CN110314208A - A kind of Chinese medicine composition and preparation method thereof preventing face acnes - Google Patents
A kind of Chinese medicine composition and preparation method thereof preventing face acnes Download PDFInfo
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Abstract
The present invention relates to technical field of traditional Chinese medicine, more particularly to a kind of Chinese medicine composition and preparation method thereof for preventing face acnes, the bulk pharmaceutical chemicals including following parts by weight: 98-103 parts of wormwood, 12-17 parts of wild chrysanthemum, 12-17 parts of dandelion, 3-7 parts of safflower, 12-17 parts of honeysuckle, 12-17 parts of viola mandshurica, 17-22 parts of adlay, 8-12 parts of Herba portulacae, 3-7 parts of gynostemma pentaphylla；Chinese medicine composition of the invention has the double effects prevented and treated for face acnes, has no toxic side effect, absorbs quick, significant effect, is nonirritant, non-sensitization, also having effects that skin whitening, moisturizing.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, and in particular to a kind of Chinese medicine composition for preventing face acnes and its
Preparation method.
Background technique
Face acnes are current clinical most commonly seen one of illnesss, and clinical manifestation is mainly concentrated as acne, papule, purulence
The skin injuries such as blister, tumour, tubercle, are common in youth of both sexes, and pathomechanism is mainly that chronic inflammation occurs for pilosebaceous follicle.
The patent No. 201610993593.5 discloses a kind of daily use chemicals for being added to natural medicinal ingredient and not being destroyed Chinese herbal medicine
Articles, wherein comprising Chinese herbal medicines such as the radix tetrastigme, wormwood, purslane, dandelion, Sculellaria barbata, the lobelia chinensis that account for total weight 2-25%
A kind of or any a variety of preliminary working objects, extract, and be that preliminary working or extraction are carried out under the conditions of controlling temperature, to keep day
Right medicinal ingredient can also control in temperature range further to keep natural medicinal ingredient in manufacture craft.Daily chemical product can
It is specific such as toothpaste, soap, facial mask for laundry detergent compositions, personal hygiene detergent, cosmetics and family daily necessity detergent etc.
Deng daily chemical product can also being replaced with certain pharmaceutical preparations.The daily chemical product that the program provides can be used for assisting in the treatment of, and use
Be very natural and facilitate, without deliberately go medication.
The patent No. 201710471341.0 discloses a kind of sterilize and is good for skin cleaning solution, is decocted by Traditional Chinese drug mixture and pure water
It is made, the dosage of the pure water is 60-90 times of Traditional Chinese drug mixture weight；The Traditional Chinese drug mixture by following parts by weight object
Matter is mixed: 10-20 parts of wormwood, 10-20 parts of sweet wormwood, and 5-10 parts of polygonum cuspidate, 5-10 parts of climbing groundsel, 5-10 parts of radix scutellariae, Cortex Phellodendri 5-
10 parts, 5-10 parts of kuh-seng, 10-20 parts of honeysuckle, 5-15 parts of purslane, 10-20 parts of dandelion and 10-20 parts of frutus cnidii, meanwhile,
Also disclose the method that skin cleaning solution is good in above-mentioned sterilization for preparing.The invention is sterilized strong skin cleaning solution and is made of decocting for Chinese herbal medicine, has
There are anti-inflammatory, sterilization, the redness suitable for the cleaning of various scytitis, especially to skin appearance after bite by mosquitos
Effect is obvious, and does not add preservative, small to the irritation of skin, and the crowd of all age group is suitble to use.
The patent No. 201811089371.6 discloses a kind of Chinese medicine bath block and preparation method, it is by sodium bicarbonate, anhydrous lemon
Acid, cornstarch, Chinese medicine, purification sea salt, distilled water, alcohol, vegetable colour, oils, essential oil class composition, step is: A, weighing
Raw material；B, by Chinese medicine grind into powder；C, hybrid solid material: by sodium bicarbonate, anhydrous citric acid, cornstarch, Chinese medicine, purification
Sea salt mixing, stirs evenly；D, distilled water, oils, essential oil, vegetable colour mixing liquid material: are mixed into suspension；
E, material is poured into container, stirring rod is stirred；F, enter mould: taking PVC moulding mould, one layer of olive oil of mold brush will mix
Uniform material press-in die is closed, is compacted；F, it demoulds: obtaining Chinese medicine bath block.Bath block has relaxing tendons and activating collaterals, warming channel and expelling cold, promoting blood circulation row
Gas, anti-inflammation and sterilization, removing dampness to relieve itching, fragrance deodorizing, softening improve water quality, releive loosen, whitening and moistening skin, antitoxic heart-soothing and sedative, improvement follow
Ring effect.
But there are skin absorption differences, being irritating to the skin property in currently available technology, and existing product is for controlling
It treats, rarely has prevention product.
Summary of the invention
The present invention is in order to solve the above technical problems, provide a kind of Chinese medicine composition for preventing face acnes and its preparation side
Method.
It is realized particular by following technical scheme:
A kind of Chinese medicine composition preventing face acnes, the bulk pharmaceutical chemicals including following parts by weight: 98-103 parts of wormwood, mother chrysanthemum
Flower 12-17 parts, 12-17 parts of dandelion, 3-7 parts of safflower, 12-17 parts of honeysuckle, 12-17 parts of viola mandshurica, 17-22 parts of adlay,
8-12 parts of Herba portulacae, 3-7 parts of gynostemma pentaphylla.
Further, the Chinese medicine composition of the prevention face acnes, the bulk pharmaceutical chemicals including following parts by weight: 100 parts of wormwood,
15 parts of wild chrysanthemum, 5 parts of safflower, 15 parts of honeysuckle, 15 parts of viola mandshurica, 20 parts of adlay, 10 parts of Herba portulacae, twists 15 parts of dandelion
Stock is 5 parts blue.
The present invention also provides the preparation methods of the Chinese medicine composition of prevention face acnes, include the following steps:
1) wormwood, gynostemma pentaphylla are extracted: refrigerating 1-2h under the conditions of taking wormwood, gynostemma pentaphylla to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, the organic acid soln of wormwood, 15-18 times of gynostemma pentaphyllum total weight is then added, is placed under Ultrasonic Conditions
30-45min is managed, after filtering, is concentrated into original volume 1/3；
2) wild chrysanthemum, safflower are extracted: refrigerating 1-2h under the conditions of taking wild chrysanthemum, safflower to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, the mineral water of wild chrysanthemum, 15-18 times of safflower total weight is then added, is placed under Ultrasonic Conditions and handles
30-45min after filtering, is concentrated into original volume 1/3；
3) dandelion, honeysuckle are extracted: refrigerating 1-2h under the conditions of taking dandelion, honeysuckle to be placed in -5~-10 DEG C, taking-up is
50 meshes can be ground to, the salt water of dandelion, 20-25 times of honeysuckle total weight is then added, is placed under Ultrasonic Conditions
30-45min is managed, after filtering, is concentrated into original volume 1/3；
4) adlay, Herba portulacae are extracted: refrigerating 1-2h under the conditions of taking adlay, Herba portulacae to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, the water containing tea polyphenols of adlay, 20-25 times of Herba portulacae total weight is then added, is placed under Ultrasonic Conditions
30-45min is handled, after filtering, is concentrated into original volume 1/3；
5) it extracts viola mandshurica: taking viola mandshurica to refrigerate 1-2h under the conditions of -5~-10 DEG C, taking-up can be ground to 50
Then the distilled water of 20-25 times of viola mandshurica weight is added in mesh, mentioned using the program mode heating mode that program mode cools down again
It takes, after filtering, is concentrated into original volume 1/3；
6) it mixed processing: after the extract of step 1) to step 5) is handled 4-8min under microwave condition, then is placed in super
3-7min is handled under the conditions of sound wave, is dried in vacuo to obtain composition.
Ultrasonic wave operating condition in the step 1) are as follows: frequency 55-65kHz.
The mass concentration of organic acid soln is 40-50% in the step 1).
Organic acid soln is tartaric acid and citric acid 1:(1-1.5 in mass ratio in the step 1)) composition.
Ultrasonic wave operating condition in the step 2) are as follows: frequency 30-35kHz.
Every liter of mineral water contains following ingredient: calcium 8-12mg, sodium 3-7mg, potassium 10-15mg, magnesium 15- in the step 2)
25mg, chlorine≤0.02mg.
Ultrasonic wave operating condition in the step 3) are as follows: frequency 60-70kHz.
The mesohalobic mass concentration of step 3) is 20-30%.
Ultrasonic wave operating condition in the step 4) are as follows: frequency 45-50kHz.
Tea polyphenols accounting is 5-10% in the water containing tea polyphenols in the step 4).
It is 30 DEG C that program mode heating, which is adjustment initial temperature, in the step 5), and outlet temperature is 90 DEG C, and heating rate is
2-3℃/min。
It is 90 DEG C that program mode cooling, which is adjustment initial temperature, in the step 5), and outlet temperature is 20 DEG C, and rate of temperature fall is
1-1.5℃/min。
The operating condition of microwave treatment in the step 6) are as follows: firm power 300-500W.
Ultrasonic wave operating condition in the step 6) are as follows: frequency 95-105kHz.
The temperature being concentrated in the step 1) to step 5) is 120-150 DEG C.
Compared with prior art, the beneficial effect of the invention is:
Wormwood: it Wen Jing, dries, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, miscarriage prevention, antiallergy.
Wild chrysanthemum: clearing heat and detoxicating, wind-dispelling heat-dissipating dissipates the stasis of blood, improving eyesight, blood pressure lowering.Prevent and treat meningococal meningitis, prevention stream
Row sexuality emits, catches a cold, and can also treat hypertension, hepatitis, dysentery, carbuncle furuncle and treat sore.
Dandelion: clearing heat and detoxicating, diuresis dissipating bind；Main treatment acute mastitis, adenolymphitis, scrofula, boil poisonous soreness are acute
Conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.
Safflower: blood circulation, removing blood stasis and acesodyne, facilitate controlling through closing, dysmenorrhea, lochia, chest impediment and cardialgia, stasis of blood,
Pricking pain in the chest, traumatic injury, sore swell and ache curative curative effect.There is the effect of activating microcirculation and removing stasis medicinal, dissipate wet effect going to swell.
Honeysuckle: clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind；Cure mainly disease under turgor, warm disease heating, heat toxin large carbuncle and tumour etc.
Disease.Can be used for dizziness, thirst, sweating and boring, enteritis, bacillary dysentery, morbilli, pneumonia, encephalitis, epidemic meningitis, acute mastitis,
The diseases such as septicemia, ecphyaditis, skin infection, ulcer boils, erysipelas, parotitis, suppurative tonsillitis.
Viola mandshurica: clearing heat and detoxicating；Cure mainly jaundice, dysentery, mazoitis, red eye, swell pain, pharyngitis；External application control traumatic injury,
Carbuncle swells, venomous snake bite.Flavonoid glycosides and organic acid contained by viola mandshurica to gold-coloured staphylococci, pig Pasteurella, Escherichia coli,
Streptococcus and salmonella have stronger bacteriostasis.
Adlay: inducing diuresis for removing edema, invigorating the spleen to clear away damp pathogen, clearing away heat and eliminating pus, anti-inflammatory and antalgic, strengthen immunity
Herba portulacae: clearing heat and promoting diuresis, anti-inflammatory, is quenched the thirst, diuresis at removing toxicity for detumescence.
Gynostemma pentaphylla: replenishing qi to invigorate the spleen, and preventing phlegm from forming and stopping coughing is clearing heat and detoxicating.
Wild chrysanthemum, dandelion, viola mandshurica, honeysuckle, Herba portulacae, gynostemma pentaphylla are clearing heat and detoxicating, and antibacterial treats sore；It is wormwood, red
Flower Wen Jing, promoting blood circulation, stagnation resolvation；Adlay clearing damp detumescence, clearing away heat and eliminating pus.All medicines share plays clearing heat and detoxicating, dehumidifying apocenosis altogether, promoting blood circulation disappears
Spot, the antibacterial function for treating sore, can use for various period face acnes.
Chinese medicine composition of the invention has the double effects prevented and treated for face acnes, has no toxic side effect, inhales
Receive quickly, significant effect, nonirritant, non-sensitization, also have effects that skin whitening, moisturizing.
The present invention by extracting bulk pharmaceutical chemicals respectively, it is ensured that the dissolution rate of effective component, by molten using difference
The means that agent and ultrasonic wave, alternating temperature extract, not only shorten extraction time, also improve the activity of effective component, and then advantageous
In cost declining, promote to absorb.
The present invention utilizes microwave treatment, has not only killed harmful microorganism, has further improved the structure of composition, not only promoted
The compatibility of composition, can be preferably compatible with the auxiliary material that pharmaceutically allows, also improves the penetrating power of composition, has
Help skin absorption.It recycles ultrasonic wave further to adjust, the stability of product is strengthened, so that assisting between effective component
Same-action has highlighted the effect of skin whitening, moisturizing.
Specific embodiment
Specific embodiments of the present invention will be described in further detail below, but the invention is not limited to these realities
Mode is applied, it is claimed to still fall within the claims in the present invention for any improvement or replacement on the present embodiment essence spirit
Range.
Embodiment 1
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 103kg, wild chrysanthemum 17kg, Pu Gong
English 17kg, safflower 7kg, honeysuckle 17kg, viola mandshurica 17kg, adlay 22kg, Herba portulacae 12kg, gynostemma pentaphylla 7kg.
Embodiment 2
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 98kg, wild chrysanthemum 12kg, Pu Gong
English 12kg, safflower 3kg, honeysuckle 12kg, viola mandshurica 12kg, adlay 17kg, Herba portulacae 8kg, gynostemma pentaphylla 3kg.
Embodiment 3
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 100kg, wild chrysanthemum 15kg, Pu Gong
English 15kg, safflower 5kg, honeysuckle 15kg, viola mandshurica 15kg, adlay 20kg, Herba portulacae 10kg, gynostemma pentaphylla 5kg.
Embodiment 4
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 98kg, wild chrysanthemum 12kg, Pu Gong
English 17kg, safflower 7kg, honeysuckle 17kg, viola mandshurica 12kg, adlay 22kg, Herba portulacae 8kg, gynostemma pentaphylla 3kg.
Embodiment 5
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 100.5kg, wild chrysanthemum 14kg, Pu
Public English 14kg, safflower 4kg, honeysuckle 14kg, viola mandshurica 14kg, adlay 19kg, Herba portulacae 10kg, gynostemma pentaphylla 5kg.
Comparative example 1
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 103.5kg, wild chrysanthemum 17.5kg,
Dandelion 17.5kg, it safflower 7.5kg, honeysuckle 17.5kg, viola mandshurica 17.5kg, adlay 22.5kg, Herba portulacae 12.5kg, twists
Stock indigo plant 7.5kg.
Comparative example 2
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 97.5kg, wild chrysanthemum 11.5kg,
Dandelion 11.5kg, it safflower 2.5kg, honeysuckle 11.5kg, viola mandshurica 11.5kg, adlay 16.5kg, Herba portulacae 7.5kg, twists
Stock indigo plant 2.5kg.
Comparative example 3
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 100kg, wild chrysanthemum 15kg, Pu Gong
English 15kg, safflower 5kg, honeysuckle 15kg, adlay 20kg, Herba portulacae 10kg, gynostemma pentaphylla 5kg.
Comparative example 4
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 100kg, wild chrysanthemum 15kg, Pu Gong
English 15kg, viola mandshurica 15kg, adlay 20kg, Herba portulacae 10kg, gynostemma pentaphylla 5kg.
Comparative example 5
A kind of Chinese medicine composition preventing face acnes, including the following raw material medicine: wormwood 100kg, wild chrysanthemum 15kg, Pu Gong
English 15kg, safflower 5kg, honeysuckle 15kg, viola mandshurica 15kg, adlay 20kg, Herba portulacae 10kg, gynostemma pentaphylla 5kg, aloe
15kg。
Embodiment 6
The present embodiment embodiment 1- embodiment 5 it is any on the basis of provide the Chinese medicine composition of prevention face acnes
Preparation method includes the following steps:
1) wormwood, gynostemma pentaphylla are extracted: refrigerating 1-2h under the conditions of taking wormwood, gynostemma pentaphylla to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, wormwood, 15-18 times of gynostemma pentaphyllum total weight, the organic acid soln that mass concentration is 40-50% is then added,
It is placed under the Ultrasonic Conditions of frequency 55-65kHz and handles 30-45min, after filtering, substance is concentrated under the conditions of 120-150 DEG C
Product 1/3；
2) wild chrysanthemum, safflower are extracted: refrigerating 1-2h under the conditions of taking wild chrysanthemum, safflower to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, the mineral water of wild chrysanthemum, 15-18 times of safflower total weight is then added, are placed in the super of frequency 30-35kHz
30-45min is handled under the conditions of sound wave, and after filtering, original volume 1/3 is concentrated under the conditions of 120-150 DEG C；Every liter of mineral water contains
There is following ingredient: calcium 8-12mg, sodium 3-7mg, potassium 10-15mg, magnesium 15-25mg, chlorine≤0.02mg；
3) dandelion, honeysuckle are extracted: refrigerating 1-2h under the conditions of taking dandelion, honeysuckle to be placed in -5~-10 DEG C, taking-up is
50 meshes can be ground to, dandelion, 20-25 times of honeysuckle total weight, the salt water that mass concentration is 20-30% is then added,
It is placed under the Ultrasonic Conditions of frequency 60-70kHz and handles 30-45min, after filtering, substance is concentrated under the conditions of 120-150 DEG C
Product 1/3；
4) adlay, Herba portulacae are extracted: refrigerating 1-2h under the conditions of taking adlay, Herba portulacae to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, the water of the tea polyphenols of 5-10% containing mass fraction of adlay, 20-25 times of Herba portulacae total weight is then added, sets
30-45min is handled under the Ultrasonic Conditions of frequency 45-50kHz, and after filtering, original volume is concentrated under the conditions of 120-150 DEG C
1/3；
5) it extracts viola mandshurica: taking viola mandshurica to refrigerate 1-2h under the conditions of -5~-10 DEG C, taking-up can be ground to 50
Then the distilled water of 20-25 times of viola mandshurica weight is added in mesh, first adjusting initial temperature is 30 DEG C, with the speed of 2-3 DEG C/min
Rate is warming up to 90 DEG C, then is cooled to 20 DEG C, after filtering with the rate of 1-1.5 DEG C/min, and original is concentrated under the conditions of 120-150 DEG C
Volume 1/3；
6) mixed processing: by the extract of step 1) to step 5) in firm power under the microwave condition of 300-500W
It after managing 4-8min, then is placed under the Ultrasonic Conditions of frequency 95-105kHz and handles 3-7min, be dried in vacuo to obtain composition；
Organic acid soln is tartaric acid and citric acid 1:(1-1.5 in mass ratio in the step 1)) composition.
Comparative example 6
Difference with embodiment 6 is: the extraction of bulk pharmaceutical chemicals is wormwood, wild chrysanthemum, dandelion, safflower, honeysuckle, pale reddish brown
Chinese violet, adlay, Herba portulacae, gynostemma pentaphylla refrigerate 1-2h under the conditions of being placed in -5~-10 DEG C, taking-up can be ground to 50 meshes, so
20-25 times of bulk pharmaceutical chemicals total weight is added afterwards, the ethanol solution that mass concentration is 75-85%, is placed in the ultrasound of frequency 30-35kHz
30-45min is handled under the conditions of wave, and original volume 1/3 is concentrated into after filtering, under the conditions of 120-150 DEG C.
Comparative example 7
Difference with embodiment 6 is: the extraction of bulk pharmaceutical chemicals does not use ultrasonic wave to assist.
Comparative example 8
Difference with embodiment 6 is: mixed processing step does not use microwave technology.
Test example 1
1. experimental material and grouping
The preparation of 1.1 Chinese medicine compositions
1.1.1 test group 1-5 is respectively prepared the formula group of embodiment 1-5 according to the method for embodiment 6；
1.1.2 control group 1-2 is respectively prepared the formula group of comparative example 1-2 according to the method for embodiment 6；
1.1.3 control group 3-5 is as follows respectively prepared the formula group of comparative example 3-5: by all raw materials
Medicine refrigerates 1-2h under the conditions of being placed in -5~-10 DEG C, taking-up can be ground to 50 meshes, and bulk pharmaceutical chemicals total weight 20- is then added
25 times, the ethanol solution that mass concentration is 75-85%, are placed under the Ultrasonic Conditions of frequency 30-35kHz and handle 30-45min,
Original volume 1/3 is concentrated into after filtering, under the conditions of 120-150 DEG C；
1.2 experimental groups: the selection age, the crowd with face acnes was test object at 15-25 years old, was randomly divided into 10
Group, every group of 10 people, each group there are no significant in terms of skin health, organism endocrine difference；
2 experimental methods: it after conditioned water for skin to be treated is cleaned, takes appropriate skin care item at the palm of the hand, slightly rubs, uniformly
It is applied to the position with face acnes.
3 experimental results:
Comprehensive score is carried out using investigation point system.Smearing skin care item are primary before every group of crowd sleeps daily, continuous to smear 3
Month, fill in grade form on probation.Every using effect total score is 10 points in grade form, and 9-10 points indicate that effect is optimal；6-8 points indicate
Effect is preferable；4-5 points indicate that effect is general；3 points of following presentation effects are poor, every using effect average situation such as table 1
It is shown:
1 each group of table and blank group comparison result (n=10)
| Anti-acne degree | Pachylosis improves degree | Skin irritatin degree of alleviation | |
| Control group 1 | 4.2 | 5.1 | 6.2 |
| Control group 2 | 5.3 | 4.8 | 6.3 |
| Control group 3 | 6.1 | 5.3 | 5.7 |
| Control group 4 | 4.5 | 5.5 | 6.1 |
| Control group 5 | 5.0 | 4.7 | 5.4 |
| Test group 1 | 8.6 | 8.5 | 9.4 |
| Test group 2 | 8.3 | 8.4 | 9.1 |
| Test group 3 | 9.0 | 8.7 | 9.5 |
| Test group 4 | 8.4 | 8.8 | 8.9 |
| Test group 5 | 8.7 | 8.6 | 8.7 |
Claims (10)
1. a kind of Chinese medicine composition for preventing face acnes, which is characterized in that the bulk pharmaceutical chemicals including following parts by weight: wormwood 98-
103 parts, 12-17 parts of wild chrysanthemum, 12-17 parts of dandelion, 3-7 parts of safflower, 12-17 parts of honeysuckle, 12-17 parts of viola mandshurica, the heart of a lotus seed
17-22 parts of benevolence, 8-12 parts of Herba portulacae, 3-7 parts of gynostemma pentaphylla.
2. the Chinese medicine composition of prevention face acnes as described in claim 1, which is characterized in that in the prevention face acnes
Drug composition, the bulk pharmaceutical chemicals including following parts by weight: 100 parts of wormwood, 15 parts of wild chrysanthemum, 15 parts of dandelion, 5 parts of safflower, gold and silver
Spend 15 parts, 15 parts of viola mandshurica, 20 parts of adlay, 10 parts of Herba portulacae, 5 parts of gynostemma pentaphylla.
3. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 1 or 2, which is characterized in that including such as
Lower step:
1) wormwood, gynostemma pentaphylla are extracted: refrigerating 1-2h under the conditions of taking wormwood, gynostemma pentaphylla to be placed in -5~-10 DEG C, taking-up can be ground to
50 meshes are crossed, the organic acid soln of wormwood, 15-18 times of gynostemma pentaphyllum total weight is then added, is placed under Ultrasonic Conditions and handles 30-
45min after filtering, is concentrated into original volume 1/3；
2) wild chrysanthemum, safflower are extracted: refrigerating 1-2h under the conditions of taking wild chrysanthemum, safflower to be placed in -5~-10 DEG C, taking-up can be ground to
50 meshes are crossed, the mineral water of wild chrysanthemum, 15-18 times of safflower total weight is then added, is placed under Ultrasonic Conditions and handles 30-
45min after filtering, is concentrated into original volume 1/3；
3) dandelion, honeysuckle are extracted: refrigerating 1-2h under the conditions of taking dandelion, honeysuckle to be placed in -5~-10 DEG C, taking out is feasibility study
50 meshes were milled to, the salt water of dandelion, 20-25 times of honeysuckle total weight is then added, is placed under Ultrasonic Conditions and handles 30-
45min after filtering, is concentrated into original volume 1/3；
4) adlay, Herba portulacae are extracted: refrigerating 1-2h under the conditions of taking adlay, Herba portulacae to be placed in -5~-10 DEG C, taking-up can be ground to
50 meshes are crossed, the water containing tea polyphenols of adlay, 20-25 times of Herba portulacae total weight is then added, is placed under Ultrasonic Conditions and handles
30-45min after filtering, is concentrated into original volume 1/3；
5) it extracts viola mandshurica: taking viola mandshurica to refrigerate 1-2h under the conditions of -5~-10 DEG C, taking-up can be ground to 50 mesh
Sieve, then be added 20-25 times of viola mandshurica weight distilled water, using program mode heating again program mode cool down schema extraction,
After filtering, it is concentrated into original volume 1/3；
6) mixed processing: after the extract of step 1) to step 5) is handled 4-8min under microwave condition, then it is placed in ultrasonic wave
Under the conditions of handle 3-7min, be dried in vacuo to obtain composition.
4. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 3, which is characterized in that the step 1)
Middle ultrasonic wave operating condition are as follows: frequency 55-65kHz.
5. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 3, which is characterized in that the step 1)
The mass concentration of middle organic acid soln is 40-50%.
6. preventing the preparation method of the Chinese medicine composition of face acnes as claimed in claim 3 or 5, which is characterized in that the step
It is rapid 1) in organic acid soln be tartaric acid and citric acid 1:(1-1.5 in mass ratio) composition.
7. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 3, which is characterized in that the step 2)
Middle ultrasonic wave operating condition are as follows: frequency 30-35kHz.
8. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 3, which is characterized in that the step 2)
In every liter of mineral water contain following ingredient: calcium 8-12mg, sodium 3-7mg, potassium 10-15mg, magnesium 15-25mg, chlorine≤0.02mg.
9. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 3, which is characterized in that the step 3)
Middle ultrasonic wave operating condition are as follows: frequency 60-70kHz.
10. the preparation method of the Chinese medicine composition of prevention face acnes as claimed in claim 3, which is characterized in that the step
3) mesohalobic mass concentration is 20-30%.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111450006A (en) * | 2020-04-29 | 2020-07-28 | 江南大学 | Composition with multi-target acne removing effect and preparation method and application thereof |
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| CN105770209A (en) * | 2016-04-08 | 2016-07-20 | 黄庆辉 | Traditional Chinese medicine for treating chronic suppurative parotitis |
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| CN105770209A (en) * | 2016-04-08 | 2016-07-20 | 黄庆辉 | Traditional Chinese medicine for treating chronic suppurative parotitis |
| CN108721395A (en) * | 2018-08-07 | 2018-11-02 | 鑫荣生物科技（广州）有限公司 | Chinese medicine acne-removing liquid and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111450006A (en) * | 2020-04-29 | 2020-07-28 | 江南大学 | Composition with multi-target acne removing effect and preparation method and application thereof |
| CN111450006B (en) * | 2020-04-29 | 2021-07-13 | 江南大学 | Composition with multi-target acne removing effect and preparation method and application thereof |
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