-16 博爱新开源制药股份有限公司 Denture adhesive
CN108939079A (en) * 2018-07-30 2018-12-07 郑州兰茜生物工程有限公司 A kind of oral health agent of clearing heat and detoxicating antibacterial anti-inflammatory and preparation method thereof
US20190071521A1 (en) * 2016-03-03 2019-03-07 Boai Nky Medical Holdings Ltd. Fine and Uniform Methyl Vinyl Ether-Maleic Acid Inorganic Salt Copolymers and Their Use in Oral Care and Pharmaceutical Applications

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101663019A (en) * 2007-05-30 2010-03-03 荷兰联合利华有限公司 Enhanced delivery of certain fragrance components from personal care compositions
CN103153263A (en) * 2010-03-10 2013-06-12 宝洁公司 Denture adhesive compositions
CN105147527A (en) * 2015-10-10 2015-12-16 博爱新开源制药股份有限公司 Denture adhesive
US20190071521A1 (en) * 2016-03-03 2019-03-07 Boai Nky Medical Holdings Ltd. Fine and Uniform Methyl Vinyl Ether-Maleic Acid Inorganic Salt Copolymers and Their Use in Oral Care and Pharmaceutical Applications
CN108939079A (en) * 2018-07-30 2018-12-07 郑州兰茜生物工程有限公司 A kind of oral health agent of clearing heat and detoxicating antibacterial anti-inflammatory and preparation method thereof

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Title
韩雅珊主编: "《抗衰老漫谈 点燃生日蛋糕上的第120根蜡烛》", 北京农业大学出版社, pages: 317 - 318 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111821498A (en) * 2020-09-04 2020-10-27 侯常刚 Graphene bacteriostatic, bactericidal and deodorant Chinese herbal medicine pad combined layer
CN112569123A (en) * 2020-12-18 2021-03-30 安徽克菱保健科技有限公司 Denture fixing paste with good low-temperature extrusion performance and matrix thereof
CN112569123B (en) * 2020-12-18 2023-04-11 安徽克菱保健科技有限公司 Denture fixing paste with good low-temperature extrusion performance and matrix thereof

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Application publication date: 20191018

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