CN110338409A - It is a kind of to prevent and treat the composition and its application that women's bone amount is lost - Google Patents
It is a kind of to prevent and treat the composition and its application that women's bone amount is lost Download PDFInfo
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- CN110338409A CN110338409A CN201910711222.7A CN201910711222A CN110338409A CN 110338409 A CN110338409 A CN 110338409A CN 201910711222 A CN201910711222 A CN 201910711222A CN 110338409 A CN110338409 A CN 110338409A
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- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 description 1
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- FLDFNEBHEXLZRX-UHFFFAOYSA-N nystose Natural products OC1C(O)C(CO)OC1(CO)OCC1(OCC2(OC3C(C(O)C(O)C(CO)O3)O)C(C(O)C(CO)O2)O)C(O)C(O)C(CO)O1 FLDFNEBHEXLZRX-UHFFFAOYSA-N 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
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- 239000000199 parathyroid hormone Substances 0.000 description 1
- 229960001319 parathyroid hormone Drugs 0.000 description 1
- BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 description 1
- 208000001685 postmenopausal osteoporosis Diseases 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
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- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The present invention relates to a kind of compositions that prevention and treatment women's bone amount is lost and its application, the composition to be made of each raw material of following parts by weight: 0-200 parts of skimmed milk powder, 100-150 parts of D-Glucosamine Hydrochloride, 0-250 parts of oligofructose, 0-150 parts of orange Fruit powder, 0-150 parts of bone collagen, 5-25 parts of casein phosphopeptide, colostrum be peptide 5-30 parts basic, 0.2-1 parts of vitamine D3.It is verified, composition and health food provided by the invention, with significantly preventing and improving bring range of clinical symptom due to bone amount is lost, have the function of increasing bone density, delaying osteoporosis and promote skeletal system healthy in pregnancy period, nursing period and perimenopausal women.Composition of the present invention can be used for preparing the health food that prevention and treatment women's bone amount is lost, promotes skeletal system health, have wide range of applications, and have good economy and society effect.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of to prevent and treat the composition and its application that women's bone amount is lost.
Background technique
Skeletal system is the element of human body, and bone metabolism is the one aspect of human metabolism, bone metabolism
Final result directly results in the variation of bone amount and bone density (BMD), studies have shown that the generation of osteoporosis and the mistake of bone metabolism
It weighs closely related.The bone amount of people has a stage quicklyd increase in puberty, is hereafter slowly increased, and reaches until 30 years old or so
Peak Bone Mass, with age, bone and bone density are gradually reduced, and bone amount reduces and occurs osteoporosis to a certain extent
(postmenopausal osteoporosis, PMO).Women is by factors shadows such as gestation, lactation, menopause, diet insufficiency of intakes
It rings, bone loss is more serious, easily generation osteoporosis and fracture, therefore women prevention bone amount is lost, osteoporosis is outstanding
It is important.
Bone density refers to bone mineral content every square centimeter, and full name " bone mineral density " is the one of bone strength
A main indicator, bone mineral density loss can reflect the decrease of bone strength, and risk of bone fracture increases.Clinically usually sentenced with T value
Whether the bone density of disconnected human body is normal, the bone density of bone density obtained by the person of will test detects and 30~35 years old healthy young man
It makes comparisons.To obtain the standard difference for being higher by (+) or being lower than (-) young man.- 1 < T value < 1 indicates that bone density value is normal, -2.5
< T value < -1 indicate bone amount reduction, bone-loss；T value < -2.5 indicates osteoporosis.People's all ages and classes period in life
The content of bone calcium is different: when birth, whole body calcium content is only 25 grams, and calcium content is up to 1.2 kilograms in adult body, 30 years old left side
The bone amount of right people reaches peak in life, and bone amount loses 0.5%~1% every year on average from 50 years old, and postmenopausal women is average every
Bone amount 3%~5% is lost in annual, and women's bone loss is finally up to the 30%~40% of Peak Bone Mass.Therefore Peak Bone Mass is just
Such as it is intracorporal " bone bank " with people.The main component of bone be it is calcareous, it be prevent bone amount reduce and osteoporosis it is important
Ingredient.99% calcium is stored in bone in human body, but the calcium in skeleton constantly carries out dynamic flowing in bone and blood.
When intake calcium is high, a part is excreted extra calcium by urinating, and a part of calcium then stores up in bone.And when intake calcium
When insufficient, bone calcium can flow into blood again, and excrete from urine again.The dynamic flow process of this calcium is by vitamin D and first
The adjusting of glandular hormone by shape.Estrogen plays the role of antagonism parathyroid hormone row's calcium, when decrease in estrogen in women body
When, this antagonistic ability weakens, and then bone calcium will be flowed into more in blood, then is discharged by urine, causes female bone calcium big
Amount is lost, it is easier to which calcium deficiency is susceptible to suffer from osteoporosis.
Prevention is usually more more effective than treating, because prevention bone density loss is easier than repairing bone density.At present clinically
For treat women's calcium deficiency and osteoporosis common drug (such as anti-bone resorption medicine, Bone formation medicine, calcium agent and its regulator with
And Chinese patent drug etc.), there are medical expense height, curative effect is not satisfactory.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of composition that prevention and treatment women's bone amount is lost and its application, purports
Overcoming in the prior art clinically for treating common drug high and treatment there are medical expense of women's calcium deficiency and osteoporosis
Imitate undesirable deficiency.
The technical scheme to solve the above technical problems is that a kind of composition that prevention and treatment women's bone amount is lost,
It is made of each raw material of following parts by weight:
0-200 parts of skimmed milk powder, 100-150 parts of D-Glucosamine Hydrochloride, 0-250 parts of oligofructose, orange fruit
0-150 parts of powder, 0-150 parts of bone collagen, 5-25 parts of casein phosphopeptide, colostrum be peptide 5-30 parts basic, vitamine D3 0.2-
1 part.
Based on the above technical solution, the present invention can also do preferable selection and optimal selection further below.
Preferably, the composition that above-mentioned prevention and treatment women bone amount is lost, is made of each raw material of following parts by weight:
50-200 parts of skimmed milk powder, 125-150 parts of D-Glucosamine Hydrochloride, 150-250 parts of oligofructose, orangeade
0-50 parts of fruit powder, 100-150 parts of bone collagen, 15-25 parts of casein phosphopeptide, colostrum be peptide 20-30 parts basic, vitamine D3
0.5-1 parts.
Optimal, the composition that above-mentioned prevention and treatment women's bone amount is lost is made of each raw material of following parts by weight:
200 parts of skimmed milk powder, 150 parts of D-Glucosamine Hydrochloride, 250 parts of oligofructose, 50 parts of orange Fruit powder, bone
150 parts of collagen, 25 parts of casein phosphopeptide, 24 parts, 1 part of vitamine D3 of the basic peptide of colostrum.
In addition, the application for the composition being lost the present invention also provides above-mentioned prevention and treatment women's bone amount, mainly for the preparation of
Promote the health food of skeletal system health.
In addition, the present invention also provides a kind of health foods for promoting skeletal system health comprising a effective amount of above-mentioned
Acceptable additive on composition and bromatology.
Specifically, the health food is pulvis or granule.
Compared with prior art, the beneficial effects of the present invention are:
Verified, composition and health food provided by the invention have in pregnancy period, nursing period and perimenopausal women
Having significantly prevents and improves bring range of clinical symptom due to bone amount is lost, and has and increases bone density, delaying osteoporosis
And promote the effect of skeletal system health.Composition of the present invention can be used for preparing prevention and treatment women's bone amount and be lost, promote bone
The health food of bone system health, has wide range of applications, and has good economy and society effect.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is described in further detail, and example is served only for explaining this hair
It is bright, it is not intended to limit the scope of the present invention.
Raw material used in following embodiment is then commercial product unless otherwise noted, if the method used is without especially saying
It is bright, it is this field routine techniques.
Specifically, it is commercial product that the present invention, which is named with the basic peptide of colostrum, it is the colostrum from 72 hours after cow childbirth
A kind of just the milk basic protein peptide, the also known as basic peptide of colostrum of middle extraction, can promote the proliferation and activity of osteoblast, balance osteoclastic
The activity of cell promotes deposition of the calcium on bone by adjusting the balance of osteoblast and osteoclast, to reach anti-
Control the purpose of women's bone amount loss.
Casein phosphopeptide of the present invention be hydrolyzed using bovine casein as raw material through single enzyme or compound enzyme system, then
One kind obtained from being separated, being purified contains phosphoserine cluster, and molecular weight is the natural physiological active peptide of 2000-4000.Junket
Protein phosphatase polypeptide is a kind good Analyses of High Affinity Binding Peptides, can be with the divalent minerals such as calcium, iron, magnesium, zinc, selenium in animal small intestine condition
Ions binding prevents calcium phosphate precipitation, enhances the concentration of enteral dissolvable mine substance, to promote to be absorbed and utilized.This hair
Casein phosphopeptide in the bright composition binding transport calcium, the short-distance transport for being equivalent to calcium can protect work in small intestine
Tool, avoids calcium from being lost during circulation, promotes the absorption and utilization of calcium.
D-Glucosamine Hydrochloride described in composition of the present invention is by natural chitin extraction, is a kind of
Marine biological preparation can promote the synthesis of human body mucopolysaccharide, improve the viscosity of knuckle synovia, improve the metabolism of articular cartilage.
Oligofructose of the present invention is also known as fructooligosaccharide, is passed through in β (2-1) glycosidic bond and sucrose by fructosyl
Fructosyl combines the mixture of ketose, Nystose and sugarcane sugar generated etc..Oligofructose of the present invention is responsible for
The calcium transport being complexed under one's belt discharges absorption, referred to as " the long-distance transport protection tool " of calcium into large intestine.Oligofructose cannot
It is digested and assimilated by stomach and small intestine, it is possible to sequentially reach large intestine, generation short chain fatty acids are fermented in large intestine, in large intestine
Oligofructose can help absorption of the human body to elements such as minerals such as calcium, iron, magnesium, with dietary fiber bind metal ion
Effect；" oligofructose-minerals complex compound " is formed in stomach and intestine, after reaching large intestine, with oligofructose by Bifidobacterium
Equal microbial fermentations decompose, and also release minerals (such as calcium ion, magnesium ion) simultaneously, oligofructose is by Bifidobacterium equal part
Solution, which generates short chain fatty acids, reduces the pH value of enteron aisle, and in acidic environment, the solubility of minerals such as calcium, magnesium increase, biology
Validity is also greatly improved, and furthermore short chain fatty acids (especially butyric acid) can also stimulate conjunctival cells to grow, thus
Intestinal mucosa is improved to the absorbability of minerals.Secondly oligofructose can improve enteron aisle, caused by alleviating individual crowds because replenishing the calcium
Constipation.
Embodiment 1
A kind of composition that prevention and treatment women's bone amount is lost, is made of each raw material of following parts by weight:
200 parts of skimmed milk powder, 150 parts of D-Glucosamine Hydrochloride, 250 parts of oligofructose, 50 parts of orange Fruit powder, bone
150 parts of collagen, 25 parts of casein phosphopeptide, 24 parts, 1 part of vitamine D3 of the basic peptide of colostrum.
Embodiment 2
A kind of composition that prevention and treatment women's bone amount is lost, is made of each raw material of following parts by weight:
0 part of skimmed milk powder, 100 parts of D-Glucosamine Hydrochloride, 0 part of oligofructose, 0 part of orange Fruit powder, ossein
0 part of protein 15,5 parts of casein phosphopeptide, 5 parts, 0.2 part of vitamine D3 of the basic peptide of colostrum.
Embodiment 3
A kind of composition that prevention and treatment women's bone amount is lost, is made of each raw material of following parts by weight:
200 parts of skimmed milk powder, 150 parts of D-Glucosamine Hydrochloride, 250 parts of oligofructose, 150 parts of orange Fruit powder,
50 parts of bone collagen, 25 parts of casein phosphopeptide, 30 parts, 1 part of vitamine D3 of the basic peptide of colostrum.
Embodiment 4
A kind of composition that prevention and treatment women's bone amount is lost, is made of each raw material of following parts by weight:
150 parts of skimmed milk powder, 100 parts of D-Glucosamine Hydrochloride, 15 parts of oligofructose, 60 parts of orange Fruit powder, bone
0 part of collagen, 5 parts of casein phosphopeptide, 20 parts, 0.5 part of vitamine D3 of the basic peptide of colostrum.
Embodiment 5
A kind of composition that prevention and treatment women's bone amount is lost, is made of each raw material of following parts by weight:
50 parts of skimmed milk powder, 125 parts of D-Glucosamine Hydrochloride, 150 parts of oligofructose, 0 part of orange Fruit powder, gelatine
0 part of former protein 10,15 parts of casein phosphopeptide, 20 parts, 0.5 part of vitamine D3 of the basic peptide of colostrum
Embodiment 6
A kind of composition that prevention and treatment women's bone amount is lost, is made of each raw material of following parts by weight:
200 parts of skimmed milk powder, 150 parts of D-Glucosamine Hydrochloride, 250 parts of oligofructose, 50 parts of orange Fruit powder, bone
150 parts of collagen, 25 parts of casein phosphopeptide, 30 parts, 1 part of vitamine D3 of the basic peptide of colostrum.
The corresponding composition of the above various embodiments passes through following methods and is prepared, and specifically comprises the following steps:
1) skimmed milk powder, bone collagen, casein phosphopeptide, the basic peptide of colostrum are uniformly mixed so as to obtain according to formula rate mixed
Close object one；
2) D-Glucosamine Hydrochloride, oligofructose, orange Fruit powder, vitamine D3 are mixed according to formula rate equal
It is even to obtain mixture two；
3) mixture one and mixture two are mixed in proportion to obtain the final product.
It should be noted that can proportionally weigh each raw material respectively in advance before carrying out above-mentioned preparation, then carry out again
It is respectively step by step rapid.
Implement 1 to 6 corresponding composition respectively through 30 or more bone amount to be lost relatively heavy women respectively (age exists
Between 30-55, bone density is between -2.5 to -1 and is in pregnancy period, nursing period or climacteric) it is checked after edible half a year, it sends out
Existing bone amount wastage is clearly better, and bone density has different degrees of rise substantially, and effect is preferable.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (6)
1. a kind of composition that prevention and treatment women's bone amount is lost, which is characterized in that be made of each raw material of following parts by weight:
0-200 parts of skimmed milk powder, 100-150 parts of D-Glucosamine Hydrochloride, 0-250 parts of oligofructose, orange Fruit powder 0-
150 parts, 0-150 parts of bone collagen, 5-25 parts of casein phosphopeptide, colostrum it is peptide 5-30 parts basic, 0.2-1 parts of vitamine D3.
2. a kind of composition that prevention and treatment women's bone amount is lost according to claim 1, which is characterized in that by following parts by weight
Several each raw materials are made:
50-200 parts of skimmed milk powder, 125-150 parts of D-Glucosamine Hydrochloride, 150-250 parts of oligofructose, orange Fruit powder
0-50 parts, 100-150 parts of bone collagen, 15-25 parts of casein phosphopeptide, colostrum be peptide 20-30 parts basic, vitamine D3
0.5-1 parts.
3. a kind of composition that prevention and treatment women's bone amount is lost according to claim 2, which is characterized in that by following parts by weight
Several each raw materials are made:
200 parts of skimmed milk powder, 150 parts of D-Glucosamine Hydrochloride, 250 parts of oligofructose, 50 parts of orange Fruit powder, ossein
0 part of protein 15,25 parts of casein phosphopeptide, 24 parts, 1 part of vitamine D3 of the basic peptide of colostrum.
4. a kind of application for the composition that prevention and treatment women's bone amount as described in any one of claims 1 to 3 is lost, feature exist
In, be used to prepare promote skeletal system health health food.
5. a kind of health food for promoting skeletal system health, which is characterized in that any including a effective amount of claims 1 to 3
Acceptable additive on composition and bromatology described in.
6. a kind of health food for promoting skeletal system health according to claim 5, which is characterized in that the health care food
Product are pulvis or granule.
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| CN102106399A (en) * | 2010-12-30 | 2011-06-29 | 东莞市德亨饮料食品有限公司 | Peanut milk beverage with calcium supplementing function and preparation method thereof |
| CN103784939A (en) * | 2012-10-31 | 2014-05-14 | 天狮集团有限公司 | Composition for enhancing bone mineral density |
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| CN106235311A (en) * | 2016-07-28 | 2016-12-21 | 广州赛莱拉干细胞科技股份有限公司 | A kind of compositions promoting skeletal system health and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106399A (en) * | 2010-12-30 | 2011-06-29 | 东莞市德亨饮料食品有限公司 | Peanut milk beverage with calcium supplementing function and preparation method thereof |
| CN103784939A (en) * | 2012-10-31 | 2014-05-14 | 天狮集团有限公司 | Composition for enhancing bone mineral density |
| CN105056216A (en) * | 2015-09-23 | 2015-11-18 | 北京里肯营养科学研究有限公司 | Calcium supplementing preparation/granule and preparation method thereof |
| CN106235311A (en) * | 2016-07-28 | 2016-12-21 | 广州赛莱拉干细胞科技股份有限公司 | A kind of compositions promoting skeletal system health and application thereof |
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Application publication date: 20191018 |