CN110301931A - Coordinate registration die body, multi-mode imaging system and its method for registering images - Google Patents
Coordinate registration die body, multi-mode imaging system and its method for registering images Download PDFInfo
- Publication number
- CN110301931A CN110301931A CN201910670316.4A CN201910670316A CN110301931A CN 110301931 A CN110301931 A CN 110301931A CN 201910670316 A CN201910670316 A CN 201910670316A CN 110301931 A CN110301931 A CN 110301931A
- Authority
- CN
- China
- Prior art keywords
- die body
- coordinate
- support bar
- scan vision
- detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003384 imaging method Methods 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title claims abstract description 23
- 239000000941 radioactive substance Substances 0.000 claims abstract description 20
- 238000000926 separation method Methods 0.000 claims abstract description 14
- 230000004438 eyesight Effects 0.000 claims description 99
- 230000000007 visual effect Effects 0.000 claims description 10
- 230000001154 acute effect Effects 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000009434 installation Methods 0.000 abstract description 9
- 238000007789 sealing Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 6
- 238000002591 computed tomography Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000005484 gravity Effects 0.000 description 4
- 208000020442 loss of weight Diseases 0.000 description 4
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 241000208340 Araliaceae Species 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 210000002837 heart atrium Anatomy 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- PMMURAAUARKVCB-UHFFFAOYSA-N alpha-D-ara-dHexp Natural products OCC1OC(O)CC(O)C1O PMMURAAUARKVCB-UHFFFAOYSA-N 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000002600 positron emission tomography Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010408 sweeping Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/037—Emission tomography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/58—Testing, adjusting or calibrating thereof
- A61B6/582—Calibration
- A61B6/583—Calibration using calibration phantoms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Radiology & Medical Imaging (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- High Energy & Nuclear Physics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Theoretical Computer Science (AREA)
- Nuclear Medicine (AREA)
Abstract
Present disclose provides a kind of coordinate registration die body, multi-mode imaging system and its method for registering images, belong to medical instruments field.The coordinate registration die body includes bracket and multiple die bodys.Bracket includes first support bar, the second support bar intersected with first support bar and extending direction and the intersection of the extending direction of first support bar and at least three third support rods with the intersection of the extending direction of second support bar, second support bar connects with third support rod, and at least two third support rods are separated along second support bar and laid.The separation of at least two die bodys is laid in first support bar in multiple die bodys, and at least three die bodys are laid at least three third support rods, and at least two die bodys are separated along the extending direction of third support rod and laid.Die body includes that the cavity for accommodating radioactive substance and the through-hole for being connected to cavity, through-hole are set on the roof of ontology.The structure of the coordinate registration die body is simple, and convenient, flexible installation, scanned range is big, conducive to being accurately registrated to image.
Description
Technical field
This disclosure relates to medical instruments field more particularly to a kind of coordinate registration die body, multi-mode imaging system and its figure
As method for registering.
Background technique
Multi-mode imaging system includes multiple and different detector, in conjunction with the respective advantage of multiple imaging patterns, is conducive to
It is accurately determined the lesions position of patient.For example, PET-CT (Positron Emission Tomography-Computed
Tomography, positron emission tomography-x-ray computer tomography) equipment includes pet detector and CT detector.
But since pet detector is different with the mounting means of CT detector, it is easy to cause the same detection position in visual field
Imaging position it is different, be unfavorable for determining lesions position.The scan vision of pet detector can be determined using coordinate registration die body
And the deviation of the scan vision of CT detector is conducive to by PET image and CT image registration, so that the same detection position is being imaged
Imaging position in the visual field is identical, and realization PET image is merged with CT image.
Summary of the invention
It is a kind of that present disclose provides structures is simple, convenient, flexible installation, scanned range are big coordinate registration die body, more
Modality imaging system and its method for registering images.
An aspect of this disclosure provides a kind of coordinate registration die body, is used for multi-mode imaging system, the coordinate registration
Die body includes:
Bracket, comprising: first support bar, the second support bar intersected with the first support bar and extending direction and institute
At least three thirds support stating the extending direction intersection of first support bar and intersecting with the extending direction of the second support bar
Bar, wherein the second support bar connects with the third support rod, and at least two third support rods are along described second
Support rod separation is laid；And
Multiple die bodys, at least two die body separation are laid in the first support bar, at least three die body cloth
Set on at least three third support rods, and at least two die bodys separate cloth along the extending direction of the third support rod
If；The die body includes: ontology, and the ontology includes: the logical of cavity for accommodating radioactive substance and the connection cavity
Hole, the through-hole are set on the roof of the ontology.
Optionally, the roof of the ontology is equipped with the first groove being recessed inwardly, and the through-hole is recessed through described first
The bottom wall of slot.
Optionally, along the direction for being directed toward the cavity, the side wall of first groove is gradually to contract.
Optionally, the bottom wall of the ontology is equipped with and symmetrical second groove of first groove.
Optionally, the material of the ontology includes organic glass；The radioactive substance includes F18 radioactive substance.
Optionally, at least two third support rods are divided into the two sides of one end of the first support bar, and at least one
The end of a third support rod connects with the other end of the second support bar.
Optionally, the middle part vertical connection at the middle part of the first support bar and the second support bar；
The end of at least three third support rods with the second support bar vertical connection.
Optionally, two ends of the first support bar are equipped with the die body, at least three third support rods
The die body is equipped with away from the end of the second support bar.
Another aspect of the disclosure provides a kind of multi-mode imaging system, and the multi-mode imaging system includes:
It is scanning bed；
First detector and the second detector, first detector include the first scan vision, second detector
It is described scanning bed to be movable in first scan vision and second scan vision including the second scan vision；
The above-mentioned any coordinate registration die body referred to, be set to it is described it is scanning bed on；And
Processor is electrically connected with first detector and second detector, and the processor is used for: described in acquisition
First space coordinate of the die body in first scan vision in coordinate registration die body；Obtain mould in the coordinate registration die body
Second space coordinate of the body in second scan vision；According to first space coordinate and the second space coordinate,
Determine the first parameter error value between first scan vision and second scan vision；It is inclined according to first parameter
Difference adjusts the position of second detector, is registrated second scan vision with first scan vision.
Optionally, the axis of the first support bar of the coordinate registration die body it is described it is scanning bed on projection swept with described
It retouches and forms angle between the axis of bed, the angle is acute angle or right angle.
Another aspect of the disclosure provides a kind of method for registering images of multi-mode imaging system, refers to for above-mentioned
In any multi-mode imaging system, which comprises
Obtain first space coordinate of the die body in the first scan vision of the first detector in coordinate registration die body；
Obtain second space coordinate of the die body in the second scan vision of the second detector in the coordinate registration die body；
According to first space coordinate and the second space coordinate, first scan vision and described second is determined
The first parameter error value between scan vision；
According to the first parameter error value, adjust the position of second detector, make second scan vision with
The first scan vision registration.
Optionally, the method also includes:
According to first space coordinate and the second space coordinate, determine that scanning bed scan with described first regards
The second parameter error value between open country；
According to the second parameter error value, the scanning bed position is adjusted, makes described scanning bed sweep with described first
Retouch visual field registration.
The coordinate registration die body that the embodiment of the present disclosure provides at least has the advantages that
The coordinate registration die body that the embodiment of the present disclosure provides, intersected by first support bar in bracket with second support bar,
The extending direction of at least three third support rods intersects with the extending direction of first support bar and the extension side with second support bar
To intersection, make bracket three-dimensional, and the structure of bracket is simple.The first support is set to by least two separation in multiple die bodys
Bar, at least three are laid at least three third support rods, and at least two die bodys are separated along the extending direction of third support rod
It lays, this makes multiple die body separation be laid in the different location of bracket, the scanned range of coordinate registration die body is expanded,
Image registration is accurately carried out conducive to using the coordinate registration die body.The roof of die body ontology is equipped with through-hole, and injection is facilitated to put
Penetrating property substance, and setting sealing element can not had to, it is conducive to die body loss of weight and installation.The structure of the coordinate registration die body is simple, convenient
It manufactures and flexibly installs and uses, and scanned range can be expanded, conducive to being accurately registrated to image.
Detailed description of the invention
Fig. 1 show the structural schematic diagram of disclosure multi-mode imaging system shown according to an exemplary embodiment；
Fig. 2 show the structural schematic diagram of disclosure coordinate registration die body shown according to an exemplary embodiment；
Fig. 3 show the structural schematic diagram of disclosure die body shown according to an exemplary embodiment；
Fig. 4 show the method for registering images of disclosure multi-mode imaging system shown according to an exemplary embodiment
Flow chart；
Fig. 5 show the adjustment point distribution map of disclosure multi-mode imaging system shown according to an exemplary embodiment.
Specific embodiment
Example embodiments are described in detail here, and the example is illustrated in the accompanying drawings.Following description is related to
When attached drawing, unless otherwise indicated, the same numbers in different drawings indicate the same or similar elements.Following exemplary embodiment
Described in embodiment do not represent all implementations consistent with this disclosure.On the contrary, they be only with it is such as appended
The example of the consistent device and method of some aspects be described in detail in claims, the disclosure.
It is only to be not intended to be limiting the disclosure merely for for the purpose of describing particular embodiments in the term that the disclosure uses.
Unless otherwise defined, the technical term or scientific term that the disclosure uses, which are should be in disclosure fields, has general skill
The ordinary meaning that the personage of energy is understood." first " " second " and class used in present disclosure specification and claims
As word be not offered as any sequence, quantity or importance, and be used only to distinguish different component parts.Equally, " one
It is a " or the similar word such as " one " do not indicate that quantity limits yet, but indicate that there are at least one.Unless otherwise noted, " packet
Including " element or object that either the similar word such as "comprising" means to appear in front of " comprising " or "comprising" cover and appear in
The element or object of " comprising " or "comprising" presented hereinafter and its equivalent, it is not excluded that other elements or object." even
Connect " either the similar word such as " connected " be not limited to physics or mechanical connection, and may include electrical company
It connects, it is either direct or indirect.
In present disclosure specification and the "an" of singular used in the attached claims, " described " and "the"
It is also intended to including most forms, unless the context clearly indicates other meaning.It is also understood that term used herein
"and/or" refers to and includes that one or more associated any or all of project listed may combine.
In some embodiments, coordinate registration die body includes: pedestal, shell, sealing cover and multiple examinations equipped with developer
Pipe.Wherein, one end of pedestal and shell connects, and shell includes atrium, and sealing cover is covered on atrium, sealing cover and shell shape
At seal cavity.Sealing cover is equipped with multiple mounting holes, and multiple test tubes pass through mounting hole side by side and extend in seal cavity.It should
Coordinate registration die body can be used in multi-mode imaging system.But structure is complicated for the coordinate registration die body, cannot flexibly install
Different location in multi-mode imaging system, and multiple test tubes be arranged side by side, make the coordinate registration die body it is multi-modal at
Scanned range is small in picture system, is unfavorable for accuracy registration image.Based on this, the embodiment of the present disclosure provides a kind of coordinate and matches
Quasi-mode body, multi-mode imaging system and its method for registering images.
The coordinate registration die body that the embodiment of the present disclosure provides is used in multi-mode imaging system, the coordinate registration die body packet
It includes: bracket and multiple die bodys.Wherein, bracket includes: first support bar, the second support bar intersected with first support bar and prolongs
Stretch at least three third branch that direction is intersected with the extending direction of first support bar and intersected with the extending direction of second support bar
Strut, wherein second support bar connects with third support rod, and at least two third support rods are separated along second support bar and laid.
The separation of at least two die bodys is laid in first support bar in multiple die bodys, and at least three die bodys are laid in the support of at least three thirds
Bar, and at least two die bodys are separated along the extending direction of third support rod and are laid.Die body includes: ontology, and ontology includes: for holding
Receive radioactive substance cavity and be connected to cavity through-hole, through-hole be set to ontology roof on.The seat that the embodiment of the present disclosure provides
Standard configuration quasi-mode body is intersected by first support bar in bracket with second support bar, the extending direction of at least three third support rods
Intersect with the extending direction of first support bar and intersect with the extending direction of second support bar, makes bracket three-dimensional, and bracket
Structure is simple.It is set to first support bar by least two separation in multiple die bodys, at least three are laid at least three thirds
Support rod, and at least two die bodys are separated along the extending direction of third support rod and are laid, this is laid in multiple die body separation
The different location of bracket expands the scanned range of coordinate registration die body, is conducive to using the coordinate registration die body accurately
Carry out image registration.The roof of die body ontology is equipped with through-hole, facilitates injection radioactive substance, and can not have to setting sealing element,
Conducive to die body loss of weight and installation.The structure of the coordinate registration die body is simple, facilitates the manufacturing and flexibly installs and uses, and can expand
Big scanned range, conducive to being accurately registrated to image.
Fig. 1 show the structural schematic diagram of disclosure multi-mode imaging system shown according to an exemplary embodiment, ginseng
Fig. 1 is examined, which includes: the scanning bed 1, first detector 2, the second detector 3, coordinate registration die body 4, processing
Device (not shown).Wherein, the first detector 2 includes the first scan vision, and the second detector 3 includes the second scan vision, scanning
Bed 1 is movable in the first scan vision and the second scan vision.Coordinate registration die body 4 is set on scanning bed 1.Processor and
One detector 2 and the electrical connection of the second detector 3, processor are used for: die body is in the first scan vision in acquisition coordinate registration die body 4
In the first space coordinate；Obtain second space coordinate of the die body in the second scan vision in coordinate registration die body 4；According to
One space coordinate and second space coordinate determine the first parameter error value between the first scan vision and the second scan vision；
According to the first parameter error value, the position of the second detector 3 is adjusted, is registrated the second scan vision with the first scan vision.
It should be noted that the scanning range of the first scan vision and the second scan vision may be the same or different, coordinate
It is registrated die body 4 and is suitable for the first scan vision and the second scan vision.
Wherein, the first detector 2 can be CT scan (Computed Tomography, CT) equipment, the
Two detectors 3 can be Positron Emission Computed Tomography (Positron Emission Tomography, PET) equipment.
Alternatively, the first detector 2 can be PET device, the second detector 3 can be CT equipment.First detector 2 and the second detector 3 are also
It can be other image detectors, it is not limited in this embodiment of the present disclosure.
Coordinate registration die body 4 can be set to scanning bed 1 head of a bed, and with when scanning bed 1 is mobile, coordinate registration die body 4 can be into
Enter in the first scan vision and the second scan vision.The first scan vision and can be registrated by using coordinate registration die body 4
Two scan visions even if the coordinate origin of the first scan vision is overlapped with the coordinate origin of the second scan vision, and make first to sweep
The x-axis, y-axis, z-axis for retouching the visual field are overlapped with the x-axis of the second scan vision, y-axis, z-axis respectively.
Fig. 2 show the structural schematic diagram of disclosure coordinate registration die body 4 shown according to an exemplary embodiment, the seat
Standard configuration quasi-mode body 4 is used for multi-mode imaging system.With reference to Fig. 2, which includes: bracket 41 and multiple die bodys 42.
Wherein, bracket 41 include: first support bar 411, the second support bar intersected with first support bar 411 412 and extending direction with
At least three thirds support that the extending direction of first support bar 411 intersects and intersects with the extending direction of second support bar 412
Bar 413, second support bar 412 connect with third support rod 413, and at least two third support rods 413 are along second support bar 412
Separation is laid.The separation of at least two die bodys 42 is laid in first support bar 411 in multiple die bodys 42, and at least three die bodys 42 are laid
In at least three third support rods 413, and at least two die bodys 42 are separated along the extending direction of third support rod 413 and are laid.
In one embodiment, with continued reference to Fig. 2, at least two third support rods 413 are divided into second support bar 412
The end of the two sides of one end, at least one third support rod 413 connects with the other end of second support bar 412, this makes bracket 41
Compound with regular structure, facilitate the manufacturing of bracket 41 and install and use.It should be noted that being set to 412 one end of second support bar
At least two third support rods 413 of two sides can be opposite, can not also be opposite.
In one embodiment, it hangs down with continued reference to Fig. 2, the middle part of first support bar 411 and the middle part of second support bar 412
Directly connect；The end of at least three third support rods 413 with 412 vertical connection of second support bar.In this way, making the bracket 41
Structure it is simple, facilitate the manufacturing, moreover, multiple die bodys 42 can be each extended in transverse direction, longitudinal direction, front-rear direction is laid in this
On bracket 41, it is conducive to expand the scanned range of coordinate registration die body 4.Wherein, first support bar 411 and second support bar
412 are detachably connected, and second support bar 412 is detachably connected with third support rod 413, such as clamping connection.First support bar
411, second support bar 412, the length of third support rod 413 is adjustable so that the coordinate registration die body 4 is suitable for different sweeping
Retouch the visual field.
In one embodiment, with continued reference to Fig. 2, two ends of first support bar 411 are equipped with die body 42, at least three
A third support rod 413 is equipped with die body 42 away from the end of second support bar 412.In this way, being conducive to increase the coordinate registration mould
The range that body 4 is scanned by multi-mode imaging system.For example, multi-mode imaging system includes cylindric scan vision, it is cylindric to sweep
It is circle, the cross of the reliable subcircular of die body 42 of 411 two ends of first support bar that the visual field, which is retouched, along the cross section perpendicular to axial direction
Matched to edge set on the longitudinal edge of the reliable subcircular of die body 42 of at least two third support rods, 413 end with expanding coordinate
The scanned range in scan vision of quasi-mode body 4.
In one embodiment, with continued reference to Fig. 2, coordinate registration die body 4 includes: first support bar 411, second support bar
412 and three third support rods 413.Wherein, the middle part of first support bar 411 phase vertical with the middle part of second support bar 412
It connects, the upper end vertical connection of two third support rods 413 and second support bar 412, and is set to the two sides of second support bar 412,
The lower end vertical connection of one third support rod 413 and second support bar 412.The structure of the coordinate registration die body 4 is simple, convenient
Neatly be installed on it is multi-modal in system scanning bed 1 different location.
In the embodiments of the present disclosure, die body 42 can be fixed on bracket 41 by fixing piece, for example pass through fixing piece for mould
Body 42 is held on bracket 41.Fixing piece can include: cover board and screw, cover board are placed on die body 42, and screw pass through cover board with
Bracket 41 is threadedly coupled.In another embodiment, bracket 41 is equipped with card slot, and die body 42 is connected in card slot.
Fig. 3 show the structural schematic diagram of disclosure die body 42 shown according to an exemplary embodiment.Implement at one
In example, with reference to Fig. 3, die body 42 includes: ontology 421, and ontology 421 includes: the cavity 422 and connection for accommodating radioactive substance
The through-hole 423 of cavity 422, through-hole 423 are set on the roof of ontology 421.Through-hole 423 is set on the roof of ontology 421, can be subtracted
The radioactive substance being contained in the cavity 422 of ontology 421 less is sputtered by through-hole 423, does not have to setting sealing through-hole 423 also
Sealing element is conducive to 42 loss of weight of die body and installation, and the structure of the die body 42 is simple, facilitates the manufacturing and use.Wherein, ontology
421 can be the rule such as square body, column or irregular structure.The material of ontology 421 includes organic glass or transparent plastic,
Not influence to scan radioactive substance.Radioactive substance includes F18 radioactive substance, such as F18-FDG (2-Fluorine-
18Fluoro-2-deeoxy-D-glucose, 2- Value linear-fluoro- 2-deoxy-D-glucose) solution, the radioactive substance be easy
It obtains.It is laid on bracket 41 by the separation of multiple die bodys 42, compared with the test tube equipped with radioactive substance is set, is not only expanded
Scanned range is additionally favorable for reducing the usage amount of radioactive substance, reduces cost.
The coordinate registration die body 4 that the embodiment of the present disclosure provides, passes through first support bar 411 and second support bar in bracket 41
412 intersections, at least three third support rods 413 extending direction intersect with the extending direction of first support bar 411 and with second
The extending direction of support rod 412 intersects, and makes 41 three-dimensional of bracket, and the structure of bracket 41 is simple.By in multiple die bodys 42 extremely
Few two separation are set to first support bar 411, and at least three are laid at least three third support rods 413, and at least two moulds
Body 42 is separated along the extending direction of third support rod 413 and is laid, this makes multiple die bodys 42 separate the difference for being laid in bracket 41
Position expands the scanned range of coordinate registration die body 4, accurately carries out image conducive to using the coordinate registration die body 4
Registration.The roof of 42 ontology 421 of die body is equipped with through-hole 423, facilitates injection radioactive substance, and can not have to setting sealing element,
Conducive to 42 loss of weight of die body and installation.The structure of the coordinate registration die body 4 is simple, facilitates the manufacturing and is flexibly installed on use,
And scanned range can be expanded, conducive to being accurately registrated to image.
In one embodiment, with continued reference to Fig. 3, the roof of ontology 421 is equipped with the first groove 424 being recessed inwardly,
Through-hole 423 runs through the bottom wall of the first groove 424.The radioactive substance sputtered by through-hole 423 can be in 424 cohesion of the first groove
Collection, and be again introduced into through-hole 423, it avoids polluting the external world.
In one embodiment, with continued reference to Fig. 3, along the direction for being directed toward cavity 422, the side wall of the first groove 424 is gradually
To contract, so that radioactive substance is assembled in the first groove 424, and it is again introduced into through-hole 423.Wherein, first is recessed
The cross section of slot 424 can be square structure, circular configuration and other rules or irregular structure, and the embodiment of the present disclosure is to this
It is not especially limited.
In one embodiment, with continued reference to Fig. 3, the bottom wall of ontology 421 is equipped with recessed with the first groove 424 symmetrical second
Slot 425, so that the symmetrical configuration of ontology 421, can be used as a regular point source when in use, conducive to 42 center of gravity of die body is determined
Space coordinate.For example, can be using the space coordinate where the center of gravity of die body 42 as the space coordinate of die body 42.
In one embodiment, projection of the axis of the first support bar 411 of coordinate registration die body 4 on scanning bed 1 with
Angle is formed between scanning bed 1 axis, angle is acute angle or right angle.The coordinate registration die body 4 can different projection angle peaces
On scanning bed 1, installation site is flexible, is easy to use.It wherein, is detachably to connect between coordinate registration die body 4 and scanning bed 1
It connects, for example, scanning bed 1 is equipped with slot, for slot on scanning bed 1 central axes, bracket 41 is detachably inserted into slot
It is interior.For another example, scanning bed 1 it is equipped with the first shackle member, bracket 41 is equipped with the second shackle member, the second shackle member and the first shackle member card
It connects in succession, is connected in coordinate registration die body 4 on scanning bed 1.It should be noted that the first shackle member and the second shackle member are not drawn
Play image artifacts.The disclosure is not especially limited about the structure of the first shackle member and the second shackle member.
The multi-mode imaging system that the embodiment of the present disclosure provides should including the above-mentioned any coordinate registration die body 4 referred to
The convenient, flexible different location for being installed on multi-mode imaging system of coordinate registration die body 4, and scanned range can be expanded, it is conducive to
The multi-mode imaging system is accurately registrated image.
Fig. 4 show the method for registering images of disclosure multi-mode imaging system shown according to an exemplary embodiment
Flow chart, in the above-mentioned multi-mode imaging system referred to.With reference to Fig. 4, this method comprises:
Step 101, obtain coordinate registration die body 4 in die body 42 in the first scan vision of the first detector 2 first
Space coordinate.
It controls scanning bed 1 to be moved in the first scan vision of the first detector 2, makes the first detector 2 to coordinate registration
Die body 4 is scanned, and obtains the first reconstructed image of coordinate registration die body 4, by processor to the first reconstructed image at
Reason, obtains the first space coordinate of each die body 42 in coordinate registration die body 4.For example, obtaining the first of each 42 center of gravity of die body
Space coordinate.Wherein, the first space coordinate is represented by (x1, y1, z1), and x1 indicates die body 42 in the first scan vision laterally
Coordinate in x-axis, y1 indicate that coordinate of the die body 42 in the first scan vision in front-rear direction y-axis, z1 are indicated in the first scanning
Coordinate in the visual field in longitudinal z-axis.Coordinate origin is the central point of the first scan vision.
Step 102 obtains second sky in the second scan vision of the second detector 3 of die body 42 in coordinate registration die body 4
Between coordinate.
It controls scanning bed 1 to be moved in the second scan vision of the second detector 3, makes the second detector 3 to coordinate registration
Die body 4 is scanned, and obtains the second reconstructed image of coordinate registration die body 4, by processor to the second reconstructed image at
Reason, obtains the second space coordinate of each die body 42 in coordinate registration die body 4.For example, obtaining the second of each 42 center of gravity of die body
Space coordinate.Wherein, second space coordinate can be expressed as (x2, y2, z2), and x2 indicates that die body 42 is horizontal in the second scan vision
Coordinate in x-axis, y2 indicate that coordinate of the die body 42 in the second scan vision in front-rear direction y-axis, z2 indicate that die body 42 exists
Coordinate in second scan vision in longitudinal z-axis.Coordinate origin is the central point of the second scan vision.
Step 103, according to the first space coordinate and second space coordinate, determine the first scan vision and the second scan vision
Between the first parameter error value.First parameter error value includes: that the space coordinates of the first scan vision and the second scanning regard
The shifting deviation value and angu-lar deviation of wild space coordinates respective coordinates x, y, z.
With the first detector for CT detector, for the second detector is pet detector, the first scan vision and the are determined
First parameter error value of two scan visions the following steps are included:
Step a, according to formula I and transition matrix M, by second space coordinate of the die body 42 in the second scan vision
(xPET, yPET, zPET) be converted to the third space coordinate (x ' in the first scan visionCT, y 'CT, z 'CT)。
(x′CT, y 'CT, z 'CT)=M × (xPET, yPET, zPET) (formula I)
Step b, the first space coordinate (x of die body 42 is calculated according to formula IICT, yCT, zCT) and third space coordinate
(x′CT, y 'CT, z 'CT) grid deviation expression formula.
F=(xCT, yCT, zCT)-(x′CT, y 'CT, z 'CT) (formula II)
Step c, according to least square method, formula II is converted to the optimal solution for solving following formula III.
Wherein, (xCT, yCT, zCT) be the first scan vision in die body 42 barycentric coodinates, (xPET, yPET, zPET) it is second
The barycentric coodinates of die body 42 in scan vision, i=1 ... ..., N, indicates coordinate are registrated the number of die body 42 in die body 4, FTFor F
Transposed matrix.
Step d, according to the optimal solution of E, transition matrix M is obtained, further determines that the coordinate system in the PET scan visual field is swept to CT
Retouch the shifting deviation of x, y, z and angular deviation in the coordinate system in the visual field.
Step 104, according to the first parameter error value, adjust the position of the second detector 3, make the second scan vision and first
Scan vision registration.
In one embodiment, the method for registering images for the multi-mode imaging system that the embodiment of the present disclosure provides further include:
Step 105, according to the first space coordinate and second space coordinate, determine scanning bed 1 and first between scan vision
The second parameter error value.Second parameter error value includes: that scanning bed 1 and the first translation between scan vision coordinate system are inclined
Difference and scanning bed 1 and the first angular deviation in scan vision coordinate system between x-axis, y-axis.
By the way that coordinate registration die body 4 to be set on scanning bed 1 central axes, and it is scanning bed to be located at least one die body 42
On 1 central axes, the first space coordinate based on the die body 42 is determined scanning bed 1 and first between scan vision coordinate system
Shifting deviation value.The first space coordinate and second space coordinate based on die body 42, determine scanning bed 1 and first scan vision it
Between deviation angle.
Step 106, according to the second parameter error value, the position of adjustment scanning bed 1 makes scanning bed 1 and first scan vision
Registration.It is registrated by making scanning bed 1 with the first scan vision, conducive to lesion is accurately determined.
The method for registering images for the multi-mode imaging system that the embodiment of the present disclosure provides, by obtaining coordinate registration die body 4
First space coordinate of the middle die body 42 in the first scan vision, and the second space coordinate in the second scan vision, and
Determine that the first parameter between the first scan vision and the second scan vision is inclined according to the first space coordinate and second space coordinate
Then difference adjusts the position of the second detector 3 according to the first parameter error value, makes the second scan vision and the first scan vision
Registration.Since the structure of the coordinate registration die body 4 is simple, it convenient, flexible can be installed on the different location of multi-mode imaging system,
Facilitate the implementation of this method, and the scanned range of coordinate registration die body 4 is big, accurately carries out figure conducive to the method for registering images
As registration.
It is not especially limited for step 103 to step 104, with the sequence of step 105 to step 106, image can be made
Registration.
In one embodiment, step 104 and step 106, comprising:
Processor exports the adjustment o'clock of the second detector 3 second according to the first parameter error value and the second parameter error value
The shifting deviation value and angu-lar deviation of scan vision and the first scan vision, it is scanning bed 1 adjustment point with the first scan vision it
Between shifting deviation value and angu-lar deviation, it is specific that see Table 1 for details.Wherein, for the adjustment point of the second detector 3 and scanning bed 1
It can be found in the adjustment point distribution map of disclosure multi-mode imaging system shown according to an exemplary embodiment shown in fig. 5.Ginseng
Fig. 5 is examined, the adjustment point of the second detector 3 includes: G1, G2, G3, G4, G5, G6, G7, GA, GB, GC, GD, GE, GF.Scanning bed 1
Adjustment point include T1, T2, T3, T4, T5, T6, TA, TB, TC, TD, TE, TF, TG, TH.
Table 1
The parameter error value for multiple adjustment points that processor is provided according to table 1 provides Adjusted Option, and specific see Table 2 for details.
Table 2
According to the Adjusted Option that table 2 provides, the position of adjustment scanning bed 1 and the second detector 3.Wherein, scanning bed 1 includes
For adjusting scanning bed 1 multiple screws, multiple screws are corresponded with scanning bed 1 multiple adjustment points.Second detector 3 packet
Include multiple screws for adjusting the second detector 3, multiple adjustment points one-to-one correspondence of multiple screws and the second detector 3.It is logical
Cross rotary screw can be adjusted scanning bed 1 and second detector 3 position.In Tables 1 and 2, negative sign expression screws out screw,
Positive sign expression screws in screw.
After adjustment scanning bed 1 and the second detector 3, if the scanning bed 1, second detector 3, the first detector 2 are also not
Registration, then processor executes step 101 to step 106 again, and reacquires the first parameter error value and the second parameter error
Value, the adjustment o'clock of the second detector 3 of output are swept in the shifting deviation and angular deviation of the second scan vision and the first scan vision
Shifting deviation and angular deviation of the adjustment point of bed 1 with the first scan vision coordinate system are retouched, specific see Table 3 for details.
Table 3
The parameter error value for multiple adjustment points that processor is provided according to table 3 provides Adjusted Option, to scanning bed 1 and second
Detector 3 is adjusted, until Adjusted Option is as shown in table 4, the first detector 2, the second detector 3 and scanning bed 1 it is flat
Moving deviation and angu-lar deviation adjustment is 0, i.e. the registration completely of the first scan vision, the second scan vision, scanning bed 1.
Table 4
For embodiment of the method, since it corresponds essentially to Installation practice, so related place is referring to device reality
Apply the part explanation of example.Embodiment of the method and Installation practice complement one another.
The foregoing is merely the preferred embodiments of the disclosure, not to limit the disclosure, all essences in the disclosure
Within mind and principle, any modification, equivalent substitution, improvement and etc. done be should be included within the scope of disclosure protection.
Claims (12)
1. a kind of coordinate registration die body, it to be used for multi-mode imaging system, which is characterized in that the coordinate registration die body includes:
Bracket, comprising: first support bar, the second support bar intersected with the first support bar and extending direction and described the
At least three third support rods that the extending direction of one support rod intersects and intersects with the extending direction of the second support bar,
Described in second support bar connect with the third support rod, and at least two third support rods are along the second support bar
Separation is laid；And
Multiple die bodys, at least two die body separation are laid in the first support bar, and at least three die bodys are laid in
At least three third support rods, and at least two die bodys are separated along the extending direction of the third support rod and are laid；
The die body includes: ontology, and the ontology includes: the through-hole of the cavity and the connection cavity for accommodating radioactive substance,
The through-hole is set to the roof of the ontology.
2. coordinate registration die body according to claim 1, which is characterized in that the roof of the ontology is equipped with and is recessed inwardly
First groove, the through-hole run through the bottom wall of first groove.
3. coordinate registration die body according to claim 2, which is characterized in that along the direction for being directed toward the cavity, described the
The side wall of one groove is gradually to contract.
4. coordinate registration die body according to claim 2, which is characterized in that the bottom wall of the ontology is equipped with and described first
Symmetrical second groove of groove.
5. coordinate registration die body according to claim 1, which is characterized in that the material of the ontology includes organic glass；
The radioactive substance includes F18 radioactive substance.
6. coordinate registration die body according to claim 1-5, which is characterized in that at least two third supports
Bar is divided into the two sides of one end of the second support bar, the end of at least one third support rod and second support
The other end of bar connects.
7. coordinate registration die body according to claim 6, which is characterized in that the middle part of the first support bar and described the
The middle part vertical connection of two support rods；
The end of at least three third support rods with the second support bar vertical connection.
8. coordinate registration die body according to claim 6, which is characterized in that two ends of the first support bar are all provided with
There is the die body, at least three third support rods are equipped with the die body away from the end of the second support bar.
9. a kind of multi-mode imaging system, which is characterized in that the multi-mode imaging system includes:
It is scanning bed；
First detector and the second detector, first detector include the first scan vision, and second detector includes
Second scan vision, it is described scanning bed to be movable in first scan vision and second scan vision；
The described in any item coordinate registration die bodys of claim 1-8, be set to it is described it is scanning bed on；And
Processor is electrically connected with first detector and second detector, and the processor is used for: obtaining the coordinate
It is registrated first space coordinate of the die body in first scan vision in die body；Die body in the coordinate registration die body is obtained to exist
Second space coordinate in second scan vision；According to first space coordinate and the second space coordinate, determine
The first parameter error value between first scan vision and second scan vision；According to first parameter error
Value adjusts the position of second detector, is registrated second scan vision with first scan vision.
10. multi-mode imaging system according to claim 9, which is characterized in that first of the coordinate registration die body
The axis of strut it is described it is scanning bed on projection and the scanning bed axis between form angle, the angle be acute angle or
Right angle.
11. a kind of method for registering images of multi-mode imaging system, which is characterized in that for more described in claim 9 or 10
In modality imaging system, which comprises
Obtain first space coordinate of the die body in the first scan vision of the first detector in coordinate registration die body；
Obtain second space coordinate of the die body in the second scan vision of the second detector in the coordinate registration die body；
According to first space coordinate and the second space coordinate, first scan vision and second scanning are determined
The first parameter error value between the visual field；
According to the first parameter error value, adjust the position of second detector, make second scan vision with it is described
First scan vision registration.
12. according to the method for claim 11, which is characterized in that the method also includes:
According to first space coordinate and the second space coordinate, determine it is described it is scanning bed with first scan vision it
Between the second parameter error value；
According to the second parameter error value, the scanning bed position is adjusted, regards scanning bed scan with described first
Open country registration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910670316.4A CN110301931B (en) | 2019-07-24 | 2019-07-24 | Coordinate registration die body, multi-mode imaging system and image registration method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910670316.4A CN110301931B (en) | 2019-07-24 | 2019-07-24 | Coordinate registration die body, multi-mode imaging system and image registration method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110301931A true CN110301931A (en) | 2019-10-08 |
| CN110301931B CN110301931B (en) | 2023-10-31 |
Family
ID=68081603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910670316.4A Active CN110301931B (en) | 2019-07-24 | 2019-07-24 | Coordinate registration die body, multi-mode imaging system and image registration method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110301931B (en) |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090087061A1 (en) * | 2007-09-27 | 2009-04-02 | Siemens Medical Solutions Usa, Inc. | Intrinsic Co-Registration For Modular Multimodality Medical Imaging Systems |
| JP2009284958A (en) * | 2008-05-27 | 2009-12-10 | Hitachi Medical Corp | Magnetic resonance imaging system and phantom |
| CN102631211A (en) * | 2012-04-13 | 2012-08-15 | 四川中测辐射科技有限公司 | CR/DR (Computed Radiography/Direct Radiography) comprehensive detection die body |
| JP2016036672A (en) * | 2014-08-11 | 2016-03-22 | 株式会社島津製作所 | Phantom for radiography |
| CN105496438A (en) * | 2015-12-28 | 2016-04-20 | 沈阳东软医疗系统有限公司 | Multi-mode medical image overlapping state detecting method and device |
| CN106923854A (en) * | 2017-03-21 | 2017-07-07 | 泰山医学院 | A kind of comprehensive Quality Control body mould suitable for PET/CT |
| CN107374656A (en) * | 2017-05-26 | 2017-11-24 | 赛诺联合医疗科技（北京）有限公司 | The coordinate registration die body of multi-modal detection system |
| CN207306994U (en) * | 2016-11-10 | 2018-05-04 | 北京康科达科技有限公司 | A kind of gamma knife dose measuring systems |
| CN207575160U (en) * | 2017-03-21 | 2018-07-06 | 泰山医学院 | A kind of PET/MR image quality detection body mould on apery head |
| CN207675917U (en) * | 2018-01-24 | 2018-07-31 | 浙江优纳特科学仪器有限公司 | A kind of Magnetic resonance imaging quality testing die body |
-
2019
- 2019-07-24 CN CN201910670316.4A patent/CN110301931B/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090087061A1 (en) * | 2007-09-27 | 2009-04-02 | Siemens Medical Solutions Usa, Inc. | Intrinsic Co-Registration For Modular Multimodality Medical Imaging Systems |
| JP2009284958A (en) * | 2008-05-27 | 2009-12-10 | Hitachi Medical Corp | Magnetic resonance imaging system and phantom |
| CN102631211A (en) * | 2012-04-13 | 2012-08-15 | 四川中测辐射科技有限公司 | CR/DR (Computed Radiography/Direct Radiography) comprehensive detection die body |
| JP2016036672A (en) * | 2014-08-11 | 2016-03-22 | 株式会社島津製作所 | Phantom for radiography |
| CN105496438A (en) * | 2015-12-28 | 2016-04-20 | 沈阳东软医疗系统有限公司 | Multi-mode medical image overlapping state detecting method and device |
| CN207306994U (en) * | 2016-11-10 | 2018-05-04 | 北京康科达科技有限公司 | A kind of gamma knife dose measuring systems |
| CN106923854A (en) * | 2017-03-21 | 2017-07-07 | 泰山医学院 | A kind of comprehensive Quality Control body mould suitable for PET/CT |
| CN207575160U (en) * | 2017-03-21 | 2018-07-06 | 泰山医学院 | A kind of PET/MR image quality detection body mould on apery head |
| CN107374656A (en) * | 2017-05-26 | 2017-11-24 | 赛诺联合医疗科技（北京）有限公司 | The coordinate registration die body of multi-modal detection system |
| CN207675917U (en) * | 2018-01-24 | 2018-07-31 | 浙江优纳特科学仪器有限公司 | A kind of Magnetic resonance imaging quality testing die body |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110301931B (en) | 2023-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105913439B (en) | A kind of large-field shooting machine scaling method based on laser tracker | |
| CN102144927B (en) | Motion-compensation-based computed tomography (CT) equipment and method | |
| US10842462B2 (en) | Self-calibrating technique for x-ray imaging scanners | |
| JP5643772B2 (en) | MR coil attenuation correction in hybrid PET / MR system | |
| JP2016538066A (en) | Intervention X-ray system with automatic isocentering | |
| WO2013019985A9 (en) | 2d/3d registration of a digital mouse atlas with x-ray projection images and optical camera photos | |
| CN103829966B (en) | For automatically determining the method and system of the position line in detecting image | |
| JP2009545358A (en) | Rotating X-ray scanning planning system | |
| Vija et al. | A method for improving the efficiency of myocardial perfusion imaging using conventional SPECT and SPECT/CT imaging systems | |
| CN103156632B (en) | Lumbar vertebra three-dimensional measurement method | |
| JP2010540893A (en) | Image reconstruction method by X-ray volume imaging | |
| CN102697514A (en) | Selection of optimal viewing angle to optimize anatomy visibility and patient skin dose | |
| CN109102567A (en) | A kind of pose parameter high-precision method for solving minimized based on reconstruction error | |
| US7449681B1 (en) | Multi-modal imaging registration calibration device and method | |
| WO2012155137A2 (en) | Radiographic phantom apparatuses | |
| CN105496438B (en) | Multi-modality medical image coincidence status detection method and device | |
| CN110025327B (en) | PET/CT registration device and method | |
| US11432789B2 (en) | Self-calibrating technique for x-ray imaging scanners | |
| CN110301931A (en) | Coordinate registration die body, multi-mode imaging system and its method for registering images | |
| CN202305443U (en) | CT (computed tomography) system | |
| Könik et al. | Digital anthropomorphic phantoms of non-rigid human respiratory and voluntary body motion for investigating motion correction in emission imaging | |
| JP6155427B1 (en) | Medical slice display device and slice image display method | |
| CN104502378B (en) | X-ray CT (Computed Tomography) device | |
| CN207462086U (en) | A kind of synthesis Quality Control body mould suitable for PET/CT | |
| JP5455290B2 (en) | Medical image processing apparatus and medical image diagnostic apparatus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20230428 Address after: Room 308, No. 177-2 Chuangxin Road, Hunnan District, Shenyang City, Liaoning Province, 110167 Applicant after: Shenyang Zhihe Medical Technology Co.,Ltd. Address before: 110167 No. 177-1 Innovation Road, Hunnan District, Shenyang City, Liaoning Province Applicant before: Shenyang Neusoft Medical Systems Co.,Ltd. |
|
| TA01 | Transfer of patent application right | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |